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Apple Computer Inc. has always blazed its own trail, a tack that has helped turn the company into a stock-market darling lately. But a pivotal step toward the mainstream could be in the offing.

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The computer maker has been in talks that could lead to a decision soon to use Intel Corp. chips in its Macintosh computer line, industry executives say, a prospect that may shake up the world of computers and software.

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The idea that...