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217.00 300.60 Td (90 ) Tj ET Q q 0 0 0 rg BT 228.25 300.60 Td (days.    ) Tj ET Q q 0 0 0 rg BT 256.67 300.60 Td (Y) Tj ET Q q 0 0 0 rg BT 262.17 300.60 Td (es  ) Tj ET Q /GS0 gs q 9.54 0 0 9.04 274.17 298.66 cm /I5 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 283.71 300.60 Td (    No  ) Tj ET Q /GS0 gs q 8.02 0 0 9.04 308.21 298.66 cm /I6 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 286.80 Td (Indicate ) Tj ET Q q 0 0 0 rg BT 93.28 286.80 Td (by ) Tj ET Q q 0 0 0 rg BT 104.57 286.80 Td (check ) Tj ET Q q 0 0 0 rg BT 128.35 286.80 Td (mark ) Tj ET Q q 0 0 0 rg BT 151.13 286.80 Td (whether) Tj ET Q q 0 0 0 rg BT 182.46 286.80 Td ( ) Tj ET Q q 0 0 0 rg BT 184.25 286.80 Td (the ) Tj ET Q q 0 0 0 rg BT 198.03 286.80 Td (r) Tj ET Q q 0 0 0 rg BT 201.86 286.80 Td (egistrant ) Tj ET Q q 0 0 0 rg BT 237.64 286.80 Td (has ) Tj ET Q q 0 0 0 rg BT 252.43 286.80 Td (submitted ) Tj ET Q q 0 0 0 rg BT 292.72 286.80 Td (electr) Tj ET Q q 0 0 0 rg BT 314.03 286.80 Td (onically ) Tj ET Q q 0 0 0 rg BT 345.82 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Td (and ) Tj ET Q q 0 0 0 rg BT 183.20 276.00 Td (posted ) Tj ET Q q 0 0 0 rg BT 209.85 276.00 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 246.52 276.00 Td (to ) Tj ET Q q 0 0 0 rg BT 255.66 276.00 Td (Rule ) Tj ET Q q 0 0 0 rg BT 275.31 276.00 Td (405 ) Tj ET Q q 0 0 0 rg BT 290.45 276.00 Td (of ) Tj ET Q q 0 0 0 rg BT 299.60 276.00 Td (Regulation ) Tj ET Q q 0 0 0 rg BT 343.25 276.00 Td (S-T) Tj ET Q q 0 0 0 rg BT 357.09 276.00 Td ( ) Tj ET Q q 0 0 0 rg BT 358.74 276.00 Td (\(§232.405 ) Tj ET Q q 0 0 0 rg BT 397.13 276.00 Td (of ) Tj ET Q q 0 0 0 rg BT 406.28 276.00 Td (this ) Tj ET Q q 0 0 0 rg BT 421.93 276.00 Td (chapter\) ) Tj ET Q q 0 0 0 rg BT 456.06 276.00 Td (during ) Tj ET Q q 0 0 0 rg BT 483.72 276.00 Td (the ) Tj ET Q q 0 0 0 rg BT 497.37 276.00 Td (pr) Tj ET Q q 0 0 0 rg BT 506.20 276.00 Td (eceding ) Tj ET Q q 0 0 0 rg BT 536.85 276.00 Td (12 ) Tj ET Q q 0 0 0 rg BT 547.49 276.00 Td (months ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 265.20 Td (\(or) Tj ET Q q 0 0 0 rg BT 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q 0 0 0 rg BT 392.67 265.20 Td (es  ) Tj ET Q /GS0 gs q 9.54 0 0 9.04 404.67 263.26 cm /I7 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 414.21 265.20 Td (  No  ) Tj ET Q /GS0 gs q 8.02 0 0 9.04 434.21 263.26 cm /I8 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 251.40 Td (Indicate ) Tj ET Q q 0 0 0 rg BT 93.06 251.40 Td (by ) Tj ET Q q 0 0 0 rg BT 104.12 251.40 Td (check ) Tj ET Q q 0 0 0 rg BT 127.67 251.40 Td (mark ) Tj ET Q q 0 0 0 rg BT 150.22 251.40 Td (if ) Tj ET Q q 0 0 0 rg BT 157.27 251.40 Td (disclosur) Tj ET Q q 0 0 0 rg BT 191.62 251.40 Td (e ) Tj ET Q q 0 0 0 rg BT 197.17 251.40 Td (of ) Tj ET Q q 0 0 0 rg BT 206.22 251.40 Td (delinquent ) Tj ET Q q 0 0 0 rg BT 248.79 251.40 Td (filers ) Tj ET Q q 0 0 0 rg BT 269.83 251.40 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 306.41 251.40 Td (to ) Tj ET Q q 0 0 0 rg BT 315.46 251.40 Td (Item 405 ) Tj ET Q q 0 0 0 rg BT 350.76 251.40 Td (of ) Tj ET Q q 0 0 0 rg BT 359.81 251.40 Td (Regulation ) Tj ET Q q 0 0 0 rg BT 403.37 251.40 Td (S-K ) Tj ET Q q 0 0 0 rg BT 419.93 251.40 Td (\(§229.405 ) Tj ET Q q 0 0 0 rg BT 458.23 251.40 Td (of ) Tj ET Q q 0 0 0 rg BT 467.28 251.40 Td (this ) Tj ET Q q 0 0 0 rg BT 482.84 251.40 Td (chapter\) ) Tj ET Q q 0 0 0 rg BT 516.89 251.40 Td (is ) Tj ET Q q 0 0 0 rg BT 524.44 251.40 Td (not ) Tj ET Q q 0 0 0 rg BT 538.50 251.40 Td (contained ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 240.60 Td (her) Tj ET Q q 0 0 0 rg BT 48.83 240.60 Td (ein, ) Tj ET Q q 0 0 0 rg BT 65.65 240.60 Td (and ) Tj ET Q q 0 0 0 rg BT 83.22 240.60 Td (will ) Tj ET Q q 0 0 0 rg BT 100.28 240.60 Td (not ) Tj ET Q q 0 0 0 rg BT 115.85 240.60 Td (be ) Tj ET Q q 0 0 0 rg BT 127.91 240.60 Td (contained, ) Tj ET Q q 0 0 0 rg BT 170.73 240.60 Td (to ) Tj ET Q q 0 0 0 rg BT 181.29 240.60 Td (the ) Tj ET Q q 0 0 0 rg BT 196.35 240.60 Td (best ) Tj ET Q q 0 0 0 rg BT 214.91 240.60 Td (of ) Tj ET Q q 0 0 0 rg BT 225.47 240.60 Td (the ) Tj ET Q q 0 0 0 rg BT 240.53 240.60 Td (r) Tj ET Q q 0 0 0 rg BT 244.36 240.60 Td (egistrant’) Tj ET Q q 0 0 0 rg BT 281.02 240.60 Td (s ) Tj ET Q q 0 0 0 rg BT 287.58 240.60 Td (knowledge, ) Tj ET Q q 0 0 0 rg BT 333.90 240.60 Td (in ) Tj ET Q q 0 0 0 rg BT 344.47 240.60 Td (definitive ) Tj ET Q q 0 0 0 rg BT 383.53 240.60 Td (pr) Tj ET Q q 0 0 0 rg BT 392.37 240.60 Td (oxy ) Tj ET Q q 0 0 0 rg BT 408.93 240.60 Td (or) Tj ET Q q 0 0 0 rg BT 417.26 240.60 Td ( ) Tj ET Q q 0 0 0 rg BT 420.32 240.60 Td (information ) Tj ET Q q 0 0 0 rg BT 469.38 240.60 Td (statements ) Tj ET Q q 0 0 0 rg BT 513.44 240.60 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 566.49 240.60 Td (by ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 229.80 Td (r) Tj ET Q q 0 0 0 rg BT 39.83 229.80 Td (efer) Tj ET Q q 0 0 0 rg BT 54.65 229.80 Td (ence ) Tj ET Q q 0 0 0 rg BT 73.89 229.80 Td (in ) Tj ET Q q 0 0 0 rg BT 83.65 229.80 Td (Part ) Tj ET Q q 0 0 0 rg BT 102.88 229.80 Td (III ) Tj ET Q q 0 0 0 rg BT 115.64 229.80 Td (of ) Tj ET Q q 0 0 0 rg BT 125.39 229.80 Td (this ) Tj ET Q q 0 0 0 rg BT 141.64 229.80 Td (Form ) Tj ET Q q 0 0 0 rg BT 165.38 229.80 Td (10-K ) Tj ET Q q 0 0 0 rg BT 186.63 229.80 Td (or) Tj ET Q q 0 0 0 rg BT 194.96 229.80 Td ( ) Tj ET Q q 0 0 0 rg BT 197.21 229.80 Td (any ) Tj ET Q q 0 0 0 rg BT 213.47 229.80 Td (amendment ) Tj ET Q q 0 0 0 rg BT 261.22 229.80 Td (to ) Tj ET Q q 0 0 0 rg BT 270.96 229.80 Td (this ) Tj ET Q q 0 0 0 rg BT 287.22 229.80 Td (Form ) Tj ET Q q 0 0 0 rg BT 310.96 229.80 Td (10-K.  ) Tj ET Q /GS0 gs q 8.02 0 0 9.04 336.70 227.86 cm /I9 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 216.00 Td (Indicate ) Tj ET Q q 0 0 0 rg BT 92.97 216.00 Td (by ) Tj ET Q q 0 0 0 rg BT 103.94 216.00 Td (check ) Tj ET Q q 0 0 0 rg BT 127.40 216.00 Td (mark ) Tj ET Q q 0 0 0 rg BT 149.86 216.00 Td (whether) Tj ET Q q 0 0 0 rg BT 181.19 216.00 Td ( ) Tj ET Q q 0 0 0 rg BT 182.66 216.00 Td (the ) Tj ET Q q 0 0 0 rg BT 196.12 216.00 Td (r) Tj ET Q q 0 0 0 rg BT 199.96 216.00 Td (egistrant ) Tj ET Q q 0 0 0 rg BT 235.41 216.00 Td (is ) Tj ET Q q 0 0 0 rg BT 242.88 216.00 Td (a ) Tj ET Q q 0 0 0 rg BT 248.85 216.00 Td (large ) Tj ET Q q 0 0 0 rg BT 269.81 216.00 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 314.74 216.00 Td (filer) Tj ET Q q 0 0 0 rg BT 329.91 216.00 Td (, ) Tj ET Q q 0 0 0 rg BT 333.62 216.00 Td (an ) Tj ET Q q 0 0 0 rg BT 344.59 216.00 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 389.53 216.00 Td (filer) Tj ET Q q 0 0 0 rg BT 404.69 216.00 Td (, ) Tj ET Q q 0 0 0 rg BT 408.41 216.00 Td (a ) Tj ET Q q 0 0 0 rg BT 414.38 216.00 Td (non-accelerated ) Tj ET Q q 0 0 0 rg BT 476.82 216.00 Td (filer) Tj ET Q q 0 0 0 rg BT 492.65 216.00 Td ( ) Tj ET Q q 0 0 0 rg BT 494.11 216.00 Td (or) Tj ET Q q 0 0 0 rg BT 502.45 216.00 Td ( ) Tj ET Q q 0 0 0 rg BT 503.91 216.00 Td (a ) Tj ET Q q 0 0 0 rg BT 509.88 216.00 Td (smaller) Tj ET Q q 0 0 0 rg BT 538.21 216.00 Td ( ) Tj ET Q q 0 0 0 rg BT 539.67 216.00 Td (r) Tj ET Q q 0 0 0 rg BT 543.51 216.00 Td (eporting ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 205.20 Td (company) Tj ET Q q 0 0 0 rg BT 70.51 205.20 Td (. ) Tj ET Q q 0 0 0 rg BT 74.92 205.20 Td (See ) Tj ET Q q 0 0 0 rg BT 90.08 205.20 Td (definitions ) Tj ET Q q 0 0 0 rg BT 132.76 205.20 Td (of ) Tj ET Q q 0 0 0 rg BT 142.42 205.20 Td (“large ) Tj ET Q q 0 0 0 rg BT 168.58 205.20 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 214.22 205.20 Td (filer”, ) Tj ET Q q 0 0 0 rg BT 239.12 205.20 Td (“accelerated ) Tj ET Q q 0 0 0 rg BT 289.26 205.20 Td (filer” ) Tj ET Q q 0 0 0 rg BT 311.91 205.20 Td (and ) Tj ET Q q 0 0 0 rg BT 328.59 205.20 Td (“smaller) Tj ET Q q 0 0 0 rg BT 361.42 205.20 Td ( ) Tj ET Q q 0 0 0 rg BT 363.58 205.20 Td (r) Tj ET Q q 0 0 0 rg BT 367.41 205.20 Td (eporting ) Tj ET Q q 0 0 0 rg BT 402.08 205.20 Td (company” ) Tj ET Q q 0 0 0 rg BT 443.75 205.20 Td (in ) Tj ET Q q 0 0 0 rg BT 453.42 205.20 Td (Rule ) Tj ET Q q 0 0 0 rg BT 473.59 205.20 Td (12b-2 ) Tj ET Q q 0 0 0 rg BT 497.25 205.20 Td (of ) Tj ET Q q 0 0 0 rg BT 506.92 205.20 Td (the ) Tj ET Q q 0 0 0 rg BT 521.08 205.20 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 560.27 205.20 Td (Act. ) Tj ET Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 39.00 186.11 Td (Large accelerated filer) Tj ET Q q 0 0 0 rg BT 122.90 186.11 Td (  ) Tj ET Q /GS0 gs q 9.22 0 0 8.77 127.25 184.23 cm /I10 Do Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 144.00 186.11 Td (  ) Tj ET Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 148.00 186.11 Td (Accelerated filer) Tj ET Q q 0 0 0 rg BT 209.43 186.11 Td (  ) Tj ET Q /GS0 gs q 7.75 0 0 8.77 213.78 184.23 cm /I11 Do Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 229.00 186.11 Td (  ) Tj ET Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 233.00 186.11 Td (Non-accelerated ) Tj ET Q q 0 0 0 rg BT 295.57 186.11 Td (filer) Tj ET Q q 0 0 0 rg BT 310.86 186.11 Td (  ) Tj ET Q /GS0 gs q 7.75 0 0 8.77 315.21 184.23 cm /I12 Do Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 329.00 186.11 Td (  ) Tj ET Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 333.00 186.11 Td (Smaller) Tj ET Q q 0 0 0 rg BT 361.84 186.11 Td ( r) Tj ET Q q 0 0 0 rg BT 367.72 186.11 Td (eporting company  ) Tj ET Q /GS0 gs q 7.75 0 0 8.77 439.49 184.23 cm /I13 Do Q BT /F2 8.70 Tf ET q 0 0 0 rg BT 459.00 186.11 Td (Emerging gr) Tj ET Q q 0 0 0 rg BT 505.96 186.11 Td (owth company  ) Tj ET Q /GS0 gs q 7.75 0 0 8.77 564.69 184.23 cm /I14 Do Q BT /F1 10.00 Tf ET BT /F2 9.00 Tf ET q 0 0 0 rg BT 58.50 168.40 Td (If ) Tj ET Q q 0 0 0 rg BT 66.40 168.40 Td (an ) Tj ET Q q 0 0 0 rg BT 77.30 168.40 Td (emerging ) Tj ET Q q 0 0 0 rg BT 114.69 168.40 Td (gr) Tj ET Q q 0 0 0 rg BT 123.02 168.40 Td (owth ) Tj ET Q q 0 0 0 rg BT 143.43 168.40 Td (company) Tj ET Q q 0 0 0 rg BT 177.93 168.40 Td (, ) Tj ET Q q 0 0 0 rg BT 181.58 168.40 Td (indicate ) Tj ET Q q 0 0 0 rg BT 213.48 168.40 Td (by ) Tj ET Q q 0 0 0 rg BT 224.38 168.40 Td (check ) Tj ET Q q 0 0 0 rg BT 247.78 168.40 Td (mark ) Tj ET Q q 0 0 0 rg BT 270.18 168.40 Td (if ) Tj ET Q q 0 0 0 rg BT 277.07 168.40 Td (the ) Tj ET Q q 0 0 0 rg BT 290.47 168.40 Td (r) Tj ET Q q 0 0 0 rg BT 294.30 168.40 Td (egistrant ) Tj ET Q q 0 0 0 rg BT 329.69 168.40 Td (has ) Tj ET Q q 0 0 0 rg BT 344.10 168.40 Td (elected ) Tj ET Q q 0 0 0 rg BT 371.98 168.40 Td (not ) Tj ET Q q 0 0 0 rg BT 385.89 168.40 Td (to ) Tj ET Q q 0 0 0 rg BT 394.78 168.40 Td (use ) Tj ET Q q 0 0 0 rg BT 408.68 168.40 Td (the ) Tj ET Q q 0 0 0 rg BT 422.08 168.40 Td (extended ) Tj ET Q q 0 0 0 rg BT 457.98 168.40 Td (transition ) Tj ET Q q 0 0 0 rg BT 496.88 168.40 Td (period ) Tj ET Q q 0 0 0 rg BT 523.28 168.40 Td (for) Tj ET Q q 0 0 0 rg BT 534.61 168.40 Td ( ) Tj ET Q q 0 0 0 rg BT 536.01 168.40 Td (complying ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 156.40 Td (with ) Tj ET Q q 0 0 0 rg BT 55.25 156.40 Td (any ) Tj ET Q q 0 0 0 rg BT 71.51 156.40 Td (new ) Tj ET Q q 0 0 0 rg BT 89.26 156.40 Td (or) Tj ET Q q 0 0 0 rg BT 97.59 156.40 Td ( ) Tj ET Q q 0 0 0 rg BT 99.84 156.40 Td (r) Tj ET Q q 0 0 0 rg BT 103.67 156.40 Td (evised ) Tj ET Q q 0 0 0 rg BT 129.42 156.40 Td (financial ) Tj ET Q q 0 0 0 rg BT 165.17 156.40 Td (accounting ) Tj ET Q q 0 0 0 rg BT 209.43 156.40 Td (standards ) Tj ET Q q 0 0 0 rg BT 249.69 156.40 Td (pr) Tj ET Q q 0 0 0 rg BT 258.53 156.40 Td (ovided ) Tj ET Q q 0 0 0 rg BT 286.28 156.40 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 323.55 156.40 Td (to ) Tj ET Q q 0 0 0 rg BT 333.29 156.40 Td (Section ) Tj ET Q q 0 0 0 rg BT 363.54 156.40 Td (13\(a\) ) Tj ET Q q 0 0 0 rg BT 385.29 156.40 Td (of ) Tj ET Q q 0 0 0 rg BT 395.03 156.40 Td (the ) Tj ET Q q 0 0 0 rg BT 409.28 156.40 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 448.54 156.40 Td (Act. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.53 156.40 Td ( ) Tj ET Q /GS0 gs q 8.91 0 0 10.09 469.03 154.24 cm /I15 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 142.60 Td (Indicate ) Tj ET Q q 0 0 0 rg BT 93.75 142.60 Td (by ) Tj ET Q q 0 0 0 rg BT 105.51 142.60 Td (check ) Tj ET Q q 0 0 0 rg BT 129.75 142.60 Td (mark ) Tj ET Q q 0 0 0 rg BT 153.00 142.60 Td (if ) Tj ET Q q 0 0 0 rg BT 160.74 142.60 Td (the ) Tj ET Q q 0 0 0 rg BT 174.99 142.60 Td (r) Tj ET Q q 0 0 0 rg BT 178.82 142.60 Td (egistrant ) Tj ET Q q 0 0 0 rg BT 215.07 142.60 Td (is ) Tj ET Q q 0 0 0 rg BT 223.32 142.60 Td (a ) Tj ET Q q 0 0 0 rg BT 230.07 142.60 Td (shell ) Tj ET Q q 0 0 0 rg BT 249.82 142.60 Td (company ) Tj ET Q q 0 0 0 rg BT 287.07 142.60 Td (\(as ) Tj ET Q q 0 0 0 rg BT 300.32 142.60 Td (defined ) Tj ET Q q 0 0 0 rg BT 331.08 142.60 Td (in ) Tj ET Q q 0 0 0 rg BT 340.83 142.60 Td (Rule ) Tj ET Q q 0 0 0 rg BT 361.08 142.60 Td (12b-2 ) Tj ET Q q 0 0 0 rg BT 384.83 142.60 Td (of ) Tj ET Q q 0 0 0 rg BT 394.58 142.60 Td (the ) Tj ET Q q 0 0 0 rg BT 408.83 142.60 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 448.09 142.60 Td (Act\).    ) Tj ET Q q 0 0 0 rg BT 475.49 142.60 Td (Y) Tj ET Q q 0 0 0 rg BT 480.99 142.60 Td (es  ) Tj ET Q /GS0 gs q 8.02 0 0 9.04 492.99 140.66 cm /I16 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 501.01 142.60 Td (    No  ) Tj ET Q /GS0 gs q 9.54 0 0 9.04 525.51 140.66 cm /I17 Do Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 128.80 Td (The ) Tj ET Q q 0 0 0 rg BT 77.50 128.80 Td (aggr) Tj ET Q q 0 0 0 rg BT 94.84 128.80 Td (egate ) Tj ET Q q 0 0 0 rg BT 117.32 128.80 Td (market ) Tj ET Q q 0 0 0 rg BT 147.81 128.80 Td (value ) Tj ET Q q 0 0 0 rg BT 170.82 128.80 Td (of ) Tj ET Q q 0 0 0 rg BT 180.81 128.80 Td (the ) Tj ET Q q 0 0 0 rg BT 195.31 128.80 Td (1,638,694,099 ) Tj ET Q q 0 0 0 rg BT 249.56 128.80 Td (shar) Tj ET Q q 0 0 0 rg BT 266.40 128.80 Td (es ) Tj ET Q q 0 0 0 rg BT 276.40 128.80 Td (of ) Tj ET Q q 0 0 0 rg BT 286.40 128.80 Td (voting ) Tj ET Q q 0 0 0 rg BT 312.91 128.80 Td (common ) Tj ET Q q 0 0 0 rg BT 348.40 128.80 Td (equity ) Tj ET Q q 0 0 0 rg BT 374.91 128.80 Td (held ) Tj ET Q q 0 0 0 rg BT 393.91 128.80 Td (by ) Tj ET Q q 0 0 0 rg BT 405.92 128.80 Td (non-affiliates ) Tj ET Q q 0 0 0 rg BT 458.92 128.80 Td (of ) Tj ET Q q 0 0 0 rg BT 468.92 128.80 Td (the ) Tj ET Q q 0 0 0 rg BT 483.42 128.80 Td (r) Tj ET Q q 0 0 0 rg BT 487.25 128.80 Td (egistrant, ) Tj ET Q q 0 0 0 rg BT 525.99 128.80 Td (computed ) Tj ET Q q 0 0 0 rg BT 566.49 128.80 Td (by ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 118.00 Td (r) Tj ET Q q 0 0 0 rg BT 39.83 118.00 Td (efer) Tj ET Q q 0 0 0 rg BT 54.65 118.00 Td (ence ) Tj ET Q q 0 0 0 rg BT 73.30 118.00 Td (to ) Tj ET Q q 0 0 0 rg BT 82.45 118.00 Td (the ) Tj ET Q q 0 0 0 rg BT 96.10 118.00 Td (closing ) Tj ET Q q 0 0 0 rg BT 124.26 118.00 Td (price ) Tj ET Q q 0 0 0 rg BT 145.41 118.00 Td (as ) Tj ET Q q 0 0 0 rg BT 155.06 118.00 Td (r) Tj ET Q q 0 0 0 rg BT 158.90 118.00 Td (eported ) Tj ET Q q 0 0 0 rg BT 190.04 118.00 Td (on ) Tj ET Q q 0 0 0 rg BT 201.20 118.00 Td (the ) Tj ET Q q 0 0 0 rg BT 214.86 118.00 Td (New ) Tj ET Q q 0 0 0 rg BT 233.26 118.00 Td (Y) Tj ET Q q 0 0 0 rg BT 238.76 118.00 Td (ork ) Tj ET Q q 0 0 0 rg BT 253.92 118.00 Td (Stock ) Tj ET Q q 0 0 0 rg BT 277.08 118.00 Td (Exchange, ) Tj ET Q q 0 0 0 rg BT 318.49 118.00 Td (as ) Tj ET Q q 0 0 0 rg BT 328.14 118.00 Td (of ) Tj ET Q q 0 0 0 rg BT 337.30 118.00 Td (the ) Tj ET Q q 0 0 0 rg BT 350.95 118.00 Td (last ) Tj ET Q q 0 0 0 rg BT 366.10 118.00 Td (business ) Tj ET Q q 0 0 0 rg BT 399.78 118.00 Td (day ) Tj ET Q q 0 0 0 rg BT 415.44 118.00 Td (of ) Tj ET Q q 0 0 0 rg BT 424.59 118.00 Td (the ) Tj ET Q q 0 0 0 rg BT 438.25 118.00 Td (r) Tj ET Q q 0 0 0 rg BT 442.08 118.00 Td (egistrant’) Tj ET Q q 0 0 0 rg BT 478.73 118.00 Td (s ) Tj ET Q q 0 0 0 rg BT 483.89 118.00 Td (most ) Tj ET Q q 0 0 0 rg BT 504.04 118.00 Td (r) Tj ET Q q 0 0 0 rg BT 507.88 118.00 Td (ecently ) Tj ET Q q 0 0 0 rg BT 536.52 118.00 Td (completed ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 107.20 Td (second ) Tj ET Q q 0 0 0 rg BT 66.08 107.20 Td (fiscal ) Tj ET Q q 0 0 0 rg BT 90.15 107.20 Td (quarter) Tj ET Q q 0 0 0 rg BT 119.48 107.20 Td ( ) Tj ET Q q 0 0 0 rg BT 123.55 107.20 Td (\(June ) Tj ET Q q 0 0 0 rg BT 149.13 107.20 Td (30, ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 164.46 107.20 Td (2017) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 182.46 107.20 Td (\) ) Tj ET Q q 0 0 0 rg BT 189.53 107.20 Td (was ) Tj ET Q q 0 0 0 rg BT 208.11 107.20 Td (appr) Tj ET Q q 0 0 0 rg BT 226.45 107.20 Td (oximately ) Tj ET Q q 0 0 0 rg BT 268.02 107.20 Td ($91,308,035,210. ) Tj ET Q q 0 0 0 rg BT 335.09 107.20 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 392.65 107.20 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 424.25 107.20 Td (has ) Tj ET Q q 0 0 0 rg BT 441.34 107.20 Td (no ) Tj ET Q q 0 0 0 rg BT 454.92 107.20 Td (non-voting ) Tj ET Q q 0 0 0 rg BT 500.50 107.20 Td (common ) Tj ET Q q 0 0 0 rg BT 537.57 107.20 Td (equity) Tj ET Q q 0 0 0 rg BT 561.08 107.20 Td (. ) Tj ET Q q 0 0 0 rg BT 566.51 107.20 Td (At ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 96.40 Td (February 1, ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 83.74 96.40 Td (2018) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 101.74 96.40 Td (, ) Tj ET Q q 0 0 0 rg BT 106.24 96.40 Td (ther) Tj ET Q q 0 0 0 rg BT 122.07 96.40 Td (e ) Tj ET Q q 0 0 0 rg BT 128.32 96.40 Td (wer) Tj ET Q q 0 0 0 rg BT 142.64 96.40 Td (e ) Tj ET Q q 0 0 0 rg BT 148.89 96.40 Td (1,632,582,502 ) Tj ET Q q 0 0 0 rg BT 202.89 96.40 Td (shar) Tj ET Q q 0 0 0 rg BT 219.73 96.40 Td (es ) Tj ET Q q 0 0 0 rg BT 229.47 96.40 Td (of ) Tj ET Q q 0 0 0 rg BT 239.22 96.40 Td (common ) Tj ET Q q 0 0 0 rg BT 274.46 96.40 Td (stock ) Tj ET Q q 0 0 0 rg BT 296.71 96.40 Td (outstanding.) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 60.00 80.60 Td (DOCUMENTS ) Tj ET Q q 0 0 0 rg BT 123.21 80.60 Td (INCORPORA) Tj ET Q q 0 0 0 rg BT 178.04 80.60 Td (TED ) Tj ET Q q 0 0 0 rg BT 201.25 80.60 Td (BY) Tj ET Q q 0 0 0 rg BT 213.42 80.60 Td ( ) Tj ET Q q 0 0 0 rg BT 218.13 80.60 Td (REFERENCE: ) Tj ET Q q 0 0 0 rg BT 281.34 80.60 Td (Portions ) Tj ET Q q 0 0 0 rg BT 318.55 80.60 Td (of ) Tj ET Q q 0 0 0 rg BT 330.75 80.60 Td (the ) Tj ET Q q 0 0 0 rg BT 347.45 80.60 Td (Pr) Tj ET Q q 0 0 0 rg BT 356.78 80.60 Td (oxy ) Tj ET Q q 0 0 0 rg BT 374.99 80.60 Td (Statement ) Tj ET Q q 0 0 0 rg BT 418.69 80.60 Td (for) Tj ET Q q 0 0 0 rg BT 430.02 80.60 Td ( ) Tj ET Q q 0 0 0 rg BT 434.72 80.60 Td (the ) Tj ET Q q 0 0 0 rg BT 451.43 80.60 Td (r) Tj ET Q q 0 0 0 rg BT 455.26 80.60 Td (egistrant’) Tj ET Q q 0 0 0 rg BT 491.91 80.60 Td (s ) Tj ET Q q 0 0 0 rg BT 499.08 80.60 Td (Annual ) Tj ET Q q 0 0 0 rg BT 532.31 80.60 Td (Meeting ) Tj ET Q q 0 0 0 rg BT 568.50 80.60 Td (of ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 69.80 Td (Stockholders ) Tj ET Q q 0 0 0 rg BT 88.48 69.80 Td (to ) Tj ET Q q 0 0 0 rg BT 98.46 69.80 Td (be ) Tj ET Q q 0 0 0 rg BT 109.93 69.80 Td (held ) Tj ET Q q 0 0 0 rg BT 128.91 69.80 Td (May 1, ) Tj ET Q q 0 0 0 rg BT 157.89 69.80 Td (2018, ) Tj ET Q q 0 0 0 rg BT 180.61 69.80 Td (to ) Tj ET Q q 0 0 0 rg BT 190.59 69.80 Td (be ) Tj ET Q q 0 0 0 rg BT 202.06 69.80 Td (filed ) Tj ET Q q 0 0 0 rg BT 221.54 69.80 Td (within ) Tj ET Q q 0 0 0 rg BT 248.52 69.80 Td (120 ) Tj ET Q q 0 0 0 rg BT 264.50 69.80 Td (days ) Tj ET Q q 0 0 0 rg BT 284.48 69.80 Td (after) Tj ET Q q 0 0 0 rg BT 302.80 69.80 Td ( ) Tj ET Q q 0 0 0 rg BT 305.28 69.80 Td (the ) Tj ET Q q 0 0 0 rg BT 319.75 69.80 Td (conclusion ) Tj ET Q q 0 0 0 rg BT 362.74 69.80 Td (of ) Tj ET Q q 0 0 0 rg BT 372.71 69.80 Td (the ) Tj ET Q q 0 0 0 rg BT 387.19 69.80 Td (r) Tj ET Q q 0 0 0 rg BT 391.02 69.80 Td (egistrant's ) Tj ET Q q 0 0 0 rg BT 433.49 69.80 Td (fiscal ) Tj ET Q q 0 0 0 rg BT 455.96 69.80 Td (year) Tj ET Q q 0 0 0 rg BT 472.79 69.80 Td ( ) Tj ET Q q 0 0 0 rg BT 475.26 69.80 Td (ended ) Tj ET Q q 0 0 0 rg BT 500.75 69.80 Td (December) Tj ET Q q 0 0 0 rg BT 539.56 69.80 Td ( ) Tj ET Q q 0 0 0 rg BT 542.04 69.80 Td (31, ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 555.76 69.80 Td (2017) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 573.76 69.80 Td (, ) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 36.00 59.00 Td (ar) Tj ET Q q 0 0 0 rg BT 44.33 59.00 Td (e ) Tj ET Q q 0 0 0 rg BT 50.58 59.00 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 102.82 59.00 Td (by ) Tj ET Q q 0 0 0 rg BT 114.57 59.00 Td (r) Tj ET Q q 0 0 0 rg BT 118.41 59.00 Td (efer) Tj ET Q q 0 0 0 rg BT 133.22 59.00 Td (ence ) Tj ET Q q 0 0 0 rg BT 152.46 59.00 Td (into ) Tj ET Q q 0 0 0 rg BT 169.72 59.00 Td (Part III ) Tj ET Q q 0 0 0 rg BT 201.71 59.00 Td (of ) Tj ET Q q 0 0 0 rg BT 211.46 59.00 Td (this ) Tj ET Q q 0 0 0 rg BT 227.22 59.00 Td (Annual ) Tj ET Q q 0 0 0 rg BT 257.99 59.00 Td (Report ) Tj ET Q q 0 0 0 rg BT 287.23 59.00 Td (on ) Tj ET Q q 0 0 0 rg BT 298.98 59.00 Td (Form 10-K.) Tj ET Q 0 0 0 RG /GS0 gs 2.50 w 0 i [] 0 d 0 J 0 j 3 M 35.5 45.5 m 575.5 45.5 l s 0 0 0 RG /GS0 gs 2.50 w 0 i [] 0 d 0 J 0 j 3 M 35.5 41.5 m 575.5 41.5 l s BT /F1 10.00 Tf ET endstream endobj 5 0 obj <><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><>] /Rotate 0 /Contents 6 0 R>> endobj 6 0 obj <> stream BT /F2 10.00 Tf ET q 0 0 0 rg BT 217.15 749.25 Td (BRIST) Tj ET Q q 0 0 0 rg BT 246.98 749.25 Td (OL-MYERS SQUIBB COMP) Tj ET Q q 0 0 0 rg BT 373.47 749.25 Td (ANY) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 253.25 737.25 Td (INDEX ) Tj ET Q q 0 0 0 rg BT 287.80 737.25 Td (T) Tj ET Q q 0 0 0 rg BT 294.29 737.25 Td (O FORM 10-K) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 258.35 725.25 Td (DECEMBER 31, 2017) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 353.63 725.25 Td ( ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 680.0333984375 m 68.6923828125 680.0333984375 l s q 0 0 1 rg BT 39.00 681.37 Td (P) Tj ET Q q 0 0 1 rg BT 43.64 681.37 Td (AR) Tj ET Q q 0 0 1 rg BT 56.93 681.37 Td (T) Tj ET Q q 0 0 1 rg BT 62.86 681.37 Td ( I) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 668.0333984375 m 115.3251953125 668.0333984375 l s q 0 0 1 rg BT 87.00 669.37 Td (Item 1.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 668.0333984375 m 164.5615234375 668.0333984375 l s q 0 0 1 rg BT 129.00 669.37 Td (Business) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 656.0333984375 m 247.3203125 656.0333984375 l s q 0 0 1 rg BT 129.00 657.37 Td (Acquisitions and Divestitures) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 644.0333984375 m 349.5126953125 644.0333984375 l s q 0 0 1 rg BT 129.00 645.37 Td (Products, Intellectual Property and Product Exclusivity) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 632.0333984375 m 238.9560546875 632.0333984375 l s q 0 0 1 rg BT 129.00 633.37 Td (Research and Development) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 620.0333984375 m 166.763671875 620.0333984375 l s q 0 0 1 rg BT 129.00 621.37 Td (Alliances) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 608.0333984375 m 286.20703125 608.0333984375 l s q 0 0 1 rg BT 129.00 609.37 Td (Marketing, Distribution and Customers) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 596.0333984375 m 179 596.0333984375 l s q 0 0 1 rg BT 129.00 597.37 Td (Competition) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 584.0333984375 m 310.07421875 584.0333984375 l s q 0 0 1 rg BT 129.00 585.37 Td (Pricing, Price Constraints and Market ) Tj ET Q q 0 0 1 rg BT 281.75 585.37 Td (Access) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 572.0333984375 m 225.3671875 572.0333984375 l s q 0 0 1 rg BT 129.00 573.37 Td (Government Regulation) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 560.0333984375 m 298.4970703125 560.0333984375 l s q 0 0 1 rg BT 129.00 561.37 Td (Sources and ) Tj ET Q q 0 0 1 rg BT 179.55 561.37 Td (A) Tj ET Q q 0 0 1 rg BT 186.03 561.37 Td (vailability of Raw Materials) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 548.0333984375 m 281.4560546875 548.0333984375 l s q 0 0 1 rg BT 129.00 549.37 Td (Manufacturing and Quality ) Tj ET Q q 0 0 1 rg BT 239.81 549.37 Td (Assurance) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 536.0333984375 m 234.810546875 536.0333984375 l s q 0 0 1 rg BT 129.00 537.37 Td (Environmental Regulation) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 524.0333984375 m 173.43359375 524.0333984375 l s q 0 0 1 rg BT 129.00 525.37 Td (Employees) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 512.0333984375 m 206.4853515625 512.0333984375 l s q 0 0 1 rg BT 129.00 513.37 Td (Foreign Operations) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 500.0333984375 m 250.23046875 500.0333984375 l s q 0 0 1 rg BT 129.00 501.37 Td (Bristol-Myers Squibb ) Tj ET Q q 0 0 1 rg BT 218.27 501.37 Td (W) Tj ET Q q 0 0 1 rg BT 226.91 501.37 Td (ebsite) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 488.0333984375 m 122.546875 488.0333984375 l s q 0 0 1 rg BT 87.00 489.37 Td (Item 1A.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 488.0333984375 m 179.2783203125 488.0333984375 l s q 0 0 1 rg BT 129.00 489.37 Td (Risk Factors) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 476.0333984375 m 121.9951171875 476.0333984375 l s q 0 0 1 rg BT 87.00 477.37 Td (Item 1B.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 476.0333984375 m 242.69140625 476.0333984375 l s q 0 0 1 rg BT 129.00 477.37 Td (Unresolved Staf) Tj ET Q q 0 0 1 rg BT 193.53 477.37 Td (f Comments) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 464.0333984375 m 115.3251953125 464.0333984375 l s q 0 0 1 rg BT 87.00 465.37 Td (Item 2.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 464.0333984375 m 169.546875 464.0333984375 l s q 0 0 1 rg BT 129.00 465.37 Td (Properties) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 452.0333984375 m 115.3251953125 452.0333984375 l s q 0 0 1 rg BT 87.00 453.37 Td (Item 3.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 452.0333984375 m 203.140625 452.0333984375 l s q 0 0 1 rg BT 129.00 453.37 Td (Legal Proceedings) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 440.0333984375 m 115.3251953125 440.0333984375 l s q 0 0 1 rg BT 87.00 441.37 Td (Item 4.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 440.0333984375 m 227.3154296875 440.0333984375 l s q 0 0 1 rg BT 129.00 441.37 Td (Mine Safety Disclosures) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 416.0333984375 m 75.63818359375 416.0333984375 l s q 0 0 1 rg BT 39.00 417.37 Td (P) Tj ET Q q 0 0 1 rg BT 43.64 417.37 Td (AR) Tj ET Q q 0 0 1 rg BT 56.93 417.37 Td (T) Tj ET Q q 0 0 1 rg BT 62.86 417.37 Td ( IA) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 416.0333984375 m 273.208984375 416.0333984375 l s q 0 0 1 rg BT 129.00 417.37 Td (Executive Of) Tj ET Q q 0 0 1 rg BT 181.85 417.37 Td (ficers of the Registrant) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 392.0333984375 m 72.0224609375 392.0333984375 l s q 0 0 1 rg BT 39.00 393.37 Td (P) Tj ET Q q 0 0 1 rg BT 43.64 393.37 Td (AR) Tj ET Q q 0 0 1 rg BT 56.93 393.37 Td (T) Tj ET Q q 0 0 1 rg BT 62.86 393.37 Td ( II) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 380.0333984375 m 115.3251953125 380.0333984375 l s q 0 0 1 rg BT 87.00 381.37 Td (Item 5.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 380.0333984375 m 427.134765625 380.0333984375 l s q 0 0 1 rg BT 129.00 381.37 Td (Market for the Registrant's Common Stock and Other Stockholder Matters) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 368.0333984375 m 115.3251953125 368.0333984375 l s q 0 0 1 rg BT 87.00 369.37 Td (Item 6.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 368.0333984375 m 223.9609375 368.0333984375 l s q 0 0 1 rg BT 129.00 369.37 Td (Selected Financial Data) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 356.0333984375 m 115.3251953125 356.0333984375 l s q 0 0 1 rg BT 87.00 357.37 Td (Item 7.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 356.0333984375 m 486.314453125 356.0333984375 l s q 0 0 1 rg BT 129.00 357.37 Td (Management's Discussion and ) Tj ET Q q 0 0 1 rg BT 252.17 357.37 Td (Analysis of Financial Condition and Results of Operations) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 344.0333984375 m 122.546875 344.0333984375 l s q 0 0 1 rg BT 87.00 345.37 Td (Item 7A.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 344.0333984375 m 370.62109375 344.0333984375 l s q 0 0 1 rg BT 129.00 345.37 Td (Quantitative and Qualitative Disclosures ) Tj ET Q q 0 0 1 rg BT 293.40 345.37 Td (About Market Risk) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 332.0333984375 m 115.3251953125 332.0333984375 l s q 0 0 1 rg BT 87.00 333.37 Td (Item 8.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 332.0333984375 m 313.951171875 332.0333984375 l s q 0 0 1 rg BT 129.00 333.37 Td (Financial Statements and Supplementary Data) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 320.0333984375 m 391.7197265625 320.0333984375 l s q 0 0 1 rg BT 129.00 321.37 Td (Consolidated Statements of Earnings and Comprehensive Income) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 308.0333984375 m 245.083984375 308.0333984375 l s q 0 0 1 rg BT 129.00 309.37 Td (Consolidated Balance Sheets) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 296.0333984375 m 288.4384765625 296.0333984375 l s q 0 0 1 rg BT 129.00 297.37 Td (Consolidated Statements of Cash Flows) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 284.0333984375 m 263.4189453125 284.0333984375 l s q 0 0 1 rg BT 129.00 285.37 Td (Notes to the Financial Statements) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 272.03339843749995 m 115.3251953125 272.03339843749995 l s q 0 0 1 rg BT 87.00 273.37 Td (Item 9.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 272.03339843749995 m 487.8134765625 272.03339843749995 l s q 0 0 1 rg BT 129.00 273.37 Td (Changes in and Disagreements with ) Tj ET Q q 0 0 1 rg BT 274.81 273.37 Td (Accountants on ) Tj ET Q q 0 0 1 rg BT 339.24 273.37 Td (Accounting and Financial Disclosure) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 260.03339843749995 m 122.546875 260.03339843749995 l s q 0 0 1 rg BT 87.00 261.37 Td (Item 9A.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 260.03339843749995 m 227.3154296875 260.03339843749995 l s q 0 0 1 rg BT 129.00 261.37 Td (Controls and Procedures) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 248.03339843749995 m 121.9951171875 248.03339843749995 l s q 0 0 1 rg BT 87.00 249.37 Td (Item 9B.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 248.03339843749995 m 202.0322265625 248.03339843749995 l s q 0 0 1 rg BT 129.00 249.37 Td (Other Information) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 224.03339843749995 m 75.3525390625 224.03339843749995 l s q 0 0 1 rg BT 39.00 225.37 Td (P) Tj ET Q q 0 0 1 rg BT 43.64 225.37 Td (AR) Tj ET Q q 0 0 1 rg BT 56.93 225.37 Td (T) Tj ET Q q 0 0 1 rg BT 62.86 225.37 Td ( III) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 212.03339843749995 m 120.3251953125 212.03339843749995 l s q 0 0 1 rg BT 87.00 213.37 Td (Item 10.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 212.03339843749995 m 329.8544921875 212.03339843749995 l s q 0 0 1 rg BT 129.00 213.37 Td (Directors and Executive Of) Tj ET Q q 0 0 1 rg BT 238.50 213.37 Td (ficers of the Registrant) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 200.03339843749995 m 119.9541015625 200.03339843749995 l s q 0 0 1 rg BT 87.00 201.37 Td (Item 1) Tj ET Q q 0 0 1 rg BT 112.45 201.37 Td (1.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 200.03339843749995 m 229.25390625 200.03339843749995 l s q 0 0 1 rg BT 129.00 201.37 Td (Executive Compensation) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 188.03339843749995 m 120.3251953125 188.03339843749995 l s q 0 0 1 rg BT 87.00 189.37 Td (Item 12.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 188.03339843749995 m 534.15625 188.03339843749995 l s q 0 0 1 rg BT 129.00 189.37 Td (Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 176.03339843749995 m 120.3251953125 176.03339843749995 l s q 0 0 1 rg BT 87.00 177.37 Td (Item 13.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 176.03339843749995 m 318.4189453125 176.03339843749995 l s q 0 0 1 rg BT 129.00 177.37 Td (Certain Relationships and Related ) Tj ET Q q 0 0 1 rg BT 267.68 177.37 Td (T) Tj ET Q q 0 0 1 rg BT 273.43 177.37 Td (ransactions) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 164.03339843749995 m 120.3251953125 164.03339843749995 l s q 0 0 1 rg BT 87.00 165.37 Td (Item 14.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 164.03339843749995 m 180.9384765625 164.03339843749995 l s q 0 0 1 rg BT 129.00 165.37 Td (Auditor Fees) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 140.03339843749995 m 75.82373046875 140.03339843749995 l s q 0 0 1 rg BT 39.00 141.37 Td (P) Tj ET Q q 0 0 1 rg BT 43.64 141.37 Td (AR) Tj ET Q q 0 0 1 rg BT 56.93 141.37 Td (T) Tj ET Q q 0 0 1 rg BT 62.86 141.37 Td ( IV) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 128.03339843749995 m 120.3251953125 128.03339843749995 l s q 0 0 1 rg BT 87.00 129.37 Td (Item 15.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 128.03339843749995 m 300.630859375 128.03339843749995 l s q 0 0 1 rg BT 129.00 129.37 Td (Exhibits and Financial Statement Schedule) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 87 116.03339843749995 m 120.3251953125 116.03339843749995 l s q 0 0 1 rg BT 87.00 117.37 Td (Item 16.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 129 116.03339843749995 m 215.1083984375 116.03339843749995 l s q 0 0 1 rg BT 129.00 117.37 Td (Form 10-K Summary) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 92.03339843749995 m 100.1181640625 92.03339843749995 l s q 0 0 1 rg BT 39.00 93.37 Td (SIGNA) Tj ET Q q 0 0 1 rg BT 68.45 93.37 Td (TURES) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 80.03339843749995 m 212.0908203125 80.03339843749995 l s q 0 0 1 rg BT 39.00 81.37 Td (SUMMAR) Tj ET Q q 0 0 1 rg BT 82.91 81.37 Td (Y) Tj ET Q q 0 0 1 rg BT 89.76 81.37 Td ( OF ) Tj ET Q q 0 0 1 rg BT 106.99 81.37 Td (ABBREVIA) Tj ET Q q 0 0 1 rg BT 156.99 81.37 Td (TED ) Tj ET Q q 0 0 1 rg BT 178.75 81.37 Td (TERMS) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39 68.03339843749995 m 112.4130859375 68.03339843749995 l s q 0 0 1 rg BT 39.00 69.37 Td (EXHIBIT) Tj ET Q q 0 0 1 rg BT 78.81 69.37 Td ( INDEX) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET BT /F1 8.50 Tf ET q 0 0 0 rg BT 36.00 49.85 Td (* ) Tj ET Q q 0 0 0 rg BT 54.00 49.85 Td (Indicates ) Tj ET Q q 0 0 0 rg BT 86.81 49.85 Td (brand ) Tj ET Q q 0 0 0 rg BT 108.28 49.85 Td (names ) Tj ET Q q 0 0 0 rg BT 132.13 49.85 Td (of ) Tj ET Q q 0 0 0 rg BT 141.33 49.85 Td (products ) Tj ET Q q 0 0 0 rg BT 172.73 49.85 Td (which ) Tj ET Q q 0 0 0 rg BT 195.63 49.85 Td (are ) Tj ET Q q 0 0 0 rg BT 208.13 49.85 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 248.02 49.85 Td (not ) Tj ET Q q 0 0 0 rg BT 261.00 49.85 Td (owned ) Tj ET Q q 0 0 0 rg BT 285.79 49.85 Td (by ) Tj ET Q q 0 0 0 rg BT 296.41 49.85 Td (BMS. ) Tj ET Q q 0 0 0 rg BT 318.62 49.85 Td (Specific ) Tj ET Q q 0 0 0 rg BT 348.60 49.85 Td (trademark ) Tj ET Q q 0 0 0 rg BT 385.17 49.85 Td (ownership ) Tj ET Q q 0 0 0 rg BT 422.71 49.85 Td (information ) Tj ET Q q 0 0 0 rg BT 464.97 49.85 Td (is ) Tj ET Q q 0 0 0 rg BT 472.76 49.85 Td (included ) Tj ET Q q 0 0 0 rg BT 504.16 49.85 Td (in ) Tj ET Q q 0 0 0 rg BT 512.89 49.85 Td (the ) Tj ET Q q 0 0 0 rg BT 525.40 49.85 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 552.56 49.85 Td (Index.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 668.0333984375 m 559 668.0333984375 l s q 0 0 1 rg BT 554.00 669.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 656.0333984375 m 559 656.0333984375 l s q 0 0 1 rg BT 554.00 657.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 644.0333984375 m 559 644.0333984375 l s q 0 0 1 rg BT 554.00 645.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 632.0333984375 m 559 632.0333984375 l s q 0 0 1 rg BT 554.00 633.37 Td (8) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 620.0333984375 m 563.62890625 620.0333984375 l s q 0 0 1 rg BT 554.00 621.37 Td (1) Tj ET Q q 0 0 1 rg BT 558.63 621.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 608.0333984375 m 564 608.0333984375 l s q 0 0 1 rg BT 554.00 609.37 Td (12) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 596.0333984375 m 564 596.0333984375 l s q 0 0 1 rg BT 554.00 597.37 Td (12) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 584.0333984375 m 564 584.0333984375 l s q 0 0 1 rg BT 554.00 585.37 Td (13) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 572.0333984375 m 564 572.0333984375 l s q 0 0 1 rg BT 554.00 573.37 Td (14) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 560.0333984375 m 564 560.0333984375 l s q 0 0 1 rg BT 554.00 561.37 Td (16) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 548.0333984375 m 564 548.0333984375 l s q 0 0 1 rg BT 554.00 549.37 Td (16) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 536.0333984375 m 564 536.0333984375 l s q 0 0 1 rg BT 554.00 537.37 Td (17) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 524.0333984375 m 564 524.0333984375 l s q 0 0 1 rg BT 554.00 525.37 Td (17) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 512.0333984375 m 564 512.0333984375 l s q 0 0 1 rg BT 554.00 513.37 Td (17) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 500.0333984375 m 564 500.0333984375 l s q 0 0 1 rg BT 554.00 501.37 Td (17) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 488.0333984375 m 564 488.0333984375 l s q 0 0 1 rg BT 554.00 489.37 Td (19) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 476.0333984375 m 564 476.0333984375 l s q 0 0 1 rg BT 554.00 477.37 Td (25) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 464.0333984375 m 564 464.0333984375 l s q 0 0 1 rg BT 554.00 465.37 Td (25) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 452.0333984375 m 564 452.0333984375 l s q 0 0 1 rg BT 554.00 453.37 Td (25) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 440.0333984375 m 564 440.0333984375 l s q 0 0 1 rg BT 554.00 441.37 Td (25) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 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248.03339843749995 l s q 0 0 1 rg BT 554.00 249.37 Td (104) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 212.03339843749995 m 569 212.03339843749995 l s q 0 0 1 rg BT 554.00 213.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 200.03339843749995 m 569 200.03339843749995 l s q 0 0 1 rg BT 554.00 201.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 188.03339843749995 m 569 188.03339843749995 l s q 0 0 1 rg BT 554.00 189.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 176.03339843749995 m 569 176.03339843749995 l s q 0 0 1 rg BT 554.00 177.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 164.03339843749995 m 569 164.03339843749995 l s q 0 0 1 rg BT 554.00 165.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 128.03339843749995 m 569 128.03339843749995 l s q 0 0 1 rg BT 554.00 129.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 116.03339843749995 m 569 116.03339843749995 l s q 0 0 1 rg BT 554.00 117.37 Td (106) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 92.03339843749995 m 569 92.03339843749995 l s q 0 0 1 rg BT 554.00 93.37 Td (107) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 80.03339843749995 m 569 80.03339843749995 l s q 0 0 1 rg BT 554.00 81.37 Td (108) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 554 68.03339843749995 m 569 68.03339843749995 l s q 0 0 1 rg BT 554.00 69.37 Td (109) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL endstream endobj 7 0 obj <> endobj 8 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (3) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 289.80 749.25 Td (P) Tj ET Q q 0 0 0 rg BT 295.17 749.25 Td (AR) Tj ET Q q 0 0 0 rg BT 309.26 749.25 Td (T) Tj ET Q q 0 0 0 rg BT 315.75 749.25 Td ( I) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 729.48 Td (Item 1.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 729.48 Td (BUSINESS.) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 702.25 Td (General) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 678.25 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 94.27 678.25 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 124.78 678.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 165.83 678.25 Td (was ) Tj ET Q q 0 0 0 rg BT 183.55 678.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 236.25 678.25 Td (under ) Tj ET Q q 0 0 0 rg BT 261.18 678.25 Td (the ) Tj ET Q q 0 0 0 rg BT 275.56 678.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 296.06 678.25 Td (of ) Tj ET Q q 0 0 0 rg BT 306.55 678.25 Td (the ) Tj ET Q q 0 0 0 rg BT 320.94 678.25 Td (State ) Tj ET Q q 0 0 0 rg BT 343.10 678.25 Td (of ) Tj ET Q q 0 0 0 rg BT 353.59 678.25 Td (Delaware ) Tj ET Q q 0 0 0 rg BT 394.06 678.25 Td (in ) Tj ET Q q 0 0 0 rg BT 403.53 678.25 Td (August ) Tj ET Q q 0 0 0 rg BT 434.59 678.25 Td (1933 ) Tj ET Q q 0 0 0 rg BT 456.75 678.25 Td (under ) Tj ET Q q 0 0 0 rg BT 481.69 678.25 Td (the ) Tj ET Q q 0 0 0 rg BT 496.07 678.25 Td (name ) Tj ET Q q 0 0 0 rg BT 519.89 678.25 Td (Bristol-Myers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 666.25 Td (Company) Tj ET Q q 0 0 0 rg BT 74.24 666.25 Td (, ) Tj ET Q q 0 0 0 rg BT 79.76 666.25 Td (as ) Tj ET Q q 0 0 0 rg BT 91.12 666.25 Td (successor ) Tj ET Q q 0 0 0 rg BT 132.46 666.25 Td (to ) Tj ET Q q 0 0 0 rg BT 143.26 666.25 Td (a ) Tj ET Q q 0 0 0 rg BT 150.72 666.25 Td (New ) Tj ET Q q 0 0 0 rg BT 172.18 666.25 Td (Y) Tj ET Q q 0 0 0 rg BT 178.40 666.25 Td (ork ) Tj ET Q q 0 0 0 rg BT 194.76 666.25 Td (business ) Tj ET Q q 0 0 0 rg BT 231.67 666.25 Td (started ) Tj ET Q q 0 0 0 rg BT 261.35 666.25 Td (in ) Tj ET Q q 0 0 0 rg BT 272.15 666.25 Td (1887. ) Tj ET Q q 0 0 0 rg BT 297.68 666.25 Td (In ) Tj ET Q q 0 0 0 rg BT 309.03 666.25 Td (1989, ) Tj ET Q q 0 0 0 rg BT 334.55 666.25 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 393.69 666.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 435.60 666.25 Td (changed ) Tj ET Q q 0 0 0 rg BT 471.94 666.25 Td (its ) Tj ET Q q 0 0 0 rg BT 484.41 666.25 Td (name ) Tj ET Q q 0 0 0 rg BT 509.09 666.25 Td (to ) Tj ET Q q 0 0 0 rg BT 519.89 666.25 Td (Bristol-Myers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 654.25 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 66.17 654.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 106.90 654.25 Td (as ) Tj ET Q q 0 0 0 rg BT 117.06 654.25 Td (a ) Tj ET Q q 0 0 0 rg BT 123.33 654.25 Td (result ) Tj ET Q q 0 0 0 rg BT 147.39 654.25 Td (of ) Tj ET Q q 0 0 0 rg BT 157.55 654.25 Td (a ) Tj ET Q q 0 0 0 rg BT 163.83 654.25 Td (mer) Tj ET Q q 0 0 0 rg BT 179.19 654.25 Td (ger) Tj ET Q q 0 0 0 rg BT 191.41 654.25 Td (. ) Tj ET Q q 0 0 0 rg BT 195.61 654.25 Td (W) Tj ET Q q 0 0 0 rg BT 204.25 654.25 Td (e ) Tj ET Q q 0 0 0 rg BT 210.52 654.25 Td (are ) Tj ET Q q 0 0 0 rg BT 224.56 654.25 Td (engaged ) Tj ET Q q 0 0 0 rg BT 259.71 654.25 Td (in ) Tj ET Q q 0 0 0 rg BT 269.33 654.25 Td (the ) Tj ET Q q 0 0 0 rg BT 283.38 654.25 Td (discovery) Tj ET Q q 0 0 0 rg BT 321.61 654.25 Td (, ) Tj ET Q q 0 0 0 rg BT 325.94 654.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 381.93 654.25 Td (licensing, ) Tj ET Q q 0 0 0 rg BT 422.37 654.25 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 485.01 654.25 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 529.89 654.25 Td (distribution ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 642.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.91 642.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 70.93 642.25 Td (of ) Tj ET Q q 0 0 0 rg BT 81.73 642.25 Td (biopharmaceutical ) Tj ET Q q 0 0 0 rg BT 158.06 642.25 Td (products ) Tj ET Q q 0 0 0 rg BT 194.97 642.25 Td (on ) Tj ET Q q 0 0 0 rg BT 207.44 642.25 Td (a ) Tj ET Q q 0 0 0 rg BT 214.35 642.25 Td (global ) Tj ET Q q 0 0 0 rg BT 241.82 642.25 Td (basis. ) Tj ET Q q 0 0 0 rg BT 266.79 642.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 291.47 642.25 Td (to ) Tj ET Q q 0 0 0 rg BT 301.72 642.25 Td (the ) Tj ET Q q 0 0 0 rg BT 316.41 642.25 Td (Summary ) Tj ET Q q 0 0 0 rg BT 357.77 642.25 Td (of ) Tj ET Q q 0 0 0 rg BT 368.02 642.25 Td (Abbreviated ) Tj ET Q q 0 0 0 rg BT 419.74 642.25 Td (T) Tj ET Q q 0 0 0 rg BT 425.15 642.25 Td (erms ) Tj ET Q q 0 0 0 rg BT 447.06 642.25 Td (at ) Tj ET Q q 0 0 0 rg BT 456.75 642.25 Td (the ) Tj ET Q q 0 0 0 rg BT 471.44 642.25 Td (end ) Tj ET Q q 0 0 0 rg BT 488.35 642.25 Td (of ) Tj ET Q q 0 0 0 rg BT 499.15 642.25 Td (this ) Tj ET Q q 0 0 0 rg BT 516.07 642.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 538.54 642.25 Td (Form ) Tj ET Q q 0 0 0 rg BT 562.69 642.25 Td (10-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 630.25 Td (K ) Tj ET Q q 0 0 0 rg BT 45.72 630.25 Td (for ) Tj ET Q q 0 0 0 rg BT 59.88 630.25 Td (terms ) Tj ET Q q 0 0 0 rg BT 84.60 630.25 Td (used ) Tj ET Q q 0 0 0 rg BT 105.43 630.25 Td (throughout ) Tj ET Q q 0 0 0 rg BT 151.82 630.25 Td (the ) Tj ET Q q 0 0 0 rg BT 166.53 630.25 Td (document.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 606.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 606.25 Td (e ) Tj ET Q q 0 0 0 rg BT 52.97 606.25 Td (operate ) Tj ET Q q 0 0 0 rg BT 86.29 606.25 Td (in ) Tj ET Q q 0 0 0 rg BT 97.97 606.25 Td (one ) Tj ET Q q 0 0 0 rg BT 116.30 606.25 Td (segment—BioPharmaceuticals. ) Tj ET Q q 0 0 0 rg BT 246.00 606.25 Td (For ) Tj ET Q q 0 0 0 rg BT 263.79 606.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 307.67 606.25 Td (information ) Tj ET Q q 0 0 0 rg BT 358.78 606.25 Td (about ) Tj ET Q q 0 0 0 rg BT 384.89 606.25 Td (business ) Tj ET Q q 0 0 0 rg BT 422.68 606.25 Td (segments, ) Tj ET Q q 0 0 0 rg BT 466.29 606.25 Td (refer ) Tj ET Q q 0 0 0 rg BT 489.06 606.25 Td (to ) Tj ET Q q 0 0 0 rg BT 500.73 606.25 Td (“Item ) Tj ET Q q 0 0 0 rg BT 527.39 606.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 538.79 606.25 Td (Financial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 594.25 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 111.82 594.25 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 116.82 594.25 Td (. ) Tj ET Q q 0 0 0 rg BT 121.82 594.25 Td (Business ) Tj ET Q q 0 0 0 rg BT 159.88 594.25 Td (Segment ) Tj ET Q q 0 0 0 rg BT 197.38 594.25 Td (Information.”) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 570.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 570.25 Td (e ) Tj ET Q q 0 0 0 rg BT 52.15 570.25 Td (compete ) Tj ET Q q 0 0 0 rg BT 89.09 570.25 Td (with ) Tj ET Q q 0 0 0 rg BT 109.93 570.25 Td (other ) Tj ET Q q 0 0 0 rg BT 133.55 570.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 179.39 570.25 Td (research-based ) Tj ET Q q 0 0 0 rg BT 241.86 570.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 263.26 570.25 Td (companies, ) Tj ET Q q 0 0 0 rg BT 311.59 570.25 Td (smaller ) Tj ET Q q 0 0 0 rg BT 344.09 570.25 Td (research ) Tj ET Q q 0 0 0 rg BT 380.47 570.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 426.30 570.25 Td (and ) Tj ET Q q 0 0 0 rg BT 443.81 570.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 476.30 570.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 497.70 570.25 Td (manufacturers. ) Tj ET Q q 0 0 0 rg BT 560.46 570.25 Td (Our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 558.25 Td (products ) Tj ET Q q 0 0 0 rg BT 72.82 558.25 Td (are ) Tj ET Q q 0 0 0 rg BT 87.41 558.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 106.46 558.25 Td (worldwide, ) Tj ET Q q 0 0 0 rg BT 154.11 558.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 193.70 558.25 Td (to ) Tj ET Q q 0 0 0 rg BT 203.86 558.25 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 255.94 558.25 Td (retail ) Tj ET Q q 0 0 0 rg BT 278.87 558.25 Td (pharmacies, ) Tj ET Q q 0 0 0 rg BT 329.28 558.25 Td (hospitals, ) Tj ET Q q 0 0 0 rg BT 369.72 558.25 Td (government ) Tj ET Q q 0 0 0 rg BT 419.86 558.25 Td (entities ) Tj ET Q q 0 0 0 rg BT 451.12 558.25 Td (and ) Tj ET Q q 0 0 0 rg BT 467.94 558.25 Td (the ) Tj ET Q q 0 0 0 rg BT 482.54 558.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 516.57 558.25 Td (profession. ) Tj ET Q q 0 0 0 rg BT 562.94 558.25 Td (W) Tj ET Q q 0 0 0 rg BT 571.58 558.25 Td (e ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 546.25 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 88.41 546.25 Td (products ) Tj ET Q q 0 0 0 rg BT 125.29 546.25 Td (in ) Tj ET Q q 0 0 0 rg BT 135.51 546.25 Td (the ) Tj ET Q q 0 0 0 rg BT 150.17 546.25 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 172.89 546.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 201.44 546.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 222.77 546.25 Td (and ) Tj ET Q q 0 0 0 rg BT 239.64 546.25 Td (in ) Tj ET Q q 0 0 0 rg BT 249.86 546.25 Td (four ) Tj ET Q q 0 0 0 rg BT 268.96 546.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 300.28 546.25 Td (countries. ) Tj ET Q q 0 0 0 rg BT 341.88 546.25 Td (Most ) Tj ET Q q 0 0 0 rg BT 364.88 546.25 Td (of ) Tj ET Q q 0 0 0 rg BT 375.65 546.25 Td (our ) Tj ET Q q 0 0 0 rg BT 391.42 546.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 429.40 546.25 Td (come ) Tj ET Q q 0 0 0 rg BT 453.49 546.25 Td (from ) Tj ET Q q 0 0 0 rg BT 475.37 546.25 Td (products ) Tj ET Q q 0 0 0 rg BT 512.25 546.25 Td (in ) Tj ET Q q 0 0 0 rg BT 522.47 546.25 Td (the ) Tj ET Q q 0 0 0 rg BT 537.13 546.25 Td (following ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 534.25 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 82.92 534.25 Td (classes: ) Tj ET Q q 0 0 0 rg BT 115.97 534.25 Td (oncology; ) Tj ET Q q 0 0 0 rg BT 158.46 534.25 Td (cardiovascular; ) Tj ET Q q 0 0 0 rg BT 222.04 534.25 Td (immunoscience; ) Tj ET Q q 0 0 0 rg BT 290.08 534.25 Td (and ) Tj ET Q q 0 0 0 rg BT 307.02 534.25 Td (virology) Tj ET Q q 0 0 0 rg BT 340.25 534.25 Td (, ) Tj ET Q q 0 0 0 rg BT 345.25 534.25 Td (including ) Tj ET Q q 0 0 0 rg BT 385.53 534.25 Td (HIV) Tj ET Q q 0 0 0 rg BT 403.12 534.25 Td ( ) Tj ET Q q 0 0 0 rg BT 405.62 534.25 Td (infection.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 510.25 Td (The percentage of revenues by significant region/country were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 473.75 318.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 473.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 473.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 473.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 473.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 473.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 473.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 447.75 318.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 447.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 447.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 447.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 447.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 447.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 447.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 421.75 318.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 421.75 4.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 421.75 69.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 421.75 4.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 421.75 69.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 421.75 4.00 -4.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 421.75 70.00 -4.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 358.5 486.75 m 427.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 486.75 m 431.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 486.75 m 500.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 500.5 486.75 m 504.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 504.5 486.75 m 574.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 358.5 486.75 m 427.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 358.5 473.75 m 427.5 473.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 486.75 m 431.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 486.75 m 500.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 473.75 m 500.5 473.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 500.5 486.75 m 504.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 504.5 486.75 m 574.5 486.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 504.5 473.75 m 574.5 473.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 473.75 m 500.5 473.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 504.5 473.75 m 574.5 473.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 491.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 490.98 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 490.98 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 490.98 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 490.98 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 478.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.50 477.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 457.50 477.98 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 531.00 477.98 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 464.32 Td (United States) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 464.32 Td (55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 464.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 464.32 Td (55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.65 464.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.65 464.32 Td (49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 565.65 464.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 451.32 Td (Europe) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 451.32 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 451.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 451.32 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.65 451.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.65 451.32 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 565.65 451.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 438.32 Td (Japan) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 438.32 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 438.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.65 438.32 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.65 438.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.65 438.32 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 565.65 438.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 425.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 425.32 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 425.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 425.32 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.65 425.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.65 425.32 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 565.65 425.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 408.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 408.32 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 361.00 408.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.15 408.32 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 408.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.15 408.32 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.00 408.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 538.15 408.32 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 381.25 Td (Acquisitions ) Tj ET Q q 0 0 0 rg BT 91.29 381.25 Td (and ) Tj ET Q q 0 0 0 rg BT 109.92 381.25 Td (Divestitur) Tj ET Q q 0 0 0 rg BT 152.50 381.25 Td (es) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.25 Td (Acquisitions ) Tj ET Q q 0 0 0 rg BT 89.24 357.25 Td (in ) Tj ET Q q 0 0 0 rg BT 99.70 357.25 Td (the ) Tj ET Q q 0 0 0 rg BT 114.59 357.25 Td (last ) Tj ET Q q 0 0 0 rg BT 131.16 357.25 Td (five ) Tj ET Q q 0 0 0 rg BT 149.39 357.25 Td (years ) Tj ET Q q 0 0 0 rg BT 173.17 357.25 Td (include ) Tj ET Q q 0 0 0 rg BT 205.28 357.25 Td (IFM ) Tj ET Q q 0 0 0 rg BT 225.75 357.25 Td (in ) Tj ET Q q 0 0 0 rg BT 236.21 357.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 261.39 357.25 Td (Cormorant ) Tj ET Q q 0 0 0 rg BT 307.39 357.25 Td (and ) Tj ET Q q 0 0 0 rg BT 324.51 357.25 Td (Padlock ) Tj ET Q q 0 0 0 rg BT 359.41 357.25 Td (in ) Tj ET Q q 0 0 0 rg BT 369.87 357.25 Td (2016, ) Tj ET Q q 0 0 0 rg BT 395.05 357.25 Td (Cardioxyl ) Tj ET Q q 0 0 0 rg BT 437.72 357.25 Td (and ) Tj ET Q q 0 0 0 rg BT 454.84 357.25 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 484.19 357.25 Td (in ) Tj ET Q q 0 0 0 rg BT 494.65 357.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 517.33 357.25 Td (and ) Tj ET Q q 0 0 0 rg BT 534.45 357.25 Td (iPierian ) Tj ET Q q 0 0 0 rg BT 568.24 357.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.25 Td (2014 ) Tj ET Q q 0 0 0 rg BT 58.47 345.25 Td (and ) Tj ET Q q 0 0 0 rg BT 75.37 345.25 Td (we ) Tj ET Q q 0 0 0 rg BT 89.50 345.25 Td (also ) Tj ET Q q 0 0 0 rg BT 108.08 345.25 Td (entered ) Tj ET Q q 0 0 0 rg BT 139.97 345.25 Td (into ) Tj ET Q q 0 0 0 rg BT 157.99 345.25 Td (several ) Tj ET Q q 0 0 0 rg BT 188.77 345.25 Td (license ) Tj ET Q q 0 0 0 rg BT 219.00 345.25 Td (and ) Tj ET Q q 0 0 0 rg BT 235.91 345.25 Td (other ) Tj ET Q q 0 0 0 rg BT 258.92 345.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 314.15 345.25 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 372.98 345.25 Td (Divestitures ) Tj ET Q q 0 0 0 rg BT 423.77 345.25 Td (in ) Tj ET Q q 0 0 0 rg BT 434.02 345.25 Td (the ) Tj ET Q q 0 0 0 rg BT 448.70 345.25 Td (last ) Tj ET Q q 0 0 0 rg BT 465.06 345.25 Td (five ) Tj ET Q q 0 0 0 rg BT 483.07 345.25 Td (years ) Tj ET Q q 0 0 0 rg BT 506.64 345.25 Td (include ) Tj ET Q q 0 0 0 rg BT 538.54 345.25 Td (our ) Tj ET Q q 0 0 0 rg BT 554.33 345.25 Td (small ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.25 Td (molecule ) Tj ET Q q 0 0 0 rg BT 75.73 333.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 137.11 333.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 181.84 333.25 Td (in ) Tj ET Q q 0 0 0 rg BT 192.70 333.25 Td (Swords, ) Tj ET Q q 0 0 0 rg BT 228.28 333.25 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 259.67 333.25 Td (in ) Tj ET Q q 0 0 0 rg BT 270.52 333.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 296.09 333.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 326.37 333.25 Td (OTC ) Tj ET Q q 0 0 0 rg BT 349.45 333.25 Td (brands ) Tj ET Q q 0 0 0 rg BT 379.18 333.25 Td (and ) Tj ET Q q 0 0 0 rg BT 396.70 333.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 458.65 333.25 Td (HIV) Tj ET Q q 0 0 0 rg BT 476.24 333.25 Td ( ) Tj ET Q q 0 0 0 rg BT 479.32 333.25 Td (medicines ) Tj ET Q q 0 0 0 rg BT 522.93 333.25 Td (businesses ) Tj ET Q q 0 0 0 rg BT 568.23 333.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 321.25 Td (2016, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 61.31 321.25 Td (Erbitux* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 99.11 321.25 Td (in ) Tj ET Q q 0 0 0 rg BT 109.70 321.25 Td (North ) Tj ET Q q 0 0 0 rg BT 135.22 321.25 Td (America ) Tj ET Q q 0 0 0 rg BT 172.45 321.25 Td (and ) Tj ET Q q 0 0 0 rg BT 189.70 321.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 219.71 321.25 Td (mature ) Tj ET Q q 0 0 0 rg BT 250.28 321.25 Td (and ) Tj ET Q q 0 0 0 rg BT 267.53 321.25 Td (other ) Tj ET Q q 0 0 0 rg BT 290.89 321.25 Td (OTC ) Tj ET Q q 0 0 0 rg BT 313.70 321.25 Td (brands ) Tj ET Q q 0 0 0 rg BT 343.17 321.25 Td (businesses ) Tj ET Q q 0 0 0 rg BT 388.20 321.25 Td (in ) Tj ET Q q 0 0 0 rg BT 398.78 321.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 421.59 321.25 Td (and ) Tj ET Q q 0 0 0 rg BT 438.84 321.25 Td (our ) Tj ET Q q 0 0 0 rg BT 454.98 321.25 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 490.55 321.25 Td (business ) Tj ET Q q 0 0 0 rg BT 527.25 321.25 Td (in ) Tj ET Q q 0 0 0 rg BT 537.84 321.25 Td (2014. ) Tj ET Q q 0 0 0 rg BT 562.95 321.25 Td (W) Tj ET Q q 0 0 0 rg BT 571.58 321.25 Td (e ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.25 Td (also ) Tj ET Q q 0 0 0 rg BT 55.02 309.25 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 106.81 309.25 Td (our ) Tj ET Q q 0 0 0 rg BT 123.05 309.25 Td (genetically ) Tj ET Q q 0 0 0 rg BT 169.83 309.25 Td (defined ) Tj ET Q q 0 0 0 rg BT 202.73 309.25 Td (disease ) Tj ET Q q 0 0 0 rg BT 234.52 309.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 296.31 309.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 345.33 309.25 Td (in ) Tj ET Q q 0 0 0 rg BT 356.02 309.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 381.22 309.25 Td (These ) Tj ET Q q 0 0 0 rg BT 408.01 309.25 Td (transactions ) Tj ET Q q 0 0 0 rg BT 458.69 309.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 496.03 309.25 Td (to ) Tj ET Q q 0 0 0 rg BT 506.72 309.25 Td (allow ) Tj ET Q q 0 0 0 rg BT 531.85 309.25 Td (us ) Tj ET Q q 0 0 0 rg BT 543.66 309.25 Td (to ) Tj ET Q q 0 0 0 rg BT 554.35 309.25 Td (focus ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.25 Td (our ) Tj ET Q q 0 0 0 rg BT 51.83 297.25 Td (resources ) Tj ET Q q 0 0 0 rg BT 92.09 297.25 Td (behind ) Tj ET Q q 0 0 0 rg BT 121.81 297.25 Td (growth ) Tj ET Q q 0 0 0 rg BT 152.64 297.25 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 207.91 297.25 Td (which ) Tj ET Q q 0 0 0 rg BT 234.85 297.25 Td (drive ) Tj ET Q q 0 0 0 rg BT 257.89 297.25 Td (the ) Tj ET Q q 0 0 0 rg BT 272.61 297.25 Td (greatest ) Tj ET Q q 0 0 0 rg BT 306.21 297.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 348.14 297.25 Td (value.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 273.25 Td (Pr) Tj ET Q q 0 0 0 rg BT 46.37 273.25 Td (oducts, Intellectual Pr) Tj ET Q q 0 0 0 rg BT 140.34 273.25 Td (operty and Pr) Tj ET Q q 0 0 0 rg BT 199.60 273.25 Td (oduct Exclusivity) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 249.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.55 249.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 116.62 249.25 Td (products ) Tj ET Q q 0 0 0 rg BT 153.06 249.25 Td (include ) Tj ET Q q 0 0 0 rg BT 184.49 249.25 Td (chemically-synthesized ) Tj ET Q q 0 0 0 rg BT 280.34 249.25 Td (or ) Tj ET Q q 0 0 0 rg BT 290.66 249.25 Td (small ) Tj ET Q q 0 0 0 rg BT 314.33 249.25 Td (molecule ) Tj ET Q q 0 0 0 rg BT 352.97 249.25 Td (drugs, ) Tj ET Q q 0 0 0 rg BT 379.69 249.25 Td (and ) Tj ET Q q 0 0 0 rg BT 396.13 249.25 Td (products ) Tj ET Q q 0 0 0 rg BT 432.56 249.25 Td (produced ) Tj ET Q q 0 0 0 rg BT 471.77 249.25 Td (from ) Tj ET Q q 0 0 0 rg BT 493.20 249.25 Td (biological ) Tj ET Q q 0 0 0 rg BT 535.19 249.25 Td (processes, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 237.25 Td (called ) Tj ET Q q 0 0 0 rg BT 61.76 237.25 Td (“biologics.” ) Tj ET Q q 0 0 0 rg BT 111.70 237.25 Td (Small ) Tj ET Q q 0 0 0 rg BT 136.92 237.25 Td (molecule ) Tj ET Q q 0 0 0 rg BT 175.46 237.25 Td (drugs ) Tj ET Q q 0 0 0 rg BT 199.58 237.25 Td (are ) Tj ET Q q 0 0 0 rg BT 213.67 237.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 250.56 237.25 Td (administered ) Tj ET Q q 0 0 0 rg BT 304.10 237.25 Td (orally) Tj ET Q q 0 0 0 rg BT 326.77 237.25 Td (, ) Tj ET Q q 0 0 0 rg BT 331.16 237.25 Td (e.g., ) Tj ET Q q 0 0 0 rg BT 349.99 237.25 Td (in ) Tj ET Q q 0 0 0 rg BT 359.66 237.25 Td (the ) Tj ET Q q 0 0 0 rg BT 373.77 237.25 Td (form ) Tj ET Q q 0 0 0 rg BT 395.10 237.25 Td (of ) Tj ET Q q 0 0 0 rg BT 405.32 237.25 Td (a ) Tj ET Q q 0 0 0 rg BT 411.65 237.25 Td (pill ) Tj ET Q q 0 0 0 rg BT 426.88 237.25 Td (or ) Tj ET Q q 0 0 0 rg BT 437.10 237.25 Td (tablet, ) Tj ET Q q 0 0 0 rg BT 463.70 237.25 Td (although ) Tj ET Q q 0 0 0 rg BT 500.59 237.25 Td (other ) Tj ET Q q 0 0 0 rg BT 523.03 237.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 543.25 237.25 Td (delivery ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 225.25 Td (mechanisms ) Tj ET Q q 0 0 0 rg BT 87.93 225.25 Td (are ) Tj ET Q q 0 0 0 rg BT 102.64 225.25 Td (used ) Tj ET Q q 0 0 0 rg BT 123.47 225.25 Td (as ) Tj ET Q q 0 0 0 rg BT 134.30 225.25 Td (well. ) Tj ET Q q 0 0 0 rg BT 156.52 225.25 Td (Biologics ) Tj ET Q q 0 0 0 rg BT 197.35 225.25 Td (are ) Tj ET Q q 0 0 0 rg BT 212.06 225.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 249.55 225.25 Td (administered ) Tj ET Q q 0 0 0 rg BT 303.70 225.25 Td (to ) Tj ET Q q 0 0 0 rg BT 313.98 225.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 347.58 225.25 Td (through ) Tj ET Q q 0 0 0 rg BT 381.19 225.25 Td (injections ) Tj ET Q q 0 0 0 rg BT 422.57 225.25 Td (or ) Tj ET Q q 0 0 0 rg BT 433.40 225.25 Td (by ) Tj ET Q q 0 0 0 rg BT 445.90 225.25 Td (intravenous ) Tj ET Q q 0 0 0 rg BT 495.06 225.25 Td (infusion. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.25 Td (Below ) Tj ET Q q 0 0 0 rg BT 64.90 201.25 Td (is ) Tj ET Q q 0 0 0 rg BT 74.36 201.25 Td (a ) Tj ET Q q 0 0 0 rg BT 81.59 201.25 Td (product ) Tj ET Q q 0 0 0 rg BT 114.93 201.25 Td (summary ) Tj ET Q q 0 0 0 rg BT 154.94 201.25 Td (including ) Tj ET Q q 0 0 0 rg BT 195.51 201.25 Td (approved ) Tj ET Q q 0 0 0 rg BT 235.50 201.25 Td (indications. ) Tj ET Q q 0 0 0 rg BT 284.68 201.25 Td (For ) Tj ET Q q 0 0 0 rg BT 301.36 201.25 Td (information ) Tj ET Q q 0 0 0 rg BT 351.37 201.25 Td (about ) Tj ET Q q 0 0 0 rg BT 376.38 201.25 Td (our ) Tj ET Q q 0 0 0 rg BT 392.50 201.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 426.38 201.25 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 483.03 201.25 Td (for ) Tj ET Q q 0 0 0 rg BT 497.48 201.25 Td (the ) Tj ET Q q 0 0 0 rg BT 512.49 201.25 Td (products ) Tj ET Q q 0 0 0 rg BT 549.72 201.25 Td (below) Tj ET Q q 0 0 0 rg BT 573.51 201.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.25 Td (refer ) Tj ET Q q 0 0 0 rg BT 57.37 189.25 Td (to ) Tj ET Q q 0 0 0 rg BT 67.65 189.25 Td (“—Alliances" ) Tj ET Q q 0 0 0 rg BT 126.43 189.25 Td (below ) Tj ET Q q 0 0 0 rg BT 153.37 189.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.31 189.25 Td ("Item ) Tj ET Q q 0 0 0 rg BT 195.21 189.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 205.21 189.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 244.93 189.25 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.75 189.25 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.75 189.25 Td (. ) Tj ET Q q 0 0 0 rg BT 330.19 189.25 Td (Alliances.”) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 171.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 65.44 171.25 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 171.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.94 171.25 Td (, ) Tj ET Q q 0 0 0 rg BT 164.94 171.25 Td (a ) Tj ET Q q 0 0 0 rg BT 171.88 171.25 Td (biological ) Tj ET Q q 0 0 0 rg BT 214.37 171.25 Td (product, ) Tj ET Q q 0 0 0 rg BT 249.92 171.25 Td (is ) Tj ET Q q 0 0 0 rg BT 259.09 171.25 Td (a ) Tj ET Q q 0 0 0 rg BT 266.03 171.25 Td (fully ) Tj ET Q q 0 0 0 rg BT 287.42 171.25 Td (human ) Tj ET Q q 0 0 0 rg BT 317.14 171.25 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 366.85 171.25 Td (antibody ) Tj ET Q q 0 0 0 rg BT 404.35 171.25 Td (that ) Tj ET Q q 0 0 0 rg BT 421.84 171.25 Td (binds ) Tj ET Q q 0 0 0 rg BT 446.02 171.25 Td (to ) Tj ET Q q 0 0 0 rg BT 456.30 171.25 Td (the ) Tj ET Q q 0 0 0 rg BT 471.01 171.25 Td (PD-1 ) Tj ET Q q 0 0 0 rg BT 494.63 171.25 Td (on ) Tj ET Q q 0 0 0 rg BT 506.95 171.25 Td (T) Tj ET Q q 0 0 0 rg BT 512.88 171.25 Td ( ) Tj ET Q q 0 0 0 rg BT 515.38 171.25 Td (and ) Tj ET Q q 0 0 0 rg BT 532.32 171.25 Td (NKT) Tj ET Q q 0 0 0 rg BT 552.69 171.25 Td ( ) Tj ET Q q 0 0 0 rg BT 555.19 171.25 Td (cells. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 159.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.94 159.25 Td ( ) Tj ET Q q 0 0 0 rg BT 161.88 159.25 Td (has ) Tj ET Q q 0 0 0 rg BT 177.15 159.25 Td (received ) Tj ET Q q 0 0 0 rg BT 212.96 159.25 Td (approvals ) Tj ET Q q 0 0 0 rg BT 253.78 159.25 Td (for ) Tj ET Q q 0 0 0 rg BT 267.38 159.25 Td (several ) Tj ET Q q 0 0 0 rg BT 297.64 159.25 Td (anti-cancer ) Tj ET Q q 0 0 0 rg BT 343.99 159.25 Td (indications ) Tj ET Q q 0 0 0 rg BT 389.81 159.25 Td (including ) Tj ET Q q 0 0 0 rg BT 429.53 159.25 Td (bladder) Tj ET Q q 0 0 0 rg BT 459.11 159.25 Td (, ) Tj ET Q q 0 0 0 rg BT 463.56 159.25 Td (blood, ) Tj ET Q q 0 0 0 rg BT 490.78 159.25 Td (colon, ) Tj ET Q q 0 0 0 rg BT 517.44 159.25 Td (head ) Tj ET Q q 0 0 0 rg BT 538.26 159.25 Td (and ) Tj ET Q q 0 0 0 rg BT 554.64 159.25 Td (neck, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 147.25 Td (kidney) Tj ET Q q 0 0 0 rg BT 157.07 147.25 Td (, ) Tj ET Q q 0 0 0 rg BT 162.50 147.25 Td (liver) Tj ET Q q 0 0 0 rg BT 180.42 147.25 Td (, ) Tj ET Q q 0 0 0 rg BT 185.86 147.25 Td (lung, ) Tj ET Q q 0 0 0 rg BT 209.07 147.25 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 253.65 147.25 Td (and ) Tj ET Q q 0 0 0 rg BT 271.02 147.25 Td (stomach. ) Tj ET Q q 0 0 0 rg BT 309.57 147.25 Td (The ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 328.04 147.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.48 147.25 Td (+) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 363.12 147.25 Td (Y) Tj ET Q q 0 0 0 rg BT 367.77 147.25 Td (ervoy ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.91 147.25 Td (regimen ) Tj ET Q q 0 0 0 rg BT 428.60 147.25 Td (also ) Tj ET Q q 0 0 0 rg BT 447.64 147.25 Td (is ) Tj ET Q q 0 0 0 rg BT 457.24 147.25 Td (approved ) Tj ET Q q 0 0 0 rg BT 497.38 147.25 Td (in ) Tj ET Q q 0 0 0 rg BT 508.09 147.25 Td (multiple ) Tj ET Q q 0 0 0 rg BT 544.36 147.25 Td (markets ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 135.25 Td (for ) Tj ET Q q 0 0 0 rg BT 145.42 135.25 Td (the ) Tj ET Q q 0 0 0 rg BT 160.89 135.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 201.91 135.25 Td (of ) Tj ET Q q 0 0 0 rg BT 213.50 135.25 Td (melanoma. ) Tj ET Q q 0 0 0 rg BT 260.67 135.25 Td (There ) Tj ET Q q 0 0 0 rg BT 287.25 135.25 Td (are ) Tj ET Q q 0 0 0 rg BT 302.71 135.25 Td (several ) Tj ET Q q 0 0 0 rg BT 334.28 135.25 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 370.32 135.25 Td (potentially ) Tj ET Q q 0 0 0 rg BT 416.35 135.25 Td (registrational ) Tj ET Q q 0 0 0 rg BT 472.37 135.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 503.40 135.25 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 518.32 135.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.76 135.25 Td ( ) Tj ET Q q 0 0 0 rg BT 551.02 135.25 Td (across ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 123.25 Td (other ) Tj ET Q q 0 0 0 rg BT 154.24 123.25 Td (tumor ) Tj ET Q q 0 0 0 rg BT 181.33 123.25 Td (types ) Tj ET Q q 0 0 0 rg BT 205.63 123.25 Td (and ) Tj ET Q q 0 0 0 rg BT 223.26 123.25 Td (disease ) Tj ET Q q 0 0 0 rg BT 255.34 123.25 Td (areas, ) Tj ET Q q 0 0 0 rg BT 281.57 123.25 Td (in ) Tj ET Q q 0 0 0 rg BT 292.54 123.25 Td (monotherapy ) Tj ET Q q 0 0 0 rg BT 348.50 123.25 Td (and ) Tj ET Q q 0 0 0 rg BT 366.14 123.25 Td (in ) Tj ET Q q 0 0 0 rg BT 377.11 123.25 Td (combination ) Tj ET Q q 0 0 0 rg BT 430.30 123.25 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 451.27 123.25 Td (Y) Tj ET Q q 0 0 0 rg BT 455.92 123.25 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.12 123.25 Td ( ) Tj ET Q q 0 0 0 rg BT 481.32 123.25 Td (and ) Tj ET Q q 0 0 0 rg BT 498.95 123.25 Td (various ) Tj ET Q q 0 0 0 rg BT 531.59 123.25 Td (anti-cancer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 111.25 Td (agents.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 93.25 Td (Eliquis ) Tj ET Q q 0 0 0 rg BT 130.50 93.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 158.83 93.25 Td ( ) Tj ET Q q 0 0 0 rg BT 161.92 93.25 Td (is ) Tj ET Q q 0 0 0 rg BT 171.68 93.25 Td (an ) Tj ET Q q 0 0 0 rg BT 184.21 93.25 Td (oral ) Tj ET Q q 0 0 0 rg BT 202.84 93.25 Td (Factor ) Tj ET Q q 0 0 0 rg BT 231.47 93.25 Td (Xa ) Tj ET Q q 0 0 0 rg BT 246.22 93.25 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 283.75 93.25 Td (tar) Tj ET Q q 0 0 0 rg BT 294.12 93.25 Td (geted ) Tj ET Q q 0 0 0 rg BT 318.86 93.25 Td (at ) Tj ET Q q 0 0 0 rg BT 329.17 93.25 Td (stroke ) Tj ET Q q 0 0 0 rg BT 356.69 93.25 Td (prevention ) Tj ET Q q 0 0 0 rg BT 402.54 93.25 Td (in ) Tj ET Q q 0 0 0 rg BT 413.41 93.25 Td (atrial ) Tj ET Q q 0 0 0 rg BT 437.04 93.25 Td (fibrillation ) Tj ET Q q 0 0 0 rg BT 482.89 93.25 Td (and ) Tj ET Q q 0 0 0 rg BT 500.42 93.25 Td (the ) Tj ET Q q 0 0 0 rg BT 515.72 93.25 Td (prevention ) Tj ET Q q 0 0 0 rg BT 561.57 93.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 81.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 170.76 81.25 Td (of ) Tj ET Q q 0 0 0 rg BT 181.41 81.25 Td (VTE ) Tj ET Q q 0 0 0 rg BT 203.35 81.25 Td (disorders. ) Tj ET Q endstream endobj 9 0 obj <> endobj 10 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (4) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Or) Tj ET Q q 0 0 0 rg BT 46.74 749.10 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 68.40 749.10 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 749.10 Td (Or) Tj ET Q q 0 0 0 rg BT 141.24 749.10 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 162.90 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 167.29 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 173.62 749.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 215.50 749.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 250.44 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 259.00 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 265.33 749.10 Td (fusion ) Tj ET Q q 0 0 0 rg BT 292.23 749.10 Td (protein ) Tj ET Q q 0 0 0 rg BT 322.44 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 342.11 749.10 Td (novel ) Tj ET Q q 0 0 0 rg BT 366.22 749.10 Td (immunosuppressive ) Tj ET Q q 0 0 0 rg BT 448.11 749.10 Td (activity ) Tj ET Q q 0 0 0 rg BT 479.99 749.10 Td (tar) Tj ET Q q 0 0 0 rg BT 490.36 749.10 Td (geted ) Tj ET Q q 0 0 0 rg BT 513.91 749.10 Td (initially ) Tj ET Q q 0 0 0 rg BT 546.91 749.10 Td (at ) Tj ET Q q 0 0 0 rg BT 556.02 749.10 Td (adult ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 737.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 163.47 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 183.12 737.10 Td (moderately ) Tj ET Q q 0 0 0 rg BT 229.97 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 239.61 737.10 Td (severely ) Tj ET Q q 0 0 0 rg BT 274.79 737.10 Td (active ) Tj ET Q q 0 0 0 rg BT 300.53 737.10 Td (RA) Tj ET Q q 0 0 0 rg BT 313.87 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 315.74 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 332.05 737.10 Td (PSA) Tj ET Q q 0 0 0 rg BT 349.84 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 351.71 737.10 Td (who ) Tj ET Q q 0 0 0 rg BT 370.80 737.10 Td (have ) Tj ET Q q 0 0 0 rg BT 391.54 737.10 Td (had ) Tj ET Q q 0 0 0 rg BT 407.85 737.10 Td (an ) Tj ET Q q 0 0 0 rg BT 419.15 737.10 Td (inadequate ) Tj ET Q q 0 0 0 rg BT 464.33 737.10 Td (response ) Tj ET Q q 0 0 0 rg BT 501.19 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 510.84 737.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 539.91 737.10 Td (currently ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 725.10 Td (available ) Tj ET Q q 0 0 0 rg BT 169.50 725.10 Td (treatments. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 216.56 725.10 Td (Or) Tj ET Q q 0 0 0 rg BT 227.31 725.10 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.96 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 251.87 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 261.46 725.10 Td (also ) Tj ET Q q 0 0 0 rg BT 280.48 725.10 Td (indicated ) Tj ET Q q 0 0 0 rg BT 320.04 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 334.61 725.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 364.73 725.10 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 402.62 725.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 436.64 725.10 Td (with ) Tj ET Q q 0 0 0 rg BT 457.33 725.10 Td (moderately ) Tj ET Q q 0 0 0 rg BT 505.22 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 515.91 725.10 Td (severely ) Tj ET Q q 0 0 0 rg BT 552.14 725.10 Td (active ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 713.10 Td (polyarticular ) Tj ET Q q 0 0 0 rg BT 184.09 713.10 Td (juvenile ) Tj ET Q q 0 0 0 rg BT 218.80 713.10 Td (idiopathic ) Tj ET Q q 0 0 0 rg BT 261.29 713.10 Td (arthritis. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 695.10 Td (Sprycel ) Tj ET Q q 0 0 0 rg BT 130.50 695.10 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 160.49 695.10 Td ( ) Tj ET Q q 0 0 0 rg BT 161.98 695.10 Td (is ) Tj ET Q q 0 0 0 rg BT 170.15 695.10 Td (a ) Tj ET Q q 0 0 0 rg BT 176.09 695.10 Td (multi-tar) Tj ET Q q 0 0 0 rg BT 210.90 695.10 Td (geted ) Tj ET Q q 0 0 0 rg BT 234.05 695.10 Td (tyrosine ) Tj ET Q q 0 0 0 rg BT 267.77 695.10 Td (kinase ) Tj ET Q q 0 0 0 rg BT 294.82 695.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 330.76 695.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 369.46 695.10 Td (for ) Tj ET Q q 0 0 0 rg BT 382.62 695.10 Td (the ) Tj ET Q q 0 0 0 rg BT 396.34 695.10 Td (first-line ) Tj ET Q q 0 0 0 rg BT 432.27 695.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 471.53 695.10 Td (of ) Tj ET Q q 0 0 0 rg BT 481.36 695.10 Td (adults ) Tj ET Q q 0 0 0 rg BT 506.75 695.10 Td (with ) Tj ET Q q 0 0 0 rg BT 526.02 695.10 Td (Philadelphia ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 683.10 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 220.38 683.10 Td (CML) Tj ET Q q 0 0 0 rg BT 241.68 683.10 Td ( ) Tj ET Q q 0 0 0 rg BT 244.90 683.10 Td (in ) Tj ET Q q 0 0 0 rg BT 255.91 683.10 Td (chronic ) Tj ET Q q 0 0 0 rg BT 289.12 683.10 Td (phase, ) Tj ET Q q 0 0 0 rg BT 317.62 683.10 Td (the ) Tj ET Q q 0 0 0 rg BT 333.06 683.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 374.05 683.10 Td (of ) Tj ET Q q 0 0 0 rg BT 385.61 683.10 Td (adults ) Tj ET Q q 0 0 0 rg BT 412.72 683.10 Td (with ) Tj ET Q q 0 0 0 rg BT 433.73 683.10 Td (chronic, ) Tj ET Q q 0 0 0 rg BT 469.44 683.10 Td (accelerated, ) Tj ET Q q 0 0 0 rg BT 520.12 683.10 Td (or ) Tj ET Q q 0 0 0 rg BT 531.68 683.10 Td (myeloid ) Tj ET Q q 0 0 0 rg BT 567.68 683.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 671.10 Td (lymphoid ) Tj ET Q q 0 0 0 rg BT 170.42 671.10 Td (blast ) Tj ET Q q 0 0 0 rg BT 190.88 671.10 Td (phase ) Tj ET Q q 0 0 0 rg BT 215.23 671.10 Td (chronic ) Tj ET Q q 0 0 0 rg BT 246.80 671.10 Td (myeloid ) Tj ET Q q 0 0 0 rg BT 281.15 671.10 Td (leukemia ) Tj ET Q q 0 0 0 rg BT 319.39 671.10 Td (with ) Tj ET Q q 0 0 0 rg BT 338.75 671.10 Td (resistance ) Tj ET Q q 0 0 0 rg BT 379.75 671.10 Td (or ) Tj ET Q q 0 0 0 rg BT 389.66 671.10 Td (intolerance ) Tj ET Q q 0 0 0 rg BT 435.66 671.10 Td (to ) Tj ET Q q 0 0 0 rg BT 445.02 671.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 466.04 671.10 Td (therapy) Tj ET Q q 0 0 0 rg BT 495.38 671.10 Td (, ) Tj ET Q q 0 0 0 rg BT 499.46 671.10 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 538.81 671.10 Td (Gleevec* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 659.10 Td (\(imatinib ) Tj ET Q q 0 0 0 rg BT 169.14 659.10 Td (mesylate\) ) Tj ET Q q 0 0 0 rg BT 209.99 659.10 Td (and ) Tj ET Q q 0 0 0 rg BT 226.40 659.10 Td (the ) Tj ET Q q 0 0 0 rg BT 240.60 659.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 280.33 659.10 Td (of ) Tj ET Q q 0 0 0 rg BT 290.64 659.10 Td (children ) Tj ET Q q 0 0 0 rg BT 325.38 659.10 Td (with ) Tj ET Q q 0 0 0 rg BT 345.14 659.10 Td (Philadelphia ) Tj ET Q q 0 0 0 rg BT 397.11 659.10 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 485.73 659.10 Td (CML) Tj ET Q q 0 0 0 rg BT 507.03 659.10 Td ( ) Tj ET Q q 0 0 0 rg BT 509.01 659.10 Td (in ) Tj ET Q q 0 0 0 rg BT 518.77 659.10 Td (chronic ) Tj ET Q q 0 0 0 rg BT 550.73 659.10 Td (phase. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (Y) Tj ET Q q 0 0 0 rg BT 40.64 641.10 Td (ervoy ) Tj ET Q q 0 0 0 rg BT 130.50 641.10 Td (Y) Tj ET Q q 0 0 0 rg BT 135.14 641.10 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.35 641.10 Td (, ) Tj ET Q q 0 0 0 rg BT 163.18 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 170.94 641.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 214.25 641.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 250.63 641.10 Td (is ) Tj ET Q q 0 0 0 rg BT 260.62 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 268.39 641.10 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 318.92 641.10 Td (antibody ) Tj ET Q q 0 0 0 rg BT 357.24 641.10 Td (for ) Tj ET Q q 0 0 0 rg BT 372.23 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 387.77 641.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 428.85 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.51 641.10 Td (adults ) Tj ET Q q 0 0 0 rg BT 467.72 641.10 Td (and ) Tj ET Q q 0 0 0 rg BT 485.49 641.10 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 523.79 641.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 558.22 641.10 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 629.10 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 183.76 629.10 Td (or ) Tj ET Q q 0 0 0 rg BT 195.37 629.10 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 239.19 629.10 Td (melanoma, ) Tj ET Q q 0 0 0 rg BT 286.63 629.10 Td (as ) Tj ET Q q 0 0 0 rg BT 298.24 629.10 Td (well ) Tj ET Q q 0 0 0 rg BT 318.75 629.10 Td (as ) Tj ET Q q 0 0 0 rg BT 330.36 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 345.86 629.10 Td (adjuvant ) Tj ET Q q 0 0 0 rg BT 383.58 629.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 424.63 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 436.24 629.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 470.63 629.10 Td (with ) Tj ET Q q 0 0 0 rg BT 491.69 629.10 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 536.63 629.10 Td (who ) Tj ET Q q 0 0 0 rg BT 557.14 629.10 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 617.10 Td (under) Tj ET Q q 0 0 0 rg BT 153.09 617.10 Td (gone ) Tj ET Q q 0 0 0 rg BT 175.03 617.10 Td (complete ) Tj ET Q q 0 0 0 rg BT 214.18 617.10 Td (resection. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 599.10 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.66 599.10 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 599.10 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 167.16 599.10 Td (, ) Tj ET Q q 0 0 0 rg BT 172.16 599.10 Td (a ) Tj ET Q q 0 0 0 rg BT 179.10 599.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 221.59 599.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 257.14 599.10 Td (is ) Tj ET Q q 0 0 0 rg BT 266.31 599.10 Td (a ) Tj ET Q q 0 0 0 rg BT 273.24 599.10 Td (humanized ) Tj ET Q q 0 0 0 rg BT 319.62 599.10 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 369.33 599.10 Td (antibody ) Tj ET Q q 0 0 0 rg BT 406.82 599.10 Td (for ) Tj ET Q q 0 0 0 rg BT 420.98 599.10 Td (the ) Tj ET Q q 0 0 0 rg BT 435.70 599.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 475.96 599.10 Td (of ) Tj ET Q q 0 0 0 rg BT 486.79 599.10 Td (multiple ) Tj ET Q q 0 0 0 rg BT 522.62 599.10 Td (myeloma. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (Baraclude ) Tj ET Q q 0 0 0 rg BT 130.50 581.10 Td (Baraclude) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 172.16 581.10 Td ( ) Tj ET Q q 0 0 0 rg BT 174.66 581.10 Td (is ) Tj ET Q q 0 0 0 rg BT 183.83 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 190.76 581.10 Td (potent ) Tj ET Q q 0 0 0 rg BT 218.26 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 235.20 581.10 Td (selective ) Tj ET Q q 0 0 0 rg BT 272.68 581.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 309.62 581.10 Td (of ) Tj ET Q q 0 0 0 rg BT 320.45 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.17 581.10 Td (hepatitis ) Tj ET Q q 0 0 0 rg BT 371.55 581.10 Td (B ) Tj ET Q q 0 0 0 rg BT 380.72 581.10 Td (virus. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 563.10 Td (Sustiva ) Tj ET Q q 0 0 0 rg BT 67.39 563.10 Td (Franchise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 563.10 Td (The ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 148.01 563.10 Td (Sustiva ) Tj ET Q q 0 0 0 rg BT 178.86 563.10 Td (Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.41 563.10 Td ( ) Tj ET Q q 0 0 0 rg BT 221.37 563.10 Td (includes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 256.66 563.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 285.54 563.10 Td (, ) Tj ET Q q 0 0 0 rg BT 290.01 563.10 Td (a ) Tj ET Q q 0 0 0 rg BT 296.41 563.10 Td (non-nucleoside ) Tj ET Q q 0 0 0 rg BT 359.46 563.10 Td (reverse ) Tj ET Q q 0 0 0 rg BT 390.29 563.10 Td (transcriptase ) Tj ET Q q 0 0 0 rg BT 442.79 563.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 479.20 563.10 Td (for ) Tj ET Q q 0 0 0 rg BT 492.82 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 507.00 563.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 546.72 563.10 Td (of ) Tj ET Q q 0 0 0 rg BT 557.01 563.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 573.50 563.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 551.10 Td (as ) Tj ET Q q 0 0 0 rg BT 141.33 551.10 Td (well ) Tj ET Q q 0 0 0 rg BT 161.05 551.10 Td (as ) Tj ET Q q 0 0 0 rg BT 171.88 551.10 Td (bulk ) Tj ET Q q 0 0 0 rg BT 192.16 551.10 Td (efavirenz ) Tj ET Q q 0 0 0 rg BT 231.85 551.10 Td (which ) Tj ET Q q 0 0 0 rg BT 258.79 551.10 Td (is ) Tj ET Q q 0 0 0 rg BT 267.96 551.10 Td (included ) Tj ET Q q 0 0 0 rg BT 304.89 551.10 Td (in ) Tj ET Q q 0 0 0 rg BT 315.17 551.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.88 551.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 382.38 551.10 Td (therapy ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 414.86 551.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.20 551.10 Td (. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (Reyataz ) Tj ET Q q 0 0 0 rg BT 70.16 533.10 Td (Franchise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 533.10 Td (The ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 148.36 533.10 Td (Reyataz ) Tj ET Q q 0 0 0 rg BT 182.33 533.10 Td (Franchise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 225.19 533.10 Td (includes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 260.83 533.10 Td (Reyataz, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 297.30 533.10 Td (a ) Tj ET Q q 0 0 0 rg BT 304.05 533.10 Td (protease ) Tj ET Q q 0 0 0 rg BT 339.68 533.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 376.44 533.10 Td (for ) Tj ET Q q 0 0 0 rg BT 390.42 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 404.95 533.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 445.02 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 455.67 533.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 472.15 533.10 Td (, ) Tj ET Q q 0 0 0 rg BT 476.96 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 493.72 533.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 546.02 533.10 Td (therapy ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 521.10 Td (Evotaz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.72 521.10 Td ( ) Tj ET Q q 0 0 0 rg BT 160.22 521.10 Td (combining ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 205.49 521.10 Td (Reyataz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 237.15 521.10 Td ( ) Tj ET Q q 0 0 0 rg BT 239.65 521.10 Td (and ) Tj ET Q q 0 0 0 rg BT 256.58 521.10 Td (Gilead's ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 291.43 521.10 Td (T) Tj ET Q q 0 0 0 rg BT 296.25 521.10 Td (ybost*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.36 521.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 503.10 Td (Hepatitis ) Tj ET Q q 0 0 0 rg BT 74.60 503.10 Td (C ) Tj ET Q q 0 0 0 rg BT 83.77 503.10 Td (Franchise ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 503.10 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 166.61 503.10 Td ( ) Tj ET Q q 0 0 0 rg BT 168.98 503.10 Td (\(daclatasvir ) Tj ET Q q 0 0 0 rg BT 218.00 503.10 Td (\(DCV\)\) ) Tj ET Q q 0 0 0 rg BT 251.48 503.10 Td (is ) Tj ET Q q 0 0 0 rg BT 260.52 503.10 Td (an ) Tj ET Q q 0 0 0 rg BT 272.34 503.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 290.26 503.10 Td (small ) Tj ET Q q 0 0 0 rg BT 314.30 503.10 Td (molecule ) Tj ET Q q 0 0 0 rg BT 353.33 503.10 Td (NS5A) Tj ET Q q 0 0 0 rg BT 377.78 503.10 Td ( ) Tj ET Q q 0 0 0 rg BT 380.16 503.10 Td (replication ) Tj ET Q q 0 0 0 rg BT 425.29 503.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 462.10 503.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 498.92 503.10 Td (for ) Tj ET Q q 0 0 0 rg BT 512.95 503.10 Td (the ) Tj ET Q q 0 0 0 rg BT 527.55 503.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 567.68 503.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 491.10 Td (HCV) Tj ET Q q 0 0 0 rg BT 150.32 491.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 130.50 473.10 Td (Sunvepra ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 170.64 473.10 Td (\(asunaprevir ) Tj ET Q q 0 0 0 rg BT 222.98 473.10 Td (\(ASV\)\) ) Tj ET Q q 0 0 0 rg BT 255.34 473.10 Td (is ) Tj ET Q q 0 0 0 rg BT 264.38 473.10 Td (an ) Tj ET Q q 0 0 0 rg BT 276.18 473.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 294.10 473.10 Td (small ) Tj ET Q q 0 0 0 rg BT 318.13 473.10 Td (molecule ) Tj ET Q q 0 0 0 rg BT 357.15 473.10 Td (NS3 ) Tj ET Q q 0 0 0 rg BT 377.30 473.10 Td (protease ) Tj ET Q q 0 0 0 rg BT 412.98 473.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 449.79 473.10 Td (for ) Tj ET Q q 0 0 0 rg BT 463.82 473.10 Td (the ) Tj ET Q q 0 0 0 rg BT 478.40 473.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 518.53 473.10 Td (of ) Tj ET Q q 0 0 0 rg BT 529.23 473.10 Td (HCV) Tj ET Q q 0 0 0 rg BT 550.16 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 552.53 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 569.33 473.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.50 461.10 Td (part ) Tj ET Q q 0 0 0 rg BT 148.55 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 159.38 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 174.09 461.10 Td (dual ) Tj ET Q q 0 0 0 rg BT 193.81 461.10 Td (regimen ) Tj ET Q q 0 0 0 rg BT 229.07 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 239.90 461.10 Td (DCV+ASV) Tj ET Q q 0 0 0 rg BT 286.48 461.10 Td ( ) Tj ET Q q 0 0 0 rg BT 288.98 461.10 Td (in ) Tj ET Q q 0 0 0 rg BT 299.26 461.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 324.53 461.10 Td (and ) Tj ET Q q 0 0 0 rg BT 341.47 461.10 Td (China.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 437.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.37 437.10 Td (own ) Tj ET Q q 0 0 0 rg BT 70.89 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 81.52 437.10 Td (license ) Tj ET Q q 0 0 0 rg BT 111.58 437.10 Td (a ) Tj ET Q q 0 0 0 rg BT 118.32 437.10 Td (number ) Tj ET Q q 0 0 0 rg BT 151.16 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 161.79 437.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 192.41 437.10 Td (in ) Tj ET Q q 0 0 0 rg BT 202.49 437.10 Td (the ) Tj ET Q q 0 0 0 rg BT 217.00 437.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 237.08 437.10 Td (and ) Tj ET Q q 0 0 0 rg BT 253.82 437.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 284.99 437.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 323.94 437.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 363.45 437.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 400.74 437.10 Td (our ) Tj ET Q q 0 0 0 rg BT 416.36 437.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 455.43 437.10 Td (W) Tj ET Q q 0 0 0 rg BT 464.07 437.10 Td (e ) Tj ET Q q 0 0 0 rg BT 470.81 437.10 Td (have ) Tj ET Q q 0 0 0 rg BT 491.98 437.10 Td (also ) Tj ET Q q 0 0 0 rg BT 510.39 437.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 553.78 437.10 Td (many ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (brand ) Tj ET Q q 0 0 0 rg BT 60.51 425.10 Td (names ) Tj ET Q q 0 0 0 rg BT 87.80 425.10 Td (and ) Tj ET Q q 0 0 0 rg BT 103.98 425.10 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 150.14 425.10 Td (for ) Tj ET Q q 0 0 0 rg BT 163.54 425.10 Td (our ) Tj ET Q q 0 0 0 rg BT 178.61 425.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 217.17 425.10 Td (W) Tj ET Q q 0 0 0 rg BT 225.80 425.10 Td (e ) Tj ET Q q 0 0 0 rg BT 231.98 425.10 Td (consider ) Tj ET Q q 0 0 0 rg BT 267.60 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 281.56 425.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 311.06 425.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 353.34 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 363.42 425.10 Td (our ) Tj ET Q q 0 0 0 rg BT 378.49 425.10 Td (patents, ) Tj ET Q q 0 0 0 rg BT 411.05 425.10 Td (trademarks, ) Tj ET Q q 0 0 0 rg BT 459.72 425.10 Td (licenses ) Tj ET Q q 0 0 0 rg BT 493.11 425.10 Td (and ) Tj ET Q q 0 0 0 rg BT 509.29 425.10 Td (other ) Tj ET Q q 0 0 0 rg BT 531.58 425.10 Td (intellectual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (property ) Tj ET Q q 0 0 0 rg BT 72.38 413.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 97.66 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 107.93 413.10 Td (be ) Tj ET Q q 0 0 0 rg BT 119.87 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 130.70 413.10 Td (material ) Tj ET Q q 0 0 0 rg BT 165.96 413.10 Td (value ) Tj ET Q q 0 0 0 rg BT 190.12 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 207.05 413.10 Td (act ) Tj ET Q q 0 0 0 rg BT 221.21 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 231.49 413.10 Td (protect ) Tj ET Q q 0 0 0 rg BT 261.75 413.10 Td (these ) Tj ET Q q 0 0 0 rg BT 284.80 413.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 310.08 413.10 Td (from ) Tj ET Q q 0 0 0 rg BT 332.02 413.10 Td (infringement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 390.30 Td (In ) Tj ET Q q 0 0 0 rg BT 46.87 390.30 Td (the ) Tj ET Q q 0 0 0 rg BT 61.63 390.30 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 125.25 390.30 Td (industry) Tj ET Q q 0 0 0 rg BT 157.38 390.30 Td (, ) Tj ET Q q 0 0 0 rg BT 162.42 390.30 Td (the ) Tj ET Q q 0 0 0 rg BT 177.18 390.30 Td (majority ) Tj ET Q q 0 0 0 rg BT 213.61 390.30 Td (of ) Tj ET Q q 0 0 0 rg BT 224.48 390.30 Td (an ) Tj ET Q q 0 0 0 rg BT 236.46 390.30 Td (innovative ) Tj ET Q q 0 0 0 rg BT 281.22 390.30 Td (product’) Tj ET Q q 0 0 0 rg BT 314.54 390.30 Td (s ) Tj ET Q q 0 0 0 rg BT 320.98 390.30 Td (commercial ) Tj ET Q q 0 0 0 rg BT 370.72 390.30 Td (value ) Tj ET Q q 0 0 0 rg BT 394.91 390.30 Td (is ) Tj ET Q q 0 0 0 rg BT 404.13 390.30 Td (usually ) Tj ET Q q 0 0 0 rg BT 435.56 390.30 Td (realized ) Tj ET Q q 0 0 0 rg BT 469.74 390.30 Td (during ) Tj ET Q q 0 0 0 rg BT 498.39 390.30 Td (the ) Tj ET Q q 0 0 0 rg BT 513.15 390.30 Td (period ) Tj ET Q q 0 0 0 rg BT 541.24 390.30 Td (in ) Tj ET Q q 0 0 0 rg BT 551.56 390.30 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 378.30 Td (the ) Tj ET Q q 0 0 0 rg BT 50.68 378.30 Td (product ) Tj ET Q q 0 0 0 rg BT 83.70 378.30 Td (has ) Tj ET Q q 0 0 0 rg BT 99.50 378.30 Td (market ) Tj ET Q q 0 0 0 rg BT 129.73 378.30 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 172.96 378.30 Td (. ) Tj ET Q q 0 0 0 rg BT 177.38 378.30 Td (A) Tj ET Q q 0 0 0 rg BT 184.05 378.30 Td ( ) Tj ET Q q 0 0 0 rg BT 186.52 378.30 Td (product’) Tj ET Q q 0 0 0 rg BT 219.84 378.30 Td (s ) Tj ET Q q 0 0 0 rg BT 226.20 378.30 Td (market ) Tj ET Q q 0 0 0 rg BT 256.43 378.30 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 302.78 378.30 Td (is ) Tj ET Q q 0 0 0 rg BT 311.92 378.30 Td (generally ) Tj ET Q q 0 0 0 rg BT 351.59 378.30 Td (determined ) Tj ET Q q 0 0 0 rg BT 399.04 378.30 Td (by ) Tj ET Q q 0 0 0 rg BT 411.50 378.30 Td (two ) Tj ET Q q 0 0 0 rg BT 428.97 378.30 Td (forms ) Tj ET Q q 0 0 0 rg BT 454.77 378.30 Td (of ) Tj ET Q q 0 0 0 rg BT 465.57 378.30 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 512.46 378.30 Td (property: ) Tj ET Q q 0 0 0 rg BT 551.58 378.30 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 366.30 Td (rights ) Tj ET Q q 0 0 0 rg BT 61.28 366.30 Td (held ) Tj ET Q q 0 0 0 rg BT 81.00 366.30 Td (by ) Tj ET Q q 0 0 0 rg BT 93.50 366.30 Td (the ) Tj ET Q q 0 0 0 rg BT 108.21 366.30 Td (innovator ) Tj ET Q q 0 0 0 rg BT 149.04 366.30 Td (company ) Tj ET Q q 0 0 0 rg BT 188.19 366.30 Td (and ) Tj ET Q q 0 0 0 rg BT 205.13 366.30 Td (any ) Tj ET Q q 0 0 0 rg BT 222.07 366.30 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 265.66 366.30 Td (forms ) Tj ET Q q 0 0 0 rg BT 291.49 366.30 Td (of ) Tj ET Q q 0 0 0 rg BT 302.32 366.30 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 348.71 366.30 Td (to ) Tj ET Q q 0 0 0 rg BT 358.98 366.30 Td (which ) Tj ET Q q 0 0 0 rg BT 385.92 366.30 Td (the ) Tj ET Q q 0 0 0 rg BT 400.64 366.30 Td (innovative ) Tj ET Q q 0 0 0 rg BT 445.35 366.30 Td (drug ) Tj ET Q q 0 0 0 rg BT 466.18 366.30 Td (is ) Tj ET Q q 0 0 0 rg BT 475.35 366.30 Td (entitled.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 343.50 Td (Patents ) Tj ET Q q 0 0 0 rg BT 67.77 343.50 Td (are ) Tj ET Q q 0 0 0 rg BT 82.87 343.50 Td (a ) Tj ET Q q 0 0 0 rg BT 90.20 343.50 Td (key ) Tj ET Q q 0 0 0 rg BT 107.52 343.50 Td (determinant ) Tj ET Q q 0 0 0 rg BT 158.17 343.50 Td (of ) Tj ET Q q 0 0 0 rg BT 169.39 343.50 Td (market ) Tj ET Q q 0 0 0 rg BT 200.04 343.50 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 246.81 343.50 Td (for ) Tj ET Q q 0 0 0 rg BT 261.36 343.50 Td (most ) Tj ET Q q 0 0 0 rg BT 283.70 343.50 Td (branded ) Tj ET Q q 0 0 0 rg BT 318.79 343.50 Td (pharmaceuticals. ) Tj ET Q q 0 0 0 rg BT 389.14 343.50 Td (Patents ) Tj ET Q q 0 0 0 rg BT 420.92 343.50 Td (provide ) Tj ET Q q 0 0 0 rg BT 454.35 343.50 Td (the ) Tj ET Q q 0 0 0 rg BT 469.46 343.50 Td (innovator ) Tj ET Q q 0 0 0 rg BT 510.67 343.50 Td (with ) Tj ET Q q 0 0 0 rg BT 531.34 343.50 Td (the ) Tj ET Q q 0 0 0 rg BT 546.44 343.50 Td (right ) Tj ET Q q 0 0 0 rg BT 568.22 343.50 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 331.50 Td (exclude ) Tj ET Q q 0 0 0 rg BT 70.24 331.50 Td (others ) Tj ET Q q 0 0 0 rg BT 97.83 331.50 Td (from ) Tj ET Q q 0 0 0 rg BT 120.42 331.50 Td (practicing ) Tj ET Q q 0 0 0 rg BT 163.55 331.50 Td (an ) Tj ET Q q 0 0 0 rg BT 176.14 331.50 Td (invention ) Tj ET Q q 0 0 0 rg BT 217.06 331.50 Td (related ) Tj ET Q q 0 0 0 rg BT 247.41 331.50 Td (to ) Tj ET Q q 0 0 0 rg BT 258.34 331.50 Td (the ) Tj ET Q q 0 0 0 rg BT 273.71 331.50 Td (medicine. ) Tj ET Q q 0 0 0 rg BT 316.00 331.50 Td (Patents ) Tj ET Q q 0 0 0 rg BT 348.04 331.50 Td (may ) Tj ET Q q 0 0 0 rg BT 368.41 331.50 Td (cover) Tj ET Q q 0 0 0 rg BT 390.21 331.50 Td (, ) Tj ET Q q 0 0 0 rg BT 395.86 331.50 Td (among ) Tj ET Q q 0 0 0 rg BT 426.23 331.50 Td (other ) Tj ET Q q 0 0 0 rg BT 449.93 331.50 Td (things, ) Tj ET Q q 0 0 0 rg BT 480.02 331.50 Td (the ) Tj ET Q q 0 0 0 rg BT 495.39 331.50 Td (active ) Tj ET Q q 0 0 0 rg BT 522.41 331.50 Td (ingredient\(s\), ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 319.50 Td (various ) Tj ET Q q 0 0 0 rg BT 68.29 319.50 Td (uses ) Tj ET Q q 0 0 0 rg BT 88.37 319.50 Td (of ) Tj ET Q q 0 0 0 rg BT 99.55 319.50 Td (a ) Tj ET Q q 0 0 0 rg BT 106.84 319.50 Td (drug ) Tj ET Q q 0 0 0 rg BT 128.02 319.50 Td (product, ) Tj ET Q q 0 0 0 rg BT 163.92 319.50 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 227.85 319.50 Td (formulations, ) Tj ET Q q 0 0 0 rg BT 284.31 319.50 Td (drug ) Tj ET Q q 0 0 0 rg BT 305.49 319.50 Td (delivery ) Tj ET Q q 0 0 0 rg BT 341.11 319.50 Td (mechanisms ) Tj ET Q q 0 0 0 rg BT 393.39 319.50 Td (and ) Tj ET Q q 0 0 0 rg BT 410.69 319.50 Td (processes ) Tj ET Q q 0 0 0 rg BT 451.86 319.50 Td (for ) Tj ET Q q 0 0 0 rg BT 466.37 319.50 Td (\(or ) Tj ET Q q 0 0 0 rg BT 480.89 319.50 Td (intermediates ) Tj ET Q q 0 0 0 rg BT 537.61 319.50 Td (useful ) Tj ET Q q 0 0 0 rg BT 564.90 319.50 Td (in\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 307.50 Td (the ) Tj ET Q q 0 0 0 rg BT 51.02 307.50 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 103.79 307.50 Td (of ) Tj ET Q q 0 0 0 rg BT 114.93 307.50 Td (products. ) Tj ET Q q 0 0 0 rg BT 154.67 307.50 Td (Protection ) Tj ET Q q 0 0 0 rg BT 198.57 307.50 Td (for ) Tj ET Q q 0 0 0 rg BT 213.04 307.50 Td (individual ) Tj ET Q q 0 0 0 rg BT 256.39 307.50 Td (products ) Tj ET Q q 0 0 0 rg BT 293.63 307.50 Td (extends ) Tj ET Q q 0 0 0 rg BT 326.98 307.50 Td (for ) Tj ET Q q 0 0 0 rg BT 341.44 307.50 Td (varying ) Tj ET Q q 0 0 0 rg BT 374.79 307.50 Td (periods ) Tj ET Q q 0 0 0 rg BT 407.04 307.50 Td (in ) Tj ET Q q 0 0 0 rg BT 417.62 307.50 Td (accordance ) Tj ET Q q 0 0 0 rg BT 465.38 307.50 Td (with ) Tj ET Q q 0 0 0 rg BT 485.96 307.50 Td (the ) Tj ET Q q 0 0 0 rg BT 500.98 307.50 Td (expiration ) Tj ET Q q 0 0 0 rg BT 544.33 307.50 Td (dates ) Tj ET Q q 0 0 0 rg BT 567.67 307.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 295.50 Td (patents ) Tj ET Q q 0 0 0 rg BT 66.60 295.50 Td (in ) Tj ET Q q 0 0 0 rg BT 76.66 295.50 Td (the ) Tj ET Q q 0 0 0 rg BT 91.15 295.50 Td (various ) Tj ET Q q 0 0 0 rg BT 122.87 295.50 Td (countries. ) Tj ET Q q 0 0 0 rg BT 164.14 295.50 Td (The ) Tj ET Q q 0 0 0 rg BT 181.96 295.50 Td (protection ) Tj ET Q q 0 0 0 rg BT 224.78 295.50 Td (af) Tj ET Q q 0 0 0 rg BT 232.37 295.50 Td (forded, ) Tj ET Q q 0 0 0 rg BT 263.25 295.50 Td (which ) Tj ET Q q 0 0 0 rg BT 289.96 295.50 Td (may ) Tj ET Q q 0 0 0 rg BT 309.46 295.50 Td (also ) Tj ET Q q 0 0 0 rg BT 327.84 295.50 Td (vary ) Tj ET Q q 0 0 0 rg BT 347.89 295.50 Td (from ) Tj ET Q q 0 0 0 rg BT 369.61 295.50 Td (country ) Tj ET Q q 0 0 0 rg BT 402.43 295.50 Td (to ) Tj ET Q q 0 0 0 rg BT 412.49 295.50 Td (country) Tj ET Q q 0 0 0 rg BT 442.39 295.50 Td (, ) Tj ET Q q 0 0 0 rg BT 447.16 295.50 Td (depends ) Tj ET Q q 0 0 0 rg BT 482.21 295.50 Td (upon ) Tj ET Q q 0 0 0 rg BT 504.49 295.50 Td (the ) Tj ET Q q 0 0 0 rg BT 518.98 295.50 Td (type ) Tj ET Q q 0 0 0 rg BT 538.48 295.50 Td (of ) Tj ET Q q 0 0 0 rg BT 549.08 295.50 Td (patent, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 283.50 Td (its ) Tj ET Q q 0 0 0 rg BT 47.95 283.50 Td (scope ) Tj ET Q q 0 0 0 rg BT 73.22 283.50 Td (of ) Tj ET Q q 0 0 0 rg BT 84.05 283.50 Td (coverage ) Tj ET Q q 0 0 0 rg BT 122.63 283.50 Td (and ) Tj ET Q q 0 0 0 rg BT 139.57 283.50 Td (the ) Tj ET Q q 0 0 0 rg BT 154.29 283.50 Td (availability ) Tj ET Q q 0 0 0 rg BT 201.77 283.50 Td (of ) Tj ET Q q 0 0 0 rg BT 212.60 283.50 Td (meaningful ) Tj ET Q q 0 0 0 rg BT 260.64 283.50 Td (legal ) Tj ET Q q 0 0 0 rg BT 282.58 283.50 Td (remedies ) Tj ET Q q 0 0 0 rg BT 321.17 283.50 Td (in ) Tj ET Q q 0 0 0 rg BT 331.45 283.50 Td (the ) Tj ET Q q 0 0 0 rg BT 346.17 283.50 Td (country) Tj ET Q q 0 0 0 rg BT 376.06 283.50 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 260.70 Td (Market ) Tj ET Q q 0 0 0 rg BT 68.24 260.70 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 115.48 260.70 Td (is ) Tj ET Q q 0 0 0 rg BT 125.51 260.70 Td (also ) Tj ET Q q 0 0 0 rg BT 144.98 260.70 Td (sometimes ) Tj ET Q q 0 0 0 rg BT 191.11 260.70 Td (influenced ) Tj ET Q q 0 0 0 rg BT 236.68 260.70 Td (by ) Tj ET Q q 0 0 0 rg BT 250.04 260.70 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 294.49 260.70 Td (data ) Tj ET Q q 0 0 0 rg BT 314.51 260.70 Td (protection ) Tj ET Q q 0 0 0 rg BT 358.41 260.70 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 405.65 260.70 Td (rights. ) Tj ET Q q 0 0 0 rg BT 434.29 260.70 Td (Many ) Tj ET Q q 0 0 0 rg BT 460.98 260.70 Td (developed ) Tj ET Q q 0 0 0 rg BT 505.44 260.70 Td (countries ) Tj ET Q q 0 0 0 rg BT 545.46 260.70 Td (provide ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 248.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.22 248.70 Td (non-patent ) Tj ET Q q 0 0 0 rg BT 112.01 248.70 Td (incentives ) Tj ET Q q 0 0 0 rg BT 155.57 248.70 Td (for ) Tj ET Q q 0 0 0 rg BT 170.25 248.70 Td (the ) Tj ET Q q 0 0 0 rg BT 185.49 248.70 Td (development ) Tj ET Q q 0 0 0 rg BT 240.16 248.70 Td (of ) Tj ET Q q 0 0 0 rg BT 251.52 248.70 Td (medicines. ) Tj ET Q q 0 0 0 rg BT 297.58 248.70 Td (For ) Tj ET Q q 0 0 0 rg BT 314.49 248.70 Td (example, ) Tj ET Q q 0 0 0 rg BT 353.89 248.70 Td (in ) Tj ET Q q 0 0 0 rg BT 364.69 248.70 Td (the ) Tj ET Q q 0 0 0 rg BT 379.92 248.70 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 403.23 248.70 Td (the ) Tj ET Q q 0 0 0 rg BT 418.47 248.70 Td (EU, ) Tj ET Q q 0 0 0 rg BT 437.32 248.70 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 465.61 248.70 Td (and ) Tj ET Q q 0 0 0 rg BT 483.07 248.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 513.29 248.70 Td (other ) Tj ET Q q 0 0 0 rg BT 536.86 248.70 Td (countries, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 236.70 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.83 236.70 Td (data ) Tj ET Q q 0 0 0 rg BT 99.23 236.70 Td (protection ) Tj ET Q q 0 0 0 rg BT 142.51 236.70 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 189.13 236.70 Td (rights ) Tj ET Q q 0 0 0 rg BT 214.65 236.70 Td (are ) Tj ET Q q 0 0 0 rg BT 229.59 236.70 Td (of) Tj ET Q q 0 0 0 rg BT 237.74 236.70 Td (fered ) Tj ET Q q 0 0 0 rg BT 261.02 236.70 Td (as ) Tj ET Q q 0 0 0 rg BT 272.09 236.70 Td (incentives ) Tj ET Q q 0 0 0 rg BT 315.37 236.70 Td (for ) Tj ET Q q 0 0 0 rg BT 329.77 236.70 Td (research ) Tj ET Q q 0 0 0 rg BT 365.81 236.70 Td (on ) Tj ET Q q 0 0 0 rg BT 378.55 236.70 Td (medicines ) Tj ET Q q 0 0 0 rg BT 421.83 236.70 Td (for ) Tj ET Q q 0 0 0 rg BT 436.23 236.70 Td (rare ) Tj ET Q q 0 0 0 rg BT 454.51 236.70 Td (diseases, ) Tj ET Q q 0 0 0 rg BT 492.52 236.70 Td (or ) Tj ET Q q 0 0 0 rg BT 503.59 236.70 Td (orphan ) Tj ET Q q 0 0 0 rg BT 534.10 236.70 Td (drugs, ) Tj ET Q q 0 0 0 rg BT 561.56 236.70 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 224.70 Td (on ) Tj ET Q q 0 0 0 rg BT 49.11 224.70 Td (medicines ) Tj ET Q q 0 0 0 rg BT 92.75 224.70 Td (useful ) Tj ET Q q 0 0 0 rg BT 120.30 224.70 Td (in ) Tj ET Q q 0 0 0 rg BT 131.18 224.70 Td (treating ) Tj ET Q q 0 0 0 rg BT 164.83 224.70 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 202.91 224.70 Td (patients. ) Tj ET Q q 0 0 0 rg BT 239.40 224.70 Td (These ) Tj ET Q q 0 0 0 rg BT 266.38 224.70 Td (incentives ) Tj ET Q q 0 0 0 rg BT 310.03 224.70 Td (can ) Tj ET Q q 0 0 0 rg BT 327.01 224.70 Td (provide ) Tj ET Q q 0 0 0 rg BT 360.66 224.70 Td (a ) Tj ET Q q 0 0 0 rg BT 368.21 224.70 Td (market ) Tj ET Q q 0 0 0 rg BT 399.08 224.70 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 446.06 224.70 Td (period ) Tj ET Q q 0 0 0 rg BT 474.72 224.70 Td (on ) Tj ET Q q 0 0 0 rg BT 487.82 224.70 Td (a ) Tj ET Q q 0 0 0 rg BT 495.37 224.70 Td (product ) Tj ET Q q 0 0 0 rg BT 529.02 224.70 Td (that ) Tj ET Q q 0 0 0 rg BT 547.12 224.70 Td (expires ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 212.70 Td (beyond ) Tj ET Q q 0 0 0 rg BT 67.94 212.70 Td (the ) Tj ET Q q 0 0 0 rg BT 82.66 212.70 Td (patent ) Tj ET Q q 0 0 0 rg BT 109.59 212.70 Td (term.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.90 Td (The ) Tj ET Q q 0 0 0 rg BT 54.67 189.90 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 78.08 189.90 Td (EU ) Tj ET Q q 0 0 0 rg BT 94.53 189.90 Td (and ) Tj ET Q q 0 0 0 rg BT 112.09 189.90 Td (Japan ) Tj ET Q q 0 0 0 rg BT 137.99 189.90 Td (each ) Tj ET Q q 0 0 0 rg BT 159.43 189.90 Td (provide ) Tj ET Q q 0 0 0 rg BT 193.10 189.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 237.32 189.90 Td (data ) Tj ET Q q 0 0 0 rg BT 257.09 189.90 Td (protection, ) Tj ET Q q 0 0 0 rg BT 303.26 189.90 Td (a ) Tj ET Q q 0 0 0 rg BT 310.82 189.90 Td (period ) Tj ET Q q 0 0 0 rg BT 339.49 189.90 Td (of ) Tj ET Q q 0 0 0 rg BT 350.95 189.90 Td (time ) Tj ET Q q 0 0 0 rg BT 371.85 189.90 Td (after ) Tj ET Q q 0 0 0 rg BT 393.29 189.90 Td (the ) Tj ET Q q 0 0 0 rg BT 408.63 189.90 Td (approval ) Tj ET Q q 0 0 0 rg BT 446.74 189.90 Td (of ) Tj ET Q q 0 0 0 rg BT 458.19 189.90 Td (a ) Tj ET Q q 0 0 0 rg BT 465.75 189.90 Td (new ) Tj ET Q q 0 0 0 rg BT 485.54 189.90 Td (drug ) Tj ET Q q 0 0 0 rg BT 506.99 189.90 Td (during ) Tj ET Q q 0 0 0 rg BT 536.22 189.90 Td (which ) Tj ET Q q 0 0 0 rg BT 563.79 189.90 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 177.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 78.53 177.90 Td (agency ) Tj ET Q q 0 0 0 rg BT 108.28 177.90 Td (may ) Tj ET Q q 0 0 0 rg BT 126.94 177.90 Td (not ) Tj ET Q q 0 0 0 rg BT 141.15 177.90 Td (rely ) Tj ET Q q 0 0 0 rg BT 158.14 177.90 Td (upon ) Tj ET Q q 0 0 0 rg BT 179.57 177.90 Td (the ) Tj ET Q q 0 0 0 rg BT 193.23 177.90 Td (innovator) Tj ET Q q 0 0 0 rg BT 231.92 177.90 Td (’) Tj ET Q q 0 0 0 rg BT 234.70 177.90 Td (s ) Tj ET Q q 0 0 0 rg BT 240.03 177.90 Td (data ) Tj ET Q q 0 0 0 rg BT 258.12 177.90 Td (to ) Tj ET Q q 0 0 0 rg BT 267.34 177.90 Td (approve ) Tj ET Q q 0 0 0 rg BT 300.98 177.90 Td (a ) Tj ET Q q 0 0 0 rg BT 306.86 177.90 Td (competitor) Tj ET Q q 0 0 0 rg BT 350.55 177.90 Td (’) Tj ET Q q 0 0 0 rg BT 353.33 177.90 Td (s ) Tj ET Q q 0 0 0 rg BT 358.66 177.90 Td (generic ) Tj ET Q q 0 0 0 rg BT 389.52 177.90 Td (copy) Tj ET Q q 0 0 0 rg BT 408.31 177.90 Td (. ) Tj ET Q q 0 0 0 rg BT 412.24 177.90 Td (In ) Tj ET Q q 0 0 0 rg BT 422.01 177.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 450.65 177.90 Td (markets ) Tj ET Q q 0 0 0 rg BT 483.74 177.90 Td (where ) Tj ET Q q 0 0 0 rg BT 509.61 177.90 Td (patent ) Tj ET Q q 0 0 0 rg BT 535.48 177.90 Td (protection ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 165.90 Td (and ) Tj ET Q q 0 0 0 rg BT 53.73 165.90 Td (other ) Tj ET Q q 0 0 0 rg BT 77.57 165.90 Td (forms ) Tj ET Q q 0 0 0 rg BT 104.19 165.90 Td (of ) Tj ET Q q 0 0 0 rg BT 115.81 165.90 Td (market ) Tj ET Q q 0 0 0 rg BT 146.86 165.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 194.03 165.90 Td (may ) Tj ET Q q 0 0 0 rg BT 214.54 165.90 Td (have ) Tj ET Q q 0 0 0 rg BT 236.71 165.90 Td (expired, ) Tj ET Q q 0 0 0 rg BT 272.48 165.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 316.86 165.90 Td (data ) Tj ET Q q 0 0 0 rg BT 336.81 165.90 Td (protection ) Tj ET Q q 0 0 0 rg BT 380.64 165.90 Td (can ) Tj ET Q q 0 0 0 rg BT 397.81 165.90 Td (be ) Tj ET Q q 0 0 0 rg BT 410.54 165.90 Td (of ) Tj ET Q q 0 0 0 rg BT 422.16 165.90 Td (particular ) Tj ET Q q 0 0 0 rg BT 463.76 165.90 Td (importance. ) Tj ET Q q 0 0 0 rg BT 514.53 165.90 Td (However) Tj ET Q q 0 0 0 rg BT 550.78 165.90 Td (, ) Tj ET Q q 0 0 0 rg BT 556.57 165.90 Td (most ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 153.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.79 153.90 Td (forms ) Tj ET Q q 0 0 0 rg BT 105.82 153.90 Td (of ) Tj ET Q q 0 0 0 rg BT 116.85 153.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 163.43 153.90 Td (do ) Tj ET Q q 0 0 0 rg BT 176.13 153.90 Td (not ) Tj ET Q q 0 0 0 rg BT 191.61 153.90 Td (prevent ) Tj ET Q q 0 0 0 rg BT 224.29 153.90 Td (a ) Tj ET Q q 0 0 0 rg BT 231.43 153.90 Td (competitor ) Tj ET Q q 0 0 0 rg BT 277.45 153.90 Td (from ) Tj ET Q q 0 0 0 rg BT 299.59 153.90 Td (gaining ) Tj ET Q q 0 0 0 rg BT 332.28 153.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 376.08 153.90 Td (approval ) Tj ET Q q 0 0 0 rg BT 413.76 153.90 Td (prior ) Tj ET Q q 0 0 0 rg BT 435.90 153.90 Td (to ) Tj ET Q q 0 0 0 rg BT 446.38 153.90 Td (the ) Tj ET Q q 0 0 0 rg BT 461.29 153.90 Td (expiration ) Tj ET Q q 0 0 0 rg BT 504.53 153.90 Td (of ) Tj ET Q q 0 0 0 rg BT 515.56 153.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 559.36 153.90 Td (data ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 141.90 Td (protection ) Tj ET Q q 0 0 0 rg BT 79.16 141.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 125.66 141.90 Td (on ) Tj ET Q q 0 0 0 rg BT 138.28 141.90 Td (the ) Tj ET Q q 0 0 0 rg BT 153.12 141.90 Td (basis ) Tj ET Q q 0 0 0 rg BT 175.74 141.90 Td (of ) Tj ET Q q 0 0 0 rg BT 186.69 141.90 Td (the ) Tj ET Q q 0 0 0 rg BT 201.52 141.90 Td (competitor) Tj ET Q q 0 0 0 rg BT 245.22 141.90 Td (’) Tj ET Q q 0 0 0 rg BT 247.99 141.90 Td (s ) Tj ET Q q 0 0 0 rg BT 254.51 141.90 Td (own ) Tj ET Q q 0 0 0 rg BT 274.35 141.90 Td (safety ) Tj ET Q q 0 0 0 rg BT 300.84 141.90 Td (and ) Tj ET Q q 0 0 0 rg BT 317.90 141.90 Td (ef) Tj ET Q q 0 0 0 rg BT 325.49 141.90 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 352.53 141.90 Td (data ) Tj ET Q q 0 0 0 rg BT 371.81 141.90 Td (on ) Tj ET Q q 0 0 0 rg BT 384.43 141.90 Td (its ) Tj ET Q q 0 0 0 rg BT 396.50 141.90 Td (drug, ) Tj ET Q q 0 0 0 rg BT 419.95 141.90 Td (even ) Tj ET Q q 0 0 0 rg BT 441.44 141.90 Td (when ) Tj ET Q q 0 0 0 rg BT 465.72 141.90 Td (that ) Tj ET Q q 0 0 0 rg BT 483.34 141.90 Td (drug ) Tj ET Q q 0 0 0 rg BT 504.29 141.90 Td (is ) Tj ET Q q 0 0 0 rg BT 513.58 141.90 Td (identical ) Tj ET Q q 0 0 0 rg BT 550.62 141.90 Td (to ) Tj ET Q q 0 0 0 rg BT 561.02 141.90 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 129.90 Td (marketed ) Tj ET Q q 0 0 0 rg BT 74.98 129.90 Td (by ) Tj ET Q q 0 0 0 rg BT 86.75 129.90 Td (the ) Tj ET Q q 0 0 0 rg BT 100.74 129.90 Td (innovator) Tj ET Q q 0 0 0 rg BT 138.52 129.90 Td (. ) Tj ET Q q 0 0 0 rg BT 142.66 129.90 Td (When ) Tj ET Q q 0 0 0 rg BT 168.32 129.90 Td (these ) Tj ET Q q 0 0 0 rg BT 190.64 129.90 Td (patent ) Tj ET Q q 0 0 0 rg BT 216.85 129.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 241.40 129.90 Td (and ) Tj ET Q q 0 0 0 rg BT 257.61 129.90 Td (other ) Tj ET Q q 0 0 0 rg BT 279.93 129.90 Td (forms ) Tj ET Q q 0 0 0 rg BT 305.04 129.90 Td (of ) Tj ET Q q 0 0 0 rg BT 315.14 129.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 360.80 129.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 387.56 129.90 Td (and ) Tj ET Q q 0 0 0 rg BT 403.77 129.90 Td (generic ) Tj ET Q q 0 0 0 rg BT 434.97 129.90 Td (versions ) Tj ET Q q 0 0 0 rg BT 470.08 129.90 Td (of ) Tj ET Q q 0 0 0 rg BT 480.18 129.90 Td (a ) Tj ET Q q 0 0 0 rg BT 486.40 129.90 Td (medicine ) Tj ET Q q 0 0 0 rg BT 524.82 129.90 Td (are ) Tj ET Q q 0 0 0 rg BT 538.80 129.90 Td (approved ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 117.90 Td (and ) Tj ET Q q 0 0 0 rg BT 52.96 117.90 Td (marketed, ) Tj ET Q q 0 0 0 rg BT 95.18 117.90 Td (there ) Tj ET Q q 0 0 0 rg BT 117.69 117.90 Td (are ) Tj ET Q q 0 0 0 rg BT 132.42 117.90 Td (often ) Tj ET Q q 0 0 0 rg BT 155.48 117.90 Td (substantial ) Tj ET Q q 0 0 0 rg BT 200.78 117.90 Td (and ) Tj ET Q q 0 0 0 rg BT 217.74 117.90 Td (rapid ) Tj ET Q q 0 0 0 rg BT 240.81 117.90 Td (declines ) Tj ET Q q 0 0 0 rg BT 276.09 117.90 Td (in ) Tj ET Q q 0 0 0 rg BT 286.39 117.90 Td (the ) Tj ET Q q 0 0 0 rg BT 301.13 117.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 323.09 117.90 Td (of ) Tj ET Q q 0 0 0 rg BT 333.94 117.90 Td (the ) Tj ET Q q 0 0 0 rg BT 348.68 117.90 Td (original ) Tj ET Q q 0 0 0 rg BT 382.30 117.90 Td (innovative ) Tj ET Q q 0 0 0 rg BT 427.03 117.90 Td (product. ) Tj ET Q q 0 0 0 rg BT 462.60 117.90 Td (For ) Tj ET Q q 0 0 0 rg BT 479.01 117.90 Td (further ) Tj ET Q q 0 0 0 rg BT 508.74 117.90 Td (discussion ) Tj ET Q q 0 0 0 rg BT 552.93 117.90 Td (of ) Tj ET Q q 0 0 0 rg BT 563.78 117.90 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 105.90 Td (impact ) Tj ET Q q 0 0 0 rg BT 65.71 105.90 Td (of ) Tj ET Q q 0 0 0 rg BT 76.54 105.90 Td (generic ) Tj ET Q q 0 0 0 rg BT 108.47 105.90 Td (competition ) Tj ET Q q 0 0 0 rg BT 158.73 105.90 Td (on ) Tj ET Q q 0 0 0 rg BT 171.23 105.90 Td (our ) Tj ET Q q 0 0 0 rg BT 187.06 105.90 Td (business, ) Tj ET Q q 0 0 0 rg BT 225.96 105.90 Td (refer ) Tj ET Q q 0 0 0 rg BT 247.32 105.90 Td (to ) Tj ET Q q 0 0 0 rg BT 257.60 105.90 Td (“—Generic ) Tj ET Q q 0 0 0 rg BT 306.19 105.90 Td (Competition”.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 83.10 Td (Specific ) Tj ET Q q 0 0 0 rg BT 70.65 83.10 Td (aspects ) Tj ET Q q 0 0 0 rg BT 101.41 83.10 Td (of ) Tj ET Q q 0 0 0 rg BT 111.62 83.10 Td (the ) Tj ET Q q 0 0 0 rg BT 125.72 83.10 Td (law ) Tj ET Q q 0 0 0 rg BT 142.04 83.10 Td (governing ) Tj ET Q q 0 0 0 rg BT 184.48 83.10 Td (market ) Tj ET Q q 0 0 0 rg BT 214.12 83.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 259.89 83.10 Td (and ) Tj ET Q q 0 0 0 rg BT 276.21 83.10 Td (data ) Tj ET Q q 0 0 0 rg BT 294.75 83.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 337.73 83.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 380.15 83.10 Td (for ) Tj ET Q q 0 0 0 rg BT 393.70 83.10 Td (pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 460.55 83.10 Td (vary ) Tj ET Q q 0 0 0 rg BT 480.20 83.10 Td (from ) Tj ET Q q 0 0 0 rg BT 501.52 83.10 Td (country ) Tj ET Q q 0 0 0 rg BT 533.95 83.10 Td (to ) Tj ET Q q 0 0 0 rg BT 543.61 83.10 Td (country) Tj ET Q q 0 0 0 rg BT 573.51 83.10 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 71.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 71.10 Td (following ) Tj ET Q q 0 0 0 rg BT 95.43 71.10 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 145.70 71.10 Td (key ) Tj ET Q q 0 0 0 rg BT 162.64 71.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 209.02 71.10 Td (rules ) Tj ET Q q 0 0 0 rg BT 230.96 71.10 Td (in ) Tj ET Q q 0 0 0 rg BT 241.23 71.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 275.39 71.10 Td (representing ) Tj ET Q q 0 0 0 rg BT 327.31 71.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 372.03 71.10 Td (sales:) Tj ET Q endstream endobj 11 0 obj <> endobj 12 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (5) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (United States) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 731.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.87 731.10 Td (the ) Tj ET Q q 0 0 0 rg BT 61.63 731.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 84.45 731.10 Td (most ) Tj ET Q q 0 0 0 rg BT 106.43 731.10 Td (of ) Tj ET Q q 0 0 0 rg BT 117.30 731.10 Td (our ) Tj ET Q q 0 0 0 rg BT 133.17 731.10 Td (key ) Tj ET Q q 0 0 0 rg BT 150.15 731.10 Td (products ) Tj ET Q q 0 0 0 rg BT 187.13 731.10 Td (are ) Tj ET Q q 0 0 0 rg BT 201.87 731.10 Td (protected ) Tj ET Q q 0 0 0 rg BT 241.62 731.10 Td (by ) Tj ET Q q 0 0 0 rg BT 254.15 731.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 285.02 731.10 Td (with ) Tj ET Q q 0 0 0 rg BT 305.34 731.10 Td (varying ) Tj ET Q q 0 0 0 rg BT 338.42 731.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 363.18 731.10 Td (depending ) Tj ET Q q 0 0 0 rg BT 407.37 731.10 Td (on ) Tj ET Q q 0 0 0 rg BT 419.91 731.10 Td (the ) Tj ET Q q 0 0 0 rg BT 434.67 731.10 Td (type ) Tj ET Q q 0 0 0 rg BT 454.42 731.10 Td (of ) Tj ET Q q 0 0 0 rg BT 465.29 731.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 492.26 731.10 Td (and ) Tj ET Q q 0 0 0 rg BT 509.24 731.10 Td (the ) Tj ET Q q 0 0 0 rg BT 524.00 731.10 Td (filing ) Tj ET Q q 0 0 0 rg BT 548.20 731.10 Td (date. ) Tj ET Q q 0 0 0 rg BT 569.34 731.10 Td (A) Tj ET Q q 0 0 0 rg BT 576.01 731.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 719.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 81.62 719.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 113.92 719.10 Td (of ) Tj ET Q q 0 0 0 rg BT 125.67 719.10 Td (a ) Tj ET Q q 0 0 0 rg BT 133.52 719.10 Td (product’) Tj ET Q q 0 0 0 rg BT 166.84 719.10 Td (s ) Tj ET Q q 0 0 0 rg BT 174.14 719.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 201.99 719.10 Td (life, ) Tj ET Q q 0 0 0 rg BT 221.23 719.10 Td (however) Tj ET Q q 0 0 0 rg BT 255.26 719.10 Td (, ) Tj ET Q q 0 0 0 rg BT 261.17 719.10 Td (is ) Tj ET Q q 0 0 0 rg BT 271.25 719.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 289.11 719.10 Td (during ) Tj ET Q q 0 0 0 rg BT 318.63 719.10 Td (the ) Tj ET Q q 0 0 0 rg BT 334.26 719.10 Td (time ) Tj ET Q q 0 0 0 rg BT 355.45 719.10 Td (it ) Tj ET Q q 0 0 0 rg BT 364.41 719.10 Td (takes ) Tj ET Q q 0 0 0 rg BT 388.37 719.10 Td (an ) Tj ET Q q 0 0 0 rg BT 401.22 719.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 446.85 719.10 Td (company ) Tj ET Q q 0 0 0 rg BT 486.92 719.10 Td (to ) Tj ET Q q 0 0 0 rg BT 498.11 719.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 533.17 719.10 Td (and ) Tj ET Q q 0 0 0 rg BT 551.02 719.10 Td (obtain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 707.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.03 707.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 115.95 707.10 Td (of ) Tj ET Q q 0 0 0 rg BT 126.21 707.10 Td (a ) Tj ET Q q 0 0 0 rg BT 132.59 707.10 Td (new ) Tj ET Q q 0 0 0 rg BT 151.18 707.10 Td (drug. ) Tj ET Q q 0 0 0 rg BT 173.52 707.10 Td (As ) Tj ET Q q 0 0 0 rg BT 186.57 707.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 244.05 707.10 Td (at ) Tj ET Q q 0 0 0 rg BT 253.20 707.10 Td (least ) Tj ET Q q 0 0 0 rg BT 273.46 707.10 Td (in ) Tj ET Q q 0 0 0 rg BT 283.17 707.10 Td (part ) Tj ET Q q 0 0 0 rg BT 300.65 707.10 Td (for ) Tj ET Q q 0 0 0 rg BT 314.25 707.10 Td (the ) Tj ET Q q 0 0 0 rg BT 328.40 707.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 344.78 707.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 371.15 707.10 Td (term ) Tj ET Q q 0 0 0 rg BT 391.41 707.10 Td (due ) Tj ET Q q 0 0 0 rg BT 407.79 707.10 Td (to ) Tj ET Q q 0 0 0 rg BT 417.50 707.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 460.53 707.10 Td (review ) Tj ET Q q 0 0 0 rg BT 489.67 707.10 Td (periods, ) Tj ET Q q 0 0 0 rg BT 523.54 707.10 Td (the ) Tj ET Q q 0 0 0 rg BT 537.70 707.10 Td (innovator ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 695.10 Td (may) Tj ET Q q 0 0 0 rg BT 52.57 695.10 Td (, ) Tj ET Q q 0 0 0 rg BT 57.16 695.10 Td (depending ) Tj ET Q q 0 0 0 rg BT 100.90 695.10 Td (on ) Tj ET Q q 0 0 0 rg BT 112.99 695.10 Td (a ) Tj ET Q q 0 0 0 rg BT 119.52 695.10 Td (number ) Tj ET Q q 0 0 0 rg BT 152.15 695.10 Td (of ) Tj ET Q q 0 0 0 rg BT 162.57 695.10 Td (factors, ) Tj ET Q q 0 0 0 rg BT 194.37 695.10 Td (apply ) Tj ET Q q 0 0 0 rg BT 218.67 695.10 Td (to ) Tj ET Q q 0 0 0 rg BT 228.54 695.10 Td (the ) Tj ET Q q 0 0 0 rg BT 242.85 695.10 Td (government ) Tj ET Q q 0 0 0 rg BT 292.70 695.10 Td (to ) Tj ET Q q 0 0 0 rg BT 302.57 695.10 Td (restore ) Tj ET Q q 0 0 0 rg BT 331.86 695.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 348.40 695.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 374.92 695.10 Td (term ) Tj ET Q q 0 0 0 rg BT 395.33 695.10 Td (by ) Tj ET Q q 0 0 0 rg BT 407.42 695.10 Td (extending ) Tj ET Q q 0 0 0 rg BT 448.95 695.10 Td (the ) Tj ET Q q 0 0 0 rg BT 463.25 695.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 505.88 695.10 Td (date ) Tj ET Q q 0 0 0 rg BT 524.63 695.10 Td (of ) Tj ET Q q 0 0 0 rg BT 535.05 695.10 Td (one ) Tj ET Q q 0 0 0 rg BT 551.57 695.10 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 683.10 Td (up ) Tj ET Q q 0 0 0 rg BT 48.50 683.10 Td (to ) Tj ET Q q 0 0 0 rg BT 58.79 683.10 Td (a ) Tj ET Q q 0 0 0 rg BT 65.73 683.10 Td (maximum ) Tj ET Q q 0 0 0 rg BT 108.78 683.10 Td (term ) Tj ET Q q 0 0 0 rg BT 129.61 683.10 Td (of ) Tj ET Q q 0 0 0 rg BT 140.45 683.10 Td (five ) Tj ET Q q 0 0 0 rg BT 158.50 683.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 184.60 683.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 222.65 683.10 Td (that ) Tj ET Q q 0 0 0 rg BT 240.15 683.10 Td (the ) Tj ET Q q 0 0 0 rg BT 254.87 683.10 Td (extension ) Tj ET Q q 0 0 0 rg BT 295.70 683.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 324.86 683.10 Td (cause ) Tj ET Q q 0 0 0 rg BT 349.57 683.10 Td (the ) Tj ET Q q 0 0 0 rg BT 364.29 683.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 391.23 683.10 Td (to ) Tj ET Q q 0 0 0 rg BT 401.51 683.10 Td (be ) Tj ET Q q 0 0 0 rg BT 413.45 683.10 Td (in ) Tj ET Q q 0 0 0 rg BT 423.74 683.10 Td (ef) Tj ET Q q 0 0 0 rg BT 431.32 683.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 448.81 683.10 Td (for ) Tj ET Q q 0 0 0 rg BT 462.98 683.10 Td (more ) Tj ET Q q 0 0 0 rg BT 486.03 683.10 Td (than ) Tj ET Q q 0 0 0 rg BT 505.75 683.10 Td (14 ) Tj ET Q q 0 0 0 rg BT 518.25 683.10 Td (years ) Tj ET Q q 0 0 0 rg BT 541.85 683.10 Td (from ) Tj ET Q q 0 0 0 rg BT 563.80 683.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 671.10 Td (date ) Tj ET Q q 0 0 0 rg BT 55.16 671.10 Td (of ) Tj ET Q q 0 0 0 rg BT 65.99 671.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 86.82 671.10 Td (approval.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 647.10 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 647.10 Td ( ) Tj ET Q q 0 0 0 rg BT 45.67 647.10 Td (company ) Tj ET Q q 0 0 0 rg BT 85.32 647.10 Td (seeking ) Tj ET Q q 0 0 0 rg BT 118.86 647.10 Td (to ) Tj ET Q q 0 0 0 rg BT 129.63 647.10 Td (market ) Tj ET Q q 0 0 0 rg BT 160.39 647.10 Td (an ) Tj ET Q q 0 0 0 rg BT 172.83 647.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 218.03 647.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 282.10 647.10 Td (in ) Tj ET Q q 0 0 0 rg BT 292.88 647.10 Td (the ) Tj ET Q q 0 0 0 rg BT 308.09 647.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 328.87 647.10 Td (must ) Tj ET Q q 0 0 0 rg BT 351.31 647.10 Td (submit ) Tj ET Q q 0 0 0 rg BT 381.53 647.10 Td (a ) Tj ET Q q 0 0 0 rg BT 388.97 647.10 Td (complete ) Tj ET Q q 0 0 0 rg BT 428.61 647.10 Td (set ) Tj ET Q q 0 0 0 rg BT 442.72 647.10 Td (of ) Tj ET Q q 0 0 0 rg BT 454.04 647.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 480.92 647.10 Td (and ) Tj ET Q q 0 0 0 rg BT 498.35 647.10 Td (ef) Tj ET Q q 0 0 0 rg BT 505.94 647.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 533.36 647.10 Td (data ) Tj ET Q q 0 0 0 rg BT 553.01 647.10 Td (to ) Tj ET Q q 0 0 0 rg BT 563.78 647.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 635.10 Td (FDA. ) Tj ET Q q 0 0 0 rg BT 61.09 635.10 Td (If ) Tj ET Q q 0 0 0 rg BT 70.33 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 85.14 635.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 129.93 635.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 193.59 635.10 Td (is ) Tj ET Q q 0 0 0 rg BT 202.84 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 209.87 635.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 248.54 635.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 284.17 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 298.97 635.10 Td (company ) Tj ET Q q 0 0 0 rg BT 338.21 635.10 Td (files ) Tj ET Q q 0 0 0 rg BT 358.01 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 365.04 635.10 Td (NDA. ) Tj ET Q q 0 0 0 rg BT 391.79 635.10 Td (If ) Tj ET Q q 0 0 0 rg BT 401.03 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 415.83 635.10 Td (medicine ) Tj ET Q q 0 0 0 rg BT 455.07 635.10 Td (is ) Tj ET Q q 0 0 0 rg BT 464.32 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 471.35 635.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 513.92 635.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 549.55 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 556.57 635.10 Td (BLA) Tj ET Q q 0 0 0 rg BT 576.02 635.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 623.10 Td (is ) Tj ET Q q 0 0 0 rg BT 45.17 623.10 Td (filed. ) Tj ET Q q 0 0 0 rg BT 68.31 623.10 Td (The ) Tj ET Q q 0 0 0 rg BT 86.36 623.10 Td (type ) Tj ET Q q 0 0 0 rg BT 106.08 623.10 Td (of ) Tj ET Q q 0 0 0 rg BT 116.91 623.10 Td (application ) Tj ET Q q 0 0 0 rg BT 163.84 623.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 184.66 623.10 Td (af) Tj ET Q q 0 0 0 rg BT 192.25 623.10 Td (fects ) Tj ET Q q 0 0 0 rg BT 213.63 623.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 257.22 623.10 Td (data ) Tj ET Q q 0 0 0 rg BT 276.38 623.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 319.42 623.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 365.80 623.10 Td (rights.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 597.7669921875 m 111.4541015625 597.7669921875 l s q 0 0 0 rg BT 36.00 599.10 Td (Chemical pr) Tj ET Q q 0 0 0 rg BT 85.35 599.10 Td (oducts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 581.10 Td ( ) Tj ET Q q 0 0 0 rg BT 45.37 581.10 Td (competitor ) Tj ET Q q 0 0 0 rg BT 91.40 581.10 Td (seeking ) Tj ET Q q 0 0 0 rg BT 124.65 581.10 Td (to ) Tj ET Q q 0 0 0 rg BT 135.13 581.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 164.48 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 171.63 581.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 203.75 581.10 Td (substitute ) Tj ET Q q 0 0 0 rg BT 244.79 581.10 Td (of ) Tj ET Q q 0 0 0 rg BT 255.82 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 262.96 581.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 301.75 581.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 346.67 581.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 367.70 581.10 Td (in ) Tj ET Q q 0 0 0 rg BT 378.18 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.10 581.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 413.59 581.10 Td (must ) Tj ET Q q 0 0 0 rg BT 435.74 581.10 Td (file ) Tj ET Q q 0 0 0 rg BT 451.77 581.10 Td (an ) Tj ET Q q 0 0 0 rg BT 463.91 581.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 489.46 581.10 Td ( ) Tj ET Q q 0 0 0 rg BT 492.16 581.10 Td (with ) Tj ET Q q 0 0 0 rg BT 512.64 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 527.56 581.10 Td (FDA. ) Tj ET Q q 0 0 0 rg BT 552.77 581.10 Td (In ) Tj ET Q q 0 0 0 rg BT 563.80 581.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (aNDA, ) Tj ET Q q 0 0 0 rg BT 66.41 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 80.44 569.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 111.67 569.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 166.78 569.10 Td (needs ) Tj ET Q q 0 0 0 rg BT 191.36 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 200.95 569.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 251.63 569.10 Td (only ) Tj ET Q q 0 0 0 rg BT 271.21 569.10 Td (“bioequivalence” ) Tj ET Q q 0 0 0 rg BT 342.43 569.10 Td (between ) Tj ET Q q 0 0 0 rg BT 377.55 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 391.58 569.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 422.81 569.10 Td (substitute ) Tj ET Q q 0 0 0 rg BT 462.96 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 479.20 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 493.23 569.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 532.25 569.10 Td (NDA) Tj ET Q q 0 0 0 rg BT 553.36 569.10 Td ( ) Tj ET Q q 0 0 0 rg BT 555.17 569.10 Td (drug. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 557.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 79.60 557.10 Td ( ) Tj ET Q q 0 0 0 rg BT 82.10 557.10 Td (relies ) Tj ET Q q 0 0 0 rg BT 106.25 557.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 128.75 557.10 Td (the ) Tj ET Q q 0 0 0 rg BT 143.47 557.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 169.85 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 186.79 557.10 Td (ef) Tj ET Q q 0 0 0 rg BT 194.37 557.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 221.30 557.10 Td (data ) Tj ET Q q 0 0 0 rg BT 240.45 557.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 285.17 557.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 306.00 557.10 Td (by ) Tj ET Q q 0 0 0 rg BT 318.50 557.10 Td (the ) Tj ET Q q 0 0 0 rg BT 333.21 557.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 374.04 557.10 Td (in ) Tj ET Q q 0 0 0 rg BT 384.32 557.10 Td (its ) Tj ET Q q 0 0 0 rg BT 396.26 557.10 Td (NDA.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (An ) Tj ET Q q 0 0 0 rg BT 50.91 533.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 91.92 533.10 Td (company ) Tj ET Q q 0 0 0 rg BT 131.26 533.10 Td (is ) Tj ET Q q 0 0 0 rg BT 140.61 533.10 Td (required ) Tj ET Q q 0 0 0 rg BT 176.62 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 187.08 533.10 Td (list ) Tj ET Q q 0 0 0 rg BT 201.99 533.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 231.88 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 242.89 533.10 Td (its ) Tj ET Q q 0 0 0 rg BT 255.03 533.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 286.04 533.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 323.71 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 338.61 533.10 Td (medicine ) Tj ET Q q 0 0 0 rg BT 377.95 533.10 Td (with ) Tj ET Q q 0 0 0 rg BT 398.41 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 413.31 533.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 432.77 533.10 Td ( ) Tj ET Q q 0 0 0 rg BT 435.45 533.10 Td (in ) Tj ET Q q 0 0 0 rg BT 445.92 533.10 Td (what ) Tj ET Q q 0 0 0 rg BT 468.04 533.10 Td (is ) Tj ET Q q 0 0 0 rg BT 477.40 533.10 Td (commonly ) Tj ET Q q 0 0 0 rg BT 522.86 533.10 Td (known ) Tj ET Q q 0 0 0 rg BT 552.76 533.10 Td (as ) Tj ET Q q 0 0 0 rg BT 563.78 533.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (Orange ) Tj ET Q q 0 0 0 rg BT 68.09 521.10 Td (Book. ) Tj ET Q q 0 0 0 rg BT 94.34 521.10 Td (Absent ) Tj ET Q q 0 0 0 rg BT 125.34 521.10 Td (a ) Tj ET Q q 0 0 0 rg BT 132.44 521.10 Td (successful ) Tj ET Q q 0 0 0 rg BT 176.21 521.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 203.31 521.10 Td (challenge, ) Tj ET Q q 0 0 0 rg BT 246.78 521.10 Td (the ) Tj ET Q q 0 0 0 rg BT 261.67 521.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 281.12 521.10 Td ( ) Tj ET Q q 0 0 0 rg BT 283.79 521.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 313.11 521.10 Td (approve ) Tj ET Q q 0 0 0 rg BT 347.98 521.10 Td (an ) Tj ET Q q 0 0 0 rg BT 360.08 521.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 385.64 521.10 Td ( ) Tj ET Q q 0 0 0 rg BT 388.30 521.10 Td (until ) Tj ET Q q 0 0 0 rg BT 409.30 521.10 Td (after ) Tj ET Q q 0 0 0 rg BT 430.28 521.10 Td (the ) Tj ET Q q 0 0 0 rg BT 445.17 521.10 Td (innovator) Tj ET Q q 0 0 0 rg BT 483.86 521.10 Td (’) Tj ET Q q 0 0 0 rg BT 486.64 521.10 Td (s ) Tj ET Q q 0 0 0 rg BT 493.20 521.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 517.53 521.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 548.52 521.10 Td (expire. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (However) Tj ET Q q 0 0 0 rg BT 72.25 509.10 Td (, ) Tj ET Q q 0 0 0 rg BT 77.53 509.10 Td (after ) Tj ET Q q 0 0 0 rg BT 98.63 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 113.62 509.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 154.73 509.10 Td (has ) Tj ET Q q 0 0 0 rg BT 170.84 509.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 210.82 509.10 Td (its ) Tj ET Q q 0 0 0 rg BT 223.05 509.10 Td (product ) Tj ET Q q 0 0 0 rg BT 256.38 509.10 Td (for ) Tj ET Q q 0 0 0 rg BT 270.82 509.10 Td (four ) Tj ET Q q 0 0 0 rg BT 290.26 509.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 316.64 509.10 Td (a ) Tj ET Q q 0 0 0 rg BT 323.86 509.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 356.07 509.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 412.15 509.10 Td (may ) Tj ET Q q 0 0 0 rg BT 432.15 509.10 Td (file ) Tj ET Q q 0 0 0 rg BT 448.25 509.10 Td (an ) Tj ET Q q 0 0 0 rg BT 460.47 509.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 486.02 509.10 Td ( ) Tj ET Q q 0 0 0 rg BT 488.80 509.10 Td (and ) Tj ET Q q 0 0 0 rg BT 506.02 509.10 Td (allege ) Tj ET Q q 0 0 0 rg BT 532.67 509.10 Td (that ) Tj ET Q q 0 0 0 rg BT 550.45 509.10 Td (one ) Tj ET Q q 0 0 0 rg BT 567.67 509.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (more ) Tj ET Q q 0 0 0 rg BT 59.06 497.10 Td (of ) Tj ET Q q 0 0 0 rg BT 69.90 497.10 Td (the ) Tj ET Q q 0 0 0 rg BT 84.62 497.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 115.46 497.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 139.63 497.10 Td (in ) Tj ET Q q 0 0 0 rg BT 149.92 497.10 Td (the ) Tj ET Q q 0 0 0 rg BT 164.65 497.10 Td (Orange ) Tj ET Q q 0 0 0 rg BT 196.59 497.10 Td (Book ) Tj ET Q q 0 0 0 rg BT 220.77 497.10 Td (under ) Tj ET Q q 0 0 0 rg BT 246.04 497.10 Td (an ) Tj ET Q q 0 0 0 rg BT 257.99 497.10 Td (innovator) Tj ET Q q 0 0 0 rg BT 296.69 497.10 Td (’) Tj ET Q q 0 0 0 rg BT 299.47 497.10 Td (s ) Tj ET Q q 0 0 0 rg BT 305.87 497.10 Td (NDA) Tj ET Q q 0 0 0 rg BT 326.98 497.10 Td ( ) Tj ET Q q 0 0 0 rg BT 329.49 497.10 Td (is ) Tj ET Q q 0 0 0 rg BT 338.67 497.10 Td (either ) Tj ET Q q 0 0 0 rg BT 363.94 497.10 Td (invalid ) Tj ET Q q 0 0 0 rg BT 394.23 497.10 Td (or ) Tj ET Q q 0 0 0 rg BT 405.07 497.10 Td (not ) Tj ET Q q 0 0 0 rg BT 420.36 497.10 Td (infringed. ) Tj ET Q q 0 0 0 rg BT 461.84 497.10 Td (This ) Tj ET Q q 0 0 0 rg BT 482.13 497.10 Td (allegation ) Tj ET Q q 0 0 0 rg BT 524.07 497.10 Td (is ) Tj ET Q q 0 0 0 rg BT 533.25 497.10 Td (commonly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (known ) Tj ET Q q 0 0 0 rg BT 66.40 485.10 Td (as ) Tj ET Q q 0 0 0 rg BT 77.92 485.10 Td (a ) Tj ET Q q 0 0 0 rg BT 85.54 485.10 Td (Paragraph ) Tj ET Q q 0 0 0 rg BT 129.26 485.10 Td (IV) Tj ET Q q 0 0 0 rg BT 139.63 485.10 Td ( ) Tj ET Q q 0 0 0 rg BT 142.81 485.10 Td (certification. ) Tj ET Q q 0 0 0 rg BT 196.57 485.10 Td (The ) Tj ET Q q 0 0 0 rg BT 215.30 485.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 256.81 485.10 Td (then ) Tj ET Q q 0 0 0 rg BT 277.21 485.10 Td (must ) Tj ET Q q 0 0 0 rg BT 299.84 485.10 Td (decide ) Tj ET Q q 0 0 0 rg BT 329.11 485.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 364.50 485.10 Td (to ) Tj ET Q q 0 0 0 rg BT 375.46 485.10 Td (file ) Tj ET Q q 0 0 0 rg BT 391.97 485.10 Td (a ) Tj ET Q q 0 0 0 rg BT 399.59 485.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 427.21 485.10 Td (infringement ) Tj ET Q q 0 0 0 rg BT 482.04 485.10 Td (suit ) Tj ET Q q 0 0 0 rg BT 499.67 485.10 Td (against ) Tj ET Q q 0 0 0 rg BT 531.18 485.10 Td (the ) Tj ET Q q 0 0 0 rg BT 546.58 485.10 Td (generic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (manufacturer) Tj ET Q q 0 0 0 rg BT 88.75 473.10 Td (. ) Tj ET Q q 0 0 0 rg BT 94.32 473.10 Td (From ) Tj ET Q q 0 0 0 rg BT 119.06 473.10 Td (time ) Tj ET Q q 0 0 0 rg BT 139.90 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 150.75 473.10 Td (time, ) Tj ET Q q 0 0 0 rg BT 174.10 473.10 Td (aNDAs, ) Tj ET Q q 0 0 0 rg BT 209.66 473.10 Td (including ) Tj ET Q q 0 0 0 rg BT 250.50 473.10 Td (Paragraph ) Tj ET Q q 0 0 0 rg BT 294.11 473.10 Td (IV) Tj ET Q q 0 0 0 rg BT 304.48 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 307.55 473.10 Td (certifications, ) Tj ET Q q 0 0 0 rg BT 365.32 473.10 Td (are ) Tj ET Q q 0 0 0 rg BT 380.60 473.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 401.99 473.10 Td (with ) Tj ET Q q 0 0 0 rg BT 422.84 473.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 454.23 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 465.08 473.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 495.35 473.10 Td (of ) Tj ET Q q 0 0 0 rg BT 506.75 473.10 Td (our ) Tj ET Q q 0 0 0 rg BT 523.15 473.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 562.94 473.10 Td (W) Tj ET Q q 0 0 0 rg BT 571.57 473.10 Td (e ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (evaluate ) Tj ET Q q 0 0 0 rg BT 71.17 461.10 Td (these ) Tj ET Q q 0 0 0 rg BT 93.58 461.10 Td (aNDAs ) Tj ET Q q 0 0 0 rg BT 125.43 461.10 Td (on ) Tj ET Q q 0 0 0 rg BT 137.29 461.10 Td (a ) Tj ET Q q 0 0 0 rg BT 143.59 461.10 Td (case-by-case ) Tj ET Q q 0 0 0 rg BT 196.52 461.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 218.38 461.10 Td (and, ) Tj ET Q q 0 0 0 rg BT 237.18 461.10 Td (where ) Tj ET Q q 0 0 0 rg BT 263.47 461.10 Td (warranted, ) Tj ET Q q 0 0 0 rg BT 307.80 461.10 Td (file ) Tj ET Q q 0 0 0 rg BT 322.99 461.10 Td (suit ) Tj ET Q q 0 0 0 rg BT 339.29 461.10 Td (against ) Tj ET Q q 0 0 0 rg BT 369.48 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 383.55 461.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 414.84 461.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 470.00 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 479.64 461.10 Td (protect ) Tj ET Q q 0 0 0 rg BT 509.26 461.10 Td (our ) Tj ET Q q 0 0 0 rg BT 524.45 461.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 550.74 461.10 Td (rights.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.69 437.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 81.82 437.10 Td (to ) Tj ET Q q 0 0 0 rg BT 91.96 437.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 118.75 437.10 Td (protection, ) Tj ET Q q 0 0 0 rg BT 164.15 437.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 193.71 437.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 238.28 437.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 301.71 437.10 Td (products ) Tj ET Q q 0 0 0 rg BT 338.51 437.10 Td (can ) Tj ET Q q 0 0 0 rg BT 354.75 437.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 385.97 437.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 417.76 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 428.45 437.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 471.90 437.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 515.14 437.10 Td (. ) Tj ET Q q 0 0 0 rg BT 519.47 437.10 Td (A) Tj ET Q q 0 0 0 rg BT 526.14 437.10 Td ( ) Tj ET Q q 0 0 0 rg BT 528.50 437.10 Td (NDA) Tj ET Q q 0 0 0 rg BT 549.62 437.10 Td ( ) Tj ET Q q 0 0 0 rg BT 551.97 437.10 Td (that ) Tj ET Q q 0 0 0 rg BT 569.33 437.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (designated ) Tj ET Q q 0 0 0 rg BT 80.91 425.10 Td (as ) Tj ET Q q 0 0 0 rg BT 91.40 425.10 Td (an ) Tj ET Q q 0 0 0 rg BT 102.98 425.10 Td (orphan ) Tj ET Q q 0 0 0 rg BT 132.90 425.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 153.39 425.10 Td (can ) Tj ET Q q 0 0 0 rg BT 169.41 425.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 200.43 425.10 Td (seven ) Tj ET Q q 0 0 0 rg BT 225.35 425.10 Td (years ) Tj ET Q q 0 0 0 rg BT 248.60 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 259.08 425.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 305.11 425.10 Td (for ) Tj ET Q q 0 0 0 rg BT 318.92 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 333.29 425.10 Td (orphan ) Tj ET Q q 0 0 0 rg BT 363.21 425.10 Td (indication. ) Tj ET Q q 0 0 0 rg BT 407.85 425.10 Td (During ) Tj ET Q q 0 0 0 rg BT 438.33 425.10 Td (this ) Tj ET Q q 0 0 0 rg BT 454.93 425.10 Td (time ) Tj ET Q q 0 0 0 rg BT 474.85 425.10 Td (period, ) Tj ET Q q 0 0 0 rg BT 505.05 425.10 Td (neither ) Tj ET Q q 0 0 0 rg BT 534.96 425.10 Td (NDAs ) Tj ET Q q 0 0 0 rg BT 562.67 425.10 Td (nor ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (aNDAs ) Tj ET Q q 0 0 0 rg BT 67.79 413.10 Td (for ) Tj ET Q q 0 0 0 rg BT 81.25 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 95.27 413.10 Td (same ) Tj ET Q q 0 0 0 rg BT 117.62 413.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 137.75 413.10 Td (product ) Tj ET Q q 0 0 0 rg BT 170.09 413.10 Td (can ) Tj ET Q q 0 0 0 rg BT 185.77 413.10 Td (be ) Tj ET Q q 0 0 0 rg BT 197.01 413.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 236.01 413.10 Td (for ) Tj ET Q q 0 0 0 rg BT 249.47 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 263.49 413.10 Td (same ) Tj ET Q q 0 0 0 rg BT 285.83 413.10 Td (orphan ) Tj ET Q q 0 0 0 rg BT 315.40 413.10 Td (use. ) Tj ET Q q 0 0 0 rg BT 332.63 413.10 Td (A) Tj ET Q q 0 0 0 rg BT 339.30 413.10 Td ( ) Tj ET Q q 0 0 0 rg BT 341.10 413.10 Td (company ) Tj ET Q q 0 0 0 rg BT 379.56 413.10 Td (may ) Tj ET Q q 0 0 0 rg BT 398.57 413.10 Td (also ) Tj ET Q q 0 0 0 rg BT 416.48 413.10 Td (earn ) Tj ET Q q 0 0 0 rg BT 435.49 413.10 Td (six ) Tj ET Q q 0 0 0 rg BT 448.96 413.10 Td (months ) Tj ET Q q 0 0 0 rg BT 480.21 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 490.33 413.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 532.12 413.10 Td (exclusivity ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (for ) Tj ET Q q 0 0 0 rg BT 49.67 401.10 Td (a ) Tj ET Q q 0 0 0 rg BT 56.12 401.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 76.45 401.10 Td (where ) Tj ET Q q 0 0 0 rg BT 102.89 401.10 Td (specific ) Tj ET Q q 0 0 0 rg BT 135.99 401.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 167.43 401.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 197.22 401.10 Td (are ) Tj ET Q q 0 0 0 rg BT 211.43 401.10 Td (conducted ) Tj ET Q q 0 0 0 rg BT 254.53 401.10 Td (at ) Tj ET Q q 0 0 0 rg BT 263.76 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 277.98 401.10 Td (written ) Tj ET Q q 0 0 0 rg BT 308.32 401.10 Td (request ) Tj ET Q q 0 0 0 rg BT 339.20 401.10 Td (of ) Tj ET Q q 0 0 0 rg BT 349.54 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.77 401.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 383.22 401.10 Td ( ) Tj ET Q q 0 0 0 rg BT 385.23 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 395.01 401.10 Td (study ) Tj ET Q q 0 0 0 rg BT 418.69 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 432.92 401.10 Td (use ) Tj ET Q q 0 0 0 rg BT 448.26 401.10 Td (of ) Tj ET Q q 0 0 0 rg BT 458.59 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 472.82 401.10 Td (medicine ) Tj ET Q q 0 0 0 rg BT 511.48 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 521.26 401.10 Td (treat ) Tj ET Q q 0 0 0 rg BT 541.04 401.10 Td (pediatric ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (patients, ) Tj ET Q q 0 0 0 rg BT 72.10 389.10 Td (and ) Tj ET Q q 0 0 0 rg BT 89.04 389.10 Td (submission ) Tj ET Q q 0 0 0 rg BT 136.55 389.10 Td (to ) Tj ET Q q 0 0 0 rg BT 146.83 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 161.55 389.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 181.00 389.10 Td ( ) Tj ET Q q 0 0 0 rg BT 183.50 389.10 Td (is ) Tj ET Q q 0 0 0 rg BT 192.67 389.10 Td (made ) Tj ET Q q 0 0 0 rg BT 216.83 389.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 238.76 389.10 Td (to ) Tj ET Q q 0 0 0 rg BT 249.04 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 263.76 389.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 281.82 389.10 Td (of ) Tj ET Q q 0 0 0 rg BT 292.65 389.10 Td (basic ) Tj ET Q q 0 0 0 rg BT 315.70 389.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 358.93 389.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 80.27 365.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 120.09 365.10 Td (under ) Tj ET Q q 0 0 0 rg BT 145.47 365.10 Td (a ) Tj ET Q q 0 0 0 rg BT 152.52 365.10 Td (NDA) Tj ET Q q 0 0 0 rg BT 173.63 365.10 Td ( ) Tj ET Q q 0 0 0 rg BT 176.24 365.10 Td (can ) Tj ET Q q 0 0 0 rg BT 192.73 365.10 Td (also ) Tj ET Q q 0 0 0 rg BT 211.45 365.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 242.93 365.10 Td (several ) Tj ET Q q 0 0 0 rg BT 273.86 365.10 Td (types ) Tj ET Q q 0 0 0 rg BT 297.58 365.10 Td (of ) Tj ET Q q 0 0 0 rg BT 308.52 365.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 352.23 365.10 Td (data ) Tj ET Q q 0 0 0 rg BT 371.49 365.10 Td (protection. ) Tj ET Q q 0 0 0 rg BT 416.57 365.10 Td (An ) Tj ET Q q 0 0 0 rg BT 431.40 365.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 476.23 365.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 514.93 365.10 Td (pharmaceutical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (product ) Tj ET Q q 0 0 0 rg BT 68.83 353.10 Td (is ) Tj ET Q q 0 0 0 rg BT 77.78 353.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 110.04 353.10 Td (to ) Tj ET Q q 0 0 0 rg BT 120.10 353.10 Td (five ) Tj ET Q q 0 0 0 rg BT 137.93 353.10 Td (years ) Tj ET Q q 0 0 0 rg BT 161.31 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 171.92 353.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 215.29 353.10 Td (data ) Tj ET Q q 0 0 0 rg BT 234.22 353.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 277.04 353.10 Td (in ) Tj ET Q q 0 0 0 rg BT 287.10 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 301.60 353.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 324.16 353.10 Td (during ) Tj ET Q q 0 0 0 rg BT 352.55 353.10 Td (which ) Tj ET Q q 0 0 0 rg BT 379.27 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.76 353.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 413.22 353.10 Td ( ) Tj ET Q q 0 0 0 rg BT 415.50 353.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 444.43 353.10 Td (approve ) Tj ET Q q 0 0 0 rg BT 478.92 353.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 510.62 353.10 Td (substitutes. ) Tj ET Q q 0 0 0 rg BT 557.63 353.10 Td (If ) Tj ET Q q 0 0 0 rg BT 566.56 353.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (innovator) Tj ET Q q 0 0 0 rg BT 74.70 341.10 Td (’) Tj ET Q q 0 0 0 rg BT 77.47 341.10 Td (s ) Tj ET Q q 0 0 0 rg BT 84.53 341.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 112.12 341.10 Td (is ) Tj ET Q q 0 0 0 rg BT 121.95 341.10 Td (challenged, ) Tj ET Q q 0 0 0 rg BT 170.92 341.10 Td (as ) Tj ET Q q 0 0 0 rg BT 182.41 341.10 Td (described ) Tj ET Q q 0 0 0 rg BT 223.88 341.10 Td (above, ) Tj ET Q q 0 0 0 rg BT 253.42 341.10 Td (a ) Tj ET Q q 0 0 0 rg BT 261.01 341.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 293.60 341.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 350.06 341.10 Td (may ) Tj ET Q q 0 0 0 rg BT 370.43 341.10 Td (file ) Tj ET Q q 0 0 0 rg BT 386.92 341.10 Td (its ) Tj ET Q q 0 0 0 rg BT 399.53 341.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 425.08 341.10 Td ( ) Tj ET Q q 0 0 0 rg BT 428.24 341.10 Td (after ) Tj ET Q q 0 0 0 rg BT 449.71 341.10 Td (the ) Tj ET Q q 0 0 0 rg BT 465.09 341.10 Td (fourth ) Tj ET Q q 0 0 0 rg BT 492.68 341.10 Td (year ) Tj ET Q q 0 0 0 rg BT 513.05 341.10 Td (of ) Tj ET Q q 0 0 0 rg BT 524.54 341.10 Td (the ) Tj ET Q q 0 0 0 rg BT 539.92 341.10 Td (five-year ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.37 329.10 Td (data ) Tj ET Q q 0 0 0 rg BT 98.30 329.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 141.12 329.10 Td (period. ) Tj ET Q q 0 0 0 rg BT 170.94 329.10 Td (A) Tj ET Q q 0 0 0 rg BT 177.61 329.10 Td ( ) Tj ET Q q 0 0 0 rg BT 179.89 329.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 243.24 329.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 263.85 329.10 Td (product ) Tj ET Q q 0 0 0 rg BT 296.67 329.10 Td (that ) Tj ET Q q 0 0 0 rg BT 313.94 329.10 Td (contains ) Tj ET Q q 0 0 0 rg BT 349.54 329.10 Td (an ) Tj ET Q q 0 0 0 rg BT 361.26 329.10 Td (active ) Tj ET Q q 0 0 0 rg BT 387.41 329.10 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 430.23 329.10 Td (that ) Tj ET Q q 0 0 0 rg BT 447.50 329.10 Td (has ) Tj ET Q q 0 0 0 rg BT 463.11 329.10 Td (been ) Tj ET Q q 0 0 0 rg BT 484.26 329.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 528.75 329.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 568.24 329.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (an ) Tj ET Q q 0 0 0 rg BT 48.24 317.10 Td (NDA, ) Tj ET Q q 0 0 0 rg BT 75.21 317.10 Td (but ) Tj ET Q q 0 0 0 rg BT 90.79 317.10 Td (is ) Tj ET Q q 0 0 0 rg BT 100.27 317.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 140.28 317.10 Td (in ) Tj ET Q q 0 0 0 rg BT 150.86 317.10 Td (a ) Tj ET Q q 0 0 0 rg BT 158.10 317.10 Td (new ) Tj ET Q q 0 0 0 rg BT 177.57 317.10 Td (formulation, ) Tj ET Q q 0 0 0 rg BT 230.09 317.10 Td (but ) Tj ET Q q 0 0 0 rg BT 245.67 317.10 Td (not ) Tj ET Q q 0 0 0 rg BT 261.25 317.10 Td (for ) Tj ET Q q 0 0 0 rg BT 275.71 317.10 Td (the ) Tj ET Q q 0 0 0 rg BT 290.74 317.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 311.87 317.10 Td (itself, ) Tj ET Q q 0 0 0 rg BT 337.17 317.10 Td (or ) Tj ET Q q 0 0 0 rg BT 348.30 317.10 Td (for ) Tj ET Q q 0 0 0 rg BT 362.77 317.10 Td (a ) Tj ET Q q 0 0 0 rg BT 370.01 317.10 Td (new ) Tj ET Q q 0 0 0 rg BT 389.48 317.10 Td (indication ) Tj ET Q q 0 0 0 rg BT 432.27 317.10 Td (on ) Tj ET Q q 0 0 0 rg BT 445.07 317.10 Td (the ) Tj ET Q q 0 0 0 rg BT 460.09 317.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 482.90 317.10 Td (of ) Tj ET Q q 0 0 0 rg BT 494.03 317.10 Td (new ) Tj ET Q q 0 0 0 rg BT 513.50 317.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 545.73 317.10 Td (studies, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (may ) Tj ET Q q 0 0 0 rg BT 55.72 305.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 87.08 305.10 Td (three ) Tj ET Q q 0 0 0 rg BT 109.56 305.10 Td (years ) Tj ET Q q 0 0 0 rg BT 133.16 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 143.99 305.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 187.59 305.10 Td (data ) Tj ET Q q 0 0 0 rg BT 206.74 305.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 249.78 305.10 Td (for ) Tj ET Q q 0 0 0 rg BT 263.94 305.10 Td (that ) Tj ET Q q 0 0 0 rg BT 281.44 305.10 Td (formulation ) Tj ET Q q 0 0 0 rg BT 331.15 305.10 Td (or ) Tj ET Q q 0 0 0 rg BT 341.98 305.10 Td (indication.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 279.7669921875 m 107.0107421875 279.7669921875 l s q 0 0 0 rg BT 36.00 281.10 Td (Biologic pr) Tj ET Q q 0 0 0 rg BT 80.90 281.10 Td (oducts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 263.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.37 263.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.97 263.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 118.87 263.10 Td (legislation ) Tj ET Q q 0 0 0 rg BT 163.35 263.10 Td (enacted ) Tj ET Q q 0 0 0 rg BT 196.71 263.10 Td (in ) Tj ET Q q 0 0 0 rg BT 207.31 263.10 Td (2010 ) Tj ET Q q 0 0 0 rg BT 230.13 263.10 Td (created ) Tj ET Q q 0 0 0 rg BT 261.81 263.10 Td (an ) Tj ET Q q 0 0 0 rg BT 274.07 263.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 311.88 263.10 Td (pathway ) Tj ET Q q 0 0 0 rg BT 348.58 263.10 Td (for ) Tj ET Q q 0 0 0 rg BT 363.06 263.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 406.43 263.10 Td (versions ) Tj ET Q q 0 0 0 rg BT 442.58 263.10 Td (of ) Tj ET Q q 0 0 0 rg BT 453.73 263.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 498.77 263.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 541.58 263.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 251.10 Td (that ) Tj ET Q q 0 0 0 rg BT 54.23 251.10 Td (did ) Tj ET Q q 0 0 0 rg BT 70.25 251.10 Td (not ) Tj ET Q q 0 0 0 rg BT 86.26 251.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 131.71 251.10 Td (exist. ) Tj ET Q q 0 0 0 rg BT 156.34 251.10 Td (Prior ) Tj ET Q q 0 0 0 rg BT 179.57 251.10 Td (to ) Tj ET Q q 0 0 0 rg BT 190.59 251.10 Td (that ) Tj ET Q q 0 0 0 rg BT 208.82 251.10 Td (time, ) Tj ET Q q 0 0 0 rg BT 232.33 251.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 277.78 251.10 Td (biologics ) Tj ET Q q 0 0 0 rg BT 317.68 251.10 Td (had ) Tj ET Q q 0 0 0 rg BT 335.35 251.10 Td (essentially ) Tj ET Q q 0 0 0 rg BT 380.80 251.10 Td (unlimited ) Tj ET Q q 0 0 0 rg BT 422.37 251.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 466.70 251.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 509.93 251.10 Td (. ) Tj ET Q q 0 0 0 rg BT 515.67 251.10 Td (Under ) Tj ET Q q 0 0 0 rg BT 543.89 251.10 Td (the ) Tj ET Q q 0 0 0 rg BT 559.35 251.10 Td (new ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 239.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.52 239.10 Td (mechanism, ) Tj ET Q q 0 0 0 rg BT 129.99 239.10 Td (the ) Tj ET Q q 0 0 0 rg BT 144.64 239.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 164.09 239.10 Td ( ) Tj ET Q q 0 0 0 rg BT 166.52 239.10 Td (can ) Tj ET Q q 0 0 0 rg BT 182.82 239.10 Td (approve ) Tj ET Q q 0 0 0 rg BT 217.46 239.10 Td (products ) Tj ET Q q 0 0 0 rg BT 254.33 239.10 Td (that ) Tj ET Q q 0 0 0 rg BT 271.75 239.10 Td (are ) Tj ET Q q 0 0 0 rg BT 286.38 239.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 316.59 239.10 Td (to ) Tj ET Q q 0 0 0 rg BT 326.79 239.10 Td (\(but ) Tj ET Q q 0 0 0 rg BT 345.33 239.10 Td (not ) Tj ET Q q 0 0 0 rg BT 360.54 239.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 392.39 239.10 Td (copies ) Tj ET Q q 0 0 0 rg BT 420.36 239.10 Td (of\) ) Tj ET Q q 0 0 0 rg BT 434.45 239.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 479.09 239.10 Td (biologics ) Tj ET Q q 0 0 0 rg BT 518.18 239.10 Td (on ) Tj ET Q q 0 0 0 rg BT 530.61 239.10 Td (the ) Tj ET Q q 0 0 0 rg BT 545.26 239.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 567.69 239.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 227.10 Td (less ) Tj ET Q q 0 0 0 rg BT 53.33 227.10 Td (extensive ) Tj ET Q q 0 0 0 rg BT 93.42 227.10 Td (data ) Tj ET Q q 0 0 0 rg BT 112.40 227.10 Td (than ) Tj ET Q q 0 0 0 rg BT 131.94 227.10 Td (is ) Tj ET Q q 0 0 0 rg BT 140.93 227.10 Td (required ) Tj ET Q q 0 0 0 rg BT 176.58 227.10 Td (by ) Tj ET Q q 0 0 0 rg BT 188.90 227.10 Td (a ) Tj ET Q q 0 0 0 rg BT 195.67 227.10 Td (full ) Tj ET Q q 0 0 0 rg BT 211.88 227.10 Td (BLA. ) Tj ET Q q 0 0 0 rg BT 236.19 227.10 Td (After ) Tj ET Q q 0 0 0 rg BT 259.61 227.10 Td (an ) Tj ET Q q 0 0 0 rg BT 271.38 227.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 312.03 227.10 Td (has ) Tj ET Q q 0 0 0 rg BT 327.68 227.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 367.21 227.10 Td (its ) Tj ET Q q 0 0 0 rg BT 378.99 227.10 Td (product ) Tj ET Q q 0 0 0 rg BT 411.86 227.10 Td (for ) Tj ET Q q 0 0 0 rg BT 425.84 227.10 Td (four ) Tj ET Q q 0 0 0 rg BT 444.83 227.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 470.75 227.10 Td (any ) Tj ET Q q 0 0 0 rg BT 487.52 227.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 543.15 227.10 Td (may ) Tj ET Q q 0 0 0 rg BT 562.69 227.10 Td (file ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 215.10 Td (an ) Tj ET Q q 0 0 0 rg BT 46.86 215.10 Td (application ) Tj ET Q q 0 0 0 rg BT 92.70 215.10 Td (for ) Tj ET Q q 0 0 0 rg BT 105.78 215.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 142.19 215.10 Td (of ) Tj ET Q q 0 0 0 rg BT 151.94 215.10 Td (a ) Tj ET Q q 0 0 0 rg BT 157.79 215.10 Td (“biosimilar” ) Tj ET Q q 0 0 0 rg BT 208.64 215.10 Td (version ) Tj ET Q q 0 0 0 rg BT 239.50 215.10 Td (of ) Tj ET Q q 0 0 0 rg BT 249.24 215.10 Td (the ) Tj ET Q q 0 0 0 rg BT 262.88 215.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 302.62 215.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 337.09 215.10 Td (However) Tj ET Q q 0 0 0 rg BT 373.34 215.10 Td (, ) Tj ET Q q 0 0 0 rg BT 377.26 215.10 Td (although ) Tj ET Q q 0 0 0 rg BT 413.67 215.10 Td (an ) Tj ET Q q 0 0 0 rg BT 424.53 215.10 Td (application ) Tj ET Q q 0 0 0 rg BT 470.38 215.10 Td (for ) Tj ET Q q 0 0 0 rg BT 483.45 215.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 519.86 215.10 Td (of ) Tj ET Q q 0 0 0 rg BT 529.61 215.10 Td (a ) Tj ET Q q 0 0 0 rg BT 535.46 215.10 Td (biosimilar ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 203.10 Td (may ) Tj ET Q q 0 0 0 rg BT 54.96 203.10 Td (be ) Tj ET Q q 0 0 0 rg BT 66.15 203.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 86.22 203.10 Td (four ) Tj ET Q q 0 0 0 rg BT 104.62 203.10 Td (years ) Tj ET Q q 0 0 0 rg BT 127.47 203.10 Td (after ) Tj ET Q q 0 0 0 rg BT 147.53 203.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 184.26 203.10 Td (of ) Tj ET Q q 0 0 0 rg BT 194.33 203.10 Td (the ) Tj ET Q q 0 0 0 rg BT 208.30 203.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 248.37 203.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 283.16 203.10 Td (qualified ) Tj ET Q q 0 0 0 rg BT 320.45 203.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 364.41 203.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 406.14 203.10 Td (products ) Tj ET Q q 0 0 0 rg BT 442.33 203.10 Td (will ) Tj ET Q q 0 0 0 rg BT 459.63 203.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 490.24 203.10 Td (12 ) Tj ET Q q 0 0 0 rg BT 501.98 203.10 Td (years ) Tj ET Q q 0 0 0 rg BT 524.83 203.10 Td (of ) Tj ET Q q 0 0 0 rg BT 534.90 203.10 Td (regulatory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 191.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 79.23 191.10 Td (, ) Tj ET Q q 0 0 0 rg BT 84.34 191.10 Td (meaning ) Tj ET Q q 0 0 0 rg BT 121.38 191.10 Td (that ) Tj ET Q q 0 0 0 rg BT 138.99 191.10 Td (the ) Tj ET Q q 0 0 0 rg BT 153.81 191.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 173.27 191.10 Td ( ) Tj ET Q q 0 0 0 rg BT 175.88 191.10 Td (may ) Tj ET Q q 0 0 0 rg BT 195.70 191.10 Td (not ) Tj ET Q q 0 0 0 rg BT 211.09 191.10 Td (approve ) Tj ET Q q 0 0 0 rg BT 245.90 191.10 Td (a ) Tj ET Q q 0 0 0 rg BT 252.95 191.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 296.11 191.10 Td (version ) Tj ET Q q 0 0 0 rg BT 328.16 191.10 Td (until ) Tj ET Q q 0 0 0 rg BT 349.10 191.10 Td (12 ) Tj ET Q q 0 0 0 rg BT 361.71 191.10 Td (years ) Tj ET Q q 0 0 0 rg BT 385.42 191.10 Td (after ) Tj ET Q q 0 0 0 rg BT 406.34 191.10 Td (the ) Tj ET Q q 0 0 0 rg BT 421.17 191.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 465.99 191.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 508.59 191.10 Td (product ) Tj ET Q q 0 0 0 rg BT 541.75 191.10 Td (was ) Tj ET Q q 0 0 0 rg BT 559.91 191.10 Td (first ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 179.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 75.01 179.10 Td (by ) Tj ET Q q 0 0 0 rg BT 86.82 179.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.84 179.10 Td (FDA. ) Tj ET Q q 0 0 0 rg BT 125.02 179.10 Td (The ) Tj ET Q q 0 0 0 rg BT 142.38 179.10 Td (law ) Tj ET Q q 0 0 0 rg BT 158.62 179.10 Td (also ) Tj ET Q q 0 0 0 rg BT 176.54 179.10 Td (provides ) Tj ET Q q 0 0 0 rg BT 212.78 179.10 Td (a ) Tj ET Q q 0 0 0 rg BT 219.03 179.10 Td (mechanism ) Tj ET Q q 0 0 0 rg BT 266.38 179.10 Td (for ) Tj ET Q q 0 0 0 rg BT 279.84 179.10 Td (innovators ) Tj ET Q q 0 0 0 rg BT 323.87 179.10 Td (to ) Tj ET Q q 0 0 0 rg BT 333.45 179.10 Td (enforce ) Tj ET Q q 0 0 0 rg BT 365.23 179.10 Td (the ) Tj ET Q q 0 0 0 rg BT 379.26 179.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 409.39 179.10 Td (that ) Tj ET Q q 0 0 0 rg BT 426.19 179.10 Td (protect ) Tj ET Q q 0 0 0 rg BT 455.76 179.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 499.78 179.10 Td (biological ) Tj ET Q q 0 0 0 rg BT 541.58 179.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 167.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.18 167.10 Td (for ) Tj ET Q q 0 0 0 rg BT 65.58 167.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 107.88 167.10 Td (applicants ) Tj ET Q q 0 0 0 rg BT 150.16 167.10 Td (to ) Tj ET Q q 0 0 0 rg BT 159.68 167.10 Td (challenge ) Tj ET Q q 0 0 0 rg BT 199.73 167.10 Td (the ) Tj ET Q q 0 0 0 rg BT 213.69 167.10 Td (patents. ) Tj ET Q q 0 0 0 rg BT 246.26 167.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 268.00 167.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 294.18 167.10 Td (litigation ) Tj ET Q q 0 0 0 rg BT 332.03 167.10 Td (may ) Tj ET Q q 0 0 0 rg BT 350.99 167.10 Td (begin ) Tj ET Q q 0 0 0 rg BT 374.95 167.10 Td (as ) Tj ET Q q 0 0 0 rg BT 385.02 167.10 Td (early ) Tj ET Q q 0 0 0 rg BT 406.75 167.10 Td (as ) Tj ET Q q 0 0 0 rg BT 416.82 167.10 Td (four ) Tj ET Q q 0 0 0 rg BT 435.22 167.10 Td (years ) Tj ET Q q 0 0 0 rg BT 458.06 167.10 Td (after ) Tj ET Q q 0 0 0 rg BT 478.12 167.10 Td (the ) Tj ET Q q 0 0 0 rg BT 492.08 167.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 536.03 167.10 Td (biological ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 155.10 Td (product ) Tj ET Q q 0 0 0 rg BT 69.05 155.10 Td (is ) Tj ET Q q 0 0 0 rg BT 78.22 155.10 Td (first ) Tj ET Q q 0 0 0 rg BT 96.83 155.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 136.53 155.10 Td (by ) Tj ET Q q 0 0 0 rg BT 149.03 155.10 Td (the ) Tj ET Q q 0 0 0 rg BT 163.75 155.10 Td (FDA.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 131.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.29 131.10 Td (the ) Tj ET Q q 0 0 0 rg BT 62.46 131.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 85.70 131.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.88 131.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 141.59 131.10 Td (likelihood ) Tj ET Q q 0 0 0 rg BT 185.10 131.10 Td (of ) Tj ET Q q 0 0 0 rg BT 196.39 131.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 228.77 131.10 Td (and ) Tj ET Q q 0 0 0 rg BT 246.17 131.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 289.68 131.10 Td (challenges ) Tj ET Q q 0 0 0 rg BT 334.84 131.10 Td (to ) Tj ET Q q 0 0 0 rg BT 345.57 131.10 Td (innovators’) Tj ET Q q 0 0 0 rg BT 390.38 131.10 Td ( ) Tj ET Q q 0 0 0 rg BT 393.34 131.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 440.72 131.10 Td (property ) Tj ET Q q 0 0 0 rg BT 477.55 131.10 Td (has ) Tj ET Q q 0 0 0 rg BT 493.84 131.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 534.55 131.10 Td (the ) Tj ET Q q 0 0 0 rg BT 549.73 131.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 567.69 131.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 119.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 53.79 119.10 Td (of ) Tj ET Q q 0 0 0 rg BT 64.34 119.10 Td (innovators’) Tj ET Q q 0 0 0 rg BT 109.15 119.10 Td ( ) Tj ET Q q 0 0 0 rg BT 111.37 119.10 Td (market ) Tj ET Q q 0 0 0 rg BT 141.36 119.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 184.59 119.10 Td (. ) Tj ET Q q 0 0 0 rg BT 189.32 119.10 Td (First, ) Tj ET Q q 0 0 0 rg BT 212.39 119.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 244.04 119.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 289.02 119.10 Td (have ) Tj ET Q q 0 0 0 rg BT 310.13 119.10 Td (increasingly ) Tj ET Q q 0 0 0 rg BT 361.22 119.10 Td (sought ) Tj ET Q q 0 0 0 rg BT 390.12 119.10 Td (to ) Tj ET Q q 0 0 0 rg BT 400.12 119.10 Td (challenge ) Tj ET Q q 0 0 0 rg BT 440.66 119.10 Td (innovators’) Tj ET Q q 0 0 0 rg BT 485.46 119.10 Td ( ) Tj ET Q q 0 0 0 rg BT 487.69 119.10 Td (basic ) Tj ET Q q 0 0 0 rg BT 510.46 119.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 541.01 119.10 Td (covering ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 107.10 Td (major ) Tj ET Q q 0 0 0 rg BT 62.63 107.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 127.02 107.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 167.27 107.10 Td (Second, ) Tj ET Q q 0 0 0 rg BT 202.51 107.10 Td (statutory ) Tj ET Q q 0 0 0 rg BT 240.82 107.10 Td (and ) Tj ET Q q 0 0 0 rg BT 258.57 107.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 302.97 107.10 Td (provisions ) Tj ET Q q 0 0 0 rg BT 347.95 107.10 Td (in ) Tj ET Q q 0 0 0 rg BT 359.04 107.10 Td (the ) Tj ET Q q 0 0 0 rg BT 374.56 107.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 395.66 107.10 Td (limit ) Tj ET Q q 0 0 0 rg BT 417.86 107.10 Td (the ) Tj ET Q q 0 0 0 rg BT 433.38 107.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 462.25 107.10 Td (of ) Tj ET Q q 0 0 0 rg BT 473.89 107.10 Td (an ) Tj ET Q q 0 0 0 rg BT 486.63 107.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 528.27 107.10 Td (company ) Tj ET Q q 0 0 0 rg BT 568.23 107.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 95.10 Td (prevent ) Tj ET Q q 0 0 0 rg BT 69.08 95.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 101.60 95.10 Td (and ) Tj ET Q q 0 0 0 rg BT 119.13 95.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 162.78 95.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 188.09 95.10 Td (from ) Tj ET Q q 0 0 0 rg BT 210.63 95.10 Td (being ) Tj ET Q q 0 0 0 rg BT 235.94 95.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 276.24 95.10 Td (and ) Tj ET Q q 0 0 0 rg BT 293.77 95.10 Td (launched ) Tj ET Q q 0 0 0 rg BT 332.96 95.10 Td (while ) Tj ET Q q 0 0 0 rg BT 358.27 95.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 385.80 95.10 Td (litigation ) Tj ET Q q 0 0 0 rg BT 425.01 95.10 Td (is ) Tj ET Q q 0 0 0 rg BT 434.77 95.10 Td (ongoing. ) Tj ET Q q 0 0 0 rg BT 472.46 95.10 Td (As ) Tj ET Q q 0 0 0 rg BT 486.67 95.10 Td (a ) Tj ET Q q 0 0 0 rg BT 494.20 95.10 Td (result ) Tj ET Q q 0 0 0 rg BT 519.51 95.10 Td (of ) Tj ET Q q 0 0 0 rg BT 530.94 95.10 Td (all ) Tj ET Q q 0 0 0 rg BT 544.03 95.10 Td (of ) Tj ET Q q 0 0 0 rg BT 555.45 95.10 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 83.10 Td (developments, ) Tj ET Q q 0 0 0 rg BT 97.13 83.10 Td (it ) Tj ET Q q 0 0 0 rg BT 105.78 83.10 Td (is ) Tj ET Q q 0 0 0 rg BT 115.53 83.10 Td (not ) Tj ET Q q 0 0 0 rg BT 131.40 83.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 167.27 83.10 Td (to ) Tj ET Q q 0 0 0 rg BT 178.13 83.10 Td (predict ) Tj ET Q q 0 0 0 rg BT 208.99 83.10 Td (the ) Tj ET Q q 0 0 0 rg BT 224.29 83.10 Td (length ) Tj ET Q q 0 0 0 rg BT 252.37 83.10 Td (of ) Tj ET Q q 0 0 0 rg BT 263.79 83.10 Td (market ) Tj ET Q q 0 0 0 rg BT 294.65 83.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 341.62 83.10 Td (for ) Tj ET Q q 0 0 0 rg BT 356.36 83.10 Td (a ) Tj ET Q q 0 0 0 rg BT 363.89 83.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 405.29 83.10 Td (product ) Tj ET Q q 0 0 0 rg BT 438.92 83.10 Td (with ) Tj ET Q q 0 0 0 rg BT 459.79 83.10 Td (certainty ) Tj ET Q q 0 0 0 rg BT 497.86 83.10 Td (based ) Tj ET Q q 0 0 0 rg BT 523.72 83.10 Td (solely ) Tj ET Q q 0 0 0 rg BT 550.69 83.10 Td (on ) Tj ET Q q 0 0 0 rg BT 563.78 83.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 71.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 79.04 71.10 Td (of ) Tj ET Q q 0 0 0 rg BT 89.87 71.10 Td (the ) Tj ET Q q 0 0 0 rg BT 104.59 71.10 Td (relevant ) Tj ET Q q 0 0 0 rg BT 139.29 71.10 Td (patent\(s\) ) Tj ET Q q 0 0 0 rg BT 176.78 71.10 Td (or ) Tj ET Q q 0 0 0 rg BT 187.61 71.10 Td (the ) Tj ET Q q 0 0 0 rg BT 202.32 71.10 Td (current ) Tj ET Q q 0 0 0 rg BT 233.14 71.10 Td (forms ) Tj ET Q q 0 0 0 rg BT 258.97 71.10 Td (of ) Tj ET Q q 0 0 0 rg BT 269.80 71.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 313.39 71.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 356.63 71.10 Td (.) Tj ET Q endstream endobj 13 0 obj <> endobj 14 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (6) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (Eur) Tj ET Q q 0 0 0 rg BT 50.63 737.10 Td (opean Union) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 719.10 Td (Patents ) Tj ET Q q 0 0 0 rg BT 66.92 719.10 Td (on ) Tj ET Q q 0 0 0 rg BT 78.95 719.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 142.05 719.10 Td (products ) Tj ET Q q 0 0 0 rg BT 178.52 719.10 Td (are ) Tj ET Q q 0 0 0 rg BT 192.76 719.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 231.99 719.10 Td (enforceable ) Tj ET Q q 0 0 0 rg BT 280.65 719.10 Td (in ) Tj ET Q q 0 0 0 rg BT 290.46 719.10 Td (the ) Tj ET Q q 0 0 0 rg BT 304.71 719.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 320.07 719.10 Td (and, ) Tj ET Q q 0 0 0 rg BT 339.04 719.10 Td (as ) Tj ET Q q 0 0 0 rg BT 349.40 719.10 Td (in ) Tj ET Q q 0 0 0 rg BT 359.21 719.10 Td (the ) Tj ET Q q 0 0 0 rg BT 373.45 719.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 395.77 719.10 Td (may ) Tj ET Q q 0 0 0 rg BT 415.01 719.10 Td (be ) Tj ET Q q 0 0 0 rg BT 426.48 719.10 Td (extended ) Tj ET Q q 0 0 0 rg BT 464.61 719.10 Td (to ) Tj ET Q q 0 0 0 rg BT 474.41 719.10 Td (compensate ) Tj ET Q q 0 0 0 rg BT 523.65 719.10 Td (for ) Tj ET Q q 0 0 0 rg BT 537.34 719.10 Td (the ) Tj ET Q q 0 0 0 rg BT 551.58 719.10 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 707.10 Td (term ) Tj ET Q q 0 0 0 rg BT 56.83 707.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 73.77 707.10 Td (during ) Tj ET Q q 0 0 0 rg BT 102.38 707.10 Td (the ) Tj ET Q q 0 0 0 rg BT 117.10 707.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 160.69 707.10 Td (review ) Tj ET Q q 0 0 0 rg BT 190.40 707.10 Td (process. ) Tj ET Q q 0 0 0 rg BT 225.39 707.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 247.89 707.10 Td (extensions ) Tj ET Q q 0 0 0 rg BT 292.61 707.10 Td (are ) Tj ET Q q 0 0 0 rg BT 307.31 707.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 339.80 707.10 Td (on ) Tj ET Q q 0 0 0 rg BT 352.30 707.10 Td (a ) Tj ET Q q 0 0 0 rg BT 359.24 707.10 Td (country-by-country ) Tj ET Q q 0 0 0 rg BT 439.49 707.10 Td (basis.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 683.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.59 683.10 Td (primary ) Tj ET Q q 0 0 0 rg BT 87.29 683.10 Td (route ) Tj ET Q q 0 0 0 rg BT 109.88 683.10 Td (we ) Tj ET Q q 0 0 0 rg BT 123.58 683.10 Td (use ) Tj ET Q q 0 0 0 rg BT 138.96 683.10 Td (to ) Tj ET Q q 0 0 0 rg BT 148.78 683.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 175.82 683.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 218.40 683.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 273.20 683.10 Td (of ) Tj ET Q q 0 0 0 rg BT 283.58 683.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 346.70 683.10 Td (products ) Tj ET Q q 0 0 0 rg BT 383.18 683.10 Td (in ) Tj ET Q q 0 0 0 rg BT 393.00 683.10 Td (the ) Tj ET Q q 0 0 0 rg BT 407.26 683.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 422.63 683.10 Td (is ) Tj ET Q q 0 0 0 rg BT 431.35 683.10 Td (through ) Tj ET Q q 0 0 0 rg BT 464.50 683.10 Td (the ) Tj ET Q q 0 0 0 rg BT 478.76 683.10 Td (“centralized ) Tj ET Q q 0 0 0 rg BT 529.10 683.10 Td (procedure.” ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 671.10 Td (This ) Tj ET Q q 0 0 0 rg BT 57.40 671.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 101.00 671.10 Td (is ) Tj ET Q q 0 0 0 rg BT 111.29 671.10 Td (compulsory ) Tj ET Q q 0 0 0 rg BT 162.13 671.10 Td (for ) Tj ET Q q 0 0 0 rg BT 177.41 671.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 208.24 671.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 272.93 671.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 313.49 671.10 Td (in ) Tj ET Q q 0 0 0 rg BT 324.89 671.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 366.83 671.10 Td (those ) Tj ET Q q 0 0 0 rg BT 391.56 671.10 Td (using ) Tj ET Q q 0 0 0 rg BT 416.85 671.10 Td (biotechnological ) Tj ET Q q 0 0 0 rg BT 487.12 671.10 Td (processes, ) Tj ET Q q 0 0 0 rg BT 531.56 671.10 Td (and ) Tj ET Q q 0 0 0 rg BT 549.62 671.10 Td (is ) Tj ET Q q 0 0 0 rg BT 559.91 671.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 659.10 Td (available ) Tj ET Q q 0 0 0 rg BT 73.94 659.10 Td (for ) Tj ET Q q 0 0 0 rg BT 87.45 659.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 116.50 659.10 Td (new ) Tj ET Q q 0 0 0 rg BT 135.01 659.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 172.95 659.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 220.91 659.10 Td (and ) Tj ET Q q 0 0 0 rg BT 237.19 659.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 275.57 659.10 Td (A) Tj ET Q q 0 0 0 rg BT 282.24 659.10 Td ( ) Tj ET Q q 0 0 0 rg BT 284.09 659.10 Td (company ) Tj ET Q q 0 0 0 rg BT 322.60 659.10 Td (seeking ) Tj ET Q q 0 0 0 rg BT 355.00 659.10 Td (to ) Tj ET Q q 0 0 0 rg BT 364.62 659.10 Td (market ) Tj ET Q q 0 0 0 rg BT 394.24 659.10 Td (an ) Tj ET Q q 0 0 0 rg BT 405.52 659.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 449.59 659.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 512.51 659.10 Td (product ) Tj ET Q q 0 0 0 rg BT 544.91 659.10 Td (through ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 647.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.28 647.10 Td (centralized ) Tj ET Q q 0 0 0 rg BT 98.21 647.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 141.25 647.10 Td (must ) Tj ET Q q 0 0 0 rg BT 163.76 647.10 Td (file ) Tj ET Q q 0 0 0 rg BT 180.15 647.10 Td (a ) Tj ET Q q 0 0 0 rg BT 187.65 647.10 Td (complete ) Tj ET Q q 0 0 0 rg BT 227.37 647.10 Td (set ) Tj ET Q q 0 0 0 rg BT 241.54 647.10 Td (of ) Tj ET Q q 0 0 0 rg BT 252.94 647.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 279.88 647.10 Td (data ) Tj ET Q q 0 0 0 rg BT 299.60 647.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.11 647.10 Td (ef) Tj ET Q q 0 0 0 rg BT 324.69 647.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 352.18 647.10 Td (data ) Tj ET Q q 0 0 0 rg BT 371.90 647.10 Td (as ) Tj ET Q q 0 0 0 rg BT 383.30 647.10 Td (part ) Tj ET Q q 0 0 0 rg BT 401.91 647.10 Td (of ) Tj ET Q q 0 0 0 rg BT 413.31 647.10 Td (an ) Tj ET Q q 0 0 0 rg BT 425.81 647.10 Td (MAA) Tj ET Q q 0 0 0 rg BT 448.59 647.10 Td ( ) Tj ET Q q 0 0 0 rg BT 451.66 647.10 Td (with ) Tj ET Q q 0 0 0 rg BT 472.50 647.10 Td (the ) Tj ET Q q 0 0 0 rg BT 487.79 647.10 Td (EMA. ) Tj ET Q q 0 0 0 rg BT 514.90 647.10 Td (After ) Tj ET Q q 0 0 0 rg BT 539.06 647.10 Td (the ) Tj ET Q q 0 0 0 rg BT 554.34 647.10 Td (EMA) Tj ET Q q 0 0 0 rg BT 576.01 647.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 635.10 Td (evaluates ) Tj ET Q q 0 0 0 rg BT 75.94 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 90.89 635.10 Td (MAA, ) Tj ET Q q 0 0 0 rg BT 119.46 635.10 Td (it ) Tj ET Q q 0 0 0 rg BT 127.76 635.10 Td (provides ) Tj ET Q q 0 0 0 rg BT 164.93 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 172.11 635.10 Td (recommendation ) Tj ET Q q 0 0 0 rg BT 242.04 635.10 Td (to ) Tj ET Q q 0 0 0 rg BT 252.56 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 267.51 635.10 Td (EC ) Tj ET Q q 0 0 0 rg BT 283.03 635.10 Td (and ) Tj ET Q q 0 0 0 rg BT 300.20 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 315.16 635.10 Td (EC ) Tj ET Q q 0 0 0 rg BT 330.67 635.10 Td (then ) Tj ET Q q 0 0 0 rg BT 350.62 635.10 Td (approves ) Tj ET Q q 0 0 0 rg BT 389.46 635.10 Td (or ) Tj ET Q q 0 0 0 rg BT 400.53 635.10 Td (denies ) Tj ET Q q 0 0 0 rg BT 428.81 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 443.76 635.10 Td (MAA. ) Tj ET Q q 0 0 0 rg BT 472.34 635.10 Td (It ) Tj ET Q q 0 0 0 rg BT 481.18 635.10 Td (is ) Tj ET Q q 0 0 0 rg BT 490.59 635.10 Td (also ) Tj ET Q q 0 0 0 rg BT 509.43 635.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 544.95 635.10 Td (for ) Tj ET Q q 0 0 0 rg BT 559.34 635.10 Td (new ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 623.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 73.96 623.10 Td (products ) Tj ET Q q 0 0 0 rg BT 110.26 623.10 Td (to ) Tj ET Q q 0 0 0 rg BT 119.91 623.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 146.77 623.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 189.18 623.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 243.80 623.10 Td (in ) Tj ET Q q 0 0 0 rg BT 253.45 623.10 Td (the ) Tj ET Q q 0 0 0 rg BT 267.53 623.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 282.73 623.10 Td (through ) Tj ET Q q 0 0 0 rg BT 315.70 623.10 Td (a ) Tj ET Q q 0 0 0 rg BT 322.01 623.10 Td (“mutual ) Tj ET Q q 0 0 0 rg BT 356.09 623.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 403.49 623.10 Td (procedure,” ) Tj ET Q q 0 0 0 rg BT 452.28 623.10 Td (in ) Tj ET Q q 0 0 0 rg BT 461.92 623.10 Td (which ) Tj ET Q q 0 0 0 rg BT 488.23 623.10 Td (an ) Tj ET Q q 0 0 0 rg BT 499.53 623.10 Td (application ) Tj ET Q q 0 0 0 rg BT 545.83 623.10 Td (is ) Tj ET Q q 0 0 0 rg BT 554.36 623.10 Td (made ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 611.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.71 611.10 Td (a ) Tj ET Q q 0 0 0 rg BT 54.07 611.10 Td (single ) Tj ET Q q 0 0 0 rg BT 80.89 611.10 Td (member ) Tj ET Q q 0 0 0 rg BT 116.58 611.10 Td (state, ) Tj ET Q q 0 0 0 rg BT 140.33 611.10 Td (and ) Tj ET Q q 0 0 0 rg BT 157.69 611.10 Td (if ) Tj ET Q q 0 0 0 rg BT 166.73 611.10 Td (the ) Tj ET Q q 0 0 0 rg BT 181.87 611.10 Td (member ) Tj ET Q q 0 0 0 rg BT 217.56 611.10 Td (state ) Tj ET Q q 0 0 0 rg BT 238.82 611.10 Td (approves ) Tj ET Q q 0 0 0 rg BT 277.84 611.10 Td (the ) Tj ET Q q 0 0 0 rg BT 292.99 611.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 356.99 611.10 Td (product ) Tj ET Q q 0 0 0 rg BT 390.46 611.10 Td (under ) Tj ET Q q 0 0 0 rg BT 416.16 611.10 Td (a ) Tj ET Q q 0 0 0 rg BT 423.52 611.10 Td (national ) Tj ET Q q 0 0 0 rg BT 458.66 611.10 Td (procedure, ) Tj ET Q q 0 0 0 rg BT 504.07 611.10 Td (then ) Tj ET Q q 0 0 0 rg BT 524.21 611.10 Td (the ) Tj ET Q q 0 0 0 rg BT 539.35 611.10 Td (applicant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 599.10 Td (may ) Tj ET Q q 0 0 0 rg BT 55.72 599.10 Td (submit ) Tj ET Q q 0 0 0 rg BT 85.44 599.10 Td (that ) Tj ET Q q 0 0 0 rg BT 102.94 599.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 140.42 599.10 Td (to ) Tj ET Q q 0 0 0 rg BT 150.70 599.10 Td (the ) Tj ET Q q 0 0 0 rg BT 165.42 599.10 Td (mutual ) Tj ET Q q 0 0 0 rg BT 195.69 599.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 243.73 599.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 286.21 599.10 Td (of ) Tj ET Q q 0 0 0 rg BT 297.04 599.10 Td (some ) Tj ET Q q 0 0 0 rg BT 320.65 599.10 Td (or ) Tj ET Q q 0 0 0 rg BT 331.48 599.10 Td (all ) Tj ET Q q 0 0 0 rg BT 343.97 599.10 Td (other ) Tj ET Q q 0 0 0 rg BT 367.02 599.10 Td (member ) Tj ET Q q 0 0 0 rg BT 402.28 599.10 Td (states.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 575.10 Td (After ) Tj ET Q q 0 0 0 rg BT 60.04 575.10 Td (obtaining ) Tj ET Q q 0 0 0 rg BT 100.75 575.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 144.23 575.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 199.93 575.10 Td (approval, ) Tj ET Q q 0 0 0 rg BT 240.35 575.10 Td (a ) Tj ET Q q 0 0 0 rg BT 247.73 575.10 Td (company ) Tj ET Q q 0 0 0 rg BT 287.32 575.10 Td (must ) Tj ET Q q 0 0 0 rg BT 309.71 575.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 337.64 575.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 368.91 575.10 Td (and ) Tj ET Q q 0 0 0 rg BT 386.28 575.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 449.20 575.10 Td (for ) Tj ET Q q 0 0 0 rg BT 463.80 575.10 Td (the ) Tj ET Q q 0 0 0 rg BT 478.96 575.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 542.97 575.10 Td (product, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 563.10 Td (which ) Tj ET Q q 0 0 0 rg BT 63.02 563.10 Td (is ) Tj ET Q q 0 0 0 rg BT 72.26 563.10 Td (typically ) Tj ET Q q 0 0 0 rg BT 109.83 563.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 140.74 563.10 Td (to ) Tj ET Q q 0 0 0 rg BT 151.09 563.10 Td (member ) Tj ET Q q 0 0 0 rg BT 186.43 563.10 Td (state ) Tj ET Q q 0 0 0 rg BT 207.34 563.10 Td (law) Tj ET Q q 0 0 0 rg BT 221.13 563.10 Td (. ) Tj ET Q q 0 0 0 rg BT 226.21 563.10 Td (In ) Tj ET Q q 0 0 0 rg BT 237.11 563.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 266.89 563.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 282.80 563.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 324.54 563.10 Td (this ) Tj ET Q q 0 0 0 rg BT 341.56 563.10 Td (process ) Tj ET Q q 0 0 0 rg BT 374.13 563.10 Td (can ) Tj ET Q q 0 0 0 rg BT 390.58 563.10 Td (take ) Tj ET Q q 0 0 0 rg BT 409.82 563.10 Td (place ) Tj ET Q q 0 0 0 rg BT 433.49 563.10 Td (simultaneously ) Tj ET Q q 0 0 0 rg BT 496.62 563.10 Td (while ) Tj ET Q q 0 0 0 rg BT 521.42 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 536.21 563.10 Td (product ) Tj ET Q q 0 0 0 rg BT 569.33 563.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 551.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 75.97 551.10 Td (but ) Tj ET Q q 0 0 0 rg BT 91.52 551.10 Td (in ) Tj ET Q q 0 0 0 rg BT 102.07 551.10 Td (other ) Tj ET Q q 0 0 0 rg BT 125.39 551.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 141.49 551.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 183.41 551.10 Td (this ) Tj ET Q q 0 0 0 rg BT 200.63 551.10 Td (process ) Tj ET Q q 0 0 0 rg BT 233.39 551.10 Td (must ) Tj ET Q q 0 0 0 rg BT 255.61 551.10 Td (be ) Tj ET Q q 0 0 0 rg BT 267.82 551.10 Td (completed ) Tj ET Q q 0 0 0 rg BT 312.24 551.10 Td (before ) Tj ET Q q 0 0 0 rg BT 340.54 551.10 Td (the ) Tj ET Q q 0 0 0 rg BT 355.53 551.10 Td (company ) Tj ET Q q 0 0 0 rg BT 394.96 551.10 Td (can ) Tj ET Q q 0 0 0 rg BT 411.60 551.10 Td (market ) Tj ET Q q 0 0 0 rg BT 442.14 551.10 Td (the ) Tj ET Q q 0 0 0 rg BT 457.12 551.10 Td (new ) Tj ET Q q 0 0 0 rg BT 476.55 551.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 512.17 551.10 Td (The ) Tj ET Q q 0 0 0 rg BT 530.49 551.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 561.58 551.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 539.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 98.48 539.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 140.96 539.10 Td (can ) Tj ET Q q 0 0 0 rg BT 157.33 539.10 Td (take ) Tj ET Q q 0 0 0 rg BT 176.49 539.10 Td (months ) Tj ET Q q 0 0 0 rg BT 208.44 539.10 Td (and ) Tj ET Q q 0 0 0 rg BT 225.38 539.10 Td (sometimes ) Tj ET Q q 0 0 0 rg BT 270.65 539.10 Td (years ) Tj ET Q q 0 0 0 rg BT 294.25 539.10 Td (to ) Tj ET Q q 0 0 0 rg BT 304.53 539.10 Td (complete.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 515.10 Td (Throughout ) Tj ET Q q 0 0 0 rg BT 86.42 515.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.84 515.10 Td (EU, ) Tj ET Q q 0 0 0 rg BT 120.88 515.10 Td (all ) Tj ET Q q 0 0 0 rg BT 134.08 515.10 Td (products ) Tj ET Q q 0 0 0 rg BT 171.72 515.10 Td (for ) Tj ET Q q 0 0 0 rg BT 186.58 515.10 Td (which ) Tj ET Q q 0 0 0 rg BT 214.23 515.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 257.97 515.10 Td (authorizations ) Tj ET Q q 0 0 0 rg BT 317.83 515.10 Td (have ) Tj ET Q q 0 0 0 rg BT 339.91 515.10 Td (been ) Tj ET Q q 0 0 0 rg BT 361.99 515.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 383.52 515.10 Td (after ) Tj ET Q q 0 0 0 rg BT 405.04 515.10 Td (October/November ) Tj ET Q q 0 0 0 rg BT 485.44 515.10 Td (2005 ) Tj ET Q q 0 0 0 rg BT 508.64 515.10 Td (are ) Tj ET Q q 0 0 0 rg BT 524.06 515.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 555.59 515.10 Td (to ) Tj ET Q q 0 0 0 rg BT 566.57 515.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 503.10 Td (“8+2+1” ) Tj ET Q q 0 0 0 rg BT 72.88 503.10 Td (regime. ) Tj ET Q q 0 0 0 rg BT 104.88 503.10 Td (Eight ) Tj ET Q q 0 0 0 rg BT 128.27 503.10 Td (years ) Tj ET Q q 0 0 0 rg BT 151.09 503.10 Td (after ) Tj ET Q q 0 0 0 rg BT 171.14 503.10 Td (the ) Tj ET Q q 0 0 0 rg BT 185.08 503.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 225.13 503.10 Td (has ) Tj ET Q q 0 0 0 rg BT 240.19 503.10 Td (received ) Tj ET Q q 0 0 0 rg BT 275.78 503.10 Td (its ) Tj ET Q q 0 0 0 rg BT 286.96 503.10 Td (first ) Tj ET Q q 0 0 0 rg BT 304.79 503.10 Td (community ) Tj ET Q q 0 0 0 rg BT 352.07 503.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 406.56 503.10 Td (for ) Tj ET Q q 0 0 0 rg BT 419.95 503.10 Td (a ) Tj ET Q q 0 0 0 rg BT 426.11 503.10 Td (medicinal ) Tj ET Q q 0 0 0 rg BT 467.27 503.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 502.04 503.10 Td (a ) Tj ET Q q 0 0 0 rg BT 508.21 503.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 539.36 503.10 Td (company ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 491.10 Td (may ) Tj ET Q q 0 0 0 rg BT 55.87 491.10 Td (file ) Tj ET Q q 0 0 0 rg BT 71.84 491.10 Td (a ) Tj ET Q q 0 0 0 rg BT 78.93 491.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 122.12 491.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 177.53 491.10 Td (application ) Tj ET Q q 0 0 0 rg BT 224.60 491.10 Td (for ) Tj ET Q q 0 0 0 rg BT 238.91 491.10 Td (that ) Tj ET Q q 0 0 0 rg BT 256.56 491.10 Td (product ) Tj ET Q q 0 0 0 rg BT 289.75 491.10 Td (with ) Tj ET Q q 0 0 0 rg BT 310.18 491.10 Td (the ) Tj ET Q q 0 0 0 rg BT 325.05 491.10 Td (health ) Tj ET Q q 0 0 0 rg BT 352.13 491.10 Td (authorities. ) Tj ET Q q 0 0 0 rg BT 399.49 491.10 Td (If ) Tj ET Q q 0 0 0 rg BT 408.80 491.10 Td (the ) Tj ET Q q 0 0 0 rg BT 423.66 491.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 466.85 491.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 522.26 491.10 Td (application ) Tj ET Q q 0 0 0 rg BT 569.34 491.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 479.10 Td (approved, ) Tj ET Q q 0 0 0 rg BT 77.49 479.10 Td (the ) Tj ET Q q 0 0 0 rg BT 91.50 479.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 122.71 479.10 Td (company ) Tj ET Q q 0 0 0 rg BT 161.15 479.10 Td (may ) Tj ET Q q 0 0 0 rg BT 180.16 479.10 Td (not ) Tj ET Q q 0 0 0 rg BT 194.72 479.10 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 255.36 479.10 Td (the ) Tj ET Q q 0 0 0 rg BT 269.36 479.10 Td (product ) Tj ET Q q 0 0 0 rg BT 301.70 479.10 Td (until ) Tj ET Q q 0 0 0 rg BT 321.82 479.10 Td (after ) Tj ET Q q 0 0 0 rg BT 341.92 479.10 Td (either ) Tj ET Q q 0 0 0 rg BT 366.47 479.10 Td (10 ) Tj ET Q q 0 0 0 rg BT 378.26 479.10 Td (or ) Tj ET Q q 0 0 0 rg BT 388.38 479.10 Td (1) Tj ET Q q 0 0 0 rg BT 393.01 479.10 Td (1 ) Tj ET Q q 0 0 0 rg BT 399.79 479.10 Td (years ) Tj ET Q q 0 0 0 rg BT 422.68 479.10 Td (have ) Tj ET Q q 0 0 0 rg BT 443.34 479.10 Td (elapsed ) Tj ET Q q 0 0 0 rg BT 475.12 479.10 Td (from ) Tj ET Q q 0 0 0 rg BT 496.34 479.10 Td (the ) Tj ET Q q 0 0 0 rg BT 510.35 479.10 Td (initial ) Tj ET Q q 0 0 0 rg BT 535.46 479.10 Td (marketing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 467.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 91.23 467.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 123.69 467.10 Td (to ) Tj ET Q q 0 0 0 rg BT 133.95 467.10 Td (the ) Tj ET Q q 0 0 0 rg BT 148.64 467.10 Td (innovator) Tj ET Q q 0 0 0 rg BT 186.41 467.10 Td (. ) Tj ET Q q 0 0 0 rg BT 191.21 467.10 Td (The ) Tj ET Q q 0 0 0 rg BT 209.23 467.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 244.48 467.10 Td (extension ) Tj ET Q q 0 0 0 rg BT 285.28 467.10 Td (to ) Tj ET Q q 0 0 0 rg BT 295.53 467.10 Td (1) Tj ET Q q 0 0 0 rg BT 300.16 467.10 Td (1 ) Tj ET Q q 0 0 0 rg BT 307.64 467.10 Td (years ) Tj ET Q q 0 0 0 rg BT 331.21 467.10 Td (is ) Tj ET Q q 0 0 0 rg BT 340.35 467.10 Td (available ) Tj ET Q q 0 0 0 rg BT 378.92 467.10 Td (if ) Tj ET Q q 0 0 0 rg BT 387.50 467.10 Td (the ) Tj ET Q q 0 0 0 rg BT 402.19 467.10 Td (innovator) Tj ET Q q 0 0 0 rg BT 440.12 467.10 Td (, ) Tj ET Q q 0 0 0 rg BT 445.09 467.10 Td (during ) Tj ET Q q 0 0 0 rg BT 473.68 467.10 Td (the ) Tj ET Q q 0 0 0 rg BT 488.37 467.10 Td (first ) Tj ET Q q 0 0 0 rg BT 506.95 467.10 Td (eight ) Tj ET Q q 0 0 0 rg BT 529.42 467.10 Td (years ) Tj ET Q q 0 0 0 rg BT 552.99 467.10 Td (of ) Tj ET Q q 0 0 0 rg BT 563.80 467.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 455.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 78.58 455.10 Td (authorization, ) Tj ET Q q 0 0 0 rg BT 135.87 455.10 Td (obtains ) Tj ET Q q 0 0 0 rg BT 166.79 455.10 Td (an ) Tj ET Q q 0 0 0 rg BT 178.26 455.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 220.28 455.10 Td (indication ) Tj ET Q q 0 0 0 rg BT 262.31 455.10 Td (that ) Tj ET Q q 0 0 0 rg BT 279.34 455.10 Td (is ) Tj ET Q q 0 0 0 rg BT 288.04 455.10 Td (of ) Tj ET Q q 0 0 0 rg BT 298.40 455.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 342.65 455.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 374.11 455.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 403.91 455.10 Td (in ) Tj ET Q q 0 0 0 rg BT 413.72 455.10 Td (comparison ) Tj ET Q q 0 0 0 rg BT 462.41 455.10 Td (with ) Tj ET Q q 0 0 0 rg BT 482.22 455.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 515.92 455.10 Td (treatments. ) Tj ET Q q 0 0 0 rg BT 562.11 455.10 Td (For ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 443.10 Td (products ) Tj ET Q q 0 0 0 rg BT 73.10 443.10 Td (that ) Tj ET Q q 0 0 0 rg BT 90.75 443.10 Td (were ) Tj ET Q q 0 0 0 rg BT 112.84 443.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 133.82 443.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 155.91 443.10 Td (to ) Tj ET Q q 0 0 0 rg BT 166.35 443.10 Td (October/November ) Tj ET Q q 0 0 0 rg BT 246.20 443.10 Td (2005, ) Tj ET Q q 0 0 0 rg BT 271.36 443.10 Td (there ) Tj ET Q q 0 0 0 rg BT 294.00 443.10 Td (is ) Tj ET Q q 0 0 0 rg BT 303.33 443.10 Td (a ) Tj ET Q q 0 0 0 rg BT 310.43 443.10 Td (10-year ) Tj ET Q q 0 0 0 rg BT 343.62 443.10 Td (period ) Tj ET Q q 0 0 0 rg BT 371.82 443.10 Td (of ) Tj ET Q q 0 0 0 rg BT 382.81 443.10 Td (data ) Tj ET Q q 0 0 0 rg BT 402.13 443.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 445.33 443.10 Td (under ) Tj ET Q q 0 0 0 rg BT 470.75 443.10 Td (the ) Tj ET Q q 0 0 0 rg BT 485.63 443.10 Td (centralized ) Tj ET Q q 0 0 0 rg BT 532.14 443.10 Td (procedures ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 431.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 431.10 Td (a ) Tj ET Q q 0 0 0 rg BT 59.88 431.10 Td (period ) Tj ET Q q 0 0 0 rg BT 87.92 431.10 Td (of ) Tj ET Q q 0 0 0 rg BT 98.75 431.10 Td (either ) Tj ET Q q 0 0 0 rg BT 124.02 431.10 Td (six ) Tj ET Q q 0 0 0 rg BT 138.19 431.10 Td (or ) Tj ET Q q 0 0 0 rg BT 149.02 431.10 Td (10 ) Tj ET Q q 0 0 0 rg BT 161.52 431.10 Td (years ) Tj ET Q q 0 0 0 rg BT 185.12 431.10 Td (under ) Tj ET Q q 0 0 0 rg BT 210.38 431.10 Td (the ) Tj ET Q q 0 0 0 rg BT 225.10 431.10 Td (mutual ) Tj ET Q q 0 0 0 rg BT 255.38 431.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 303.42 431.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 345.89 431.10 Td (\(depending ) Tj ET Q q 0 0 0 rg BT 393.38 431.10 Td (on ) Tj ET Q q 0 0 0 rg BT 405.88 431.10 Td (the ) Tj ET Q q 0 0 0 rg BT 420.59 431.10 Td (member ) Tj ET Q q 0 0 0 rg BT 455.86 431.10 Td (state\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 407.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.98 407.10 Td (contrast ) Tj ET Q q 0 0 0 rg BT 81.29 407.10 Td (to ) Tj ET Q q 0 0 0 rg BT 91.73 407.10 Td (the ) Tj ET Q q 0 0 0 rg BT 106.60 407.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 129.53 407.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 160.51 407.10 Td (in ) Tj ET Q q 0 0 0 rg BT 170.94 407.10 Td (the ) Tj ET Q q 0 0 0 rg BT 185.81 407.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 201.80 407.10 Td (are ) Tj ET Q q 0 0 0 rg BT 216.66 407.10 Td (not ) Tj ET Q q 0 0 0 rg BT 232.09 407.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 256.41 407.10 Td (with ) Tj ET Q q 0 0 0 rg BT 276.84 407.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 320.59 407.10 Td (authorities. ) Tj ET Q q 0 0 0 rg BT 367.96 407.10 Td (Generic ) Tj ET Q q 0 0 0 rg BT 402.25 407.10 Td (versions ) Tj ET Q q 0 0 0 rg BT 438.24 407.10 Td (of ) Tj ET Q q 0 0 0 rg BT 449.22 407.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 512.95 407.10 Td (products ) Tj ET Q q 0 0 0 rg BT 550.04 407.10 Td (can ) Tj ET Q q 0 0 0 rg BT 566.57 407.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 395.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 76.07 395.10 Td (after ) Tj ET Q q 0 0 0 rg BT 97.25 395.10 Td (data ) Tj ET Q q 0 0 0 rg BT 116.77 395.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 160.18 395.10 Td (expires, ) Tj ET Q q 0 0 0 rg BT 194.42 395.10 Td (regardless ) Tj ET Q q 0 0 0 rg BT 237.83 395.10 Td (of ) Tj ET Q q 0 0 0 rg BT 249.02 395.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 284.09 395.10 Td (the ) Tj ET Q q 0 0 0 rg BT 299.17 395.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 340.37 395.10 Td (holds ) Tj ET Q q 0 0 0 rg BT 364.90 395.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 396.09 395.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 433.94 395.10 Td (its ) Tj ET Q q 0 0 0 rg BT 446.25 395.10 Td (drug. ) Tj ET Q q 0 0 0 rg BT 469.74 395.10 Td (Thus, ) Tj ET Q q 0 0 0 rg BT 495.11 395.10 Td (it ) Tj ET Q q 0 0 0 rg BT 503.53 395.10 Td (is ) Tj ET Q q 0 0 0 rg BT 513.06 395.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 548.71 395.10 Td (that ) Tj ET Q q 0 0 0 rg BT 566.57 395.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 383.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 77.23 383.10 Td (may ) Tj ET Q q 0 0 0 rg BT 97.35 383.10 Td (be ) Tj ET Q q 0 0 0 rg BT 109.69 383.10 Td (seeking ) Tj ET Q q 0 0 0 rg BT 143.13 383.10 Td (to ) Tj ET Q q 0 0 0 rg BT 153.81 383.10 Td (enforce ) Tj ET Q q 0 0 0 rg BT 186.69 383.10 Td (its ) Tj ET Q q 0 0 0 rg BT 199.04 383.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 230.27 383.10 Td (against ) Tj ET Q q 0 0 0 rg BT 261.50 383.10 Td (a ) Tj ET Q q 0 0 0 rg BT 268.84 383.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 301.16 383.10 Td (competitor ) Tj ET Q q 0 0 0 rg BT 347.38 383.10 Td (that ) Tj ET Q q 0 0 0 rg BT 365.28 383.10 Td (is ) Tj ET Q q 0 0 0 rg BT 374.85 383.10 Td (already ) Tj ET Q q 0 0 0 rg BT 407.18 383.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 450.62 383.10 Td (its ) Tj ET Q q 0 0 0 rg BT 462.97 383.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 498.28 383.10 Td (Also, ) Tj ET Q q 0 0 0 rg BT 522.57 383.10 Td (the ) Tj ET Q q 0 0 0 rg BT 537.69 383.10 Td (European ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 371.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 63.71 371.10 Td (system ) Tj ET Q q 0 0 0 rg BT 94.77 371.10 Td (has ) Tj ET Q q 0 0 0 rg BT 111.38 371.10 Td (an ) Tj ET Q q 0 0 0 rg BT 124.09 371.10 Td (opposition ) Tj ET Q q 0 0 0 rg BT 169.60 371.10 Td (procedure ) Tj ET Q q 0 0 0 rg BT 212.85 371.10 Td (in ) Tj ET Q q 0 0 0 rg BT 223.91 371.10 Td (which ) Tj ET Q q 0 0 0 rg BT 251.62 371.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 284.32 371.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 344.79 371.10 Td (may ) Tj ET Q q 0 0 0 rg BT 365.29 371.10 Td (challenge ) Tj ET Q q 0 0 0 rg BT 406.88 371.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.37 371.10 Td (validity ) Tj ET Q q 0 0 0 rg BT 456.20 371.10 Td (of ) Tj ET Q q 0 0 0 rg BT 467.81 371.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 499.41 371.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 537.68 371.10 Td (innovator ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 359.10 Td (products ) Tj ET Q q 0 0 0 rg BT 72.94 359.10 Td (within ) Tj ET Q q 0 0 0 rg BT 101.00 359.10 Td (nine ) Tj ET Q q 0 0 0 rg BT 120.71 359.10 Td (months ) Tj ET Q q 0 0 0 rg BT 152.66 359.10 Td (of ) Tj ET Q q 0 0 0 rg BT 163.49 359.10 Td (grant.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 335.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.51 335.10 Td (general, ) Tj ET Q q 0 0 0 rg BT 80.62 335.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 96.14 335.10 Td (law ) Tj ET Q q 0 0 0 rg BT 112.76 335.10 Td (treats ) Tj ET Q q 0 0 0 rg BT 136.60 335.10 Td (chemically-synthesized ) Tj ET Q q 0 0 0 rg BT 232.63 335.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 257.04 335.10 Td (and ) Tj ET Q q 0 0 0 rg BT 273.66 335.10 Td (biologically-derived ) Tj ET Q q 0 0 0 rg BT 356.93 335.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 381.34 335.10 Td (the ) Tj ET Q q 0 0 0 rg BT 395.74 335.10 Td (same ) Tj ET Q q 0 0 0 rg BT 418.47 335.10 Td (with ) Tj ET Q q 0 0 0 rg BT 438.43 335.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 468.93 335.10 Td (to ) Tj ET Q q 0 0 0 rg BT 478.89 335.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 525.50 335.10 Td (property ) Tj ET Q q 0 0 0 rg BT 561.56 335.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 323.10 Td (data ) Tj ET Q q 0 0 0 rg BT 54.83 323.10 Td (protection. ) Tj ET Q q 0 0 0 rg BT 100.04 323.10 Td (In ) Tj ET Q q 0 0 0 rg BT 110.54 323.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 145.49 323.10 Td (to ) Tj ET Q q 0 0 0 rg BT 155.44 323.10 Td (the ) Tj ET Q q 0 0 0 rg BT 169.83 323.10 Td (relevant ) Tj ET Q q 0 0 0 rg BT 204.20 323.10 Td (legislation ) Tj ET Q q 0 0 0 rg BT 248.03 323.10 Td (and ) Tj ET Q q 0 0 0 rg BT 264.64 323.10 Td (annexes ) Tj ET Q q 0 0 0 rg BT 299.02 323.10 Td (related ) Tj ET Q q 0 0 0 rg BT 328.40 323.10 Td (to ) Tj ET Q q 0 0 0 rg BT 338.35 323.10 Td (biologic ) Tj ET Q q 0 0 0 rg BT 373.29 323.10 Td (medicinal ) Tj ET Q q 0 0 0 rg BT 414.89 323.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 454.00 323.10 Td (the ) Tj ET Q q 0 0 0 rg BT 468.39 323.10 Td (EMA) Tj ET Q q 0 0 0 rg BT 490.06 323.10 Td ( ) Tj ET Q q 0 0 0 rg BT 492.23 323.10 Td (has ) Tj ET Q q 0 0 0 rg BT 507.74 323.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 534.91 323.10 Td (guidelines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 311.10 Td (that ) Tj ET Q q 0 0 0 rg BT 54.11 311.10 Td (outline ) Tj ET Q q 0 0 0 rg BT 85.00 311.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.34 311.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 143.45 311.10 Td (information ) Tj ET Q q 0 0 0 rg BT 193.78 311.10 Td (to ) Tj ET Q q 0 0 0 rg BT 204.67 311.10 Td (be ) Tj ET Q q 0 0 0 rg BT 217.23 311.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 255.89 311.10 Td (for ) Tj ET Q q 0 0 0 rg BT 270.67 311.10 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 314.34 311.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 354.40 311.10 Td (also ) Tj ET Q q 0 0 0 rg BT 373.62 311.10 Td (known ) Tj ET Q q 0 0 0 rg BT 403.96 311.10 Td (as ) Tj ET Q q 0 0 0 rg BT 415.41 311.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 447.95 311.10 Td (biologics, ) Tj ET Q q 0 0 0 rg BT 490.23 311.10 Td (in ) Tj ET Q q 0 0 0 rg BT 501.13 311.10 Td (order ) Tj ET Q q 0 0 0 rg BT 525.35 311.10 Td (to ) Tj ET Q q 0 0 0 rg BT 536.24 311.10 Td (review ) Tj ET Q q 0 0 0 rg BT 566.57 311.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 299.10 Td (application ) Tj ET Q q 0 0 0 rg BT 82.93 299.10 Td (for ) Tj ET Q q 0 0 0 rg BT 97.09 299.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 140.13 299.10 Td (approval.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 275.10 Td (Japan) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.72 257.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 74.38 257.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 117.31 257.10 Td (of ) Tj ET Q q 0 0 0 rg BT 128.03 257.10 Td (new ) Tj ET Q q 0 0 0 rg BT 147.08 257.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 185.55 257.10 Td (entities ) Tj ET Q q 0 0 0 rg BT 216.83 257.10 Td (are ) Tj ET Q q 0 0 0 rg BT 231.42 257.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 271.01 257.10 Td (af) Tj ET Q q 0 0 0 rg BT 278.60 257.10 Td (forded ) Tj ET Q q 0 0 0 rg BT 307.09 257.10 Td (eight ) Tj ET Q q 0 0 0 rg BT 329.47 257.10 Td (years ) Tj ET Q q 0 0 0 rg BT 352.96 257.10 Td (of ) Tj ET Q q 0 0 0 rg BT 363.68 257.10 Td (data ) Tj ET Q q 0 0 0 rg BT 382.72 257.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 429.00 257.10 Td (for ) Tj ET Q q 0 0 0 rg BT 443.04 257.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 482.64 257.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 528.91 257.10 Td (and ) Tj ET Q q 0 0 0 rg BT 545.74 257.10 Td (dosage. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.10 Td (Patents ) Tj ET Q q 0 0 0 rg BT 68.04 245.10 Td (on ) Tj ET Q q 0 0 0 rg BT 81.20 245.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 145.44 245.10 Td (products ) Tj ET Q q 0 0 0 rg BT 183.03 245.10 Td (are ) Tj ET Q q 0 0 0 rg BT 198.40 245.10 Td (enforceable. ) Tj ET Q q 0 0 0 rg BT 250.69 245.10 Td (Generic ) Tj ET Q q 0 0 0 rg BT 285.49 245.10 Td (copies ) Tj ET Q q 0 0 0 rg BT 314.20 245.10 Td (can ) Tj ET Q q 0 0 0 rg BT 331.23 245.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 363.25 245.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 407.50 245.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 445.65 245.10 Td (after ) Tj ET Q q 0 0 0 rg BT 467.12 245.10 Td (data ) Tj ET Q q 0 0 0 rg BT 486.93 245.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 533.97 245.10 Td (and ) Tj ET Q q 0 0 0 rg BT 551.57 245.10 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (expirations. ) Tj ET Q q 0 0 0 rg BT 84.54 233.10 Td (As ) Tj ET Q q 0 0 0 rg BT 97.71 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 107.55 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 121.83 233.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 144.17 233.10 Td (patents ) Tj ET Q q 0 0 0 rg BT 174.56 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 184.40 233.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 209.23 233.10 Td (may ) Tj ET Q q 0 0 0 rg BT 228.50 233.10 Td (be ) Tj ET Q q 0 0 0 rg BT 240.00 233.10 Td (extended ) Tj ET Q q 0 0 0 rg BT 278.16 233.10 Td (to ) Tj ET Q q 0 0 0 rg BT 288.00 233.10 Td (compensate ) Tj ET Q q 0 0 0 rg BT 337.26 233.10 Td (for ) Tj ET Q q 0 0 0 rg BT 350.98 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 365.26 233.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 391.75 233.10 Td (term ) Tj ET Q q 0 0 0 rg BT 412.14 233.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 428.65 233.10 Td (during ) Tj ET Q q 0 0 0 rg BT 456.81 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 471.09 233.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 514.25 233.10 Td (review ) Tj ET Q q 0 0 0 rg BT 543.51 233.10 Td (process.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.65 209.10 Td (general, ) Tj ET Q q 0 0 0 rg BT 80.90 209.10 Td (Japanese ) Tj ET Q q 0 0 0 rg BT 118.76 209.10 Td (law ) Tj ET Q q 0 0 0 rg BT 135.52 209.10 Td (treats ) Tj ET Q q 0 0 0 rg BT 159.49 209.10 Td (chemically-synthesized ) Tj ET Q q 0 0 0 rg BT 255.67 209.10 Td (and ) Tj ET Q q 0 0 0 rg BT 272.43 209.10 Td (biologically-derived ) Tj ET Q q 0 0 0 rg BT 355.83 209.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 380.38 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 394.92 209.10 Td (same ) Tj ET Q q 0 0 0 rg BT 417.78 209.10 Td (with ) Tj ET Q q 0 0 0 rg BT 437.88 209.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 468.52 209.10 Td (to ) Tj ET Q q 0 0 0 rg BT 478.62 209.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 525.37 209.10 Td (property ) Tj ET Q q 0 0 0 rg BT 561.57 209.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (market ) Tj ET Q q 0 0 0 rg BT 66.26 197.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 109.50 197.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 173.10 Td (Rest of the W) Tj ET Q q 0 0 0 rg BT 88.12 173.10 Td (orld) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 155.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.33 155.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 84.98 155.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 115.87 155.10 Td (of ) Tj ET Q q 0 0 0 rg BT 126.20 155.10 Td (the ) Tj ET Q q 0 0 0 rg BT 140.41 155.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 162.69 155.10 Td (the ) Tj ET Q q 0 0 0 rg BT 176.91 155.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 192.24 155.10 Td (and ) Tj ET Q q 0 0 0 rg BT 208.67 155.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 235.94 155.10 Td (there ) Tj ET Q q 0 0 0 rg BT 257.93 155.10 Td (is ) Tj ET Q q 0 0 0 rg BT 266.59 155.10 Td (a ) Tj ET Q q 0 0 0 rg BT 273.03 155.10 Td (wide ) Tj ET Q q 0 0 0 rg BT 294.47 155.10 Td (variety ) Tj ET Q q 0 0 0 rg BT 324.23 155.10 Td (of ) Tj ET Q q 0 0 0 rg BT 334.56 155.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 355.99 155.10 Td (systems ) Tj ET Q q 0 0 0 rg BT 389.66 155.10 Td (with ) Tj ET Q q 0 0 0 rg BT 409.44 155.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 439.75 155.10 Td (to ) Tj ET Q q 0 0 0 rg BT 449.53 155.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 495.95 155.10 Td (property ) Tj ET Q q 0 0 0 rg BT 531.82 155.10 Td (and ) Tj ET Q q 0 0 0 rg BT 548.26 155.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 143.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 82.45 143.10 Td (of ) Tj ET Q q 0 0 0 rg BT 93.35 143.10 Td (pharmaceuticals. ) Tj ET Q q 0 0 0 rg BT 163.39 143.10 Td (Most ) Tj ET Q q 0 0 0 rg BT 186.52 143.10 Td (other ) Tj ET Q q 0 0 0 rg BT 209.64 143.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 253.30 143.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 292.52 143.10 Td (utilize ) Tj ET Q q 0 0 0 rg BT 320.08 143.10 Td (systems ) Tj ET Q q 0 0 0 rg BT 354.32 143.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 384.67 143.10 Td (to ) Tj ET Q q 0 0 0 rg BT 395.02 143.10 Td (either ) Tj ET Q q 0 0 0 rg BT 420.35 143.10 Td (the ) Tj ET Q q 0 0 0 rg BT 435.14 143.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 455.49 143.10 Td (or ) Tj ET Q q 0 0 0 rg BT 466.39 143.10 Td (the ) Tj ET Q q 0 0 0 rg BT 481.17 143.10 Td (EU. ) Tj ET Q q 0 0 0 rg BT 499.01 143.10 Td (Among ) Tj ET Q q 0 0 0 rg BT 531.58 143.10 Td (developing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 131.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 78.19 131.10 Td (some ) Tj ET Q q 0 0 0 rg BT 102.33 131.10 Td (have ) Tj ET Q q 0 0 0 rg BT 124.24 131.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 158.92 131.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 186.39 131.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 207.75 131.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 236.33 131.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 280.46 131.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 327.37 131.10 Td (laws, ) Tj ET Q q 0 0 0 rg BT 351.23 131.10 Td (while ) Tj ET Q q 0 0 0 rg BT 376.48 131.10 Td (others ) Tj ET Q q 0 0 0 rg BT 403.95 131.10 Td (have ) Tj ET Q q 0 0 0 rg BT 425.86 131.10 Td (not. ) Tj ET Q q 0 0 0 rg BT 444.17 131.10 Td (Some ) Tj ET Q q 0 0 0 rg BT 469.98 131.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 517.45 131.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 557.14 131.10 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 119.10 Td (formally ) Tj ET Q q 0 0 0 rg BT 73.22 119.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 107.67 119.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 128.78 119.10 Td (in ) Tj ET Q q 0 0 0 rg BT 139.35 119.10 Td (order ) Tj ET Q q 0 0 0 rg BT 163.24 119.10 Td (to ) Tj ET Q q 0 0 0 rg BT 173.80 119.10 Td (comply ) Tj ET Q q 0 0 0 rg BT 206.59 119.10 Td (with ) Tj ET Q q 0 0 0 rg BT 226.95 119.10 Td (WT) Tj ET Q q 0 0 0 rg BT 242.32 119.10 Td (O ) Tj ET Q q 0 0 0 rg BT 252.33 119.10 Td (commitments, ) Tj ET Q q 0 0 0 rg BT 312.05 119.10 Td (but ) Tj ET Q q 0 0 0 rg BT 327.62 119.10 Td (have ) Tj ET Q q 0 0 0 rg BT 349.28 119.10 Td (not ) Tj ET Q q 0 0 0 rg BT 364.85 119.10 Td (taken ) Tj ET Q q 0 0 0 rg BT 389.29 119.10 Td (steps ) Tj ET Q q 0 0 0 rg BT 412.08 119.10 Td (to ) Tj ET Q q 0 0 0 rg BT 422.65 119.10 Td (implement ) Tj ET Q q 0 0 0 rg BT 468.21 119.10 Td (these ) Tj ET Q q 0 0 0 rg BT 491.54 119.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 512.66 119.10 Td (in ) Tj ET Q q 0 0 0 rg BT 523.23 119.10 Td (a ) Tj ET Q q 0 0 0 rg BT 530.45 119.10 Td (meaningful ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 107.10 Td (way) Tj ET Q q 0 0 0 rg BT 52.01 107.10 Td (. ) Tj ET Q q 0 0 0 rg BT 56.88 107.10 Td (Enforcement ) Tj ET Q q 0 0 0 rg BT 110.88 107.10 Td (of ) Tj ET Q q 0 0 0 rg BT 121.40 107.10 Td (WT) Tj ET Q q 0 0 0 rg BT 136.77 107.10 Td (O ) Tj ET Q q 0 0 0 rg BT 146.36 107.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 177.05 107.10 Td (is ) Tj ET Q q 0 0 0 rg BT 186.08 107.10 Td (a ) Tj ET Q q 0 0 0 rg BT 192.89 107.10 Td (long ) Tj ET Q q 0 0 0 rg BT 213.03 107.10 Td (process ) Tj ET Q q 0 0 0 rg BT 245.38 107.10 Td (between ) Tj ET Q q 0 0 0 rg BT 281.06 107.10 Td (governments, ) Tj ET Q q 0 0 0 rg BT 337.58 107.10 Td (and ) Tj ET Q q 0 0 0 rg BT 354.39 107.10 Td (there ) Tj ET Q q 0 0 0 rg BT 376.74 107.10 Td (is ) Tj ET Q q 0 0 0 rg BT 385.77 107.10 Td (no ) Tj ET Q q 0 0 0 rg BT 398.14 107.10 Td (assurance ) Tj ET Q q 0 0 0 rg BT 439.37 107.10 Td (of ) Tj ET Q q 0 0 0 rg BT 450.06 107.10 Td (the ) Tj ET Q q 0 0 0 rg BT 464.64 107.10 Td (outcome. ) Tj ET Q q 0 0 0 rg BT 503.77 107.10 Td (Thus, ) Tj ET Q q 0 0 0 rg BT 528.64 107.10 Td (in ) Tj ET Q q 0 0 0 rg BT 538.78 107.10 Td (assessing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 95.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.35 95.10 Td (likely ) Tj ET Q q 0 0 0 rg BT 75.26 95.10 Td (future ) Tj ET Q q 0 0 0 rg BT 101.28 95.10 Td (market ) Tj ET Q q 0 0 0 rg BT 131.18 95.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 177.19 95.10 Td (of ) Tj ET Q q 0 0 0 rg BT 187.66 95.10 Td (our ) Tj ET Q q 0 0 0 rg BT 203.13 95.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 247.47 95.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 271.83 95.10 Td (in ) Tj ET Q q 0 0 0 rg BT 281.75 95.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 328.32 95.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 369.61 95.10 Td (we ) Tj ET Q q 0 0 0 rg BT 383.40 95.10 Td (take ) Tj ET Q q 0 0 0 rg BT 402.20 95.10 Td (into ) Tj ET Q q 0 0 0 rg BT 419.89 95.10 Td (account ) Tj ET Q q 0 0 0 rg BT 453.12 95.10 Td (not ) Tj ET Q q 0 0 0 rg BT 468.03 95.10 Td (only ) Tj ET Q q 0 0 0 rg BT 487.95 95.10 Td (formal ) Tj ET Q q 0 0 0 rg BT 516.74 95.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 538.31 95.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 563.22 95.10 Td (but ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 83.10 Td (political ) Tj ET Q q 0 0 0 rg BT 71.27 83.10 Td (and ) Tj ET Q q 0 0 0 rg BT 88.21 83.10 Td (other ) Tj ET Q q 0 0 0 rg BT 111.25 83.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 140.96 83.10 Td (as ) Tj ET Q q 0 0 0 rg BT 151.79 83.10 Td (well.) Tj ET Q endstream endobj 15 0 obj <> endobj 16 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.86 749.10 Td (following ) Tj ET Q q 0 0 0 rg BT 97.06 749.10 Td (chart ) Tj ET Q q 0 0 0 rg BT 120.36 749.10 Td (shows ) Tj ET Q q 0 0 0 rg BT 148.68 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 165.33 749.10 Td (key ) Tj ET Q q 0 0 0 rg BT 183.08 749.10 Td (products ) Tj ET Q q 0 0 0 rg BT 220.83 749.10 Td (together ) Tj ET Q q 0 0 0 rg BT 256.91 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 278.00 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 293.53 749.10 Td (year ) Tj ET Q q 0 0 0 rg BT 314.06 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 325.15 749.10 Td (which ) Tj ET Q q 0 0 0 rg BT 352.90 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 368.43 749.10 Td (earliest ) Tj ET Q q 0 0 0 rg BT 400.62 749.10 Td (basic ) Tj ET Q q 0 0 0 rg BT 424.48 749.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 471.68 749.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 490.55 749.10 Td (\(patent ) Tj ET Q q 0 0 0 rg BT 521.63 749.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 547.72 749.10 Td (or ) Tj ET Q q 0 0 0 rg BT 559.37 749.10 Td (data ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (exclusivity\) ) Tj ET Q q 0 0 0 rg BT 85.61 737.10 Td (occurred ) Tj ET Q q 0 0 0 rg BT 122.99 737.10 Td (or ) Tj ET Q q 0 0 0 rg BT 133.72 737.10 Td (is ) Tj ET Q q 0 0 0 rg BT 142.79 737.10 Td (currently ) Tj ET Q q 0 0 0 rg BT 181.29 737.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 222.01 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.19 737.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 256.80 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 266.98 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 281.60 737.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 304.28 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 318.90 737.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 334.63 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 351.47 737.10 Td (Japan. ) Tj ET Q q 0 0 0 rg BT 378.97 737.10 Td (W) Tj ET Q q 0 0 0 rg BT 387.60 737.10 Td (e ) Tj ET Q q 0 0 0 rg BT 394.44 737.10 Td (also ) Tj ET Q q 0 0 0 rg BT 412.95 737.10 Td (sell ) Tj ET Q q 0 0 0 rg BT 429.24 737.10 Td (our ) Tj ET Q q 0 0 0 rg BT 444.97 737.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 508.45 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 545.29 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 555.47 737.10 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (countries; ) Tj ET Q q 0 0 0 rg BT 78.13 725.10 Td (however) Tj ET Q q 0 0 0 rg BT 112.16 725.10 Td (, ) Tj ET Q q 0 0 0 rg BT 117.36 725.10 Td (data ) Tj ET Q q 0 0 0 rg BT 136.71 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 146.07 725.10 Td (not ) Tj ET Q q 0 0 0 rg BT 161.55 725.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 199.79 725.10 Td (on ) Tj ET Q q 0 0 0 rg BT 212.49 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 219.63 725.10 Td (country-by-country ) Tj ET Q q 0 0 0 rg BT 300.08 725.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 322.77 725.10 Td (because ) Tj ET Q q 0 0 0 rg BT 357.11 725.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 400.36 725.10 Td (country ) Tj ET Q q 0 0 0 rg BT 433.61 725.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 471.84 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 486.74 725.10 Td (not ) Tj ET Q q 0 0 0 rg BT 502.22 725.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 547.13 725.10 Td (outside ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.53 713.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 73.12 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 87.65 713.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 103.29 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 120.03 713.10 Td (Japan. ) Tj ET Q q 0 0 0 rg BT 147.61 713.10 Td (In ) Tj ET Q q 0 0 0 rg BT 158.25 713.10 Td (many ) Tj ET Q q 0 0 0 rg BT 182.78 713.10 Td (instances, ) Tj ET Q q 0 0 0 rg BT 224.24 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 238.77 713.10 Td (basic ) Tj ET Q q 0 0 0 rg BT 261.63 713.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 307.82 713.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 325.69 713.10 Td (date ) Tj ET Q q 0 0 0 rg BT 344.65 713.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 368.63 713.10 Td (below ) Tj ET Q q 0 0 0 rg BT 395.38 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 404.35 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 418.88 713.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 461.73 713.10 Td (date ) Tj ET Q q 0 0 0 rg BT 480.70 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 491.34 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 505.86 713.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 532.61 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 549.91 713.10 Td (claims ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.58 701.10 Td (active ) Tj ET Q q 0 0 0 rg BT 76.83 701.10 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 119.74 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 130.43 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 145.02 701.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 165.72 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 176.42 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 191.00 701.10 Td (method ) Tj ET Q q 0 0 0 rg BT 223.36 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 234.06 701.10 Td (using ) Tj ET Q q 0 0 0 rg BT 258.10 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 272.68 701.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 293.38 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 307.41 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 322.00 701.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 361.57 701.10 Td (indication, ) Tj ET Q q 0 0 0 rg BT 406.43 701.10 Td (if ) Tj ET Q q 0 0 0 rg BT 414.91 701.10 Td (there ) Tj ET Q q 0 0 0 rg BT 437.26 701.10 Td (is ) Tj ET Q q 0 0 0 rg BT 446.30 701.10 Td (only ) Tj ET Q q 0 0 0 rg BT 466.44 701.10 Td (one ) Tj ET Q q 0 0 0 rg BT 483.25 701.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 522.83 701.10 Td (indication. ) Tj ET Q q 0 0 0 rg BT 567.68 701.10 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (some ) Tj ET Q q 0 0 0 rg BT 59.51 689.10 Td (instances, ) Tj ET Q q 0 0 0 rg BT 101.08 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 115.70 689.10 Td (basic ) Tj ET Q q 0 0 0 rg BT 138.65 689.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 184.94 689.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 202.91 689.10 Td (date ) Tj ET Q q 0 0 0 rg BT 221.97 689.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 246.04 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 256.23 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 270.85 689.10 Td (chart ) Tj ET Q q 0 0 0 rg BT 293.24 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 302.32 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 316.94 689.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 359.89 689.10 Td (date ) Tj ET Q q 0 0 0 rg BT 378.95 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 389.69 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 404.31 689.10 Td (data ) Tj ET Q q 0 0 0 rg BT 423.37 689.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 469.66 689.10 Td (period. ) Tj ET Q q 0 0 0 rg BT 500.11 689.10 Td (In ) Tj ET Q q 0 0 0 rg BT 510.85 689.10 Td (situations ) Tj ET Q q 0 0 0 rg BT 551.59 689.10 Td (where ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (there ) Tj ET Q q 0 0 0 rg BT 58.23 677.10 Td (is ) Tj ET Q q 0 0 0 rg BT 67.14 677.10 Td (only ) Tj ET Q q 0 0 0 rg BT 87.16 677.10 Td (data ) Tj ET Q q 0 0 0 rg BT 106.06 677.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 152.19 677.10 Td (without ) Tj ET Q q 0 0 0 rg BT 184.99 677.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 211.67 677.10 Td (protection, ) Tj ET Q q 0 0 0 rg BT 256.95 677.10 Td (a ) Tj ET Q q 0 0 0 rg BT 263.63 677.10 Td (competitor ) Tj ET Q q 0 0 0 rg BT 309.20 677.10 Td (could ) Tj ET Q q 0 0 0 rg BT 333.66 677.10 Td (seek ) Tj ET Q q 0 0 0 rg BT 353.67 677.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 397.01 677.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 434.24 677.10 Td (by ) Tj ET Q q 0 0 0 rg BT 446.48 677.10 Td (submitting ) Tj ET Q q 0 0 0 rg BT 491.51 677.10 Td (its ) Tj ET Q q 0 0 0 rg BT 503.20 677.10 Td (own ) Tj ET Q q 0 0 0 rg BT 522.67 677.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 554.34 677.10 Td (study ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (data ) Tj ET Q q 0 0 0 rg BT 55.16 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 65.43 665.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 92.93 665.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 135.97 665.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 173.46 665.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 195.39 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 205.67 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 220.39 665.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 263.43 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 274.26 665.10 Td (data ) Tj ET Q q 0 0 0 rg BT 293.42 665.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 336.65 665.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 641.10 Td (e ) Tj ET Q q 0 0 0 rg BT 52.38 641.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 89.00 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 104.52 641.10 Td (market ) Tj ET Q q 0 0 0 rg BT 135.59 641.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 182.77 641.10 Td (period ) Tj ET Q q 0 0 0 rg BT 211.62 641.10 Td (for ) Tj ET Q q 0 0 0 rg BT 226.58 641.10 Td (each ) Tj ET Q q 0 0 0 rg BT 248.20 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 259.83 641.10 Td (our ) Tj ET Q q 0 0 0 rg BT 276.46 641.10 Td (products ) Tj ET Q q 0 0 0 rg BT 314.20 641.10 Td (for ) Tj ET Q q 0 0 0 rg BT 329.17 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 344.69 641.10 Td (purpose ) Tj ET Q q 0 0 0 rg BT 379.65 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 391.28 641.10 Td (business ) Tj ET Q q 0 0 0 rg BT 428.47 641.10 Td (planning ) Tj ET Q q 0 0 0 rg BT 466.77 641.10 Td (only) Tj ET Q q 0 0 0 rg BT 483.90 641.10 Td (. ) Tj ET Q q 0 0 0 rg BT 489.46 641.10 Td (The ) Tj ET Q q 0 0 0 rg BT 508.31 641.10 Td (length ) Tj ET Q q 0 0 0 rg BT 536.61 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 548.24 641.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 81.53 629.10 Td (for ) Tj ET Q q 0 0 0 rg BT 94.84 629.10 Td (any ) Tj ET Q q 0 0 0 rg BT 110.92 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 120.90 629.10 Td (our ) Tj ET Q q 0 0 0 rg BT 135.88 629.10 Td (products ) Tj ET Q q 0 0 0 rg BT 171.97 629.10 Td (is ) Tj ET Q q 0 0 0 rg BT 180.28 629.10 Td (impossible ) Tj ET Q q 0 0 0 rg BT 225.27 629.10 Td (to ) Tj ET Q q 0 0 0 rg BT 234.69 629.10 Td (predict ) Tj ET Q q 0 0 0 rg BT 264.11 629.10 Td (with ) Tj ET Q q 0 0 0 rg BT 283.53 629.10 Td (certainty ) Tj ET Q q 0 0 0 rg BT 320.16 629.10 Td (because ) Tj ET Q q 0 0 0 rg BT 353.45 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 363.43 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 377.30 629.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 413.38 629.10 Td (interaction ) Tj ET Q q 0 0 0 rg BT 457.78 629.10 Td (between ) Tj ET Q q 0 0 0 rg BT 492.75 629.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 518.83 629.10 Td (and ) Tj ET Q q 0 0 0 rg BT 534.92 629.10 Td (regulatory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (forms ) Tj ET Q q 0 0 0 rg BT 62.14 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 73.29 617.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 119.98 617.10 Td (and ) Tj ET Q q 0 0 0 rg BT 137.24 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 152.27 617.10 Td (inherent ) Tj ET Q q 0 0 0 rg BT 187.84 617.10 Td (uncertainties ) Tj ET Q q 0 0 0 rg BT 241.75 617.10 Td (regarding ) Tj ET Q q 0 0 0 rg BT 282.88 617.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 310.12 617.10 Td (litigation. ) Tj ET Q q 0 0 0 rg BT 351.34 617.10 Td (There ) Tj ET Q q 0 0 0 rg BT 377.47 617.10 Td (can ) Tj ET Q q 0 0 0 rg BT 394.16 617.10 Td (be ) Tj ET Q q 0 0 0 rg BT 406.42 617.10 Td (no ) Tj ET Q q 0 0 0 rg BT 419.23 617.10 Td (assurance ) Tj ET Q q 0 0 0 rg BT 460.91 617.10 Td (that ) Tj ET Q q 0 0 0 rg BT 478.72 617.10 Td (a ) Tj ET Q q 0 0 0 rg BT 485.97 617.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 527.10 617.10 Td (product ) Tj ET Q q 0 0 0 rg BT 560.46 617.10 Td (will ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (enjoy ) Tj ET Q q 0 0 0 rg BT 60.72 605.10 Td (market ) Tj ET Q q 0 0 0 rg BT 90.98 605.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 137.36 605.10 Td (for ) Tj ET Q q 0 0 0 rg BT 151.52 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 166.24 605.10 Td (full ) Tj ET Q q 0 0 0 rg BT 182.63 605.10 Td (period ) Tj ET Q q 0 0 0 rg BT 210.67 605.10 Td (of ) Tj ET Q q 0 0 0 rg BT 221.50 605.10 Td (time ) Tj ET Q q 0 0 0 rg BT 241.78 605.10 Td (that ) Tj ET Q q 0 0 0 rg BT 259.27 605.10 Td (appears ) Tj ET Q q 0 0 0 rg BT 292.31 605.10 Td (in ) Tj ET Q q 0 0 0 rg BT 302.59 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 317.30 605.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 353.12 605.10 Td (or ) Tj ET Q q 0 0 0 rg BT 363.95 605.10 Td (that ) Tj ET Q q 0 0 0 rg BT 381.45 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 396.17 605.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 442.55 605.10 Td (will ) Tj ET Q q 0 0 0 rg BT 460.60 605.10 Td (be ) Tj ET Q q 0 0 0 rg BT 472.54 605.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 503.37 605.10 Td (to ) Tj ET Q q 0 0 0 rg BT 513.65 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 528.37 605.10 Td (estimate.) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 564.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 564.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 564.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 564.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 564.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 564.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 564.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 564.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 540.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 540.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 540.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 540.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 540.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 540.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 540.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 540.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 516.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 516.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 516.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 516.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 516.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 516.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 516.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 516.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 492.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 492.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 492.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 492.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 492.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 492.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 492.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 492.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 475.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 475.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 475.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 475.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 475.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 475.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 475.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 475.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 451.60 280.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 451.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 451.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 451.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 451.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 451.60 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 451.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 451.60 38.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 427.60 280.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 427.60 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 427.60 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 427.60 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 442.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 427.60 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 484.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 488.50 427.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 427.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 427.60 38.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 581.6 m 358.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 358.5 581.6 m 362.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 362.5 581.6 m 400.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 400.5 581.6 m 404.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 581.6 m 442.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 581.6 m 484.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 581.6 m 488.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 488.5 581.6 m 534.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 534.5 581.6 m 538.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 538.5 581.6 m 576.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 564.6 m 358.5 564.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 362.5 581.6 m 400.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 362.5 564.6 m 400.5 564.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 400.5 581.6 m 404.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 581.6 m 442.5 581.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 564.6 m 442.5 564.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 564.6 m 484.5 564.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 488.5 564.6 m 534.5 564.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 538.5 564.6 m 576.5 564.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 585.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 335.10 585.83 Td (T) Tj ET Q q 0 0 0 rg BT 340.07 585.83 Td (otal Revenues by Pr) Tj ET Q q 0 0 0 rg BT 407.84 585.83 Td (oduct) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 484.20 585.83 Td (Estimated LOE) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 568.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 331.00 568.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 373.00 568.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 415.00 568.83 Td (2015) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 457.85 568.83 Td (U.S.) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 505.40 568.83 Td (EU) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 546.55 568.83 Td (Japan) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 39.00 556.00 Td (Prioritized Brands) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 543.85 Td (Opdivo \(nivolumab\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 113.98 547.93 Td (\(a\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 323.00 543.86 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 543.86 Td (4,948) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 365.00 543.86 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 543.86 Td (3,774) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 407.00 543.86 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 425.50 543.86 Td (942) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 543.86 Td (2027) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 543.86 Td (2026) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 543.86 Td (2031) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 531.85 Td (Eliquis \(apixaban\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 108.49 535.93 Td (\(b\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 531.86 Td (4,872) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 531.86 Td (3,343) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 531.86 Td (1,860) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 531.86 Td (2026) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 531.86 Td (2026) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 531.86 Td (2026) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 519.85 Td (Or) Tj ET Q q 0 0 0 rg BT 48.67 519.85 Td (encia \(abatacept\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 114.14 523.93 Td (\(c\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 519.86 Td (2,479) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 519.86 Td (2,265) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 519.86 Td (1,885) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 519.86 Td (2019) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 519.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 519.86 Td (2018) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 507.85 Td (Sprycel \(dasatinib\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 109.98 511.93 Td (\(d\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 507.86 Td (2,005) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 507.86 Td (1,824) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 507.86 Td (1,620) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 507.86 Td (2020) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 522.55 507.86 Td (^^) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 507.86 Td (2021) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 495.85 Td (Y) Tj ET Q q 0 0 0 rg BT 43.18 495.85 Td (ervoy \(ipilimumab\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 114.66 499.93 Td (\(e\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 495.86 Td (1,244) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 495.86 Td (1,053) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 495.86 Td (1,126) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 495.86 Td (2025) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 495.86 Td (2025) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 495.86 Td (2025) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 483.85 Td (Empliciti \(elotuzumab\) ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 123.99 487.93 Td (\(f\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 483.86 Td (231) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 383.50 483.86 Td (150) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 434.50 483.86 Td (3) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 483.86 Td (2027) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 483.86 Td (2026) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 483.86 Td (2024) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 39.00 467.00 Td (Established Brands) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 454.85 Td (Baraclude \(entecavir\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 454.86 Td (1,052) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 454.86 Td (1,192) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 454.86 Td (1,312) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 454.86 Td (2014) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 492.30 454.86 Td (201) Tj ET Q q 0 0 0 rg BT 505.63 454.86 Td (1-2016) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 454.86 Td (2016) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 442.85 Td (Sustiva \(efavir) Tj ET Q q 0 0 0 rg BT 90.90 442.85 Td (enz\) Franchise ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 146.89 446.93 Td (\(g\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 442.86 Td (729) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 442.86 Td (1,065) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 442.86 Td (1,252) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 442.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 442.86 Td (2013) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 562.80 442.86 Td (++) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 430.85 Td (Reyataz \(atazanavir sulfate\) Franchise ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 181.48 434.93 Td (\(h\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 430.86 Td (698) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 383.50 430.86 Td (912) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 430.86 Td (1,139) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 430.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 492.00 430.86 Td (2017-2019) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 430.86 Td (2019) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 39.00 418.86 Td (Hepatitis C Franchise) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 116.99 418.86 Td ( ) Tj ET Q BT /F3 9.00 Tf ET BT /F3 5.85 Tf ET q 0 0 0 rg BT 119.24 422.94 Td (\(i\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 418.86 Td (406) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 376.75 418.86 Td (1,578) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.75 418.86 Td (1,603) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 463.00 418.86 Td (2028) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 513.00 418.86 Td (2027) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 418.86 Td (2028) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 403.50 Td (Note: ) Tj ET Q q 0 0 0 rg BT 55.73 403.50 Td (The ) Tj ET Q q 0 0 0 rg BT 70.28 403.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 103.05 403.50 Td (year ) Tj ET Q q 0 0 0 rg BT 118.92 403.50 Td (of ) Tj ET Q q 0 0 0 rg BT 127.70 403.50 Td (basic ) Tj ET Q q 0 0 0 rg BT 146.24 403.50 Td (LOE ) Tj ET Q q 0 0 0 rg BT 163.91 403.50 Td (in ) Tj ET Q q 0 0 0 rg BT 172.24 403.50 Td (the ) Tj ET Q q 0 0 0 rg BT 184.12 403.50 Td (table ) Tj ET Q q 0 0 0 rg BT 201.78 403.50 Td (above ) Tj ET Q q 0 0 0 rg BT 222.99 403.50 Td (includes ) Tj ET Q q 0 0 0 rg BT 251.76 403.50 Td (granted ) Tj ET Q q 0 0 0 rg BT 277.86 403.50 Td (extensions ) Tj ET Q q 0 0 0 rg BT 313.74 403.50 Td (such ) Tj ET Q q 0 0 0 rg BT 330.52 403.50 Td (as ) Tj ET Q q 0 0 0 rg BT 339.29 403.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 360.95 403.50 Td (term ) Tj ET Q q 0 0 0 rg BT 377.72 403.50 Td (restoration ) Tj ET Q q 0 0 0 rg BT 414.04 403.50 Td (\(PTR\) ) Tj ET Q q 0 0 0 rg BT 436.15 403.50 Td (and/or ) Tj ET Q q 0 0 0 rg BT 458.70 403.50 Td (six ) Tj ET Q q 0 0 0 rg BT 470.15 403.50 Td (months ) Tj ET Q q 0 0 0 rg BT 495.82 403.50 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 525.91 403.50 Td (extensions ) Tj ET Q q 0 0 0 rg BT 561.79 403.50 Td (only ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 393.90 Td (if ) Tj ET Q q 0 0 0 rg BT 42.63 393.90 Td (obtained. ) Tj ET Q q 0 0 0 rg BT 73.79 393.90 Td (There ) Tj ET Q q 0 0 0 rg BT 94.18 393.90 Td (may ) Tj ET Q q 0 0 0 rg BT 109.69 393.90 Td (be ) Tj ET Q q 0 0 0 rg BT 118.99 393.90 Td (other ) Tj ET Q q 0 0 0 rg BT 137.16 393.90 Td (later) Tj ET Q q 0 0 0 rg BT 151.21 393.90 Td (-expiring ) Tj ET Q q 0 0 0 rg BT 182.28 393.90 Td (patents ) Tj ET Q q 0 0 0 rg BT 206.68 393.90 Td (that ) Tj ET Q q 0 0 0 rg BT 220.42 393.90 Td (cover ) Tj ET Q q 0 0 0 rg BT 239.92 393.90 Td (particular ) Tj ET Q q 0 0 0 rg BT 272.31 393.90 Td (forms, ) Tj ET Q q 0 0 0 rg BT 294.71 393.90 Td (compositions, ) Tj ET Q q 0 0 0 rg BT 341.12 393.90 Td (methods ) Tj ET Q q 0 0 0 rg BT 369.97 393.90 Td (of ) Tj ET Q q 0 0 0 rg BT 378.38 393.90 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 428.76 393.90 Td (or ) Tj ET Q q 0 0 0 rg BT 437.17 393.90 Td (methods ) Tj ET Q q 0 0 0 rg BT 466.02 393.90 Td (of ) Tj ET Q q 0 0 0 rg BT 474.42 393.90 Td (using ) Tj ET Q q 0 0 0 rg BT 493.50 393.90 Td (the ) Tj ET Q q 0 0 0 rg BT 505.01 393.90 Td (drug ) Tj ET Q q 0 0 0 rg BT 521.42 393.90 Td (which ) Tj ET Q q 0 0 0 rg BT 542.71 393.90 Td (may ) Tj ET Q q 0 0 0 rg BT 558.22 393.90 Td (result ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 384.30 Td (in ) Tj ET Q q 0 0 0 rg BT 44.10 384.30 Td (a ) Tj ET Q q 0 0 0 rg BT 49.52 384.30 Td (favorable ) Tj ET Q q 0 0 0 rg BT 81.60 384.30 Td (market ) Tj ET Q q 0 0 0 rg BT 105.68 384.30 Td (position ) Tj ET Q q 0 0 0 rg BT 133.33 384.30 Td (for ) Tj ET Q q 0 0 0 rg BT 144.54 384.30 Td (our ) Tj ET Q q 0 0 0 rg BT 157.07 384.30 Td (products, ) Tj ET Q q 0 0 0 rg BT 188.50 384.30 Td (but ) Tj ET Q q 0 0 0 rg BT 200.59 384.30 Td (product ) Tj ET Q q 0 0 0 rg BT 226.90 384.30 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 263.88 384.30 Td (cannot ) Tj ET Q q 0 0 0 rg BT 287.08 384.30 Td (be ) Tj ET Q q 0 0 0 rg BT 296.50 384.30 Td (predicted ) Tj ET Q q 0 0 0 rg BT 328.14 384.30 Td (or ) Tj ET Q q 0 0 0 rg BT 336.67 384.30 Td (assured. ) Tj ET Q q 0 0 0 rg BT 364.54 384.30 Td (Regulatory ) Tj ET Q q 0 0 0 rg BT 401.96 384.30 Td (data ) Tj ET Q q 0 0 0 rg BT 417.16 384.30 Td (protection ) Tj ET Q q 0 0 0 rg BT 451.46 384.30 Td (\(RDP\) ) Tj ET Q q 0 0 0 rg BT 474.23 384.30 Td (may ) Tj ET Q q 0 0 0 rg BT 489.87 384.30 Td (be ) Tj ET Q q 0 0 0 rg BT 499.30 384.30 Td (obtained ) Tj ET Q q 0 0 0 rg BT 528.72 384.30 Td (as ) Tj ET Q q 0 0 0 rg BT 537.25 384.30 Td (described ) Tj ET Q q 0 0 0 rg BT 569.78 384.30 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 374.70 Td (more ) Tj ET Q q 0 0 0 rg BT 54.84 374.70 Td (detail ) Tj ET Q q 0 0 0 rg BT 75.02 374.70 Td (in ) Tj ET Q q 0 0 0 rg BT 83.65 374.70 Td (the ) Tj ET Q q 0 0 0 rg BT 95.83 374.70 Td ("—Products, ) Tj ET Q q 0 0 0 rg BT 139.50 374.70 Td (Intellectual ) Tj ET Q q 0 0 0 rg BT 177.89 374.70 Td (Property ) Tj ET Q q 0 0 0 rg BT 207.85 374.70 Td (and ) Tj ET Q q 0 0 0 rg BT 221.81 374.70 Td (Product ) Tj ET Q q 0 0 0 rg BT 249.10 374.70 Td (Exclusivity" ) Tj ET Q q 0 0 0 rg BT 291.22 374.70 Td (section. ) Tj ET Q q 0 0 0 rg BT 318.28 374.70 Td (References ) Tj ET Q q 0 0 0 rg BT 356.22 374.70 Td (to ) Tj ET Q q 0 0 0 rg BT 364.85 374.70 Td (the ) Tj ET Q q 0 0 0 rg BT 377.03 374.70 Td (EU ) Tj ET Q q 0 0 0 rg BT 390.10 374.70 Td (throughout ) Tj ET Q q 0 0 0 rg BT 427.62 374.70 Td (this ) Tj ET Q q 0 0 0 rg BT 441.59 374.70 Td (Form ) Tj ET Q q 0 0 0 rg BT 461.33 374.70 Td (10-K ) Tj ET Q q 0 0 0 rg BT 480.18 374.70 Td (include ) Tj ET Q q 0 0 0 rg BT 506.13 374.70 Td (all ) Tj ET Q q 0 0 0 rg BT 516.54 374.70 Td (EU ) Tj ET Q q 0 0 0 rg BT 529.61 374.70 Td (member ) Tj ET Q q 0 0 0 rg BT 558.23 374.70 Td (states ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (during ) Tj ET Q q 0 0 0 rg BT 58.83 365.10 Td (the ) Tj ET Q q 0 0 0 rg BT 70.55 365.10 Td (year ) Tj ET Q q 0 0 0 rg BT 86.26 365.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 107.30 365.10 Td (December ) Tj ET Q q 0 0 0 rg BT 142.11 365.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 154.05 365.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 174.00 365.10 Td (Basic ) Tj ET Q q 0 0 0 rg BT 193.71 365.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 215.21 365.10 Td (applications ) Tj ET Q q 0 0 0 rg BT 255.80 365.10 Td (may ) Tj ET Q q 0 0 0 rg BT 271.52 365.10 Td (not ) Tj ET Q q 0 0 0 rg BT 283.69 365.10 Td (have ) Tj ET Q q 0 0 0 rg BT 300.73 365.10 Td (been ) Tj ET Q q 0 0 0 rg BT 317.78 365.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 334.38 365.10 Td (in ) Tj ET Q q 0 0 0 rg BT 342.55 365.10 Td (all ) Tj ET Q q 0 0 0 rg BT 352.49 365.10 Td (current ) Tj ET Q q 0 0 0 rg BT 377.08 365.10 Td (member ) Tj ET Q q 0 0 0 rg BT 405.24 365.10 Td (states ) Tj ET Q q 0 0 0 rg BT 424.95 365.10 Td (for ) Tj ET Q q 0 0 0 rg BT 436.22 365.10 Td (all ) Tj ET Q q 0 0 0 rg BT 446.16 365.10 Td (of ) Tj ET Q q 0 0 0 rg BT 454.77 365.10 Td (the ) Tj ET Q q 0 0 0 rg BT 466.49 365.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 485.76 365.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 517.26 365.10 Td (In ) Tj ET Q q 0 0 0 rg BT 525.87 365.10 Td (some ) Tj ET Q q 0 0 0 rg BT 544.70 365.10 Td (instances, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 355.50 Td (the ) Tj ET Q q 0 0 0 rg BT 47.77 355.50 Td (date ) Tj ET Q q 0 0 0 rg BT 63.10 355.50 Td (of ) Tj ET Q q 0 0 0 rg BT 71.76 355.50 Td (basic ) Tj ET Q q 0 0 0 rg BT 90.20 355.50 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 127.30 355.50 Td (loss ) Tj ET Q q 0 0 0 rg BT 141.75 355.50 Td (will ) Tj ET Q q 0 0 0 rg BT 156.20 355.50 Td (be ) Tj ET Q q 0 0 0 rg BT 165.75 355.50 Td (dif) Tj ET Q q 0 0 0 rg BT 174.49 355.50 Td (ferent ) Tj ET Q q 0 0 0 rg BT 195.14 355.50 Td (in ) Tj ET Q q 0 0 0 rg BT 203.37 355.50 Td (various ) Tj ET Q q 0 0 0 rg BT 228.92 355.50 Td (EU ) Tj ET Q q 0 0 0 rg BT 241.58 355.50 Td (member ) Tj ET Q q 0 0 0 rg BT 269.79 355.50 Td (states.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 339.90 Td (++ ) Tj ET Q q 0 0 0 rg BT 54.00 339.90 Td (W) Tj ET Q q 0 0 0 rg BT 60.91 339.90 Td (e ) Tj ET Q q 0 0 0 rg BT 66.46 339.90 Td (do ) Tj ET Q q 0 0 0 rg BT 76.46 339.90 Td (not ) Tj ET Q q 0 0 0 rg BT 88.68 339.90 Td (currently ) Tj ET Q q 0 0 0 rg BT 119.56 339.90 Td (market ) Tj ET Q q 0 0 0 rg BT 143.77 339.90 Td (the ) Tj ET Q q 0 0 0 rg BT 155.54 339.90 Td (product ) Tj ET Q q 0 0 0 rg BT 181.98 339.90 Td (in ) Tj ET Q q 0 0 0 rg BT 190.20 339.90 Td (the ) Tj ET Q q 0 0 0 rg BT 201.98 339.90 Td (country ) Tj ET Q q 0 0 0 rg BT 228.41 339.90 Td (or ) Tj ET Q q 0 0 0 rg BT 237.08 339.90 Td (region ) Tj ET Q q 0 0 0 rg BT 259.52 339.90 Td (indicated.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 330.30 Td (^^ ) Tj ET Q q 0 0 0 rg BT 54.00 330.30 Td (In ) Tj ET Q q 0 0 0 rg BT 62.17 330.30 Td (February ) Tj ET Q q 0 0 0 rg BT 92.54 330.30 Td (2017, ) Tj ET Q q 0 0 0 rg BT 112.05 330.30 Td (the ) Tj ET Q q 0 0 0 rg BT 123.32 330.30 Td (EPO ) Tj ET Q q 0 0 0 rg BT 139.93 330.30 Td (Board ) Tj ET Q q 0 0 0 rg BT 160.99 330.30 Td (of ) Tj ET Q q 0 0 0 rg BT 168.82 330.30 Td (Appeal ) Tj ET Q q 0 0 0 rg BT 193.42 330.30 Td (revoked ) Tj ET Q q 0 0 0 rg BT 220.69 330.30 Td (the ) Tj ET Q q 0 0 0 rg BT 231.96 330.30 Td (EU ) Tj ET Q q 0 0 0 rg BT 244.13 330.30 Td (composition ) Tj ET Q q 0 0 0 rg BT 285.18 330.30 Td (of ) Tj ET Q q 0 0 0 rg BT 293.35 330.30 Td (matter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 313.78 330.30 Td ( ) Tj ET Q q 0 0 0 rg BT 315.28 330.30 Td (\() Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 317.95 330.30 Td (COM\) ) Tj ET Q q 0 0 0 rg BT 340.34 330.30 Td (patent. ) Tj ET Q q 0 0 0 rg BT 363.39 330.30 Td (In ) Tj ET Q q 0 0 0 rg BT 371.55 330.30 Td (February ) Tj ET Q q 0 0 0 rg BT 401.93 330.30 Td (2017, ) Tj ET Q q 0 0 0 rg BT 421.43 330.30 Td (the ) Tj ET Q q 0 0 0 rg BT 432.71 330.30 Td (EPO ) Tj ET Q q 0 0 0 rg BT 449.32 330.30 Td (Board ) Tj ET Q q 0 0 0 rg BT 470.37 330.30 Td (of ) Tj ET Q q 0 0 0 rg BT 478.21 330.30 Td (Appeal ) Tj ET Q q 0 0 0 rg BT 502.81 330.30 Td (reversed ) Tj ET Q q 0 0 0 rg BT 531.41 330.30 Td (and ) Tj ET Q q 0 0 0 rg BT 544.46 330.30 Td (remanded ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 320.70 Td (an ) Tj ET Q q 0 0 0 rg BT 63.17 320.70 Td (invalidity ) Tj ET Q q 0 0 0 rg BT 95.46 320.70 Td (decision ) Tj ET Q q 0 0 0 rg BT 123.74 320.70 Td (to ) Tj ET Q q 0 0 0 rg BT 131.59 320.70 Td (the ) Tj ET Q q 0 0 0 rg BT 142.98 320.70 Td (use ) Tj ET Q q 0 0 0 rg BT 155.27 320.70 Td (of ) Tj ET Q q 0 0 0 rg BT 163.55 320.70 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 194.06 320.70 Td (to ) Tj ET Q q 0 0 0 rg BT 201.90 320.70 Td (treat ) Tj ET Q q 0 0 0 rg BT 217.74 320.70 Td (CML, ) Tj ET Q q 0 0 0 rg BT 238.69 320.70 Td (which ) Tj ET Q q 0 0 0 rg BT 259.87 320.70 Td (the ) Tj ET Q q 0 0 0 rg BT 271.26 320.70 Td (EPO’) Tj ET Q q 0 0 0 rg BT 288.60 320.70 Td (s ) Tj ET Q q 0 0 0 rg BT 293.33 320.70 Td (Opposition ) Tj ET Q q 0 0 0 rg BT 330.51 320.70 Td (Division ) Tj ET Q q 0 0 0 rg BT 359.70 320.70 Td (had ) Tj ET Q q 0 0 0 rg BT 372.87 320.70 Td (revoked ) Tj ET Q q 0 0 0 rg BT 400.26 320.70 Td (in ) Tj ET Q q 0 0 0 rg BT 408.10 320.70 Td (October ) Tj ET Q q 0 0 0 rg BT 435.49 320.70 Td (2012. ) Tj ET Q q 0 0 0 rg BT 455.11 320.70 Td (Refer ) Tj ET Q q 0 0 0 rg BT 474.50 320.70 Td (to ) Tj ET Q q 0 0 0 rg BT 482.34 320.70 Td ("Item ) Tj ET Q q 0 0 0 rg BT 501.89 320.70 Td (8. ) Tj ET Q q 0 0 0 rg BT 509.51 320.70 Td (Financial ) Tj ET Q q 0 0 0 rg BT 540.90 320.70 Td (Statements) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 311.10 Td (—Note ) Tj ET Q q 0 0 0 rg BT 79.55 311.10 Td (18. ) Tj ET Q q 0 0 0 rg BT 91.55 311.10 Td (Legal ) Tj ET Q q 0 0 0 rg BT 111.76 311.10 Td (Proceedings ) Tj ET Q q 0 0 0 rg BT 152.86 311.10 Td (and ) Tj ET Q q 0 0 0 rg BT 166.41 311.10 Td (Contingencies" ) Tj ET Q q 0 0 0 rg BT 217.45 311.10 Td (for ) Tj ET Q q 0 0 0 rg BT 228.78 311.10 Td (more ) Tj ET Q q 0 0 0 rg BT 247.21 311.10 Td (information.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 301.50 Td (\(a\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 301.50 Td (Opdivo) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 77.55 301.50 Td (: ) Tj ET Q q 0 0 0 rg BT 81.61 301.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 100.35 301.50 Td (jointly ) Tj ET Q q 0 0 0 rg BT 123.08 301.50 Td (owns ) Tj ET Q q 0 0 0 rg BT 141.81 301.50 Td (a ) Tj ET Q q 0 0 0 rg BT 147.20 301.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 168.59 301.50 Td (with ) Tj ET Q q 0 0 0 rg BT 184.65 301.50 Td (Ono ) Tj ET Q q 0 0 0 rg BT 200.27 301.50 Td (covering ) Tj ET Q q 0 0 0 rg BT 230.10 301.50 Td (nivolumab ) Tj ET Q q 0 0 0 rg BT 266.16 301.50 Td (as ) Tj ET Q q 0 0 0 rg BT 274.66 301.50 Td (a ) Tj ET Q q 0 0 0 rg BT 280.05 301.50 Td (COM ) Tj ET Q q 0 0 0 rg BT 300.12 301.50 Td (that ) Tj ET Q q 0 0 0 rg BT 313.95 301.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 338.89 301.50 Td (2027 ) Tj ET Q q 0 0 0 rg BT 356.73 301.50 Td (in ) Tj ET Q q 0 0 0 rg BT 364.80 301.50 Td (the ) Tj ET Q q 0 0 0 rg BT 376.41 301.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 392.48 301.50 Td (and ) Tj ET Q q 0 0 0 rg BT 405.87 301.50 Td (2026 ) Tj ET Q q 0 0 0 rg BT 423.71 301.50 Td (in ) Tj ET Q q 0 0 0 rg BT 431.77 301.50 Td (the ) Tj ET Q q 0 0 0 rg BT 443.38 301.50 Td (EU. ) Tj ET Q q 0 0 0 rg BT 457.89 301.50 Td (PTRs ) Tj ET Q q 0 0 0 rg BT 477.51 301.50 Td (have ) Tj ET Q q 0 0 0 rg BT 494.45 301.50 Td (been ) Tj ET Q q 0 0 0 rg BT 511.39 301.50 Td (filed, ) Tj ET Q q 0 0 0 rg BT 529.89 301.50 Td (and ) Tj ET Q q 0 0 0 rg BT 543.29 301.50 Td (if ) Tj ET Q q 0 0 0 rg BT 550.01 301.50 Td (granted, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 291.90 Td (will ) Tj ET Q q 0 0 0 rg BT 68.45 291.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 90.43 291.90 Td (in ) Tj ET Q q 0 0 0 rg BT 98.66 291.90 Td (2028 ) Tj ET Q q 0 0 0 rg BT 116.66 291.90 Td (in ) Tj ET Q q 0 0 0 rg BT 124.88 291.90 Td (the ) Tj ET Q q 0 0 0 rg BT 136.65 291.90 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 152.88 291.90 Td (and ) Tj ET Q q 0 0 0 rg BT 166.43 291.90 Td (2030 ) Tj ET Q q 0 0 0 rg BT 184.43 291.90 Td (in ) Tj ET Q q 0 0 0 rg BT 192.65 291.90 Td (the ) Tj ET Q q 0 0 0 rg BT 204.43 291.90 Td (EU. ) Tj ET Q q 0 0 0 rg BT 218.95 291.90 Td (The ) Tj ET Q q 0 0 0 rg BT 233.38 291.90 Td (COM ) Tj ET Q q 0 0 0 rg BT 253.61 291.90 Td (patent ) Tj ET Q q 0 0 0 rg BT 275.16 291.90 Td (covering ) Tj ET Q q 0 0 0 rg BT 305.14 291.90 Td (nivolumab ) Tj ET Q q 0 0 0 rg BT 341.36 291.90 Td (in ) Tj ET Q q 0 0 0 rg BT 349.59 291.90 Td (Japan ) Tj ET Q q 0 0 0 rg BT 369.80 291.90 Td (expires ) Tj ET Q q 0 0 0 rg BT 394.90 291.90 Td (in ) Tj ET Q q 0 0 0 rg BT 403.13 291.90 Td (2031 ) Tj ET Q q 0 0 0 rg BT 421.13 291.90 Td (including ) Tj ET Q q 0 0 0 rg BT 453.34 291.90 Td (the ) Tj ET Q q 0 0 0 rg BT 465.12 291.90 Td (granted ) Tj ET Q q 0 0 0 rg BT 491.11 291.90 Td (PTR.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 282.30 Td (\(b\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 282.30 Td (Eliquis) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 76.67 282.30 Td (: ) Tj ET Q q 0 0 0 rg BT 81.17 282.30 Td (The ) Tj ET Q q 0 0 0 rg BT 96.06 282.30 Td (LOE ) Tj ET Q q 0 0 0 rg BT 114.06 282.30 Td (above ) Tj ET Q q 0 0 0 rg BT 135.61 282.30 Td (is ) Tj ET Q q 0 0 0 rg BT 143.40 282.30 Td (based ) Tj ET Q q 0 0 0 rg BT 164.07 282.30 Td (upon ) Tj ET Q q 0 0 0 rg BT 182.52 282.30 Td (the ) Tj ET Q q 0 0 0 rg BT 194.74 282.30 Td (COM ) Tj ET Q q 0 0 0 rg BT 215.42 282.30 Td (patent ) Tj ET Q q 0 0 0 rg BT 237.42 282.30 Td (and ) Tj ET Q q 0 0 0 rg BT 251.43 282.30 Td (expires ) Tj ET Q q 0 0 0 rg BT 276.98 282.30 Td (in ) Tj ET Q q 0 0 0 rg BT 285.65 282.30 Td (2026 ) Tj ET Q q 0 0 0 rg BT 304.11 282.30 Td (in ) Tj ET Q q 0 0 0 rg BT 312.78 282.30 Td (the ) Tj ET Q q 0 0 0 rg BT 325.01 282.30 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 343.69 282.30 Td (EU ) Tj ET Q q 0 0 0 rg BT 356.80 282.30 Td (and ) Tj ET Q q 0 0 0 rg BT 370.80 282.30 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 393.47 282.30 Td (including ) Tj ET Q q 0 0 0 rg BT 426.14 282.30 Td (the ) Tj ET Q q 0 0 0 rg BT 438.37 282.30 Td (granted ) Tj ET Q q 0 0 0 rg BT 464.81 282.30 Td (PTR. ) Tj ET Q q 0 0 0 rg BT 483.93 282.30 Td (BMS ) Tj ET Q q 0 0 0 rg BT 503.28 282.30 Td (received ) Tj ET Q q 0 0 0 rg BT 532.82 282.30 Td (Paragraph ) Tj ET Q q 0 0 0 rg BT 567.71 282.30 Td (IV) Tj ET Q q 0 0 0 rg BT 576.00 282.30 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 272.70 Td (certifications ) Tj ET Q q 0 0 0 rg BT 98.42 272.70 Td (from ) Tj ET Q q 0 0 0 rg BT 116.64 272.70 Td (twenty-five ) Tj ET Q q 0 0 0 rg BT 156.18 272.70 Td (aNDA) Tj ET Q q 0 0 0 rg BT 176.62 272.70 Td ( ) Tj ET Q q 0 0 0 rg BT 179.29 272.70 Td (filers ) Tj ET Q q 0 0 0 rg BT 198.39 272.70 Td (and ) Tj ET Q q 0 0 0 rg BT 212.61 272.70 Td (initiated ) Tj ET Q q 0 0 0 rg BT 241.49 272.70 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 258.38 272.70 Td (Hatch ) Tj ET Q q 0 0 0 rg BT 279.96 272.70 Td (W) Tj ET Q q 0 0 0 rg BT 286.87 272.70 Td (axman ) Tj ET Q q 0 0 0 rg BT 310.86 272.70 Td (patent ) Tj ET Q q 0 0 0 rg BT 333.07 272.70 Td (litigation ) Tj ET Q q 0 0 0 rg BT 364.62 272.70 Td (in ) Tj ET Q q 0 0 0 rg BT 372.92 272.70 Td (April ) Tj ET Q q 0 0 0 rg BT 392.48 272.70 Td (2017. ) Tj ET Q q 0 0 0 rg BT 413.14 272.70 Td (BMS ) Tj ET Q q 0 0 0 rg BT 432.71 272.70 Td (has ) Tj ET Q q 0 0 0 rg BT 446.04 272.70 Td (settled ) Tj ET Q q 0 0 0 rg BT 469.59 272.70 Td (with ) Tj ET Q q 0 0 0 rg BT 486.47 272.70 Td (several ) Tj ET Q q 0 0 0 rg BT 511.79 272.70 Td (aNDA) Tj ET Q q 0 0 0 rg BT 532.23 272.70 Td ( ) Tj ET Q q 0 0 0 rg BT 534.90 272.70 Td (filers. ) Tj ET Q q 0 0 0 rg BT 556.00 272.70 Td (In ) Tj ET Q q 0 0 0 rg BT 565.33 272.70 Td (EU ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 263.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 85.32 263.10 Td (where ) Tj ET Q q 0 0 0 rg BT 106.87 263.10 Td (there ) Tj ET Q q 0 0 0 rg BT 124.86 263.10 Td (is ) Tj ET Q q 0 0 0 rg BT 132.19 263.10 Td (no ) Tj ET Q q 0 0 0 rg BT 142.19 263.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 168.18 263.10 Td (PTR, ) Tj ET Q q 0 0 0 rg BT 186.85 263.10 Td (the ) Tj ET Q q 0 0 0 rg BT 198.63 263.10 Td (COM ) Tj ET Q q 0 0 0 rg BT 218.85 263.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 240.40 263.10 Td (expires ) Tj ET Q q 0 0 0 rg BT 265.50 263.10 Td (in ) Tj ET Q q 0 0 0 rg BT 273.72 263.10 Td (2022.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 253.50 Td (\(c\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 253.50 Td (Or) Tj ET Q q 0 0 0 rg BT 62.59 253.50 Td (encia) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 79.92 253.50 Td (: ) Tj ET Q q 0 0 0 rg BT 84.30 253.50 Td (The ) Tj ET Q q 0 0 0 rg BT 99.06 253.50 Td (COM ) Tj ET Q q 0 0 0 rg BT 119.62 253.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 141.49 253.50 Td (including ) Tj ET Q q 0 0 0 rg BT 174.03 253.50 Td (PTR ) Tj ET Q q 0 0 0 rg BT 191.03 253.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 216.46 253.50 Td (in ) Tj ET Q q 0 0 0 rg BT 225.01 253.50 Td (2019 ) Tj ET Q q 0 0 0 rg BT 243.33 253.50 Td (in ) Tj ET Q q 0 0 0 rg BT 251.88 253.50 Td (the ) Tj ET Q q 0 0 0 rg BT 263.98 253.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 280.54 253.50 Td (and ) Tj ET Q q 0 0 0 rg BT 294.41 253.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 312.74 253.50 Td (in ) Tj ET Q q 0 0 0 rg BT 321.29 253.50 Td (the ) Tj ET Q q 0 0 0 rg BT 333.39 253.50 Td (EU. ) Tj ET Q q 0 0 0 rg BT 348.38 253.50 Td (In ) Tj ET Q q 0 0 0 rg BT 357.37 253.50 Td (the ) Tj ET Q q 0 0 0 rg BT 369.47 253.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 386.02 253.50 Td (and ) Tj ET Q q 0 0 0 rg BT 399.90 253.50 Td (EU, ) Tj ET Q q 0 0 0 rg BT 414.89 253.50 Td (the ) Tj ET Q q 0 0 0 rg BT 426.99 253.50 Td (method ) Tj ET Q q 0 0 0 rg BT 453.31 253.50 Td (of ) Tj ET Q q 0 0 0 rg BT 462.30 253.50 Td (use ) Tj ET Q q 0 0 0 rg BT 475.29 253.50 Td (patents ) Tj ET Q q 0 0 0 rg BT 500.28 253.50 Td (covering ) Tj ET Q q 0 0 0 rg BT 530.59 253.50 Td (all ) Tj ET Q q 0 0 0 rg BT 540.91 253.50 Td (indications ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 243.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 76.52 243.90 Td (in ) Tj ET Q q 0 0 0 rg BT 85.28 243.90 Td (2021. ) Tj ET Q q 0 0 0 rg BT 105.82 243.90 Td (In ) Tj ET Q q 0 0 0 rg BT 115.02 243.90 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 137.77 243.90 Td (LOE ) Tj ET Q q 0 0 0 rg BT 155.85 243.90 Td (is ) Tj ET Q q 0 0 0 rg BT 163.72 243.90 Td (based ) Tj ET Q q 0 0 0 rg BT 184.47 243.90 Td (on ) Tj ET Q q 0 0 0 rg BT 195.01 243.90 Td (RDP) Tj ET Q q 0 0 0 rg BT 210.27 243.90 Td ( ) Tj ET Q q 0 0 0 rg BT 212.81 243.90 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 247.39 243.90 Td (, ) Tj ET Q q 0 0 0 rg BT 251.93 243.90 Td (which ) Tj ET Q q 0 0 0 rg BT 274.02 243.90 Td (expires ) Tj ET Q q 0 0 0 rg BT 299.65 243.90 Td (in ) Tj ET Q q 0 0 0 rg BT 308.41 243.90 Td (2018. ) Tj ET Q q 0 0 0 rg BT 328.95 243.90 Td (Formulation ) Tj ET Q q 0 0 0 rg BT 371.04 243.90 Td (and ) Tj ET Q q 0 0 0 rg BT 385.12 243.90 Td (additional ) Tj ET Q q 0 0 0 rg BT 419.65 243.90 Td (patents ) Tj ET Q q 0 0 0 rg BT 444.84 243.90 Td (directed ) Tj ET Q q 0 0 0 rg BT 473.14 243.90 Td (to ) Tj ET Q q 0 0 0 rg BT 481.90 243.90 Td (abatacept ) Tj ET Q q 0 0 0 rg BT 514.63 243.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 537.16 243.90 Td (in ) Tj ET Q q 0 0 0 rg BT 545.91 243.90 Td (2026 ) Tj ET Q q 0 0 0 rg BT 564.45 243.90 Td (and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 234.30 Td (beyond. ) Tj ET Q q 0 0 0 rg BT 81.55 234.30 Td (BMS ) Tj ET Q q 0 0 0 rg BT 100.45 234.30 Td (is ) Tj ET Q q 0 0 0 rg BT 107.79 234.30 Td (not ) Tj ET Q q 0 0 0 rg BT 120.01 234.30 Td (aware ) Tj ET Q q 0 0 0 rg BT 141.10 234.30 Td (of ) Tj ET Q q 0 0 0 rg BT 149.77 234.30 Td (an ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 159.32 234.30 Td (Or) Tj ET Q q 0 0 0 rg BT 167.91 234.30 Td (encia) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 185.23 234.30 Td ( ) Tj ET Q q 0 0 0 rg BT 187.23 234.30 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 221.68 234.30 Td (on ) Tj ET Q q 0 0 0 rg BT 231.68 234.30 Td (the ) Tj ET Q q 0 0 0 rg BT 243.45 234.30 Td (market ) Tj ET Q q 0 0 0 rg BT 267.66 234.30 Td (in ) Tj ET Q q 0 0 0 rg BT 275.88 234.30 Td (the ) Tj ET Q q 0 0 0 rg BT 287.66 234.30 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 305.88 234.30 Td (EU ) Tj ET Q q 0 0 0 rg BT 318.55 234.30 Td (or ) Tj ET Q q 0 0 0 rg BT 327.21 234.30 Td (Japan.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 224.70 Td (\(d\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 224.70 Td (Sprycel) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 77.99 224.70 Td (: ) Tj ET Q q 0 0 0 rg BT 83.03 224.70 Td (In ) Tj ET Q q 0 0 0 rg BT 92.52 224.70 Td (the ) Tj ET Q q 0 0 0 rg BT 105.11 224.70 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 124.16 224.70 Td (the ) Tj ET Q q 0 0 0 rg BT 136.75 224.70 Td (COM ) Tj ET Q q 0 0 0 rg BT 157.80 224.70 Td (patent ) Tj ET Q q 0 0 0 rg BT 180.16 224.70 Td (including ) Tj ET Q q 0 0 0 rg BT 213.20 224.70 Td (PTR ) Tj ET Q q 0 0 0 rg BT 230.70 224.70 Td (expires ) Tj ET Q q 0 0 0 rg BT 256.62 224.70 Td (in ) Tj ET Q q 0 0 0 rg BT 265.66 224.70 Td (June ) Tj ET Q q 0 0 0 rg BT 283.14 224.70 Td (2020. ) Tj ET Q q 0 0 0 rg BT 303.96 224.70 Td (In ) Tj ET Q q 0 0 0 rg BT 313.45 224.70 Td (2013, ) Tj ET Q q 0 0 0 rg BT 334.27 224.70 Td (BMS ) Tj ET Q q 0 0 0 rg BT 353.99 224.70 Td (entered ) Tj ET Q q 0 0 0 rg BT 380.35 224.70 Td (into ) Tj ET Q q 0 0 0 rg BT 395.61 224.70 Td (a ) Tj ET Q q 0 0 0 rg BT 401.98 224.70 Td (settlement ) Tj ET Q q 0 0 0 rg BT 437.68 224.70 Td (agreement ) Tj ET Q q 0 0 0 rg BT 473.82 224.70 Td (with ) Tj ET Q q 0 0 0 rg BT 490.24 224.70 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 516.61 224.70 Td (regarding ) Tj ET Q q 0 0 0 rg BT 550.08 224.70 Td (a ) Tj ET Q q 0 0 0 rg BT 556.45 224.70 Td (patent ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 215.10 Td (infringement ) Tj ET Q q 0 0 0 rg BT 97.36 215.10 Td (suit ) Tj ET Q q 0 0 0 rg BT 110.96 215.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 140.98 215.10 Td (the ) Tj ET Q q 0 0 0 rg BT 152.80 215.10 Td (monohydrate ) Tj ET Q q 0 0 0 rg BT 197.05 215.10 Td (form ) Tj ET Q q 0 0 0 rg BT 214.64 215.10 Td (of ) Tj ET Q q 0 0 0 rg BT 223.34 215.10 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 254.26 215.10 Td (whereby ) Tj ET Q q 0 0 0 rg BT 283.39 215.10 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 308.98 215.10 Td (can ) Tj ET Q q 0 0 0 rg BT 322.12 215.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 345.49 215.10 Td (its ) Tj ET Q q 0 0 0 rg BT 355.08 215.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 380.66 215.10 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 411.58 215.10 Td (monohydrate ) Tj ET Q q 0 0 0 rg BT 455.83 215.10 Td (aNDA) Tj ET Q q 0 0 0 rg BT 476.28 215.10 Td ( ) Tj ET Q q 0 0 0 rg BT 478.32 215.10 Td (product ) Tj ET Q q 0 0 0 rg BT 504.79 215.10 Td (in ) Tj ET Q q 0 0 0 rg BT 513.05 215.10 Td (September ) Tj ET Q q 0 0 0 rg BT 549.30 215.10 Td (2024, ) Tj ET Q q 0 0 0 rg BT 569.34 215.10 Td (or ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 205.50 Td (earlier ) Tj ET Q q 0 0 0 rg BT 76.43 205.50 Td (in ) Tj ET Q q 0 0 0 rg BT 84.65 205.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 108.41 205.50 Td (circumstances. ) Tj ET Q q 0 0 0 rg BT 157.72 205.50 Td (In ) Tj ET Q q 0 0 0 rg BT 166.39 205.50 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 188.60 205.50 Td (the ) Tj ET Q q 0 0 0 rg BT 200.38 205.50 Td (COM ) Tj ET Q q 0 0 0 rg BT 220.60 205.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 242.15 205.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 267.25 205.50 Td (in ) Tj ET Q q 0 0 0 rg BT 275.47 205.50 Td (2021 ) Tj ET Q q 0 0 0 rg BT 293.47 205.50 Td (and ) Tj ET Q q 0 0 0 rg BT 307.02 205.50 Td (RDP) Tj ET Q q 0 0 0 rg BT 322.29 205.50 Td ( ) Tj ET Q q 0 0 0 rg BT 324.29 205.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 349.39 205.50 Td (in ) Tj ET Q q 0 0 0 rg BT 357.61 205.50 Td (2019. ) Tj ET Q q 0 0 0 rg BT 377.61 205.50 Td (For ) Tj ET Q q 0 0 0 rg BT 390.73 205.50 Td (information ) Tj ET Q q 0 0 0 rg BT 430.50 205.50 Td (on ) Tj ET Q q 0 0 0 rg BT 440.50 205.50 Td (EU ) Tj ET Q q 0 0 0 rg BT 453.16 205.50 Td (countries, ) Tj ET Q q 0 0 0 rg BT 486.48 205.50 Td (see ) Tj ET Q q 0 0 0 rg BT 498.70 205.50 Td (the ) Tj ET Q q 0 0 0 rg BT 510.47 205.50 Td (above ) Tj ET Q q 0 0 0 rg BT 531.57 205.50 Td (Footnote ) Tj ET Q q 0 0 0 rg BT 562.02 205.50 Td (^^.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 195.90 Td (\(e\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 195.90 Td (Y) Tj ET Q q 0 0 0 rg BT 57.71 195.90 Td (ervoy) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 75.48 195.90 Td (: ) Tj ET Q q 0 0 0 rg BT 79.66 195.90 Td (In ) Tj ET Q q 0 0 0 rg BT 88.29 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 100.02 195.90 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 116.21 195.90 Td (and ) Tj ET Q q 0 0 0 rg BT 129.72 195.90 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 151.90 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 163.63 195.90 Td (LOE ) Tj ET Q q 0 0 0 rg BT 181.14 195.90 Td (is ) Tj ET Q q 0 0 0 rg BT 188.44 195.90 Td (based ) Tj ET Q q 0 0 0 rg BT 208.62 195.90 Td (on ) Tj ET Q q 0 0 0 rg BT 218.58 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 230.31 195.90 Td (COM ) Tj ET Q q 0 0 0 rg BT 250.50 195.90 Td (patent ) Tj ET Q q 0 0 0 rg BT 272.01 195.90 Td (which ) Tj ET Q q 0 0 0 rg BT 293.52 195.90 Td (expires ) Tj ET Q q 0 0 0 rg BT 318.58 195.90 Td (in ) Tj ET Q q 0 0 0 rg BT 326.77 195.90 Td (2025, ) Tj ET Q q 0 0 0 rg BT 346.73 195.90 Td (including ) Tj ET Q q 0 0 0 rg BT 378.91 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 390.64 195.90 Td (granted ) Tj ET Q q 0 0 0 rg BT 416.59 195.90 Td (PTRs. ) Tj ET Q q 0 0 0 rg BT 438.34 195.90 Td (In ) Tj ET Q q 0 0 0 rg BT 446.96 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 458.70 195.90 Td (EU, ) Tj ET Q q 0 0 0 rg BT 473.32 195.90 Td (the ) Tj ET Q q 0 0 0 rg BT 485.05 195.90 Td (COM ) Tj ET Q q 0 0 0 rg BT 505.24 195.90 Td (patent ) Tj ET Q q 0 0 0 rg BT 526.75 195.90 Td (expires ) Tj ET Q q 0 0 0 rg BT 551.81 195.90 Td (in ) Tj ET Q q 0 0 0 rg BT 560.00 195.90 Td (2025 ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 186.30 Td (including ) Tj ET Q q 0 0 0 rg BT 85.94 186.30 Td (the ) Tj ET Q q 0 0 0 rg BT 97.44 186.30 Td (PTR ) Tj ET Q q 0 0 0 rg BT 113.84 186.30 Td (which ) Tj ET Q q 0 0 0 rg BT 135.11 186.30 Td (has ) Tj ET Q q 0 0 0 rg BT 147.50 186.30 Td (been ) Tj ET Q q 0 0 0 rg BT 164.33 186.30 Td (granted ) Tj ET Q q 0 0 0 rg BT 190.04 186.30 Td (in ) Tj ET Q q 0 0 0 rg BT 197.99 186.30 Td (most ) Tj ET Q q 0 0 0 rg BT 215.27 186.30 Td (countries; ) Tj ET Q q 0 0 0 rg BT 248.54 186.30 Td (however) Tj ET Q q 0 0 0 rg BT 275.77 186.30 Td (, ) Tj ET Q q 0 0 0 rg BT 279.49 186.30 Td (in ) Tj ET Q q 0 0 0 rg BT 287.44 186.30 Td (countries ) Tj ET Q q 0 0 0 rg BT 318.49 186.30 Td (in ) Tj ET Q q 0 0 0 rg BT 326.43 186.30 Td (which ) Tj ET Q q 0 0 0 rg BT 347.71 186.30 Td (the ) Tj ET Q q 0 0 0 rg BT 359.21 186.30 Td (PTR ) Tj ET Q q 0 0 0 rg BT 375.60 186.30 Td (has ) Tj ET Q q 0 0 0 rg BT 387.99 186.30 Td (not ) Tj ET Q q 0 0 0 rg BT 399.94 186.30 Td (been ) Tj ET Q q 0 0 0 rg BT 416.77 186.30 Td (granted, ) Tj ET Q q 0 0 0 rg BT 444.48 186.30 Td (the ) Tj ET Q q 0 0 0 rg BT 455.98 186.30 Td (COM ) Tj ET Q q 0 0 0 rg BT 475.93 186.30 Td (patent ) Tj ET Q q 0 0 0 rg BT 497.20 186.30 Td (will ) Tj ET Q q 0 0 0 rg BT 511.37 186.30 Td (expire ) Tj ET Q q 0 0 0 rg BT 533.08 186.30 Td (in ) Tj ET Q q 0 0 0 rg BT 541.03 186.30 Td (2020. ) Tj ET Q q 0 0 0 rg BT 560.75 186.30 Td (RDP) Tj ET Q q 0 0 0 rg BT 576.02 186.30 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 176.70 Td (expires ) Tj ET Q q 0 0 0 rg BT 79.10 176.70 Td (in ) Tj ET Q q 0 0 0 rg BT 87.32 176.70 Td (2023 ) Tj ET Q q 0 0 0 rg BT 105.32 176.70 Td (in ) Tj ET Q q 0 0 0 rg BT 113.55 176.70 Td (the ) Tj ET Q q 0 0 0 rg BT 125.32 176.70 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 141.55 176.70 Td (and ) Tj ET Q q 0 0 0 rg BT 155.10 176.70 Td (2021 ) Tj ET Q q 0 0 0 rg BT 173.10 176.70 Td (in ) Tj ET Q q 0 0 0 rg BT 181.32 176.70 Td (the ) Tj ET Q q 0 0 0 rg BT 193.09 176.70 Td (EU.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 167.10 Td (\(f\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 167.10 Td (Empliciti) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 83.33 167.10 Td (: ) Tj ET Q q 0 0 0 rg BT 87.69 167.10 Td (LOE ) Tj ET Q q 0 0 0 rg BT 105.37 167.10 Td (period ) Tj ET Q q 0 0 0 rg BT 127.94 167.10 Td (in ) Tj ET Q q 0 0 0 rg BT 136.30 167.10 Td (the ) Tj ET Q q 0 0 0 rg BT 148.21 167.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 166.57 167.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 179.37 167.10 Td (and ) Tj ET Q q 0 0 0 rg BT 193.05 167.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 213.40 167.10 Td (is ) Tj ET Q q 0 0 0 rg BT 220.88 167.10 Td (based ) Tj ET Q q 0 0 0 rg BT 241.22 167.10 Td (on ) Tj ET Q q 0 0 0 rg BT 251.36 167.10 Td (RDP) Tj ET Q q 0 0 0 rg BT 266.63 167.10 Td ( ) Tj ET Q q 0 0 0 rg BT 268.76 167.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 303.35 167.10 Td (. ) Tj ET Q q 0 0 0 rg BT 307.48 167.10 Td (PTRs ) Tj ET Q q 0 0 0 rg BT 327.40 167.10 Td (have ) Tj ET Q q 0 0 0 rg BT 344.64 167.10 Td (been ) Tj ET Q q 0 0 0 rg BT 361.87 167.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 378.67 167.10 Td (in ) Tj ET Q q 0 0 0 rg BT 387.03 167.10 Td (the ) Tj ET Q q 0 0 0 rg BT 398.93 167.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 417.29 167.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 430.09 167.10 Td (and ) Tj ET Q q 0 0 0 rg BT 443.78 167.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 464.13 167.10 Td (and ) Tj ET Q q 0 0 0 rg BT 477.81 167.10 Td (if ) Tj ET Q q 0 0 0 rg BT 484.84 167.10 Td (granted, ) Tj ET Q q 0 0 0 rg BT 512.96 167.10 Td (will ) Tj ET Q q 0 0 0 rg BT 527.54 167.10 Td (expire ) Tj ET Q q 0 0 0 rg BT 549.66 167.10 Td (in ) Tj ET Q q 0 0 0 rg BT 558.02 167.10 Td (2029. ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 157.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 72.80 157.50 Td (has ) Tj ET Q q 0 0 0 rg BT 85.37 157.50 Td (a ) Tj ET Q q 0 0 0 rg BT 90.82 157.50 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 152.25 157.50 Td (agreement ) Tj ET Q q 0 0 0 rg BT 187.47 157.50 Td (with ) Tj ET Q q 0 0 0 rg BT 203.18 157.50 Td (AbbV) Tj ET Q q 0 0 0 rg BT 222.25 157.50 Td (ie ) Tj ET Q q 0 0 0 rg BT 229.93 157.50 Td (for ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 241.16 157.50 Td (Empliciti) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 270.49 157.50 Td (. ) Tj ET Q q 0 0 0 rg BT 274.39 157.50 Td ( ) Tj ET Q q 0 0 0 rg BT 275.87 157.50 Td (AbbV) Tj ET Q q 0 0 0 rg BT 294.95 157.50 Td (ie ) Tj ET Q q 0 0 0 rg BT 302.62 157.50 Td (owns ) Tj ET Q q 0 0 0 rg BT 321.42 157.50 Td (a ) Tj ET Q q 0 0 0 rg BT 326.87 157.50 Td (COM ) Tj ET Q q 0 0 0 rg BT 347.00 157.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 368.45 157.50 Td (covering ) Tj ET Q q 0 0 0 rg BT 398.34 157.50 Td (elotuzumab ) Tj ET Q q 0 0 0 rg BT 437.57 157.50 Td (that ) Tj ET Q q 0 0 0 rg BT 451.47 157.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 476.47 157.50 Td (in ) Tj ET Q q 0 0 0 rg BT 484.60 157.50 Td (2026 ) Tj ET Q q 0 0 0 rg BT 502.50 157.50 Td (in ) Tj ET Q q 0 0 0 rg BT 510.63 157.50 Td (the ) Tj ET Q q 0 0 0 rg BT 522.30 157.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 538.43 157.50 Td (and ) Tj ET Q q 0 0 0 rg BT 551.89 157.50 Td (2024 ) Tj ET Q q 0 0 0 rg BT 569.79 157.50 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 147.90 Td (the ) Tj ET Q q 0 0 0 rg BT 66.56 147.90 Td (EU ) Tj ET Q q 0 0 0 rg BT 80.01 147.90 Td (and ) Tj ET Q q 0 0 0 rg BT 94.34 147.90 Td (Japan ) Tj ET Q q 0 0 0 rg BT 115.34 147.90 Td (\(excluding ) Tj ET Q q 0 0 0 rg BT 152.33 147.90 Td (potential ) Tj ET Q q 0 0 0 rg BT 183.11 147.90 Td (PTRs\). ) Tj ET Q q 0 0 0 rg BT 208.34 147.90 Td (For ) Tj ET Q q 0 0 0 rg BT 222.24 147.90 Td (more ) Tj ET Q q 0 0 0 rg BT 241.46 147.90 Td (information ) Tj ET Q q 0 0 0 rg BT 282.02 147.90 Td (about ) Tj ET Q q 0 0 0 rg BT 302.58 147.90 Td (our ) Tj ET Q q 0 0 0 rg BT 316.02 147.90 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 358.78 147.90 Td (with ) Tj ET Q q 0 0 0 rg BT 375.18 147.90 Td (AbbV) Tj ET Q q 0 0 0 rg BT 394.25 147.90 Td (ie, ) Tj ET Q q 0 0 0 rg BT 404.81 147.90 Td (refer ) Tj ET Q q 0 0 0 rg BT 422.69 147.90 Td (to ) Tj ET Q q 0 0 0 rg BT 431.69 147.90 Td (“—Alliances” ) Tj ET Q q 0 0 0 rg BT 479.79 147.90 Td (below ) Tj ET Q q 0 0 0 rg BT 502.13 147.90 Td (and ) Tj ET Q q 0 0 0 rg BT 516.46 147.90 Td (“Item ) Tj ET Q q 0 0 0 rg BT 537.46 147.90 Td (8. ) Tj ET Q q 0 0 0 rg BT 546.24 147.90 Td (Financial ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 138.30 Td (Statements—Note ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 114.66 138.30 Td (3) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 118.66 138.30 Td (. ) Tj ET Q q 0 0 0 rg BT 122.21 138.30 Td (Alliances.”) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 128.70 Td (\(g\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 128.70 Td (Sustiva) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 77.11 128.70 Td ( ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 79.68 128.70 Td (Franchise) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 112.12 128.70 Td (: ) Tj ET Q q 0 0 0 rg BT 116.92 128.70 Td (Exclusivity ) Tj ET Q q 0 0 0 rg BT 155.93 128.70 Td (period ) Tj ET Q q 0 0 0 rg BT 178.94 128.70 Td (relates ) Tj ET Q q 0 0 0 rg BT 202.39 128.70 Td (to ) Tj ET Q q 0 0 0 rg BT 211.19 128.70 Td (the ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 223.53 128.70 Td (Sustiva ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 249.21 128.70 Td (brand ) Tj ET Q q 0 0 0 rg BT 270.00 128.70 Td (and ) Tj ET Q q 0 0 0 rg BT 284.13 128.70 Td (does ) Tj ET Q q 0 0 0 rg BT 301.36 128.70 Td (not ) Tj ET Q q 0 0 0 rg BT 314.16 128.70 Td (include ) Tj ET Q q 0 0 0 rg BT 340.28 128.70 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 377.96 128.70 Td (related ) Tj ET Q q 0 0 0 rg BT 402.29 128.70 Td (to ) Tj ET Q q 0 0 0 rg BT 411.09 128.70 Td (any ) Tj ET Q q 0 0 0 rg BT 425.21 128.70 Td (combination ) Tj ET Q q 0 0 0 rg BT 467.78 128.70 Td (therapy) Tj ET Q q 0 0 0 rg BT 491.25 128.70 Td (. ) Tj ET Q q 0 0 0 rg BT 495.82 128.70 Td (In ) Tj ET Q q 0 0 0 rg BT 505.06 128.70 Td (the ) Tj ET Q q 0 0 0 rg BT 517.41 128.70 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 536.21 128.70 Td (the ) Tj ET Q q 0 0 0 rg BT 548.55 128.70 Td (LOE ) Tj ET Q q 0 0 0 rg BT 566.68 128.70 Td (for ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 119.10 Td (efavirenz ) Tj ET Q q 0 0 0 rg BT 85.75 119.10 Td (occurred ) Tj ET Q q 0 0 0 rg BT 115.73 119.10 Td (in ) Tj ET Q q 0 0 0 rg BT 123.96 119.10 Td (December ) Tj ET Q q 0 0 0 rg BT 158.82 119.10 Td (2017. ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 109.50 Td (\(h\) ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 54.00 109.50 Td (Reyataz) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 79.32 109.50 Td (: ) Tj ET Q q 0 0 0 rg BT 83.42 109.50 Td (In ) Tj ET Q q 0 0 0 rg BT 91.96 109.50 Td (the ) Tj ET Q q 0 0 0 rg BT 103.61 109.50 Td (EU, ) Tj ET Q q 0 0 0 rg BT 118.14 109.50 Td (the ) Tj ET Q q 0 0 0 rg BT 129.79 109.50 Td (market ) Tj ET Q q 0 0 0 rg BT 153.88 109.50 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 190.86 109.50 Td (is ) Tj ET Q q 0 0 0 rg BT 198.07 109.50 Td (projected ) Tj ET Q q 0 0 0 rg BT 229.70 109.50 Td (to ) Tj ET Q q 0 0 0 rg BT 237.80 109.50 Td (expire ) Tj ET Q q 0 0 0 rg BT 259.66 109.50 Td (between ) Tj ET Q q 0 0 0 rg BT 288.19 109.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 306.06 109.50 Td (and ) Tj ET Q q 0 0 0 rg BT 319.49 109.50 Td (2019. ) Tj ET Q q 0 0 0 rg BT 339.23 109.50 Td (The ) Tj ET Q q 0 0 0 rg BT 353.54 109.50 Td (COM ) Tj ET Q q 0 0 0 rg BT 373.64 109.50 Td (patent ) Tj ET Q q 0 0 0 rg BT 395.06 109.50 Td (including ) Tj ET Q q 0 0 0 rg BT 427.15 109.50 Td (PTR ) Tj ET Q q 0 0 0 rg BT 443.70 109.50 Td (expired ) Tj ET Q q 0 0 0 rg BT 469.56 109.50 Td (in ) Tj ET Q q 0 0 0 rg BT 477.66 109.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 495.53 109.50 Td (in ) Tj ET Q q 0 0 0 rg BT 503.63 109.50 Td (the ) Tj ET Q q 0 0 0 rg BT 515.27 109.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 531.37 109.50 Td (and ) Tj ET Q q 0 0 0 rg BT 544.80 109.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 569.77 109.50 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 99.90 Td (2019 ) Tj ET Q q 0 0 0 rg BT 72.00 99.90 Td (in ) Tj ET Q q 0 0 0 rg BT 80.22 99.90 Td (the ) Tj ET Q q 0 0 0 rg BT 92.00 99.90 Td (EU.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 90.30 Td (\(i\) ) Tj ET Q q 0 0 0 rg BT 54.00 90.30 Td (Hepatitis ) Tj ET Q q 0 0 0 rg BT 85.35 90.30 Td (C ) Tj ET Q q 0 0 0 rg BT 93.16 90.30 Td (Franchise: ) Tj ET Q q 0 0 0 rg BT 128.95 90.30 Td (Relates ) Tj ET Q q 0 0 0 rg BT 154.96 90.30 Td (to ) Tj ET Q q 0 0 0 rg BT 163.66 90.30 Td (products ) Tj ET Q q 0 0 0 rg BT 193.68 90.30 Td (including ) Tj ET Q q 0 0 0 rg BT 226.36 90.30 Td (daclatasvir) Tj ET Q q 0 0 0 rg BT 260.69 90.30 Td (, ) Tj ET Q q 0 0 0 rg BT 265.16 90.30 Td (such ) Tj ET Q q 0 0 0 rg BT 282.29 90.30 Td (as ) Tj ET Q q 0 0 0 rg BT 291.43 90.30 Td (the ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 303.67 90.30 Td (Daklinza) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 332.55 90.30 Td ( ) Tj ET Q q 0 0 0 rg BT 335.02 90.30 Td (brand. ) Tj ET Q q 0 0 0 rg BT 357.71 90.30 Td (In ) Tj ET Q q 0 0 0 rg BT 366.84 90.30 Td (the ) Tj ET Q q 0 0 0 rg BT 379.08 90.30 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 397.78 90.30 Td (the ) Tj ET Q q 0 0 0 rg BT 410.02 90.30 Td (LOE ) Tj ET Q q 0 0 0 rg BT 428.04 90.30 Td (is ) Tj ET Q q 0 0 0 rg BT 435.84 90.30 Td (based ) Tj ET Q q 0 0 0 rg BT 456.53 90.30 Td (on ) Tj ET Q q 0 0 0 rg BT 467.00 90.30 Td (the ) Tj ET Q q 0 0 0 rg BT 479.24 90.30 Td (COM ) Tj ET Q q 0 0 0 rg BT 499.93 90.30 Td (patent ) Tj ET Q q 0 0 0 rg BT 521.95 90.30 Td (expiry ) Tj ET Q q 0 0 0 rg BT 544.86 90.30 Td (and ) Tj ET Q q 0 0 0 rg BT 558.88 90.30 Td (if ) Tj ET Q q 0 0 0 rg BT 566.23 90.30 Td (the ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 80.70 Td (pending ) Tj ET Q q 0 0 0 rg BT 81.51 80.70 Td (PTR ) Tj ET Q q 0 0 0 rg BT 97.93 80.70 Td (is ) Tj ET Q q 0 0 0 rg BT 105.00 80.70 Td (granted, ) Tj ET Q q 0 0 0 rg BT 132.73 80.70 Td (the ) Tj ET Q q 0 0 0 rg BT 144.24 80.70 Td (expiry ) Tj ET Q q 0 0 0 rg BT 166.42 80.70 Td (will ) Tj ET Q q 0 0 0 rg BT 180.61 80.70 Td (be ) Tj ET Q q 0 0 0 rg BT 189.90 80.70 Td (2029. ) Tj ET Q q 0 0 0 rg BT 209.64 80.70 Td (In ) Tj ET Q q 0 0 0 rg BT 218.04 80.70 Td (Europe, ) Tj ET Q q 0 0 0 rg BT 244.88 80.70 Td (the ) Tj ET Q q 0 0 0 rg BT 256.40 80.70 Td (LOE ) Tj ET Q q 0 0 0 rg BT 273.69 80.70 Td (is ) Tj ET Q q 0 0 0 rg BT 280.77 80.70 Td (based ) Tj ET Q q 0 0 0 rg BT 300.72 80.70 Td (on ) Tj ET Q q 0 0 0 rg BT 310.46 80.70 Td (the ) Tj ET Q q 0 0 0 rg BT 321.97 80.70 Td (COM ) Tj ET Q q 0 0 0 rg BT 341.94 80.70 Td (patent ) Tj ET Q q 0 0 0 rg BT 363.23 80.70 Td (expiry ) Tj ET Q q 0 0 0 rg BT 385.41 80.70 Td (in ) Tj ET Q q 0 0 0 rg BT 393.37 80.70 Td (2027, ) Tj ET Q q 0 0 0 rg BT 413.11 80.70 Td (however) Tj ET Q q 0 0 0 rg BT 440.33 80.70 Td (, ) Tj ET Q q 0 0 0 rg BT 444.07 80.70 Td (the ) Tj ET Q q 0 0 0 rg BT 455.59 80.70 Td (PTR, ) Tj ET Q q 0 0 0 rg BT 474.00 80.70 Td (which ) Tj ET Q q 0 0 0 rg BT 495.29 80.70 Td (has ) Tj ET Q q 0 0 0 rg BT 507.69 80.70 Td (been ) Tj ET Q q 0 0 0 rg BT 524.54 80.70 Td (granted ) Tj ET Q q 0 0 0 rg BT 550.26 80.70 Td (in ) Tj ET Q q 0 0 0 rg BT 558.23 80.70 Td (many ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 71.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 87.32 71.10 Td (will ) Tj ET Q q 0 0 0 rg BT 101.77 71.10 Td (expire ) Tj ET Q q 0 0 0 rg BT 123.76 71.10 Td (in ) Tj ET Q q 0 0 0 rg BT 131.98 71.10 Td (2029. ) Tj ET Q q 0 0 0 rg BT 151.98 71.10 Td ( ) Tj ET Q q 0 0 0 rg BT 153.98 71.10 Td (In ) Tj ET Q q 0 0 0 rg BT 162.64 71.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 184.86 71.10 Td (the ) Tj ET Q q 0 0 0 rg BT 196.63 71.10 Td (COM ) Tj ET Q q 0 0 0 rg BT 216.86 71.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 238.41 71.10 Td (expires ) Tj ET Q q 0 0 0 rg BT 263.51 71.10 Td (in ) Tj ET Q q 0 0 0 rg BT 271.73 71.10 Td (2028 ) Tj ET Q q 0 0 0 rg BT 289.73 71.10 Td (including ) Tj ET Q q 0 0 0 rg BT 321.95 71.10 Td (the ) Tj ET Q q 0 0 0 rg BT 333.72 71.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 359.71 71.10 Td (PTR.) Tj ET Q endstream endobj 17 0 obj <> endobj 18 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (8) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Resear) Tj ET Q q 0 0 0 rg BT 65.25 749.25 Td (ch and Development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 727.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 59.95 727.65 Td (is ) Tj ET Q q 0 0 0 rg BT 68.89 727.65 Td (critical ) Tj ET Q q 0 0 0 rg BT 98.93 727.65 Td (to ) Tj ET Q q 0 0 0 rg BT 108.98 727.65 Td (our ) Tj ET Q q 0 0 0 rg BT 124.59 727.65 Td (long-term ) Tj ET Q q 0 0 0 rg BT 166.30 727.65 Td (competitiveness. ) Tj ET Q q 0 0 0 rg BT 235.34 727.65 Td (W) Tj ET Q q 0 0 0 rg BT 243.98 727.65 Td (e ) Tj ET Q q 0 0 0 rg BT 250.70 727.65 Td (concentrate ) Tj ET Q q 0 0 0 rg BT 299.05 727.65 Td (our ) Tj ET Q q 0 0 0 rg BT 314.66 727.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 338.61 727.65 Td (ef) Tj ET Q q 0 0 0 rg BT 346.19 727.65 Td (forts ) Tj ET Q q 0 0 0 rg BT 366.80 727.65 Td (in ) Tj ET Q q 0 0 0 rg BT 376.86 727.65 Td (the ) Tj ET Q q 0 0 0 rg BT 391.35 727.65 Td (following ) Tj ET Q q 0 0 0 rg BT 432.51 727.65 Td (disease ) Tj ET Q q 0 0 0 rg BT 463.67 727.65 Td (areas ) Tj ET Q q 0 0 0 rg BT 486.48 727.65 Td (with ) Tj ET Q q 0 0 0 rg BT 506.54 727.65 Td (significant ) Tj ET Q q 0 0 0 rg BT 551.02 727.65 Td (unmet ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 715.65 Td (medical ) Tj ET Q q 0 0 0 rg BT 69.54 715.65 Td (needs: ) Tj ET Q q 0 0 0 rg BT 96.97 715.65 Td (oncology) Tj ET Q q 0 0 0 rg BT 133.54 715.65 Td (, ) Tj ET Q q 0 0 0 rg BT 137.93 715.65 Td (including ) Tj ET Q q 0 0 0 rg BT 177.59 715.65 Td (IO, ) Tj ET Q q 0 0 0 rg BT 192.53 715.65 Td (immunoscience ) Tj ET Q q 0 0 0 rg BT 257.18 715.65 Td (with ) Tj ET Q q 0 0 0 rg BT 276.85 715.65 Td (priorities ) Tj ET Q q 0 0 0 rg BT 314.84 715.65 Td (in ) Tj ET Q q 0 0 0 rg BT 324.51 715.65 Td (lupus, ) Tj ET Q q 0 0 0 rg BT 350.57 715.65 Td (RA) Tj ET Q q 0 0 0 rg BT 363.91 715.65 Td ( ) Tj ET Q q 0 0 0 rg BT 365.79 715.65 Td (and ) Tj ET Q q 0 0 0 rg BT 382.12 715.65 Td (inflammatory ) Tj ET Q q 0 0 0 rg BT 438.44 715.65 Td (bowel ) Tj ET Q q 0 0 0 rg BT 464.77 715.65 Td (disease, ) Tj ET Q q 0 0 0 rg BT 498.03 715.65 Td (cardiovascular ) Tj ET Q q 0 0 0 rg BT 558.22 715.65 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 703.65 Td (priority ) Tj ET Q q 0 0 0 rg BT 67.57 703.65 Td (in ) Tj ET Q q 0 0 0 rg BT 76.93 703.65 Td (heart ) Tj ET Q q 0 0 0 rg BT 98.49 703.65 Td (disease ) Tj ET Q q 0 0 0 rg BT 128.94 703.65 Td (and ) Tj ET Q q 0 0 0 rg BT 144.96 703.65 Td (fibrotic ) Tj ET Q q 0 0 0 rg BT 175.97 703.65 Td (disease ) Tj ET Q q 0 0 0 rg BT 206.42 703.65 Td (with ) Tj ET Q q 0 0 0 rg BT 225.78 703.65 Td (priorities ) Tj ET Q q 0 0 0 rg BT 263.46 703.65 Td (in ) Tj ET Q q 0 0 0 rg BT 272.82 703.65 Td (lung ) Tj ET Q q 0 0 0 rg BT 292.17 703.65 Td (\(IPF\) ) Tj ET Q q 0 0 0 rg BT 314.86 703.65 Td (and ) Tj ET Q q 0 0 0 rg BT 330.88 703.65 Td (liver ) Tj ET Q q 0 0 0 rg BT 350.78 703.65 Td (\(NASH\). ) Tj ET Q q 0 0 0 rg BT 388.63 703.65 Td (W) Tj ET Q q 0 0 0 rg BT 397.27 703.65 Td (e ) Tj ET Q q 0 0 0 rg BT 403.28 703.65 Td (also ) Tj ET Q q 0 0 0 rg BT 420.97 703.65 Td (continue ) Tj ET Q q 0 0 0 rg BT 456.98 703.65 Td (to ) Tj ET Q q 0 0 0 rg BT 466.34 703.65 Td (analyze ) Tj ET Q q 0 0 0 rg BT 498.44 703.65 Td (and ) Tj ET Q q 0 0 0 rg BT 514.46 703.65 Td (may ) Tj ET Q q 0 0 0 rg BT 533.25 703.65 Td (selectively ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 691.65 Td (pursue ) Tj ET Q q 0 0 0 rg BT 64.94 691.65 Td (promising ) Tj ET Q q 0 0 0 rg BT 107.78 691.65 Td (leads ) Tj ET Q q 0 0 0 rg BT 130.61 691.65 Td (in ) Tj ET Q q 0 0 0 rg BT 140.67 691.65 Td (other ) Tj ET Q q 0 0 0 rg BT 163.50 691.65 Td (areas. ) Tj ET Q q 0 0 0 rg BT 188.82 691.65 Td (In ) Tj ET Q q 0 0 0 rg BT 199.44 691.65 Td (addition ) Tj ET Q q 0 0 0 rg BT 234.49 691.65 Td (to ) Tj ET Q q 0 0 0 rg BT 244.55 691.65 Td (discovering ) Tj ET Q q 0 0 0 rg BT 293.49 691.65 Td (and ) Tj ET Q q 0 0 0 rg BT 310.21 691.65 Td (developing ) Tj ET Q q 0 0 0 rg BT 356.93 691.65 Td (new ) Tj ET Q q 0 0 0 rg BT 375.87 691.65 Td (molecular ) Tj ET Q q 0 0 0 rg BT 418.13 691.65 Td (entities, ) Tj ET Q q 0 0 0 rg BT 451.80 691.65 Td (we ) Tj ET Q q 0 0 0 rg BT 465.74 691.65 Td (look ) Tj ET Q q 0 0 0 rg BT 485.80 691.65 Td (for ) Tj ET Q q 0 0 0 rg BT 499.75 691.65 Td (ways ) Tj ET Q q 0 0 0 rg BT 522.58 691.65 Td (to ) Tj ET Q q 0 0 0 rg BT 532.64 691.65 Td (expand ) Tj ET Q q 0 0 0 rg BT 563.80 691.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 679.65 Td (value ) Tj ET Q q 0 0 0 rg BT 60.16 679.65 Td (of ) Tj ET Q q 0 0 0 rg BT 70.99 679.65 Td (existing ) Tj ET Q q 0 0 0 rg BT 105.15 679.65 Td (products ) Tj ET Q q 0 0 0 rg BT 142.09 679.65 Td (through ) Tj ET Q q 0 0 0 rg BT 175.70 679.65 Td (new ) Tj ET Q q 0 0 0 rg BT 194.86 679.65 Td (indications ) Tj ET Q q 0 0 0 rg BT 241.24 679.65 Td (and ) Tj ET Q q 0 0 0 rg BT 258.18 679.65 Td (formulations ) Tj ET Q q 0 0 0 rg BT 311.78 679.65 Td (that ) Tj ET Q q 0 0 0 rg BT 329.28 679.65 Td (can ) Tj ET Q q 0 0 0 rg BT 345.65 679.65 Td (provide ) Tj ET Q q 0 0 0 rg BT 378.70 679.65 Td (additional ) Tj ET Q q 0 0 0 rg BT 421.19 679.65 Td (benefits ) Tj ET Q q 0 0 0 rg BT 455.35 679.65 Td (to ) Tj ET Q q 0 0 0 rg BT 465.62 679.65 Td (patients.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 658.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.56 658.05 Td (order ) Tj ET Q q 0 0 0 rg BT 69.89 658.05 Td (for ) Tj ET Q q 0 0 0 rg BT 83.78 658.05 Td (a ) Tj ET Q q 0 0 0 rg BT 90.45 658.05 Td (new ) Tj ET Q q 0 0 0 rg BT 109.34 658.05 Td (drug ) Tj ET Q q 0 0 0 rg BT 129.90 658.05 Td (to ) Tj ET Q q 0 0 0 rg BT 139.91 658.05 Td (reach ) Tj ET Q q 0 0 0 rg BT 163.79 658.05 Td (the ) Tj ET Q q 0 0 0 rg BT 178.23 658.05 Td (market, ) Tj ET Q q 0 0 0 rg BT 210.73 658.05 Td (industry ) Tj ET Q q 0 0 0 rg BT 245.74 658.05 Td (practice ) Tj ET Q q 0 0 0 rg BT 279.61 658.05 Td (and ) Tj ET Q q 0 0 0 rg BT 296.28 658.05 Td (government ) Tj ET Q q 0 0 0 rg BT 346.27 658.05 Td (regulations ) Tj ET Q q 0 0 0 rg BT 392.93 658.05 Td (in ) Tj ET Q q 0 0 0 rg BT 402.94 658.05 Td (the ) Tj ET Q q 0 0 0 rg BT 417.39 658.05 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 439.90 658.05 Td (the ) Tj ET Q q 0 0 0 rg BT 454.35 658.05 Td (EU ) Tj ET Q q 0 0 0 rg BT 469.91 658.05 Td (and ) Tj ET Q q 0 0 0 rg BT 486.58 658.05 Td (most ) Tj ET Q q 0 0 0 rg BT 508.26 658.05 Td (foreign ) Tj ET Q q 0 0 0 rg BT 539.37 658.05 Td (countries ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 646.05 Td (provide ) Tj ET Q q 0 0 0 rg BT 68.63 646.05 Td (for ) Tj ET Q q 0 0 0 rg BT 82.37 646.05 Td (the ) Tj ET Q q 0 0 0 rg BT 96.67 646.05 Td (determination ) Tj ET Q q 0 0 0 rg BT 154.29 646.05 Td (of ) Tj ET Q q 0 0 0 rg BT 164.70 646.05 Td (a ) Tj ET Q q 0 0 0 rg BT 171.22 646.05 Td (drug’) Tj ET Q q 0 0 0 rg BT 192.33 646.05 Td (s ) Tj ET Q q 0 0 0 rg BT 198.31 646.05 Td (ef) Tj ET Q q 0 0 0 rg BT 205.90 646.05 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 252.40 646.05 Td (and ) Tj ET Q q 0 0 0 rg BT 268.92 646.05 Td (safety ) Tj ET Q q 0 0 0 rg BT 294.88 646.05 Td (through ) Tj ET Q q 0 0 0 rg BT 328.07 646.05 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 372.35 646.05 Td (tests ) Tj ET Q q 0 0 0 rg BT 392.21 646.05 Td (and ) Tj ET Q q 0 0 0 rg BT 408.73 646.05 Td (controlled ) Tj ET Q q 0 0 0 rg BT 451.36 646.05 Td (clinical ) Tj ET Q q 0 0 0 rg BT 482.87 646.05 Td (evaluation. ) Tj ET Q q 0 0 0 rg BT 528.95 646.05 Td (The ) Tj ET Q q 0 0 0 rg BT 546.58 646.05 Td (clinical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 634.05 Td (development ) Tj ET Q q 0 0 0 rg BT 89.50 634.05 Td (of ) Tj ET Q q 0 0 0 rg BT 99.67 634.05 Td (a ) Tj ET Q q 0 0 0 rg BT 105.96 634.05 Td (potential ) Tj ET Q q 0 0 0 rg BT 142.80 634.05 Td (new ) Tj ET Q q 0 0 0 rg BT 161.31 634.05 Td (drug ) Tj ET Q q 0 0 0 rg BT 181.48 634.05 Td (typically ) Tj ET Q q 0 0 0 rg BT 218.32 634.05 Td (includes ) Tj ET Q q 0 0 0 rg BT 253.49 634.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 278.67 634.05 Td (I, ) Tj ET Q q 0 0 0 rg BT 286.35 634.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 311.52 634.05 Td (II ) Tj ET Q q 0 0 0 rg BT 320.03 634.05 Td (and ) Tj ET Q q 0 0 0 rg BT 336.32 634.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 361.49 634.05 Td (III ) Tj ET Q q 0 0 0 rg BT 373.33 634.05 Td (clinical ) Tj ET Q q 0 0 0 rg BT 404.61 634.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 434.23 634.05 Td (that ) Tj ET Q q 0 0 0 rg BT 451.08 634.05 Td (have ) Tj ET Q q 0 0 0 rg BT 471.80 634.05 Td (been ) Tj ET Q q 0 0 0 rg BT 492.52 634.05 Td (designed ) Tj ET Q q 0 0 0 rg BT 529.92 634.05 Td (specifically ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 622.05 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 622.05 Td (support ) Tj ET Q q 0 0 0 rg BT 78.78 622.05 Td (a ) Tj ET Q q 0 0 0 rg BT 85.72 622.05 Td (new ) Tj ET Q q 0 0 0 rg BT 104.88 622.05 Td (drug ) Tj ET Q q 0 0 0 rg BT 125.71 622.05 Td (application ) Tj ET Q q 0 0 0 rg BT 172.64 622.05 Td (for ) Tj ET Q q 0 0 0 rg BT 186.80 622.05 Td (a ) Tj ET Q q 0 0 0 rg BT 193.73 622.05 Td (particular ) Tj ET Q q 0 0 0 rg BT 234.54 622.05 Td (indication, ) Tj ET Q q 0 0 0 rg BT 279.54 622.05 Td (assuming ) Tj ET Q q 0 0 0 rg BT 319.81 622.05 Td (the ) Tj ET Q q 0 0 0 rg BT 334.53 622.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 364.81 622.05 Td (are ) Tj ET Q q 0 0 0 rg BT 379.52 622.05 Td (successful.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 600.45 Td (Phase ) Tj ET Q q 0 0 0 rg BT 62.20 600.45 Td (I ) Tj ET Q q 0 0 0 rg BT 68.41 600.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 100.71 600.45 Td (studies ) Tj ET Q q 0 0 0 rg BT 131.36 600.45 Td (involve ) Tj ET Q q 0 0 0 rg BT 164.23 600.45 Td (a ) Tj ET Q q 0 0 0 rg BT 171.54 600.45 Td (small ) Tj ET Q q 0 0 0 rg BT 196.08 600.45 Td (number ) Tj ET Q q 0 0 0 rg BT 229.50 600.45 Td (of ) Tj ET Q q 0 0 0 rg BT 240.70 600.45 Td (healthy ) Tj ET Q q 0 0 0 rg BT 273.01 600.45 Td (volunteers ) Tj ET Q q 0 0 0 rg BT 317.54 600.45 Td (or ) Tj ET Q q 0 0 0 rg BT 328.74 600.45 Td (patients ) Tj ET Q q 0 0 0 rg BT 362.72 600.45 Td (suf) Tj ET Q q 0 0 0 rg BT 374.76 600.45 Td (fering ) Tj ET Q q 0 0 0 rg BT 401.51 600.45 Td (from ) Tj ET Q q 0 0 0 rg BT 423.82 600.45 Td (the ) Tj ET Q q 0 0 0 rg BT 438.92 600.45 Td (indicated ) Tj ET Q q 0 0 0 rg BT 478.44 600.45 Td (disease ) Tj ET Q q 0 0 0 rg BT 510.19 600.45 Td (to ) Tj ET Q q 0 0 0 rg BT 520.84 600.45 Td (test ) Tj ET Q q 0 0 0 rg BT 537.60 600.45 Td (for ) Tj ET Q q 0 0 0 rg BT 552.14 600.45 Td (safety ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 588.45 Td (and ) Tj ET Q q 0 0 0 rg BT 53.22 588.45 Td (proper ) Tj ET Q q 0 0 0 rg BT 82.09 588.45 Td (dosing. ) Tj ET Q q 0 0 0 rg BT 114.04 588.45 Td (Phase ) Tj ET Q q 0 0 0 rg BT 140.15 588.45 Td (II ) Tj ET Q q 0 0 0 rg BT 149.58 588.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 181.79 588.45 Td (studies ) Tj ET Q q 0 0 0 rg BT 212.35 588.45 Td (involve ) Tj ET Q q 0 0 0 rg BT 245.12 588.45 Td (a ) Tj ET Q q 0 0 0 rg BT 252.33 588.45 Td (lar) Tj ET Q q 0 0 0 rg BT 262.70 588.45 Td (ger ) Tj ET Q q 0 0 0 rg BT 278.25 588.45 Td (patient ) Tj ET Q q 0 0 0 rg BT 308.24 588.45 Td (population ) Tj ET Q q 0 0 0 rg BT 353.79 588.45 Td (to ) Tj ET Q q 0 0 0 rg BT 364.34 588.45 Td (investigate ) Tj ET Q q 0 0 0 rg BT 410.44 588.45 Td (side ) Tj ET Q q 0 0 0 rg BT 429.33 588.45 Td (ef) Tj ET Q q 0 0 0 rg BT 436.91 588.45 Td (fects, ) Tj ET Q q 0 0 0 rg BT 461.07 588.45 Td (ef) Tj ET Q q 0 0 0 rg BT 468.66 588.45 Td (ficacy) Tj ET Q q 0 0 0 rg BT 492.43 588.45 Td (, ) Tj ET Q q 0 0 0 rg BT 497.71 588.45 Td (and ) Tj ET Q q 0 0 0 rg BT 514.92 588.45 Td (optimal ) Tj ET Q q 0 0 0 rg BT 548.25 588.45 Td (dosage ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 576.45 Td (of ) Tj ET Q q 0 0 0 rg BT 46.61 576.45 Td (the ) Tj ET Q q 0 0 0 rg BT 61.11 576.45 Td (drug ) Tj ET Q q 0 0 0 rg BT 81.71 576.45 Td (candidate. ) Tj ET Q q 0 0 0 rg BT 124.80 576.45 Td (Phase ) Tj ET Q q 0 0 0 rg BT 150.41 576.45 Td (III ) Tj ET Q q 0 0 0 rg BT 162.68 576.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 194.39 576.45 Td (studies ) Tj ET Q q 0 0 0 rg BT 224.45 576.45 Td (are ) Tj ET Q q 0 0 0 rg BT 238.94 576.45 Td (conducted ) Tj ET Q q 0 0 0 rg BT 282.31 576.45 Td (to ) Tj ET Q q 0 0 0 rg BT 292.37 576.45 Td (confirm ) Tj ET Q q 0 0 0 rg BT 326.30 576.45 Td (Phase ) Tj ET Q q 0 0 0 rg BT 351.91 576.45 Td (II ) Tj ET Q q 0 0 0 rg BT 360.85 576.45 Td (results ) Tj ET Q q 0 0 0 rg BT 389.24 576.45 Td (in ) Tj ET Q q 0 0 0 rg BT 399.29 576.45 Td (a ) Tj ET Q q 0 0 0 rg BT 406.01 576.45 Td (significantly ) Tj ET Q q 0 0 0 rg BT 458.28 576.45 Td (lar) Tj ET Q q 0 0 0 rg BT 468.65 576.45 Td (ger ) Tj ET Q q 0 0 0 rg BT 483.70 576.45 Td (patient ) Tj ET Q q 0 0 0 rg BT 513.19 576.45 Td (population ) Tj ET Q q 0 0 0 rg BT 558.24 576.45 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 564.45 Td (a ) Tj ET Q q 0 0 0 rg BT 43.65 564.45 Td (longer ) Tj ET Q q 0 0 0 rg BT 72.40 564.45 Td (term ) Tj ET Q q 0 0 0 rg BT 93.93 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 111.58 564.45 Td (to ) Tj ET Q q 0 0 0 rg BT 122.57 564.45 Td (provide ) Tj ET Q q 0 0 0 rg BT 156.32 564.45 Td (reliable ) Tj ET Q q 0 0 0 rg BT 189.51 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 207.16 564.45 Td (conclusive ) Tj ET Q q 0 0 0 rg BT 253.13 564.45 Td (data ) Tj ET Q q 0 0 0 rg BT 272.99 564.45 Td (regarding ) Tj ET Q q 0 0 0 rg BT 314.52 564.45 Td (the ) Tj ET Q q 0 0 0 rg BT 329.94 564.45 Td (safety ) Tj ET Q q 0 0 0 rg BT 357.03 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 374.67 564.45 Td (ef) Tj ET Q q 0 0 0 rg BT 382.26 564.45 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 409.89 564.45 Td (of ) Tj ET Q q 0 0 0 rg BT 421.43 564.45 Td (a ) Tj ET Q q 0 0 0 rg BT 429.08 564.45 Td (drug ) Tj ET Q q 0 0 0 rg BT 450.61 564.45 Td (candidate. ) Tj ET Q q 0 0 0 rg BT 493.92 564.45 Td (Although ) Tj ET Q q 0 0 0 rg BT 534.91 564.45 Td (regulatory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 552.45 Td (approval ) Tj ET Q q 0 0 0 rg BT 73.52 552.45 Td (is ) Tj ET Q q 0 0 0 rg BT 82.72 552.45 Td (typically ) Tj ET Q q 0 0 0 rg BT 120.25 552.45 Td (based ) Tj ET Q q 0 0 0 rg BT 145.55 552.45 Td (on ) Tj ET Q q 0 0 0 rg BT 158.08 552.45 Td (the ) Tj ET Q q 0 0 0 rg BT 172.83 552.45 Td (results ) Tj ET Q q 0 0 0 rg BT 201.47 552.45 Td (of ) Tj ET Q q 0 0 0 rg BT 212.33 552.45 Td (Phase ) Tj ET Q q 0 0 0 rg BT 238.20 552.45 Td (III ) Tj ET Q q 0 0 0 rg BT 250.72 552.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 282.68 552.45 Td (studies, ) Tj ET Q q 0 0 0 rg BT 315.50 552.45 Td (there ) Tj ET Q q 0 0 0 rg BT 338.01 552.45 Td (are ) Tj ET Q q 0 0 0 rg BT 352.75 552.45 Td (times ) Tj ET Q q 0 0 0 rg BT 376.95 552.45 Td (when ) Tj ET Q q 0 0 0 rg BT 401.15 552.45 Td (approval ) Tj ET Q q 0 0 0 rg BT 438.66 552.45 Td (can ) Tj ET Q q 0 0 0 rg BT 455.07 552.45 Td (be ) Tj ET Q q 0 0 0 rg BT 467.05 552.45 Td (granted ) Tj ET Q q 0 0 0 rg BT 499.56 552.45 Td (based ) Tj ET Q q 0 0 0 rg BT 524.87 552.45 Td (on ) Tj ET Q q 0 0 0 rg BT 537.40 552.45 Td (data ) Tj ET Q q 0 0 0 rg BT 556.59 552.45 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 540.45 Td (earlier ) Tj ET Q q 0 0 0 rg BT 64.03 540.45 Td (studies.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 518.85 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 518.85 Td (e ) Tj ET Q q 0 0 0 rg BT 51.05 518.85 Td (consider ) Tj ET Q q 0 0 0 rg BT 86.90 518.85 Td (our ) Tj ET Q q 0 0 0 rg BT 102.21 518.85 Td (registrational ) Tj ET Q q 0 0 0 rg BT 156.94 518.85 Td (studies ) Tj ET Q q 0 0 0 rg BT 186.70 518.85 Td (to ) Tj ET Q q 0 0 0 rg BT 196.45 518.85 Td (be ) Tj ET Q q 0 0 0 rg BT 207.86 518.85 Td (our ) Tj ET Q q 0 0 0 rg BT 223.17 518.85 Td (significant ) Tj ET Q q 0 0 0 rg BT 267.35 518.85 Td (R&D ) Tj ET Q q 0 0 0 rg BT 291.00 518.85 Td (programs. ) Tj ET Q q 0 0 0 rg BT 333.10 518.85 Td (These ) Tj ET Q q 0 0 0 rg BT 358.95 518.85 Td (programs ) Tj ET Q q 0 0 0 rg BT 398.70 518.85 Td (may ) Tj ET Q q 0 0 0 rg BT 417.89 518.85 Td (include ) Tj ET Q q 0 0 0 rg BT 449.30 518.85 Td (both ) Tj ET Q q 0 0 0 rg BT 469.05 518.85 Td (investigational ) Tj ET Q q 0 0 0 rg BT 529.90 518.85 Td (compounds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 506.85 Td (in ) Tj ET Q q 0 0 0 rg BT 47.30 506.85 Td (Phases ) Tj ET Q q 0 0 0 rg BT 78.03 506.85 Td (II ) Tj ET Q q 0 0 0 rg BT 88.21 506.85 Td (and ) Tj ET Q q 0 0 0 rg BT 106.17 506.85 Td (III ) Tj ET Q q 0 0 0 rg BT 119.67 506.85 Td (development ) Tj ET Q q 0 0 0 rg BT 174.84 506.85 Td (for ) Tj ET Q q 0 0 0 rg BT 190.02 506.85 Td (initial ) Tj ET Q q 0 0 0 rg BT 216.87 506.85 Td (indications ) Tj ET Q q 0 0 0 rg BT 264.27 506.85 Td (and ) Tj ET Q q 0 0 0 rg BT 282.22 506.85 Td (marketed ) Tj ET Q q 0 0 0 rg BT 322.94 506.85 Td (products ) Tj ET Q q 0 0 0 rg BT 360.90 506.85 Td (that ) Tj ET Q q 0 0 0 rg BT 379.41 506.85 Td (are ) Tj ET Q q 0 0 0 rg BT 395.13 506.85 Td (in ) Tj ET Q q 0 0 0 rg BT 406.43 506.85 Td (development ) Tj ET Q q 0 0 0 rg BT 461.59 506.85 Td (for ) Tj ET Q q 0 0 0 rg BT 476.77 506.85 Td (additional ) Tj ET Q q 0 0 0 rg BT 520.28 506.85 Td (indications ) Tj ET Q q 0 0 0 rg BT 567.68 506.85 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 494.85 Td (formulations. ) Tj ET Q q 0 0 0 rg BT 91.92 494.85 Td (Expanding ) Tj ET Q q 0 0 0 rg BT 137.56 494.85 Td (our ) Tj ET Q q 0 0 0 rg BT 153.21 494.85 Td (currently ) Tj ET Q q 0 0 0 rg BT 191.62 494.85 Td (marketed ) Tj ET Q q 0 0 0 rg BT 231.14 494.85 Td (products, ) Tj ET Q q 0 0 0 rg BT 270.39 494.85 Td (particularly ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 318.80 494.85 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 348.24 494.85 Td ( ) Tj ET Q q 0 0 0 rg BT 350.56 494.85 Td (in ) Tj ET Q q 0 0 0 rg BT 360.65 494.85 Td (combination ) Tj ET Q q 0 0 0 rg BT 412.96 494.85 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 433.05 494.85 Td (Y) Tj ET Q q 0 0 0 rg BT 437.70 494.85 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.90 494.85 Td ( ) Tj ET Q q 0 0 0 rg BT 462.22 494.85 Td (and ) Tj ET Q q 0 0 0 rg BT 478.98 494.85 Td (other ) Tj ET Q q 0 0 0 rg BT 501.84 494.85 Td (agents ) Tj ET Q q 0 0 0 rg BT 529.70 494.85 Td (in ) Tj ET Q q 0 0 0 rg BT 539.80 494.85 Td (both ) Tj ET Q q 0 0 0 rg BT 559.89 494.85 Td (first ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 482.85 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 482.85 Td (second-line ) Tj ET Q q 0 0 0 rg BT 101.53 482.85 Td (therapy ) Tj ET Q q 0 0 0 rg BT 134.02 482.85 Td (with ) Tj ET Q q 0 0 0 rg BT 154.30 482.85 Td (new ) Tj ET Q q 0 0 0 rg BT 173.46 482.85 Td (indications, ) Tj ET Q q 0 0 0 rg BT 222.34 482.85 Td (is ) Tj ET Q q 0 0 0 rg BT 231.51 482.85 Td (a ) Tj ET Q q 0 0 0 rg BT 238.45 482.85 Td (substantial ) Tj ET Q q 0 0 0 rg BT 283.72 482.85 Td (portion ) Tj ET Q q 0 0 0 rg BT 315.11 482.85 Td (of ) Tj ET Q q 0 0 0 rg BT 325.94 482.85 Td (our ) Tj ET Q q 0 0 0 rg BT 341.77 482.85 Td (R&D ) Tj ET Q q 0 0 0 rg BT 365.94 482.85 Td (program ) Tj ET Q q 0 0 0 rg BT 402.31 482.85 Td (strategy) Tj ET Q q 0 0 0 rg BT 433.32 482.85 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (Drug ) Tj ET Q q 0 0 0 rg BT 59.11 461.25 Td (development ) Tj ET Q q 0 0 0 rg BT 113.32 461.25 Td (is ) Tj ET Q q 0 0 0 rg BT 122.54 461.25 Td (time ) Tj ET Q q 0 0 0 rg BT 142.88 461.25 Td (consuming, ) Tj ET Q q 0 0 0 rg BT 191.82 461.25 Td (expensive ) Tj ET Q q 0 0 0 rg BT 234.36 461.25 Td (and ) Tj ET Q q 0 0 0 rg BT 251.36 461.25 Td (risky) Tj ET Q q 0 0 0 rg BT 270.71 461.25 Td (. ) Tj ET Q q 0 0 0 rg BT 275.58 461.25 Td (The ) Tj ET Q q 0 0 0 rg BT 293.69 461.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 317.91 461.25 Td (process ) Tj ET Q q 0 0 0 rg BT 350.46 461.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 388.01 461.25 Td (takes ) Tj ET Q q 0 0 0 rg BT 411.11 461.25 Td (about ) Tj ET Q q 0 0 0 rg BT 435.89 461.25 Td (fourteen ) Tj ET Q q 0 0 0 rg BT 471.76 461.25 Td (years, ) Tj ET Q q 0 0 0 rg BT 497.92 461.25 Td (with ) Tj ET Q q 0 0 0 rg BT 518.25 461.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (two ) Tj ET Q q 0 0 0 rg BT 54.01 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 71.46 449.25 Td (a ) Tj ET Q q 0 0 0 rg BT 78.91 449.25 Td (half ) Tj ET Q q 0 0 0 rg BT 97.46 449.25 Td (years ) Tj ET Q q 0 0 0 rg BT 121.57 449.25 Td (often ) Tj ET Q q 0 0 0 rg BT 145.13 449.25 Td (spent ) Tj ET Q q 0 0 0 rg BT 169.25 449.25 Td (in ) Tj ET Q q 0 0 0 rg BT 180.04 449.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 206.38 449.25 Td (III, ) Tj ET Q q 0 0 0 rg BT 221.88 449.25 Td (or ) Tj ET Q q 0 0 0 rg BT 233.22 449.25 Td (late-stage, ) Tj ET Q q 0 0 0 rg BT 277.04 449.25 Td (development. ) Tj ET Q q 0 0 0 rg BT 334.20 449.25 Td (On ) Tj ET Q q 0 0 0 rg BT 349.43 449.25 Td (average, ) Tj ET Q q 0 0 0 rg BT 386.03 449.25 Td (only ) Tj ET Q q 0 0 0 rg BT 406.82 449.25 Td (about ) Tj ET Q q 0 0 0 rg BT 432.04 449.25 Td (one ) Tj ET Q q 0 0 0 rg BT 449.49 449.25 Td (in ) Tj ET Q q 0 0 0 rg BT 460.28 449.25 Td (10,000 ) Tj ET Q q 0 0 0 rg BT 490.79 449.25 Td (chemical ) Tj ET Q q 0 0 0 rg BT 529.89 449.25 Td (compounds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (discovered ) Tj ET Q q 0 0 0 rg BT 80.84 437.25 Td (by ) Tj ET Q q 0 0 0 rg BT 92.36 437.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 154.95 437.25 Td (industry ) Tj ET Q q 0 0 0 rg BT 189.25 437.25 Td (researchers ) Tj ET Q q 0 0 0 rg BT 235.73 437.25 Td (proves ) Tj ET Q q 0 0 0 rg BT 263.91 437.25 Td (to ) Tj ET Q q 0 0 0 rg BT 273.21 437.25 Td (be ) Tj ET Q q 0 0 0 rg BT 284.17 437.25 Td (both ) Tj ET Q q 0 0 0 rg BT 303.47 437.25 Td (medically ) Tj ET Q q 0 0 0 rg BT 344.42 437.25 Td (ef) Tj ET Q q 0 0 0 rg BT 352.01 437.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 380.73 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 396.69 437.25 Td (safe ) Tj ET Q q 0 0 0 rg BT 414.31 437.25 Td (enough ) Tj ET Q q 0 0 0 rg BT 445.26 437.25 Td (to ) Tj ET Q q 0 0 0 rg BT 454.56 437.25 Td (become ) Tj ET Q q 0 0 0 rg BT 487.18 437.25 Td (an ) Tj ET Q q 0 0 0 rg BT 498.13 437.25 Td (approved ) Tj ET Q q 0 0 0 rg BT 536.86 437.25 Td (medicine. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (Drug ) Tj ET Q q 0 0 0 rg BT 58.51 425.25 Td (candidates ) Tj ET Q q 0 0 0 rg BT 102.67 425.25 Td (can ) Tj ET Q q 0 0 0 rg BT 118.50 425.25 Td (fail ) Tj ET Q q 0 0 0 rg BT 133.78 425.25 Td (at ) Tj ET Q q 0 0 0 rg BT 142.95 425.25 Td (any ) Tj ET Q q 0 0 0 rg BT 159.34 425.25 Td (stage ) Tj ET Q q 0 0 0 rg BT 181.85 425.25 Td (of ) Tj ET Q q 0 0 0 rg BT 192.13 425.25 Td (the ) Tj ET Q q 0 0 0 rg BT 206.31 425.25 Td (process, ) Tj ET Q q 0 0 0 rg BT 240.75 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 257.15 425.25 Td (even ) Tj ET Q q 0 0 0 rg BT 277.98 425.25 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 318.24 425.25 Td (product ) Tj ET Q q 0 0 0 rg BT 350.75 425.25 Td (candidates ) Tj ET Q q 0 0 0 rg BT 394.90 425.25 Td (sometimes ) Tj ET Q q 0 0 0 rg BT 439.63 425.25 Td (fail ) Tj ET Q q 0 0 0 rg BT 454.91 425.25 Td (to ) Tj ET Q q 0 0 0 rg BT 464.65 425.25 Td (receive ) Tj ET Q q 0 0 0 rg BT 495.47 425.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 538.51 425.25 Td (approval. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (According ) Tj ET Q q 0 0 0 rg BT 81.11 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 91.79 413.25 Td (the ) Tj ET Q q 0 0 0 rg BT 106.90 413.25 Td (KMR ) Tj ET Q q 0 0 0 rg BT 132.59 413.25 Td (Group, ) Tj ET Q q 0 0 0 rg BT 163.54 413.25 Td (based ) Tj ET Q q 0 0 0 rg BT 189.21 413.25 Td (on ) Tj ET Q q 0 0 0 rg BT 202.11 413.25 Td (industry ) Tj ET Q q 0 0 0 rg BT 237.79 413.25 Td (success ) Tj ET Q q 0 0 0 rg BT 270.68 413.25 Td (rates ) Tj ET Q q 0 0 0 rg BT 292.46 413.25 Td (from ) Tj ET Q q 0 0 0 rg BT 314.79 413.25 Td (2012-2016, ) Tj ET Q q 0 0 0 rg BT 363.52 413.25 Td (approximately ) Tj ET Q q 0 0 0 rg BT 424.18 413.25 Td (92% ) Tj ET Q q 0 0 0 rg BT 445.41 413.25 Td (of ) Tj ET Q q 0 0 0 rg BT 456.64 413.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 505.65 413.25 Td (that ) Tj ET Q q 0 0 0 rg BT 523.55 413.25 Td (enter ) Tj ET Q q 0 0 0 rg BT 546.43 413.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 572.67 413.25 Td (I ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (development ) Tj ET Q q 0 0 0 rg BT 90.12 401.25 Td (fail ) Tj ET Q q 0 0 0 rg BT 105.91 401.25 Td (to ) Tj ET Q q 0 0 0 rg BT 116.15 401.25 Td (achieve ) Tj ET Q q 0 0 0 rg BT 149.15 401.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 192.70 401.25 Td (approval. ) Tj ET Q q 0 0 0 rg BT 232.65 401.25 Td (Compounds ) Tj ET Q q 0 0 0 rg BT 283.46 401.25 Td (that ) Tj ET Q q 0 0 0 rg BT 300.92 401.25 Td (enter ) Tj ET Q q 0 0 0 rg BT 323.37 401.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 349.16 401.25 Td (II ) Tj ET Q q 0 0 0 rg BT 358.29 401.25 Td (development ) Tj ET Q q 0 0 0 rg BT 412.40 401.25 Td (have ) Tj ET Q q 0 0 0 rg BT 433.75 401.25 Td (a ) Tj ET Q q 0 0 0 rg BT 440.65 401.25 Td (failure ) Tj ET Q q 0 0 0 rg BT 469.21 401.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 486.66 401.25 Td (of ) Tj ET Q q 0 0 0 rg BT 497.45 401.25 Td (approximately ) Tj ET Q q 0 0 0 rg BT 557.68 401.25 Td (80% ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (while ) Tj ET Q q 0 0 0 rg BT 60.72 389.25 Td (approximately ) Tj ET Q q 0 0 0 rg BT 120.98 389.25 Td (30% ) Tj ET Q q 0 0 0 rg BT 141.81 389.25 Td (fail ) Tj ET Q q 0 0 0 rg BT 157.63 389.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 183.46 389.25 Td (III ) Tj ET Q q 0 0 0 rg BT 195.95 389.25 Td (development.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.25 Td (T) Tj ET Q q 0 0 0 rg BT 41.41 365.25 Td (otal ) Tj ET Q q 0 0 0 rg BT 59.48 365.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 84.23 365.25 Td (expenses ) Tj ET Q q 0 0 0 rg BT 123.41 365.25 Td (include ) Tj ET Q q 0 0 0 rg BT 155.92 365.25 Td (the ) Tj ET Q q 0 0 0 rg BT 171.21 365.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 194.29 365.25 Td (of ) Tj ET Q q 0 0 0 rg BT 205.70 365.25 Td (discovery ) Tj ET Q q 0 0 0 rg BT 247.65 365.25 Td (research, ) Tj ET Q q 0 0 0 rg BT 286.54 365.25 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 331.81 365.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 389.04 365.25 Td (early- ) Tj ET Q q 0 0 0 rg BT 415.43 365.25 Td (and ) Tj ET Q q 0 0 0 rg BT 432.95 365.25 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 474.34 365.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 506.84 365.25 Td (development ) Tj ET Q q 0 0 0 rg BT 561.57 365.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 56.79 353.25 Td (formulation, ) Tj ET Q q 0 0 0 rg BT 108.95 353.25 Td (as ) Tj ET Q q 0 0 0 rg BT 119.74 353.25 Td (well ) Tj ET Q q 0 0 0 rg BT 139.41 353.25 Td (as ) Tj ET Q q 0 0 0 rg BT 150.20 353.25 Td (post-commercialization ) Tj ET Q q 0 0 0 rg BT 247.06 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 263.96 353.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 298.07 353.25 Td (support ) Tj ET Q q 0 0 0 rg BT 330.52 353.25 Td (of ) Tj ET Q q 0 0 0 rg BT 341.31 353.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 380.97 353.25 Td (products, ) Tj ET Q q 0 0 0 rg BT 420.36 353.25 Td (proportionate ) Tj ET Q q 0 0 0 rg BT 476.69 353.25 Td (allocations ) Tj ET Q q 0 0 0 rg BT 522.46 353.25 Td (of ) Tj ET Q q 0 0 0 rg BT 533.25 353.25 Td (enterprise-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (wide ) Tj ET Q q 0 0 0 rg BT 58.33 341.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 81.23 341.25 Td (and ) Tj ET Q q 0 0 0 rg BT 98.56 341.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 137.56 341.25 Td (and ) Tj ET Q q 0 0 0 rg BT 154.89 341.25 Td (acquiring ) Tj ET Q q 0 0 0 rg BT 195.55 341.25 Td (assets. ) Tj ET Q q 0 0 0 rg BT 224.27 341.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 248.84 341.25 Td (expenses ) Tj ET Q q 0 0 0 rg BT 287.83 341.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.16 341.25 Td ($6.4 ) Tj ET Q q 0 0 0 rg BT 330.55 341.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.66 341.25 Td ( ) Tj ET Q q 0 0 0 rg BT 359.56 341.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.23 341.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.23 341.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 395.63 341.25 Td ($4.9 ) Tj ET Q q 0 0 0 rg BT 416.02 341.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 442.13 341.25 Td ( ) Tj ET Q q 0 0 0 rg BT 445.03 341.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.70 341.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.70 341.25 Td ( ) Tj ET Q q 0 0 0 rg BT 478.59 341.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.93 341.25 Td ($5.9 ) Tj ET Q q 0 0 0 rg BT 516.32 341.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 542.44 341.25 Td ( ) Tj ET Q q 0 0 0 rg BT 545.33 341.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.00 341.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.25 Td (including ) Tj ET Q q 0 0 0 rg BT 76.93 329.25 Td (license ) Tj ET Q q 0 0 0 rg BT 107.85 329.25 Td (and ) Tj ET Q q 0 0 0 rg BT 125.45 329.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 148.05 329.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 195.09 329.25 Td (char) Tj ET Q q 0 0 0 rg BT 212.11 329.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 228.60 329.25 Td (of ) Tj ET Q q 0 0 0 rg BT 240.09 329.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.01 329.25 Td ($1.1 ) Tj ET Q q 0 0 0 rg BT 321.67 329.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.78 329.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.44 329.25 Td ($440 ) Tj ET Q q 0 0 0 rg BT 376.59 329.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.49 329.25 Td ( ) Tj ET Q q 0 0 0 rg BT 408.64 329.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.24 329.25 Td ($1.7 ) Tj ET Q q 0 0 0 rg BT 446.90 329.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.01 329.25 Td ( ) Tj ET Q q 0 0 0 rg BT 476.17 329.25 Td (in ) Tj ET Q q 0 0 0 rg BT 487.11 329.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 512.77 329.25 Td (2016 ) Tj ET Q q 0 0 0 rg BT 535.92 329.25 Td (and ) Tj ET Q q 0 0 0 rg BT 553.52 329.25 Td (2015, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.25 Td (respectively) Tj ET Q q 0 0 0 rg BT 83.66 317.25 Td (. ) Tj ET Q q 0 0 0 rg BT 87.81 317.25 Td (At ) Tj ET Q q 0 0 0 rg BT 99.92 317.25 Td (the ) Tj ET Q q 0 0 0 rg BT 114.25 317.25 Td (end ) Tj ET Q q 0 0 0 rg BT 130.80 317.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 141.25 317.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 161.25 317.25 Td (, ) Tj ET Q q 0 0 0 rg BT 165.86 317.25 Td (we ) Tj ET Q q 0 0 0 rg BT 179.63 317.25 Td (employed ) Tj ET Q q 0 0 0 rg BT 221.18 317.25 Td (approximately ) Tj ET Q q 0 0 0 rg BT 281.05 317.25 Td (7,700 ) Tj ET Q q 0 0 0 rg BT 305.67 317.25 Td (people ) Tj ET Q q 0 0 0 rg BT 334.43 317.25 Td (in ) Tj ET Q q 0 0 0 rg BT 344.33 317.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 368.11 317.25 Td (and ) Tj ET Q q 0 0 0 rg BT 384.66 317.25 Td (related ) Tj ET Q q 0 0 0 rg BT 413.98 317.25 Td (support ) Tj ET Q q 0 0 0 rg BT 446.09 317.25 Td (activities, ) Tj ET Q q 0 0 0 rg BT 486.80 317.25 Td (including ) Tj ET Q q 0 0 0 rg BT 526.69 317.25 Td (a ) Tj ET Q q 0 0 0 rg BT 533.24 317.25 Td (substantial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.25 Td (number ) Tj ET Q q 0 0 0 rg BT 69.05 305.25 Td (of ) Tj ET Q q 0 0 0 rg BT 79.88 305.25 Td (physicians, ) Tj ET Q q 0 0 0 rg BT 127.09 305.25 Td (scientists ) Tj ET Q q 0 0 0 rg BT 166.26 305.25 Td (holding ) Tj ET Q q 0 0 0 rg BT 199.32 305.25 Td (graduate ) Tj ET Q q 0 0 0 rg BT 236.24 305.25 Td (or ) Tj ET Q q 0 0 0 rg BT 247.07 305.25 Td (postgraduate ) Tj ET Q q 0 0 0 rg BT 300.66 305.25 Td (degrees ) Tj ET Q q 0 0 0 rg BT 333.70 305.25 Td (and ) Tj ET Q q 0 0 0 rg BT 350.64 305.25 Td (higher) Tj ET Q q 0 0 0 rg BT 375.99 305.25 Td (-skilled ) Tj ET Q q 0 0 0 rg BT 408.48 305.25 Td (technical ) Tj ET Q q 0 0 0 rg BT 447.07 305.25 Td (personnel.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 283.65 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 283.65 Td (e ) Tj ET Q q 0 0 0 rg BT 51.69 283.65 Td (manage ) Tj ET Q q 0 0 0 rg BT 85.40 283.65 Td (our ) Tj ET Q q 0 0 0 rg BT 101.35 283.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 125.64 283.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 166.02 283.65 Td (on ) Tj ET Q q 0 0 0 rg BT 178.64 283.65 Td (a ) Tj ET Q q 0 0 0 rg BT 185.70 283.65 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 223.31 283.65 Td (basis, ) Tj ET Q q 0 0 0 rg BT 248.43 283.65 Td (investing ) Tj ET Q q 0 0 0 rg BT 287.71 283.65 Td (resources ) Tj ET Q q 0 0 0 rg BT 328.08 283.65 Td (in ) Tj ET Q q 0 0 0 rg BT 338.48 283.65 Td (each ) Tj ET Q q 0 0 0 rg BT 359.41 283.65 Td (stage ) Tj ET Q q 0 0 0 rg BT 382.58 283.65 Td (of ) Tj ET Q q 0 0 0 rg BT 393.52 283.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 417.81 283.65 Td (from ) Tj ET Q q 0 0 0 rg BT 439.87 283.65 Td (early ) Tj ET Q q 0 0 0 rg BT 462.47 283.65 Td (discovery ) Tj ET Q q 0 0 0 rg BT 503.96 283.65 Td (through ) Tj ET Q q 0 0 0 rg BT 537.69 283.65 Td (late-stage ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 271.65 Td (development. ) Tj ET Q q 0 0 0 rg BT 92.36 271.65 Td (W) Tj ET Q q 0 0 0 rg BT 100.99 271.65 Td (e ) Tj ET Q q 0 0 0 rg BT 107.81 271.65 Td (continually ) Tj ET Q q 0 0 0 rg BT 155.18 271.65 Td (evaluate ) Tj ET Q q 0 0 0 rg BT 190.87 271.65 Td (our ) Tj ET Q q 0 0 0 rg BT 206.58 271.65 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 243.95 271.65 Td (of ) Tj ET Q q 0 0 0 rg BT 254.66 271.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 278.70 271.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 304.41 271.65 Td (to ) Tj ET Q q 0 0 0 rg BT 314.57 271.65 Td (ensure ) Tj ET Q q 0 0 0 rg BT 343.04 271.65 Td (that ) Tj ET Q q 0 0 0 rg BT 360.42 271.65 Td (there ) Tj ET Q q 0 0 0 rg BT 382.78 271.65 Td (is ) Tj ET Q q 0 0 0 rg BT 391.83 271.65 Td (an ) Tj ET Q q 0 0 0 rg BT 403.65 271.65 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 451.56 271.65 Td (balance ) Tj ET Q q 0 0 0 rg BT 484.47 271.65 Td (of ) Tj ET Q q 0 0 0 rg BT 495.17 271.65 Td (early-stage ) Tj ET Q q 0 0 0 rg BT 541.41 271.65 Td (and ) Tj ET Q q 0 0 0 rg BT 558.23 271.65 Td (late-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 259.65 Td (stage ) Tj ET Q q 0 0 0 rg BT 58.05 259.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 97.32 259.65 Td (to ) Tj ET Q q 0 0 0 rg BT 106.60 259.65 Td (support ) Tj ET Q q 0 0 0 rg BT 138.10 259.65 Td (the ) Tj ET Q q 0 0 0 rg BT 151.82 259.65 Td (future ) Tj ET Q q 0 0 0 rg BT 177.20 259.65 Td (growth ) Tj ET Q q 0 0 0 rg BT 207.03 259.65 Td (of ) Tj ET Q q 0 0 0 rg BT 216.86 259.65 Td (the ) Tj ET Q q 0 0 0 rg BT 230.58 259.65 Td (Company) Tj ET Q q 0 0 0 rg BT 268.81 259.65 Td (. ) Tj ET Q q 0 0 0 rg BT 272.82 259.65 Td (Spending ) Tj ET Q q 0 0 0 rg BT 312.10 259.65 Td (on ) Tj ET Q q 0 0 0 rg BT 323.60 259.65 Td (our ) Tj ET Q q 0 0 0 rg BT 338.43 259.65 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 378.24 259.65 Td (development ) Tj ET Q q 0 0 0 rg BT 431.39 259.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 470.66 259.65 Td (represented ) Tj ET Q q 0 0 0 rg BT 518.25 259.65 Td (approximately) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 247.65 Td (30-45% ) Tj ET Q q 0 0 0 rg BT 69.71 247.65 Td (of ) Tj ET Q q 0 0 0 rg BT 80.09 247.65 Td (our ) Tj ET Q q 0 0 0 rg BT 95.47 247.65 Td (annual ) Tj ET Q q 0 0 0 rg BT 124.17 247.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 147.89 247.65 Td (expenses ) Tj ET Q q 0 0 0 rg BT 186.03 247.65 Td (in ) Tj ET Q q 0 0 0 rg BT 195.86 247.65 Td (the ) Tj ET Q q 0 0 0 rg BT 210.13 247.65 Td (last ) Tj ET Q q 0 0 0 rg BT 226.06 247.65 Td (three ) Tj ET Q q 0 0 0 rg BT 248.09 247.65 Td (years. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 273.74 247.65 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.18 247.65 Td ( ) Tj ET Q q 0 0 0 rg BT 305.23 247.65 Td (is ) Tj ET Q q 0 0 0 rg BT 313.95 247.65 Td (the ) Tj ET Q q 0 0 0 rg BT 328.21 247.65 Td (only ) Tj ET Q q 0 0 0 rg BT 348.04 247.65 Td (individual ) Tj ET Q q 0 0 0 rg BT 390.64 247.65 Td (investigational ) Tj ET Q q 0 0 0 rg BT 451.56 247.65 Td (compound ) Tj ET Q q 0 0 0 rg BT 495.83 247.65 Td (or ) Tj ET Q q 0 0 0 rg BT 506.21 247.65 Td (marketed ) Tj ET Q q 0 0 0 rg BT 545.46 247.65 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 235.65 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 235.65 Td (represent ) Tj ET Q q 0 0 0 rg BT 85.42 235.65 Td (10% ) Tj ET Q q 0 0 0 rg BT 106.25 235.65 Td (or ) Tj ET Q q 0 0 0 rg BT 117.08 235.65 Td (more ) Tj ET Q q 0 0 0 rg BT 140.13 235.65 Td (of ) Tj ET Q q 0 0 0 rg BT 150.96 235.65 Td (our ) Tj ET Q q 0 0 0 rg BT 166.79 235.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 190.96 235.65 Td (expenses ) Tj ET Q q 0 0 0 rg BT 229.56 235.65 Td (in ) Tj ET Q q 0 0 0 rg BT 239.84 235.65 Td (any ) Tj ET Q q 0 0 0 rg BT 256.78 235.65 Td (of ) Tj ET Q q 0 0 0 rg BT 267.61 235.65 Td (the ) Tj ET Q q 0 0 0 rg BT 282.32 235.65 Td (last ) Tj ET Q q 0 0 0 rg BT 298.71 235.65 Td (three ) Tj ET Q q 0 0 0 rg BT 321.20 235.65 Td (years.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 211.65 Td (As ) Tj ET Q q 0 0 0 rg BT 49.82 211.65 Td (part ) Tj ET Q q 0 0 0 rg BT 68.08 211.65 Td (of ) Tj ET Q q 0 0 0 rg BT 79.12 211.65 Td (our ) Tj ET Q q 0 0 0 rg BT 95.17 211.65 Td (operating ) Tj ET Q q 0 0 0 rg BT 135.64 211.65 Td (model ) Tj ET Q q 0 0 0 rg BT 163.35 211.65 Td (evolution, ) Tj ET Q q 0 0 0 rg BT 206.33 211.65 Td (our ) Tj ET Q q 0 0 0 rg BT 222.37 211.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 246.76 211.65 Td (geographic ) Tj ET Q q 0 0 0 rg BT 293.89 211.65 Td (footprint ) Tj ET Q q 0 0 0 rg BT 331.60 211.65 Td (will ) Tj ET Q q 0 0 0 rg BT 349.87 211.65 Td (significantly ) Tj ET Q q 0 0 0 rg BT 402.57 211.65 Td (transform ) Tj ET Q q 0 0 0 rg BT 444.16 211.65 Td (to ) Tj ET Q q 0 0 0 rg BT 454.65 211.65 Td (foster ) Tj ET Q q 0 0 0 rg BT 480.13 211.65 Td (speed ) Tj ET Q q 0 0 0 rg BT 505.60 211.65 Td (and ) Tj ET Q q 0 0 0 rg BT 522.75 211.65 Td (innovation ) Tj ET Q q 0 0 0 rg BT 568.24 211.65 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 199.65 Td (the ) Tj ET Q q 0 0 0 rg BT 50.56 199.65 Td (future. ) Tj ET Q q 0 0 0 rg BT 79.12 199.65 Td (The ) Tj ET Q q 0 0 0 rg BT 97.01 199.65 Td (transformation ) Tj ET Q q 0 0 0 rg BT 158.23 199.65 Td (involves ) Tj ET Q q 0 0 0 rg BT 194.47 199.65 Td (the ) Tj ET Q q 0 0 0 rg BT 209.03 199.65 Td (closing ) Tj ET Q q 0 0 0 rg BT 240.27 199.65 Td (of ) Tj ET Q q 0 0 0 rg BT 250.94 199.65 Td (our ) Tj ET Q q 0 0 0 rg BT 266.62 199.65 Td (Hopewell, ) Tj ET Q q 0 0 0 rg BT 310.35 199.65 Td (New ) Tj ET Q q 0 0 0 rg BT 331.58 199.65 Td (Jersey ) Tj ET Q q 0 0 0 rg BT 358.91 199.65 Td (and ) Tj ET Q q 0 0 0 rg BT 375.53 199.65 Td (W) Tj ET Q q 0 0 0 rg BT 384.17 199.65 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 428.45 199.65 Td (Connecticut ) Tj ET Q q 0 0 0 rg BT 479.12 199.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 503.13 199.65 Td (sites ) Tj ET Q q 0 0 0 rg BT 523.26 199.65 Td (accompanied ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 187.65 Td (by ) Tj ET Q q 0 0 0 rg BT 48.98 187.65 Td (additional ) Tj ET Q q 0 0 0 rg BT 91.94 187.65 Td (investment ) Tj ET Q q 0 0 0 rg BT 138.80 187.65 Td (in ) Tj ET Q q 0 0 0 rg BT 149.55 187.65 Td (the ) Tj ET Q q 0 0 0 rg BT 164.75 187.65 Td (expansion ) Tj ET Q q 0 0 0 rg BT 208.27 187.65 Td (and ) Tj ET Q q 0 0 0 rg BT 225.69 187.65 Td (opening ) Tj ET Q q 0 0 0 rg BT 260.88 187.65 Td (of ) Tj ET Q q 0 0 0 rg BT 272.18 187.65 Td (others. ) Tj ET Q q 0 0 0 rg BT 302.10 187.65 Td (For ) Tj ET Q q 0 0 0 rg BT 318.97 187.65 Td (example, ) Tj ET Q q 0 0 0 rg BT 358.31 187.65 Td (we ) Tj ET Q q 0 0 0 rg BT 372.95 187.65 Td (are ) Tj ET Q q 0 0 0 rg BT 388.13 187.65 Td (expanding ) Tj ET Q q 0 0 0 rg BT 432.77 187.65 Td (our ) Tj ET Q q 0 0 0 rg BT 449.07 187.65 Td (Lawrenceville, ) Tj ET Q q 0 0 0 rg BT 511.73 187.65 Td (New ) Tj ET Q q 0 0 0 rg BT 533.59 187.65 Td (Jersey ) Tj ET Q q 0 0 0 rg BT 561.56 187.65 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 175.65 Td (Redwood ) Tj ET Q q 0 0 0 rg BT 76.76 175.65 Td (City) Tj ET Q q 0 0 0 rg BT 93.34 175.65 Td (, ) Tj ET Q q 0 0 0 rg BT 98.28 175.65 Td (California ) Tj ET Q q 0 0 0 rg BT 141.25 175.65 Td (sites ) Tj ET Q q 0 0 0 rg BT 161.46 175.65 Td (and ) Tj ET Q q 0 0 0 rg BT 178.34 175.65 Td (plan ) Tj ET Q q 0 0 0 rg BT 197.99 175.65 Td (to ) Tj ET Q q 0 0 0 rg BT 208.20 175.65 Td (open ) Tj ET Q q 0 0 0 rg BT 230.07 175.65 Td (a ) Tj ET Q q 0 0 0 rg BT 236.94 175.65 Td (new ) Tj ET Q q 0 0 0 rg BT 256.04 175.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 280.14 175.65 Td (facility ) Tj ET Q q 0 0 0 rg BT 310.90 175.65 Td (in ) Tj ET Q q 0 0 0 rg BT 321.11 175.65 Td (Cambridge, ) Tj ET Q q 0 0 0 rg BT 370.48 175.65 Td (Massachusetts ) Tj ET Q q 0 0 0 rg BT 430.68 175.65 Td (in ) Tj ET Q q 0 0 0 rg BT 440.89 175.65 Td (2018. ) Tj ET Q q 0 0 0 rg BT 465.65 175.65 Td (W) Tj ET Q q 0 0 0 rg BT 474.29 175.65 Td (e ) Tj ET Q q 0 0 0 rg BT 481.16 175.65 Td (supplement ) Tj ET Q q 0 0 0 rg BT 529.70 175.65 Td (our ) Tj ET Q q 0 0 0 rg BT 545.46 175.65 Td (internal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 163.65 Td (drug ) Tj ET Q q 0 0 0 rg BT 57.94 163.65 Td (discovery ) Tj ET Q q 0 0 0 rg BT 100.42 163.65 Td (and ) Tj ET Q q 0 0 0 rg BT 118.46 163.65 Td (development ) Tj ET Q q 0 0 0 rg BT 173.72 163.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 215.09 163.65 Td (with ) Tj ET Q q 0 0 0 rg BT 236.47 163.65 Td (alliances ) Tj ET Q q 0 0 0 rg BT 275.06 163.65 Td (and ) Tj ET Q q 0 0 0 rg BT 293.10 163.65 Td (collaborative ) Tj ET Q q 0 0 0 rg BT 348.90 163.65 Td (agreements ) Tj ET Q q 0 0 0 rg BT 398.04 163.65 Td (which ) Tj ET Q q 0 0 0 rg BT 426.08 163.65 Td (help ) Tj ET Q q 0 0 0 rg BT 446.91 163.65 Td (us ) Tj ET Q q 0 0 0 rg BT 459.40 163.65 Td (bring ) Tj ET Q q 0 0 0 rg BT 484.12 163.65 Td (new ) Tj ET Q q 0 0 0 rg BT 504.38 163.65 Td (molecular ) Tj ET Q q 0 0 0 rg BT 547.97 163.65 Td (agents, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 151.65 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 84.82 151.65 Td (and ) Tj ET Q q 0 0 0 rg BT 102.55 151.65 Td (platforms ) Tj ET Q q 0 0 0 rg BT 144.16 151.65 Td (into ) Tj ET Q q 0 0 0 rg BT 163.01 151.65 Td (our ) Tj ET Q q 0 0 0 rg BT 179.63 151.65 Td (pipeline. ) Tj ET Q q 0 0 0 rg BT 217.63 151.65 Td (Management ) Tj ET Q q 0 0 0 rg BT 273.11 151.65 Td (continues ) Tj ET Q q 0 0 0 rg BT 314.73 151.65 Td (to ) Tj ET Q q 0 0 0 rg BT 325.79 151.65 Td (emphasize ) Tj ET Q q 0 0 0 rg BT 371.28 151.65 Td (leadership, ) Tj ET Q q 0 0 0 rg BT 418.16 151.65 Td (innovation, ) Tj ET Q q 0 0 0 rg BT 466.73 151.65 Td (productivity ) Tj ET Q q 0 0 0 rg BT 518.90 151.65 Td (and ) Tj ET Q q 0 0 0 rg BT 536.62 151.65 Td (quality ) Tj ET Q q 0 0 0 rg BT 567.68 151.65 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 139.65 Td (strategies ) Tj ET Q q 0 0 0 rg BT 76.26 139.65 Td (for ) Tj ET Q q 0 0 0 rg BT 90.42 139.65 Td (success ) Tj ET Q q 0 0 0 rg BT 122.91 139.65 Td (in ) Tj ET Q q 0 0 0 rg BT 133.19 139.65 Td (our ) Tj ET Q q 0 0 0 rg BT 149.02 139.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 173.19 139.65 Td (activities.) Tj ET Q endstream endobj 19 0 obj <> endobj 20 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.50 24.60 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Listed ) Tj ET Q q 0 0 0 rg BT 63.28 749.10 Td (below ) Tj ET Q q 0 0 0 rg BT 90.00 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 104.49 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 120.10 749.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 181.26 749.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 229.65 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 246.93 749.10 Td (we ) Tj ET Q q 0 0 0 rg BT 260.87 749.10 Td (have ) Tj ET Q q 0 0 0 rg BT 282.03 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 292.09 749.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 323.81 749.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 353.87 749.10 Td (as ) Tj ET Q q 0 0 0 rg BT 364.48 749.10 Td (well ) Tj ET Q q 0 0 0 rg BT 383.98 749.10 Td (as ) Tj ET Q q 0 0 0 rg BT 394.59 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 409.09 749.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 448.58 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 465.30 749.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 502.57 749.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 548.74 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 562.68 749.10 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 76.47 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 114.18 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 125.23 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 140.72 737.10 Td (related ) Tj ET Q q 0 0 0 rg BT 171.20 737.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 218.89 737.10 Td (area ) Tj ET Q q 0 0 0 rg BT 238.80 737.10 Td (as ) Tj ET Q q 0 0 0 rg BT 250.40 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 262.01 737.10 Td (January ) Tj ET Q q 0 0 0 rg BT 296.38 737.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 307.15 737.10 Td (2018. ) Tj ET Q q 0 0 0 rg BT 332.68 737.10 Td (Whether ) Tj ET Q q 0 0 0 rg BT 370.38 737.10 Td (any ) Tj ET Q q 0 0 0 rg BT 388.09 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 399.69 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 415.18 737.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 440.11 737.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 489.49 737.10 Td (ultimately ) Tj ET Q q 0 0 0 rg BT 533.31 737.10 Td (becomes ) Tj ET Q q 0 0 0 rg BT 571.57 737.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 75.63 725.10 Td (product ) Tj ET Q q 0 0 0 rg BT 108.61 725.10 Td (depends ) Tj ET Q q 0 0 0 rg BT 143.80 725.10 Td (on ) Tj ET Q q 0 0 0 rg BT 156.23 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 170.88 725.10 Td (results ) Tj ET Q q 0 0 0 rg BT 199.41 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 210.17 725.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 242.03 725.10 Td (studies, ) Tj ET Q q 0 0 0 rg BT 274.73 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 289.38 725.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 339.01 725.10 Td (landscape ) Tj ET Q q 0 0 0 rg BT 380.87 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 391.62 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 406.27 725.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 443.69 725.10 Td (product’) Tj ET Q q 0 0 0 rg BT 477.01 725.10 Td (s ) Tj ET Q q 0 0 0 rg BT 483.33 725.10 Td (market, ) Tj ET Q q 0 0 0 rg BT 516.02 725.10 Td (reimbursement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (decisions ) Tj ET Q q 0 0 0 rg BT 76.27 713.10 Td (by ) Tj ET Q q 0 0 0 rg BT 89.32 713.10 Td (payers ) Tj ET Q q 0 0 0 rg BT 118.47 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 135.96 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 151.22 713.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 212.59 713.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 253.96 713.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 295.88 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 306.70 713.10 Td (produce ) Tj ET Q q 0 0 0 rg BT 341.96 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 357.23 713.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 395.27 713.10 Td (product ) Tj ET Q q 0 0 0 rg BT 428.87 713.10 Td (on ) Tj ET Q q 0 0 0 rg BT 441.92 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 449.41 713.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 499.66 713.10 Td (scale, ) Tj ET Q q 0 0 0 rg BT 525.19 713.10 Td (among ) Tj ET Q q 0 0 0 rg BT 555.46 713.10 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (factors. ) Tj ET Q q 0 0 0 rg BT 68.13 701.10 Td (There ) Tj ET Q q 0 0 0 rg BT 94.06 701.10 Td (can ) Tj ET Q q 0 0 0 rg BT 110.55 701.10 Td (be ) Tj ET Q q 0 0 0 rg BT 122.60 701.10 Td (no ) Tj ET Q q 0 0 0 rg BT 135.21 701.10 Td (assurance ) Tj ET Q q 0 0 0 rg BT 176.69 701.10 Td (that ) Tj ET Q q 0 0 0 rg BT 194.30 701.10 Td (we ) Tj ET Q q 0 0 0 rg BT 208.57 701.10 Td (will ) Tj ET Q q 0 0 0 rg BT 226.74 701.10 Td (seek ) Tj ET Q q 0 0 0 rg BT 247.12 701.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 290.83 701.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 328.42 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 339.37 701.10 Td (any ) Tj ET Q q 0 0 0 rg BT 356.42 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 367.36 701.10 Td (these ) Tj ET Q q 0 0 0 rg BT 390.52 701.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 439.24 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 450.18 701.10 Td (that, ) Tj ET Q q 0 0 0 rg BT 470.29 701.10 Td (if ) Tj ET Q q 0 0 0 rg BT 479.01 701.10 Td (such ) Tj ET Q q 0 0 0 rg BT 499.95 701.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 537.55 701.10 Td (is ) Tj ET Q q 0 0 0 rg BT 546.83 701.10 Td (sought, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (it ) Tj ET Q q 0 0 0 rg BT 44.38 689.10 Td (will ) Tj ET Q q 0 0 0 rg BT 62.76 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 75.02 689.10 Td (obtained. ) Tj ET Q q 0 0 0 rg BT 114.57 689.10 Td (There ) Tj ET Q q 0 0 0 rg BT 140.71 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 150.20 689.10 Td (also ) Tj ET Q q 0 0 0 rg BT 169.13 689.10 Td (no ) Tj ET Q q 0 0 0 rg BT 181.95 689.10 Td (assurance ) Tj ET Q q 0 0 0 rg BT 223.64 689.10 Td (that ) Tj ET Q q 0 0 0 rg BT 241.46 689.10 Td (a ) Tj ET Q q 0 0 0 rg BT 248.72 689.10 Td (compound ) Tj ET Q q 0 0 0 rg BT 293.76 689.10 Td (which ) Tj ET Q q 0 0 0 rg BT 321.02 689.10 Td (gets ) Tj ET Q q 0 0 0 rg BT 339.95 689.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 379.98 689.10 Td (will ) Tj ET Q q 0 0 0 rg BT 398.36 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 410.62 689.10 Td (commercially ) Tj ET Q q 0 0 0 rg BT 468.42 689.10 Td (successful. ) Tj ET Q q 0 0 0 rg BT 514.22 689.10 Td (At ) Tj ET Q q 0 0 0 rg BT 527.04 689.10 Td (this ) Tj ET Q q 0 0 0 rg BT 544.31 689.10 Td (stage ) Tj ET Q q 0 0 0 rg BT 567.68 689.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 92.40 677.10 Td (we ) Tj ET Q q 0 0 0 rg BT 106.31 677.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 135.22 677.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 177.45 677.10 Td (all ) Tj ET Q q 0 0 0 rg BT 189.69 677.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 236.37 677.10 Td (property ) Tj ET Q q 0 0 0 rg BT 272.49 677.10 Td (issues ) Tj ET Q q 0 0 0 rg BT 298.63 677.10 Td (or ) Tj ET Q q 0 0 0 rg BT 309.21 677.10 Td (all ) Tj ET Q q 0 0 0 rg BT 321.46 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.93 677.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 362.61 677.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 405.40 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 422.65 677.10 Td (may) Tj ET Q q 0 0 0 rg BT 439.21 677.10 Td (, ) Tj ET Q q 0 0 0 rg BT 443.96 677.10 Td (or ) Tj ET Q q 0 0 0 rg BT 454.54 677.10 Td (may ) Tj ET Q q 0 0 0 rg BT 474.01 677.10 Td (not, ) Tj ET Q q 0 0 0 rg BT 491.54 677.10 Td (be ) Tj ET Q q 0 0 0 rg BT 503.23 677.10 Td (available ) Tj ET Q q 0 0 0 rg BT 541.57 677.10 Td (for ) Tj ET Q q 0 0 0 rg BT 555.48 677.10 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 97.38 665.10 Td (compounds. ) Tj ET Q /GS0 gs q 379.00 0 0 522.00 116.50 126.10 cm /I18 Do Q BT /F1 10.00 Tf ET /GS0 gs q 441.00 0 0 62.00 85.50 59.10 cm /I19 Do Q BT /F1 10.00 Tf ET endstream endobj 21 0 obj <> endobj 22 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (10) Tj ET Q /GS0 gs q 404.00 0 0 445.00 104.00 299.10 cm /I20 Do Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 275.10 Td (As ) Tj ET Q q 0 0 0 rg BT 49.61 275.10 Td (of ) Tj ET Q q 0 0 0 rg BT 60.44 275.10 Td (February ) Tj ET Q q 0 0 0 rg BT 99.04 275.10 Td (5, ) Tj ET Q q 0 0 0 rg BT 109.04 275.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 134.04 275.10 Td (the ) Tj ET Q q 0 0 0 rg BT 148.76 275.10 Td (following ) Tj ET Q q 0 0 0 rg BT 190.15 275.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 227.64 275.10 Td (registrational ) Tj ET Q q 0 0 0 rg BT 282.89 275.10 Td (study ) Tj ET Q q 0 0 0 rg BT 307.06 275.10 Td (readouts ) Tj ET Q q 0 0 0 rg BT 343.44 275.10 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 357.60 275.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.04 275.10 Td ( ) Tj ET Q q 0 0 0 rg BT 389.54 275.10 Td (are ) Tj ET Q q 0 0 0 rg BT 404.25 275.10 Td (anticipated ) Tj ET Q q 0 0 0 rg BT 450.61 275.10 Td (through ) Tj ET Q q 0 0 0 rg BT 484.22 275.10 Td (2019:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 115.50 217.60 190.00 -14.00 re f /GS0 gs 0.7490196078431373 0.8941176470588236 1 rg /GS0 gs 383.50 217.60 190.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 115.50 203.60 190.00 -14.00 re f /GS0 gs 0.8705882352941177 0.9529411764705882 0.7529411764705882 rg /GS0 gs 383.50 203.60 190.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 115.50 189.60 190.00 -14.00 re f /GS0 gs 0.7490196078431373 0.8941176470588236 1 rg /GS0 gs 383.50 189.60 190.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 115.50 175.60 190.00 -28.00 re f /GS0 gs 0.7490196078431373 0.8941176470588236 1 rg /GS0 gs 383.50 175.60 190.00 -21.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 115.50 147.60 190.00 -14.00 re f /GS0 gs 0.8705882352941177 0.9529411764705882 0.7529411764705882 rg /GS0 gs 383.50 147.60 95.00 -14.00 re f /GS0 gs 0.7490196078431373 0.8941176470588236 1 rg /GS0 gs 478.50 147.60 95.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 37.5 232.60000000000002 m 37.5 217.60000000000002 l s 0 0 0 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q 0 0 0 rg BT 231.98 208.06 Td ( line\) Part 1a) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 312.00 203.06 Td (Head and Neck) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 312.00 194.06 Td (Cancer) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 208.06 Td (CM-651 - Opdivo + ) Tj ET Q q 0 0 0 rg BT 460.24 208.06 Td (Y) Tj ET Q q 0 0 0 rg BT 465.84 208.06 Td (ervoy \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 496.08 212.14 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.98 208.06 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 118.00 194.06 Td (CM-227 - Opdivo + Chemo \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 228.32 198.14 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 232.22 194.06 Td ( line\) Part 2) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 194.06 Td (CM-714 - Opdivo + ) Tj ET Q q 0 0 0 rg BT 460.24 194.06 Td (Y) Tj ET Q q 0 0 0 rg BT 465.84 194.06 Td (ervoy \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 496.08 198.14 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.98 194.06 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 118.00 180.06 Td (CM-9LA) Tj ET Q q 0 0 0 rg BT 151.00 180.06 Td ( - Opdivo + ) Tj ET Q q 0 0 0 rg BT 194.74 180.06 Td (Y) Tj ET Q q 0 0 0 rg BT 200.34 180.06 Td (ervoy + Chemo \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 266.15 184.14 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 270.05 180.06 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 312.00 168.06 Td (Small Cell Lung) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 312.00 159.06 Td (Cancer) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 180.06 Td (CM-331 - Opdivo \(2) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 460.75 184.14 Td (nd) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 466.60 180.06 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 40.00 161.06 Td (Hepatocellular) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 40.00 152.06 Td (Carcinoma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 118.00 159.46 Td (CM-459 - Opdivo \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 192.75 163.54 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 196.65 159.46 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 166.86 Td (CM-451 - Opdivo +/- ) Tj ET Q q 0 0 0 rg BT 465.74 166.86 Td (Y) Tj ET Q q 0 0 0 rg BT 471.34 166.86 Td (ervoy \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 501.58 170.94 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 505.48 166.86 Td ( line ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 157.86 Td (Maintenance\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 40.00 138.06 Td (Gastric Cancer) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 118.00 138.06 Td (CM-649 - Opdivo + ) Tj ET Q q 0 0 0 rg BT 192.24 138.06 Td (Y) Tj ET Q q 0 0 0 rg BT 197.84 138.06 Td (ervoy or Chemo \(1) Tj ET Q BT /F1 9.00 Tf ET BT /F1 5.85 Tf ET q 0 0 0 rg BT 266.07 142.14 Td (st) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 269.98 138.06 Td ( line\)) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 312.00 138.06 Td (Key) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.00 138.06 Td (Phase II) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 481.00 138.06 Td (Phase III) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 23 0 obj <> endobj 24 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.15 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 305.78 24.60 Td (1) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (Alliances) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 713.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.38 713.25 Td (enter ) Tj ET Q q 0 0 0 rg BT 73.67 713.25 Td (into ) Tj ET Q q 0 0 0 rg BT 91.52 713.25 Td (alliances ) Tj ET Q q 0 0 0 rg BT 128.81 713.25 Td (with ) Tj ET Q q 0 0 0 rg BT 148.89 713.25 Td (third ) Tj ET Q q 0 0 0 rg BT 170.08 713.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 199.03 713.25 Td (that ) Tj ET Q q 0 0 0 rg BT 216.33 713.25 Td (transfer ) Tj ET Q q 0 0 0 rg BT 249.17 713.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 274.25 713.25 Td (to ) Tj ET Q q 0 0 0 rg BT 284.33 713.25 Td (develop, ) Tj ET Q q 0 0 0 rg BT 320.79 713.25 Td (manufacture, ) Tj ET Q q 0 0 0 rg BT 375.56 713.25 Td (market ) Tj ET Q q 0 0 0 rg BT 405.63 713.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 433.48 713.25 Td (sell ) Tj ET Q q 0 0 0 rg BT 449.67 713.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 513.04 713.25 Td (products. ) Tj ET Q q 0 0 0 rg BT 552.12 713.25 Td (These ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (alliances ) Tj ET Q q 0 0 0 rg BT 74.67 701.25 Td (include ) Tj ET Q q 0 0 0 rg BT 107.79 701.25 Td (licensing, ) Tj ET Q q 0 0 0 rg BT 150.08 701.25 Td (co-development, ) Tj ET Q q 0 0 0 rg BT 220.69 701.25 Td (co-marketing ) Tj ET Q q 0 0 0 rg BT 277.69 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 295.82 701.25 Td (co-promotion ) Tj ET Q q 0 0 0 rg BT 353.94 701.25 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 411.49 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 429.62 701.25 Td (joint ) Tj ET Q q 0 0 0 rg BT 451.64 701.25 Td (ventures. ) Tj ET Q q 0 0 0 rg BT 491.44 701.25 Td (When ) Tj ET Q q 0 0 0 rg BT 519.01 701.25 Td (such ) Tj ET Q q 0 0 0 rg BT 541.03 701.25 Td (alliances ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (involve ) Tj ET Q q 0 0 0 rg BT 68.39 689.25 Td (sharing ) Tj ET Q q 0 0 0 rg BT 100.22 689.25 Td (research ) Tj ET Q q 0 0 0 rg BT 135.91 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 152.74 689.25 Td (development ) Tj ET Q q 0 0 0 rg BT 206.79 689.25 Td (costs, ) Tj ET Q q 0 0 0 rg BT 231.68 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 246.29 689.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 263.68 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 274.40 689.25 Td (incurring ) Tj ET Q q 0 0 0 rg BT 313.45 689.25 Td (all ) Tj ET Q q 0 0 0 rg BT 325.83 689.25 Td (research ) Tj ET Q q 0 0 0 rg BT 361.53 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 378.36 689.25 Td (development ) Tj ET Q q 0 0 0 rg BT 432.40 689.25 Td (expenses ) Tj ET Q q 0 0 0 rg BT 470.89 689.25 Td (for ) Tj ET Q q 0 0 0 rg BT 484.94 689.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 533.44 689.25 Td (that ) Tj ET Q q 0 0 0 rg BT 550.83 689.25 Td (do ) Tj ET Q q 0 0 0 rg BT 563.22 689.25 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 54.19 677.25 Td (to ) Tj ET Q q 0 0 0 rg BT 63.51 677.25 Td (revenue-generating ) Tj ET Q q 0 0 0 rg BT 142.23 677.25 Td (products ) Tj ET Q q 0 0 0 rg BT 178.21 677.25 Td (is ) Tj ET Q q 0 0 0 rg BT 186.42 677.25 Td (reduced. ) Tj ET Q q 0 0 0 rg BT 222.10 677.25 Td (However) Tj ET Q q 0 0 0 rg BT 258.35 677.25 Td (, ) Tj ET Q q 0 0 0 rg BT 262.39 677.25 Td (profitability ) Tj ET Q q 0 0 0 rg BT 311.70 677.25 Td (on ) Tj ET Q q 0 0 0 rg BT 323.24 677.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 355.87 677.25 Td (products ) Tj ET Q q 0 0 0 rg BT 391.85 677.25 Td (is ) Tj ET Q q 0 0 0 rg BT 400.06 677.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 438.80 677.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 463.11 677.25 Td (because ) Tj ET Q q 0 0 0 rg BT 496.29 677.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 523.94 677.25 Td (from ) Tj ET Q q 0 0 0 rg BT 544.92 677.25 Td (alliance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (products ) Tj ET Q q 0 0 0 rg BT 72.77 665.25 Td (are ) Tj ET Q q 0 0 0 rg BT 87.30 665.25 Td (shared ) Tj ET Q q 0 0 0 rg BT 115.73 665.25 Td (with ) Tj ET Q q 0 0 0 rg BT 135.83 665.25 Td (our ) Tj ET Q q 0 0 0 rg BT 151.49 665.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 184.91 665.25 Td (partners. ) Tj ET Q q 0 0 0 rg BT 221.78 665.25 Td (W) Tj ET Q q 0 0 0 rg BT 230.41 665.25 Td (e ) Tj ET Q q 0 0 0 rg BT 237.18 665.25 Td (actively ) Tj ET Q q 0 0 0 rg BT 271.16 665.25 Td (pursue ) Tj ET Q q 0 0 0 rg BT 300.15 665.25 Td (such ) Tj ET Q q 0 0 0 rg BT 320.81 665.25 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 377.00 665.25 Td (and ) Tj ET Q q 0 0 0 rg BT 393.76 665.25 Td (view ) Tj ET Q q 0 0 0 rg BT 415.53 665.25 Td (alliances ) Tj ET Q q 0 0 0 rg BT 452.84 665.25 Td (as ) Tj ET Q q 0 0 0 rg BT 463.50 665.25 Td (an ) Tj ET Q q 0 0 0 rg BT 475.26 665.25 Td (important ) Tj ET Q q 0 0 0 rg BT 516.47 665.25 Td (complement ) Tj ET Q q 0 0 0 rg BT 568.23 665.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (our ) Tj ET Q q 0 0 0 rg BT 51.83 653.25 Td (own ) Tj ET Q q 0 0 0 rg BT 71.55 653.25 Td (discovery) Tj ET Q q 0 0 0 rg BT 109.78 653.25 Td (, ) Tj ET Q q 0 0 0 rg BT 114.78 653.25 Td (development ) Tj ET Q q 0 0 0 rg BT 168.93 653.25 Td (and ) Tj ET Q q 0 0 0 rg BT 185.87 653.25 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 262.78 653.25 Td (activities.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.68 629.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 88.90 629.25 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 145.89 629.25 Td (contain ) Tj ET Q q 0 0 0 rg BT 178.45 629.25 Td (customary ) Tj ET Q q 0 0 0 rg BT 223.24 629.25 Td (early ) Tj ET Q q 0 0 0 rg BT 246.35 629.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 295.58 629.25 Td (provisions ) Tj ET Q q 0 0 0 rg BT 340.38 629.25 Td (following ) Tj ET Q q 0 0 0 rg BT 382.39 629.25 Td (material ) Tj ET Q q 0 0 0 rg BT 418.28 629.25 Td (breaches, ) Tj ET Q q 0 0 0 rg BT 458.88 629.25 Td (bankruptcy ) Tj ET Q q 0 0 0 rg BT 507.00 629.25 Td (or ) Tj ET Q q 0 0 0 rg BT 518.46 629.25 Td (product ) Tj ET Q q 0 0 0 rg BT 552.13 629.25 Td (safety ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (concerns. ) Tj ET Q q 0 0 0 rg BT 76.43 617.25 Td (The ) Tj ET Q q 0 0 0 rg BT 94.56 617.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 127.13 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 138.04 617.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 165.05 617.25 Td (required ) Tj ET Q q 0 0 0 rg BT 200.95 617.25 Td (for ) Tj ET Q q 0 0 0 rg BT 215.19 617.25 Td (early ) Tj ET Q q 0 0 0 rg BT 237.75 617.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 286.43 617.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 326.21 617.25 Td (ranges ) Tj ET Q q 0 0 0 rg BT 354.89 617.25 Td (from ) Tj ET Q q 0 0 0 rg BT 376.91 617.25 Td (immediately ) Tj ET Q q 0 0 0 rg BT 429.48 617.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 452.05 617.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 479.07 617.25 Td (to ) Tj ET Q q 0 0 0 rg BT 489.43 617.25 Td (180 ) Tj ET Q q 0 0 0 rg BT 507.01 617.25 Td (days ) Tj ET Q q 0 0 0 rg BT 527.92 617.25 Td (after ) Tj ET Q q 0 0 0 rg BT 548.81 617.25 Td (receipt ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.81 605.25 Td (notice. ) Tj ET Q q 0 0 0 rg BT 76.05 605.25 Td (T) Tj ET Q q 0 0 0 rg BT 81.46 605.25 Td (ermination ) Tj ET Q q 0 0 0 rg BT 127.27 605.25 Td (immediately ) Tj ET Q q 0 0 0 rg BT 179.74 605.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 202.22 605.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 229.14 605.25 Td (is ) Tj ET Q q 0 0 0 rg BT 238.29 605.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 277.98 605.25 Td (available ) Tj ET Q q 0 0 0 rg BT 316.55 605.25 Td (where ) Tj ET Q q 0 0 0 rg BT 343.47 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 358.17 605.25 Td (other ) Tj ET Q q 0 0 0 rg BT 381.20 605.25 Td (party ) Tj ET Q q 0 0 0 rg BT 404.23 605.25 Td (files ) Tj ET Q q 0 0 0 rg BT 423.93 605.25 Td (a ) Tj ET Q q 0 0 0 rg BT 430.85 605.25 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 471.66 605.25 Td (bankruptcy ) Tj ET Q q 0 0 0 rg BT 519.13 605.25 Td (petition ) Tj ET Q q 0 0 0 rg BT 552.17 605.25 Td (or ) Tj ET Q q 0 0 0 rg BT 562.98 605.25 Td (if ) Tj ET Q q 0 0 0 rg BT 571.58 605.25 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (material ) Tj ET Q q 0 0 0 rg BT 71.47 593.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 98.05 593.25 Td (issue ) Tj ET Q q 0 0 0 rg BT 120.76 593.25 Td (arises ) Tj ET Q q 0 0 0 rg BT 146.23 593.25 Td (with ) Tj ET Q q 0 0 0 rg BT 166.72 593.25 Td (a ) Tj ET Q q 0 0 0 rg BT 173.86 593.25 Td (product ) Tj ET Q q 0 0 0 rg BT 207.11 593.25 Td (such ) Tj ET Q q 0 0 0 rg BT 228.15 593.25 Td (that ) Tj ET Q q 0 0 0 rg BT 245.85 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 260.78 593.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 295.13 593.25 Td (risk/benefit ) Tj ET Q q 0 0 0 rg BT 343.38 593.25 Td (is ) Tj ET Q q 0 0 0 rg BT 352.76 593.25 Td (incompatible ) Tj ET Q q 0 0 0 rg BT 407.67 593.25 Td (with ) Tj ET Q q 0 0 0 rg BT 428.16 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 443.08 593.25 Td (welfare ) Tj ET Q q 0 0 0 rg BT 475.76 593.25 Td (of ) Tj ET Q q 0 0 0 rg BT 486.80 593.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 520.61 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 531.09 593.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 568.23 593.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 69.99 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 80.65 581.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 141.84 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 156.39 581.25 Td (product. ) Tj ET Q q 0 0 0 rg BT 191.60 581.25 Td (T) Tj ET Q q 0 0 0 rg BT 197.01 581.25 Td (ermination ) Tj ET Q q 0 0 0 rg BT 242.67 581.25 Td (with ) Tj ET Q q 0 0 0 rg BT 262.78 581.25 Td (a ) Tj ET Q q 0 0 0 rg BT 269.55 581.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 296.32 581.25 Td (period ) Tj ET Q q 0 0 0 rg BT 324.20 581.25 Td (is ) Tj ET Q q 0 0 0 rg BT 333.20 581.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 372.74 581.25 Td (available ) Tj ET Q q 0 0 0 rg BT 411.16 581.25 Td (where ) Tj ET Q q 0 0 0 rg BT 437.93 581.25 Td (an ) Tj ET Q q 0 0 0 rg BT 449.70 581.25 Td (involuntary ) Tj ET Q q 0 0 0 rg BT 498.14 581.25 Td (bankruptcy ) Tj ET Q q 0 0 0 rg BT 545.46 581.25 Td (petition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (has ) Tj ET Q q 0 0 0 rg BT 51.15 569.25 Td (been ) Tj ET Q q 0 0 0 rg BT 71.85 569.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 91.99 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 108.25 569.25 Td (has ) Tj ET Q q 0 0 0 rg BT 123.40 569.25 Td (not ) Tj ET Q q 0 0 0 rg BT 138.00 569.25 Td (been ) Tj ET Q q 0 0 0 rg BT 158.70 569.25 Td (dismissed ) Tj ET Q q 0 0 0 rg BT 199.97 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 210.12 569.25 Td (a ) Tj ET Q q 0 0 0 rg BT 216.38 569.25 Td (material ) Tj ET Q q 0 0 0 rg BT 250.96 569.25 Td (breach ) Tj ET Q q 0 0 0 rg BT 279.42 569.25 Td (by ) Tj ET Q q 0 0 0 rg BT 291.24 569.25 Td (a ) Tj ET Q q 0 0 0 rg BT 297.50 569.25 Td (party ) Tj ET Q q 0 0 0 rg BT 319.87 569.25 Td (has ) Tj ET Q q 0 0 0 rg BT 335.02 569.25 Td (occurred ) Tj ET Q q 0 0 0 rg BT 371.81 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 388.07 569.25 Td (not ) Tj ET Q q 0 0 0 rg BT 402.67 569.25 Td (been ) Tj ET Q q 0 0 0 rg BT 423.37 569.25 Td (cured. ) Tj ET Q q 0 0 0 rg BT 449.90 569.25 Td (Most ) Tj ET Q q 0 0 0 rg BT 472.28 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 482.43 569.25 Td (our ) Tj ET Q q 0 0 0 rg BT 497.58 569.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 530.49 569.25 Td (agreements ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (also ) Tj ET Q q 0 0 0 rg BT 55.84 557.25 Td (permit ) Tj ET Q q 0 0 0 rg BT 85.67 557.25 Td (us ) Tj ET Q q 0 0 0 rg BT 98.28 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 109.79 557.25 Td (terminate ) Tj ET Q q 0 0 0 rg BT 151.28 557.25 Td (without ) Tj ET Q q 0 0 0 rg BT 185.56 557.25 Td (cause, ) Tj ET Q q 0 0 0 rg BT 213.99 557.25 Td (which ) Tj ET Q q 0 0 0 rg BT 242.16 557.25 Td (is ) Tj ET Q q 0 0 0 rg BT 252.56 557.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 291.27 557.25 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 339.97 557.25 Td (with ) Tj ET Q q 0 0 0 rg BT 361.48 557.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 407.98 557.25 Td (advance ) Tj ET Q q 0 0 0 rg BT 444.46 557.25 Td (written ) Tj ET Q q 0 0 0 rg BT 476.51 557.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 504.67 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 522.84 557.25 Td (is ) Tj ET Q q 0 0 0 rg BT 533.23 557.25 Td (sometimes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 82.77 545.25 Td (only ) Tj ET Q q 0 0 0 rg BT 102.34 545.25 Td (after ) Tj ET Q q 0 0 0 rg BT 122.46 545.25 Td (a ) Tj ET Q q 0 0 0 rg BT 128.69 545.25 Td (specified ) Tj ET Q q 0 0 0 rg BT 166.58 545.25 Td (period ) Tj ET Q q 0 0 0 rg BT 193.92 545.25 Td (of ) Tj ET Q q 0 0 0 rg BT 204.05 545.25 Td (time ) Tj ET Q q 0 0 0 rg BT 223.62 545.25 Td (has ) Tj ET Q q 0 0 0 rg BT 238.75 545.25 Td (elapsed ) Tj ET Q q 0 0 0 rg BT 270.53 545.25 Td (after ) Tj ET Q q 0 0 0 rg BT 290.64 545.25 Td (the ) Tj ET Q q 0 0 0 rg BT 304.66 545.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 337.54 545.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 380.98 545.25 Td (is ) Tj ET Q q 0 0 0 rg BT 389.45 545.25 Td (signed. ) Tj ET Q q 0 0 0 rg BT 419.85 545.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 437.20 545.25 Td (alliances ) Tj ET Q q 0 0 0 rg BT 473.98 545.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 510.77 545.25 Td (do ) Tj ET Q q 0 0 0 rg BT 522.56 545.25 Td (not ) Tj ET Q q 0 0 0 rg BT 537.14 545.25 Td (otherwise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (contain ) Tj ET Q q 0 0 0 rg BT 67.93 533.25 Td (provisions ) Tj ET Q q 0 0 0 rg BT 112.10 533.25 Td (that ) Tj ET Q q 0 0 0 rg BT 129.60 533.25 Td (provide ) Tj ET Q q 0 0 0 rg BT 162.65 533.25 Td (the ) Tj ET Q q 0 0 0 rg BT 177.36 533.25 Td (other ) Tj ET Q q 0 0 0 rg BT 200.41 533.25 Td (party ) Tj ET Q q 0 0 0 rg BT 223.46 533.25 Td (the ) Tj ET Q q 0 0 0 rg BT 238.17 533.25 Td (right ) Tj ET Q q 0 0 0 rg BT 259.56 533.25 Td (to ) Tj ET Q q 0 0 0 rg BT 269.84 533.25 Td (terminate ) Tj ET Q q 0 0 0 rg BT 310.10 533.25 Td (the ) Tj ET Q q 0 0 0 rg BT 324.81 533.25 Td (alliance.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 509.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.58 509.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 89.08 509.25 Td (do ) Tj ET Q q 0 0 0 rg BT 101.59 509.25 Td (not ) Tj ET Q q 0 0 0 rg BT 116.88 509.25 Td (retain ) Tj ET Q q 0 0 0 rg BT 142.15 509.25 Td (any ) Tj ET Q q 0 0 0 rg BT 159.10 509.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 184.39 509.25 Td (to ) Tj ET Q q 0 0 0 rg BT 194.67 509.25 Td (another ) Tj ET Q q 0 0 0 rg BT 227.17 509.25 Td (party's ) Tj ET Q q 0 0 0 rg BT 255.92 509.25 Td (product ) Tj ET Q q 0 0 0 rg BT 288.97 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 299.81 509.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 346.74 509.25 Td (property ) Tj ET Q q 0 0 0 rg BT 383.13 509.25 Td (after ) Tj ET Q q 0 0 0 rg BT 403.95 509.25 Td (an ) Tj ET Q q 0 0 0 rg BT 415.90 509.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 449.50 509.25 Td (terminates. ) Tj ET Q q 0 0 0 rg BT 495.98 509.25 Td (The ) Tj ET Q q 0 0 0 rg BT 514.03 509.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 532.10 509.25 Td (of ) Tj ET Q q 0 0 0 rg BT 542.94 509.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 568.23 509.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (one ) Tj ET Q q 0 0 0 rg BT 53.41 497.25 Td (or ) Tj ET Q q 0 0 0 rg BT 64.71 497.25 Td (more ) Tj ET Q q 0 0 0 rg BT 88.23 497.25 Td (products ) Tj ET Q q 0 0 0 rg BT 125.63 497.25 Td (that ) Tj ET Q q 0 0 0 rg BT 143.60 497.25 Td (are ) Tj ET Q q 0 0 0 rg BT 158.78 497.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 198.95 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 216.36 497.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 236.00 497.25 Td (by ) Tj ET Q q 0 0 0 rg BT 248.97 497.25 Td (us ) Tj ET Q q 0 0 0 rg BT 260.83 497.25 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 298.24 497.25 Td (to ) Tj ET Q q 0 0 0 rg BT 308.99 497.25 Td (an ) Tj ET Q q 0 0 0 rg BT 321.40 497.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 355.46 497.25 Td (could ) Tj ET Q q 0 0 0 rg BT 380.64 497.25 Td (be ) Tj ET Q q 0 0 0 rg BT 393.05 497.25 Td (material ) Tj ET Q q 0 0 0 rg BT 428.78 497.25 Td (to ) Tj ET Q q 0 0 0 rg BT 439.53 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 455.83 497.25 Td (results ) Tj ET Q q 0 0 0 rg BT 484.91 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 496.21 497.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 540.83 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 558.24 497.25 Td (cash ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (flows ) Tj ET Q q 0 0 0 rg BT 60.30 485.25 Td (could ) Tj ET Q q 0 0 0 rg BT 84.59 485.25 Td (be ) Tj ET Q q 0 0 0 rg BT 96.10 485.25 Td (material ) Tj ET Q q 0 0 0 rg BT 130.94 485.25 Td (to ) Tj ET Q q 0 0 0 rg BT 140.79 485.25 Td (our ) Tj ET Q q 0 0 0 rg BT 156.20 485.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 193.25 485.25 Td (condition ) Tj ET Q q 0 0 0 rg BT 233.10 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 249.61 485.25 Td (liquidity) Tj ET Q q 0 0 0 rg BT 282.86 485.25 Td (. ) Tj ET Q q 0 0 0 rg BT 286.97 485.25 Td (As ) Tj ET Q q 0 0 0 rg BT 300.16 485.25 Td (is ) Tj ET Q q 0 0 0 rg BT 308.91 485.25 Td (customary ) Tj ET Q q 0 0 0 rg BT 352.64 485.25 Td (in ) Tj ET Q q 0 0 0 rg BT 362.49 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 376.78 485.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 439.93 485.25 Td (industry) Tj ET Q q 0 0 0 rg BT 472.06 485.25 Td (, ) Tj ET Q q 0 0 0 rg BT 476.64 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 490.93 485.25 Td (terms ) Tj ET Q q 0 0 0 rg BT 515.22 485.25 Td (of ) Tj ET Q q 0 0 0 rg BT 525.63 485.25 Td (our ) Tj ET Q q 0 0 0 rg BT 541.03 485.25 Td (alliances ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 75.70 473.25 Td (are ) Tj ET Q q 0 0 0 rg BT 90.41 473.25 Td (co-extensive ) Tj ET Q q 0 0 0 rg BT 143.44 473.25 Td (with ) Tj ET Q q 0 0 0 rg BT 163.72 473.25 Td (the ) Tj ET Q q 0 0 0 rg BT 178.44 473.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 224.82 473.25 Td (period ) Tj ET Q q 0 0 0 rg BT 252.87 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 269.80 473.25 Td (may ) Tj ET Q q 0 0 0 rg BT 289.52 473.25 Td (vary ) Tj ET Q q 0 0 0 rg BT 309.79 473.25 Td (on ) Tj ET Q q 0 0 0 rg BT 322.29 473.25 Td (a ) Tj ET Q q 0 0 0 rg BT 329.23 473.25 Td (country-by-country ) Tj ET Q q 0 0 0 rg BT 409.48 473.25 Td (basis.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.00 449.25 Td (most ) Tj ET Q q 0 0 0 rg BT 75.90 449.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 120.56 449.25 Td (alliances ) Tj ET Q q 0 0 0 rg BT 157.99 449.25 Td (for ) Tj ET Q q 0 0 0 rg BT 172.10 449.25 Td (both ) Tj ET Q q 0 0 0 rg BT 192.33 449.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 230.88 449.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 270.53 449.25 Td (products ) Tj ET Q q 0 0 0 rg BT 307.42 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 324.31 449.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 385.63 449.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 434.19 449.25 Td (are ) Tj ET Q q 0 0 0 rg BT 448.85 449.25 Td (described ) Tj ET Q q 0 0 0 rg BT 489.61 449.25 Td (below) Tj ET Q q 0 0 0 rg BT 513.40 449.25 Td (. ) Tj ET Q q 0 0 0 rg BT 518.35 449.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 543.01 449.25 Td (to ) Tj ET Q q 0 0 0 rg BT 553.24 449.25 Td (“Item ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 45.45 437.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 84.61 437.25 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.88 437.25 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 164.88 437.25 Td (. ) Tj ET Q q 0 0 0 rg BT 168.90 437.25 Td (Alliances” ) Tj ET Q q 0 0 0 rg BT 213.05 437.25 Td (for ) Tj ET Q q 0 0 0 rg BT 226.65 437.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 268.59 437.25 Td (information ) Tj ET Q q 0 0 0 rg BT 317.75 437.25 Td (on ) Tj ET Q q 0 0 0 rg BT 329.70 437.25 Td (these ) Tj ET Q q 0 0 0 rg BT 352.20 437.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 385.23 437.25 Td (agreements ) Tj ET Q q 0 0 0 rg BT 432.71 437.25 Td (as ) Tj ET Q q 0 0 0 rg BT 442.99 437.25 Td (well ) Tj ET Q q 0 0 0 rg BT 462.16 437.25 Td (as ) Tj ET Q q 0 0 0 rg BT 472.44 437.25 Td (other ) Tj ET Q q 0 0 0 rg BT 494.93 437.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 527.97 437.25 Td (agreements.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 417.9169921875 m 59.876953125 417.9169921875 l s q 0 0 0 rg BT 36.00 419.25 Td (Pfizer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 404.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.72 404.25 Td (and ) Tj ET Q q 0 0 0 rg BT 76.75 404.25 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 103.22 404.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 131.92 404.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 166.17 404.25 Td (and ) Tj ET Q q 0 0 0 rg BT 183.20 404.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 244.65 404.25 Td (Eliquis. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 278.08 404.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 301.79 404.25 Td (recognizes ) Tj ET Q q 0 0 0 rg BT 347.14 404.25 Td (net ) Tj ET Q q 0 0 0 rg BT 361.95 404.25 Td (product ) Tj ET Q q 0 0 0 rg BT 395.09 404.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 417.12 404.25 Td (in ) Tj ET Q q 0 0 0 rg BT 427.49 404.25 Td (most ) Tj ET Q q 0 0 0 rg BT 449.53 404.25 Td (markets. ) Tj ET Q q 0 0 0 rg BT 486.09 404.25 Td (W) Tj ET Q q 0 0 0 rg BT 494.73 404.25 Td (orldwide ) Tj ET Q q 0 0 0 rg BT 532.87 404.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 561.57 404.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 392.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 62.39 392.25 Td (are ) Tj ET Q q 0 0 0 rg BT 77.10 392.25 Td (shared ) Tj ET Q q 0 0 0 rg BT 105.70 392.25 Td (equally ) Tj ET Q q 0 0 0 rg BT 137.63 392.25 Td (except ) Tj ET Q q 0 0 0 rg BT 166.22 392.25 Td (in ) Tj ET Q q 0 0 0 rg BT 176.50 392.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 206.21 392.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 245.36 392.25 Td (where ) Tj ET Q q 0 0 0 rg BT 272.29 392.25 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 298.67 392.25 Td (commercializes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 363.91 392.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.25 392.25 Td ( ) Tj ET Q q 0 0 0 rg BT 394.75 392.25 Td (and ) Tj ET Q q 0 0 0 rg BT 411.68 392.25 Td (pays ) Tj ET Q q 0 0 0 rg BT 432.51 392.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 456.14 392.25 Td (a ) Tj ET Q q 0 0 0 rg BT 463.08 392.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 511.11 392.25 Td (fee.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 369.9169921875 m 64.330078125 369.9169921875 l s q 0 0 0 rg BT 36.00 371.25 Td (Otsuka) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 356.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.45 356.25 Td (and ) Tj ET Q q 0 0 0 rg BT 76.21 356.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 106.86 356.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 135.30 356.25 Td (promote ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 170.95 356.25 Td (Sprycel ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 203.26 356.25 Td (in ) Tj ET Q q 0 0 0 rg BT 213.36 356.25 Td (the ) Tj ET Q q 0 0 0 rg BT 227.90 356.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 248.01 356.25 Td (and ) Tj ET Q q 0 0 0 rg BT 264.77 356.25 Td (EU. ) Tj ET Q q 0 0 0 rg BT 282.93 356.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 306.38 356.25 Td (recognizes ) Tj ET Q q 0 0 0 rg BT 351.45 356.25 Td (net ) Tj ET Q q 0 0 0 rg BT 366.00 356.25 Td (product ) Tj ET Q q 0 0 0 rg BT 398.87 356.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 420.63 356.25 Td (and ) Tj ET Q q 0 0 0 rg BT 437.39 356.25 Td (a ) Tj ET Q q 0 0 0 rg BT 444.15 356.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 492.02 356.25 Td (fee ) Tj ET Q q 0 0 0 rg BT 506.55 356.25 Td (is ) Tj ET Q q 0 0 0 rg BT 515.54 356.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 535.08 356.25 Td (to ) Tj ET Q q 0 0 0 rg BT 545.18 356.25 Td (Otsuka. ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 333.9169921875 m 53.2216796875 333.9169921875 l s q 0 0 0 rg BT 36.00 335.25 Td (Ono) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 320.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 58.95 320.25 Td (has ) Tj ET Q q 0 0 0 rg BT 74.11 320.25 Td (the ) Tj ET Q q 0 0 0 rg BT 88.16 320.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 127.75 320.25 Td (right ) Tj ET Q q 0 0 0 rg BT 148.47 320.25 Td (to ) Tj ET Q q 0 0 0 rg BT 158.08 320.25 Td (develop, ) Tj ET Q q 0 0 0 rg BT 194.06 320.25 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 245.87 320.25 Td (and ) Tj ET Q q 0 0 0 rg BT 262.13 320.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 322.82 320.25 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.25 320.25 Td ( ) Tj ET Q q 0 0 0 rg BT 354.08 320.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 398.68 320.25 Td (except ) Tj ET Q q 0 0 0 rg BT 426.61 320.25 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 453.71 320.25 Td (South ) Tj ET Q q 0 0 0 rg BT 478.88 320.25 Td (Korea ) Tj ET Q q 0 0 0 rg BT 505.13 320.25 Td (and ) Tj ET Q q 0 0 0 rg BT 521.27 320.25 Td (T) Tj ET Q q 0 0 0 rg BT 526.68 320.25 Td (aiwan. ) Tj ET Q q 0 0 0 rg BT 554.89 320.25 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 308.25 Td (recognizes ) Tj ET Q q 0 0 0 rg BT 81.68 308.25 Td (net ) Tj ET Q q 0 0 0 rg BT 96.82 308.25 Td (product ) Tj ET Q q 0 0 0 rg BT 130.28 308.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 152.65 308.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.01 308.25 Td (pays ) Tj ET Q q 0 0 0 rg BT 191.26 308.25 Td (Ono ) Tj ET Q q 0 0 0 rg BT 211.40 308.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 248.76 308.25 Td (of ) Tj ET Q q 0 0 0 rg BT 260.01 308.25 Td (4% ) Tj ET Q q 0 0 0 rg BT 276.26 308.25 Td (in ) Tj ET Q q 0 0 0 rg BT 286.96 308.25 Td (North ) Tj ET Q q 0 0 0 rg BT 312.57 308.25 Td (America ) Tj ET Q q 0 0 0 rg BT 349.92 308.25 Td (and ) Tj ET Q q 0 0 0 rg BT 367.28 308.25 Td (15% ) Tj ET Q q 0 0 0 rg BT 388.53 308.25 Td (in ) Tj ET Q q 0 0 0 rg BT 399.23 308.25 Td (all ) Tj ET Q q 0 0 0 rg BT 412.15 308.25 Td (other ) Tj ET Q q 0 0 0 rg BT 435.62 308.25 Td (applicable ) Tj ET Q q 0 0 0 rg BT 479.63 308.25 Td (territories ) Tj ET Q q 0 0 0 rg BT 521.42 308.25 Td (excluding ) Tj ET Q q 0 0 0 rg BT 563.78 308.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 296.25 Td (three ) Tj ET Q q 0 0 0 rg BT 58.49 296.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 97.64 296.25 Td (listed ) Tj ET Q q 0 0 0 rg BT 121.81 296.25 Td (above, ) Tj ET Q q 0 0 0 rg BT 150.68 296.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 181.51 296.25 Td (to ) Tj ET Q q 0 0 0 rg BT 191.79 296.25 Td (customary ) Tj ET Q q 0 0 0 rg BT 235.94 296.25 Td (adjustments.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 272.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.93 272.25 Td (and ) Tj ET Q q 0 0 0 rg BT 77.17 272.25 Td (Ono ) Tj ET Q q 0 0 0 rg BT 97.20 272.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 126.12 272.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 160.58 272.25 Td (and ) Tj ET Q q 0 0 0 rg BT 177.82 272.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 239.48 272.25 Td (Opdivo, ) Tj ET Q q 0 0 0 rg BT 274.22 272.25 Td (Y) Tj ET Q q 0 0 0 rg BT 278.87 272.25 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.07 272.25 Td ( ) Tj ET Q q 0 0 0 rg BT 303.88 272.25 Td (and ) Tj ET Q q 0 0 0 rg BT 321.12 272.25 Td (several ) Tj ET Q q 0 0 0 rg BT 352.24 272.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 376.17 272.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 437.85 272.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 486.77 272.25 Td (in ) Tj ET Q q 0 0 0 rg BT 497.35 272.25 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 525.42 272.25 Td (South ) Tj ET Q q 0 0 0 rg BT 551.57 272.25 Td (Korea ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 260.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.58 260.25 Td (T) Tj ET Q q 0 0 0 rg BT 57.99 260.25 Td (aiwan. ) Tj ET Q q 0 0 0 rg BT 86.69 260.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 110.12 260.25 Td (is ) Tj ET Q q 0 0 0 rg BT 119.10 260.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 166.97 260.25 Td (for ) Tj ET Q q 0 0 0 rg BT 180.94 260.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 209.92 260.25 Td (of ) Tj ET Q q 0 0 0 rg BT 220.57 260.25 Td (the ) Tj ET Q q 0 0 0 rg BT 235.10 260.25 Td (products. ) Tj ET Q q 0 0 0 rg BT 274.35 260.25 Td (Profits, ) Tj ET Q q 0 0 0 rg BT 305.83 260.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 332.04 260.25 Td (and ) Tj ET Q q 0 0 0 rg BT 348.79 260.25 Td (development ) Tj ET Q q 0 0 0 rg BT 402.75 260.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 425.07 260.25 Td (are ) Tj ET Q q 0 0 0 rg BT 439.59 260.25 Td (shared ) Tj ET Q q 0 0 0 rg BT 468.00 260.25 Td (equally ) Tj ET Q q 0 0 0 rg BT 499.75 260.25 Td (for ) Tj ET Q q 0 0 0 rg BT 513.72 260.25 Td (all ) Tj ET Q q 0 0 0 rg BT 526.03 260.25 Td (combination ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 248.25 Td (therapies ) Tj ET Q q 0 0 0 rg BT 75.64 248.25 Td (involving ) Tj ET Q q 0 0 0 rg BT 117.52 248.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 167.17 248.25 Td (of ) Tj ET Q q 0 0 0 rg BT 179.04 248.25 Td (both ) Tj ET Q q 0 0 0 rg BT 200.37 248.25 Td (parties. ) Tj ET Q q 0 0 0 rg BT 233.06 248.25 Td (Otherwise, ) Tj ET Q q 0 0 0 rg BT 280.21 248.25 Td (sharing ) Tj ET Q q 0 0 0 rg BT 313.19 248.25 Td (is ) Tj ET Q q 0 0 0 rg BT 323.40 248.25 Td (80% ) Tj ET Q q 0 0 0 rg BT 345.28 248.25 Td (and ) Tj ET Q q 0 0 0 rg BT 363.26 248.25 Td (20% ) Tj ET Q q 0 0 0 rg BT 385.13 248.25 Td (for ) Tj ET Q q 0 0 0 rg BT 400.34 248.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 439.98 248.25 Td (involving ) Tj ET Q q 0 0 0 rg BT 481.86 248.25 Td (only ) Tj ET Q q 0 0 0 rg BT 503.18 248.25 Td (one ) Tj ET Q q 0 0 0 rg BT 521.16 248.25 Td (of ) Tj ET Q q 0 0 0 rg BT 533.04 248.25 Td (the ) Tj ET Q q 0 0 0 rg BT 548.80 248.25 Td (party’) Tj ET Q q 0 0 0 rg BT 572.12 248.25 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 236.25 Td (compounds. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 212.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.36 212.25 Td (and ) Tj ET Q q 0 0 0 rg BT 76.03 212.25 Td (Ono ) Tj ET Q q 0 0 0 rg BT 95.48 212.25 Td (also ) Tj ET Q q 0 0 0 rg BT 113.82 212.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 142.17 212.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 176.06 212.25 Td (and ) Tj ET Q q 0 0 0 rg BT 192.73 212.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 253.81 212.25 Td (Or) Tj ET Q q 0 0 0 rg BT 264.56 212.25 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 286.21 212.25 Td ( ) Tj ET Q q 0 0 0 rg BT 288.44 212.25 Td (in ) Tj ET Q q 0 0 0 rg BT 298.46 212.25 Td (Japan. ) Tj ET Q q 0 0 0 rg BT 325.96 212.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 349.31 212.25 Td (is ) Tj ET Q q 0 0 0 rg BT 358.22 212.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 406.00 212.25 Td (for ) Tj ET Q q 0 0 0 rg BT 419.89 212.25 Td (the ) Tj ET Q q 0 0 0 rg BT 434.34 212.25 Td (order ) Tj ET Q q 0 0 0 rg BT 457.67 212.25 Td (fulfillment ) Tj ET Q q 0 0 0 rg BT 502.67 212.25 Td (and ) Tj ET Q q 0 0 0 rg BT 519.34 212.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 567.69 212.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 200.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.82 200.25 Td (intravenous ) Tj ET Q q 0 0 0 rg BT 102.07 200.25 Td (formulation ) Tj ET Q q 0 0 0 rg BT 152.88 200.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.92 200.25 Td (Ono ) Tj ET Q q 0 0 0 rg BT 191.74 200.25 Td (is ) Tj ET Q q 0 0 0 rg BT 202.01 200.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 251.16 200.25 Td (for ) Tj ET Q q 0 0 0 rg BT 266.42 200.25 Td (the ) Tj ET Q q 0 0 0 rg BT 282.24 200.25 Td (subcutaneous ) Tj ET Q q 0 0 0 rg BT 339.72 200.25 Td (formulation. ) Tj ET Q q 0 0 0 rg BT 393.03 200.25 Td (Both ) Tj ET Q q 0 0 0 rg BT 416.08 200.25 Td (formulations ) Tj ET Q q 0 0 0 rg BT 470.78 200.25 Td (are ) Tj ET Q q 0 0 0 rg BT 486.59 200.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 516.30 200.25 Td (promoted ) Tj ET Q q 0 0 0 rg BT 558.23 200.25 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 188.25 Td (assigned ) Tj ET Q q 0 0 0 rg BT 73.14 188.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 112.50 188.25 Td (accounts ) Tj ET Q q 0 0 0 rg BT 150.19 188.25 Td (and ) Tj ET Q q 0 0 0 rg BT 167.33 188.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 191.16 188.25 Td (is ) Tj ET Q q 0 0 0 rg BT 200.54 188.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 248.79 188.25 Td (for ) Tj ET Q q 0 0 0 rg BT 263.15 188.25 Td (the ) Tj ET Q q 0 0 0 rg BT 278.07 188.25 Td (product ) Tj ET Q q 0 0 0 rg BT 311.32 188.25 Td (supply) Tj ET Q q 0 0 0 rg BT 337.34 188.25 Td (. ) Tj ET Q q 0 0 0 rg BT 341.95 188.25 Td (A) Tj ET Q q 0 0 0 rg BT 348.62 188.25 Td ( ) Tj ET Q q 0 0 0 rg BT 351.32 188.25 Td (co-promotion ) Tj ET Q q 0 0 0 rg BT 408.46 188.25 Td (fee ) Tj ET Q q 0 0 0 rg BT 423.37 188.25 Td (of ) Tj ET Q q 0 0 0 rg BT 434.41 188.25 Td (60% ) Tj ET Q q 0 0 0 rg BT 455.44 188.25 Td (is ) Tj ET Q q 0 0 0 rg BT 464.81 188.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 484.74 188.25 Td (when ) Tj ET Q q 0 0 0 rg BT 509.10 188.25 Td (a ) Tj ET Q q 0 0 0 rg BT 516.24 188.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 534.49 188.25 Td (is ) Tj ET Q q 0 0 0 rg BT 543.87 188.25 Td (made ) Tj ET Q q 0 0 0 rg BT 568.23 188.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 176.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 176.25 Td (other ) Tj ET Q q 0 0 0 rg BT 73.76 176.25 Td (party’) Tj ET Q q 0 0 0 rg BT 97.09 176.25 Td (s ) Tj ET Q q 0 0 0 rg BT 103.48 176.25 Td (assigned ) Tj ET Q q 0 0 0 rg BT 140.42 176.25 Td (customer) Tj ET Q q 0 0 0 rg BT 176.52 176.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 150.9169921875 m 67.0595703125 150.9169921875 l s q 0 0 0 rg BT 36.00 152.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 59.84 152.25 Td (ie) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.54 137.25 Td (and ) Tj ET Q q 0 0 0 rg BT 77.64 137.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 101.48 137.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 112.11 137.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 141.64 137.25 Td (develop ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 176.71 137.25 Td (Empliciti.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 215.87 137.25 Td ( ) Tj ET Q q 0 0 0 rg BT 218.54 137.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 242.38 137.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 253.01 137.25 Td (funds ) Tj ET Q q 0 0 0 rg BT 278.65 137.25 Td (20% ) Tj ET Q q 0 0 0 rg BT 300.39 137.25 Td (of ) Tj ET Q q 0 0 0 rg BT 312.14 137.25 Td (global ) Tj ET Q q 0 0 0 rg BT 340.55 137.25 Td (development ) Tj ET Q q 0 0 0 rg BT 395.62 137.25 Td (costs. ) Tj ET Q q 0 0 0 rg BT 421.53 137.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 446.07 137.25 Td (is ) Tj ET Q q 0 0 0 rg BT 456.15 137.25 Td (solely ) Tj ET Q q 0 0 0 rg BT 483.46 137.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 532.42 137.25 Td (for ) Tj ET Q q 0 0 0 rg BT 547.50 137.25 Td (supply) Tj ET Q q 0 0 0 rg BT 573.52 137.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 84.62 125.25 Td (and ) Tj ET Q q 0 0 0 rg BT 101.57 125.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 123.52 125.25 Td (and ) Tj ET Q q 0 0 0 rg BT 140.46 125.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 183.51 125.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 222.12 125.25 Td (and ) Tj ET Q q 0 0 0 rg BT 239.07 125.25 Td (recognizes ) Tj ET Q q 0 0 0 rg BT 284.33 125.25 Td (net ) Tj ET Q q 0 0 0 rg BT 299.06 125.25 Td (product ) Tj ET Q q 0 0 0 rg BT 332.11 125.25 Td (sales. ) Tj ET Q q 0 0 0 rg BT 356.01 125.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 379.85 125.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 389.58 125.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 417.07 125.25 Td (30% ) Tj ET Q q 0 0 0 rg BT 437.91 125.25 Td (of ) Tj ET Q q 0 0 0 rg BT 448.75 125.25 Td (all ) Tj ET Q q 0 0 0 rg BT 461.26 125.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 489.87 125.25 Td (and ) Tj ET Q q 0 0 0 rg BT 506.82 125.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 533.22 125.25 Td (in ) Tj ET Q q 0 0 0 rg BT 543.51 125.25 Td (the ) Tj ET Q q 0 0 0 rg BT 558.23 125.25 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 113.25 Td (is ) Tj ET Q q 0 0 0 rg BT 62.11 113.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 81.83 113.25 Td (tiered ) Tj ET Q q 0 0 0 rg BT 107.09 113.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 144.02 113.25 Td (outside ) Tj ET Q q 0 0 0 rg BT 175.41 113.25 Td (of ) Tj ET Q q 0 0 0 rg BT 186.24 113.25 Td (the ) Tj ET Q q 0 0 0 rg BT 200.96 113.25 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 93.9169921875 m 62.6552734375 93.9169921875 l s q 0 0 0 rg BT 36.00 95.25 Td (Gilead) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 80.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.24 80.25 Td (and ) Tj ET Q q 0 0 0 rg BT 77.80 80.25 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 107.57 80.25 Td (formed ) Tj ET Q q 0 0 0 rg BT 139.56 80.25 Td (a ) Tj ET Q q 0 0 0 rg BT 147.12 80.25 Td (joint ) Tj ET Q q 0 0 0 rg BT 168.57 80.25 Td (venture ) Tj ET Q q 0 0 0 rg BT 201.68 80.25 Td (to ) Tj ET Q q 0 0 0 rg BT 212.57 80.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 247.35 80.25 Td (and ) Tj ET Q q 0 0 0 rg BT 264.90 80.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 326.87 80.25 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.21 80.25 Td ( ) Tj ET Q q 0 0 0 rg BT 363.32 80.25 Td (in ) Tj ET Q q 0 0 0 rg BT 374.22 80.25 Td (the ) Tj ET Q q 0 0 0 rg BT 389.55 80.25 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 412.96 80.25 Td (Canada ) Tj ET Q q 0 0 0 rg BT 446.06 80.25 Td (and ) Tj ET Q q 0 0 0 rg BT 463.61 80.25 Td (in ) Tj ET Q q 0 0 0 rg BT 474.51 80.25 Td (Europe. ) Tj ET Q q 0 0 0 rg BT 509.01 80.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 533.25 80.25 Td (recognizes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 68.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 69.59 68.25 Td (revenue ) Tj ET Q q 0 0 0 rg BT 103.73 68.25 Td (for ) Tj ET Q q 0 0 0 rg BT 117.89 68.25 Td (the ) Tj ET Q q 0 0 0 rg BT 132.61 68.25 Td (bulk ) Tj ET Q q 0 0 0 rg BT 152.89 68.25 Td (efavirenz ) Tj ET Q q 0 0 0 rg BT 192.58 68.25 Td (component ) Tj ET Q q 0 0 0 rg BT 239.52 68.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 250.35 68.25 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 283.68 68.25 Td ( ) Tj ET Q q 0 0 0 rg BT 286.18 68.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 308.68 68.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 330.62 68.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 341.45 68.25 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 374.78 68.25 Td ( ) Tj ET Q q 0 0 0 rg BT 377.28 68.25 Td (to ) Tj ET Q q 0 0 0 rg BT 387.56 68.25 Td (third-party ) Tj ET Q q 0 0 0 rg BT 432.83 68.25 Td (customers. ) Tj ET Q endstream endobj 25 0 obj <> endobj 26 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (In ) Tj ET Q q 0 0 0 rg BT 45.98 749.10 Td (December ) Tj ET Q q 0 0 0 rg BT 88.72 749.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 112.87 749.10 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 141.18 749.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 185.59 749.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 214.06 749.10 Td (participation ) Tj ET Q q 0 0 0 rg BT 266.24 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 275.67 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 289.54 749.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 308.98 749.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 328.97 749.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 360.60 749.10 Td (which ) Tj ET Q q 0 0 0 rg BT 386.69 749.10 Td (included ) Tj ET Q q 0 0 0 rg BT 422.78 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 436.65 749.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 456.08 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 472.17 749.10 Td (Canada ) Tj ET Q q 0 0 0 rg BT 503.81 749.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 537.12 749.10 Td (following ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.55 737.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 79.53 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 90.19 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 96.96 737.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 128.72 737.10 Td (version ) Tj ET Q q 0 0 0 rg BT 160.49 737.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 171.15 737.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 200.03 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 202.36 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 212.47 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 227.02 737.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 247.13 737.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 270.59 737.10 Td (will ) Tj ET Q q 0 0 0 rg BT 288.48 737.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 319.67 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 326.44 737.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 348.21 737.10 Td (based ) Tj ET Q q 0 0 0 rg BT 373.31 737.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 387.84 737.10 Td (from ) Tj ET Q q 0 0 0 rg BT 409.61 737.10 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 438.60 737.10 Td (on ) Tj ET Q q 0 0 0 rg BT 450.93 737.10 Td (net ) Tj ET Q q 0 0 0 rg BT 465.48 737.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 487.24 737.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 497.91 737.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 531.24 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 533.57 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 543.68 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 558.23 737.10 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 725.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 71.28 725.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 93.78 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 110.72 725.10 Td (2020.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 702.7669921875 m 159.6962890625 702.7669921875 l s q 0 0 0 rg BT 36.00 704.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.83 704.10 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 103.04 704.10 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 689.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.90 689.10 Td (have ) Tj ET Q q 0 0 0 rg BT 73.60 689.10 Td (other ) Tj ET Q q 0 0 0 rg BT 96.96 689.10 Td (in-licensing ) Tj ET Q q 0 0 0 rg BT 147.00 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 164.26 689.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 219.29 689.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 275.97 689.10 Td (without ) Tj ET Q q 0 0 0 rg BT 309.35 689.10 Td (active ) Tj ET Q q 0 0 0 rg BT 336.04 689.10 Td (participation ) Tj ET Q q 0 0 0 rg BT 389.40 689.10 Td (by ) Tj ET Q q 0 0 0 rg BT 402.22 689.10 Td (both ) Tj ET Q q 0 0 0 rg BT 422.82 689.10 Td (parties, ) Tj ET Q q 0 0 0 rg BT 454.80 689.10 Td (including ) Tj ET Q q 0 0 0 rg BT 495.40 689.10 Td (those ) Tj ET Q q 0 0 0 rg BT 519.33 689.10 Td (obtained ) Tj ET Q q 0 0 0 rg BT 556.58 689.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 51.69 677.10 Td (acquisitions. ) Tj ET Q q 0 0 0 rg BT 104.15 677.10 Td (W) Tj ET Q q 0 0 0 rg BT 112.78 677.10 Td (e ) Tj ET Q q 0 0 0 rg BT 119.58 677.10 Td (are ) Tj ET Q q 0 0 0 rg BT 134.14 677.10 Td (typically ) Tj ET Q q 0 0 0 rg BT 171.49 677.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 203.83 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 213.97 677.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 245.19 677.10 Td (or ) Tj ET Q q 0 0 0 rg BT 255.87 677.10 Td (obligated ) Tj ET Q q 0 0 0 rg BT 295.44 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 305.57 677.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 322.37 677.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 366.94 677.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 408.17 677.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 448.85 677.10 Td (as ) Tj ET Q q 0 0 0 rg BT 459.54 677.10 Td (well ) Tj ET Q q 0 0 0 rg BT 479.11 677.10 Td (as ) Tj ET Q q 0 0 0 rg BT 489.80 677.10 Td (royalties, ) Tj ET Q q 0 0 0 rg BT 529.09 677.10 Td (if ) Tj ET Q q 0 0 0 rg BT 537.55 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 554.35 677.10 Td (when ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 665.10 Td (products ) Tj ET Q q 0 0 0 rg BT 87.66 665.10 Td (are ) Tj ET Q q 0 0 0 rg BT 102.36 665.10 Td (commercialized.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (Marketing, Distribution and Customers) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 617.10 Td (e ) Tj ET Q q 0 0 0 rg BT 50.93 617.10 Td (promote ) Tj ET Q q 0 0 0 rg BT 86.11 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.18 617.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 147.57 617.10 Td (use ) Tj ET Q q 0 0 0 rg BT 162.76 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 172.94 617.10 Td (our ) Tj ET Q q 0 0 0 rg BT 188.13 617.10 Td (products ) Tj ET Q q 0 0 0 rg BT 224.42 617.10 Td (directly ) Tj ET Q q 0 0 0 rg BT 256.82 617.10 Td (to ) Tj ET Q q 0 0 0 rg BT 266.45 617.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 309.39 617.10 Td (professionals ) Tj ET Q q 0 0 0 rg BT 364.01 617.10 Td (and ) Tj ET Q q 0 0 0 rg BT 380.31 617.10 Td (or) Tj ET Q q 0 0 0 rg BT 388.46 617.10 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 435.85 617.10 Td (such ) Tj ET Q q 0 0 0 rg BT 456.04 617.10 Td (as ) Tj ET Q q 0 0 0 rg BT 466.22 617.10 Td (doctors, ) Tj ET Q q 0 0 0 rg BT 500.02 617.10 Td (nurse ) Tj ET Q q 0 0 0 rg BT 523.53 617.10 Td (practitioners, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (physician ) Tj ET Q q 0 0 0 rg BT 76.88 605.10 Td (assistants, ) Tj ET Q q 0 0 0 rg BT 119.70 605.10 Td (pharmacists, ) Tj ET Q q 0 0 0 rg BT 172.52 605.10 Td (technologists, ) Tj ET Q q 0 0 0 rg BT 230.34 605.10 Td (hospitals, ) Tj ET Q q 0 0 0 rg BT 270.95 605.10 Td (PBMs ) Tj ET Q q 0 0 0 rg BT 298.51 605.10 Td (and ) Tj ET Q q 0 0 0 rg BT 315.50 605.10 Td (MCOs. ) Tj ET Q q 0 0 0 rg BT 347.04 605.10 Td (W) Tj ET Q q 0 0 0 rg BT 355.68 605.10 Td (e ) Tj ET Q q 0 0 0 rg BT 362.67 605.10 Td (also ) Tj ET Q q 0 0 0 rg BT 381.33 605.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 414.43 605.10 Td (information ) Tj ET Q q 0 0 0 rg BT 464.19 605.10 Td (about ) Tj ET Q q 0 0 0 rg BT 488.95 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 503.72 605.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 551.80 605.10 Td (use ) Tj ET Q q 0 0 0 rg BT 567.68 605.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (our ) Tj ET Q q 0 0 0 rg BT 50.82 593.10 Td (products ) Tj ET Q q 0 0 0 rg BT 86.75 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 96.01 593.10 Td (consumers ) Tj ET Q q 0 0 0 rg BT 140.27 593.10 Td (in ) Tj ET Q q 0 0 0 rg BT 149.54 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 163.24 593.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 182.51 593.10 Td (through ) Tj ET Q q 0 0 0 rg BT 215.11 593.10 Td (direct-to-consumer ) Tj ET Q q 0 0 0 rg BT 292.68 593.10 Td (print, ) Tj ET Q q 0 0 0 rg BT 315.55 593.10 Td (radio, ) Tj ET Q q 0 0 0 rg BT 340.09 593.10 Td (television ) Tj ET Q q 0 0 0 rg BT 380.46 593.10 Td (and ) Tj ET Q q 0 0 0 rg BT 396.38 593.10 Td (digital ) Tj ET Q q 0 0 0 rg BT 423.42 593.10 Td (advertising ) Tj ET Q q 0 0 0 rg BT 469.34 593.10 Td (and ) Tj ET Q q 0 0 0 rg BT 485.27 593.10 Td (promotion. ) Tj ET Q q 0 0 0 rg BT 530.92 593.10 Td (In ) Tj ET Q q 0 0 0 rg BT 540.74 593.10 Td (addition, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (we ) Tj ET Q q 0 0 0 rg BT 50.34 581.10 Td (sponsor ) Tj ET Q q 0 0 0 rg BT 84.14 581.10 Td (general ) Tj ET Q q 0 0 0 rg BT 116.25 581.10 Td (advertising ) Tj ET Q q 0 0 0 rg BT 163.37 581.10 Td (to ) Tj ET Q q 0 0 0 rg BT 173.83 581.10 Td (educate ) Tj ET Q q 0 0 0 rg BT 207.05 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 221.95 581.10 Td (public ) Tj ET Q q 0 0 0 rg BT 249.63 581.10 Td (about ) Tj ET Q q 0 0 0 rg BT 274.53 581.10 Td (our ) Tj ET Q q 0 0 0 rg BT 290.55 581.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 335.44 581.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 369.78 581.10 Td (research ) Tj ET Q q 0 0 0 rg BT 405.77 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 422.89 581.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 463.33 581.10 Td (mission. ) Tj ET Q q 0 0 0 rg BT 499.63 581.10 Td (For ) Tj ET Q q 0 0 0 rg BT 516.21 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 523.33 581.10 Td (discussion ) Tj ET Q q 0 0 0 rg BT 567.69 581.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 569.10 Td (regulation ) Tj ET Q q 0 0 0 rg BT 93.76 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 104.59 569.10 Td (promotion ) Tj ET Q q 0 0 0 rg BT 148.75 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 165.69 569.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 208.73 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 219.56 569.10 Td (pharmaceuticals, ) Tj ET Q q 0 0 0 rg BT 289.53 569.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 310.90 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 321.18 569.10 Td (“—Government ) Tj ET Q q 0 0 0 rg BT 388.10 569.10 Td (Regulation”.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (Through ) Tj ET Q q 0 0 0 rg BT 73.46 545.10 Td (our ) Tj ET Q q 0 0 0 rg BT 89.81 545.10 Td (field ) Tj ET Q q 0 0 0 rg BT 111.15 545.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 133.61 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 151.07 545.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 185.74 545.10 Td (or) Tj ET Q q 0 0 0 rg BT 193.88 545.10 Td (ganizations, ) Tj ET Q q 0 0 0 rg BT 244.95 545.10 Td (we ) Tj ET Q q 0 0 0 rg BT 259.63 545.10 Td (explain ) Tj ET Q q 0 0 0 rg BT 292.08 545.10 Td (the ) Tj ET Q q 0 0 0 rg BT 307.31 545.10 Td (risks ) Tj ET Q q 0 0 0 rg BT 329.22 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 346.68 545.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 381.36 545.10 Td (of ) Tj ET Q q 0 0 0 rg BT 392.71 545.10 Td (the ) Tj ET Q q 0 0 0 rg BT 407.94 545.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 448.17 545.10 Td (uses ) Tj ET Q q 0 0 0 rg BT 468.41 545.10 Td (of ) Tj ET Q q 0 0 0 rg BT 479.76 545.10 Td (our ) Tj ET Q q 0 0 0 rg BT 496.11 545.10 Td (products ) Tj ET Q q 0 0 0 rg BT 533.56 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 544.36 545.10 Td (medical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (professionals. ) Tj ET Q q 0 0 0 rg BT 94.35 533.10 Td (W) Tj ET Q q 0 0 0 rg BT 102.99 533.10 Td (e ) Tj ET Q q 0 0 0 rg BT 110.75 533.10 Td (work ) Tj ET Q q 0 0 0 rg BT 134.62 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 145.73 533.10 Td (gain ) Tj ET Q q 0 0 0 rg BT 166.27 533.10 Td (access ) Tj ET Q q 0 0 0 rg BT 195.13 533.10 Td (for ) Tj ET Q q 0 0 0 rg BT 210.11 533.10 Td (our ) Tj ET Q q 0 0 0 rg BT 226.76 533.10 Td (products ) Tj ET Q q 0 0 0 rg BT 264.52 533.10 Td (on ) Tj ET Q q 0 0 0 rg BT 277.84 533.10 Td (formularies ) Tj ET Q q 0 0 0 rg BT 327.26 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 345.02 533.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 408.33 533.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 432.76 533.10 Td (\(lists ) Tj ET Q q 0 0 0 rg BT 455.53 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 467.18 533.10 Td (recommended ) Tj ET Q q 0 0 0 rg BT 527.14 533.10 Td (or ) Tj ET Q q 0 0 0 rg BT 538.80 533.10 Td (approved ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 79.47 521.10 Td (and ) Tj ET Q q 0 0 0 rg BT 96.83 521.10 Td (other ) Tj ET Q q 0 0 0 rg BT 120.30 521.10 Td (products\), ) Tj ET Q q 0 0 0 rg BT 163.50 521.10 Td (including ) Tj ET Q q 0 0 0 rg BT 204.19 521.10 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 244.87 521.10 Td (Part ) Tj ET Q q 0 0 0 rg BT 263.91 521.10 Td (D ) Tj ET Q q 0 0 0 rg BT 274.05 521.10 Td (plans, ) Tj ET Q q 0 0 0 rg BT 300.58 521.10 Td (by ) Tj ET Q q 0 0 0 rg BT 313.51 521.10 Td (providing ) Tj ET Q q 0 0 0 rg BT 355.32 521.10 Td (information ) Tj ET Q q 0 0 0 rg BT 405.46 521.10 Td (about ) Tj ET Q q 0 0 0 rg BT 430.60 521.10 Td (the ) Tj ET Q q 0 0 0 rg BT 445.74 521.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 478.09 521.10 Td (profiles ) Tj ET Q q 0 0 0 rg BT 511.57 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 522.82 521.10 Td (our ) Tj ET Q q 0 0 0 rg BT 539.08 521.10 Td (products. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.60 509.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 98.19 509.10 Td (and ) Tj ET Q q 0 0 0 rg BT 115.68 509.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 138.17 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 149.55 509.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 200.36 509.10 Td (pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 268.38 509.10 Td (is ) Tj ET Q q 0 0 0 rg BT 278.09 509.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 309.47 509.10 Td (to ) Tj ET Q q 0 0 0 rg BT 320.30 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.57 509.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 375.82 509.10 Td (uses ) Tj ET Q q 0 0 0 rg BT 396.10 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 407.47 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.74 509.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 464.10 509.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 500.20 509.10 Td (but ) Tj ET Q q 0 0 0 rg BT 516.02 509.10 Td (we ) Tj ET Q q 0 0 0 rg BT 530.73 509.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 568.22 509.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 70.26 497.10 Td (scientific ) Tj ET Q q 0 0 0 rg BT 109.51 497.10 Td (data ) Tj ET Q q 0 0 0 rg BT 128.77 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 145.81 497.10 Td (other ) Tj ET Q q 0 0 0 rg BT 168.95 497.10 Td (information ) Tj ET Q q 0 0 0 rg BT 218.77 497.10 Td (about ) Tj ET Q q 0 0 0 rg BT 243.59 497.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 281.18 497.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 323.77 497.10 Td (uses ) Tj ET Q q 0 0 0 rg BT 343.59 497.10 Td (of ) Tj ET Q q 0 0 0 rg BT 354.52 497.10 Td (our ) Tj ET Q q 0 0 0 rg BT 370.46 497.10 Td (products ) Tj ET Q q 0 0 0 rg BT 407.50 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 424.54 497.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 457.68 497.10 Td (such ) Tj ET Q q 0 0 0 rg BT 478.62 497.10 Td (information ) Tj ET Q q 0 0 0 rg BT 528.43 497.10 Td (as ) Tj ET Q q 0 0 0 rg BT 539.36 497.10 Td (scientific ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 76.67 485.10 Td (at ) Tj ET Q q 0 0 0 rg BT 86.79 485.10 Td (scientific ) Tj ET Q q 0 0 0 rg BT 126.36 485.10 Td (congresses ) Tj ET Q q 0 0 0 rg BT 172.59 485.10 Td (or ) Tj ET Q q 0 0 0 rg BT 183.83 485.10 Td (we ) Tj ET Q q 0 0 0 rg BT 198.40 485.10 Td (share ) Tj ET Q q 0 0 0 rg BT 222.41 485.10 Td (information ) Tj ET Q q 0 0 0 rg BT 272.54 485.10 Td (about ) Tj ET Q q 0 0 0 rg BT 297.66 485.10 Td (our ) Tj ET Q q 0 0 0 rg BT 313.91 485.10 Td (products ) Tj ET Q q 0 0 0 rg BT 351.26 485.10 Td (in ) Tj ET Q q 0 0 0 rg BT 361.95 485.10 Td (other ) Tj ET Q q 0 0 0 rg BT 385.40 485.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 433.85 485.10 Td (ways ) Tj ET Q q 0 0 0 rg BT 457.31 485.10 Td (including ) Tj ET Q q 0 0 0 rg BT 498.00 485.10 Td (the ) Tj ET Q q 0 0 0 rg BT 513.12 485.10 Td (development ) Tj ET Q q 0 0 0 rg BT 567.69 485.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (publications, ) Tj ET Q q 0 0 0 rg BT 89.88 473.10 Td (or ) Tj ET Q q 0 0 0 rg BT 100.71 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 110.99 473.10 Td (response ) Tj ET Q q 0 0 0 rg BT 148.48 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 158.76 473.10 Td (unsolicited ) Tj ET Q q 0 0 0 rg BT 205.14 473.10 Td (inquiries ) Tj ET Q q 0 0 0 rg BT 242.64 473.10 Td (from ) Tj ET Q q 0 0 0 rg BT 264.57 473.10 Td (doctors, ) Tj ET Q q 0 0 0 rg BT 299.01 473.10 Td (other ) Tj ET Q q 0 0 0 rg BT 322.06 473.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 356.21 473.10 Td (professionals ) Tj ET Q q 0 0 0 rg BT 411.48 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 428.42 473.10 Td (MCOs.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.53 449.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 99.15 449.10 Td (include ) Tj ET Q q 0 0 0 rg BT 131.56 449.10 Td (several ) Tj ET Q q 0 0 0 rg BT 162.85 449.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 206.37 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 223.78 449.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 246.19 449.10 Td (or) Tj ET Q q 0 0 0 rg BT 254.34 449.10 Td (ganizations. ) Tj ET Q q 0 0 0 rg BT 305.36 449.10 Td (Each ) Tj ET Q q 0 0 0 rg BT 328.31 449.10 Td (product ) Tj ET Q q 0 0 0 rg BT 361.83 449.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 405.35 449.10 Td (or) Tj ET Q q 0 0 0 rg BT 413.50 449.10 Td (ganization ) Tj ET Q q 0 0 0 rg BT 458.12 449.10 Td (is ) Tj ET Q q 0 0 0 rg BT 467.77 449.10 Td (supported ) Tj ET Q q 0 0 0 rg BT 510.18 449.10 Td (by ) Tj ET Q q 0 0 0 rg BT 523.15 449.10 Td (a ) Tj ET Q q 0 0 0 rg BT 530.57 449.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 552.98 449.10 Td (force, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (which ) Tj ET Q q 0 0 0 rg BT 61.97 437.10 Td (may ) Tj ET Q q 0 0 0 rg BT 80.71 437.10 Td (be ) Tj ET Q q 0 0 0 rg BT 91.68 437.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 138.75 437.10 Td (for ) Tj ET Q q 0 0 0 rg BT 151.94 437.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 180.14 437.10 Td (one ) Tj ET Q q 0 0 0 rg BT 196.10 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 205.96 437.10 Td (more ) Tj ET Q q 0 0 0 rg BT 228.04 437.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 266.39 437.10 Td (W) Tj ET Q q 0 0 0 rg BT 275.03 437.10 Td (e ) Tj ET Q q 0 0 0 rg BT 281.00 437.10 Td (also ) Tj ET Q q 0 0 0 rg BT 298.63 437.10 Td (have ) Tj ET Q q 0 0 0 rg BT 319.04 437.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 361.11 437.10 Td (or) Tj ET Q q 0 0 0 rg BT 369.26 437.10 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 416.33 437.10 Td (that ) Tj ET Q q 0 0 0 rg BT 432.85 437.10 Td (focus ) Tj ET Q q 0 0 0 rg BT 456.04 437.10 Td (on ) Tj ET Q q 0 0 0 rg BT 467.57 437.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 496.30 437.10 Td (classes ) Tj ET Q q 0 0 0 rg BT 525.60 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 535.46 437.10 Td (customers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (such ) Tj ET Q q 0 0 0 rg BT 57.09 425.10 Td (as ) Tj ET Q q 0 0 0 rg BT 68.18 425.10 Td (managed ) Tj ET Q q 0 0 0 rg BT 107.03 425.10 Td (care ) Tj ET Q q 0 0 0 rg BT 126.43 425.10 Td (entities ) Tj ET Q q 0 0 0 rg BT 158.08 425.10 Td (or ) Tj ET Q q 0 0 0 rg BT 169.16 425.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 199.13 425.10 Td (types ) Tj ET Q q 0 0 0 rg BT 222.99 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 234.08 425.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 277.38 425.10 Td (tools, ) Tj ET Q q 0 0 0 rg BT 302.09 425.10 Td (such ) Tj ET Q q 0 0 0 rg BT 323.18 425.10 Td (as ) Tj ET Q q 0 0 0 rg BT 334.27 425.10 Td (digital ) Tj ET Q q 0 0 0 rg BT 362.58 425.10 Td (or ) Tj ET Q q 0 0 0 rg BT 373.67 425.10 Td (consumer ) Tj ET Q q 0 0 0 rg BT 415.30 425.10 Td (communications. ) Tj ET Q q 0 0 0 rg BT 486.66 425.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 504.97 425.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 527.17 425.10 Td (forces ) Tj ET Q q 0 0 0 rg BT 554.35 425.10 Td (focus ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (on ) Tj ET Q q 0 0 0 rg BT 48.66 413.10 Td (communicating ) Tj ET Q q 0 0 0 rg BT 113.53 413.10 Td (information ) Tj ET Q q 0 0 0 rg BT 163.40 413.10 Td (about ) Tj ET Q q 0 0 0 rg BT 188.28 413.10 Td (new ) Tj ET Q q 0 0 0 rg BT 207.60 413.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 247.47 413.10 Td (products ) Tj ET Q q 0 0 0 rg BT 284.57 413.10 Td (or ) Tj ET Q q 0 0 0 rg BT 295.56 413.10 Td (uses, ) Tj ET Q q 0 0 0 rg BT 317.94 413.10 Td (as ) Tj ET Q q 0 0 0 rg BT 328.93 413.10 Td (well ) Tj ET Q q 0 0 0 rg BT 348.81 413.10 Td (as ) Tj ET Q q 0 0 0 rg BT 359.80 413.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 399.67 413.10 Td (uses ) Tj ET Q q 0 0 0 rg BT 419.55 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 430.55 413.10 Td (established ) Tj ET Q q 0 0 0 rg BT 477.64 413.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 517.24 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 534.34 413.10 Td (promotion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 401.10 Td (physicians ) Tj ET Q q 0 0 0 rg BT 91.00 401.10 Td (is ) Tj ET Q q 0 0 0 rg BT 100.17 401.10 Td (increasingly ) Tj ET Q q 0 0 0 rg BT 151.54 401.10 Td (tar) Tj ET Q q 0 0 0 rg BT 161.90 401.10 Td (geted ) Tj ET Q q 0 0 0 rg BT 186.06 401.10 Td (at ) Tj ET Q q 0 0 0 rg BT 195.78 401.10 Td (physician ) Tj ET Q q 0 0 0 rg BT 236.60 401.10 Td (specialists ) Tj ET Q q 0 0 0 rg BT 280.20 401.10 Td (who ) Tj ET Q q 0 0 0 rg BT 299.93 401.10 Td (treat ) Tj ET Q q 0 0 0 rg BT 320.19 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 334.91 401.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 368.51 401.10 Td (in ) Tj ET Q q 0 0 0 rg BT 378.79 401.10 Td (need ) Tj ET Q q 0 0 0 rg BT 400.17 401.10 Td (of ) Tj ET Q q 0 0 0 rg BT 411.00 401.10 Td (our ) Tj ET Q q 0 0 0 rg BT 426.83 401.10 Td (medicines.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.84 377.10 Td (products ) Tj ET Q q 0 0 0 rg BT 90.57 377.10 Td (are ) Tj ET Q q 0 0 0 rg BT 105.07 377.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 124.03 377.10 Td (principally ) Tj ET Q q 0 0 0 rg BT 169.65 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 179.71 377.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 231.71 377.10 Td (specialty ) Tj ET Q q 0 0 0 rg BT 269.55 377.10 Td (distributors, ) Tj ET Q q 0 0 0 rg BT 319.90 377.10 Td (and ) Tj ET Q q 0 0 0 rg BT 336.63 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 346.69 377.10 Td (a ) Tj ET Q q 0 0 0 rg BT 353.42 377.10 Td (lesser ) Tj ET Q q 0 0 0 rg BT 378.48 377.10 Td (extent, ) Tj ET Q q 0 0 0 rg BT 407.71 377.10 Td (directly ) Tj ET Q q 0 0 0 rg BT 440.54 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 450.61 377.10 Td (distributors, ) Tj ET Q q 0 0 0 rg BT 500.96 377.10 Td (retailers, ) Tj ET Q q 0 0 0 rg BT 537.96 377.10 Td (hospitals, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (clinics, ) Tj ET Q q 0 0 0 rg BT 66.66 365.10 Td (government ) Tj ET Q q 0 0 0 rg BT 116.48 365.10 Td (agencies ) Tj ET Q q 0 0 0 rg BT 152.97 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 169.46 365.10 Td (pharmacies. ) Tj ET Q q 0 0 0 rg BT 219.55 365.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 243.82 365.10 Td (to ) Tj ET Q q 0 0 0 rg BT 253.65 365.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 278.48 365.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 288.03 365.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 327.30 365.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.68 365.10 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.68 365.10 Td (. ) Tj ET Q q 0 0 0 rg BT 412.24 365.10 Td (Business ) Tj ET Q q 0 0 0 rg BT 449.86 365.10 Td (Segment ) Tj ET Q q 0 0 0 rg BT 486.91 365.10 Td (Information” ) Tj ET Q q 0 0 0 rg BT 541.17 365.10 Td (for ) Tj ET Q q 0 0 0 rg BT 554.89 365.10 Td (gross ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 74.04 353.10 Td (to ) Tj ET Q q 0 0 0 rg BT 84.32 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 99.03 353.10 Td (three ) Tj ET Q q 0 0 0 rg BT 121.52 353.10 Td (lar) Tj ET Q q 0 0 0 rg BT 131.88 353.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 150.49 353.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 214.07 353.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 263.77 353.10 Td (in ) Tj ET Q q 0 0 0 rg BT 274.05 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 288.77 353.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 309.05 353.10 Td (as ) Tj ET Q q 0 0 0 rg BT 319.88 353.10 Td (a ) Tj ET Q q 0 0 0 rg BT 326.82 353.10 Td (percentage ) Tj ET Q q 0 0 0 rg BT 372.62 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 383.45 353.10 Td (our ) Tj ET Q q 0 0 0 rg BT 399.28 353.10 Td (global ) Tj ET Q q 0 0 0 rg BT 426.78 353.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 450.39 353.10 Td (revenues.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 55.03 329.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 76.29 329.10 Td (business ) Tj ET Q q 0 0 0 rg BT 113.65 329.10 Td (has ) Tj ET Q q 0 0 0 rg BT 130.46 329.10 Td (DSAs ) Tj ET Q q 0 0 0 rg BT 157.83 329.10 Td (with ) Tj ET Q q 0 0 0 rg BT 179.08 329.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 233.11 329.10 Td (all ) Tj ET Q q 0 0 0 rg BT 246.58 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 258.39 329.10 Td (our ) Tj ET Q q 0 0 0 rg BT 275.19 329.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 301.43 329.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 348.22 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 366.14 329.10 Td (distributor ) Tj ET Q q 0 0 0 rg BT 411.28 329.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 455.30 329.10 Td (that ) Tj ET Q q 0 0 0 rg BT 473.77 329.10 Td (allow ) Tj ET Q q 0 0 0 rg BT 499.46 329.10 Td (us ) Tj ET Q q 0 0 0 rg BT 511.83 329.10 Td (to ) Tj ET Q q 0 0 0 rg BT 523.09 329.10 Td (monitor ) Tj ET Q q 0 0 0 rg BT 558.23 329.10 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 81.64 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 98.40 317.10 Td (distributor ) Tj ET Q q 0 0 0 rg BT 142.39 317.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 183.04 317.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 208.69 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 225.45 317.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 259.98 317.10 Td (those ) Tj ET Q q 0 0 0 rg BT 283.41 317.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 332.94 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 349.70 317.10 Td (distributors ) Tj ET Q q 0 0 0 rg BT 397.58 317.10 Td (to ) Tj ET Q q 0 0 0 rg BT 407.68 317.10 Td (maintain ) Tj ET Q q 0 0 0 rg BT 445.00 317.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 485.64 317.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 511.29 317.10 Td (that ) Tj ET Q q 0 0 0 rg BT 528.61 317.10 Td (are ) Tj ET Q q 0 0 0 rg BT 543.14 317.10 Td (no ) Tj ET Q q 0 0 0 rg BT 555.46 317.10 Td (more ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (than ) Tj ET Q q 0 0 0 rg BT 56.27 305.10 Td (one ) Tj ET Q q 0 0 0 rg BT 73.76 305.10 Td (month ) Tj ET Q q 0 0 0 rg BT 102.37 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 113.75 305.10 Td (their ) Tj ET Q q 0 0 0 rg BT 135.13 305.10 Td (demand. ) Tj ET Q q 0 0 0 rg BT 172.11 305.10 Td (The ) Tj ET Q q 0 0 0 rg BT 190.71 305.10 Td (DSAs, ) Tj ET Q q 0 0 0 rg BT 220.16 305.10 Td (including ) Tj ET Q q 0 0 0 rg BT 260.98 305.10 Td (those ) Tj ET Q q 0 0 0 rg BT 285.14 305.10 Td (with ) Tj ET Q q 0 0 0 rg BT 305.97 305.10 Td (our ) Tj ET Q q 0 0 0 rg BT 322.36 305.10 Td (three ) Tj ET Q q 0 0 0 rg BT 345.39 305.10 Td (lar) Tj ET Q q 0 0 0 rg BT 355.76 305.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 374.92 305.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 427.68 305.10 Td (expired ) Tj ET Q q 0 0 0 rg BT 460.72 305.10 Td (in ) Tj ET Q q 0 0 0 rg BT 471.55 305.10 Td (December ) Tj ET Q q 0 0 0 rg BT 515.68 305.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 541.01 305.10 Td (W) Tj ET Q q 0 0 0 rg BT 549.65 305.10 Td (e ) Tj ET Q q 0 0 0 rg BT 557.14 305.10 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (entered ) Tj ET Q q 0 0 0 rg BT 67.06 293.10 Td (into ) Tj ET Q q 0 0 0 rg BT 84.26 293.10 Td (letters ) Tj ET Q q 0 0 0 rg BT 110.33 293.10 Td (of ) Tj ET Q q 0 0 0 rg BT 120.30 293.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 163.58 293.10 Td (with ) Tj ET Q q 0 0 0 rg BT 182.99 293.10 Td (our ) Tj ET Q q 0 0 0 rg BT 197.96 293.10 Td (three ) Tj ET Q q 0 0 0 rg BT 219.58 293.10 Td (lar) Tj ET Q q 0 0 0 rg BT 229.95 293.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 247.70 293.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 296.54 293.10 Td (and ) Tj ET Q q 0 0 0 rg BT 312.62 293.10 Td (specialty ) Tj ET Q q 0 0 0 rg BT 349.80 293.10 Td (distributor ) Tj ET Q q 0 0 0 rg BT 393.10 293.10 Td (af) Tj ET Q q 0 0 0 rg BT 400.69 293.10 Td (filiates ) Tj ET Q q 0 0 0 rg BT 429.54 293.10 Td (to ) Tj ET Q q 0 0 0 rg BT 438.96 293.10 Td (both ) Tj ET Q q 0 0 0 rg BT 458.37 293.10 Td (extend ) Tj ET Q q 0 0 0 rg BT 486.67 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 500.52 293.10 Td (current ) Tj ET Q q 0 0 0 rg BT 530.48 293.10 Td (agreements ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (through ) Tj ET Q q 0 0 0 rg BT 69.61 281.10 Td (March ) Tj ET Q q 0 0 0 rg BT 98.21 281.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 120.71 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 137.65 281.10 Td (to ) Tj ET Q q 0 0 0 rg BT 147.92 281.10 Td (enter ) Tj ET Q q 0 0 0 rg BT 170.41 281.10 Td (into ) Tj ET Q q 0 0 0 rg BT 188.47 281.10 Td (final ) Tj ET Q q 0 0 0 rg BT 209.29 281.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 257.32 281.10 Td (through ) Tj ET Q q 0 0 0 rg BT 290.93 281.10 Td (December ) Tj ET Q q 0 0 0 rg BT 334.52 281.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 349.52 281.10 Td (2020 ) Tj ET Q q 0 0 0 rg BT 372.02 281.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 393.95 281.10 Td (to ) Tj ET Q q 0 0 0 rg BT 404.23 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 418.95 281.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 461.99 281.10 Td (of ) Tj ET Q q 0 0 0 rg BT 472.82 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 487.54 281.10 Td (letters ) Tj ET Q q 0 0 0 rg BT 514.47 281.10 Td (of ) Tj ET Q q 0 0 0 rg BT 525.30 281.10 Td (agreement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.73 257.10 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 92.03 257.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 136.43 257.10 Td (have ) Tj ET Q q 0 0 0 rg BT 157.48 257.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 209.65 257.10 Td (more ) Tj ET Q q 0 0 0 rg BT 232.38 257.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 257.33 257.10 Td (customers. ) Tj ET Q q 0 0 0 rg BT 302.55 257.10 Td (Information ) Tj ET Q q 0 0 0 rg BT 352.50 257.10 Td (on ) Tj ET Q q 0 0 0 rg BT 364.68 257.10 Td (available ) Tj ET Q q 0 0 0 rg BT 402.95 257.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 427.89 257.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 466.73 257.10 Td (product ) Tj ET Q q 0 0 0 rg BT 499.45 257.10 Td (level ) Tj ET Q q 0 0 0 rg BT 521.07 257.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 561.57 257.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.10 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 94.72 245.10 Td (out-movement ) Tj ET Q q 0 0 0 rg BT 154.55 245.10 Td (information ) Tj ET Q q 0 0 0 rg BT 203.28 245.10 Td (and ) Tj ET Q q 0 0 0 rg BT 219.23 245.10 Td (the ) Tj ET Q q 0 0 0 rg BT 232.96 245.10 Td (reliability ) Tj ET Q q 0 0 0 rg BT 273.35 245.10 Td (of ) Tj ET Q q 0 0 0 rg BT 283.20 245.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 327.47 245.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 360.64 245.10 Td (information ) Tj ET Q q 0 0 0 rg BT 409.37 245.10 Td (varies ) Tj ET Q q 0 0 0 rg BT 434.76 245.10 Td (widely) Tj ET Q q 0 0 0 rg BT 461.33 245.10 Td (. ) Tj ET Q q 0 0 0 rg BT 465.23 245.10 Td (W) Tj ET Q q 0 0 0 rg BT 473.87 245.10 Td (e ) Tj ET Q q 0 0 0 rg BT 479.82 245.10 Td (limit ) Tj ET Q q 0 0 0 rg BT 500.23 245.10 Td (our ) Tj ET Q q 0 0 0 rg BT 515.07 245.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 539.35 245.10 Td (customer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 57.94 233.10 Td (channel ) Tj ET Q q 0 0 0 rg BT 91.53 233.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 132.36 233.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 171.51 233.10 Td (to ) Tj ET Q q 0 0 0 rg BT 181.79 233.10 Td (where ) Tj ET Q q 0 0 0 rg BT 208.72 233.10 Td (we ) Tj ET Q q 0 0 0 rg BT 222.88 233.10 Td (can ) Tj ET Q q 0 0 0 rg BT 239.26 233.10 Td (reliably ) Tj ET Q q 0 0 0 rg BT 272.30 233.10 Td (gather ) Tj ET Q q 0 0 0 rg BT 299.78 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 316.72 233.10 Td (report ) Tj ET Q q 0 0 0 rg BT 343.10 233.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 383.92 233.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 409.75 233.10 Td (from ) Tj ET Q q 0 0 0 rg BT 431.69 233.10 Td (our ) Tj ET Q q 0 0 0 rg BT 447.52 233.10 Td (customers.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.15 209.10 Td (a ) Tj ET Q q 0 0 0 rg BT 54.41 209.10 Td (number ) Tj ET Q q 0 0 0 rg BT 87.77 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 98.92 209.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 138.40 209.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 170.11 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 181.26 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 196.29 209.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 219.40 209.10 Td (we ) Tj ET Q q 0 0 0 rg BT 233.88 209.10 Td (contract ) Tj ET Q q 0 0 0 rg BT 268.90 209.10 Td (with ) Tj ET Q q 0 0 0 rg BT 289.50 209.10 Td (distributors ) Tj ET Q q 0 0 0 rg BT 337.87 209.10 Td (to ) Tj ET Q q 0 0 0 rg BT 348.47 209.10 Td (support ) Tj ET Q q 0 0 0 rg BT 381.29 209.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 411.31 209.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 450.87 209.10 Td (The ) Tj ET Q q 0 0 0 rg BT 469.23 209.10 Td (services ) Tj ET Q q 0 0 0 rg BT 504.26 209.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 542.63 209.10 Td (by ) Tj ET Q q 0 0 0 rg BT 555.45 209.10 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (distributors ) Tj ET Q q 0 0 0 rg BT 84.41 197.10 Td (vary ) Tj ET Q q 0 0 0 rg BT 105.04 197.10 Td (by ) Tj ET Q q 0 0 0 rg BT 117.89 197.10 Td (market, ) Tj ET Q q 0 0 0 rg BT 151.01 197.10 Td (but ) Tj ET Q q 0 0 0 rg BT 166.64 197.10 Td (may ) Tj ET Q q 0 0 0 rg BT 186.72 197.10 Td (include ) Tj ET Q q 0 0 0 rg BT 219.01 197.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 267.97 197.10 Td (and ) Tj ET Q q 0 0 0 rg BT 285.27 197.10 Td (logistics; ) Tj ET Q q 0 0 0 rg BT 324.24 197.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 368.19 197.10 Td (and ) Tj ET Q q 0 0 0 rg BT 385.48 197.10 Td (pharmacovigilance; ) Tj ET Q q 0 0 0 rg BT 467.19 197.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 495.59 197.10 Td (sales, ) Tj ET Q q 0 0 0 rg BT 520.38 197.10 Td (advertising ) Tj ET Q q 0 0 0 rg BT 567.67 197.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.10 Td (promotion. ) Tj ET Q q 0 0 0 rg BT 82.67 185.10 Td (Sales ) Tj ET Q q 0 0 0 rg BT 106.27 185.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.55 185.10 Td (these ) Tj ET Q q 0 0 0 rg BT 139.60 185.10 Td (distributor) Tj ET Q q 0 0 0 rg BT 181.06 185.10 Td (-based ) Tj ET Q q 0 0 0 rg BT 209.66 185.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 248.82 185.10 Td (represented ) Tj ET Q q 0 0 0 rg BT 297.40 185.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 357.66 185.10 Td (1% ) Tj ET Q q 0 0 0 rg BT 373.49 185.10 Td (of ) Tj ET Q q 0 0 0 rg BT 384.32 185.10 Td (the ) Tj ET Q q 0 0 0 rg BT 399.04 185.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 440.70 185.10 Td (s ) Tj ET Q q 0 0 0 rg BT 447.09 185.10 Td (total ) Tj ET Q q 0 0 0 rg BT 467.37 185.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 505.40 185.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.68 185.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 535.68 185.10 Td (.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (Competition) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.94 137.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 88.00 137.10 Td (in ) Tj ET Q q 0 0 0 rg BT 98.17 137.10 Td (which ) Tj ET Q q 0 0 0 rg BT 125.00 137.10 Td (we ) Tj ET Q q 0 0 0 rg BT 139.06 137.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 175.33 137.10 Td (are ) Tj ET Q q 0 0 0 rg BT 189.93 137.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 229.53 137.10 Td (broad ) Tj ET Q q 0 0 0 rg BT 254.70 137.10 Td (based ) Tj ET Q q 0 0 0 rg BT 279.86 137.10 Td (and ) Tj ET Q q 0 0 0 rg BT 296.70 137.10 Td (highly ) Tj ET Q q 0 0 0 rg BT 324.65 137.10 Td (competitive. ) Tj ET Q q 0 0 0 rg BT 376.58 137.10 Td (W) Tj ET Q q 0 0 0 rg BT 385.22 137.10 Td (e ) Tj ET Q q 0 0 0 rg BT 392.05 137.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 428.32 137.10 Td (with ) Tj ET Q q 0 0 0 rg BT 448.50 137.10 Td (other ) Tj ET Q q 0 0 0 rg BT 471.44 137.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 516.60 137.10 Td (research-based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 57.97 125.10 Td (companies, ) Tj ET Q q 0 0 0 rg BT 106.88 125.10 Td (many ) Tj ET Q q 0 0 0 rg BT 132.74 125.10 Td (smaller ) Tj ET Q q 0 0 0 rg BT 165.81 125.10 Td (research ) Tj ET Q q 0 0 0 rg BT 202.76 125.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 249.17 125.10 Td (with ) Tj ET Q q 0 0 0 rg BT 270.59 125.10 Td (more ) Tj ET Q q 0 0 0 rg BT 294.78 125.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 326.75 125.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 374.81 125.10 Td (focus ) Tj ET Q q 0 0 0 rg BT 400.12 125.10 Td (and ) Tj ET Q q 0 0 0 rg BT 418.20 125.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 451.26 125.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 473.24 125.10 Td (manufacturers. ) Tj ET Q q 0 0 0 rg BT 536.57 125.10 Td (Important ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 85.53 113.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 115.05 113.10 Td (include ) Tj ET Q q 0 0 0 rg BT 146.80 113.10 Td (product ) Tj ET Q q 0 0 0 rg BT 179.67 113.10 Td (ef) Tj ET Q q 0 0 0 rg BT 187.26 113.10 Td (ficacy) Tj ET Q q 0 0 0 rg BT 211.03 113.10 Td (, ) Tj ET Q q 0 0 0 rg BT 215.85 113.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 242.04 113.10 Td (and ) Tj ET Q q 0 0 0 rg BT 258.80 113.10 Td (ease ) Tj ET Q q 0 0 0 rg BT 278.33 113.10 Td (of ) Tj ET Q q 0 0 0 rg BT 288.97 113.10 Td (use, ) Tj ET Q q 0 0 0 rg BT 307.12 113.10 Td (price ) Tj ET Q q 0 0 0 rg BT 329.43 113.10 Td (and ) Tj ET Q q 0 0 0 rg BT 346.18 113.10 Td (demonstrated ) Tj ET Q q 0 0 0 rg BT 402.37 113.10 Td (cost-ef) Tj ET Q q 0 0 0 rg BT 429.40 113.10 Td (fectiveness, ) Tj ET Q q 0 0 0 rg BT 478.64 113.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 521.50 113.10 Td (ef) Tj ET Q q 0 0 0 rg BT 529.09 113.10 Td (fectiveness, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.10 Td (product ) Tj ET Q q 0 0 0 rg BT 69.04 101.10 Td (labeling, ) Tj ET Q q 0 0 0 rg BT 106.25 101.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 145.40 101.10 Td (service ) Tj ET Q q 0 0 0 rg BT 176.21 101.10 Td (and ) Tj ET Q q 0 0 0 rg BT 193.14 101.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 217.30 101.10 Td (of ) Tj ET Q q 0 0 0 rg BT 228.13 101.10 Td (new ) Tj ET Q q 0 0 0 rg BT 247.28 101.10 Td (products ) Tj ET Q q 0 0 0 rg BT 284.21 101.10 Td (and ) Tj ET Q q 0 0 0 rg BT 301.15 101.10 Td (processes. ) Tj ET Q q 0 0 0 rg BT 344.46 101.10 Td (Sales ) Tj ET Q q 0 0 0 rg BT 368.06 101.10 Td (of ) Tj ET Q q 0 0 0 rg BT 378.89 101.10 Td (our ) Tj ET Q q 0 0 0 rg BT 394.71 101.10 Td (products ) Tj ET Q q 0 0 0 rg BT 431.64 101.10 Td (can ) Tj ET Q q 0 0 0 rg BT 448.02 101.10 Td (be ) Tj ET Q q 0 0 0 rg BT 459.95 101.10 Td (impacted ) Tj ET Q q 0 0 0 rg BT 499.09 101.10 Td (by ) Tj ET Q q 0 0 0 rg BT 511.59 101.10 Td (new ) Tj ET Q q 0 0 0 rg BT 530.74 101.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 561.01 101.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 89.10 Td (indicate ) Tj ET Q q 0 0 0 rg BT 69.76 89.10 Td (a ) Tj ET Q q 0 0 0 rg BT 76.32 89.10 Td (competitor) Tj ET Q q 0 0 0 rg BT 120.01 89.10 Td (’) Tj ET Q q 0 0 0 rg BT 122.79 89.10 Td (s ) Tj ET Q q 0 0 0 rg BT 128.79 89.10 Td (product ) Tj ET Q q 0 0 0 rg BT 161.45 89.10 Td (is ) Tj ET Q q 0 0 0 rg BT 170.24 89.10 Td (safer ) Tj ET Q q 0 0 0 rg BT 191.78 89.10 Td (or ) Tj ET Q q 0 0 0 rg BT 202.23 89.10 Td (more ) Tj ET Q q 0 0 0 rg BT 224.89 89.10 Td (ef) Tj ET Q q 0 0 0 rg BT 232.47 89.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 261.79 89.10 Td (for ) Tj ET Q q 0 0 0 rg BT 275.57 89.10 Td (treating ) Tj ET Q q 0 0 0 rg BT 308.22 89.10 Td (a ) Tj ET Q q 0 0 0 rg BT 314.77 89.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 345.77 89.10 Td (or ) Tj ET Q q 0 0 0 rg BT 356.21 89.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 396.63 89.10 Td (form ) Tj ET Q q 0 0 0 rg BT 418.19 89.10 Td (of ) Tj ET Q q 0 0 0 rg BT 428.63 89.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 459.62 89.10 Td (than ) Tj ET Q q 0 0 0 rg BT 478.95 89.10 Td (one ) Tj ET Q q 0 0 0 rg BT 495.51 89.10 Td (of ) Tj ET Q q 0 0 0 rg BT 505.95 89.10 Td (our ) Tj ET Q q 0 0 0 rg BT 521.40 89.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 560.45 89.10 Td (Our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 77.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 74.35 77.10 Td (also ) Tj ET Q q 0 0 0 rg BT 93.28 77.10 Td (can ) Tj ET Q q 0 0 0 rg BT 109.97 77.10 Td (be ) Tj ET Q q 0 0 0 rg BT 122.23 77.10 Td (impacted ) Tj ET Q q 0 0 0 rg BT 161.69 77.10 Td (by ) Tj ET Q q 0 0 0 rg BT 174.51 77.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 217.32 77.10 Td (labeling ) Tj ET Q q 0 0 0 rg BT 252.34 77.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 307.36 77.10 Td (relating ) Tj ET Q q 0 0 0 rg BT 340.72 77.10 Td (to ) Tj ET Q q 0 0 0 rg BT 351.32 77.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 378.01 77.10 Td (or ) Tj ET Q q 0 0 0 rg BT 389.16 77.10 Td (convenience ) Tj ET Q q 0 0 0 rg BT 441.94 77.10 Td (that ) Tj ET Q q 0 0 0 rg BT 459.75 77.10 Td (may ) Tj ET Q q 0 0 0 rg BT 479.79 77.10 Td (be ) Tj ET Q q 0 0 0 rg BT 492.04 77.10 Td (imposed ) Tj ET Q q 0 0 0 rg BT 528.75 77.10 Td (on ) Tj ET Q q 0 0 0 rg BT 541.56 77.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 65.10 Td (by ) Tj ET Q q 0 0 0 rg BT 47.99 65.10 Td (the ) Tj ET Q q 0 0 0 rg BT 62.20 65.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 81.65 65.10 Td ( ) Tj ET Q q 0 0 0 rg BT 83.65 65.10 Td (or ) Tj ET Q q 0 0 0 rg BT 93.97 65.10 Td (by ) Tj ET Q q 0 0 0 rg BT 105.96 65.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 135.73 65.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 178.81 65.10 Td (agencies ) Tj ET Q q 0 0 0 rg BT 215.23 65.10 Td (in ) Tj ET Q q 0 0 0 rg BT 225.00 65.10 Td (dif) Tj ET Q q 0 0 0 rg BT 235.93 65.10 Td (ferent ) Tj ET Q q 0 0 0 rg BT 261.23 65.10 Td (countries. ) Tj ET Q q 0 0 0 rg BT 302.38 65.10 Td (If ) Tj ET Q q 0 0 0 rg BT 311.03 65.10 Td (competitors ) Tj ET Q q 0 0 0 rg BT 360.24 65.10 Td (introduce ) Tj ET Q q 0 0 0 rg BT 399.99 65.10 Td (new ) Tj ET Q q 0 0 0 rg BT 418.65 65.10 Td (products ) Tj ET Q q 0 0 0 rg BT 455.08 65.10 Td (and ) Tj ET Q q 0 0 0 rg BT 471.51 65.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 511.82 65.10 Td (with ) Tj ET Q q 0 0 0 rg BT 531.59 65.10 Td (therapeutic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 53.10 Td (or ) Tj ET Q q 0 0 0 rg BT 46.83 53.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 65.44 53.10 Td (advantages, ) Tj ET Q q 0 0 0 rg BT 114.86 53.10 Td (our ) Tj ET Q q 0 0 0 rg BT 130.69 53.10 Td (products ) Tj ET Q q 0 0 0 rg BT 167.63 53.10 Td (can ) Tj ET Q q 0 0 0 rg BT 184.01 53.10 Td (be ) Tj ET Q q 0 0 0 rg BT 195.95 53.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 226.77 53.10 Td (to ) Tj ET Q q 0 0 0 rg BT 237.05 53.10 Td (progressive ) Tj ET Q q 0 0 0 rg BT 285.65 53.10 Td (price ) Tj ET Q q 0 0 0 rg BT 308.13 53.10 Td (reductions, ) Tj ET Q q 0 0 0 rg BT 354.79 53.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 396.70 53.10 Td (volume ) Tj ET Q q 0 0 0 rg BT 429.20 53.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.03 53.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 461.97 53.10 Td (or ) Tj ET Q q 0 0 0 rg BT 472.80 53.10 Td (both.) Tj ET Q endstream endobj 27 0 obj <> endobj 28 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Advancements ) Tj ET Q q 0 0 0 rg BT 98.00 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 108.36 749.10 Td (treating ) Tj ET Q q 0 0 0 rg BT 141.48 749.10 Td (cancer ) Tj ET Q q 0 0 0 rg BT 170.15 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 190.50 749.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 203.64 749.10 Td (therapies ) Tj ET Q q 0 0 0 rg BT 242.31 749.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 279.32 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 289.68 749.10 Td (evolve ) Tj ET Q q 0 0 0 rg BT 318.92 749.10 Td (at ) Tj ET Q q 0 0 0 rg BT 328.71 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 335.73 749.10 Td (rapid ) Tj ET Q q 0 0 0 rg BT 358.86 749.10 Td (pace. ) Tj ET Q q 0 0 0 rg BT 382.25 749.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 400.38 749.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 413.51 749.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 453.03 749.10 Td (particularly ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 501.70 749.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 531.14 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 536.22 749.10 Td (operate ) Tj ET Q q 0 0 0 rg BT 568.22 749.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 42.60 737.10 Td (highly ) Tj ET Q q 0 0 0 rg BT 70.32 737.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 119.68 737.10 Td (marketplace. ) Tj ET Q q 0 0 0 rg BT 173.20 737.10 Td (In ) Tj ET Q q 0 0 0 rg BT 183.69 737.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 218.63 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 228.57 737.10 Td (competing ) Tj ET Q q 0 0 0 rg BT 272.94 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 286.76 737.10 Td (market ) Tj ET Q q 0 0 0 rg BT 316.68 737.10 Td (share ) Tj ET Q q 0 0 0 rg BT 339.94 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 359.88 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 382.59 737.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 395.30 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 431.90 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 441.84 737.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 481.21 737.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 527.25 737.10 Td (such ) Tj ET Q q 0 0 0 rg BT 547.74 737.10 Td (as ) Tj ET Q q 0 0 0 rg BT 558.23 737.10 Td (lung ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (cancer ) Tj ET Q q 0 0 0 rg BT 65.22 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 82.79 725.10 Td (melanoma, ) Tj ET Q q 0 0 0 rg BT 130.07 725.10 Td (we ) Tj ET Q q 0 0 0 rg BT 144.86 725.10 Td (face ) Tj ET Q q 0 0 0 rg BT 164.64 725.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 205.53 725.10 Td (competition ) Tj ET Q q 0 0 0 rg BT 256.43 725.10 Td (from ) Tj ET Q q 0 0 0 rg BT 279.00 725.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 313.80 725.10 Td (competing ) Tj ET Q q 0 0 0 rg BT 359.14 725.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 372.82 725.10 Td (products ) Tj ET Q q 0 0 0 rg BT 410.39 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 428.52 725.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 460.52 725.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 479.97 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 483.10 725.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 521.22 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 536.01 725.10 Td (additional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 82.91 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 100.38 713.10 Td (for ) Tj ET Q q 0 0 0 rg BT 115.07 713.10 Td (new ) Tj ET Q q 0 0 0 rg BT 134.77 713.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 148.35 713.10 Td (agents ) Tj ET Q q 0 0 0 rg BT 176.93 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 194.95 713.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 226.85 713.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 246.30 713.10 Td ( ) Tj ET Q q 0 0 0 rg BT 249.33 713.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 287.35 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 304.82 713.10 Td (enter ) Tj ET Q q 0 0 0 rg BT 327.83 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 343.08 713.10 Td (market. ) Tj ET Q q 0 0 0 rg BT 376.38 713.10 Td (Furthermore, ) Tj ET Q q 0 0 0 rg BT 431.89 713.10 Td (as ) Tj ET Q q 0 0 0 rg BT 443.25 713.10 Td (therapies ) Tj ET Q q 0 0 0 rg BT 482.38 713.10 Td (combining ) Tj ET Q q 0 0 0 rg BT 528.18 713.10 Td (dif) Tj ET Q q 0 0 0 rg BT 539.11 713.10 Td (ferent ) Tj ET Q q 0 0 0 rg BT 565.46 713.10 Td (IO ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (products ) Tj ET Q q 0 0 0 rg BT 72.54 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 82.96 701.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 95.61 701.10 Td (products ) Tj ET Q q 0 0 0 rg BT 132.15 701.10 Td (with ) Tj ET Q q 0 0 0 rg BT 152.02 701.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 185.79 701.10 Td (chemotherapy ) Tj ET Q q 0 0 0 rg BT 244.52 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 254.95 701.10 Td (tar) Tj ET Q q 0 0 0 rg BT 265.32 701.10 Td (geted ) Tj ET Q q 0 0 0 rg BT 289.07 701.10 Td (therapy ) Tj ET Q q 0 0 0 rg BT 321.15 701.10 Td (treatments ) Tj ET Q q 0 0 0 rg BT 364.90 701.10 Td (are ) Tj ET Q q 0 0 0 rg BT 379.20 701.10 Td (investigated ) Tj ET Q q 0 0 0 rg BT 429.62 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 443.38 701.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 480.47 701.10 Td (expanded ) Tj ET Q q 0 0 0 rg BT 520.88 701.10 Td (approvals, ) Tj ET Q q 0 0 0 rg BT 564.35 701.10 Td (we ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (anticipate ) Tj ET Q q 0 0 0 rg BT 77.37 689.10 Td (that ) Tj ET Q q 0 0 0 rg BT 94.86 689.10 Td (our ) Tj ET Q q 0 0 0 rg BT 110.69 689.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 123.74 689.10 Td (products ) Tj ET Q q 0 0 0 rg BT 160.68 689.10 Td (will ) Tj ET Q q 0 0 0 rg BT 178.74 689.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 215.67 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 225.95 689.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 271.75 689.10 Td (intense ) Tj ET Q q 0 0 0 rg BT 302.58 689.10 Td (competition.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 659.10 Td (Another ) Tj ET Q q 0 0 0 rg BT 71.44 659.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 121.31 659.10 Td (challenge ) Tj ET Q q 0 0 0 rg BT 162.29 659.10 Td (we ) Tj ET Q q 0 0 0 rg BT 176.62 659.10 Td (face ) Tj ET Q q 0 0 0 rg BT 195.93 659.10 Td (is ) Tj ET Q q 0 0 0 rg BT 205.27 659.10 Td (from ) Tj ET Q q 0 0 0 rg BT 227.37 659.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 259.46 659.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 323.21 659.10 Td (manufacturers. ) Tj ET Q q 0 0 0 rg BT 385.57 659.10 Td (In ) Tj ET Q q 0 0 0 rg BT 396.56 659.10 Td (the ) Tj ET Q q 0 0 0 rg BT 411.45 659.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 431.90 659.10 Td (and ) Tj ET Q q 0 0 0 rg BT 449.00 659.10 Td (the ) Tj ET Q q 0 0 0 rg BT 463.89 659.10 Td (EU, ) Tj ET Q q 0 0 0 rg BT 482.39 659.10 Td (the ) Tj ET Q q 0 0 0 rg BT 497.27 659.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 541.03 659.10 Td (approval ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 647.10 Td (process ) Tj ET Q q 0 0 0 rg BT 69.23 647.10 Td (exempts ) Tj ET Q q 0 0 0 rg BT 105.79 647.10 Td (generics ) Tj ET Q q 0 0 0 rg BT 142.35 647.10 Td (from ) Tj ET Q q 0 0 0 rg BT 165.03 647.10 Td (costly ) Tj ET Q q 0 0 0 rg BT 192.15 647.10 Td (and ) Tj ET Q q 0 0 0 rg BT 209.83 647.10 Td (time-consuming ) Tj ET Q q 0 0 0 rg BT 278.06 647.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 310.73 647.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 341.75 647.10 Td (to ) Tj ET Q q 0 0 0 rg BT 352.77 647.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 404.88 647.10 Td (their ) Tj ET Q q 0 0 0 rg BT 426.44 647.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 453.56 647.10 Td (and ) Tj ET Q q 0 0 0 rg BT 471.24 647.10 Td (ef) Tj ET Q q 0 0 0 rg BT 478.83 647.10 Td (ficacy) Tj ET Q q 0 0 0 rg BT 502.60 647.10 Td (, ) Tj ET Q q 0 0 0 rg BT 508.34 647.10 Td (allowing ) Tj ET Q q 0 0 0 rg BT 546.58 647.10 Td (generic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 635.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 96.12 635.10 Td (to ) Tj ET Q q 0 0 0 rg BT 106.83 635.10 Td (rely ) Tj ET Q q 0 0 0 rg BT 125.30 635.10 Td (on ) Tj ET Q q 0 0 0 rg BT 138.23 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 153.38 635.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 180.18 635.10 Td (and ) Tj ET Q q 0 0 0 rg BT 197.55 635.10 Td (ef) Tj ET Q q 0 0 0 rg BT 205.14 635.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 232.49 635.10 Td (of ) Tj ET Q q 0 0 0 rg BT 243.75 635.10 Td (the ) Tj ET Q q 0 0 0 rg BT 258.90 635.10 Td (innovator ) Tj ET Q q 0 0 0 rg BT 300.15 635.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 335.48 635.10 Td (As ) Tj ET Q q 0 0 0 rg BT 349.52 635.10 Td (a ) Tj ET Q q 0 0 0 rg BT 356.89 635.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 384.53 635.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 416.89 635.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 480.89 635.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 541.01 635.10 Td (typically ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 623.10 Td (invest ) Tj ET Q q 0 0 0 rg BT 63.00 623.10 Td (far ) Tj ET Q q 0 0 0 rg BT 77.22 623.10 Td (less ) Tj ET Q q 0 0 0 rg BT 95.34 623.10 Td (in ) Tj ET Q q 0 0 0 rg BT 106.23 623.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 131.02 623.10 Td (than ) Tj ET Q q 0 0 0 rg BT 151.35 623.10 Td (research-based ) Tj ET Q q 0 0 0 rg BT 213.87 623.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 278.06 623.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 323.94 623.10 Td (and ) Tj ET Q q 0 0 0 rg BT 341.50 623.10 Td (therefore ) Tj ET Q q 0 0 0 rg BT 380.70 623.10 Td (can ) Tj ET Q q 0 0 0 rg BT 397.69 623.10 Td (price ) Tj ET Q q 0 0 0 rg BT 420.79 623.10 Td (their ) Tj ET Q q 0 0 0 rg BT 442.24 623.10 Td (products ) Tj ET Q q 0 0 0 rg BT 479.79 623.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 532.90 623.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 558.78 623.10 Td (than ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 611.10 Td (branded ) Tj ET Q q 0 0 0 rg BT 71.16 611.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 110.40 611.10 Td (Accordingly) Tj ET Q q 0 0 0 rg BT 159.73 611.10 Td (, ) Tj ET Q q 0 0 0 rg BT 165.18 611.10 Td (when ) Tj ET Q q 0 0 0 rg BT 189.79 611.10 Td (a ) Tj ET Q q 0 0 0 rg BT 197.18 611.10 Td (branded ) Tj ET Q q 0 0 0 rg BT 232.34 611.10 Td (product ) Tj ET Q q 0 0 0 rg BT 265.84 611.10 Td (loses ) Tj ET Q q 0 0 0 rg BT 288.79 611.10 Td (its ) Tj ET Q q 0 0 0 rg BT 301.19 611.10 Td (market ) Tj ET Q q 0 0 0 rg BT 331.90 611.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 375.13 611.10 Td (, ) Tj ET Q q 0 0 0 rg BT 380.58 611.10 Td (it ) Tj ET Q q 0 0 0 rg BT 389.09 611.10 Td (normally ) Tj ET Q q 0 0 0 rg BT 428.15 611.10 Td (faces ) Tj ET Q q 0 0 0 rg BT 451.63 611.10 Td (intense ) Tj ET Q q 0 0 0 rg BT 482.91 611.10 Td (price ) Tj ET Q q 0 0 0 rg BT 505.85 611.10 Td (competition ) Tj ET Q q 0 0 0 rg BT 556.56 611.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 599.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 67.16 599.10 Td (forms ) Tj ET Q q 0 0 0 rg BT 92.23 599.10 Td (of ) Tj ET Q q 0 0 0 rg BT 102.30 599.10 Td (the ) Tj ET Q q 0 0 0 rg BT 116.25 599.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 151.03 599.10 Td (Upon ) Tj ET Q q 0 0 0 rg BT 174.99 599.10 Td (the ) Tj ET Q q 0 0 0 rg BT 188.95 599.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 231.23 599.10 Td (or ) Tj ET Q q 0 0 0 rg BT 241.29 599.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 258.59 599.10 Td (of ) Tj ET Q q 0 0 0 rg BT 268.66 599.10 Td (market ) Tj ET Q q 0 0 0 rg BT 298.16 599.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 343.78 599.10 Td (on ) Tj ET Q q 0 0 0 rg BT 355.52 599.10 Td (a ) Tj ET Q q 0 0 0 rg BT 361.69 599.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 396.48 599.10 Td (we ) Tj ET Q q 0 0 0 rg BT 409.88 599.10 Td (can ) Tj ET Q q 0 0 0 rg BT 425.49 599.10 Td (lose ) Tj ET Q q 0 0 0 rg BT 443.33 599.10 Td (the ) Tj ET Q q 0 0 0 rg BT 457.29 599.10 Td (major ) Tj ET Q q 0 0 0 rg BT 482.35 599.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 512.98 599.10 Td (of ) Tj ET Q q 0 0 0 rg BT 523.04 599.10 Td (that ) Tj ET Q q 0 0 0 rg BT 539.78 599.10 Td (product's ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 587.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 70.15 587.10 Td (in ) Tj ET Q q 0 0 0 rg BT 80.42 587.10 Td (a ) Tj ET Q q 0 0 0 rg BT 87.36 587.10 Td (very ) Tj ET Q q 0 0 0 rg BT 107.63 587.10 Td (short ) Tj ET Q q 0 0 0 rg BT 130.13 587.10 Td (period ) Tj ET Q q 0 0 0 rg BT 158.18 587.10 Td (of ) Tj ET Q q 0 0 0 rg BT 169.01 587.10 Td (time.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 563.10 Td (After ) Tj ET Q q 0 0 0 rg BT 59.52 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 74.16 563.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 117.12 563.10 Td (of ) Tj ET Q q 0 0 0 rg BT 127.87 563.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 171.10 563.10 Td (, ) Tj ET Q q 0 0 0 rg BT 176.02 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 190.66 563.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 208.07 563.10 Td (of ) Tj ET Q q 0 0 0 rg BT 218.82 563.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 256.78 563.10 Td (decline ) Tj ET Q q 0 0 0 rg BT 288.07 563.10 Td (of ) Tj ET Q q 0 0 0 rg BT 298.82 563.10 Td (a ) Tj ET Q q 0 0 0 rg BT 305.68 563.10 Td (product ) Tj ET Q q 0 0 0 rg BT 338.65 563.10 Td (varies ) Tj ET Q q 0 0 0 rg BT 364.95 563.10 Td (by ) Tj ET Q q 0 0 0 rg BT 377.37 563.10 Td (country) Tj ET Q q 0 0 0 rg BT 407.26 563.10 Td (. ) Tj ET Q q 0 0 0 rg BT 412.19 563.10 Td (In ) Tj ET Q q 0 0 0 rg BT 422.94 563.10 Td (general, ) Tj ET Q q 0 0 0 rg BT 457.28 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 471.92 563.10 Td (decline ) Tj ET Q q 0 0 0 rg BT 503.21 563.10 Td (in ) Tj ET Q q 0 0 0 rg BT 513.41 563.10 Td (the ) Tj ET Q q 0 0 0 rg BT 528.05 563.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 548.25 563.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 551.10 Td (is ) Tj ET Q q 0 0 0 rg BT 44.81 551.10 Td (more ) Tj ET Q q 0 0 0 rg BT 67.50 551.10 Td (rapid ) Tj ET Q q 0 0 0 rg BT 90.19 551.10 Td (than ) Tj ET Q q 0 0 0 rg BT 109.54 551.10 Td (in ) Tj ET Q q 0 0 0 rg BT 119.46 551.10 Td (most ) Tj ET Q q 0 0 0 rg BT 141.05 551.10 Td (other ) Tj ET Q q 0 0 0 rg BT 163.74 551.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 206.98 551.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 248.27 551.10 Td (though ) Tj ET Q q 0 0 0 rg BT 278.19 551.10 Td (we ) Tj ET Q q 0 0 0 rg BT 291.99 551.10 Td (have ) Tj ET Q q 0 0 0 rg BT 313.01 551.10 Td (observed ) Tj ET Q q 0 0 0 rg BT 351.25 551.10 Td (rapid ) Tj ET Q q 0 0 0 rg BT 373.94 551.10 Td (declines ) Tj ET Q q 0 0 0 rg BT 408.84 551.10 Td (in ) Tj ET Q q 0 0 0 rg BT 418.76 551.10 Td (a ) Tj ET Q q 0 0 0 rg BT 425.34 551.10 Td (number ) Tj ET Q q 0 0 0 rg BT 458.03 551.10 Td (of ) Tj ET Q q 0 0 0 rg BT 468.50 551.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 483.97 551.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 522.77 551.10 Td (as ) Tj ET Q q 0 0 0 rg BT 533.24 551.10 Td (well. ) Tj ET Q q 0 0 0 rg BT 554.63 551.10 Td (Also, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 539.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.66 539.10 Td (declines ) Tj ET Q q 0 0 0 rg BT 85.86 539.10 Td (in ) Tj ET Q q 0 0 0 rg BT 96.08 539.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 139.61 539.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 178.70 539.10 Td (tend ) Tj ET Q q 0 0 0 rg BT 198.36 539.10 Td (to ) Tj ET Q q 0 0 0 rg BT 208.58 539.10 Td (be ) Tj ET Q q 0 0 0 rg BT 220.45 539.10 Td (more ) Tj ET Q q 0 0 0 rg BT 243.44 539.10 Td (rapid ) Tj ET Q q 0 0 0 rg BT 266.42 539.10 Td (than ) Tj ET Q q 0 0 0 rg BT 286.08 539.10 Td (in ) Tj ET Q q 0 0 0 rg BT 296.30 539.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 343.17 539.10 Td (countries. ) Tj ET Q q 0 0 0 rg BT 384.59 539.10 Td (The ) Tj ET Q q 0 0 0 rg BT 402.57 539.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 420.00 539.10 Td (of ) Tj ET Q q 0 0 0 rg BT 430.77 539.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 468.74 539.10 Td (decline ) Tj ET Q q 0 0 0 rg BT 500.05 539.10 Td (after ) Tj ET Q q 0 0 0 rg BT 520.81 539.10 Td (the ) Tj ET Q q 0 0 0 rg BT 535.46 539.10 Td (expiration ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 527.10 Td (of ) Tj ET Q q 0 0 0 rg BT 45.93 527.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 91.42 527.10 Td (has ) Tj ET Q q 0 0 0 rg BT 106.35 527.10 Td (also ) Tj ET Q q 0 0 0 rg BT 124.06 527.10 Td (historically ) Tj ET Q q 0 0 0 rg BT 170.65 527.10 Td (been ) Tj ET Q q 0 0 0 rg BT 191.13 527.10 Td (influenced ) Tj ET Q q 0 0 0 rg BT 234.93 527.10 Td (by ) Tj ET Q q 0 0 0 rg BT 246.53 527.10 Td (product ) Tj ET Q q 0 0 0 rg BT 278.68 527.10 Td (characteristics. ) Tj ET Q q 0 0 0 rg BT 339.97 527.10 Td (For ) Tj ET Q q 0 0 0 rg BT 355.46 527.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 393.44 527.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 417.26 527.10 Td (that ) Tj ET Q q 0 0 0 rg BT 433.86 527.10 Td (are ) Tj ET Q q 0 0 0 rg BT 447.67 527.10 Td (used ) Tj ET Q q 0 0 0 rg BT 467.60 527.10 Td (in ) Tj ET Q q 0 0 0 rg BT 476.98 527.10 Td (a ) Tj ET Q q 0 0 0 rg BT 483.02 527.10 Td (lar) Tj ET Q q 0 0 0 rg BT 493.38 527.10 Td (ge ) Tj ET Q q 0 0 0 rg BT 504.42 527.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 533.24 527.10 Td (population ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 515.10 Td (\(e.g., ) Tj ET Q q 0 0 0 rg BT 58.24 515.10 Td (those ) Tj ET Q q 0 0 0 rg BT 81.32 515.10 Td (prescribed ) Tj ET Q q 0 0 0 rg BT 124.93 515.10 Td (by ) Tj ET Q q 0 0 0 rg BT 136.90 515.10 Td (key ) Tj ET Q q 0 0 0 rg BT 153.31 515.10 Td (primary ) Tj ET Q q 0 0 0 rg BT 186.93 515.10 Td (care ) Tj ET Q q 0 0 0 rg BT 205.55 515.10 Td (physicians\) ) Tj ET Q q 0 0 0 rg BT 253.06 515.10 Td (tend ) Tj ET Q q 0 0 0 rg BT 272.25 515.10 Td (to ) Tj ET Q q 0 0 0 rg BT 282.00 515.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 327.27 515.10 Td (more ) Tj ET Q q 0 0 0 rg BT 349.78 515.10 Td (rapid ) Tj ET Q q 0 0 0 rg BT 372.30 515.10 Td (declines ) Tj ET Q q 0 0 0 rg BT 407.03 515.10 Td (than ) Tj ET Q q 0 0 0 rg BT 426.22 515.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 450.41 515.10 Td (in ) Tj ET Q q 0 0 0 rg BT 460.16 515.10 Td (specialized ) Tj ET Q q 0 0 0 rg BT 506.54 515.10 Td (areas ) Tj ET Q q 0 0 0 rg BT 529.05 515.10 Td (of ) Tj ET Q q 0 0 0 rg BT 539.35 515.10 Td (medicine ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 503.10 Td (\(e.g., ) Tj ET Q q 0 0 0 rg BT 58.58 503.10 Td (oncology\). ) Tj ET Q q 0 0 0 rg BT 103.94 503.10 Td (Drugs ) Tj ET Q q 0 0 0 rg BT 130.69 503.10 Td (that ) Tj ET Q q 0 0 0 rg BT 148.00 503.10 Td (are ) Tj ET Q q 0 0 0 rg BT 162.52 503.10 Td (more ) Tj ET Q q 0 0 0 rg BT 185.37 503.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 222.12 503.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.21 503.10 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 284.49 503.10 Td (\(e.g., ) Tj ET Q q 0 0 0 rg BT 307.07 503.10 Td (sterile ) Tj ET Q q 0 0 0 rg BT 333.81 503.10 Td (injectable ) Tj ET Q q 0 0 0 rg BT 374.99 503.10 Td (products\) ) Tj ET Q q 0 0 0 rg BT 415.07 503.10 Td (usually ) Tj ET Q q 0 0 0 rg BT 446.27 503.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 491.88 503.10 Td (a ) Tj ET Q q 0 0 0 rg BT 498.63 503.10 Td (slower ) Tj ET Q q 0 0 0 rg BT 527.60 503.10 Td (decline ) Tj ET Q q 0 0 0 rg BT 558.79 503.10 Td (than ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 491.10 Td (those ) Tj ET Q q 0 0 0 rg BT 59.61 491.10 Td (that ) Tj ET Q q 0 0 0 rg BT 77.10 491.10 Td (are ) Tj ET Q q 0 0 0 rg BT 91.81 491.10 Td (simpler ) Tj ET Q q 0 0 0 rg BT 124.31 491.10 Td (to ) Tj ET Q q 0 0 0 rg BT 134.58 491.10 Td (manufacture.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 467.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.99 467.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 76.85 467.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 116.17 467.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 147.71 467.10 Td (the ) Tj ET Q q 0 0 0 rg BT 162.59 467.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 185.54 467.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 212.63 467.10 Td (protection ) Tj ET Q q 0 0 0 rg BT 255.83 467.10 Td (is ) Tj ET Q q 0 0 0 rg BT 265.16 467.10 Td (weak ) Tj ET Q q 0 0 0 rg BT 288.92 467.10 Td (or ) Tj ET Q q 0 0 0 rg BT 299.91 467.10 Td (nonexistent ) Tj ET Q q 0 0 0 rg BT 348.67 467.10 Td (and ) Tj ET Q q 0 0 0 rg BT 365.77 467.10 Td (we ) Tj ET Q q 0 0 0 rg BT 380.09 467.10 Td (must ) Tj ET Q q 0 0 0 rg BT 402.20 467.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 438.73 467.10 Td (with ) Tj ET Q q 0 0 0 rg BT 459.17 467.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 491.26 467.10 Td (versions ) Tj ET Q q 0 0 0 rg BT 527.25 467.10 Td (shortly ) Tj ET Q q 0 0 0 rg BT 557.68 467.10 Td (after ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 455.10 Td (we ) Tj ET Q q 0 0 0 rg BT 50.38 455.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 79.76 455.10 Td (our ) Tj ET Q q 0 0 0 rg BT 95.81 455.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 140.74 455.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 180.40 455.10 Td (In ) Tj ET Q q 0 0 0 rg BT 191.45 455.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 229.45 455.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 261.59 455.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 325.39 455.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 370.87 455.10 Td (may ) Tj ET Q q 0 0 0 rg BT 390.81 455.10 Td (introduce ) Tj ET Q q 0 0 0 rg BT 431.30 455.10 Td (a ) Tj ET Q q 0 0 0 rg BT 438.46 455.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 470.60 455.10 Td (product ) Tj ET Q q 0 0 0 rg BT 503.87 455.10 Td (before ) Tj ET Q q 0 0 0 rg BT 532.13 455.10 Td (exclusivity ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 443.10 Td (has ) Tj ET Q q 0 0 0 rg BT 51.07 443.10 Td (expired, ) Tj ET Q q 0 0 0 rg BT 85.29 443.10 Td (and ) Tj ET Q q 0 0 0 rg BT 101.47 443.10 Td (before ) Tj ET Q q 0 0 0 rg BT 128.75 443.10 Td (the ) Tj ET Q q 0 0 0 rg BT 142.71 443.10 Td (resolution ) Tj ET Q q 0 0 0 rg BT 184.44 443.10 Td (of ) Tj ET Q q 0 0 0 rg BT 194.51 443.10 Td (any ) Tj ET Q q 0 0 0 rg BT 210.69 443.10 Td (related ) Tj ET Q q 0 0 0 rg BT 239.63 443.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 265.80 443.10 Td (litigation. ) Tj ET Q q 0 0 0 rg BT 306.15 443.10 Td (For ) Tj ET Q q 0 0 0 rg BT 321.78 443.10 Td (more ) Tj ET Q q 0 0 0 rg BT 344.07 443.10 Td (information ) Tj ET Q q 0 0 0 rg BT 393.02 443.10 Td (about ) Tj ET Q q 0 0 0 rg BT 416.98 443.10 Td (market ) Tj ET Q q 0 0 0 rg BT 446.48 443.10 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 489.71 443.10 Td (, ) Tj ET Q q 0 0 0 rg BT 493.95 443.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 514.56 443.10 Td (to ) Tj ET Q q 0 0 0 rg BT 524.08 443.10 Td (“—Products, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 431.10 Td (Intellectual ) Tj ET Q q 0 0 0 rg BT 83.48 431.10 Td (Property ) Tj ET Q q 0 0 0 rg BT 120.41 431.10 Td (and ) Tj ET Q q 0 0 0 rg BT 137.35 431.10 Td (Product ) Tj ET Q q 0 0 0 rg BT 170.96 431.10 Td (Exclusivity”.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 407.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 407.10 Td (e ) Tj ET Q q 0 0 0 rg BT 50.52 407.10 Td (believe ) Tj ET Q q 0 0 0 rg BT 80.83 407.10 Td (our ) Tj ET Q q 0 0 0 rg BT 95.61 407.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 136.48 407.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 185.13 407.10 Td (position ) Tj ET Q q 0 0 0 rg BT 218.80 407.10 Td (depends ) Tj ET Q q 0 0 0 rg BT 253.01 407.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 274.46 407.10 Td (our ) Tj ET Q q 0 0 0 rg BT 289.23 407.10 Td (success ) Tj ET Q q 0 0 0 rg BT 320.66 407.10 Td (in ) Tj ET Q q 0 0 0 rg BT 329.88 407.10 Td (discovering ) Tj ET Q q 0 0 0 rg BT 377.98 407.10 Td (and ) Tj ET Q q 0 0 0 rg BT 393.86 407.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 439.74 407.10 Td (innovative, ) Tj ET Q q 0 0 0 rg BT 485.90 407.10 Td (cost-ef) Tj ET Q q 0 0 0 rg BT 512.92 407.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 541.57 407.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 395.10 Td (that ) Tj ET Q q 0 0 0 rg BT 53.98 395.10 Td (serve ) Tj ET Q q 0 0 0 rg BT 78.07 395.10 Td (unmet ) Tj ET Q q 0 0 0 rg BT 106.05 395.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 140.68 395.10 Td (needs, ) Tj ET Q q 0 0 0 rg BT 168.94 395.10 Td (along ) Tj ET Q q 0 0 0 rg BT 194.14 395.10 Td (with ) Tj ET Q q 0 0 0 rg BT 214.90 395.10 Td (our ) Tj ET Q q 0 0 0 rg BT 231.22 395.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 259.76 395.10 Td (to ) Tj ET Q q 0 0 0 rg BT 270.52 395.10 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 323.48 395.10 Td (products ) Tj ET Q q 0 0 0 rg BT 360.90 395.10 Td (ef) Tj ET Q q 0 0 0 rg BT 368.49 395.10 Td (ficiently ) Tj ET Q q 0 0 0 rg BT 404.80 395.10 Td (and ) Tj ET Q q 0 0 0 rg BT 422.22 395.10 Td (to ) Tj ET Q q 0 0 0 rg BT 432.98 395.10 Td (market ) Tj ET Q q 0 0 0 rg BT 463.73 395.10 Td (them ) Tj ET Q q 0 0 0 rg BT 486.72 395.10 Td (ef) Tj ET Q q 0 0 0 rg BT 494.30 395.10 Td (fectively ) Tj ET Q q 0 0 0 rg BT 532.27 395.10 Td (in ) Tj ET Q q 0 0 0 rg BT 543.03 395.10 Td (a ) Tj ET Q q 0 0 0 rg BT 550.46 395.10 Td (highly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 383.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 85.71 383.10 Td (environment.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 359.10 Td (Pricing, Price Constraints and Market ) Tj ET Q q 0 0 0 rg BT 202.09 359.10 Td (Access) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 335.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.67 335.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 96.33 335.10 Td (are ) Tj ET Q q 0 0 0 rg BT 110.65 335.10 Td (priced ) Tj ET Q q 0 0 0 rg BT 137.75 335.10 Td (based ) Tj ET Q q 0 0 0 rg BT 162.64 335.10 Td (on ) Tj ET Q q 0 0 0 rg BT 174.75 335.10 Td (a ) Tj ET Q q 0 0 0 rg BT 181.31 335.10 Td (number ) Tj ET Q q 0 0 0 rg BT 213.97 335.10 Td (of ) Tj ET Q q 0 0 0 rg BT 224.42 335.10 Td (factors, ) Tj ET Q q 0 0 0 rg BT 256.24 335.10 Td (including ) Tj ET Q q 0 0 0 rg BT 296.13 335.10 Td (the ) Tj ET Q q 0 0 0 rg BT 310.47 335.10 Td (value ) Tj ET Q q 0 0 0 rg BT 334.24 335.10 Td (of ) Tj ET Q q 0 0 0 rg BT 344.69 335.10 Td (scientific ) Tj ET Q q 0 0 0 rg BT 383.45 335.10 Td (innovation ) Tj ET Q q 0 0 0 rg BT 428.34 335.10 Td (for ) Tj ET Q q 0 0 0 rg BT 442.12 335.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 475.34 335.10 Td (and ) Tj ET Q q 0 0 0 rg BT 491.90 335.10 Td (society ) Tj ET Q q 0 0 0 rg BT 522.34 335.10 Td (in ) Tj ET Q q 0 0 0 rg BT 532.23 335.10 Td (the ) Tj ET Q q 0 0 0 rg BT 546.57 335.10 Td (context ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 323.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.96 323.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 77.35 323.10 Td (health ) Tj ET Q q 0 0 0 rg BT 104.42 323.10 Td (care ) Tj ET Q q 0 0 0 rg BT 123.69 323.10 Td (spend, ) Tj ET Q q 0 0 0 rg BT 152.15 323.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 193.65 323.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 223.49 323.10 Td (impacting ) Tj ET Q q 0 0 0 rg BT 266.11 323.10 Td (health ) Tj ET Q q 0 0 0 rg BT 293.17 323.10 Td (care ) Tj ET Q q 0 0 0 rg BT 312.45 323.10 Td (systems’) Tj ET Q q 0 0 0 rg BT 346.70 323.10 Td ( ) Tj ET Q q 0 0 0 rg BT 349.33 323.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 377.51 323.10 Td (to ) Tj ET Q q 0 0 0 rg BT 387.92 323.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 421.10 323.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 469.26 323.10 Td (and ) Tj ET Q q 0 0 0 rg BT 486.33 323.10 Td (sustainable ) Tj ET Q q 0 0 0 rg BT 533.39 323.10 Td (access ) Tj ET Q q 0 0 0 rg BT 561.56 323.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 311.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.01 311.10 Td (necessity ) Tj ET Q q 0 0 0 rg BT 90.47 311.10 Td (to ) Tj ET Q q 0 0 0 rg BT 101.04 311.10 Td (sustain ) Tj ET Q q 0 0 0 rg BT 131.62 311.10 Td (our ) Tj ET Q q 0 0 0 rg BT 147.75 311.10 Td (investment ) Tj ET Q q 0 0 0 rg BT 194.43 311.10 Td (in ) Tj ET Q q 0 0 0 rg BT 205.00 311.10 Td (innovation ) Tj ET Q q 0 0 0 rg BT 250.58 311.10 Td (platforms ) Tj ET Q q 0 0 0 rg BT 291.70 311.10 Td (to ) Tj ET Q q 0 0 0 rg BT 302.27 311.10 Td (address ) Tj ET Q q 0 0 0 rg BT 335.06 311.10 Td (serious ) Tj ET Q q 0 0 0 rg BT 366.19 311.10 Td (unmet ) Tj ET Q q 0 0 0 rg BT 393.98 311.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 428.43 311.10 Td (needs. ) Tj ET Q q 0 0 0 rg BT 456.50 311.10 Td (Central ) Tj ET Q q 0 0 0 rg BT 488.73 311.10 Td (to ) Tj ET Q q 0 0 0 rg BT 499.31 311.10 Td (price ) Tj ET Q q 0 0 0 rg BT 522.09 311.10 Td (is ) Tj ET Q q 0 0 0 rg BT 531.56 311.10 Td (the ) Tj ET Q q 0 0 0 rg BT 546.57 311.10 Td (clinical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 299.10 Td (value ) Tj ET Q q 0 0 0 rg BT 60.44 299.10 Td (that ) Tj ET Q q 0 0 0 rg BT 78.22 299.10 Td (this ) Tj ET Q q 0 0 0 rg BT 95.46 299.10 Td (innovation ) Tj ET Q q 0 0 0 rg BT 141.02 299.10 Td (brings ) Tj ET Q q 0 0 0 rg BT 168.81 299.10 Td (to ) Tj ET Q q 0 0 0 rg BT 179.37 299.10 Td (the ) Tj ET Q q 0 0 0 rg BT 194.38 299.10 Td (market, ) Tj ET Q q 0 0 0 rg BT 227.43 299.10 Td (the ) Tj ET Q q 0 0 0 rg BT 242.43 299.10 Td (current ) Tj ET Q q 0 0 0 rg BT 273.53 299.10 Td (landscape ) Tj ET Q q 0 0 0 rg BT 315.75 299.10 Td (of ) Tj ET Q q 0 0 0 rg BT 326.86 299.10 Td (alternative ) Tj ET Q q 0 0 0 rg BT 371.85 299.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 412.39 299.10 Td (options, ) Tj ET Q q 0 0 0 rg BT 447.13 299.10 Td (the ) Tj ET Q q 0 0 0 rg BT 462.13 299.10 Td (goal ) Tj ET Q q 0 0 0 rg BT 482.14 299.10 Td (of ) Tj ET Q q 0 0 0 rg BT 493.25 299.10 Td (ensuring ) Tj ET Q q 0 0 0 rg BT 530.48 299.10 Td (appropriate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 287.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 65.01 287.10 Td (access ) Tj ET Q q 0 0 0 rg BT 92.35 287.10 Td (to ) Tj ET Q q 0 0 0 rg BT 101.92 287.10 Td (this ) Tj ET Q q 0 0 0 rg BT 118.17 287.10 Td (innovation ) Tj ET Q q 0 0 0 rg BT 162.74 287.10 Td (and ) Tj ET Q q 0 0 0 rg BT 178.98 287.10 Td (sustaining ) Tj ET Q q 0 0 0 rg BT 221.33 287.10 Td (investment ) Tj ET Q q 0 0 0 rg BT 267.01 287.10 Td (in ) Tj ET Q q 0 0 0 rg BT 276.59 287.10 Td (creative ) Tj ET Q q 0 0 0 rg BT 310.03 287.10 Td (platforms. ) Tj ET Q q 0 0 0 rg BT 352.52 287.10 Td (W) Tj ET Q q 0 0 0 rg BT 361.16 287.10 Td (e ) Tj ET Q q 0 0 0 rg BT 367.40 287.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 403.63 287.10 Td (to ) Tj ET Q q 0 0 0 rg BT 413.20 287.10 Td (explore ) Tj ET Q q 0 0 0 rg BT 444.99 287.10 Td (new ) Tj ET Q q 0 0 0 rg BT 463.45 287.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 493.57 287.10 Td (approaches ) Tj ET Q q 0 0 0 rg BT 540.34 287.10 Td (to ) Tj ET Q q 0 0 0 rg BT 549.92 287.10 Td (ensure ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 275.10 Td (that ) Tj ET Q q 0 0 0 rg BT 53.15 275.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 86.41 275.10 Td (have ) Tj ET Q q 0 0 0 rg BT 107.45 275.10 Td (access ) Tj ET Q q 0 0 0 rg BT 135.14 275.10 Td (to ) Tj ET Q q 0 0 0 rg BT 145.08 275.10 Td (our ) Tj ET Q q 0 0 0 rg BT 160.56 275.10 Td (medicines. ) Tj ET Q q 0 0 0 rg BT 205.76 275.10 Td (Enhancing ) Tj ET Q q 0 0 0 rg BT 250.68 275.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 280.05 275.10 Td (access ) Tj ET Q q 0 0 0 rg BT 307.75 275.10 Td (to ) Tj ET Q q 0 0 0 rg BT 317.68 275.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 360.38 275.10 Td (is ) Tj ET Q q 0 0 0 rg BT 369.21 275.10 Td (a ) Tj ET Q q 0 0 0 rg BT 375.81 275.10 Td (priority ) Tj ET Q q 0 0 0 rg BT 407.96 275.10 Td (for ) Tj ET Q q 0 0 0 rg BT 421.78 275.10 Td (us. ) Tj ET Q q 0 0 0 rg BT 435.17 275.10 Td (W) Tj ET Q q 0 0 0 rg BT 443.81 275.10 Td (e ) Tj ET Q q 0 0 0 rg BT 450.40 275.10 Td (are ) Tj ET Q q 0 0 0 rg BT 464.77 275.10 Td (focused ) Tj ET Q q 0 0 0 rg BT 498.02 275.10 Td (on ) Tj ET Q q 0 0 0 rg BT 510.18 275.10 Td (of) Tj ET Q q 0 0 0 rg BT 518.33 275.10 Td (fering ) Tj ET Q q 0 0 0 rg BT 544.36 275.10 Td (creative ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 263.10 Td (tiered ) Tj ET Q q 0 0 0 rg BT 60.33 263.10 Td (pricing, ) Tj ET Q q 0 0 0 rg BT 92.72 263.10 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 132.61 263.10 Td (licensing, ) Tj ET Q q 0 0 0 rg BT 172.78 263.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 234.33 263.10 Td (support ) Tj ET Q q 0 0 0 rg BT 265.90 263.10 Td (and ) Tj ET Q q 0 0 0 rg BT 281.90 263.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 310.68 263.10 Td (assistance ) Tj ET Q q 0 0 0 rg BT 352.23 263.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 391.57 263.10 Td (to ) Tj ET Q q 0 0 0 rg BT 400.91 263.10 Td (optimize ) Tj ET Q q 0 0 0 rg BT 437.47 263.10 Td (access ) Tj ET Q q 0 0 0 rg BT 464.57 263.10 Td (while ) Tj ET Q q 0 0 0 rg BT 488.35 263.10 Td (protecting ) Tj ET Q q 0 0 0 rg BT 530.46 263.10 Td (innovation; ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 251.10 Td (advocating ) Tj ET Q q 0 0 0 rg BT 84.45 251.10 Td (for ) Tj ET Q q 0 0 0 rg BT 100.69 251.10 Td (sustainable ) Tj ET Q q 0 0 0 rg BT 149.70 251.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 195.36 251.10 Td (policies ) Tj ET Q q 0 0 0 rg BT 231.05 251.10 Td (and ) Tj ET Q q 0 0 0 rg BT 250.06 251.10 Td (infrastructure, ) Tj ET Q q 0 0 0 rg BT 311.01 251.10 Td (leveraging ) Tj ET Q q 0 0 0 rg BT 357.79 251.10 Td (advocacy/payer) Tj ET Q q 0 0 0 rg BT 420.90 251.10 Td (’) Tj ET Q q 0 0 0 rg BT 423.68 251.10 Td (s ) Tj ET Q q 0 0 0 rg BT 432.15 251.10 Td (input ) Tj ET Q q 0 0 0 rg BT 457.28 251.10 Td (and ) Tj ET Q q 0 0 0 rg BT 476.30 251.10 Td (utilizing ) Tj ET Q q 0 0 0 rg BT 514.21 251.10 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 567.67 251.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 239.10 Td (appropriate; ) Tj ET Q q 0 0 0 rg BT 85.94 239.10 Td (and ) Tj ET Q q 0 0 0 rg BT 102.00 239.10 Td (improving ) Tj ET Q q 0 0 0 rg BT 145.29 239.10 Td (access ) Tj ET Q q 0 0 0 rg BT 172.46 239.10 Td (to ) Tj ET Q q 0 0 0 rg BT 181.86 239.10 Td (care ) Tj ET Q q 0 0 0 rg BT 200.13 239.10 Td (and ) Tj ET Q q 0 0 0 rg BT 216.20 239.10 Td (supportive ) Tj ET Q q 0 0 0 rg BT 260.04 239.10 Td (services ) Tj ET Q q 0 0 0 rg BT 293.87 239.10 Td (for ) Tj ET Q q 0 0 0 rg BT 307.16 239.10 Td (vulnerable ) Tj ET Q q 0 0 0 rg BT 350.99 239.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 383.71 239.10 Td (through ) Tj ET Q q 0 0 0 rg BT 416.45 239.10 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 466.95 239.10 Td (and ) Tj ET Q q 0 0 0 rg BT 483.02 239.10 Td (demonstration ) Tj ET Q q 0 0 0 rg BT 541.85 239.10 Td (projects. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 227.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 227.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.45 227.10 Td (are ) Tj ET Q q 0 0 0 rg BT 66.03 227.10 Td (also ) Tj ET Q q 0 0 0 rg BT 84.52 227.10 Td (monitoring ) Tj ET Q q 0 0 0 rg BT 131.33 227.10 Td (new ) Tj ET Q q 0 0 0 rg BT 150.37 227.10 Td (state ) Tj ET Q q 0 0 0 rg BT 171.07 227.10 Td (laws, ) Tj ET Q q 0 0 0 rg BT 194.27 227.10 Td (such ) Tj ET Q q 0 0 0 rg BT 214.98 227.10 Td (as ) Tj ET Q q 0 0 0 rg BT 225.68 227.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 246.39 227.10 Td (that ) Tj ET Q q 0 0 0 rg BT 263.76 227.10 Td (have ) Tj ET Q q 0 0 0 rg BT 285.01 227.10 Td (recently ) Tj ET Q q 0 0 0 rg BT 319.58 227.10 Td (been ) Tj ET Q q 0 0 0 rg BT 340.83 227.10 Td (enacted ) Tj ET Q q 0 0 0 rg BT 373.74 227.10 Td (in ) Tj ET Q q 0 0 0 rg BT 383.89 227.10 Td (California, ) Tj ET Q q 0 0 0 rg BT 429.14 227.10 Td (V) Tj ET Q q 0 0 0 rg BT 435.25 227.10 Td (ermont, ) Tj ET Q q 0 0 0 rg BT 468.45 227.10 Td (Nevada ) Tj ET Q q 0 0 0 rg BT 501.36 227.10 Td (and ) Tj ET Q q 0 0 0 rg BT 518.18 227.10 Td (New ) Tj ET Q q 0 0 0 rg BT 539.08 227.10 Td (Y) Tj ET Q q 0 0 0 rg BT 545.30 227.10 Td (ork ) Tj ET Q q 0 0 0 rg BT 561.01 227.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 215.10 Td (are ) Tj ET Q q 0 0 0 rg BT 50.49 215.10 Td (focused ) Tj ET Q q 0 0 0 rg BT 83.87 215.10 Td (on ) Tj ET Q q 0 0 0 rg BT 96.15 215.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 116.76 215.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 147.36 215.10 Td (transparency ) Tj ET Q q 0 0 0 rg BT 200.73 215.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 228.55 215.10 Td (limiting ) Tj ET Q q 0 0 0 rg BT 262.50 215.10 Td (state ) Tj ET Q q 0 0 0 rg BT 283.11 215.10 Td (spending ) Tj ET Q q 0 0 0 rg BT 321.50 215.10 Td (on ) Tj ET Q q 0 0 0 rg BT 333.78 215.10 Td (drugs. ) Tj ET Q q 0 0 0 rg BT 360.62 215.10 Td (These ) Tj ET Q q 0 0 0 rg BT 386.77 215.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 407.38 215.10 Td (could ) Tj ET Q q 0 0 0 rg BT 431.88 215.10 Td (create ) Tj ET Q q 0 0 0 rg BT 458.02 215.10 Td (new ) Tj ET Q q 0 0 0 rg BT 476.96 215.10 Td (constraints ) Tj ET Q q 0 0 0 rg BT 522.57 215.10 Td (on ) Tj ET Q q 0 0 0 rg BT 534.85 215.10 Td (our ) Tj ET Q q 0 0 0 rg BT 550.46 215.10 Td (ability ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 203.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 203.10 Td (set ) Tj ET Q q 0 0 0 rg BT 59.89 203.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 86.26 203.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 114.31 203.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 144.02 203.10 Td (our ) Tj ET Q q 0 0 0 rg BT 159.85 203.10 Td (market ) Tj ET Q q 0 0 0 rg BT 190.12 203.10 Td (access ) Tj ET Q q 0 0 0 rg BT 218.15 203.10 Td (in ) Tj ET Q q 0 0 0 rg BT 228.43 203.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 258.13 203.10 Td (states.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 179.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.42 179.10 Td (growth ) Tj ET Q q 0 0 0 rg BT 85.62 179.10 Td (of ) Tj ET Q q 0 0 0 rg BT 96.83 179.10 Td (MCOs, ) Tj ET Q q 0 0 0 rg BT 128.88 179.10 Td (such ) Tj ET Q q 0 0 0 rg BT 150.08 179.10 Td (as ) Tj ET Q q 0 0 0 rg BT 161.28 179.10 Td (Optum ) Tj ET Q q 0 0 0 rg BT 191.94 179.10 Td (\(UHC\), ) Tj ET Q q 0 0 0 rg BT 225.08 179.10 Td (Silver ) Tj ET Q q 0 0 0 rg BT 251.84 179.10 Td (Scripts ) Tj ET Q q 0 0 0 rg BT 282.49 179.10 Td (\(CVS\) ) Tj ET Q q 0 0 0 rg BT 311.48 179.10 Td (and ) Tj ET Q q 0 0 0 rg BT 328.79 179.10 Td (Express ) Tj ET Q q 0 0 0 rg BT 363.33 179.10 Td (Scripts ) Tj ET Q q 0 0 0 rg BT 393.98 179.10 Td (\(ESI\) ) Tj ET Q q 0 0 0 rg BT 418.51 179.10 Td (in ) Tj ET Q q 0 0 0 rg BT 429.16 179.10 Td (the ) Tj ET Q q 0 0 0 rg BT 444.25 179.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 464.91 179.10 Td (is ) Tj ET Q q 0 0 0 rg BT 474.45 179.10 Td (also ) Tj ET Q q 0 0 0 rg BT 493.44 179.10 Td (a ) Tj ET Q q 0 0 0 rg BT 500.75 179.10 Td (major ) Tj ET Q q 0 0 0 rg BT 526.95 179.10 Td (factor ) Tj ET Q q 0 0 0 rg BT 553.14 179.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.79 179.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 167.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 79.40 167.10 Td (marketplace. ) Tj ET Q q 0 0 0 rg BT 133.08 167.10 Td (Over ) Tj ET Q q 0 0 0 rg BT 155.39 167.10 Td (half ) Tj ET Q q 0 0 0 rg BT 173.26 167.10 Td (of ) Tj ET Q q 0 0 0 rg BT 183.91 167.10 Td (the ) Tj ET Q q 0 0 0 rg BT 198.45 167.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 218.55 167.10 Td (population ) Tj ET Q q 0 0 0 rg BT 263.64 167.10 Td (now ) Tj ET Q q 0 0 0 rg BT 283.19 167.10 Td (participates ) Tj ET Q q 0 0 0 rg BT 331.60 167.10 Td (in ) Tj ET Q q 0 0 0 rg BT 341.69 167.10 Td (some ) Tj ET Q q 0 0 0 rg BT 365.12 167.10 Td (version ) Tj ET Q q 0 0 0 rg BT 396.88 167.10 Td (of ) Tj ET Q q 0 0 0 rg BT 407.53 167.10 Td (managed ) Tj ET Q q 0 0 0 rg BT 445.95 167.10 Td (care. ) Tj ET Q q 0 0 0 rg BT 467.42 167.10 Td (MCOs ) Tj ET Q q 0 0 0 rg BT 496.41 167.10 Td (can ) Tj ET Q q 0 0 0 rg BT 512.61 167.10 Td (include ) Tj ET Q q 0 0 0 rg BT 544.36 167.10 Td (medical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 155.10 Td (insurance ) Tj ET Q q 0 0 0 rg BT 76.44 155.10 Td (companies, ) Tj ET Q q 0 0 0 rg BT 123.83 155.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 157.60 155.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 176.94 155.10 Td (administrators, ) Tj ET Q q 0 0 0 rg BT 238.77 155.10 Td (health-maintenance ) Tj ET Q q 0 0 0 rg BT 319.19 155.10 Td (or) Tj ET Q q 0 0 0 rg BT 327.34 155.10 Td (ganizations, ) Tj ET Q q 0 0 0 rg BT 377.50 155.10 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 417.38 155.10 Td (Part ) Tj ET Q q 0 0 0 rg BT 435.61 155.10 Td (D ) Tj ET Q q 0 0 0 rg BT 444.96 155.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 494.84 155.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 515.29 155.10 Td (plans, ) Tj ET Q q 0 0 0 rg BT 541.03 155.10 Td (alliances ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 143.10 Td (of ) Tj ET Q q 0 0 0 rg BT 47.17 143.10 Td (hospitals ) Tj ET Q q 0 0 0 rg BT 85.57 143.10 Td (and ) Tj ET Q q 0 0 0 rg BT 102.85 143.10 Td (physicians ) Tj ET Q q 0 0 0 rg BT 147.91 143.10 Td (and ) Tj ET Q q 0 0 0 rg BT 165.19 143.10 Td (other ) Tj ET Q q 0 0 0 rg BT 188.58 143.10 Td (physician ) Tj ET Q q 0 0 0 rg BT 229.75 143.10 Td (or) Tj ET Q q 0 0 0 rg BT 237.89 143.10 Td (ganizations. ) Tj ET Q q 0 0 0 rg BT 288.57 143.10 Td (Those ) Tj ET Q q 0 0 0 rg BT 315.85 143.10 Td (or) Tj ET Q q 0 0 0 rg BT 324.00 143.10 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 372.39 143.10 Td (have ) Tj ET Q q 0 0 0 rg BT 394.10 143.10 Td (been ) Tj ET Q q 0 0 0 rg BT 415.82 143.10 Td (consolidating ) Tj ET Q q 0 0 0 rg BT 472.55 143.10 Td (into ) Tj ET Q q 0 0 0 rg BT 490.95 143.10 Td (fewer) Tj ET Q q 0 0 0 rg BT 513.30 143.10 Td (, ) Tj ET Q q 0 0 0 rg BT 518.65 143.10 Td (lar) Tj ET Q q 0 0 0 rg BT 529.01 143.10 Td (ger ) Tj ET Q q 0 0 0 rg BT 544.62 143.10 Td (entities, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 131.10 Td (thus ) Tj ET Q q 0 0 0 rg BT 55.17 131.10 Td (enhancing ) Tj ET Q q 0 0 0 rg BT 98.76 131.10 Td (their ) Tj ET Q q 0 0 0 rg BT 119.59 131.10 Td (purchasing ) Tj ET Q q 0 0 0 rg BT 165.97 131.10 Td (strength ) Tj ET Q q 0 0 0 rg BT 200.68 131.10 Td (and ) Tj ET Q q 0 0 0 rg BT 217.62 131.10 Td (importance ) Tj ET Q q 0 0 0 rg BT 265.10 131.10 Td (to ) Tj ET Q q 0 0 0 rg BT 275.38 131.10 Td (us.) Tj ET Q endstream endobj 29 0 obj <> endobj 30 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (T) Tj ET Q q 0 0 0 rg BT 41.41 749.10 Td (o ) Tj ET Q q 0 0 0 rg BT 48.86 749.10 Td (successfully ) Tj ET Q q 0 0 0 rg BT 100.19 749.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 136.52 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 150.63 749.10 Td (business ) Tj ET Q q 0 0 0 rg BT 186.97 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 207.21 749.10 Td (MCOs, ) Tj ET Q q 0 0 0 rg BT 238.83 749.10 Td (we ) Tj ET Q q 0 0 0 rg BT 252.95 749.10 Td (must ) Tj ET Q q 0 0 0 rg BT 274.85 749.10 Td (often ) Tj ET Q q 0 0 0 rg BT 297.85 749.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 349.17 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 366.62 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 382.40 749.10 Td (products ) Tj ET Q q 0 0 0 rg BT 419.29 749.10 Td (of) Tj ET Q q 0 0 0 rg BT 427.44 749.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 440.99 749.10 Td (not ) Tj ET Q q 0 0 0 rg BT 456.22 749.10 Td (only ) Tj ET Q q 0 0 0 rg BT 476.45 749.10 Td (medical ) Tj ET Q q 0 0 0 rg BT 510.56 749.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 544.67 749.10 Td (but ) Tj ET Q q 0 0 0 rg BT 559.90 749.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 54.41 737.10 Td (advantages ) Tj ET Q q 0 0 0 rg BT 101.13 737.10 Td (as ) Tj ET Q q 0 0 0 rg BT 111.75 737.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 153.48 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 173.55 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 196.40 737.10 Td (forms ) Tj ET Q q 0 0 0 rg BT 222.02 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 232.65 737.10 Td (care. ) Tj ET Q q 0 0 0 rg BT 254.09 737.10 Td (Most ) Tj ET Q q 0 0 0 rg BT 276.95 737.10 Td (new ) Tj ET Q q 0 0 0 rg BT 295.91 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 332.65 737.10 Td (that ) Tj ET Q q 0 0 0 rg BT 349.94 737.10 Td (we ) Tj ET Q q 0 0 0 rg BT 363.90 737.10 Td (introduce ) Tj ET Q q 0 0 0 rg BT 403.96 737.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 440.13 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 460.20 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 483.05 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 519.78 737.10 Td (already ) Tj ET Q q 0 0 0 rg BT 551.50 737.10 Td (on ) Tj ET Q q 0 0 0 rg BT 563.80 737.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (market ) Tj ET Q q 0 0 0 rg BT 66.32 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 77.20 725.10 Td (products ) Tj ET Q q 0 0 0 rg BT 114.19 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 131.74 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 146.50 725.10 Td (later ) Tj ET Q q 0 0 0 rg BT 166.82 725.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 210.47 725.10 Td (by ) Tj ET Q q 0 0 0 rg BT 223.02 725.10 Td (competitors. ) Tj ET Q q 0 0 0 rg BT 274.72 725.10 Td (As ) Tj ET Q q 0 0 0 rg BT 288.39 725.10 Td (noted ) Tj ET Q q 0 0 0 rg BT 313.16 725.10 Td (above, ) Tj ET Q q 0 0 0 rg BT 342.09 725.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 374.07 725.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 398.84 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 413.61 725.10 Td (exempt ) Tj ET Q q 0 0 0 rg BT 445.59 725.10 Td (from ) Tj ET Q q 0 0 0 rg BT 467.58 725.10 Td (costly ) Tj ET Q q 0 0 0 rg BT 494.03 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 511.02 725.10 Td (time-consuming ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 68.24 713.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 98.83 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 109.41 713.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 161.09 713.10 Td (their ) Tj ET Q q 0 0 0 rg BT 182.23 713.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 208.91 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 226.16 713.10 Td (ef) Tj ET Q q 0 0 0 rg BT 233.75 713.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 260.98 713.10 Td (and, ) Tj ET Q q 0 0 0 rg BT 280.73 713.10 Td (as ) Tj ET Q q 0 0 0 rg BT 291.87 713.10 Td (such, ) Tj ET Q q 0 0 0 rg BT 315.51 713.10 Td (often ) Tj ET Q q 0 0 0 rg BT 338.86 713.10 Td (have ) Tj ET Q q 0 0 0 rg BT 360.55 713.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 386.13 713.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 408.94 713.10 Td (than ) Tj ET Q q 0 0 0 rg BT 428.96 713.10 Td (brand-name ) Tj ET Q q 0 0 0 rg BT 479.53 713.10 Td (drugs. ) Tj ET Q q 0 0 0 rg BT 507.06 713.10 Td (MCOs ) Tj ET Q q 0 0 0 rg BT 536.54 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 554.34 713.10 Td (focus ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 75.80 701.10 Td (on ) Tj ET Q q 0 0 0 rg BT 88.39 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 103.19 701.10 Td (immediate ) Tj ET Q q 0 0 0 rg BT 147.99 701.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 166.68 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 177.60 701.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 202.41 701.10 Td (often ) Tj ET Q q 0 0 0 rg BT 225.55 701.10 Td (favor ) Tj ET Q q 0 0 0 rg BT 249.23 701.10 Td (generics ) Tj ET Q q 0 0 0 rg BT 285.14 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 299.38 701.10 Td (this ) Tj ET Q q 0 0 0 rg BT 316.42 701.10 Td (reason. ) Tj ET Q q 0 0 0 rg BT 347.61 701.10 Td (Many ) Tj ET Q q 0 0 0 rg BT 373.52 701.10 Td (governments ) Tj ET Q q 0 0 0 rg BT 427.77 701.10 Td (also ) Tj ET Q q 0 0 0 rg BT 446.46 701.10 Td (encourage ) Tj ET Q q 0 0 0 rg BT 490.14 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 504.94 701.10 Td (use ) Tj ET Q q 0 0 0 rg BT 520.86 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 531.78 701.10 Td (generics ) Tj ET Q q 0 0 0 rg BT 567.68 701.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (alternatives ) Tj ET Q q 0 0 0 rg BT 84.40 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 94.49 689.10 Td (brand-name ) Tj ET Q q 0 0 0 rg BT 144.55 689.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 169.08 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 179.17 689.10 Td (their ) Tj ET Q q 0 0 0 rg BT 199.80 689.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 243.19 689.10 Td (programs. ) Tj ET Q q 0 0 0 rg BT 285.77 689.10 Td (Laws ) Tj ET Q q 0 0 0 rg BT 309.74 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 319.83 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 334.35 689.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 354.45 689.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 393.96 689.10 Td (allow) Tj ET Q q 0 0 0 rg BT 415.53 689.10 Td (, ) Tj ET Q q 0 0 0 rg BT 420.34 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 437.08 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 447.17 689.10 Td (many ) Tj ET Q q 0 0 0 rg BT 471.70 689.10 Td (cases ) Tj ET Q q 0 0 0 rg BT 495.11 689.10 Td (require, ) Tj ET Q q 0 0 0 rg BT 528.23 689.10 Td (pharmacists ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.83 677.10 Td (substitute ) Tj ET Q q 0 0 0 rg BT 88.21 677.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 120.68 677.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 145.95 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 164.00 677.10 Td (have ) Tj ET Q q 0 0 0 rg BT 185.92 677.10 Td (been ) Tj ET Q q 0 0 0 rg BT 207.85 677.10 Td (rated ) Tj ET Q q 0 0 0 rg BT 230.88 677.10 Td (under ) Tj ET Q q 0 0 0 rg BT 256.70 677.10 Td (government ) Tj ET Q q 0 0 0 rg BT 307.51 677.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 354.42 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 365.25 677.10 Td (be ) Tj ET Q q 0 0 0 rg BT 377.74 677.10 Td (essentially ) Tj ET Q q 0 0 0 rg BT 423.00 677.10 Td (equivalent ) Tj ET Q q 0 0 0 rg BT 467.70 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 478.52 677.10 Td (a ) Tj ET Q q 0 0 0 rg BT 486.01 677.10 Td (brand-name ) Tj ET Q q 0 0 0 rg BT 536.81 677.10 Td (drug. ) Tj ET Q q 0 0 0 rg BT 560.47 677.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (substitution ) Tj ET Q q 0 0 0 rg BT 85.17 665.10 Td (must ) Tj ET Q q 0 0 0 rg BT 107.12 665.10 Td (be ) Tj ET Q q 0 0 0 rg BT 119.06 665.10 Td (made ) Tj ET Q q 0 0 0 rg BT 143.22 665.10 Td (unless ) Tj ET Q q 0 0 0 rg BT 170.72 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 185.43 665.10 Td (prescribing ) Tj ET Q q 0 0 0 rg BT 232.92 665.10 Td (physician ) Tj ET Q q 0 0 0 rg BT 273.74 665.10 Td (expressly ) Tj ET Q q 0 0 0 rg BT 314.01 665.10 Td (forbids ) Tj ET Q q 0 0 0 rg BT 344.84 665.10 Td (it.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (Exclusion ) Tj ET Q q 0 0 0 rg BT 77.40 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 87.13 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 92.97 641.10 Td (product ) Tj ET Q q 0 0 0 rg BT 124.92 641.10 Td (from ) Tj ET Q q 0 0 0 rg BT 145.76 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 151.60 641.10 Td (formulary ) Tj ET Q q 0 0 0 rg BT 192.98 641.10 Td (can ) Tj ET Q q 0 0 0 rg BT 208.26 641.10 Td (lead ) Tj ET Q q 0 0 0 rg BT 226.32 641.10 Td (to ) Tj ET Q q 0 0 0 rg BT 235.50 641.10 Td (its ) Tj ET Q q 0 0 0 rg BT 246.35 641.10 Td (sharply ) Tj ET Q q 0 0 0 rg BT 277.19 641.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 310.23 641.10 Td (usage ) Tj ET Q q 0 0 0 rg BT 334.40 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 343.58 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 357.20 641.10 Td (MCO ) Tj ET Q q 0 0 0 rg BT 381.39 641.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 410.00 641.10 Td (population. ) Tj ET Q q 0 0 0 rg BT 456.67 641.10 Td (Consequently) Tj ET Q q 0 0 0 rg BT 511.02 641.10 Td (, ) Tj ET Q q 0 0 0 rg BT 514.92 641.10 Td (pharmaceutical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 81.29 629.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 117.68 629.10 Td (aggressively ) Tj ET Q q 0 0 0 rg BT 170.19 629.10 Td (to ) Tj ET Q q 0 0 0 rg BT 180.49 629.10 Td (have ) Tj ET Q q 0 0 0 rg BT 201.89 629.10 Td (their ) Tj ET Q q 0 0 0 rg BT 222.73 629.10 Td (products ) Tj ET Q q 0 0 0 rg BT 259.69 629.10 Td (included. ) Tj ET Q q 0 0 0 rg BT 298.97 629.10 Td (Where ) Tj ET Q q 0 0 0 rg BT 328.13 629.10 Td (possible, ) Tj ET Q q 0 0 0 rg BT 365.94 629.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 411.22 629.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 447.61 629.10 Td (for ) Tj ET Q q 0 0 0 rg BT 461.80 629.10 Td (inclusion ) Tj ET Q q 0 0 0 rg BT 500.98 629.10 Td (based ) Tj ET Q q 0 0 0 rg BT 526.27 629.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 548.80 629.10 Td (unique ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (features ) Tj ET Q q 0 0 0 rg BT 70.05 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 80.78 617.10 Td (their ) Tj ET Q q 0 0 0 rg BT 101.50 617.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 140.84 617.10 Td (such ) Tj ET Q q 0 0 0 rg BT 161.57 617.10 Td (as ) Tj ET Q q 0 0 0 rg BT 172.30 617.10 Td (greater ) Tj ET Q q 0 0 0 rg BT 202.45 617.10 Td (ef) Tj ET Q q 0 0 0 rg BT 210.04 617.10 Td (ficacy) Tj ET Q q 0 0 0 rg BT 233.81 617.10 Td (, ) Tj ET Q q 0 0 0 rg BT 238.71 617.10 Td (better ) Tj ET Q q 0 0 0 rg BT 263.88 617.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 293.49 617.10 Td (ease ) Tj ET Q q 0 0 0 rg BT 313.10 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 323.83 617.10 Td (use ) Tj ET Q q 0 0 0 rg BT 339.56 617.10 Td (or ) Tj ET Q q 0 0 0 rg BT 350.29 617.10 Td (fewer ) Tj ET Q q 0 0 0 rg BT 375.45 617.10 Td (side ) Tj ET Q q 0 0 0 rg BT 393.95 617.10 Td (ef) Tj ET Q q 0 0 0 rg BT 401.54 617.10 Td (fects. ) Tj ET Q q 0 0 0 rg BT 424.79 617.10 Td (A) Tj ET Q q 0 0 0 rg BT 431.46 617.10 Td ( ) Tj ET Q q 0 0 0 rg BT 433.86 617.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 459.03 617.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 489.19 617.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 507.70 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 518.43 617.10 Td (therapy ) Tj ET Q q 0 0 0 rg BT 550.81 617.10 Td (is ) Tj ET Q q 0 0 0 rg BT 559.88 617.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (an ) Tj ET Q q 0 0 0 rg BT 48.32 605.10 Td (important ) Tj ET Q q 0 0 0 rg BT 90.08 605.10 Td (factor) Tj ET Q q 0 0 0 rg BT 112.85 605.10 Td (. ) Tj ET Q q 0 0 0 rg BT 118.23 605.10 Td (Products ) Tj ET Q q 0 0 0 rg BT 156.11 605.10 Td (that ) Tj ET Q q 0 0 0 rg BT 173.98 605.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 225.74 605.10 Td (fewer ) Tj ET Q q 0 0 0 rg BT 251.38 605.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 298.68 605.10 Td (advantages ) Tj ET Q q 0 0 0 rg BT 345.98 605.10 Td (must ) Tj ET Q q 0 0 0 rg BT 368.31 605.10 Td (compete ) Tj ET Q q 0 0 0 rg BT 405.06 605.10 Td (for ) Tj ET Q q 0 0 0 rg BT 419.60 605.10 Td (inclusion ) Tj ET Q q 0 0 0 rg BT 459.15 605.10 Td (based ) Tj ET Q q 0 0 0 rg BT 484.80 605.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 524.89 605.10 Td (on ) Tj ET Q q 0 0 0 rg BT 537.77 605.10 Td (price. ) Tj ET Q q 0 0 0 rg BT 562.93 605.10 Td (W) Tj ET Q q 0 0 0 rg BT 571.57 605.10 Td (e ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (have ) Tj ET Q q 0 0 0 rg BT 57.38 593.10 Td (been ) Tj ET Q q 0 0 0 rg BT 78.75 593.10 Td (generally) Tj ET Q q 0 0 0 rg BT 115.31 593.10 Td (, ) Tj ET Q q 0 0 0 rg BT 120.31 593.10 Td (although ) Tj ET Q q 0 0 0 rg BT 157.80 593.10 Td (not ) Tj ET Q q 0 0 0 rg BT 173.08 593.10 Td (universally) Tj ET Q q 0 0 0 rg BT 216.86 593.10 Td (, ) Tj ET Q q 0 0 0 rg BT 221.86 593.10 Td (successful ) Tj ET Q q 0 0 0 rg BT 265.46 593.10 Td (in ) Tj ET Q q 0 0 0 rg BT 275.74 593.10 Td (having ) Tj ET Q q 0 0 0 rg BT 305.46 593.10 Td (our ) Tj ET Q q 0 0 0 rg BT 321.29 593.10 Td (major ) Tj ET Q q 0 0 0 rg BT 347.11 593.10 Td (products ) Tj ET Q q 0 0 0 rg BT 384.05 593.10 Td (included ) Tj ET Q q 0 0 0 rg BT 420.99 593.10 Td (on ) Tj ET Q q 0 0 0 rg BT 433.49 593.10 Td (MCO ) Tj ET Q q 0 0 0 rg BT 458.77 593.10 Td (formularies.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.37 569.10 Td (many ) Tj ET Q q 0 0 0 rg BT 70.62 569.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 104.31 569.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 135.23 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 149.49 569.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 171.81 569.10 Td (we ) Tj ET Q q 0 0 0 rg BT 185.50 569.10 Td (operate ) Tj ET Q q 0 0 0 rg BT 216.96 569.10 Td (in ) Tj ET Q q 0 0 0 rg BT 226.78 569.10 Td (an ) Tj ET Q q 0 0 0 rg BT 238.25 569.10 Td (environment ) Tj ET Q q 0 0 0 rg BT 290.83 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 301.20 569.10 Td (government-mandated, ) Tj ET Q q 0 0 0 rg BT 395.70 569.10 Td (cost-containment ) Tj ET Q q 0 0 0 rg BT 466.60 569.10 Td (programs. ) Tj ET Q q 0 0 0 rg BT 508.91 569.10 Td (In ) Tj ET Q q 0 0 0 rg BT 519.27 569.10 Td (these ) Tj ET Q q 0 0 0 rg BT 541.85 569.10 Td (markets, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (a ) Tj ET Q q 0 0 0 rg BT 42.77 557.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 87.31 557.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 118.53 557.10 Td (of ) Tj ET Q q 0 0 0 rg BT 129.19 557.10 Td (funding ) Tj ET Q q 0 0 0 rg BT 162.63 557.10 Td (for ) Tj ET Q q 0 0 0 rg BT 176.63 557.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 220.04 557.10 Td (services ) Tj ET Q q 0 0 0 rg BT 254.57 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 271.34 557.10 Td (the ) Tj ET Q q 0 0 0 rg BT 285.89 557.10 Td (determination ) Tj ET Q q 0 0 0 rg BT 343.76 557.10 Td (of ) Tj ET Q q 0 0 0 rg BT 354.42 557.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 385.08 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 401.85 557.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 464.16 557.10 Td (for ) Tj ET Q q 0 0 0 rg BT 478.15 557.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 541.56 557.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (are ) Tj ET Q q 0 0 0 rg BT 51.25 545.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 82.62 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 93.44 545.10 Td (government ) Tj ET Q q 0 0 0 rg BT 144.25 545.10 Td (control. ) Tj ET Q q 0 0 0 rg BT 177.45 545.10 Td (As ) Tj ET Q q 0 0 0 rg BT 191.61 545.10 Td (a ) Tj ET Q q 0 0 0 rg BT 199.09 545.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 226.85 545.10 Td (our ) Tj ET Q q 0 0 0 rg BT 243.23 545.10 Td (products ) Tj ET Q q 0 0 0 rg BT 280.71 545.10 Td (may ) Tj ET Q q 0 0 0 rg BT 300.97 545.10 Td (face ) Tj ET Q q 0 0 0 rg BT 320.66 545.10 Td (restricted ) Tj ET Q q 0 0 0 rg BT 360.91 545.10 Td (access ) Tj ET Q q 0 0 0 rg BT 389.49 545.10 Td (by ) Tj ET Q q 0 0 0 rg BT 402.53 545.10 Td (both ) Tj ET Q q 0 0 0 rg BT 423.36 545.10 Td (public ) Tj ET Q q 0 0 0 rg BT 451.40 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 468.88 545.10 Td (private ) Tj ET Q q 0 0 0 rg BT 499.69 545.10 Td (payers ) Tj ET Q q 0 0 0 rg BT 528.83 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 546.31 545.10 Td (may ) Tj ET Q q 0 0 0 rg BT 566.57 545.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 66.07 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 75.60 533.10 Td (assessments ) Tj ET Q q 0 0 0 rg BT 125.67 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 135.75 533.10 Td (comparative ) Tj ET Q q 0 0 0 rg BT 186.92 533.10 Td (value ) Tj ET Q q 0 0 0 rg BT 210.32 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 226.51 533.10 Td (ef) Tj ET Q q 0 0 0 rg BT 234.09 533.10 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 280.26 533.10 Td (against ) Tj ET Q q 0 0 0 rg BT 310.34 533.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 359.29 533.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 397.98 533.10 Td (Several ) Tj ET Q q 0 0 0 rg BT 429.71 533.10 Td (governments ) Tj ET Q q 0 0 0 rg BT 483.11 533.10 Td (have ) Tj ET Q q 0 0 0 rg BT 503.74 533.10 Td (placed ) Tj ET Q q 0 0 0 rg BT 531.58 533.10 Td (restrictions ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (on ) Tj ET Q q 0 0 0 rg BT 48.77 521.10 Td (physician ) Tj ET Q q 0 0 0 rg BT 89.87 521.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 140.41 521.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 166.50 521.10 Td (and ) Tj ET Q q 0 0 0 rg BT 183.71 521.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 213.70 521.10 Td (reimbursements, ) Tj ET Q q 0 0 0 rg BT 282.84 521.10 Td (emphasized ) Tj ET Q q 0 0 0 rg BT 332.82 521.10 Td (greater ) Tj ET Q q 0 0 0 rg BT 363.34 521.10 Td (use ) Tj ET Q q 0 0 0 rg BT 379.45 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 390.55 521.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 422.75 521.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 447.74 521.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 476.06 521.10 Td (enacted ) Tj ET Q q 0 0 0 rg BT 509.36 521.10 Td (across-the-board ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (price ) Tj ET Q q 0 0 0 rg BT 58.71 509.10 Td (cuts ) Tj ET Q q 0 0 0 rg BT 77.54 509.10 Td (as ) Tj ET Q q 0 0 0 rg BT 88.59 509.10 Td (methods ) Tj ET Q q 0 0 0 rg BT 125.20 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 136.25 509.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 155.08 509.10 Td (control. ) Tj ET Q q 0 0 0 rg BT 188.63 509.10 Td (In ) Tj ET Q q 0 0 0 rg BT 199.68 509.10 Td (most ) Tj ET Q q 0 0 0 rg BT 221.85 509.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 237.90 509.10 Td (countries, ) Tj ET Q q 0 0 0 rg BT 279.78 509.10 Td (for ) Tj ET Q q 0 0 0 rg BT 294.16 509.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 333.26 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 348.20 509.10 Td (government ) Tj ET Q q 0 0 0 rg BT 398.68 509.10 Td (regulates ) Tj ET Q q 0 0 0 rg BT 437.50 509.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 468.55 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 479.60 509.10 Td (a ) Tj ET Q q 0 0 0 rg BT 486.76 509.10 Td (new ) Tj ET Q q 0 0 0 rg BT 506.14 509.10 Td (product ) Tj ET Q q 0 0 0 rg BT 539.41 509.10 Td (at ) Tj ET Q q 0 0 0 rg BT 549.35 509.10 Td (launch ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (often ) Tj ET Q q 0 0 0 rg BT 59.20 497.10 Td (through ) Tj ET Q q 0 0 0 rg BT 92.96 497.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 118.37 497.10 Td (price ) Tj ET Q q 0 0 0 rg BT 141.01 497.10 Td (controls, ) Tj ET Q q 0 0 0 rg BT 178.37 497.10 Td (international ) Tj ET Q q 0 0 0 rg BT 231.56 497.10 Td (price ) Tj ET Q q 0 0 0 rg BT 254.20 497.10 Td (comparisons, ) Tj ET Q q 0 0 0 rg BT 309.89 497.10 Td (controlling ) Tj ET Q q 0 0 0 rg BT 356.43 497.10 Td (profits ) Tj ET Q q 0 0 0 rg BT 385.18 497.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 413.38 497.10 Td (reference ) Tj ET Q q 0 0 0 rg BT 453.21 497.10 Td (pricing. ) Tj ET Q q 0 0 0 rg BT 486.69 497.10 Td (In ) Tj ET Q q 0 0 0 rg BT 497.67 497.10 Td (other ) Tj ET Q q 0 0 0 rg BT 520.87 497.10 Td (markets, ) Tj ET Q q 0 0 0 rg BT 557.67 497.10 Td (such ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (as ) Tj ET Q q 0 0 0 rg BT 46.37 485.10 Td (Germany) Tj ET Q q 0 0 0 rg BT 82.93 485.10 Td (, ) Tj ET Q q 0 0 0 rg BT 87.47 485.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.73 485.10 Td (government ) Tj ET Q q 0 0 0 rg BT 151.54 485.10 Td (does ) Tj ET Q q 0 0 0 rg BT 171.92 485.10 Td (not ) Tj ET Q q 0 0 0 rg BT 186.74 485.10 Td (set ) Tj ET Q q 0 0 0 rg BT 199.89 485.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 230.26 485.10 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 276.73 485.10 Td (at ) Tj ET Q q 0 0 0 rg BT 286.00 485.10 Td (launch, ) Tj ET Q q 0 0 0 rg BT 317.19 485.10 Td (but ) Tj ET Q q 0 0 0 rg BT 332.02 485.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 362.38 485.10 Td (freedom ) Tj ET Q q 0 0 0 rg BT 397.74 485.10 Td (is ) Tj ET Q q 0 0 0 rg BT 406.46 485.10 Td (subsequently ) Tj ET Q q 0 0 0 rg BT 460.72 485.10 Td (limited. ) Tj ET Q q 0 0 0 rg BT 493.59 485.10 Td (Companies ) Tj ET Q q 0 0 0 rg BT 540.63 485.10 Td (may ) Tj ET Q q 0 0 0 rg BT 559.89 485.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (face ) Tj ET Q q 0 0 0 rg BT 55.21 473.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 99.98 473.10 Td (delays ) Tj ET Q q 0 0 0 rg BT 128.08 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 138.42 473.10 Td (market ) Tj ET Q q 0 0 0 rg BT 168.75 473.10 Td (access ) Tj ET Q q 0 0 0 rg BT 196.84 473.10 Td (for ) Tj ET Q q 0 0 0 rg BT 211.06 473.10 Td (new ) Tj ET Q q 0 0 0 rg BT 230.28 473.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 269.78 473.10 Td (mainly ) Tj ET Q q 0 0 0 rg BT 300.12 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 310.45 473.10 Td (France, ) Tj ET Q q 0 0 0 rg BT 342.72 473.10 Td (Spain, ) Tj ET Q q 0 0 0 rg BT 370.56 473.10 Td (Italy ) Tj ET Q q 0 0 0 rg BT 391.45 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 408.44 473.10 Td (Belgium, ) Tj ET Q q 0 0 0 rg BT 447.95 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 464.95 473.10 Td (more ) Tj ET Q q 0 0 0 rg BT 488.05 473.10 Td (than ) Tj ET Q q 0 0 0 rg BT 507.83 473.10 Td (a ) Tj ET Q q 0 0 0 rg BT 514.83 473.10 Td (year ) Tj ET Q q 0 0 0 rg BT 534.60 473.10 Td (can ) Tj ET Q q 0 0 0 rg BT 551.03 473.10 Td (elapse ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (before ) Tj ET Q q 0 0 0 rg BT 64.12 461.10 Td (new ) Tj ET Q q 0 0 0 rg BT 83.35 461.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 126.47 461.10 Td (become ) Tj ET Q q 0 0 0 rg BT 160.15 461.10 Td (available ) Tj ET Q q 0 0 0 rg BT 198.81 461.10 Td (on ) Tj ET Q q 0 0 0 rg BT 211.39 461.10 Td (some ) Tj ET Q q 0 0 0 rg BT 235.08 461.10 Td (national ) Tj ET Q q 0 0 0 rg BT 269.87 461.10 Td (markets. ) Tj ET Q q 0 0 0 rg BT 306.03 461.10 Td (Additionally) Tj ET Q q 0 0 0 rg BT 355.93 461.10 Td (, ) Tj ET Q q 0 0 0 rg BT 361.01 461.10 Td (member ) Tj ET Q q 0 0 0 rg BT 396.35 461.10 Td (states ) Tj ET Q q 0 0 0 rg BT 421.15 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 432.06 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 446.85 461.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 462.76 461.10 Td (have ) Tj ET Q q 0 0 0 rg BT 484.22 461.10 Td (regularly ) Tj ET Q q 0 0 0 rg BT 522.89 461.10 Td (imposed ) Tj ET Q q 0 0 0 rg BT 559.35 461.10 Td (new ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (or ) Tj ET Q q 0 0 0 rg BT 46.59 449.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 88.84 449.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 107.21 449.10 Td (containment ) Tj ET Q q 0 0 0 rg BT 158.90 449.10 Td (measures ) Tj ET Q q 0 0 0 rg BT 198.37 449.10 Td (for ) Tj ET Q q 0 0 0 rg BT 212.29 449.10 Td (pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 279.52 449.10 Td (such ) Tj ET Q q 0 0 0 rg BT 300.11 449.10 Td (as ) Tj ET Q q 0 0 0 rg BT 310.70 449.10 Td (volume ) Tj ET Q q 0 0 0 rg BT 342.95 449.10 Td (discounts, ) Tj ET Q q 0 0 0 rg BT 385.49 449.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 403.86 449.10 Td (caps, ) Tj ET Q q 0 0 0 rg BT 426.39 449.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 444.76 449.10 Td (sharing ) Tj ET Q q 0 0 0 rg BT 476.46 449.10 Td (for ) Tj ET Q q 0 0 0 rg BT 490.38 449.10 Td (increases ) Tj ET Q q 0 0 0 rg BT 529.29 449.10 Td (in ) Tj ET Q q 0 0 0 rg BT 539.33 449.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 567.68 449.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 58.52 437.10 Td (year ) Tj ET Q q 0 0 0 rg BT 78.81 437.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 101.89 437.10 Td (for ) Tj ET Q q 0 0 0 rg BT 116.63 437.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 160.26 437.10 Td (products ) Tj ET Q q 0 0 0 rg BT 197.78 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 209.19 437.10 Td (aggregated ) Tj ET Q q 0 0 0 rg BT 256.14 437.10 Td (market ) Tj ET Q q 0 0 0 rg BT 286.98 437.10 Td (level ) Tj ET Q q 0 0 0 rg BT 309.50 437.10 Td (spending, ) Tj ET Q q 0 0 0 rg BT 351.19 437.10 Td (outcome-based ) Tj ET Q q 0 0 0 rg BT 414.80 437.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 446.21 437.10 Td (schemes ) Tj ET Q q 0 0 0 rg BT 483.16 437.10 Td (and ) Tj ET Q q 0 0 0 rg BT 500.68 437.10 Td (free ) Tj ET Q q 0 0 0 rg BT 519.30 437.10 Td (products ) Tj ET Q q 0 0 0 rg BT 556.82 437.10 Td (for ) Tj ET Q q 0 0 0 rg BT 571.56 437.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 66.92 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 77.29 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 91.55 425.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 129.12 425.10 Td (therapy ) Tj ET Q q 0 0 0 rg BT 161.14 425.10 Td (period. ) Tj ET Q q 0 0 0 rg BT 191.22 425.10 Td (In ) Tj ET Q q 0 0 0 rg BT 201.59 425.10 Td (recent ) Tj ET Q q 0 0 0 rg BT 228.05 425.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 253.69 425.10 Td (Italy) Tj ET Q q 0 0 0 rg BT 271.36 425.10 Td (, ) Tj ET Q q 0 0 0 rg BT 275.90 425.10 Td (for ) Tj ET Q q 0 0 0 rg BT 289.60 425.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 328.01 425.10 Td (has ) Tj ET Q q 0 0 0 rg BT 343.38 425.10 Td (imposed ) Tj ET Q q 0 0 0 rg BT 379.30 425.10 Td (mandatory ) Tj ET Q q 0 0 0 rg BT 424.10 425.10 Td (price ) Tj ET Q q 0 0 0 rg BT 446.13 425.10 Td (decreases. ) Tj ET Q q 0 0 0 rg BT 488.82 425.10 Td (The ) Tj ET Q q 0 0 0 rg BT 506.41 425.10 Td (existence ) Tj ET Q q 0 0 0 rg BT 545.65 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 556.01 425.10 Td (price ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (dif) Tj ET Q q 0 0 0 rg BT 46.93 413.10 Td (ferentials ) Tj ET Q q 0 0 0 rg BT 86.63 413.10 Td (within ) Tj ET Q q 0 0 0 rg BT 114.69 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 129.40 413.10 Td (EU ) Tj ET Q q 0 0 0 rg BT 145.23 413.10 Td (due ) Tj ET Q q 0 0 0 rg BT 162.17 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 172.45 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 187.17 413.10 Td (dif) Tj ET Q q 0 0 0 rg BT 198.09 413.10 Td (ferent ) Tj ET Q q 0 0 0 rg BT 223.91 413.10 Td (national ) Tj ET Q q 0 0 0 rg BT 258.62 413.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 289.45 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 306.39 413.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 368.87 413.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 389.70 413.10 Td (leads ) Tj ET Q q 0 0 0 rg BT 412.74 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 423.02 413.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 467.73 413.10 Td (parallel ) Tj ET Q q 0 0 0 rg BT 500.21 413.10 Td (trade ) Tj ET Q q 0 0 0 rg BT 522.70 413.10 Td (flows.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (Government Regulation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.07 365.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 117.67 365.10 Td (industry ) Tj ET Q q 0 0 0 rg BT 152.97 365.10 Td (is ) Tj ET Q q 0 0 0 rg BT 162.17 365.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 193.02 365.10 Td (to ) Tj ET Q q 0 0 0 rg BT 203.32 365.10 Td (extensive ) Tj ET Q q 0 0 0 rg BT 243.61 365.10 Td (global ) Tj ET Q q 0 0 0 rg BT 271.13 365.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 318.08 365.10 Td (by ) Tj ET Q q 0 0 0 rg BT 330.61 365.10 Td (regional, ) Tj ET Q q 0 0 0 rg BT 368.40 365.10 Td (country) Tj ET Q q 0 0 0 rg BT 398.29 365.10 Td (, ) Tj ET Q q 0 0 0 rg BT 403.32 365.10 Td (state ) Tj ET Q q 0 0 0 rg BT 424.17 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 441.13 365.10 Td (local ) Tj ET Q q 0 0 0 rg BT 463.09 365.10 Td (agencies. ) Tj ET Q q 0 0 0 rg BT 502.36 365.10 Td (The ) Tj ET Q q 0 0 0 rg BT 520.43 365.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 552.94 365.10 Td (Food, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (Drug, ) Tj ET Q q 0 0 0 rg BT 61.11 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 77.60 353.10 Td (Cosmetic ) Tj ET Q q 0 0 0 rg BT 116.98 353.10 Td (Act, ) Tj ET Q q 0 0 0 rg BT 135.97 353.10 Td (other ) Tj ET Q q 0 0 0 rg BT 158.57 353.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 190.61 353.10 Td (statutes ) Tj ET Q q 0 0 0 rg BT 222.67 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 239.16 353.10 Td (regulations, ) Tj ET Q q 0 0 0 rg BT 288.15 353.10 Td (various ) Tj ET Q q 0 0 0 rg BT 319.64 353.10 Td (state ) Tj ET Q q 0 0 0 rg BT 340.02 353.10 Td (statutes ) Tj ET Q q 0 0 0 rg BT 372.07 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 388.57 353.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 435.06 353.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 478.22 353.10 Td (newly ) Tj ET Q q 0 0 0 rg BT 504.71 353.10 Td (enacted ) Tj ET Q q 0 0 0 rg BT 537.30 353.10 Td (state ) Tj ET Q q 0 0 0 rg BT 557.68 353.10 Td (laws ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (regulating ) Tj ET Q q 0 0 0 rg BT 79.10 341.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 99.98 341.10 Td (price ) Tj ET Q q 0 0 0 rg BT 122.53 341.10 Td (transparency ) Tj ET Q q 0 0 0 rg BT 176.17 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 193.16 341.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 214.05 341.10 Td (spending\), ) Tj ET Q q 0 0 0 rg BT 258.54 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 275.54 341.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 296.42 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 313.42 341.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 360.41 341.10 Td (of ) Tj ET Q q 0 0 0 rg BT 371.29 341.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 402.73 341.10 Td (governments ) Tj ET Q q 0 0 0 rg BT 456.94 341.10 Td (govern ) Tj ET Q q 0 0 0 rg BT 487.26 341.10 Td (to ) Tj ET Q q 0 0 0 rg BT 497.60 341.10 Td (varying ) Tj ET Q q 0 0 0 rg BT 530.70 341.10 Td (degrees ) Tj ET Q q 0 0 0 rg BT 563.79 341.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (testing, ) Tj ET Q q 0 0 0 rg BT 67.79 329.10 Td (approval, ) Tj ET Q q 0 0 0 rg BT 107.90 329.10 Td (production, ) Tj ET Q q 0 0 0 rg BT 156.35 329.10 Td (labeling, ) Tj ET Q q 0 0 0 rg BT 193.69 329.10 Td (distribution, ) Tj ET Q q 0 0 0 rg BT 244.92 329.10 Td (post-market ) Tj ET Q q 0 0 0 rg BT 295.31 329.10 Td (surveillance, ) Tj ET Q q 0 0 0 rg BT 348.75 329.10 Td (advertising, ) Tj ET Q q 0 0 0 rg BT 398.30 329.10 Td (dissemination ) Tj ET Q q 0 0 0 rg BT 456.48 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 467.44 329.10 Td (information ) Tj ET Q q 0 0 0 rg BT 517.27 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 534.33 329.10 Td (promotion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.51 317.10 Td (our ) Tj ET Q q 0 0 0 rg BT 62.01 317.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 100.97 317.10 Td (The ) Tj ET Q q 0 0 0 rg BT 118.69 317.10 Td (lengthy ) Tj ET Q q 0 0 0 rg BT 150.87 317.10 Td (process ) Tj ET Q q 0 0 0 rg BT 183.03 317.10 Td (of ) Tj ET Q q 0 0 0 rg BT 193.54 317.10 Td (laboratory ) Tj ET Q q 0 0 0 rg BT 236.81 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 253.43 317.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 285.03 317.10 Td (testing, ) Tj ET Q q 0 0 0 rg BT 316.37 317.10 Td (data ) Tj ET Q q 0 0 0 rg BT 335.21 317.10 Td (analysis, ) Tj ET Q q 0 0 0 rg BT 372.10 317.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 435.09 317.10 Td (development ) Tj ET Q q 0 0 0 rg BT 488.91 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 505.53 317.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 548.80 317.10 Td (review ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 77.44 305.10 Td (for ) Tj ET Q q 0 0 0 rg BT 91.68 305.10 Td (required ) Tj ET Q q 0 0 0 rg BT 127.57 305.10 Td (governmental ) Tj ET Q q 0 0 0 rg BT 185.13 305.10 Td (approvals ) Tj ET Q q 0 0 0 rg BT 226.58 305.10 Td (is ) Tj ET Q q 0 0 0 rg BT 235.82 305.10 Td (extremely ) Tj ET Q q 0 0 0 rg BT 278.38 305.10 Td (costly ) Tj ET Q q 0 0 0 rg BT 304.84 305.10 Td (and ) Tj ET Q q 0 0 0 rg BT 321.86 305.10 Td (can ) Tj ET Q q 0 0 0 rg BT 338.31 305.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 390.88 305.10 Td (delay ) Tj ET Q q 0 0 0 rg BT 415.11 305.10 Td (product ) Tj ET Q q 0 0 0 rg BT 448.23 305.10 Td (introductions ) Tj ET Q q 0 0 0 rg BT 503.58 305.10 Td (in ) Tj ET Q q 0 0 0 rg BT 513.93 305.10 Td (a ) Tj ET Q q 0 0 0 rg BT 520.95 305.10 Td (given ) Tj ET Q q 0 0 0 rg BT 545.74 305.10 Td (market. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (Promotion, ) Tj ET Q q 0 0 0 rg BT 83.13 293.10 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 128.57 293.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 189.28 293.10 Td (and ) Tj ET Q q 0 0 0 rg BT 206.12 293.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 254.63 293.10 Td (of ) Tj ET Q q 0 0 0 rg BT 265.36 293.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 328.83 293.10 Td (products ) Tj ET Q q 0 0 0 rg BT 365.67 293.10 Td (are ) Tj ET Q q 0 0 0 rg BT 380.28 293.10 Td (extensively ) Tj ET Q q 0 0 0 rg BT 428.22 293.10 Td (regulated ) Tj ET Q q 0 0 0 rg BT 467.82 293.10 Td (in ) Tj ET Q q 0 0 0 rg BT 478.00 293.10 Td (all ) Tj ET Q q 0 0 0 rg BT 490.40 293.10 Td (major ) Tj ET Q q 0 0 0 rg BT 516.12 293.10 Td (world ) Tj ET Q q 0 0 0 rg BT 541.85 293.10 Td (markets. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.67 281.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 86.29 281.10 Td (our ) Tj ET Q q 0 0 0 rg BT 102.96 281.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 147.96 281.10 Td (are ) Tj ET Q q 0 0 0 rg BT 163.51 281.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 195.18 281.10 Td (to ) Tj ET Q q 0 0 0 rg BT 206.31 281.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 244.08 281.10 Td (Federal, ) Tj ET Q q 0 0 0 rg BT 279.91 281.10 Td (state, ) Tj ET Q q 0 0 0 rg BT 304.08 281.10 Td (local, ) Tj ET Q q 0 0 0 rg BT 329.36 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 347.14 281.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 379.36 281.10 Td (environmental ) Tj ET Q q 0 0 0 rg BT 440.46 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 458.25 281.10 Td (occupational ) Tj ET Q q 0 0 0 rg BT 512.68 281.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 539.90 281.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 561.57 281.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (regulations. ) Tj ET Q q 0 0 0 rg BT 85.59 269.10 Td (W) Tj ET Q q 0 0 0 rg BT 94.23 269.10 Td (e ) Tj ET Q q 0 0 0 rg BT 101.53 269.10 Td (anticipate ) Tj ET Q q 0 0 0 rg BT 143.27 269.10 Td (that ) Tj ET Q q 0 0 0 rg BT 161.13 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 176.21 269.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 197.40 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 214.71 269.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 262.01 269.10 Td (af) Tj ET Q q 0 0 0 rg BT 269.59 269.10 Td (fecting ) Tj ET Q q 0 0 0 rg BT 300.22 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 315.30 269.10 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 368.14 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 385.44 269.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 403.86 269.10 Td (of ) Tj ET Q q 0 0 0 rg BT 415.05 269.10 Td (current ) Tj ET Q q 0 0 0 rg BT 446.23 269.10 Td (products ) Tj ET Q q 0 0 0 rg BT 483.54 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 500.84 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 515.92 269.10 Td (introduction ) Tj ET Q q 0 0 0 rg BT 567.67 269.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (new ) Tj ET Q q 0 0 0 rg BT 54.29 257.10 Td (products ) Tj ET Q q 0 0 0 rg BT 90.35 257.10 Td (will ) Tj ET Q q 0 0 0 rg BT 107.54 257.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 143.60 257.10 Td (to ) Tj ET Q q 0 0 0 rg BT 153.00 257.10 Td (require ) Tj ET Q q 0 0 0 rg BT 182.95 257.10 Td (substantial ) Tj ET Q q 0 0 0 rg BT 227.35 257.10 Td (scientific ) Tj ET Q q 0 0 0 rg BT 265.63 257.10 Td (and ) Tj ET Q q 0 0 0 rg BT 281.69 257.10 Td (technical ) Tj ET Q q 0 0 0 rg BT 319.41 257.10 Td (ef) Tj ET Q q 0 0 0 rg BT 327.00 257.10 Td (fort, ) Tj ET Q q 0 0 0 rg BT 345.56 257.10 Td (time ) Tj ET Q q 0 0 0 rg BT 364.96 257.10 Td (and ) Tj ET Q q 0 0 0 rg BT 381.03 257.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 414.86 257.10 Td (as ) Tj ET Q q 0 0 0 rg BT 424.82 257.10 Td (well ) Tj ET Q q 0 0 0 rg BT 443.67 257.10 Td (as ) Tj ET Q q 0 0 0 rg BT 453.62 257.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 497.46 257.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 525.74 257.10 Td (investments.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.93 233.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 73.39 233.10 Td ( ) Tj ET Q q 0 0 0 rg BT 75.78 233.10 Td (is ) Tj ET Q q 0 0 0 rg BT 84.83 233.10 Td (of ) Tj ET Q q 0 0 0 rg BT 95.55 233.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 136.25 233.10 Td (importance ) Tj ET Q q 0 0 0 rg BT 183.62 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 193.78 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 208.39 233.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 228.56 233.10 Td (It ) Tj ET Q q 0 0 0 rg BT 237.05 233.10 Td (has ) Tj ET Q q 0 0 0 rg BT 252.77 233.10 Td (jurisdiction ) Tj ET Q q 0 0 0 rg BT 300.71 233.10 Td (over ) Tj ET Q q 0 0 0 rg BT 320.87 233.10 Td (virtually ) Tj ET Q q 0 0 0 rg BT 357.14 233.10 Td (all ) Tj ET Q q 0 0 0 rg BT 369.52 233.10 Td (of ) Tj ET Q q 0 0 0 rg BT 380.24 233.10 Td (our ) Tj ET Q q 0 0 0 rg BT 395.96 233.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 434.44 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 451.27 233.10 Td (imposes ) Tj ET Q q 0 0 0 rg BT 486.43 233.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 541.02 233.10 Td (covering ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.44 221.10 Td (testing, ) Tj ET Q q 0 0 0 rg BT 83.83 221.10 Td (safety) Tj ET Q q 0 0 0 rg BT 107.06 221.10 Td (, ) Tj ET Q q 0 0 0 rg BT 112.79 221.10 Td (ef) Tj ET Q q 0 0 0 rg BT 120.38 221.10 Td (fectiveness, ) Tj ET Q q 0 0 0 rg BT 170.53 221.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 234.56 221.10 Td (labeling, ) Tj ET Q q 0 0 0 rg BT 272.50 221.10 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 318.77 221.10 Td (advertising ) Tj ET Q q 0 0 0 rg BT 366.43 221.10 Td (and ) Tj ET Q q 0 0 0 rg BT 384.10 221.10 Td (post-marketing ) Tj ET Q q 0 0 0 rg BT 447.87 221.10 Td (surveillance ) Tj ET Q q 0 0 0 rg BT 499.40 221.10 Td (of ) Tj ET Q q 0 0 0 rg BT 510.96 221.10 Td (our ) Tj ET Q q 0 0 0 rg BT 527.52 221.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 567.68 221.10 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (many ) Tj ET Q q 0 0 0 rg BT 60.65 209.10 Td (cases, ) Tj ET Q q 0 0 0 rg BT 86.67 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.32 209.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 120.77 209.10 Td ( ) Tj ET Q q 0 0 0 rg BT 123.20 209.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 177.83 209.10 Td (have ) Tj ET Q q 0 0 0 rg BT 199.13 209.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 239.32 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 253.96 209.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 286.38 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 297.14 209.10 Td (time ) Tj ET Q q 0 0 0 rg BT 317.34 209.10 Td (and ) Tj ET Q q 0 0 0 rg BT 334.21 209.10 Td (money ) Tj ET Q q 0 0 0 rg BT 363.86 209.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 405.15 209.10 Td (to ) Tj ET Q q 0 0 0 rg BT 415.36 209.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 449.44 209.10 Td (new ) Tj ET Q q 0 0 0 rg BT 468.53 209.10 Td (products ) Tj ET Q q 0 0 0 rg BT 505.40 209.10 Td (and ) Tj ET Q q 0 0 0 rg BT 522.26 209.10 Td (bring ) Tj ET Q q 0 0 0 rg BT 545.80 209.10 Td (them ) Tj ET Q q 0 0 0 rg BT 568.22 209.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (market ) Tj ET Q q 0 0 0 rg BT 66.26 197.10 Td (in ) Tj ET Q q 0 0 0 rg BT 76.54 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 91.26 197.10 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 173.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.97 173.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 73.42 173.10 Td ( ) Tj ET Q q 0 0 0 rg BT 75.85 173.10 Td (mandates ) Tj ET Q q 0 0 0 rg BT 116.04 173.10 Td (that ) Tj ET Q q 0 0 0 rg BT 133.46 173.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 158.10 173.10 Td (be ) Tj ET Q q 0 0 0 rg BT 169.96 173.10 Td (manufactured, ) Tj ET Q q 0 0 0 rg BT 229.86 173.10 Td (packaged ) Tj ET Q q 0 0 0 rg BT 270.04 173.10 Td (and ) Tj ET Q q 0 0 0 rg BT 286.90 173.10 Td (labeled ) Tj ET Q q 0 0 0 rg BT 318.20 173.10 Td (in ) Tj ET Q q 0 0 0 rg BT 328.40 173.10 Td (conformity ) Tj ET Q q 0 0 0 rg BT 375.26 173.10 Td (with ) Tj ET Q q 0 0 0 rg BT 395.46 173.10 Td (cGMP) Tj ET Q q 0 0 0 rg BT 421.20 173.10 Td ( ) Tj ET Q q 0 0 0 rg BT 423.63 173.10 Td (established ) Tj ET Q q 0 0 0 rg BT 470.48 173.10 Td (by ) Tj ET Q q 0 0 0 rg BT 482.91 173.10 Td (the ) Tj ET Q q 0 0 0 rg BT 497.55 173.10 Td (FDA. ) Tj ET Q q 0 0 0 rg BT 522.48 173.10 Td (In ) Tj ET Q q 0 0 0 rg BT 533.23 173.10 Td (complying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (with ) Tj ET Q q 0 0 0 rg BT 55.93 161.10 Td (cGMP) Tj ET Q q 0 0 0 rg BT 81.67 161.10 Td ( ) Tj ET Q q 0 0 0 rg BT 83.82 161.10 Td (regulations, ) Tj ET Q q 0 0 0 rg BT 132.90 161.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 192.24 161.10 Td (must ) Tj ET Q q 0 0 0 rg BT 213.84 161.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 250.42 161.10 Td (to ) Tj ET Q q 0 0 0 rg BT 260.35 161.10 Td (expend ) Tj ET Q q 0 0 0 rg BT 291.37 161.10 Td (time, ) Tj ET Q q 0 0 0 rg BT 313.79 161.10 Td (money ) Tj ET Q q 0 0 0 rg BT 343.16 161.10 Td (and ) Tj ET Q q 0 0 0 rg BT 359.75 161.10 Td (ef) Tj ET Q q 0 0 0 rg BT 367.33 161.10 Td (fort ) Tj ET Q q 0 0 0 rg BT 383.92 161.10 Td (in ) Tj ET Q q 0 0 0 rg BT 393.85 161.10 Td (production, ) Tj ET Q q 0 0 0 rg BT 441.82 161.10 Td (recordkeeping ) Tj ET Q q 0 0 0 rg BT 501.16 161.10 Td (and ) Tj ET Q q 0 0 0 rg BT 517.75 161.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 547.67 161.10 Td (control ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 45.71 149.10 Td (ensure ) Tj ET Q q 0 0 0 rg BT 73.74 149.10 Td (that ) Tj ET Q q 0 0 0 rg BT 90.67 149.10 Td (products ) Tj ET Q q 0 0 0 rg BT 127.04 149.10 Td (meet ) Tj ET Q q 0 0 0 rg BT 148.41 149.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 191.43 149.10 Td (specifications ) Tj ET Q q 0 0 0 rg BT 248.34 149.10 Td (and ) Tj ET Q q 0 0 0 rg BT 264.71 149.10 Td (other ) Tj ET Q q 0 0 0 rg BT 287.19 149.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 341.33 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 351.04 149.10 Td (ensure ) Tj ET Q q 0 0 0 rg BT 379.07 149.10 Td (product ) Tj ET Q q 0 0 0 rg BT 411.55 149.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 437.36 149.10 Td (and ) Tj ET Q q 0 0 0 rg BT 453.73 149.10 Td (ef) Tj ET Q q 0 0 0 rg BT 461.32 149.10 Td (ficacy) Tj ET Q q 0 0 0 rg BT 485.09 149.10 Td (. ) Tj ET Q q 0 0 0 rg BT 489.38 149.10 Td (The ) Tj ET Q q 0 0 0 rg BT 506.86 149.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 526.32 149.10 Td ( ) Tj ET Q q 0 0 0 rg BT 528.25 149.10 Td (periodically ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.10 Td (inspects ) Tj ET Q q 0 0 0 rg BT 70.16 137.10 Td (our ) Tj ET Q q 0 0 0 rg BT 85.43 137.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 105.70 137.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 165.96 137.10 Td (facilities ) Tj ET Q q 0 0 0 rg BT 202.33 137.10 Td (to ) Tj ET Q q 0 0 0 rg BT 212.05 137.10 Td (ensure ) Tj ET Q q 0 0 0 rg BT 240.09 137.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 288.12 137.10 Td (with ) Tj ET Q q 0 0 0 rg BT 307.84 137.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 350.87 137.10 Td (cGMP) Tj ET Q q 0 0 0 rg BT 376.62 137.10 Td ( ) Tj ET Q q 0 0 0 rg BT 378.56 137.10 Td (requirements. ) Tj ET Q q 0 0 0 rg BT 435.20 137.10 Td (Failure ) Tj ET Q q 0 0 0 rg BT 465.47 137.10 Td (to ) Tj ET Q q 0 0 0 rg BT 475.19 137.10 Td (comply ) Tj ET Q q 0 0 0 rg BT 507.13 137.10 Td (with ) Tj ET Q q 0 0 0 rg BT 526.85 137.10 Td (the ) Tj ET Q q 0 0 0 rg BT 541.01 137.10 Td (statutory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.10 125.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 96.86 125.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 151.72 125.10 Td (subjects ) Tj ET Q q 0 0 0 rg BT 186.60 125.10 Td (us ) Tj ET Q q 0 0 0 rg BT 198.16 125.10 Td (to ) Tj ET Q q 0 0 0 rg BT 208.60 125.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 244.04 125.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 266.13 125.10 Td (or ) Tj ET Q q 0 0 0 rg BT 277.13 125.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 320.88 125.10 Td (action, ) Tj ET Q q 0 0 0 rg BT 350.48 125.10 Td (such ) Tj ET Q q 0 0 0 rg BT 371.47 125.10 Td (as ) Tj ET Q q 0 0 0 rg BT 382.46 125.10 Td (suspension ) Tj ET Q q 0 0 0 rg BT 429.02 125.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.01 125.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 503.48 125.10 Td (seizure ) Tj ET Q q 0 0 0 rg BT 534.46 125.10 Td (of ) Tj ET Q q 0 0 0 rg BT 545.46 125.10 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.10 Td (or ) Tj ET Q q 0 0 0 rg BT 47.76 113.10 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 89.52 113.10 Td (recall ) Tj ET Q q 0 0 0 rg BT 115.16 113.10 Td (of ) Tj ET Q q 0 0 0 rg BT 126.92 113.10 Td (a ) Tj ET Q q 0 0 0 rg BT 134.80 113.10 Td (product. ) Tj ET Q q 0 0 0 rg BT 170.52 113.10 Td (Adverse ) Tj ET Q q 0 0 0 rg BT 207.27 113.10 Td (experiences ) Tj ET Q q 0 0 0 rg BT 257.90 113.10 Td (with ) Tj ET Q q 0 0 0 rg BT 279.11 113.10 Td (the ) Tj ET Q q 0 0 0 rg BT 294.76 113.10 Td (use ) Tj ET Q q 0 0 0 rg BT 311.53 113.10 Td (of ) Tj ET Q q 0 0 0 rg BT 323.29 113.10 Td (products ) Tj ET Q q 0 0 0 rg BT 361.16 113.10 Td (must ) Tj ET Q q 0 0 0 rg BT 384.05 113.10 Td (be ) Tj ET Q q 0 0 0 rg BT 396.92 113.10 Td (reported ) Tj ET Q q 0 0 0 rg BT 433.67 113.10 Td (to ) Tj ET Q q 0 0 0 rg BT 444.88 113.10 Td (the ) Tj ET Q q 0 0 0 rg BT 460.53 113.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 479.98 113.10 Td ( ) Tj ET Q q 0 0 0 rg BT 483.42 113.10 Td (and ) Tj ET Q q 0 0 0 rg BT 501.29 113.10 Td (could ) Tj ET Q q 0 0 0 rg BT 526.94 113.10 Td (result ) Tj ET Q q 0 0 0 rg BT 552.59 113.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.81 113.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.10 Td (imposition ) Tj ET Q q 0 0 0 rg BT 81.00 101.10 Td (of ) Tj ET Q q 0 0 0 rg BT 91.54 101.10 Td (market ) Tj ET Q q 0 0 0 rg BT 121.52 101.10 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 168.17 101.10 Td (through ) Tj ET Q q 0 0 0 rg BT 201.49 101.10 Td (labeling ) Tj ET Q q 0 0 0 rg BT 235.92 101.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 270.34 101.10 Td (or ) Tj ET Q q 0 0 0 rg BT 280.88 101.10 Td (product ) Tj ET Q q 0 0 0 rg BT 313.64 101.10 Td (removal. ) Tj ET Q q 0 0 0 rg BT 351.12 101.10 Td (Product ) Tj ET Q q 0 0 0 rg BT 384.44 101.10 Td (approvals ) Tj ET Q q 0 0 0 rg BT 425.54 101.10 Td (may ) Tj ET Q q 0 0 0 rg BT 444.97 101.10 Td (be ) Tj ET Q q 0 0 0 rg BT 456.62 101.10 Td (withdrawn ) Tj ET Q q 0 0 0 rg BT 501.60 101.10 Td (if ) Tj ET Q q 0 0 0 rg BT 509.93 101.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 558.23 101.10 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 89.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 79.59 89.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 134.30 89.10 Td (is ) Tj ET Q q 0 0 0 rg BT 143.47 89.10 Td (not ) Tj ET Q q 0 0 0 rg BT 158.74 89.10 Td (maintained ) Tj ET Q q 0 0 0 rg BT 205.67 89.10 Td (or ) Tj ET Q q 0 0 0 rg BT 216.50 89.10 Td (if ) Tj ET Q q 0 0 0 rg BT 225.11 89.10 Td (problems ) Tj ET Q q 0 0 0 rg BT 264.83 89.10 Td (concerning ) Tj ET Q q 0 0 0 rg BT 311.75 89.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 338.13 89.10 Td (or ) Tj ET Q q 0 0 0 rg BT 348.96 89.10 Td (ef) Tj ET Q q 0 0 0 rg BT 356.55 89.10 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 383.47 89.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 408.18 89.10 Td (following ) Tj ET Q q 0 0 0 rg BT 449.56 89.10 Td (approval.) Tj ET Q endstream endobj 31 0 obj <> endobj 32 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.21 749.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 86.86 749.10 Td (government ) Tj ET Q q 0 0 0 rg BT 137.28 749.10 Td (has ) Tj ET Q q 0 0 0 rg BT 153.28 749.10 Td (extensive ) Tj ET Q q 0 0 0 rg BT 193.70 749.10 Td (enforcement ) Tj ET Q q 0 0 0 rg BT 246.34 749.10 Td (powers ) Tj ET Q q 0 0 0 rg BT 277.88 749.10 Td (over ) Tj ET Q q 0 0 0 rg BT 298.31 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 313.19 749.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 351.95 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 362.94 749.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 426.68 749.10 Td (manufacturers, ) Tj ET Q q 0 0 0 rg BT 489.04 749.10 Td (including ) Tj ET Q q 0 0 0 rg BT 529.47 749.10 Td (authority ) Tj ET Q q 0 0 0 rg BT 568.24 749.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (withdraw ) Tj ET Q q 0 0 0 rg BT 76.00 737.10 Td (or ) Tj ET Q q 0 0 0 rg BT 86.56 737.10 Td (delay ) Tj ET Q q 0 0 0 rg BT 110.45 737.10 Td (product ) Tj ET Q q 0 0 0 rg BT 143.22 737.10 Td (approvals, ) Tj ET Q q 0 0 0 rg BT 186.83 737.10 Td (commence ) Tj ET Q q 0 0 0 rg BT 232.37 737.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 262.93 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 272.94 737.10 Td (seize ) Tj ET Q q 0 0 0 rg BT 295.15 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 311.82 737.10 Td (prohibit ) Tj ET Q q 0 0 0 rg BT 345.72 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 360.16 737.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 377.94 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 388.50 737.10 Td (unapproved ) Tj ET Q q 0 0 0 rg BT 437.94 737.10 Td (or ) Tj ET Q q 0 0 0 rg BT 448.50 737.10 Td (non-complying ) Tj ET Q q 0 0 0 rg BT 511.83 737.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 551.00 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 561.01 737.10 Td (halt ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 96.91 725.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 141.17 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 158.76 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 173.57 725.10 Td (not ) Tj ET Q q 0 0 0 rg BT 188.95 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 199.33 725.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 248.01 725.10 Td (with ) Tj ET Q q 0 0 0 rg BT 268.39 725.10 Td (cGMPs, ) Tj ET Q q 0 0 0 rg BT 303.50 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 320.54 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 330.91 725.10 Td (impose ) Tj ET Q q 0 0 0 rg BT 362.40 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 373.33 725.10 Td (seek ) Tj ET Q q 0 0 0 rg BT 393.70 725.10 Td (injunctions, ) Tj ET Q q 0 0 0 rg BT 443.24 725.10 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 484.17 725.10 Td (recalls, ) Tj ET Q q 0 0 0 rg BT 515.36 725.10 Td (civil, ) Tj ET Q q 0 0 0 rg BT 538.24 725.10 Td (monetary ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.88 713.10 Td (criminal ) Tj ET Q q 0 0 0 rg BT 88.63 713.10 Td (penalties. ) Tj ET Q q 0 0 0 rg BT 129.11 713.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 151.55 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 158.43 713.10 Td (restriction ) Tj ET Q q 0 0 0 rg BT 201.41 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 212.18 713.10 Td (prohibition ) Tj ET Q q 0 0 0 rg BT 259.06 713.10 Td (on ) Tj ET Q q 0 0 0 rg BT 271.50 713.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 293.37 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 304.14 713.10 Td (withdrawal ) Tj ET Q q 0 0 0 rg BT 351.56 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 362.33 713.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 399.76 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 410.52 713.10 Td (products ) Tj ET Q q 0 0 0 rg BT 447.40 713.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 487.04 713.10 Td (by ) Tj ET Q q 0 0 0 rg BT 499.48 713.10 Td (us ) Tj ET Q q 0 0 0 rg BT 510.81 713.10 Td (could ) Tj ET Q q 0 0 0 rg BT 535.46 713.10 Td (materially ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (adversely ) Tj ET Q q 0 0 0 rg BT 76.82 701.10 Td (af) Tj ET Q q 0 0 0 rg BT 84.40 701.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 101.89 701.10 Td (our ) Tj ET Q q 0 0 0 rg BT 117.72 701.10 Td (business, ) Tj ET Q q 0 0 0 rg BT 156.61 701.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 194.09 701.10 Td (condition ) Tj ET Q q 0 0 0 rg BT 234.36 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 251.30 701.10 Td (results ) Tj ET Q q 0 0 0 rg BT 279.91 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 290.74 701.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 334.90 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 351.83 701.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 372.10 701.10 Td (flows.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (Marketing ) Tj ET Q q 0 0 0 rg BT 79.95 677.10 Td (authorization ) Tj ET Q q 0 0 0 rg BT 135.01 677.10 Td (for ) Tj ET Q q 0 0 0 rg BT 148.97 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 164.59 677.10 Td (products ) Tj ET Q q 0 0 0 rg BT 201.33 677.10 Td (is ) Tj ET Q q 0 0 0 rg BT 210.30 677.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 240.92 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 251.00 677.10 Td (revocation ) Tj ET Q q 0 0 0 rg BT 295.49 677.10 Td (by ) Tj ET Q q 0 0 0 rg BT 307.79 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 322.31 677.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 365.69 677.10 Td (governmental ) Tj ET Q q 0 0 0 rg BT 422.97 677.10 Td (agencies. ) Tj ET Q q 0 0 0 rg BT 462.19 677.10 Td (In ) Tj ET Q q 0 0 0 rg BT 472.82 677.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 510.39 677.10 Td (modifications ) Tj ET Q q 0 0 0 rg BT 567.68 677.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (enhancements ) Tj ET Q q 0 0 0 rg BT 94.11 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 103.90 665.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 142.57 665.10 Td (products ) Tj ET Q q 0 0 0 rg BT 178.48 665.10 Td (or ) Tj ET Q q 0 0 0 rg BT 188.27 665.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 221.94 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 231.19 665.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 290.96 665.10 Td (locations ) Tj ET Q q 0 0 0 rg BT 328.53 665.10 Td (are ) Tj ET Q q 0 0 0 rg BT 342.20 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 351.44 665.10 Td (many ) Tj ET Q q 0 0 0 rg BT 375.13 665.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 433.23 665.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 463.02 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 472.26 665.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 513.72 665.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 533.17 665.10 Td ( ) Tj ET Q q 0 0 0 rg BT 534.64 665.10 Td (approvals, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (which ) Tj ET Q q 0 0 0 rg BT 62.94 653.10 Td (may ) Tj ET Q q 0 0 0 rg BT 82.66 653.10 Td (or ) Tj ET Q q 0 0 0 rg BT 93.49 653.10 Td (may ) Tj ET Q q 0 0 0 rg BT 113.20 653.10 Td (not ) Tj ET Q q 0 0 0 rg BT 128.48 653.10 Td (be ) Tj ET Q q 0 0 0 rg BT 140.42 653.10 Td (received ) Tj ET Q q 0 0 0 rg BT 176.78 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 193.72 653.10 Td (may ) Tj ET Q q 0 0 0 rg BT 213.44 653.10 Td (be ) Tj ET Q q 0 0 0 rg BT 225.38 653.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 256.20 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 266.48 653.10 Td (a ) Tj ET Q q 0 0 0 rg BT 273.42 653.10 Td (lengthy ) Tj ET Q q 0 0 0 rg BT 305.91 653.10 Td (application ) Tj ET Q q 0 0 0 rg BT 352.84 653.10 Td (process.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.52 629.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 101.60 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 111.91 629.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 174.95 629.10 Td (products ) Tj ET Q q 0 0 0 rg BT 211.36 629.10 Td (is ) Tj ET Q q 0 0 0 rg BT 220.00 629.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 250.30 629.10 Td (to ) Tj ET Q q 0 0 0 rg BT 260.05 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 274.24 629.10 Td (PDMA) Tj ET Q q 0 0 0 rg BT 302.58 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 304.55 629.10 Td (as ) Tj ET Q q 0 0 0 rg BT 314.86 629.10 Td (part ) Tj ET Q q 0 0 0 rg BT 332.38 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 342.68 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 356.87 629.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 388.82 629.10 Td (Food, ) Tj ET Q q 0 0 0 rg BT 413.86 629.10 Td (Drug, ) Tj ET Q q 0 0 0 rg BT 438.88 629.10 Td (and ) Tj ET Q q 0 0 0 rg BT 455.29 629.10 Td (Cosmetic ) Tj ET Q q 0 0 0 rg BT 494.60 629.10 Td (Act, ) Tj ET Q q 0 0 0 rg BT 513.51 629.10 Td (which ) Tj ET Q q 0 0 0 rg BT 539.92 629.10 Td (regulates ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (such ) Tj ET Q q 0 0 0 rg BT 57.48 617.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 96.72 617.10 Td (at ) Tj ET Q q 0 0 0 rg BT 107.08 617.10 Td (both ) Tj ET Q q 0 0 0 rg BT 128.01 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 143.37 617.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 176.50 617.10 Td (and ) Tj ET Q q 0 0 0 rg BT 194.09 617.10 Td (state ) Tj ET Q q 0 0 0 rg BT 215.56 617.10 Td (level. ) Tj ET Q q 0 0 0 rg BT 240.64 617.10 Td (Under ) Tj ET Q q 0 0 0 rg BT 268.77 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 284.14 617.10 Td (PDMA) Tj ET Q q 0 0 0 rg BT 312.48 617.10 Td ( ) Tj ET Q q 0 0 0 rg BT 315.63 617.10 Td (and ) Tj ET Q q 0 0 0 rg BT 333.21 617.10 Td (its ) Tj ET Q q 0 0 0 rg BT 345.81 617.10 Td (implementing ) Tj ET Q q 0 0 0 rg BT 404.50 617.10 Td (regulations, ) Tj ET Q q 0 0 0 rg BT 454.58 617.10 Td (states ) Tj ET Q q 0 0 0 rg BT 479.94 617.10 Td (are ) Tj ET Q q 0 0 0 rg BT 495.29 617.10 Td (permitted ) Tj ET Q q 0 0 0 rg BT 536.76 617.10 Td (to ) Tj ET Q q 0 0 0 rg BT 547.68 617.10 Td (require ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (registration ) Tj ET Q q 0 0 0 rg BT 84.10 605.10 Td (of ) Tj ET Q q 0 0 0 rg BT 94.99 605.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 154.74 605.10 Td (and ) Tj ET Q q 0 0 0 rg BT 171.74 605.10 Td (distributors ) Tj ET Q q 0 0 0 rg BT 219.86 605.10 Td (who ) Tj ET Q q 0 0 0 rg BT 239.64 605.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 272.75 605.10 Td (pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 340.27 605.10 Td (even ) Tj ET Q q 0 0 0 rg BT 361.71 605.10 Td (if ) Tj ET Q q 0 0 0 rg BT 370.38 605.10 Td (such ) Tj ET Q q 0 0 0 rg BT 391.27 605.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 451.02 605.10 Td (or ) Tj ET Q q 0 0 0 rg BT 461.91 605.10 Td (distributors ) Tj ET Q q 0 0 0 rg BT 510.03 605.10 Td (have ) Tj ET Q q 0 0 0 rg BT 531.47 605.10 Td (no ) Tj ET Q q 0 0 0 rg BT 544.03 605.10 Td (place ) Tj ET Q q 0 0 0 rg BT 567.68 605.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (business ) Tj ET Q q 0 0 0 rg BT 71.39 593.10 Td (within ) Tj ET Q q 0 0 0 rg BT 98.44 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 112.16 593.10 Td (state. ) Tj ET Q q 0 0 0 rg BT 134.48 593.10 Td (States ) Tj ET Q q 0 0 0 rg BT 159.87 593.10 Td (are ) Tj ET Q q 0 0 0 rg BT 173.57 593.10 Td (also ) Tj ET Q q 0 0 0 rg BT 191.18 593.10 Td (permitted ) Tj ET Q q 0 0 0 rg BT 231.00 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 240.27 593.10 Td (adopt ) Tj ET Q q 0 0 0 rg BT 263.99 593.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 309.92 593.10 Td (limiting ) Tj ET Q q 0 0 0 rg BT 343.09 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 356.80 593.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 404.41 593.10 Td (of ) Tj ET Q q 0 0 0 rg BT 414.24 593.10 Td (product ) Tj ET Q q 0 0 0 rg BT 446.29 593.10 Td (samples ) Tj ET Q q 0 0 0 rg BT 480.00 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 489.28 593.10 Td (licensed ) Tj ET Q q 0 0 0 rg BT 523.54 593.10 Td (practitioners. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.03 581.10 Td (PDMA) Tj ET Q q 0 0 0 rg BT 81.37 581.10 Td ( ) Tj ET Q q 0 0 0 rg BT 82.85 581.10 Td (also ) Tj ET Q q 0 0 0 rg BT 100.44 581.10 Td (imposes ) Tj ET Q q 0 0 0 rg BT 134.69 581.10 Td (extensive ) Tj ET Q q 0 0 0 rg BT 173.93 581.10 Td (licensing, ) Tj ET Q q 0 0 0 rg BT 214.02 581.10 Td (personnel ) Tj ET Q q 0 0 0 rg BT 254.37 581.10 Td (recordkeeping, ) Tj ET Q q 0 0 0 rg BT 315.54 581.10 Td (packaging, ) Tj ET Q q 0 0 0 rg BT 360.62 581.10 Td (quantity) Tj ET Q q 0 0 0 rg BT 392.74 581.10 Td (, ) Tj ET Q q 0 0 0 rg BT 396.72 581.10 Td (labeling, ) Tj ET Q q 0 0 0 rg BT 432.91 581.10 Td (product ) Tj ET Q q 0 0 0 rg BT 464.93 581.10 Td (handling ) Tj ET Q q 0 0 0 rg BT 501.41 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 517.32 581.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 547.12 581.10 Td (storage ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 569.10 Td (security ) Tj ET Q q 0 0 0 rg BT 87.09 569.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 141.80 569.10 Td (intended ) Tj ET Q q 0 0 0 rg BT 178.73 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 189.01 569.10 Td (prevent ) Tj ET Q q 0 0 0 rg BT 221.49 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 236.21 569.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 254.26 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 265.09 569.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 328.66 569.10 Td (product ) Tj ET Q q 0 0 0 rg BT 361.71 569.10 Td (samples ) Tj ET Q q 0 0 0 rg BT 396.42 569.10 Td (or ) Tj ET Q q 0 0 0 rg BT 407.25 569.10 Td (other ) Tj ET Q q 0 0 0 rg BT 430.30 569.10 Td (product ) Tj ET Q q 0 0 0 rg BT 463.35 569.10 Td (diversions.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (The ) Tj ET Q q 0 0 0 rg BT 55.22 545.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 74.67 545.10 Td ( ) Tj ET Q q 0 0 0 rg BT 77.54 545.10 Td (Amendments ) Tj ET Q q 0 0 0 rg BT 133.73 545.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 151.84 545.10 Td (of ) Tj ET Q q 0 0 0 rg BT 163.84 545.10 Td (2007 ) Tj ET Q q 0 0 0 rg BT 187.52 545.10 Td (imposed ) Tj ET Q q 0 0 0 rg BT 225.08 545.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 268.74 545.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 316.86 545.10 Td (on ) Tj ET Q q 0 0 0 rg BT 330.54 545.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 395.28 545.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 441.72 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 459.83 545.10 Td (delegated ) Tj ET Q q 0 0 0 rg BT 501.82 545.10 Td (more ) Tj ET Q q 0 0 0 rg BT 526.04 545.10 Td (enforcement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (authority ) Tj ET Q q 0 0 0 rg BT 75.09 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 85.86 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.07 533.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 120.52 533.10 Td ( ) Tj ET Q q 0 0 0 rg BT 123.51 533.10 Td (in ) Tj ET Q q 0 0 0 rg BT 134.28 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 149.49 533.10 Td (area ) Tj ET Q q 0 0 0 rg BT 169.13 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 180.45 533.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 201.77 533.10 Td (safety) Tj ET Q q 0 0 0 rg BT 225.00 533.10 Td (. ) Tj ET Q q 0 0 0 rg BT 230.49 533.10 Td (Key ) Tj ET Q q 0 0 0 rg BT 250.14 533.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 288.67 533.10 Td (of ) Tj ET Q q 0 0 0 rg BT 299.99 533.10 Td (this ) Tj ET Q q 0 0 0 rg BT 317.43 533.10 Td (legislation ) Tj ET Q q 0 0 0 rg BT 362.08 533.10 Td (give ) Tj ET Q q 0 0 0 rg BT 382.29 533.10 Td (the ) Tj ET Q q 0 0 0 rg BT 397.50 533.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 416.95 533.10 Td ( ) Tj ET Q q 0 0 0 rg BT 419.94 533.10 Td (authority ) Tj ET Q q 0 0 0 rg BT 459.03 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 469.80 533.10 Td (\(1\) require ) Tj ET Q q 0 0 0 rg BT 515.27 533.10 Td (that ) Tj ET Q q 0 0 0 rg BT 533.26 533.10 Td (companies ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (conduct ) Tj ET Q q 0 0 0 rg BT 71.15 521.10 Td (post-marketing ) Tj ET Q q 0 0 0 rg BT 135.18 521.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 162.55 521.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 193.82 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 205.65 521.10 Td (drugs, ) Tj ET Q q 0 0 0 rg BT 233.86 521.10 Td (\(2\) impose ) Tj ET Q q 0 0 0 rg BT 280.40 521.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 311.09 521.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 338.46 521.10 Td (related ) Tj ET Q q 0 0 0 rg BT 369.16 521.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 390.98 521.10 Td (labeling ) Tj ET Q q 0 0 0 rg BT 426.69 521.10 Td (changes, ) Tj ET Q q 0 0 0 rg BT 464.89 521.10 Td (\(3\) mandate ) Tj ET Q q 0 0 0 rg BT 516.41 521.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 534.90 521.10 Td (mitigation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (measures ) Tj ET Q q 0 0 0 rg BT 76.19 509.10 Td (such ) Tj ET Q q 0 0 0 rg BT 97.51 509.10 Td (as ) Tj ET Q q 0 0 0 rg BT 108.82 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 124.02 509.10 Td (education ) Tj ET Q q 0 0 0 rg BT 165.88 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 177.20 509.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 221.26 509.10 Td (providers ) Tj ET Q q 0 0 0 rg BT 262.01 509.10 Td (and ) Tj ET Q q 0 0 0 rg BT 279.44 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 294.64 509.10 Td (restricted ) Tj ET Q q 0 0 0 rg BT 334.82 509.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 383.92 509.10 Td (of ) Tj ET Q q 0 0 0 rg BT 395.24 509.10 Td (medicines, ) Tj ET Q q 0 0 0 rg BT 441.26 509.10 Td (\(4\) require ) Tj ET Q q 0 0 0 rg BT 486.73 509.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 532.47 509.10 Td (to ) Tj ET Q q 0 0 0 rg BT 543.24 509.10 Td (publicly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (disclose ) Tj ET Q q 0 0 0 rg BT 70.72 497.10 Td (data ) Tj ET Q q 0 0 0 rg BT 89.87 497.10 Td (from ) Tj ET Q q 0 0 0 rg BT 111.81 497.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 143.74 497.10 Td (studies ) Tj ET Q q 0 0 0 rg BT 174.02 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 190.96 497.10 Td (\(5\) pre-review ) Tj ET Q q 0 0 0 rg BT 250.92 497.10 Td (television ) Tj ET Q q 0 0 0 rg BT 292.30 497.10 Td (advertisements.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.67 473.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 96.33 473.10 Td (practices ) Tj ET Q q 0 0 0 rg BT 133.99 473.10 Td (of ) Tj ET Q q 0 0 0 rg BT 144.44 473.10 Td (all ) Tj ET Q q 0 0 0 rg BT 156.56 473.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 176.47 473.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 239.67 473.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 298.98 473.10 Td (are ) Tj ET Q q 0 0 0 rg BT 313.31 473.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 343.76 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 353.66 473.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 385.77 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 402.33 473.10 Td (state ) Tj ET Q q 0 0 0 rg BT 422.78 473.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 465.98 473.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 486.43 473.10 Td (that ) Tj ET Q q 0 0 0 rg BT 503.55 473.10 Td (are ) Tj ET Q q 0 0 0 rg BT 517.88 473.10 Td (used ) Tj ET Q q 0 0 0 rg BT 538.33 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 548.24 473.10 Td (protect ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.25 461.10 Td (integrity ) Tj ET Q q 0 0 0 rg BT 88.16 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 99.52 461.10 Td (government ) Tj ET Q q 0 0 0 rg BT 150.32 461.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 194.43 461.10 Td (programs. ) Tj ET Q q 0 0 0 rg BT 237.51 461.10 Td (The ) Tj ET Q q 0 0 0 rg BT 256.09 461.10 Td (OIG ) Tj ET Q q 0 0 0 rg BT 276.89 461.10 Td (oversees ) Tj ET Q q 0 0 0 rg BT 314.35 461.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 363.47 461.10 Td (with ) Tj ET Q q 0 0 0 rg BT 384.28 461.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 428.40 461.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 461.42 461.10 Td (laws, ) Tj ET Q q 0 0 0 rg BT 485.28 461.10 Td (in ) Tj ET Q q 0 0 0 rg BT 496.09 461.10 Td (connection ) Tj ET Q q 0 0 0 rg BT 542.99 461.10 Td (with ) Tj ET Q q 0 0 0 rg BT 563.80 461.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 72.68 449.10 Td (for ) Tj ET Q q 0 0 0 rg BT 86.58 449.10 Td (products ) Tj ET Q q 0 0 0 rg BT 123.26 449.10 Td (by ) Tj ET Q q 0 0 0 rg BT 135.51 449.10 Td (government ) Tj ET Q q 0 0 0 rg BT 185.51 449.10 Td (funded ) Tj ET Q q 0 0 0 rg BT 215.53 449.10 Td (programs, ) Tj ET Q q 0 0 0 rg BT 258.04 449.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 297.49 449.10 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 337.50 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 354.18 449.10 Td (Medicare. ) Tj ET Q q 0 0 0 rg BT 396.52 449.10 Td (These ) Tj ET Q q 0 0 0 rg BT 422.64 449.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 443.21 449.10 Td (include ) Tj ET Q q 0 0 0 rg BT 474.89 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 489.35 449.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 521.58 449.10 Td (anti-kickback ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (statute, ) Tj ET Q q 0 0 0 rg BT 67.20 437.10 Td (which ) Tj ET Q q 0 0 0 rg BT 94.23 437.10 Td (criminalizes ) Tj ET Q q 0 0 0 rg BT 145.69 437.10 Td (the ) Tj ET Q q 0 0 0 rg BT 160.50 437.10 Td (of) Tj ET Q q 0 0 0 rg BT 168.65 437.10 Td (fering ) Tj ET Q q 0 0 0 rg BT 195.12 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 206.04 437.10 Td (something ) Tj ET Q q 0 0 0 rg BT 250.30 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 261.22 437.10 Td (value ) Tj ET Q q 0 0 0 rg BT 285.47 437.10 Td (to ) Tj ET Q q 0 0 0 rg BT 295.84 437.10 Td (induce ) Tj ET Q q 0 0 0 rg BT 325.09 437.10 Td (the ) Tj ET Q q 0 0 0 rg BT 339.90 437.10 Td (recommendation, ) Tj ET Q q 0 0 0 rg BT 412.19 437.10 Td (order ) Tj ET Q q 0 0 0 rg BT 435.88 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 446.80 437.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 484.93 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 495.85 437.10 Td (products ) Tj ET Q q 0 0 0 rg BT 532.88 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 543.81 437.10 Td (services ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (reimbursed ) Tj ET Q q 0 0 0 rg BT 83.85 425.10 Td (under ) Tj ET Q q 0 0 0 rg BT 109.48 425.10 Td (a ) Tj ET Q q 0 0 0 rg BT 116.78 425.10 Td (government ) Tj ET Q q 0 0 0 rg BT 167.41 425.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 211.35 425.10 Td (program. ) Tj ET Q q 0 0 0 rg BT 250.38 425.10 Td (The ) Tj ET Q q 0 0 0 rg BT 268.79 425.10 Td (OIG ) Tj ET Q q 0 0 0 rg BT 289.43 425.10 Td (has ) Tj ET Q q 0 0 0 rg BT 305.62 425.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 333.48 425.10 Td (a ) Tj ET Q q 0 0 0 rg BT 340.78 425.10 Td (series ) Tj ET Q q 0 0 0 rg BT 366.42 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 377.61 425.10 Td (guidances ) Tj ET Q q 0 0 0 rg BT 420.46 425.10 Td (to ) Tj ET Q q 0 0 0 rg BT 431.10 425.10 Td (segments ) Tj ET Q q 0 0 0 rg BT 471.18 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 482.37 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 497.45 425.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 541.39 425.10 Td (industry) Tj ET Q q 0 0 0 rg BT 573.52 425.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (including ) Tj ET Q q 0 0 0 rg BT 79.19 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 96.83 413.10 Td (2003 ) Tj ET Q q 0 0 0 rg BT 122.25 413.10 Td (Compliance ) Tj ET Q q 0 0 0 rg BT 175.98 413.10 Td (Program ) Tj ET Q q 0 0 0 rg BT 215.84 413.10 Td (Guidance ) Tj ET Q q 0 0 0 rg BT 259.58 413.10 Td (for ) Tj ET Q q 0 0 0 rg BT 276.65 413.10 Td (Pharmaceutical ) Tj ET Q q 0 0 0 rg BT 343.71 413.10 Td (Manufacturers, ) Tj ET Q q 0 0 0 rg BT 409.93 413.10 Td (which ) Tj ET Q q 0 0 0 rg BT 439.79 413.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 478.53 413.10 Td (a ) Tj ET Q q 0 0 0 rg BT 488.39 413.10 Td (recommendation ) Tj ET Q q 0 0 0 rg BT 561.01 413.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 98.80 401.10 Td (manufacturers, ) Tj ET Q q 0 0 0 rg BT 160.22 401.10 Td (at ) Tj ET Q q 0 0 0 rg BT 169.17 401.10 Td (a ) Tj ET Q q 0 0 0 rg BT 175.34 401.10 Td (minimum, ) Tj ET Q q 0 0 0 rg BT 218.46 401.10 Td (adhere ) Tj ET Q q 0 0 0 rg BT 246.83 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 256.34 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 270.28 401.10 Td (PhRMA) Tj ET Q q 0 0 0 rg BT 303.08 401.10 Td ( ) Tj ET Q q 0 0 0 rg BT 304.80 401.10 Td (Code, ) Tj ET Q q 0 0 0 rg BT 330.14 401.10 Td (a ) Tj ET Q q 0 0 0 rg BT 336.31 401.10 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 376.36 401.10 Td (industry ) Tj ET Q q 0 0 0 rg BT 410.87 401.10 Td (code ) Tj ET Q q 0 0 0 rg BT 431.47 401.10 Td (of ) Tj ET Q q 0 0 0 rg BT 441.53 401.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 483.80 401.10 Td (practices. ) Tj ET Q q 0 0 0 rg BT 523.44 401.10 Td (W) Tj ET Q q 0 0 0 rg BT 532.08 401.10 Td (e ) Tj ET Q q 0 0 0 rg BT 538.24 401.10 Td (subscribe ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (to ) Tj ET Q q 0 0 0 rg BT 45.25 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 58.95 389.10 Td (PhRMA) Tj ET Q q 0 0 0 rg BT 91.74 389.10 Td ( ) Tj ET Q q 0 0 0 rg BT 93.22 389.10 Td (Code, ) Tj ET Q q 0 0 0 rg BT 118.30 389.10 Td (and ) Tj ET Q q 0 0 0 rg BT 134.22 389.10 Td (have ) Tj ET Q q 0 0 0 rg BT 154.57 389.10 Td (implemented ) Tj ET Q q 0 0 0 rg BT 208.25 389.10 Td (a ) Tj ET Q q 0 0 0 rg BT 214.17 389.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 261.73 389.10 Td (program ) Tj ET Q q 0 0 0 rg BT 297.08 389.10 Td (to ) Tj ET Q q 0 0 0 rg BT 306.34 389.10 Td (address ) Tj ET Q q 0 0 0 rg BT 337.80 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 351.50 389.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 405.18 389.10 Td (set ) Tj ET Q q 0 0 0 rg BT 417.76 389.10 Td (forth ) Tj ET Q q 0 0 0 rg BT 438.67 389.10 Td (in ) Tj ET Q q 0 0 0 rg BT 447.93 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 461.62 389.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 499.19 389.10 Td (and ) Tj ET Q q 0 0 0 rg BT 515.11 389.10 Td (our ) Tj ET Q q 0 0 0 rg BT 529.91 389.10 Td (compliance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (with ) Tj ET Q q 0 0 0 rg BT 55.75 377.10 Td (the ) Tj ET Q q 0 0 0 rg BT 69.93 377.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 112.98 377.10 Td (laws. ) Tj ET Q q 0 0 0 rg BT 135.78 377.10 Td (Failure ) Tj ET Q q 0 0 0 rg BT 166.07 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 175.81 377.10 Td (comply ) Tj ET Q q 0 0 0 rg BT 207.78 377.10 Td (with ) Tj ET Q q 0 0 0 rg BT 227.52 377.10 Td (these ) Tj ET Q q 0 0 0 rg BT 250.04 377.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 293.08 377.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 313.38 377.10 Td (could ) Tj ET Q q 0 0 0 rg BT 337.57 377.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 367.86 377.10 Td (us ) Tj ET Q q 0 0 0 rg BT 378.72 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 388.47 377.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 447.64 377.10 Td (and ) Tj ET Q q 0 0 0 rg BT 464.05 377.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 485.45 377.10 Td (proceedings, ) Tj ET Q q 0 0 0 rg BT 538.23 377.10 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 66.50 365.10 Td (by ) Tj ET Q q 0 0 0 rg BT 78.67 365.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 110.83 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 127.45 365.10 Td (state ) Tj ET Q q 0 0 0 rg BT 147.95 365.10 Td (government ) Tj ET Q q 0 0 0 rg BT 197.88 365.10 Td (agencies. ) Tj ET Q q 0 0 0 rg BT 236.98 365.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 259.16 365.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 289.66 365.10 Td (could ) Tj ET Q q 0 0 0 rg BT 314.05 365.10 Td (result ) Tj ET Q q 0 0 0 rg BT 338.44 365.10 Td (in ) Tj ET Q q 0 0 0 rg BT 348.39 365.10 Td (the ) Tj ET Q q 0 0 0 rg BT 362.78 365.10 Td (imposition ) Tj ET Q q 0 0 0 rg BT 407.74 365.10 Td (of ) Tj ET Q q 0 0 0 rg BT 418.24 365.10 Td (civil ) Tj ET Q q 0 0 0 rg BT 438.19 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 454.80 365.10 Td (criminal ) Tj ET Q q 0 0 0 rg BT 490.30 365.10 Td (sanctions, ) Tj ET Q q 0 0 0 rg BT 532.19 365.10 Td (which ) Tj ET Q q 0 0 0 rg BT 558.80 365.10 Td (may ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (include ) Tj ET Q q 0 0 0 rg BT 67.87 353.10 Td (fines, ) Tj ET Q q 0 0 0 rg BT 92.25 353.10 Td (penalties ) Tj ET Q q 0 0 0 rg BT 130.24 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 147.11 353.10 Td (injunctive ) Tj ET Q q 0 0 0 rg BT 189.54 353.10 Td (remedies; ) Tj ET Q q 0 0 0 rg BT 230.86 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 245.51 353.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 275.17 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 285.94 353.10 Td (which ) Tj ET Q q 0 0 0 rg BT 312.82 353.10 Td (could ) Tj ET Q q 0 0 0 rg BT 337.47 353.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 380.45 353.10 Td (adversely ) Tj ET Q q 0 0 0 rg BT 421.21 353.10 Td (af) Tj ET Q q 0 0 0 rg BT 428.79 353.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 446.22 353.10 Td (our ) Tj ET Q q 0 0 0 rg BT 461.99 353.10 Td (business, ) Tj ET Q q 0 0 0 rg BT 500.82 353.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 538.24 353.10 Td (condition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 341.10 Td (results ) Tj ET Q q 0 0 0 rg BT 81.55 341.10 Td (of ) Tj ET Q q 0 0 0 rg BT 92.38 341.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 136.53 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 153.47 341.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 173.74 341.10 Td (flows.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 317.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.64 317.10 Td (are ) Tj ET Q q 0 0 0 rg BT 66.41 317.10 Td (also ) Tj ET Q q 0 0 0 rg BT 85.08 317.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 115.97 317.10 Td (to ) Tj ET Q q 0 0 0 rg BT 126.31 317.10 Td (the ) Tj ET Q q 0 0 0 rg BT 141.09 317.10 Td (jurisdiction ) Tj ET Q q 0 0 0 rg BT 189.21 317.10 Td (of ) Tj ET Q q 0 0 0 rg BT 200.10 317.10 Td (various ) Tj ET Q q 0 0 0 rg BT 232.10 317.10 Td (other ) Tj ET Q q 0 0 0 rg BT 255.21 317.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 287.76 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 304.76 317.10 Td (state ) Tj ET Q q 0 0 0 rg BT 325.65 317.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 369.31 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 386.31 317.10 Td (enforcement ) Tj ET Q q 0 0 0 rg BT 438.85 317.10 Td (departments ) Tj ET Q q 0 0 0 rg BT 490.28 317.10 Td (and ) Tj ET Q q 0 0 0 rg BT 507.28 317.10 Td (agencies, ) Tj ET Q q 0 0 0 rg BT 546.77 317.10 Td (such ) Tj ET Q q 0 0 0 rg BT 567.67 317.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.14 305.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 83.85 305.10 Td (T) Tj ET Q q 0 0 0 rg BT 89.60 305.10 Td (rade ) Tj ET Q q 0 0 0 rg BT 109.74 305.10 Td (Commission, ) Tj ET Q q 0 0 0 rg BT 165.73 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 180.87 305.10 Td (Department ) Tj ET Q q 0 0 0 rg BT 231.00 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 242.26 305.10 Td (Justice ) Tj ET Q q 0 0 0 rg BT 272.40 305.10 Td (and ) Tj ET Q q 0 0 0 rg BT 289.77 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 304.91 305.10 Td (Department ) Tj ET Q q 0 0 0 rg BT 355.04 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 366.30 305.10 Td (Health ) Tj ET Q q 0 0 0 rg BT 395.88 305.10 Td (and ) Tj ET Q q 0 0 0 rg BT 413.25 305.10 Td (Human ) Tj ET Q q 0 0 0 rg BT 445.62 305.10 Td (Services ) Tj ET Q q 0 0 0 rg BT 482.42 305.10 Td (in ) Tj ET Q q 0 0 0 rg BT 493.13 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 508.27 305.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 528.77 305.10 Td (W) Tj ET Q q 0 0 0 rg BT 537.41 305.10 Td (e ) Tj ET Q q 0 0 0 rg BT 544.77 305.10 Td (are ) Tj ET Q q 0 0 0 rg BT 559.91 305.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (licensed ) Tj ET Q q 0 0 0 rg BT 72.04 293.10 Td (by ) Tj ET Q q 0 0 0 rg BT 85.31 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.79 293.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 121.85 293.10 Td (Drug ) Tj ET Q q 0 0 0 rg BT 145.67 293.10 Td (Enforcement ) Tj ET Q q 0 0 0 rg BT 199.86 293.10 Td (Agency ) Tj ET Q q 0 0 0 rg BT 234.23 293.10 Td (to ) Tj ET Q q 0 0 0 rg BT 245.28 293.10 Td (procure ) Tj ET Q q 0 0 0 rg BT 279.09 293.10 Td (and ) Tj ET Q q 0 0 0 rg BT 296.80 293.10 Td (produce ) Tj ET Q q 0 0 0 rg BT 332.28 293.10 Td (controlled ) Tj ET Q q 0 0 0 rg BT 376.09 293.10 Td (substances. ) Tj ET Q q 0 0 0 rg BT 424.40 293.10 Td (W) Tj ET Q q 0 0 0 rg BT 433.03 293.10 Td (e ) Tj ET Q q 0 0 0 rg BT 440.74 293.10 Td (are, ) Tj ET Q q 0 0 0 rg BT 458.72 293.10 Td (therefore, ) Tj ET Q q 0 0 0 rg BT 500.58 293.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 532.18 293.10 Td (to ) Tj ET Q q 0 0 0 rg BT 543.23 293.10 Td (possible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 95.67 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 112.56 281.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 134.45 281.10 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 185.23 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 202.13 281.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 232.91 281.10 Td (by ) Tj ET Q q 0 0 0 rg BT 245.37 281.10 Td (these ) Tj ET Q q 0 0 0 rg BT 268.37 281.10 Td (or) Tj ET Q q 0 0 0 rg BT 276.52 281.10 Td (ganizations. ) Tj ET Q q 0 0 0 rg BT 327.02 281.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 349.48 281.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 380.27 281.10 Td (may ) Tj ET Q q 0 0 0 rg BT 399.94 281.10 Td (result ) Tj ET Q q 0 0 0 rg BT 424.62 281.10 Td (in ) Tj ET Q q 0 0 0 rg BT 434.85 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 449.53 281.10 Td (imposition ) Tj ET Q q 0 0 0 rg BT 494.77 281.10 Td (of ) Tj ET Q q 0 0 0 rg BT 505.56 281.10 Td (civil ) Tj ET Q q 0 0 0 rg BT 525.79 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 542.69 281.10 Td (criminal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (sanctions, ) Tj ET Q q 0 0 0 rg BT 78.22 269.10 Td (which ) Tj ET Q q 0 0 0 rg BT 105.16 269.10 Td (may ) Tj ET Q q 0 0 0 rg BT 124.87 269.10 Td (include ) Tj ET Q q 0 0 0 rg BT 156.81 269.10 Td (fines, ) Tj ET Q q 0 0 0 rg BT 181.24 269.10 Td (penalties ) Tj ET Q q 0 0 0 rg BT 219.29 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 236.22 269.10 Td (injunctive ) Tj ET Q q 0 0 0 rg BT 278.71 269.10 Td (or ) Tj ET Q q 0 0 0 rg BT 289.54 269.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 349.25 269.10 Td (remedies.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.62 245.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 73.48 245.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 116.64 245.10 Td (industry ) Tj ET Q q 0 0 0 rg BT 151.49 245.10 Td (is ) Tj ET Q q 0 0 0 rg BT 160.24 245.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 190.64 245.10 Td (to ) Tj ET Q q 0 0 0 rg BT 200.50 245.10 Td (various ) Tj ET Q q 0 0 0 rg BT 232.01 245.10 Td (government-imposed ) Tj ET Q q 0 0 0 rg BT 319.07 245.10 Td (regulations ) Tj ET Q q 0 0 0 rg BT 365.58 245.10 Td (authorizing ) Tj ET Q q 0 0 0 rg BT 413.20 245.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 439.15 245.10 Td (or ) Tj ET Q q 0 0 0 rg BT 449.56 245.10 Td (price ) Tj ET Q q 0 0 0 rg BT 471.62 245.10 Td (controls ) Tj ET Q q 0 0 0 rg BT 505.91 245.10 Td (that ) Tj ET Q q 0 0 0 rg BT 522.99 245.10 Td (have ) Tj ET Q q 0 0 0 rg BT 543.94 245.10 Td (and ) Tj ET Q q 0 0 0 rg BT 560.46 245.10 Td (will ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 72.02 233.10 Td (to ) Tj ET Q q 0 0 0 rg BT 81.39 233.10 Td (have ) Tj ET Q q 0 0 0 rg BT 101.85 233.10 Td (an ) Tj ET Q q 0 0 0 rg BT 112.88 233.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 141.68 233.10 Td (on ) Tj ET Q q 0 0 0 rg BT 153.27 233.10 Td (our ) Tj ET Q q 0 0 0 rg BT 168.19 233.10 Td (total ) Tj ET Q q 0 0 0 rg BT 187.55 233.10 Td (revenues. ) Tj ET Q q 0 0 0 rg BT 227.06 233.10 Td (W) Tj ET Q q 0 0 0 rg BT 235.70 233.10 Td (e ) Tj ET Q q 0 0 0 rg BT 241.72 233.10 Td (participate ) Tj ET Q q 0 0 0 rg BT 285.51 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 294.88 233.10 Td (state ) Tj ET Q q 0 0 0 rg BT 314.79 233.10 Td (government ) Tj ET Q q 0 0 0 rg BT 364.14 233.10 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 403.49 233.10 Td (programs, ) Tj ET Q q 0 0 0 rg BT 445.35 233.10 Td (as ) Tj ET Q q 0 0 0 rg BT 455.27 233.10 Td (well ) Tj ET Q q 0 0 0 rg BT 474.08 233.10 Td (as ) Tj ET Q q 0 0 0 rg BT 483.99 233.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 512.78 233.10 Td (other ) Tj ET Q q 0 0 0 rg BT 534.92 233.10 Td (qualifying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 68.30 221.10 Td (and ) Tj ET Q q 0 0 0 rg BT 85.05 221.10 Td (state ) Tj ET Q q 0 0 0 rg BT 105.69 221.10 Td (government ) Tj ET Q q 0 0 0 rg BT 155.77 221.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 195.85 221.10 Td (whereby ) Tj ET Q q 0 0 0 rg BT 232.60 221.10 Td (discounts ) Tj ET Q q 0 0 0 rg BT 272.69 221.10 Td (and ) Tj ET Q q 0 0 0 rg BT 289.44 221.10 Td (rebates ) Tj ET Q q 0 0 0 rg BT 320.07 221.10 Td (are ) Tj ET Q q 0 0 0 rg BT 334.59 221.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 372.46 221.10 Td (to ) Tj ET Q q 0 0 0 rg BT 382.55 221.10 Td (participating ) Tj ET Q q 0 0 0 rg BT 435.40 221.10 Td (state ) Tj ET Q q 0 0 0 rg BT 456.04 221.10 Td (and ) Tj ET Q q 0 0 0 rg BT 472.79 221.10 Td (local ) Tj ET Q q 0 0 0 rg BT 494.54 221.10 Td (government ) Tj ET Q q 0 0 0 rg BT 544.62 221.10 Td (entities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 209.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.61 209.10 Td (also ) Tj ET Q q 0 0 0 rg BT 70.26 209.10 Td (participate ) Tj ET Q q 0 0 0 rg BT 114.99 209.10 Td (in ) Tj ET Q q 0 0 0 rg BT 125.31 209.10 Td (government ) Tj ET Q q 0 0 0 rg BT 175.61 209.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 215.91 209.10 Td (that ) Tj ET Q q 0 0 0 rg BT 233.44 209.10 Td (specify ) Tj ET Q q 0 0 0 rg BT 264.86 209.10 Td (discounts ) Tj ET Q q 0 0 0 rg BT 305.17 209.10 Td (to ) Tj ET Q q 0 0 0 rg BT 315.49 209.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 345.23 209.10 Td (government ) Tj ET Q q 0 0 0 rg BT 395.53 209.10 Td (entities; ) Tj ET Q q 0 0 0 rg BT 429.72 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 444.48 209.10 Td (most ) Tj ET Q q 0 0 0 rg BT 466.46 209.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 511.21 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 522.08 209.10 Td (which ) Tj ET Q q 0 0 0 rg BT 549.05 209.10 Td (are ) Tj ET Q q 0 0 0 rg BT 563.80 209.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 56.03 197.10 Td (Department ) Tj ET Q q 0 0 0 rg BT 105.49 197.10 Td (of ) Tj ET Q q 0 0 0 rg BT 116.07 197.10 Td (Defense ) Tj ET Q q 0 0 0 rg BT 151.07 197.10 Td (and ) Tj ET Q q 0 0 0 rg BT 167.76 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 182.23 197.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 202.26 197.10 Td (Department ) Tj ET Q q 0 0 0 rg BT 251.71 197.10 Td (of ) Tj ET Q q 0 0 0 rg BT 262.13 197.10 Td (V) Tj ET Q q 0 0 0 rg BT 268.25 197.10 Td (eterans ) Tj ET Q q 0 0 0 rg BT 298.31 197.10 Td (Af) Tj ET Q q 0 0 0 rg BT 308.69 197.10 Td (fairs. ) Tj ET Q q 0 0 0 rg BT 331.04 197.10 Td (These ) Tj ET Q q 0 0 0 rg BT 357.17 197.10 Td (entities ) Tj ET Q q 0 0 0 rg BT 388.30 197.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 419.41 197.10 Td (minimum ) Tj ET Q q 0 0 0 rg BT 460.55 197.10 Td (discounts ) Tj ET Q q 0 0 0 rg BT 500.58 197.10 Td (based ) Tj ET Q q 0 0 0 rg BT 525.60 197.10 Td (of) Tj ET Q q 0 0 0 rg BT 533.75 197.10 Td (f ) Tj ET Q q 0 0 0 rg BT 539.33 197.10 Td (a ) Tj ET Q q 0 0 0 rg BT 546.02 197.10 Td (defined ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.10 Td (“non-federal ) Tj ET Q q 0 0 0 rg BT 88.66 185.10 Td (average ) Tj ET Q q 0 0 0 rg BT 121.87 185.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 177.31 185.10 Td (price” ) Tj ET Q q 0 0 0 rg BT 203.86 185.10 Td (for ) Tj ET Q q 0 0 0 rg BT 217.66 185.10 Td (purchases. ) Tj ET Q q 0 0 0 rg BT 261.25 185.10 Td (As ) Tj ET Q q 0 0 0 rg BT 274.49 185.10 Td (a ) Tj ET Q q 0 0 0 rg BT 281.06 185.10 Td (result ) Tj ET Q q 0 0 0 rg BT 305.41 185.10 Td (of ) Tj ET Q q 0 0 0 rg BT 315.88 185.10 Td (the ) Tj ET Q q 0 0 0 rg BT 330.23 185.10 Td (Patient ) Tj ET Q q 0 0 0 rg BT 360.13 185.10 Td (Protection ) Tj ET Q q 0 0 0 rg BT 403.37 185.10 Td (and ) Tj ET Q q 0 0 0 rg BT 419.47 185.10 Td (Af) Tj ET Q q 0 0 0 rg BT 429.84 185.10 Td (fordable ) Tj ET Q q 0 0 0 rg BT 465.29 185.10 Td (Care ) Tj ET Q q 0 0 0 rg BT 485.83 185.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 502.40 185.10 Td (\(HR ) Tj ET Q q 0 0 0 rg BT 521.75 185.10 Td (3590\) ) Tj ET Q q 0 0 0 rg BT 547.22 185.10 Td (and ) Tj ET Q q 0 0 0 rg BT 563.79 185.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 173.10 Td (reconciliation ) Tj ET Q q 0 0 0 rg BT 93.81 173.10 Td (bill ) Tj ET Q q 0 0 0 rg BT 109.98 173.10 Td (containing ) Tj ET Q q 0 0 0 rg BT 155.02 173.10 Td (a ) Tj ET Q q 0 0 0 rg BT 162.29 173.10 Td (package ) Tj ET Q q 0 0 0 rg BT 197.88 173.10 Td (of ) Tj ET Q q 0 0 0 rg BT 209.05 173.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 244.09 173.10 Td (to ) Tj ET Q q 0 0 0 rg BT 254.70 173.10 Td (the ) Tj ET Q q 0 0 0 rg BT 269.75 173.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 313.66 173.10 Td (bill, ) Tj ET Q q 0 0 0 rg BT 332.33 173.10 Td (we ) Tj ET Q q 0 0 0 rg BT 346.82 173.10 Td (have ) Tj ET Q q 0 0 0 rg BT 368.53 173.10 Td (and ) Tj ET Q q 0 0 0 rg BT 385.81 173.10 Td (will ) Tj ET Q q 0 0 0 rg BT 404.20 173.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 441.46 173.10 Td (to ) Tj ET Q q 0 0 0 rg BT 452.07 173.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 498.21 173.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 541.03 173.10 Td (financial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 58.49 161.10 Td (and ) Tj ET Q q 0 0 0 rg BT 75.43 161.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 105.12 161.10 Td (other ) Tj ET Q q 0 0 0 rg BT 128.16 161.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 162.87 161.10 Td (to ) Tj ET Q q 0 0 0 rg BT 173.14 161.10 Td (our ) Tj ET Q q 0 0 0 rg BT 188.96 161.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 227.85 161.10 Td (For ) Tj ET Q q 0 0 0 rg BT 244.23 161.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 283.10 161.10 Td (minimum ) Tj ET Q q 0 0 0 rg BT 324.49 161.10 Td (rebates ) Tj ET Q q 0 0 0 rg BT 355.29 161.10 Td (on ) Tj ET Q q 0 0 0 rg BT 367.79 161.10 Td (our ) Tj ET Q q 0 0 0 rg BT 383.61 161.10 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 423.87 161.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 444.70 161.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 466.63 161.10 Td (have ) Tj ET Q q 0 0 0 rg BT 488.00 161.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 528.25 161.10 Td (from ) Tj ET Q q 0 0 0 rg BT 550.18 161.10 Td (15.1% ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 45.81 149.10 Td (23.1% ) Tj ET Q q 0 0 0 rg BT 73.67 149.10 Td (and ) Tj ET Q q 0 0 0 rg BT 90.15 149.10 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 129.94 149.10 Td (rebates ) Tj ET Q q 0 0 0 rg BT 160.29 149.10 Td (have ) Tj ET Q q 0 0 0 rg BT 181.20 149.10 Td (also ) Tj ET Q q 0 0 0 rg BT 199.34 149.10 Td (been ) Tj ET Q q 0 0 0 rg BT 220.25 149.10 Td (extended ) Tj ET Q q 0 0 0 rg BT 258.38 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 268.19 149.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 292.44 149.10 Td (used ) Tj ET Q q 0 0 0 rg BT 312.80 149.10 Td (in ) Tj ET Q q 0 0 0 rg BT 322.62 149.10 Td (risk-based ) Tj ET Q q 0 0 0 rg BT 365.75 149.10 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 405.54 149.10 Td (managed ) Tj ET Q q 0 0 0 rg BT 443.67 149.10 Td (care ) Tj ET Q q 0 0 0 rg BT 462.35 149.10 Td (plans. ) Tj ET Q q 0 0 0 rg BT 487.99 149.10 Td (In ) Tj ET Q q 0 0 0 rg BT 498.35 149.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 535.66 149.10 Td (we ) Tj ET Q q 0 0 0 rg BT 549.35 149.10 Td (extend ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.10 Td (discounts ) Tj ET Q q 0 0 0 rg BT 76.36 137.10 Td (to ) Tj ET Q q 0 0 0 rg BT 86.71 137.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 116.49 137.10 Td (critical ) Tj ET Q q 0 0 0 rg BT 146.83 137.10 Td (access ) Tj ET Q q 0 0 0 rg BT 174.95 137.10 Td (hospitals, ) Tj ET Q q 0 0 0 rg BT 215.58 137.10 Td (cancer ) Tj ET Q q 0 0 0 rg BT 244.24 137.10 Td (hospitals ) Tj ET Q q 0 0 0 rg BT 282.38 137.10 Td (and ) Tj ET Q q 0 0 0 rg BT 299.39 137.10 Td (other ) Tj ET Q q 0 0 0 rg BT 322.52 137.10 Td (covered ) Tj ET Q q 0 0 0 rg BT 356.74 137.10 Td (entities ) Tj ET Q q 0 0 0 rg BT 388.20 137.10 Td (as ) Tj ET Q q 0 0 0 rg BT 399.11 137.10 Td (required ) Tj ET Q q 0 0 0 rg BT 435.00 137.10 Td (by ) Tj ET Q q 0 0 0 rg BT 447.58 137.10 Td (the ) Tj ET Q q 0 0 0 rg BT 462.38 137.10 Td (expansion ) Tj ET Q q 0 0 0 rg BT 505.50 137.10 Td (of ) Tj ET Q q 0 0 0 rg BT 516.41 137.10 Td (the ) Tj ET Q q 0 0 0 rg BT 531.21 137.10 Td (340B ) Tj ET Q q 0 0 0 rg BT 555.45 137.10 Td (Drug ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (Pricing ) Tj ET Q q 0 0 0 rg BT 67.39 125.10 Td (Program ) Tj ET Q q 0 0 0 rg BT 104.33 125.10 Td (under ) Tj ET Q q 0 0 0 rg BT 129.59 125.10 Td (the ) Tj ET Q q 0 0 0 rg BT 144.31 125.10 Td (Public ) Tj ET Q q 0 0 0 rg BT 172.37 125.10 Td (Health ) Tj ET Q q 0 0 0 rg BT 201.52 125.10 Td (Service ) Tj ET Q q 0 0 0 rg BT 233.46 125.10 Td (Act.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 101.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.50 101.10 Td (are ) Tj ET Q q 0 0 0 rg BT 66.13 101.10 Td (required ) Tj ET Q q 0 0 0 rg BT 101.86 101.10 Td (to ) Tj ET Q q 0 0 0 rg BT 112.06 101.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 145.03 101.10 Td (a ) Tj ET Q q 0 0 0 rg BT 151.89 101.10 Td (50% ) Tj ET Q q 0 0 0 rg BT 172.65 101.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 208.95 101.10 Td (on ) Tj ET Q q 0 0 0 rg BT 221.38 101.10 Td (our ) Tj ET Q q 0 0 0 rg BT 237.13 101.10 Td (brand-name ) Tj ET Q q 0 0 0 rg BT 287.30 101.10 Td (drugs ) Tj ET Q q 0 0 0 rg BT 311.95 101.10 Td (to ) Tj ET Q q 0 0 0 rg BT 322.15 101.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 355.67 101.10 Td (who ) Tj ET Q q 0 0 0 rg BT 375.32 101.10 Td (fall ) Tj ET Q q 0 0 0 rg BT 391.06 101.10 Td (within ) Tj ET Q q 0 0 0 rg BT 419.04 101.10 Td (the ) Tj ET Q q 0 0 0 rg BT 433.68 101.10 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 473.86 101.10 Td (Part ) Tj ET Q q 0 0 0 rg BT 492.39 101.10 Td (D ) Tj ET Q q 0 0 0 rg BT 502.03 101.10 Td (coverage ) Tj ET Q q 0 0 0 rg BT 540.54 101.10 Td (gap, ) Tj ET Q q 0 0 0 rg BT 559.90 101.10 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 89.10 Td (referred ) Tj ET Q q 0 0 0 rg BT 69.88 89.10 Td (to ) Tj ET Q q 0 0 0 rg BT 79.90 89.10 Td (as ) Tj ET Q q 0 0 0 rg BT 90.48 89.10 Td (the ) Tj ET Q q 0 0 0 rg BT 104.94 89.10 Td (“donut ) Tj ET Q q 0 0 0 rg BT 134.40 89.10 Td (hole”, ) Tj ET Q q 0 0 0 rg BT 160.80 89.10 Td (and ) Tj ET Q q 0 0 0 rg BT 177.49 89.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 194.17 89.10 Td (an ) Tj ET Q q 0 0 0 rg BT 205.85 89.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 234.75 89.10 Td (non-tax-deductible ) Tj ET Q q 0 0 0 rg BT 312.53 89.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 326.98 89.10 Td (to ) Tj ET Q q 0 0 0 rg BT 337.00 89.10 Td (the ) Tj ET Q q 0 0 0 rg BT 351.46 89.10 Td (federal ) Tj ET Q q 0 0 0 rg BT 381.46 89.10 Td (government ) Tj ET Q q 0 0 0 rg BT 431.47 89.10 Td (based ) Tj ET Q q 0 0 0 rg BT 456.49 89.10 Td (on ) Tj ET Q q 0 0 0 rg BT 468.73 89.10 Td (an ) Tj ET Q q 0 0 0 rg BT 480.42 89.10 Td (allocation ) Tj ET Q q 0 0 0 rg BT 522.09 89.10 Td (of ) Tj ET Q q 0 0 0 rg BT 532.66 89.10 Td (our ) Tj ET Q q 0 0 0 rg BT 548.24 89.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 77.10 Td (share ) Tj ET Q q 0 0 0 rg BT 59.26 77.10 Td (of ) Tj ET Q q 0 0 0 rg BT 69.76 77.10 Td (branded ) Tj ET Q q 0 0 0 rg BT 104.13 77.10 Td (drug ) Tj ET Q q 0 0 0 rg BT 124.62 77.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 146.23 77.10 Td (to ) Tj ET Q q 0 0 0 rg BT 156.17 77.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 185.54 77.10 Td (government ) Tj ET Q q 0 0 0 rg BT 235.46 77.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 275.40 77.10 Td (including ) Tj ET Q q 0 0 0 rg BT 315.34 77.10 Td (Medicare, ) Tj ET Q q 0 0 0 rg BT 357.75 77.10 Td (Medicaid, ) Tj ET Q q 0 0 0 rg BT 400.18 77.10 Td (Department ) Tj ET Q q 0 0 0 rg BT 449.55 77.10 Td (of ) Tj ET Q q 0 0 0 rg BT 459.89 77.10 Td (V) Tj ET Q q 0 0 0 rg BT 466.00 77.10 Td (eterans ) Tj ET Q q 0 0 0 rg BT 496.00 77.10 Td (Af) Tj ET Q q 0 0 0 rg BT 506.37 77.10 Td (fairs, ) Tj ET Q q 0 0 0 rg BT 528.81 77.10 Td (Department ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 65.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.51 65.10 Td (Defense ) Tj ET Q q 0 0 0 rg BT 81.45 65.10 Td (and ) Tj ET Q q 0 0 0 rg BT 97.91 65.10 Td (TRICARE. ) Tj ET Q q 0 0 0 rg BT 145.21 65.10 Td (The ) Tj ET Q q 0 0 0 rg BT 162.93 65.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 195.11 65.10 Td (of ) Tj ET Q q 0 0 0 rg BT 205.62 65.10 Td (the ) Tj ET Q q 0 0 0 rg BT 220.01 65.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 248.85 65.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 263.23 65.10 Td (imposed ) Tj ET Q q 0 0 0 rg BT 299.30 65.10 Td (on ) Tj ET Q q 0 0 0 rg BT 311.48 65.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 374.73 65.10 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 434.10 65.10 Td (as ) Tj ET Q q 0 0 0 rg BT 444.61 65.10 Td (a ) Tj ET Q q 0 0 0 rg BT 451.23 65.10 Td (whole ) Tj ET Q q 0 0 0 rg BT 477.85 65.10 Td (was ) Tj ET Q q 0 0 0 rg BT 495.58 65.10 Td ($4.0 ) Tj ET Q q 0 0 0 rg BT 515.26 65.10 Td (billion ) Tj ET Q q 0 0 0 rg BT 543.55 65.10 Td (in ) Tj ET Q q 0 0 0 rg BT 553.51 65.10 Td (2017. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 53.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 53.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 76.55 53.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 91.25 53.10 Td (is ) Tj ET Q q 0 0 0 rg BT 100.42 53.10 Td ($4.1 ) Tj ET Q q 0 0 0 rg BT 120.42 53.10 Td (billion, ) Tj ET Q q 0 0 0 rg BT 151.54 53.10 Td (and ) Tj ET Q q 0 0 0 rg BT 168.48 53.10 Td (will ) Tj ET Q q 0 0 0 rg BT 186.53 53.10 Td (then ) Tj ET Q q 0 0 0 rg BT 206.25 53.10 Td (decrease ) Tj ET Q q 0 0 0 rg BT 243.16 53.10 Td (to ) Tj ET Q q 0 0 0 rg BT 253.44 53.10 Td ($2.8 ) Tj ET Q q 0 0 0 rg BT 273.44 53.10 Td (billion ) Tj ET Q q 0 0 0 rg BT 302.05 53.10 Td (in ) Tj ET Q q 0 0 0 rg BT 312.33 53.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 334.83 53.10 Td (and ) Tj ET Q q 0 0 0 rg BT 351.77 53.10 Td (thereafter) Tj ET Q q 0 0 0 rg BT 389.52 53.10 Td (.) Tj ET Q endstream endobj 33 0 obj <> endobj 34 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 56.06 749.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 96.66 749.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 130.05 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 146.78 749.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 169.07 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 185.78 749.10 Td (also ) Tj ET Q q 0 0 0 rg BT 206.39 749.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 239.22 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 251.51 749.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 297.11 749.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 353.82 749.10 Td (governing ) Tj ET Q q 0 0 0 rg BT 398.87 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 415.59 749.10 Td (testing, ) Tj ET Q q 0 0 0 rg BT 449.26 749.10 Td (approval, ) Tj ET Q q 0 0 0 rg BT 491.25 749.10 Td (safety) Tj ET Q q 0 0 0 rg BT 514.48 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 521.49 749.10 Td (ef) Tj ET Q q 0 0 0 rg BT 529.08 749.10 Td (fectiveness, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 99.94 737.10 Td (labeling ) Tj ET Q q 0 0 0 rg BT 135.29 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 152.85 737.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 196.53 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 207.99 737.10 Td (our ) Tj ET Q q 0 0 0 rg BT 224.45 737.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 264.29 737.10 Td (These ) Tj ET Q q 0 0 0 rg BT 291.30 737.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 335.53 737.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 390.86 737.10 Td (vary ) Tj ET Q q 0 0 0 rg BT 411.76 737.10 Td (from ) Tj ET Q q 0 0 0 rg BT 434.33 737.10 Td (country ) Tj ET Q q 0 0 0 rg BT 468.01 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 478.92 737.10 Td (country) Tj ET Q q 0 0 0 rg BT 508.82 737.10 Td (. ) Tj ET Q q 0 0 0 rg BT 514.22 737.10 Td (Whether ) Tj ET Q q 0 0 0 rg BT 551.78 737.10 Td (or ) Tj ET Q q 0 0 0 rg BT 563.24 737.10 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (FDA) Tj ET Q q 0 0 0 rg BT 55.45 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 57.89 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 68.66 725.10 Td (EC ) Tj ET Q q 0 0 0 rg BT 83.88 725.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 121.30 725.10 Td (has ) Tj ET Q q 0 0 0 rg BT 137.07 725.10 Td (been ) Tj ET Q q 0 0 0 rg BT 158.39 725.10 Td (obtained ) Tj ET Q q 0 0 0 rg BT 195.26 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 209.36 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 216.24 725.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 251.72 725.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 289.15 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 299.92 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 314.57 725.10 Td (product ) Tj ET Q q 0 0 0 rg BT 347.56 725.10 Td (by ) Tj ET Q q 0 0 0 rg BT 360.00 725.10 Td (comparable ) Tj ET Q q 0 0 0 rg BT 409.08 725.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 452.61 725.10 Td (authorities ) Tj ET Q q 0 0 0 rg BT 497.26 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 508.03 725.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 547.12 725.10 Td (outside ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.69 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 61.26 713.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 81.40 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 92.09 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 106.66 713.10 Td (EU, ) Tj ET Q q 0 0 0 rg BT 124.85 713.10 Td (as ) Tj ET Q q 0 0 0 rg BT 135.54 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 150.11 713.10 Td (case ) Tj ET Q q 0 0 0 rg BT 169.68 713.10 Td (may ) Tj ET Q q 0 0 0 rg BT 189.25 713.10 Td (be, ) Tj ET Q q 0 0 0 rg BT 203.55 713.10 Td (must ) Tj ET Q q 0 0 0 rg BT 225.35 713.10 Td (be ) Tj ET Q q 0 0 0 rg BT 237.15 713.10 Td (obtained ) Tj ET Q q 0 0 0 rg BT 273.94 713.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 295.74 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 305.87 713.10 Td (marketing ) Tj ET Q q 0 0 0 rg BT 348.77 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.35 713.10 Td (product ) Tj ET Q q 0 0 0 rg BT 396.25 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 406.39 713.10 Td (those ) Tj ET Q q 0 0 0 rg BT 429.85 713.10 Td (countries. ) Tj ET Q q 0 0 0 rg BT 471.19 713.10 Td (The ) Tj ET Q q 0 0 0 rg BT 489.10 713.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 526.44 713.10 Td (process ) Tj ET Q q 0 0 0 rg BT 558.79 713.10 Td (may ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (be ) Tj ET Q q 0 0 0 rg BT 48.22 701.10 Td (more ) Tj ET Q q 0 0 0 rg BT 71.55 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 82.67 701.10 Td (less ) Tj ET Q q 0 0 0 rg BT 100.45 701.10 Td (rigorous ) Tj ET Q q 0 0 0 rg BT 136.57 701.10 Td (from ) Tj ET Q q 0 0 0 rg BT 158.79 701.10 Td (country ) Tj ET Q q 0 0 0 rg BT 192.12 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 202.69 701.10 Td (country ) Tj ET Q q 0 0 0 rg BT 236.02 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 253.24 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 268.24 701.10 Td (time ) Tj ET Q q 0 0 0 rg BT 288.80 701.10 Td (required ) Tj ET Q q 0 0 0 rg BT 324.90 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 339.35 701.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 377.12 701.10 Td (may ) Tj ET Q q 0 0 0 rg BT 397.12 701.10 Td (be ) Tj ET Q q 0 0 0 rg BT 409.34 701.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 437.67 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 448.79 701.10 Td (shorter ) Tj ET Q q 0 0 0 rg BT 479.34 701.10 Td (than ) Tj ET Q q 0 0 0 rg BT 499.34 701.10 Td (that ) Tj ET Q q 0 0 0 rg BT 517.12 701.10 Td (required ) Tj ET Q q 0 0 0 rg BT 553.22 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 701.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 55.73 689.10 Td (Approval ) Tj ET Q q 0 0 0 rg BT 96.00 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 106.28 689.10 Td (one ) Tj ET Q q 0 0 0 rg BT 123.22 689.10 Td (country ) Tj ET Q q 0 0 0 rg BT 156.26 689.10 Td (does ) Tj ET Q q 0 0 0 rg BT 177.09 689.10 Td (not ) Tj ET Q q 0 0 0 rg BT 192.37 689.10 Td (assure ) Tj ET Q q 0 0 0 rg BT 219.86 689.10 Td (that ) Tj ET Q q 0 0 0 rg BT 237.36 689.10 Td (a ) Tj ET Q q 0 0 0 rg BT 244.30 689.10 Td (product ) Tj ET Q q 0 0 0 rg BT 277.34 689.10 Td (will ) Tj ET Q q 0 0 0 rg BT 295.40 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 307.34 689.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 347.04 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 357.32 689.10 Td (another ) Tj ET Q q 0 0 0 rg BT 389.81 689.10 Td (country) Tj ET Q q 0 0 0 rg BT 419.71 689.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (For ) Tj ET Q q 0 0 0 rg BT 52.74 665.10 Td (further ) Tj ET Q q 0 0 0 rg BT 82.80 665.10 Td (discussion ) Tj ET Q q 0 0 0 rg BT 127.32 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 138.50 665.10 Td (these ) Tj ET Q q 0 0 0 rg BT 161.90 665.10 Td (rebates ) Tj ET Q q 0 0 0 rg BT 193.06 665.10 Td (and ) Tj ET Q q 0 0 0 rg BT 210.35 665.10 Td (programs, ) Tj ET Q q 0 0 0 rg BT 253.47 665.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 275.19 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 285.82 665.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 311.43 665.10 Td (7. ) Tj ET Q q 0 0 0 rg BT 321.78 665.10 Td (Management’) Tj ET Q q 0 0 0 rg BT 376.76 665.10 Td (s ) Tj ET Q q 0 0 0 rg BT 383.51 665.10 Td (Discussion ) Tj ET Q q 0 0 0 rg BT 430.25 665.10 Td (and ) Tj ET Q q 0 0 0 rg BT 446.91 665.10 Td (Analysis ) Tj ET Q q 0 0 0 rg BT 484.76 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 495.94 665.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 536.00 665.10 Td (Condition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 653.10 Td (Results ) Tj ET Q q 0 0 0 rg BT 84.89 653.10 Td (of ) Tj ET Q q 0 0 0 rg BT 95.72 653.10 Td (Operations—GTN ) Tj ET Q q 0 0 0 rg BT 172.09 653.10 Td (Adjustments” ) Tj ET Q q 0 0 0 rg BT 229.59 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 246.53 653.10 Td (“—Critical ) Tj ET Q q 0 0 0 rg BT 292.90 653.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 342.06 653.10 Td (Policies.”) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (Sour) Tj ET Q q 0 0 0 rg BT 56.38 629.10 Td (ces and ) Tj ET Q q 0 0 0 rg BT 89.72 629.10 Td (A) Tj ET Q q 0 0 0 rg BT 96.20 629.10 Td (vailability of Raw Materials) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.24 605.10 Td (general, ) Tj ET Q q 0 0 0 rg BT 80.08 605.10 Td (we ) Tj ET Q q 0 0 0 rg BT 93.66 605.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 131.11 605.10 Td (our ) Tj ET Q q 0 0 0 rg BT 146.35 605.10 Td (raw ) Tj ET Q q 0 0 0 rg BT 163.26 605.10 Td (materials ) Tj ET Q q 0 0 0 rg BT 201.82 605.10 Td (and ) Tj ET Q q 0 0 0 rg BT 218.17 605.10 Td (supplies ) Tj ET Q q 0 0 0 rg BT 252.87 605.10 Td (required ) Tj ET Q q 0 0 0 rg BT 288.09 605.10 Td (for ) Tj ET Q q 0 0 0 rg BT 301.67 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 315.80 605.10 Td (production ) Tj ET Q q 0 0 0 rg BT 361.04 605.10 Td (of ) Tj ET Q q 0 0 0 rg BT 371.28 605.10 Td (our ) Tj ET Q q 0 0 0 rg BT 386.53 605.10 Td (products ) Tj ET Q q 0 0 0 rg BT 422.88 605.10 Td (in ) Tj ET Q q 0 0 0 rg BT 432.57 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 446.70 605.10 Td (open ) Tj ET Q q 0 0 0 rg BT 468.06 605.10 Td (market. ) Tj ET Q q 0 0 0 rg BT 500.23 605.10 Td (For ) Tj ET Q q 0 0 0 rg BT 516.04 605.10 Td (some ) Tj ET Q q 0 0 0 rg BT 539.06 605.10 Td (products, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (we ) Tj ET Q q 0 0 0 rg BT 49.65 593.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 87.17 593.10 Td (our ) Tj ET Q q 0 0 0 rg BT 102.49 593.10 Td (raw ) Tj ET Q q 0 0 0 rg BT 119.47 593.10 Td (materials ) Tj ET Q q 0 0 0 rg BT 158.11 593.10 Td (and ) Tj ET Q q 0 0 0 rg BT 174.54 593.10 Td (supplies ) Tj ET Q q 0 0 0 rg BT 209.31 593.10 Td (from ) Tj ET Q q 0 0 0 rg BT 230.73 593.10 Td (one ) Tj ET Q q 0 0 0 rg BT 247.16 593.10 Td (source ) Tj ET Q q 0 0 0 rg BT 275.25 593.10 Td (\(the ) Tj ET Q q 0 0 0 rg BT 292.78 593.10 Td (only ) Tj ET Q q 0 0 0 rg BT 312.55 593.10 Td (source ) Tj ET Q q 0 0 0 rg BT 340.64 593.10 Td (available ) Tj ET Q q 0 0 0 rg BT 378.72 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 388.48 593.10 Td (us\) ) Tj ET Q q 0 0 0 rg BT 402.69 593.10 Td (or ) Tj ET Q q 0 0 0 rg BT 413.01 593.10 Td (a ) Tj ET Q q 0 0 0 rg BT 419.44 593.10 Td (single ) Tj ET Q q 0 0 0 rg BT 445.31 593.10 Td (source ) Tj ET Q q 0 0 0 rg BT 473.40 593.10 Td (\(the ) Tj ET Q q 0 0 0 rg BT 490.94 593.10 Td (only ) Tj ET Q q 0 0 0 rg BT 510.71 593.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 549.90 593.10 Td (source ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (among ) Tj ET Q q 0 0 0 rg BT 65.77 581.10 Td (many ) Tj ET Q q 0 0 0 rg BT 90.54 581.10 Td (available ) Tj ET Q q 0 0 0 rg BT 129.19 581.10 Td (to ) Tj ET Q q 0 0 0 rg BT 139.52 581.10 Td (us\), ) Tj ET Q q 0 0 0 rg BT 156.80 581.10 Td (thereby ) Tj ET Q q 0 0 0 rg BT 189.34 581.10 Td (requiring ) Tj ET Q q 0 0 0 rg BT 228.55 581.10 Td (us ) Tj ET Q q 0 0 0 rg BT 240.00 581.10 Td (to ) Tj ET Q q 0 0 0 rg BT 250.33 581.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 277.88 581.10 Td (such ) Tj ET Q q 0 0 0 rg BT 298.77 581.10 Td (raw ) Tj ET Q q 0 0 0 rg BT 316.31 581.10 Td (materials ) Tj ET Q q 0 0 0 rg BT 355.52 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 372.51 581.10 Td (supplies ) Tj ET Q q 0 0 0 rg BT 407.84 581.10 Td (from ) Tj ET Q q 0 0 0 rg BT 429.84 581.10 Td (that ) Tj ET Q q 0 0 0 rg BT 447.39 581.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 488.25 581.10 Td (source. ) Tj ET Q q 0 0 0 rg BT 519.22 581.10 Td (W) Tj ET Q q 0 0 0 rg BT 527.86 581.10 Td (e ) Tj ET Q q 0 0 0 rg BT 534.85 581.10 Td (attempt, ) Tj ET Q q 0 0 0 rg BT 569.90 581.10 Td (if ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (possible, ) Tj ET Q q 0 0 0 rg BT 75.16 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 86.82 569.10 Td (mitigate ) Tj ET Q q 0 0 0 rg BT 123.46 569.10 Td (our ) Tj ET Q q 0 0 0 rg BT 140.67 569.10 Td (raw ) Tj ET Q q 0 0 0 rg BT 159.54 569.10 Td (material ) Tj ET Q q 0 0 0 rg BT 196.18 569.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 226.73 569.10 Td (risks, ) Tj ET Q q 0 0 0 rg BT 252.00 569.10 Td (through ) Tj ET Q q 0 0 0 rg BT 286.99 569.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 329.20 569.10 Td (management ) Tj ET Q q 0 0 0 rg BT 384.17 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 402.49 569.10 Td (alternative ) Tj ET Q q 0 0 0 rg BT 448.56 569.10 Td (sourcing ) Tj ET Q q 0 0 0 rg BT 486.88 569.10 Td (strategies. ) Tj ET Q q 0 0 0 rg BT 531.02 569.10 Td (For ) Tj ET Q q 0 0 0 rg BT 548.80 569.10 Td (further ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (discussion ) Tj ET Q q 0 0 0 rg BT 80.17 557.10 Td (of ) Tj ET Q q 0 0 0 rg BT 91.00 557.10 Td (sourcing, ) Tj ET Q q 0 0 0 rg BT 130.44 557.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 151.81 557.10 Td (to ) Tj ET Q q 0 0 0 rg BT 162.08 557.10 Td (“—Manufacturing ) Tj ET Q q 0 0 0 rg BT 238.45 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 255.38 557.10 Td (Quality ) Tj ET Q q 0 0 0 rg BT 287.33 557.10 Td (Assurance” ) Tj ET Q q 0 0 0 rg BT 335.92 557.10 Td (below ) Tj ET Q q 0 0 0 rg BT 362.86 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 379.79 557.10 Td (discussions ) Tj ET Q q 0 0 0 rg BT 427.86 557.10 Td (of ) Tj ET Q q 0 0 0 rg BT 438.69 557.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 479.50 557.10 Td (products.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (Manufacturing and Quality ) Tj ET Q q 0 0 0 rg BT 156.30 533.10 Td (Assurance) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 510.30 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 510.30 Td (e ) Tj ET Q q 0 0 0 rg BT 51.89 510.30 Td (operate ) Tj ET Q q 0 0 0 rg BT 84.12 510.30 Td (and ) Tj ET Q q 0 0 0 rg BT 101.37 510.30 Td (manage ) Tj ET Q q 0 0 0 rg BT 135.27 510.30 Td (our ) Tj ET Q q 0 0 0 rg BT 151.41 510.30 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 212.53 510.30 Td (network ) Tj ET Q q 0 0 0 rg BT 248.11 510.30 Td (in ) Tj ET Q q 0 0 0 rg BT 258.70 510.30 Td (a ) Tj ET Q q 0 0 0 rg BT 265.95 510.30 Td (manner ) Tj ET Q q 0 0 0 rg BT 298.74 510.30 Td (that ) Tj ET Q q 0 0 0 rg BT 316.55 510.30 Td (permits ) Tj ET Q q 0 0 0 rg BT 349.35 510.30 Td (us ) Tj ET Q q 0 0 0 rg BT 361.06 510.30 Td (to ) Tj ET Q q 0 0 0 rg BT 371.64 510.30 Td (improve ) Tj ET Q q 0 0 0 rg BT 407.78 510.30 Td (ef) Tj ET Q q 0 0 0 rg BT 415.37 510.30 Td (ficiency ) Tj ET Q q 0 0 0 rg BT 450.38 510.30 Td (while ) Tj ET Q q 0 0 0 rg BT 475.41 510.30 Td (maintaining ) Tj ET Q q 0 0 0 rg BT 525.99 510.30 Td (flexibility ) Tj ET Q q 0 0 0 rg BT 568.23 510.30 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 498.30 Td (reallocate ) Tj ET Q q 0 0 0 rg BT 77.21 498.30 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 137.88 498.30 Td (capacity) Tj ET Q q 0 0 0 rg BT 170.54 498.30 Td (. ) Tj ET Q q 0 0 0 rg BT 175.39 498.30 Td (Pharmaceutical ) Tj ET Q q 0 0 0 rg BT 239.38 498.30 Td (production ) Tj ET Q q 0 0 0 rg BT 285.06 498.30 Td (processes ) Tj ET Q q 0 0 0 rg BT 325.73 498.30 Td (are ) Tj ET Q q 0 0 0 rg BT 340.29 498.30 Td (complex, ) Tj ET Q q 0 0 0 rg BT 379.58 498.30 Td (highly ) Tj ET Q q 0 0 0 rg BT 407.49 498.30 Td (regulated ) Tj ET Q q 0 0 0 rg BT 447.04 498.30 Td (and ) Tj ET Q q 0 0 0 rg BT 463.84 498.30 Td (vary ) Tj ET Q q 0 0 0 rg BT 483.96 498.30 Td (widely ) Tj ET Q q 0 0 0 rg BT 513.53 498.30 Td (from ) Tj ET Q q 0 0 0 rg BT 535.32 498.30 Td (product ) Tj ET Q q 0 0 0 rg BT 568.22 498.30 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 486.30 Td (product. ) Tj ET Q q 0 0 0 rg BT 70.74 486.30 Td (Given ) Tj ET Q q 0 0 0 rg BT 96.87 486.30 Td (that ) Tj ET Q q 0 0 0 rg BT 113.56 486.30 Td (shifting ) Tj ET Q q 0 0 0 rg BT 145.80 486.30 Td (or ) Tj ET Q q 0 0 0 rg BT 155.83 486.30 Td (adding ) Tj ET Q q 0 0 0 rg BT 184.74 486.30 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 244.74 486.30 Td (capacity ) Tj ET Q q 0 0 0 rg BT 279.74 486.30 Td (can ) Tj ET Q q 0 0 0 rg BT 295.31 486.30 Td (be ) Tj ET Q q 0 0 0 rg BT 306.44 486.30 Td (a ) Tj ET Q q 0 0 0 rg BT 312.57 486.30 Td (lengthy ) Tj ET Q q 0 0 0 rg BT 344.26 486.30 Td (process ) Tj ET Q q 0 0 0 rg BT 375.94 486.30 Td (requiring ) Tj ET Q q 0 0 0 rg BT 414.29 486.30 Td (significant ) Tj ET Q q 0 0 0 rg BT 458.19 486.30 Td (capital ) Tj ET Q q 0 0 0 rg BT 486.53 486.30 Td (and ) Tj ET Q q 0 0 0 rg BT 502.66 486.30 Td (other ) Tj ET Q q 0 0 0 rg BT 524.90 486.30 Td (expenditures ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 474.30 Td (as ) Tj ET Q q 0 0 0 rg BT 46.10 474.30 Td (well ) Tj ET Q q 0 0 0 rg BT 65.09 474.30 Td (as ) Tj ET Q q 0 0 0 rg BT 75.19 474.30 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 118.05 474.30 Td (approvals, ) Tj ET Q q 0 0 0 rg BT 161.20 474.30 Td (we ) Tj ET Q q 0 0 0 rg BT 174.63 474.30 Td (maintain ) Tj ET Q q 0 0 0 rg BT 211.39 474.30 Td (and ) Tj ET Q q 0 0 0 rg BT 227.60 474.30 Td (operate ) Tj ET Q q 0 0 0 rg BT 258.79 474.30 Td (our ) Tj ET Q q 0 0 0 rg BT 273.89 474.30 Td (flexible ) Tj ET Q q 0 0 0 rg BT 306.20 474.30 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 366.28 474.30 Td (network, ) Tj ET Q q 0 0 0 rg BT 403.32 474.30 Td (consisting ) Tj ET Q q 0 0 0 rg BT 445.65 474.30 Td (of ) Tj ET Q q 0 0 0 rg BT 455.75 474.30 Td (internal ) Tj ET Q q 0 0 0 rg BT 488.06 474.30 Td (and ) Tj ET Q q 0 0 0 rg BT 504.27 474.30 Td (external ) Tj ET Q q 0 0 0 rg BT 538.24 474.30 Td (resources ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 462.30 Td (that ) Tj ET Q q 0 0 0 rg BT 52.61 462.30 Td (minimize ) Tj ET Q q 0 0 0 rg BT 91.99 462.30 Td (unnecessary ) Tj ET Q q 0 0 0 rg BT 142.47 462.30 Td (product ) Tj ET Q q 0 0 0 rg BT 174.63 462.30 Td (transfers ) Tj ET Q q 0 0 0 rg BT 210.67 462.30 Td (and ) Tj ET Q q 0 0 0 rg BT 226.72 462.30 Td (inef) Tj ET Q q 0 0 0 rg BT 242.09 462.30 Td (ficient ) Tj ET Q q 0 0 0 rg BT 269.24 462.30 Td (uses ) Tj ET Q q 0 0 0 rg BT 288.08 462.30 Td (of ) Tj ET Q q 0 0 0 rg BT 298.02 462.30 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 357.94 462.30 Td (capacity) Tj ET Q q 0 0 0 rg BT 390.60 462.30 Td (. ) Tj ET Q q 0 0 0 rg BT 394.72 462.30 Td (For ) Tj ET Q q 0 0 0 rg BT 410.22 462.30 Td (further ) Tj ET Q q 0 0 0 rg BT 439.04 462.30 Td (discussion ) Tj ET Q q 0 0 0 rg BT 482.32 462.30 Td (of ) Tj ET Q q 0 0 0 rg BT 492.27 462.30 Td (the ) Tj ET Q q 0 0 0 rg BT 506.10 462.30 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 548.80 462.30 Td (impact ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 450.30 Td (on ) Tj ET Q q 0 0 0 rg BT 48.50 450.30 Td (our ) Tj ET Q q 0 0 0 rg BT 64.33 450.30 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 127.64 450.30 Td (refer ) Tj ET Q q 0 0 0 rg BT 149.01 450.30 Td (to ) Tj ET Q q 0 0 0 rg BT 159.29 450.30 Td (“—Government ) Tj ET Q q 0 0 0 rg BT 226.21 450.30 Td (Regulation ) Tj ET Q q 0 0 0 rg BT 272.59 450.30 Td (and ) Tj ET Q q 0 0 0 rg BT 289.53 450.30 Td (Price ) Tj ET Q q 0 0 0 rg BT 312.58 450.30 Td (Constraints” ) Tj ET Q q 0 0 0 rg BT 365.07 450.30 Td (above.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 427.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.77 427.50 Td (significant ) Tj ET Q q 0 0 0 rg BT 100.19 427.50 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 164.48 427.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 226.01 427.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 263.65 427.50 Td (are ) Tj ET Q q 0 0 0 rg BT 279.07 427.50 Td (located ) Tj ET Q q 0 0 0 rg BT 311.16 427.50 Td (in ) Tj ET Q q 0 0 0 rg BT 322.15 427.50 Td (the ) Tj ET Q q 0 0 0 rg BT 337.58 427.50 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 361.08 427.50 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 390.40 427.50 Td (Rico, ) Tj ET Q q 0 0 0 rg BT 415.00 427.50 Td (France ) Tj ET Q q 0 0 0 rg BT 445.42 427.50 Td (and ) Tj ET Q q 0 0 0 rg BT 463.08 427.50 Td (Italy ) Tj ET Q q 0 0 0 rg BT 484.62 427.50 Td (and ) Tj ET Q q 0 0 0 rg BT 502.27 427.50 Td (require ) Tj ET Q q 0 0 0 rg BT 533.80 427.50 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 415.50 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 71.64 415.50 Td (capital ) Tj ET Q q 0 0 0 rg BT 101.14 415.50 Td (investment ) Tj ET Q q 0 0 0 rg BT 147.88 415.50 Td (for ) Tj ET Q q 0 0 0 rg BT 162.40 415.50 Td (both ) Tj ET Q q 0 0 0 rg BT 183.04 415.50 Td (maintenance ) Tj ET Q q 0 0 0 rg BT 236.42 415.50 Td (and ) Tj ET Q q 0 0 0 rg BT 253.72 415.50 Td (compliance ) Tj ET Q q 0 0 0 rg BT 302.67 415.50 Td (with ) Tj ET Q q 0 0 0 rg BT 323.30 415.50 Td (increasing ) Tj ET Q q 0 0 0 rg BT 367.25 415.50 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 411.21 415.50 Td (requirements. ) Tj ET Q q 0 0 0 rg BT 468.77 415.50 Td (In ) Tj ET Q q 0 0 0 rg BT 479.95 415.50 Td (addition, ) Tj ET Q q 0 0 0 rg BT 518.09 415.50 Td (as ) Tj ET Q q 0 0 0 rg BT 529.27 415.50 Td (our ) Tj ET Q q 0 0 0 rg BT 545.46 415.50 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 403.50 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 72.92 403.50 Td (changes ) Tj ET Q q 0 0 0 rg BT 107.05 403.50 Td (over ) Tj ET Q q 0 0 0 rg BT 126.75 403.50 Td (the ) Tj ET Q q 0 0 0 rg BT 140.89 403.50 Td (next ) Tj ET Q q 0 0 0 rg BT 160.03 403.50 Td (several ) Tj ET Q q 0 0 0 rg BT 190.27 403.50 Td (years, ) Tj ET Q q 0 0 0 rg BT 215.80 403.50 Td (we ) Tj ET Q q 0 0 0 rg BT 229.38 403.50 Td (expect ) Tj ET Q q 0 0 0 rg BT 257.40 403.50 Td (to ) Tj ET Q q 0 0 0 rg BT 267.10 403.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 303.46 403.50 Td (modification ) Tj ET Q q 0 0 0 rg BT 356.49 403.50 Td (of ) Tj ET Q q 0 0 0 rg BT 366.74 403.50 Td (our ) Tj ET Q q 0 0 0 rg BT 382.00 403.50 Td (existing ) Tj ET Q q 0 0 0 rg BT 415.59 403.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 475.82 403.50 Td (network ) Tj ET Q q 0 0 0 rg BT 510.52 403.50 Td (to ) Tj ET Q q 0 0 0 rg BT 520.22 403.50 Td (meet ) Tj ET Q q 0 0 0 rg BT 541.58 403.50 Td (complex ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 391.50 Td (processing ) Tj ET Q q 0 0 0 rg BT 81.48 391.50 Td (standards ) Tj ET Q q 0 0 0 rg BT 121.96 391.50 Td (that ) Tj ET Q q 0 0 0 rg BT 139.67 391.50 Td (may ) Tj ET Q q 0 0 0 rg BT 159.60 391.50 Td (be ) Tj ET Q q 0 0 0 rg BT 171.75 391.50 Td (required ) Tj ET Q q 0 0 0 rg BT 207.78 391.50 Td (for ) Tj ET Q q 0 0 0 rg BT 222.15 391.50 Td (newly ) Tj ET Q q 0 0 0 rg BT 249.30 391.50 Td (introduced ) Tj ET Q q 0 0 0 rg BT 294.78 391.50 Td (products, ) Tj ET Q q 0 0 0 rg BT 334.43 391.50 Td (including ) Tj ET Q q 0 0 0 rg BT 374.91 391.50 Td (biologics. ) Tj ET Q q 0 0 0 rg BT 416.79 391.50 Td (Biologics ) Tj ET Q q 0 0 0 rg BT 457.84 391.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 518.86 391.50 Td (involves ) Tj ET Q q 0 0 0 rg BT 555.46 391.50 Td (more ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 379.50 Td (complex ) Tj ET Q q 0 0 0 rg BT 72.91 379.50 Td (processes ) Tj ET Q q 0 0 0 rg BT 113.71 379.50 Td (than ) Tj ET Q q 0 0 0 rg BT 133.41 379.50 Td (those ) Tj ET Q q 0 0 0 rg BT 157.00 379.50 Td (of ) Tj ET Q q 0 0 0 rg BT 167.81 379.50 Td (traditional ) Tj ET Q q 0 0 0 rg BT 211.39 379.50 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 274.95 379.50 Td (operations. ) Tj ET Q q 0 0 0 rg BT 321.40 379.50 Td (The ) Tj ET Q q 0 0 0 rg BT 339.43 379.50 Td (FDA) Tj ET Q q 0 0 0 rg BT 358.88 379.50 Td ( ) Tj ET Q q 0 0 0 rg BT 361.36 379.50 Td (approved ) Tj ET Q q 0 0 0 rg BT 401.05 379.50 Td (our ) Tj ET Q q 0 0 0 rg BT 416.86 379.50 Td (lar) Tj ET Q q 0 0 0 rg BT 427.23 379.50 Td (ge ) Tj ET Q q 0 0 0 rg BT 439.15 379.50 Td (scale ) Tj ET Q q 0 0 0 rg BT 461.61 379.50 Td (multi-product ) Tj ET Q q 0 0 0 rg BT 519.08 379.50 Td (bulk ) Tj ET Q q 0 0 0 rg BT 539.34 379.50 Td (biologics ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 367.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 96.56 367.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 127.14 367.50 Td (in ) Tj ET Q q 0 0 0 rg BT 137.17 367.50 Td (Devens, ) Tj ET Q q 0 0 0 rg BT 171.91 367.50 Td (Massachusetts ) Tj ET Q q 0 0 0 rg BT 231.94 367.50 Td (in ) Tj ET Q q 0 0 0 rg BT 241.97 367.50 Td (May ) Tj ET Q q 0 0 0 rg BT 262.55 367.50 Td (2012 ) Tj ET Q q 0 0 0 rg BT 284.80 367.50 Td (and ) Tj ET Q q 0 0 0 rg BT 301.50 367.50 Td (we ) Tj ET Q q 0 0 0 rg BT 315.41 367.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 352.10 367.50 Td (to ) Tj ET Q q 0 0 0 rg BT 362.13 367.50 Td (make ) Tj ET Q q 0 0 0 rg BT 386.04 367.50 Td (capital ) Tj ET Q q 0 0 0 rg BT 414.94 367.50 Td (investments ) Tj ET Q q 0 0 0 rg BT 464.97 367.50 Td (in ) Tj ET Q q 0 0 0 rg BT 475.00 367.50 Td (this ) Tj ET Q q 0 0 0 rg BT 491.70 367.50 Td (facility) Tj ET Q q 0 0 0 rg BT 519.37 367.50 Td (. ) Tj ET Q q 0 0 0 rg BT 523.96 367.50 Td (W) Tj ET Q q 0 0 0 rg BT 532.60 367.50 Td (e ) Tj ET Q q 0 0 0 rg BT 539.29 367.50 Td (are ) Tj ET Q q 0 0 0 rg BT 553.75 367.50 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 367.50 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 355.50 Td (startup ) Tj ET Q q 0 0 0 rg BT 65.50 355.50 Td (phase ) Tj ET Q q 0 0 0 rg BT 90.56 355.50 Td (of ) Tj ET Q q 0 0 0 rg BT 101.17 355.50 Td (our ) Tj ET Q q 0 0 0 rg BT 116.79 355.50 Td (new ) Tj ET Q q 0 0 0 rg BT 135.73 355.50 Td (lar) Tj ET Q q 0 0 0 rg BT 146.10 355.50 Td (ge-scale ) Tj ET Q q 0 0 0 rg BT 181.14 355.50 Td (biologics ) Tj ET Q q 0 0 0 rg BT 220.09 355.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 280.68 355.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 311.29 355.50 Td (in ) Tj ET Q q 0 0 0 rg BT 321.35 355.50 Td (Cruiserath, ) Tj ET Q q 0 0 0 rg BT 367.79 355.50 Td (Ireland, ) Tj ET Q q 0 0 0 rg BT 400.89 355.50 Td (which ) Tj ET Q q 0 0 0 rg BT 427.62 355.50 Td (is ) Tj ET Q q 0 0 0 rg BT 436.57 355.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 474.39 355.50 Td (to ) Tj ET Q q 0 0 0 rg BT 484.45 355.50 Td (be ) Tj ET Q q 0 0 0 rg BT 496.18 355.50 Td (operational ) Tj ET Q q 0 0 0 rg BT 543.44 355.50 Td (in ) Tj ET Q q 0 0 0 rg BT 553.50 355.50 Td (2019.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 332.70 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 332.70 Td (e ) Tj ET Q q 0 0 0 rg BT 51.29 332.70 Td (rely ) Tj ET Q q 0 0 0 rg BT 69.06 332.70 Td (on ) Tj ET Q q 0 0 0 rg BT 81.27 332.70 Td (third ) Tj ET Q q 0 0 0 rg BT 102.38 332.70 Td (parties ) Tj ET Q q 0 0 0 rg BT 131.25 332.70 Td (to ) Tj ET Q q 0 0 0 rg BT 141.24 332.70 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 193.43 332.70 Td (or ) Tj ET Q q 0 0 0 rg BT 203.98 332.70 Td (supply ) Tj ET Q q 0 0 0 rg BT 232.87 332.70 Td (us ) Tj ET Q q 0 0 0 rg BT 243.97 332.70 Td (with ) Tj ET Q q 0 0 0 rg BT 263.97 332.70 Td (all ) Tj ET Q q 0 0 0 rg BT 276.18 332.70 Td (or ) Tj ET Q q 0 0 0 rg BT 286.73 332.70 Td (a ) Tj ET Q q 0 0 0 rg BT 293.38 332.70 Td (portion ) Tj ET Q q 0 0 0 rg BT 324.49 332.70 Td (of ) Tj ET Q q 0 0 0 rg BT 335.03 332.70 Td (the ) Tj ET Q q 0 0 0 rg BT 349.47 332.70 Td (active ) Tj ET Q q 0 0 0 rg BT 375.56 332.70 Td (product ) Tj ET Q q 0 0 0 rg BT 408.32 332.70 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 451.08 332.70 Td (or ) Tj ET Q q 0 0 0 rg BT 461.63 332.70 Td (drug ) Tj ET Q q 0 0 0 rg BT 482.17 332.70 Td (substance ) Tj ET Q q 0 0 0 rg BT 523.27 332.70 Td (necessary ) Tj ET Q q 0 0 0 rg BT 564.35 332.70 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 320.70 Td (us ) Tj ET Q q 0 0 0 rg BT 47.66 320.70 Td (to ) Tj ET Q q 0 0 0 rg BT 58.20 320.70 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 110.93 320.70 Td (various ) Tj ET Q q 0 0 0 rg BT 143.13 320.70 Td (products, ) Tj ET Q q 0 0 0 rg BT 182.84 320.70 Td (such ) Tj ET Q q 0 0 0 rg BT 203.93 320.70 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 215.02 320.70 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 244.46 320.70 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 249.73 320.70 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 279.71 320.70 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 284.97 320.70 Td (Y) Tj ET Q q 0 0 0 rg BT 289.62 320.70 Td (ervoy) Tj ET Q q 0 0 0 rg BT 311.27 320.70 Td (, ) Tj ET Q q 0 0 0 rg BT 316.54 320.70 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.87 320.70 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 350.14 320.70 Td (Or) Tj ET Q q 0 0 0 rg BT 360.88 320.70 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.53 320.70 Td (,) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 385.03 320.70 Td ( ) Tj ET Q q 0 0 0 rg BT 387.80 320.70 Td (Baraclude) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.45 320.70 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 434.72 320.70 Td (Reyataz ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.13 320.70 Td (and ) Tj ET Q q 0 0 0 rg BT 486.34 320.70 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 501.32 320.70 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 530.20 320.70 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 532.97 320.70 Td (Franchise, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 308.70 Td (and ) Tj ET Q q 0 0 0 rg BT 52.49 308.70 Td (we ) Tj ET Q q 0 0 0 rg BT 66.20 308.70 Td (continue ) Tj ET Q q 0 0 0 rg BT 102.69 308.70 Td (to ) Tj ET Q q 0 0 0 rg BT 112.52 308.70 Td (shift ) Tj ET Q q 0 0 0 rg BT 132.35 308.70 Td (towards ) Tj ET Q q 0 0 0 rg BT 166.06 308.70 Td (using ) Tj ET Q q 0 0 0 rg BT 189.78 308.70 Td (third ) Tj ET Q q 0 0 0 rg BT 210.72 308.70 Td (party ) Tj ET Q q 0 0 0 rg BT 233.32 308.70 Td (manufactures ) Tj ET Q q 0 0 0 rg BT 289.24 308.70 Td (for ) Tj ET Q q 0 0 0 rg BT 302.95 308.70 Td (supply ) Tj ET Q q 0 0 0 rg BT 331.67 308.70 Td (of ) Tj ET Q q 0 0 0 rg BT 342.05 308.70 Td (our ) Tj ET Q q 0 0 0 rg BT 357.44 308.70 Td (established ) Tj ET Q q 0 0 0 rg BT 403.92 308.70 Td (brands) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 430.58 308.70 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.08 308.70 Td ( ) Tj ET Q q 0 0 0 rg BT 434.99 308.70 Td (T) Tj ET Q q 0 0 0 rg BT 440.40 308.70 Td (o ) Tj ET Q q 0 0 0 rg BT 447.45 308.70 Td (maintain ) Tj ET Q q 0 0 0 rg BT 484.49 308.70 Td (a ) Tj ET Q q 0 0 0 rg BT 490.98 308.70 Td (stable ) Tj ET Q q 0 0 0 rg BT 516.36 308.70 Td (supply ) Tj ET Q q 0 0 0 rg BT 545.08 308.70 Td (of ) Tj ET Q q 0 0 0 rg BT 555.46 308.70 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 296.70 Td (products, ) Tj ET Q q 0 0 0 rg BT 76.31 296.70 Td (we ) Tj ET Q q 0 0 0 rg BT 91.35 296.70 Td (take ) Tj ET Q q 0 0 0 rg BT 111.38 296.70 Td (a ) Tj ET Q q 0 0 0 rg BT 119.20 296.70 Td (variety ) Tj ET Q q 0 0 0 rg BT 150.34 296.70 Td (of ) Tj ET Q q 0 0 0 rg BT 162.04 296.70 Td (actions ) Tj ET Q q 0 0 0 rg BT 193.75 296.70 Td (including ) Tj ET Q q 0 0 0 rg BT 234.90 296.70 Td (inventory ) Tj ET Q q 0 0 0 rg BT 276.60 296.70 Td (management ) Tj ET Q q 0 0 0 rg BT 331.06 296.70 Td (and ) Tj ET Q q 0 0 0 rg BT 348.88 296.70 Td (maintenance ) Tj ET Q q 0 0 0 rg BT 402.78 296.70 Td (of ) Tj ET Q q 0 0 0 rg BT 414.49 296.70 Td (additional ) Tj ET Q q 0 0 0 rg BT 457.86 296.70 Td (quantities ) Tj ET Q q 0 0 0 rg BT 500.11 296.70 Td (of ) Tj ET Q q 0 0 0 rg BT 511.82 296.70 Td (materials, ) Tj ET Q q 0 0 0 rg BT 554.35 296.70 Td (when ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 284.70 Td (possible, ) Tj ET Q q 0 0 0 rg BT 74.36 284.70 Td (designed ) Tj ET Q q 0 0 0 rg BT 112.98 284.70 Td (to ) Tj ET Q q 0 0 0 rg BT 123.84 284.70 Td (provide ) Tj ET Q q 0 0 0 rg BT 157.46 284.70 Td (for ) Tj ET Q q 0 0 0 rg BT 172.20 284.70 Td (a ) Tj ET Q q 0 0 0 rg BT 179.72 284.70 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 225.55 284.70 Td (level ) Tj ET Q q 0 0 0 rg BT 248.07 284.70 Td (of ) Tj ET Q q 0 0 0 rg BT 259.47 284.70 Td (these ) Tj ET Q q 0 0 0 rg BT 283.10 284.70 Td (ingredients ) Tj ET Q q 0 0 0 rg BT 330.61 284.70 Td (to ) Tj ET Q q 0 0 0 rg BT 341.47 284.70 Td (be ) Tj ET Q q 0 0 0 rg BT 353.99 284.70 Td (held ) Tj ET Q q 0 0 0 rg BT 374.28 284.70 Td (by ) Tj ET Q q 0 0 0 rg BT 387.36 284.70 Td (the ) Tj ET Q q 0 0 0 rg BT 402.66 284.70 Td (third-party ) Tj ET Q q 0 0 0 rg BT 448.50 284.70 Td (supplier) Tj ET Q q 0 0 0 rg BT 480.31 284.70 Td (, ) Tj ET Q q 0 0 0 rg BT 485.89 284.70 Td (us ) Tj ET Q q 0 0 0 rg BT 497.86 284.70 Td (or ) Tj ET Q q 0 0 0 rg BT 509.27 284.70 Td (both, ) Tj ET Q q 0 0 0 rg BT 532.63 284.70 Td (so ) Tj ET Q q 0 0 0 rg BT 544.60 284.70 Td (that ) Tj ET Q q 0 0 0 rg BT 562.67 284.70 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 272.70 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 95.86 272.70 Td (operations ) Tj ET Q q 0 0 0 rg BT 139.06 272.70 Td (are ) Tj ET Q q 0 0 0 rg BT 152.82 272.70 Td (not ) Tj ET Q q 0 0 0 rg BT 167.14 272.70 Td (interrupted. ) Tj ET Q q 0 0 0 rg BT 215.06 272.70 Td (Certain ) Tj ET Q q 0 0 0 rg BT 246.04 272.70 Td (supply ) Tj ET Q q 0 0 0 rg BT 274.26 272.70 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 329.67 272.70 Td (extend ) Tj ET Q q 0 0 0 rg BT 357.88 272.70 Td (over ) Tj ET Q q 0 0 0 rg BT 377.19 272.70 Td (multiple ) Tj ET Q q 0 0 0 rg BT 412.07 272.70 Td (years ) Tj ET Q q 0 0 0 rg BT 434.72 272.70 Td (with ) Tj ET Q q 0 0 0 rg BT 454.04 272.70 Td (minimum ) Tj ET Q q 0 0 0 rg BT 494.48 272.70 Td (purchase ) Tj ET Q q 0 0 0 rg BT 531.57 272.70 Td (obligations ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 260.70 Td (determined ) Tj ET Q q 0 0 0 rg BT 83.08 260.70 Td (using ) Tj ET Q q 0 0 0 rg BT 106.84 260.70 Td (expected ) Tj ET Q q 0 0 0 rg BT 144.47 260.70 Td (near ) Tj ET Q q 0 0 0 rg BT 163.77 260.70 Td (or ) Tj ET Q q 0 0 0 rg BT 174.19 260.70 Td (long-term ) Tj ET Q q 0 0 0 rg BT 215.72 260.70 Td (demand ) Tj ET Q q 0 0 0 rg BT 249.47 260.70 Td (requirements. ) Tj ET Q q 0 0 0 rg BT 305.81 260.70 Td (As ) Tj ET Q q 0 0 0 rg BT 319.01 260.70 Td (an ) Tj ET Q q 0 0 0 rg BT 330.55 260.70 Td (additional ) Tj ET Q q 0 0 0 rg BT 372.63 260.70 Td (protection, ) Tj ET Q q 0 0 0 rg BT 417.77 260.70 Td (in ) Tj ET Q q 0 0 0 rg BT 427.64 260.70 Td (some ) Tj ET Q q 0 0 0 rg BT 450.85 260.70 Td (cases, ) Tj ET Q q 0 0 0 rg BT 476.54 260.70 Td (we ) Tj ET Q q 0 0 0 rg BT 490.29 260.70 Td (take ) Tj ET Q q 0 0 0 rg BT 509.04 260.70 Td (steps ) Tj ET Q q 0 0 0 rg BT 531.14 260.70 Td (to ) Tj ET Q q 0 0 0 rg BT 541.01 260.70 Td (maintain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 248.70 Td (an ) Tj ET Q q 0 0 0 rg BT 49.03 248.70 Td (approved ) Tj ET Q q 0 0 0 rg BT 89.83 248.70 Td (back-up ) Tj ET Q q 0 0 0 rg BT 125.63 248.70 Td (source ) Tj ET Q q 0 0 0 rg BT 155.32 248.70 Td (where ) Tj ET Q q 0 0 0 rg BT 183.34 248.70 Td (available. ) Tj ET Q q 0 0 0 rg BT 225.53 248.70 Td (For ) Tj ET Q q 0 0 0 rg BT 243.01 248.70 Td (example, ) Tj ET Q q 0 0 0 rg BT 282.97 248.70 Td (we ) Tj ET Q q 0 0 0 rg BT 298.23 248.70 Td (have ) Tj ET Q q 0 0 0 rg BT 320.70 248.70 Td (the ) Tj ET Q q 0 0 0 rg BT 336.51 248.70 Td (capability ) Tj ET Q q 0 0 0 rg BT 379.53 248.70 Td (to ) Tj ET Q q 0 0 0 rg BT 390.90 248.70 Td (manufacture ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 444.46 248.70 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.90 248.70 Td ( ) Tj ET Q q 0 0 0 rg BT 477.49 248.70 Td (internally ) Tj ET Q q 0 0 0 rg BT 519.41 248.70 Td (and ) Tj ET Q q 0 0 0 rg BT 537.44 248.70 Td (also ) Tj ET Q q 0 0 0 rg BT 557.14 248.70 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 236.70 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 92.36 236.70 Td (with ) Tj ET Q q 0 0 0 rg BT 112.64 236.70 Td (third-party ) Tj ET Q q 0 0 0 rg BT 157.90 236.70 Td (manufacturers ) Tj ET Q q 0 0 0 rg BT 217.60 236.70 Td (to ) Tj ET Q q 0 0 0 rg BT 227.88 236.70 Td (meet ) Tj ET Q q 0 0 0 rg BT 249.81 236.70 Td (demand. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.90 Td (In ) Tj ET Q q 0 0 0 rg BT 48.65 213.90 Td (connection ) Tj ET Q q 0 0 0 rg BT 96.85 213.90 Td (with ) Tj ET Q q 0 0 0 rg BT 118.95 213.90 Td (divestitures, ) Tj ET Q q 0 0 0 rg BT 171.88 213.90 Td (licensing ) Tj ET Q q 0 0 0 rg BT 212.30 213.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 270.49 213.90 Td (or ) Tj ET Q q 0 0 0 rg BT 283.14 213.90 Td (distribution ) Tj ET Q q 0 0 0 rg BT 333.58 213.90 Td (agreements ) Tj ET Q q 0 0 0 rg BT 383.43 213.90 Td (of ) Tj ET Q q 0 0 0 rg BT 396.08 213.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 427.61 213.90 Td (of ) Tj ET Q q 0 0 0 rg BT 440.26 213.90 Td (our ) Tj ET Q q 0 0 0 rg BT 457.91 213.90 Td (products, ) Tj ET Q q 0 0 0 rg BT 499.17 213.90 Td (or ) Tj ET Q q 0 0 0 rg BT 511.83 213.90 Td (in ) Tj ET Q q 0 0 0 rg BT 523.93 213.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 555.45 213.90 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.90 Td (circumstances, ) Tj ET Q q 0 0 0 rg BT 98.32 201.90 Td (we ) Tj ET Q q 0 0 0 rg BT 113.15 201.90 Td (have ) Tj ET Q q 0 0 0 rg BT 135.20 201.90 Td (entered ) Tj ET Q q 0 0 0 rg BT 167.80 201.90 Td (into ) Tj ET Q q 0 0 0 rg BT 186.53 201.90 Td (agreements ) Tj ET Q q 0 0 0 rg BT 235.24 201.90 Td (under ) Tj ET Q q 0 0 0 rg BT 261.19 201.90 Td (which ) Tj ET Q q 0 0 0 rg BT 288.80 201.90 Td (we ) Tj ET Q q 0 0 0 rg BT 303.64 201.90 Td (have ) Tj ET Q q 0 0 0 rg BT 325.69 201.90 Td (agreed ) Tj ET Q q 0 0 0 rg BT 355.51 201.90 Td (to ) Tj ET Q q 0 0 0 rg BT 366.46 201.90 Td (supply ) Tj ET Q q 0 0 0 rg BT 396.31 201.90 Td (such ) Tj ET Q q 0 0 0 rg BT 417.81 201.90 Td (products ) Tj ET Q q 0 0 0 rg BT 455.43 201.90 Td (to ) Tj ET Q q 0 0 0 rg BT 466.38 201.90 Td (third ) Tj ET Q q 0 0 0 rg BT 488.44 201.90 Td (parties. ) Tj ET Q q 0 0 0 rg BT 520.77 201.90 Td (In ) Tj ET Q q 0 0 0 rg BT 532.28 201.90 Td (addition ) Tj ET Q q 0 0 0 rg BT 568.23 201.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.90 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 75.82 189.90 Td (that ) Tj ET Q q 0 0 0 rg BT 93.42 189.90 Td (could ) Tj ET Q q 0 0 0 rg BT 118.24 189.90 Td (arise ) Tj ET Q q 0 0 0 rg BT 139.73 189.90 Td (from ) Tj ET Q q 0 0 0 rg BT 161.77 189.90 Td (our ) Tj ET Q q 0 0 0 rg BT 177.70 189.90 Td (failure ) Tj ET Q q 0 0 0 rg BT 206.40 189.90 Td (to ) Tj ET Q q 0 0 0 rg BT 216.79 189.90 Td (supply ) Tj ET Q q 0 0 0 rg BT 246.06 189.90 Td (such ) Tj ET Q q 0 0 0 rg BT 267.00 189.90 Td (products ) Tj ET Q q 0 0 0 rg BT 304.04 189.90 Td (under ) Tj ET Q q 0 0 0 rg BT 329.41 189.90 Td (the ) Tj ET Q q 0 0 0 rg BT 344.23 189.90 Td (agreements, ) Tj ET Q q 0 0 0 rg BT 394.87 189.90 Td (these ) Tj ET Q q 0 0 0 rg BT 418.02 189.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 474.49 189.90 Td (could ) Tj ET Q q 0 0 0 rg BT 499.31 189.90 Td (require ) Tj ET Q q 0 0 0 rg BT 530.23 189.90 Td (us ) Tj ET Q q 0 0 0 rg BT 541.73 189.90 Td (to ) Tj ET Q q 0 0 0 rg BT 552.11 189.90 Td (invest ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 177.90 Td (in ) Tj ET Q q 0 0 0 rg BT 46.02 177.90 Td (facilities ) Tj ET Q q 0 0 0 rg BT 82.70 177.90 Td (for ) Tj ET Q q 0 0 0 rg BT 96.60 177.90 Td (the ) Tj ET Q q 0 0 0 rg BT 111.06 177.90 Td (production ) Tj ET Q q 0 0 0 rg BT 156.63 177.90 Td (of ) Tj ET Q q 0 0 0 rg BT 167.21 177.90 Td (non-strategic ) Tj ET Q q 0 0 0 rg BT 221.66 177.90 Td (products, ) Tj ET Q q 0 0 0 rg BT 260.84 177.90 Td (result ) Tj ET Q q 0 0 0 rg BT 285.30 177.90 Td (in ) Tj ET Q q 0 0 0 rg BT 295.33 177.90 Td (additional ) Tj ET Q q 0 0 0 rg BT 337.56 177.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 380.90 177.90 Td (filings ) Tj ET Q q 0 0 0 rg BT 408.70 177.90 Td (and ) Tj ET Q q 0 0 0 rg BT 425.39 177.90 Td (obligations ) Tj ET Q q 0 0 0 rg BT 472.07 177.90 Td (or ) Tj ET Q q 0 0 0 rg BT 482.65 177.90 Td (cause ) Tj ET Q q 0 0 0 rg BT 507.10 177.90 Td (an ) Tj ET Q q 0 0 0 rg BT 518.79 177.90 Td (interruption ) Tj ET Q q 0 0 0 rg BT 568.24 177.90 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 165.90 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 165.90 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 111.53 165.90 Td (of ) Tj ET Q q 0 0 0 rg BT 122.36 165.90 Td (our ) Tj ET Q q 0 0 0 rg BT 138.19 165.90 Td (own ) Tj ET Q q 0 0 0 rg BT 157.91 165.90 Td (products.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 143.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.54 143.10 Td (success ) Tj ET Q q 0 0 0 rg BT 85.52 143.10 Td (depends ) Tj ET Q q 0 0 0 rg BT 120.27 143.10 Td (in ) Tj ET Q q 0 0 0 rg BT 130.04 143.10 Td (great ) Tj ET Q q 0 0 0 rg BT 152.01 143.10 Td (measure ) Tj ET Q q 0 0 0 rg BT 187.31 143.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 209.30 143.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 247.94 143.10 Td (confidence ) Tj ET Q q 0 0 0 rg BT 293.79 143.10 Td (in ) Tj ET Q q 0 0 0 rg BT 303.56 143.10 Td (the ) Tj ET Q q 0 0 0 rg BT 317.76 143.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 347.52 143.10 Td (of ) Tj ET Q q 0 0 0 rg BT 357.84 143.10 Td (our ) Tj ET Q q 0 0 0 rg BT 373.16 143.10 Td (products ) Tj ET Q q 0 0 0 rg BT 409.58 143.10 Td (and ) Tj ET Q q 0 0 0 rg BT 426.01 143.10 Td (in ) Tj ET Q q 0 0 0 rg BT 435.78 143.10 Td (the ) Tj ET Q q 0 0 0 rg BT 449.98 143.10 Td (integrity ) Tj ET Q q 0 0 0 rg BT 485.85 143.10 Td (of ) Tj ET Q q 0 0 0 rg BT 496.17 143.10 Td (the ) Tj ET Q q 0 0 0 rg BT 510.37 143.10 Td (data ) Tj ET Q q 0 0 0 rg BT 529.01 143.10 Td (that ) Tj ET Q q 0 0 0 rg BT 546.00 143.10 Td (support ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 131.10 Td (their ) Tj ET Q q 0 0 0 rg BT 56.59 131.10 Td (safety ) Tj ET Q q 0 0 0 rg BT 82.74 131.10 Td (and ) Tj ET Q q 0 0 0 rg BT 99.44 131.10 Td (ef) Tj ET Q q 0 0 0 rg BT 107.03 131.10 Td (fectiveness. ) Tj ET Q q 0 0 0 rg BT 156.22 131.10 Td (Product ) Tj ET Q q 0 0 0 rg BT 189.60 131.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 219.64 131.10 Td (arises ) Tj ET Q q 0 0 0 rg BT 244.67 131.10 Td (from ) Tj ET Q q 0 0 0 rg BT 266.38 131.10 Td (a ) Tj ET Q q 0 0 0 rg BT 273.08 131.10 Td (total ) Tj ET Q q 0 0 0 rg BT 293.12 131.10 Td (commitment ) Tj ET Q q 0 0 0 rg BT 345.94 131.10 Td (to ) Tj ET Q q 0 0 0 rg BT 355.98 131.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 386.02 131.10 Td (in ) Tj ET Q q 0 0 0 rg BT 396.07 131.10 Td (all ) Tj ET Q q 0 0 0 rg BT 408.33 131.10 Td (parts ) Tj ET Q q 0 0 0 rg BT 430.04 131.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.63 131.10 Td (our ) Tj ET Q q 0 0 0 rg BT 456.23 131.10 Td (operations, ) Tj ET Q q 0 0 0 rg BT 502.65 131.10 Td (including ) Tj ET Q q 0 0 0 rg BT 542.69 131.10 Td (research ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 119.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.16 119.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 110.04 119.10 Td (purchasing, ) Tj ET Q q 0 0 0 rg BT 159.14 119.10 Td (facilities ) Tj ET Q q 0 0 0 rg BT 196.29 119.10 Td (planning, ) Tj ET Q q 0 0 0 rg BT 236.51 119.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 300.05 119.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.21 119.10 Td (distribution. ) Tj ET Q q 0 0 0 rg BT 368.35 119.10 Td (W) Tj ET Q q 0 0 0 rg BT 376.99 119.10 Td (e ) Tj ET Q q 0 0 0 rg BT 384.15 119.10 Td (maintain ) Tj ET Q q 0 0 0 rg BT 421.87 119.10 Td (records ) Tj ET Q q 0 0 0 rg BT 454.02 119.10 Td (to ) Tj ET Q q 0 0 0 rg BT 464.52 119.10 Td (demonstrate ) Tj ET Q q 0 0 0 rg BT 516.12 119.10 Td (the ) Tj ET Q q 0 0 0 rg BT 531.06 119.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 561.56 119.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 107.10 Td (integrity ) Tj ET Q q 0 0 0 rg BT 72.38 107.10 Td (of ) Tj ET Q q 0 0 0 rg BT 83.21 107.10 Td (technical ) Tj ET Q q 0 0 0 rg BT 121.80 107.10 Td (information ) Tj ET Q q 0 0 0 rg BT 171.51 107.10 Td (and ) Tj ET Q q 0 0 0 rg BT 188.45 107.10 Td (production ) Tj ET Q q 0 0 0 rg BT 234.28 107.10 Td (processes.) Tj ET Q endstream endobj 35 0 obj <> endobj 36 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Control ) Tj ET Q q 0 0 0 rg BT 68.23 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 78.24 749.10 Td (production ) Tj ET Q q 0 0 0 rg BT 123.24 749.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 163.24 749.10 Td (involves ) Tj ET Q q 0 0 0 rg BT 198.81 749.10 Td (established ) Tj ET Q q 0 0 0 rg BT 244.92 749.10 Td (specifications ) Tj ET Q q 0 0 0 rg BT 301.57 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.69 749.10 Td (standards ) Tj ET Q q 0 0 0 rg BT 357.14 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 370.47 749.10 Td (ingredients, ) Tj ET Q q 0 0 0 rg BT 419.08 749.10 Td (equipment ) Tj ET Q q 0 0 0 rg BT 462.97 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 479.09 749.10 Td (facilities, ) Tj ET Q q 0 0 0 rg BT 517.69 749.10 Td (manufacturing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (methods, ) Tj ET Q q 0 0 0 rg BT 73.99 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 90.04 737.10 Td (operations, ) Tj ET Q q 0 0 0 rg BT 135.80 737.10 Td (packaging ) Tj ET Q q 0 0 0 rg BT 178.50 737.10 Td (materials ) Tj ET Q q 0 0 0 rg BT 216.76 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 232.80 737.10 Td (labeling. ) Tj ET Q q 0 0 0 rg BT 269.00 737.10 Td (W) Tj ET Q q 0 0 0 rg BT 277.64 737.10 Td (e ) Tj ET Q q 0 0 0 rg BT 283.69 737.10 Td (perform ) Tj ET Q q 0 0 0 rg BT 317.50 737.10 Td (tests ) Tj ET Q q 0 0 0 rg BT 336.88 737.10 Td (at ) Tj ET Q q 0 0 0 rg BT 345.71 737.10 Td (various ) Tj ET Q q 0 0 0 rg BT 376.75 737.10 Td (stages ) Tj ET Q q 0 0 0 rg BT 402.80 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 412.73 737.10 Td (production ) Tj ET Q q 0 0 0 rg BT 457.67 737.10 Td (processes, ) Tj ET Q q 0 0 0 rg BT 500.09 737.10 Td (on ) Tj ET Q q 0 0 0 rg BT 511.70 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 525.52 737.10 Td (final ) Tj ET Q q 0 0 0 rg BT 545.45 737.10 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.83 725.10 Td (on ) Tj ET Q q 0 0 0 rg BT 65.22 725.10 Td (product ) Tj ET Q q 0 0 0 rg BT 98.16 725.10 Td (samples ) Tj ET Q q 0 0 0 rg BT 132.77 725.10 Td (held ) Tj ET Q q 0 0 0 rg BT 152.38 725.10 Td (on ) Tj ET Q q 0 0 0 rg BT 164.77 725.10 Td (stability ) Tj ET Q q 0 0 0 rg BT 199.38 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 209.55 725.10 Td (ensure ) Tj ET Q q 0 0 0 rg BT 238.04 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 255.43 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 270.04 725.10 Td (product ) Tj ET Q q 0 0 0 rg BT 302.98 725.10 Td (meets ) Tj ET Q q 0 0 0 rg BT 328.69 725.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 372.18 725.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 426.77 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 443.60 725.10 Td (conforms ) Tj ET Q q 0 0 0 rg BT 483.76 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 493.93 725.10 Td (our ) Tj ET Q q 0 0 0 rg BT 509.65 725.10 Td (standards. ) Tj ET Q q 0 0 0 rg BT 552.14 725.10 Td (These ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (tests ) Tj ET Q q 0 0 0 rg BT 56.35 713.10 Td (may ) Tj ET Q q 0 0 0 rg BT 76.13 713.10 Td (involve ) Tj ET Q q 0 0 0 rg BT 108.70 713.10 Td (chemical ) Tj ET Q q 0 0 0 rg BT 147.36 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 164.37 713.10 Td (physical ) Tj ET Q q 0 0 0 rg BT 200.26 713.10 Td (analyses, ) Tj ET Q q 0 0 0 rg BT 239.21 713.10 Td (microbiological ) Tj ET Q q 0 0 0 rg BT 305.09 713.10 Td (testing ) Tj ET Q q 0 0 0 rg BT 334.33 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 345.23 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 352.24 713.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 404.80 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 415.70 713.10 Td (these ) Tj ET Q q 0 0 0 rg BT 438.81 713.10 Td (along ) Tj ET Q q 0 0 0 rg BT 463.60 713.10 Td (with ) Tj ET Q q 0 0 0 rg BT 483.95 713.10 Td (other ) Tj ET Q q 0 0 0 rg BT 507.06 713.10 Td (analyses. ) Tj ET Q q 0 0 0 rg BT 546.01 713.10 Td (Quality ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (control ) Tj ET Q q 0 0 0 rg BT 66.83 701.10 Td (testing ) Tj ET Q q 0 0 0 rg BT 96.00 701.10 Td (is ) Tj ET Q q 0 0 0 rg BT 105.18 701.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 143.24 701.10 Td (by ) Tj ET Q q 0 0 0 rg BT 155.74 701.10 Td (business ) Tj ET Q q 0 0 0 rg BT 192.14 701.10 Td (unit/site ) Tj ET Q q 0 0 0 rg BT 226.87 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 243.82 701.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 289.09 701.10 Td (laboratories. ) Tj ET Q q 0 0 0 rg BT 341.30 701.10 Td (Quality ) Tj ET Q q 0 0 0 rg BT 373.80 701.10 Td (assurance ) Tj ET Q q 0 0 0 rg BT 415.17 701.10 Td (groups ) Tj ET Q q 0 0 0 rg BT 444.90 701.10 Td (routinely ) Tj ET Q q 0 0 0 rg BT 483.51 701.10 Td (monitor ) Tj ET Q q 0 0 0 rg BT 517.69 701.10 Td (manufacturing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 82.37 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 99.31 689.10 Td (systems ) Tj ET Q q 0 0 0 rg BT 133.48 689.10 Td (used ) Tj ET Q q 0 0 0 rg BT 154.31 689.10 Td (by ) Tj ET Q q 0 0 0 rg BT 166.81 689.10 Td (us, ) Tj ET Q q 0 0 0 rg BT 180.70 689.10 Td (our ) Tj ET Q q 0 0 0 rg BT 196.53 689.10 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 246.24 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 263.18 689.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 308.45 689.10 Td (suppliers ) Tj ET Q q 0 0 0 rg BT 347.05 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 357.33 689.10 Td (assure ) Tj ET Q q 0 0 0 rg BT 384.82 689.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 415.10 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 432.04 689.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 480.62 689.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 535.33 689.10 Td (are ) Tj ET Q q 0 0 0 rg BT 550.03 689.10 Td (met.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 666.30 Td (Envir) Tj ET Q q 0 0 0 rg BT 60.27 666.30 Td (onmental Regulation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 643.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.80 643.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 92.48 643.50 Td (and ) Tj ET Q q 0 0 0 rg BT 110.17 643.50 Td (operations ) Tj ET Q q 0 0 0 rg BT 155.07 643.50 Td (are ) Tj ET Q q 0 0 0 rg BT 170.53 643.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 202.10 643.50 Td (to ) Tj ET Q q 0 0 0 rg BT 213.13 643.50 Td (extensive ) Tj ET Q q 0 0 0 rg BT 254.14 643.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 275.18 643.50 Td (and ) Tj ET Q q 0 0 0 rg BT 292.87 643.50 Td (foreign ) Tj ET Q q 0 0 0 rg BT 324.99 643.50 Td (laws ) Tj ET Q q 0 0 0 rg BT 346.57 643.50 Td (and ) Tj ET Q q 0 0 0 rg BT 364.26 643.50 Td (regulations ) Tj ET Q q 0 0 0 rg BT 411.94 643.50 Td (relating ) Tj ET Q q 0 0 0 rg BT 445.73 643.50 Td (to ) Tj ET Q q 0 0 0 rg BT 456.76 643.50 Td (environmental ) Tj ET Q q 0 0 0 rg BT 517.77 643.50 Td (protection ) Tj ET Q q 0 0 0 rg BT 561.56 643.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 631.50 Td (human ) Tj ET Q q 0 0 0 rg BT 65.54 631.50 Td (health ) Tj ET Q q 0 0 0 rg BT 92.30 631.50 Td (and ) Tj ET Q q 0 0 0 rg BT 109.07 631.50 Td (safety) Tj ET Q q 0 0 0 rg BT 132.30 631.50 Td (, ) Tj ET Q q 0 0 0 rg BT 137.12 631.50 Td (including ) Tj ET Q q 0 0 0 rg BT 177.22 631.50 Td (those ) Tj ET Q q 0 0 0 rg BT 200.66 631.50 Td (governing ) Tj ET Q q 0 0 0 rg BT 243.53 631.50 Td (dischar) Tj ET Q q 0 0 0 rg BT 272.23 631.50 Td (ges ) Tj ET Q q 0 0 0 rg BT 287.88 631.50 Td (of ) Tj ET Q q 0 0 0 rg BT 298.54 631.50 Td (pollutants ) Tj ET Q q 0 0 0 rg BT 340.31 631.50 Td (into ) Tj ET Q q 0 0 0 rg BT 358.19 631.50 Td (the ) Tj ET Q q 0 0 0 rg BT 372.74 631.50 Td (air ) Tj ET Q q 0 0 0 rg BT 385.61 631.50 Td (and ) Tj ET Q q 0 0 0 rg BT 402.38 631.50 Td (water; ) Tj ET Q q 0 0 0 rg BT 429.69 631.50 Td (the ) Tj ET Q q 0 0 0 rg BT 444.23 631.50 Td (use, ) Tj ET Q q 0 0 0 rg BT 462.39 631.50 Td (management ) Tj ET Q q 0 0 0 rg BT 515.80 631.50 Td (and ) Tj ET Q q 0 0 0 rg BT 532.57 631.50 Td (disposal ) Tj ET Q q 0 0 0 rg BT 567.67 631.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 619.50 Td (hazardous, ) Tj ET Q q 0 0 0 rg BT 80.98 619.50 Td (radioactive ) Tj ET Q q 0 0 0 rg BT 127.33 619.50 Td (and ) Tj ET Q q 0 0 0 rg BT 143.71 619.50 Td (biological ) Tj ET Q q 0 0 0 rg BT 185.64 619.50 Td (materials ) Tj ET Q q 0 0 0 rg BT 224.23 619.50 Td (and ) Tj ET Q q 0 0 0 rg BT 240.60 619.50 Td (wastes; ) Tj ET Q q 0 0 0 rg BT 271.98 619.50 Td (and ) Tj ET Q q 0 0 0 rg BT 288.36 619.50 Td (the ) Tj ET Q q 0 0 0 rg BT 302.51 619.50 Td (cleanup ) Tj ET Q q 0 0 0 rg BT 335.55 619.50 Td (of ) Tj ET Q q 0 0 0 rg BT 345.81 619.50 Td (contamination. ) Tj ET Q q 0 0 0 rg BT 407.46 619.50 Td (Pollution ) Tj ET Q q 0 0 0 rg BT 446.07 619.50 Td (controls ) Tj ET Q q 0 0 0 rg BT 480.23 619.50 Td (and ) Tj ET Q q 0 0 0 rg BT 496.61 619.50 Td (permits ) Tj ET Q q 0 0 0 rg BT 528.54 619.50 Td (are ) Tj ET Q q 0 0 0 rg BT 542.68 619.50 Td (required ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 607.50 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 607.50 Td (many ) Tj ET Q q 0 0 0 rg BT 74.88 607.50 Td (of ) Tj ET Q q 0 0 0 rg BT 85.71 607.50 Td (our ) Tj ET Q q 0 0 0 rg BT 101.54 607.50 Td (operations, ) Tj ET Q q 0 0 0 rg BT 148.19 607.50 Td (and ) Tj ET Q q 0 0 0 rg BT 165.13 607.50 Td (these ) Tj ET Q q 0 0 0 rg BT 188.18 607.50 Td (permits ) Tj ET Q q 0 0 0 rg BT 220.67 607.50 Td (are ) Tj ET Q q 0 0 0 rg BT 235.38 607.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 266.21 607.50 Td (to ) Tj ET Q q 0 0 0 rg BT 276.48 607.50 Td (modification, ) Tj ET Q q 0 0 0 rg BT 332.58 607.50 Td (renewal ) Tj ET Q q 0 0 0 rg BT 366.73 607.50 Td (or ) Tj ET Q q 0 0 0 rg BT 377.56 607.50 Td (revocation ) Tj ET Q q 0 0 0 rg BT 422.26 607.50 Td (by ) Tj ET Q q 0 0 0 rg BT 434.76 607.50 Td (the ) Tj ET Q q 0 0 0 rg BT 449.48 607.50 Td (issuing ) Tj ET Q q 0 0 0 rg BT 480.32 607.50 Td (authorities.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 584.70 Td (Our ) Tj ET Q q 0 0 0 rg BT 55.29 584.70 Td (environment, ) Tj ET Q q 0 0 0 rg BT 112.08 584.70 Td (health ) Tj ET Q q 0 0 0 rg BT 140.25 584.70 Td (and ) Tj ET Q q 0 0 0 rg BT 158.43 584.70 Td (safety ) Tj ET Q q 0 0 0 rg BT 186.05 584.70 Td (group ) Tj ET Q q 0 0 0 rg BT 213.12 584.70 Td (monitors ) Tj ET Q q 0 0 0 rg BT 252.42 584.70 Td (our ) Tj ET Q q 0 0 0 rg BT 269.49 584.70 Td (operations ) Tj ET Q q 0 0 0 rg BT 314.89 584.70 Td (around ) Tj ET Q q 0 0 0 rg BT 346.40 584.70 Td (the ) Tj ET Q q 0 0 0 rg BT 362.36 584.70 Td (world, ) Tj ET Q q 0 0 0 rg BT 391.93 584.70 Td (providing ) Tj ET Q q 0 0 0 rg BT 434.56 584.70 Td (us ) Tj ET Q q 0 0 0 rg BT 447.19 584.70 Td (with ) Tj ET Q q 0 0 0 rg BT 468.71 584.70 Td (an ) Tj ET Q q 0 0 0 rg BT 481.89 584.70 Td (overview ) Tj ET Q q 0 0 0 rg BT 522.84 584.70 Td (of ) Tj ET Q q 0 0 0 rg BT 534.91 584.70 Td (regulatory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 572.70 Td (requirements ) Tj ET Q q 0 0 0 rg BT 91.37 572.70 Td (and ) Tj ET Q q 0 0 0 rg BT 108.98 572.70 Td (overseeing ) Tj ET Q q 0 0 0 rg BT 155.46 572.70 Td (the ) Tj ET Q q 0 0 0 rg BT 170.85 572.70 Td (implementation ) Tj ET Q q 0 0 0 rg BT 236.78 572.70 Td (of ) Tj ET Q q 0 0 0 rg BT 248.28 572.70 Td (our ) Tj ET Q q 0 0 0 rg BT 264.78 572.70 Td (standards ) Tj ET Q q 0 0 0 rg BT 305.72 572.70 Td (for ) Tj ET Q q 0 0 0 rg BT 320.55 572.70 Td (compliance. ) Tj ET Q q 0 0 0 rg BT 372.07 572.70 Td (W) Tj ET Q q 0 0 0 rg BT 380.71 572.70 Td (e ) Tj ET Q q 0 0 0 rg BT 388.32 572.70 Td (also ) Tj ET Q q 0 0 0 rg BT 407.60 572.70 Td (incur ) Tj ET Q q 0 0 0 rg BT 431.31 572.70 Td (operating ) Tj ET Q q 0 0 0 rg BT 472.25 572.70 Td (and ) Tj ET Q q 0 0 0 rg BT 489.85 572.70 Td (capital ) Tj ET Q q 0 0 0 rg BT 519.67 572.70 Td (costs ) Tj ET Q q 0 0 0 rg BT 542.84 572.70 Td (for ) Tj ET Q q 0 0 0 rg BT 557.67 572.70 Td (such ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 560.70 Td (matters ) Tj ET Q q 0 0 0 rg BT 67.79 560.70 Td (on ) Tj ET Q q 0 0 0 rg BT 80.15 560.70 Td (an ) Tj ET Q q 0 0 0 rg BT 91.94 560.70 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 127.07 560.70 Td (basis, ) Tj ET Q q 0 0 0 rg BT 151.93 560.70 Td (which ) Tj ET Q q 0 0 0 rg BT 178.72 560.70 Td (were ) Tj ET Q q 0 0 0 rg BT 200.51 560.70 Td (not ) Tj ET Q q 0 0 0 rg BT 215.64 560.70 Td (material ) Tj ET Q q 0 0 0 rg BT 250.76 560.70 Td (for ) Tj ET Q q 0 0 0 rg BT 264.77 560.70 Td (2017, ) Tj ET Q q 0 0 0 rg BT 289.63 560.70 Td (2016 ) Tj ET Q q 0 0 0 rg BT 311.99 560.70 Td (and ) Tj ET Q q 0 0 0 rg BT 328.78 560.70 Td (2015. ) Tj ET Q q 0 0 0 rg BT 353.64 560.70 Td (In ) Tj ET Q q 0 0 0 rg BT 364.32 560.70 Td (addition, ) Tj ET Q q 0 0 0 rg BT 401.95 560.70 Td (we ) Tj ET Q q 0 0 0 rg BT 415.97 560.70 Td (invested ) Tj ET Q q 0 0 0 rg BT 451.65 560.70 Td (in ) Tj ET Q q 0 0 0 rg BT 461.78 560.70 Td (projects ) Tj ET Q q 0 0 0 rg BT 495.79 560.70 Td (that ) Tj ET Q q 0 0 0 rg BT 513.15 560.70 Td (reduce ) Tj ET Q q 0 0 0 rg BT 542.15 560.70 Td (resource ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 548.70 Td (use ) Tj ET Q q 0 0 0 rg BT 52.37 548.70 Td (of ) Tj ET Q q 0 0 0 rg BT 63.73 548.70 Td (ener) Tj ET Q q 0 0 0 rg BT 80.76 548.70 Td (gy ) Tj ET Q q 0 0 0 rg BT 93.80 548.70 Td (and ) Tj ET Q q 0 0 0 rg BT 111.27 548.70 Td (water) Tj ET Q q 0 0 0 rg BT 132.93 548.70 Td (. ) Tj ET Q q 0 0 0 rg BT 137.80 548.70 Td (Although ) Tj ET Q q 0 0 0 rg BT 178.61 548.70 Td (we ) Tj ET Q q 0 0 0 rg BT 193.31 548.70 Td (believe ) Tj ET Q q 0 0 0 rg BT 225.22 548.70 Td (that ) Tj ET Q q 0 0 0 rg BT 243.25 548.70 Td (we ) Tj ET Q q 0 0 0 rg BT 257.95 548.70 Td (are ) Tj ET Q q 0 0 0 rg BT 273.19 548.70 Td (in ) Tj ET Q q 0 0 0 rg BT 284.01 548.70 Td (substantial ) Tj ET Q q 0 0 0 rg BT 329.82 548.70 Td (compliance ) Tj ET Q q 0 0 0 rg BT 378.94 548.70 Td (with ) Tj ET Q q 0 0 0 rg BT 399.76 548.70 Td (applicable ) Tj ET Q q 0 0 0 rg BT 443.88 548.70 Td (environmental, ) Tj ET Q q 0 0 0 rg BT 507.18 548.70 Td (health ) Tj ET Q q 0 0 0 rg BT 534.65 548.70 Td (and ) Tj ET Q q 0 0 0 rg BT 552.13 548.70 Td (safety ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 536.70 Td (requirements ) Tj ET Q q 0 0 0 rg BT 90.74 536.70 Td (and ) Tj ET Q q 0 0 0 rg BT 107.72 536.70 Td (the ) Tj ET Q q 0 0 0 rg BT 122.48 536.70 Td (permits ) Tj ET Q q 0 0 0 rg BT 155.01 536.70 Td (required ) Tj ET Q q 0 0 0 rg BT 190.87 536.70 Td (for ) Tj ET Q q 0 0 0 rg BT 205.07 536.70 Td (our ) Tj ET Q q 0 0 0 rg BT 220.94 536.70 Td (operations, ) Tj ET Q q 0 0 0 rg BT 267.64 536.70 Td (we ) Tj ET Q q 0 0 0 rg BT 281.84 536.70 Td (nevertheless ) Tj ET Q q 0 0 0 rg BT 333.80 536.70 Td (could ) Tj ET Q q 0 0 0 rg BT 358.56 536.70 Td (incur ) Tj ET Q q 0 0 0 rg BT 381.65 536.70 Td (additional ) Tj ET Q q 0 0 0 rg BT 424.18 536.70 Td (costs, ) Tj ET Q q 0 0 0 rg BT 449.22 536.70 Td (including ) Tj ET Q q 0 0 0 rg BT 489.53 536.70 Td (civil ) Tj ET Q q 0 0 0 rg BT 509.85 536.70 Td (or ) Tj ET Q q 0 0 0 rg BT 520.72 536.70 Td (criminal ) Tj ET Q q 0 0 0 rg BT 556.58 536.70 Td (fines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 524.70 Td (or ) Tj ET Q q 0 0 0 rg BT 46.83 524.70 Td (penalties, ) Tj ET Q q 0 0 0 rg BT 87.37 524.70 Td (clean-up ) Tj ET Q q 0 0 0 rg BT 124.30 524.70 Td (costs ) Tj ET Q q 0 0 0 rg BT 146.80 524.70 Td (or ) Tj ET Q q 0 0 0 rg BT 157.63 524.70 Td (third-party ) Tj ET Q q 0 0 0 rg BT 202.89 524.70 Td (claims ) Tj ET Q q 0 0 0 rg BT 231.49 524.70 Td (for ) Tj ET Q q 0 0 0 rg BT 245.65 524.70 Td (property ) Tj ET Q q 0 0 0 rg BT 282.03 524.70 Td (damage ) Tj ET Q q 0 0 0 rg BT 315.62 524.70 Td (or ) Tj ET Q q 0 0 0 rg BT 326.45 524.70 Td (personal ) Tj ET Q q 0 0 0 rg BT 362.83 524.70 Td (injury) Tj ET Q q 0 0 0 rg BT 386.07 524.70 Td (, ) Tj ET Q q 0 0 0 rg BT 391.07 524.70 Td (for ) Tj ET Q q 0 0 0 rg BT 405.23 524.70 Td (violations ) Tj ET Q q 0 0 0 rg BT 447.17 524.70 Td (or ) Tj ET Q q 0 0 0 rg BT 458.00 524.70 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 497.72 524.70 Td (under ) Tj ET Q q 0 0 0 rg BT 522.99 524.70 Td (these ) Tj ET Q q 0 0 0 rg BT 546.03 524.70 Td (laws.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 501.90 Td (Many ) Tj ET Q q 0 0 0 rg BT 61.49 501.90 Td (of ) Tj ET Q q 0 0 0 rg BT 71.98 501.90 Td (our ) Tj ET Q q 0 0 0 rg BT 87.47 501.90 Td (current ) Tj ET Q q 0 0 0 rg BT 117.94 501.90 Td (and ) Tj ET Q q 0 0 0 rg BT 134.54 501.90 Td (former ) Tj ET Q q 0 0 0 rg BT 163.91 501.90 Td (facilities ) Tj ET Q q 0 0 0 rg BT 200.50 501.90 Td (have ) Tj ET Q q 0 0 0 rg BT 221.53 501.90 Td (been ) Tj ET Q q 0 0 0 rg BT 242.57 501.90 Td (in ) Tj ET Q q 0 0 0 rg BT 252.51 501.90 Td (operation ) Tj ET Q q 0 0 0 rg BT 292.43 501.90 Td (for ) Tj ET Q q 0 0 0 rg BT 306.25 501.90 Td (many ) Tj ET Q q 0 0 0 rg BT 330.63 501.90 Td (years, ) Tj ET Q q 0 0 0 rg BT 356.39 501.90 Td (and ) Tj ET Q q 0 0 0 rg BT 372.98 501.90 Td (over ) Tj ET Q q 0 0 0 rg BT 392.91 501.90 Td (time, ) Tj ET Q q 0 0 0 rg BT 415.35 501.90 Td (we ) Tj ET Q q 0 0 0 rg BT 429.17 501.90 Td (and ) Tj ET Q q 0 0 0 rg BT 445.76 501.90 Td (other ) Tj ET Q q 0 0 0 rg BT 468.47 501.90 Td (operators ) Tj ET Q q 0 0 0 rg BT 507.84 501.90 Td (of ) Tj ET Q q 0 0 0 rg BT 518.33 501.90 Td (those ) Tj ET Q q 0 0 0 rg BT 541.60 501.90 Td (facilities ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 489.90 Td (have ) Tj ET Q q 0 0 0 rg BT 58.55 489.90 Td (generated, ) Tj ET Q q 0 0 0 rg BT 103.58 489.90 Td (used, ) Tj ET Q q 0 0 0 rg BT 128.07 489.90 Td (stored ) Tj ET Q q 0 0 0 rg BT 156.18 489.90 Td (or ) Tj ET Q q 0 0 0 rg BT 168.18 489.90 Td (disposed ) Tj ET Q q 0 0 0 rg BT 206.85 489.90 Td (of ) Tj ET Q q 0 0 0 rg BT 218.85 489.90 Td (substances ) Tj ET Q q 0 0 0 rg BT 265.28 489.90 Td (or ) Tj ET Q q 0 0 0 rg BT 277.28 489.90 Td (wastes ) Tj ET Q q 0 0 0 rg BT 307.61 489.90 Td (that ) Tj ET Q q 0 0 0 rg BT 326.27 489.90 Td (are ) Tj ET Q q 0 0 0 rg BT 342.15 489.90 Td (considered ) Tj ET Q q 0 0 0 rg BT 389.13 489.90 Td (hazardous ) Tj ET Q q 0 0 0 rg BT 433.34 489.90 Td (under ) Tj ET Q q 0 0 0 rg BT 459.78 489.90 Td (Federal, ) Tj ET Q q 0 0 0 rg BT 495.93 489.90 Td (state ) Tj ET Q q 0 0 0 rg BT 517.92 489.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 547.14 489.90 Td (foreign ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 477.90 Td (environmental ) Tj ET Q q 0 0 0 rg BT 97.58 477.90 Td (laws, ) Tj ET Q q 0 0 0 rg BT 122.22 477.90 Td (including ) Tj ET Q q 0 0 0 rg BT 163.81 477.90 Td (CERCLA. ) Tj ET Q q 0 0 0 rg BT 208.73 477.90 Td (As ) Tj ET Q q 0 0 0 rg BT 223.66 477.90 Td (a ) Tj ET Q q 0 0 0 rg BT 231.92 477.90 Td (result, ) Tj ET Q q 0 0 0 rg BT 260.45 477.90 Td (the ) Tj ET Q q 0 0 0 rg BT 276.48 477.90 Td (soil ) Tj ET Q q 0 0 0 rg BT 294.75 477.90 Td (and ) Tj ET Q q 0 0 0 rg BT 313.00 477.90 Td (groundwater ) Tj ET Q q 0 0 0 rg BT 367.36 477.90 Td (at ) Tj ET Q q 0 0 0 rg BT 378.39 477.90 Td (or ) Tj ET Q q 0 0 0 rg BT 390.54 477.90 Td (under ) Tj ET Q q 0 0 0 rg BT 417.12 477.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 448.14 477.90 Td (of ) Tj ET Q q 0 0 0 rg BT 460.29 477.90 Td (these ) Tj ET Q q 0 0 0 rg BT 484.65 477.90 Td (facilities ) Tj ET Q q 0 0 0 rg BT 522.90 477.90 Td (is ) Tj ET Q q 0 0 0 rg BT 533.38 477.90 Td (or ) Tj ET Q q 0 0 0 rg BT 545.53 477.90 Td (may ) Tj ET Q q 0 0 0 rg BT 566.56 477.90 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 465.90 Td (contaminated, ) Tj ET Q q 0 0 0 rg BT 95.11 465.90 Td (and ) Tj ET Q q 0 0 0 rg BT 112.28 465.90 Td (we ) Tj ET Q q 0 0 0 rg BT 126.68 465.90 Td (may ) Tj ET Q q 0 0 0 rg BT 146.64 465.90 Td (be ) Tj ET Q q 0 0 0 rg BT 158.82 465.90 Td (required ) Tj ET Q q 0 0 0 rg BT 194.87 465.90 Td (to ) Tj ET Q q 0 0 0 rg BT 205.39 465.90 Td (make ) Tj ET Q q 0 0 0 rg BT 229.78 465.90 Td (significant ) Tj ET Q q 0 0 0 rg BT 274.74 465.90 Td (expenditures ) Tj ET Q q 0 0 0 rg BT 328.57 465.90 Td (to ) Tj ET Q q 0 0 0 rg BT 339.09 465.90 Td (investigate, ) Tj ET Q q 0 0 0 rg BT 387.65 465.90 Td (control ) Tj ET Q q 0 0 0 rg BT 418.71 465.90 Td (and ) Tj ET Q q 0 0 0 rg BT 435.89 465.90 Td (remediate ) Tj ET Q q 0 0 0 rg BT 478.05 465.90 Td (such ) Tj ET Q q 0 0 0 rg BT 499.12 465.90 Td (contamination, ) Tj ET Q q 0 0 0 rg BT 561.56 465.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.90 Td (in ) Tj ET Q q 0 0 0 rg BT 46.38 453.90 Td (some ) Tj ET Q q 0 0 0 rg BT 70.10 453.90 Td (cases ) Tj ET Q q 0 0 0 rg BT 93.80 453.90 Td (to ) Tj ET Q q 0 0 0 rg BT 104.19 453.90 Td (provide ) Tj ET Q q 0 0 0 rg BT 137.34 453.90 Td (compensation ) Tj ET Q q 0 0 0 rg BT 195.49 453.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 223.64 453.90 Td (restoration ) Tj ET Q q 0 0 0 rg BT 269.01 453.90 Td (for ) Tj ET Q q 0 0 0 rg BT 283.28 453.90 Td (damages ) Tj ET Q q 0 0 0 rg BT 320.87 453.90 Td (to ) Tj ET Q q 0 0 0 rg BT 331.26 453.90 Td (natural ) Tj ET Q q 0 0 0 rg BT 361.63 453.90 Td (resources. ) Tj ET Q q 0 0 0 rg BT 404.49 453.90 Td (Currently) Tj ET Q q 0 0 0 rg BT 442.17 453.90 Td (, ) Tj ET Q q 0 0 0 rg BT 447.28 453.90 Td (we ) Tj ET Q q 0 0 0 rg BT 461.54 453.90 Td (are ) Tj ET Q q 0 0 0 rg BT 476.36 453.90 Td (involved ) Tj ET Q q 0 0 0 rg BT 513.96 453.90 Td (in ) Tj ET Q q 0 0 0 rg BT 524.34 453.90 Td (investigation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.90 Td (and ) Tj ET Q q 0 0 0 rg BT 51.92 441.90 Td (remediation ) Tj ET Q q 0 0 0 rg BT 101.17 441.90 Td (at ) Tj ET Q q 0 0 0 rg BT 109.87 441.90 Td (16 ) Tj ET Q q 0 0 0 rg BT 121.36 441.90 Td (current ) Tj ET Q q 0 0 0 rg BT 151.16 441.90 Td (or ) Tj ET Q q 0 0 0 rg BT 160.97 441.90 Td (former ) Tj ET Q q 0 0 0 rg BT 189.67 441.90 Td (facilities. ) Tj ET Q q 0 0 0 rg BT 227.97 441.90 Td (W) Tj ET Q q 0 0 0 rg BT 236.61 441.90 Td (e ) Tj ET Q q 0 0 0 rg BT 242.54 441.90 Td (have ) Tj ET Q q 0 0 0 rg BT 262.90 441.90 Td (also ) Tj ET Q q 0 0 0 rg BT 280.49 441.90 Td (been ) Tj ET Q q 0 0 0 rg BT 300.86 441.90 Td (identified ) Tj ET Q q 0 0 0 rg BT 340.66 441.90 Td (as ) Tj ET Q q 0 0 0 rg BT 350.48 441.90 Td (a ) Tj ET Q q 0 0 0 rg BT 356.40 441.90 Td (PRP) Tj ET Q q 0 0 0 rg BT 373.82 441.90 Td ( ) Tj ET Q q 0 0 0 rg BT 375.31 441.90 Td (under ) Tj ET Q q 0 0 0 rg BT 399.56 441.90 Td (applicable ) Tj ET Q q 0 0 0 rg BT 442.14 441.90 Td (laws ) Tj ET Q q 0 0 0 rg BT 461.96 441.90 Td (for ) Tj ET Q q 0 0 0 rg BT 475.10 441.90 Td (environmental ) Tj ET Q q 0 0 0 rg BT 534.35 441.90 Td (conditions ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 429.90 Td (at ) Tj ET Q q 0 0 0 rg BT 45.71 429.90 Td (approximately ) Tj ET Q q 0 0 0 rg BT 105.96 429.90 Td (20 ) Tj ET Q q 0 0 0 rg BT 118.46 429.90 Td (former ) Tj ET Q q 0 0 0 rg BT 148.16 429.90 Td (waste ) Tj ET Q q 0 0 0 rg BT 173.42 429.90 Td (disposal ) Tj ET Q q 0 0 0 rg BT 208.69 429.90 Td (or ) Tj ET Q q 0 0 0 rg BT 219.52 429.90 Td (reprocessing ) Tj ET Q q 0 0 0 rg BT 272.55 429.90 Td (facilities ) Tj ET Q q 0 0 0 rg BT 309.47 429.90 Td (operated ) Tj ET Q q 0 0 0 rg BT 346.39 429.90 Td (by ) Tj ET Q q 0 0 0 rg BT 358.88 429.90 Td (third ) Tj ET Q q 0 0 0 rg BT 380.27 429.90 Td (parties ) Tj ET Q q 0 0 0 rg BT 409.42 429.90 Td (at ) Tj ET Q q 0 0 0 rg BT 419.13 429.90 Td (which ) Tj ET Q q 0 0 0 rg BT 446.06 429.90 Td (investigation ) Tj ET Q q 0 0 0 rg BT 500.21 429.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 528.25 429.90 Td (remediation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 417.90 Td (activities ) Tj ET Q q 0 0 0 rg BT 74.60 417.90 Td (are ) Tj ET Q q 0 0 0 rg BT 89.31 417.90 Td (ongoing.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 395.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 395.10 Td (e ) Tj ET Q q 0 0 0 rg BT 52.21 395.10 Td (may ) Tj ET Q q 0 0 0 rg BT 72.55 395.10 Td (face ) Tj ET Q q 0 0 0 rg BT 92.33 395.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 126.56 395.10 Td (under ) Tj ET Q q 0 0 0 rg BT 152.46 395.10 Td (CERCLA) Tj ET Q q 0 0 0 rg BT 191.36 395.10 Td ( ) Tj ET Q q 0 0 0 rg BT 194.49 395.10 Td (and ) Tj ET Q q 0 0 0 rg BT 212.05 395.10 Td (other ) Tj ET Q q 0 0 0 rg BT 235.73 395.10 Td (Federal, ) Tj ET Q q 0 0 0 rg BT 271.34 395.10 Td (state ) Tj ET Q q 0 0 0 rg BT 292.80 395.10 Td (and ) Tj ET Q q 0 0 0 rg BT 310.36 395.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 342.37 395.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 363.83 395.10 Td (for ) Tj ET Q q 0 0 0 rg BT 378.62 395.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.96 395.10 Td (entire ) Tj ET Q q 0 0 0 rg BT 419.86 395.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 439.09 395.10 Td (of ) Tj ET Q q 0 0 0 rg BT 450.55 395.10 Td (investigation ) Tj ET Q q 0 0 0 rg BT 505.34 395.10 Td (or ) Tj ET Q q 0 0 0 rg BT 516.80 395.10 Td (remediation ) Tj ET Q q 0 0 0 rg BT 567.69 395.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 383.10 Td (contaminated ) Tj ET Q q 0 0 0 rg BT 92.57 383.10 Td (sites, ) Tj ET Q q 0 0 0 rg BT 115.56 383.10 Td (or ) Tj ET Q q 0 0 0 rg BT 126.60 383.10 Td (for ) Tj ET Q q 0 0 0 rg BT 140.97 383.10 Td (natural ) Tj ET Q q 0 0 0 rg BT 171.44 383.10 Td (resource ) Tj ET Q q 0 0 0 rg BT 208.01 383.10 Td (damages, ) Tj ET Q q 0 0 0 rg BT 248.20 383.10 Td (regardless ) Tj ET Q q 0 0 0 rg BT 291.45 383.10 Td (of ) Tj ET Q q 0 0 0 rg BT 302.49 383.10 Td (fault ) Tj ET Q q 0 0 0 rg BT 323.52 383.10 Td (or ) Tj ET Q q 0 0 0 rg BT 334.56 383.10 Td (ownership ) Tj ET Q q 0 0 0 rg BT 378.92 383.10 Td (at ) Tj ET Q q 0 0 0 rg BT 388.85 383.10 Td (the ) Tj ET Q q 0 0 0 rg BT 403.77 383.10 Td (time ) Tj ET Q q 0 0 0 rg BT 424.25 383.10 Td (of ) Tj ET Q q 0 0 0 rg BT 435.29 383.10 Td (the ) Tj ET Q q 0 0 0 rg BT 450.22 383.10 Td (disposal ) Tj ET Q q 0 0 0 rg BT 485.70 383.10 Td (or ) Tj ET Q q 0 0 0 rg BT 496.74 383.10 Td (release. ) Tj ET Q q 0 0 0 rg BT 529.70 383.10 Td (In ) Tj ET Q q 0 0 0 rg BT 540.74 383.10 Td (addition, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 371.10 Td (at ) Tj ET Q q 0 0 0 rg BT 45.87 371.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 75.73 371.10 Td (sites ) Tj ET Q q 0 0 0 rg BT 96.16 371.10 Td (we ) Tj ET Q q 0 0 0 rg BT 110.48 371.10 Td (bear ) Tj ET Q q 0 0 0 rg BT 130.34 371.10 Td (remediation ) Tj ET Q q 0 0 0 rg BT 180.75 371.10 Td (responsibility ) Tj ET Q q 0 0 0 rg BT 237.85 371.10 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 274.95 371.10 Td (to ) Tj ET Q q 0 0 0 rg BT 285.38 371.10 Td (contractual ) Tj ET Q q 0 0 0 rg BT 332.46 371.10 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 382.05 371.10 Td (Generally) Tj ET Q q 0 0 0 rg BT 420.83 371.10 Td (, ) Tj ET Q q 0 0 0 rg BT 425.98 371.10 Td (at ) Tj ET Q q 0 0 0 rg BT 435.86 371.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 481.27 371.10 Td (operator ) Tj ET Q q 0 0 0 rg BT 517.25 371.10 Td (sites ) Tj ET Q q 0 0 0 rg BT 537.68 371.10 Td (involving ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 359.10 Td (multiple ) Tj ET Q q 0 0 0 rg BT 71.92 359.10 Td (PRPs, ) Tj ET Q q 0 0 0 rg BT 98.69 359.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 132.38 359.10 Td (has ) Tj ET Q q 0 0 0 rg BT 148.29 359.10 Td (been ) Tj ET Q q 0 0 0 rg BT 169.76 359.10 Td (or ) Tj ET Q q 0 0 0 rg BT 180.67 359.10 Td (is ) Tj ET Q q 0 0 0 rg BT 189.93 359.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 228.05 359.10 Td (to ) Tj ET Q q 0 0 0 rg BT 238.41 359.10 Td (be ) Tj ET Q q 0 0 0 rg BT 250.43 359.10 Td (apportioned ) Tj ET Q q 0 0 0 rg BT 300.78 359.10 Td (based ) Tj ET Q q 0 0 0 rg BT 326.14 359.10 Td (on ) Tj ET Q q 0 0 0 rg BT 338.72 359.10 Td (the ) Tj ET Q q 0 0 0 rg BT 353.52 359.10 Td (nature ) Tj ET Q q 0 0 0 rg BT 381.10 359.10 Td (and ) Tj ET Q q 0 0 0 rg BT 398.12 359.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 430.70 359.10 Td (of ) Tj ET Q q 0 0 0 rg BT 441.62 359.10 Td (hazardous ) Tj ET Q q 0 0 0 rg BT 484.74 359.10 Td (substances ) Tj ET Q q 0 0 0 rg BT 530.09 359.10 Td (disposed ) Tj ET Q q 0 0 0 rg BT 567.68 359.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 347.10 Td (by ) Tj ET Q q 0 0 0 rg BT 49.10 347.10 Td (each ) Tj ET Q q 0 0 0 rg BT 70.52 347.10 Td (party ) Tj ET Q q 0 0 0 rg BT 94.16 347.10 Td (at ) Tj ET Q q 0 0 0 rg BT 104.48 347.10 Td (the ) Tj ET Q q 0 0 0 rg BT 119.80 347.10 Td (site ) Tj ET Q q 0 0 0 rg BT 136.79 347.10 Td (and ) Tj ET Q q 0 0 0 rg BT 154.33 347.10 Td (the ) Tj ET Q q 0 0 0 rg BT 169.64 347.10 Td (number ) Tj ET Q q 0 0 0 rg BT 203.29 347.10 Td (of ) Tj ET Q q 0 0 0 rg BT 214.72 347.10 Td (financially ) Tj ET Q q 0 0 0 rg BT 260.58 347.10 Td (viable ) Tj ET Q q 0 0 0 rg BT 288.11 347.10 Td (PRPs. ) Tj ET Q q 0 0 0 rg BT 315.40 347.10 Td (For ) Tj ET Q q 0 0 0 rg BT 332.39 347.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 375.48 347.10 Td (information ) Tj ET Q q 0 0 0 rg BT 425.79 347.10 Td (about ) Tj ET Q q 0 0 0 rg BT 451.11 347.10 Td (these ) Tj ET Q q 0 0 0 rg BT 474.76 347.10 Td (matters, ) Tj ET Q q 0 0 0 rg BT 509.79 347.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 531.76 347.10 Td (to ) Tj ET Q q 0 0 0 rg BT 542.64 347.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 568.50 347.10 Td (8. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 335.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 75.71 335.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 151.53 335.10 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 161.53 335.10 Td (. ) Tj ET Q q 0 0 0 rg BT 166.53 335.10 Td (Legal ) Tj ET Q q 0 0 0 rg BT 191.80 335.10 Td (Proceedings ) Tj ET Q q 0 0 0 rg BT 243.17 335.10 Td (and ) Tj ET Q q 0 0 0 rg BT 260.11 335.10 Td (Contingencies.”) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 312.30 Td (Employees) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 289.50 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 289.50 Td (e ) Tj ET Q q 0 0 0 rg BT 51.58 289.50 Td (have ) Tj ET Q q 0 0 0 rg BT 72.95 289.50 Td (approximately ) Tj ET Q q 0 0 0 rg BT 133.21 289.50 Td (23,700 ) Tj ET Q q 0 0 0 rg BT 163.21 289.50 Td (employees ) Tj ET Q q 0 0 0 rg BT 208.48 289.50 Td (as ) Tj ET Q q 0 0 0 rg BT 219.31 289.50 Td (of ) Tj ET Q q 0 0 0 rg BT 230.14 289.50 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.72 289.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 308.72 289.50 Td (. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 265.50 Td (For) Tj ET Q q 0 0 0 rg BT 51.37 265.50 Td (eign Operations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.50 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 241.50 Td (e ) Tj ET Q q 0 0 0 rg BT 51.58 241.50 Td (have ) Tj ET Q q 0 0 0 rg BT 72.95 241.50 Td (significant ) Tj ET Q q 0 0 0 rg BT 117.67 241.50 Td (operations ) Tj ET Q q 0 0 0 rg BT 161.82 241.50 Td (outside ) Tj ET Q q 0 0 0 rg BT 193.21 241.50 Td (the ) Tj ET Q q 0 0 0 rg BT 207.92 241.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 228.03 241.50 Td (They ) Tj ET Q q 0 0 0 rg BT 251.07 241.50 Td (are ) Tj ET Q q 0 0 0 rg BT 265.78 241.50 Td (conducted ) Tj ET Q q 0 0 0 rg BT 309.37 241.50 Td (both ) Tj ET Q q 0 0 0 rg BT 329.65 241.50 Td (through ) Tj ET Q q 0 0 0 rg BT 363.26 241.50 Td (our ) Tj ET Q q 0 0 0 rg BT 379.09 241.50 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 428.81 241.50 Td (and ) Tj ET Q q 0 0 0 rg BT 445.75 241.50 Td (through ) Tj ET Q q 0 0 0 rg BT 479.35 241.50 Td (distributors.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.50 Td (International ) Tj ET Q q 0 0 0 rg BT 90.46 217.50 Td (operations ) Tj ET Q q 0 0 0 rg BT 135.49 217.50 Td (are ) Tj ET Q q 0 0 0 rg BT 151.07 217.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 182.76 217.50 Td (to ) Tj ET Q q 0 0 0 rg BT 193.91 217.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 224.49 217.50 Td (risks, ) Tj ET Q q 0 0 0 rg BT 249.25 217.50 Td (which ) Tj ET Q q 0 0 0 rg BT 277.06 217.50 Td (are ) Tj ET Q q 0 0 0 rg BT 292.64 217.50 Td (inherent ) Tj ET Q q 0 0 0 rg BT 328.77 217.50 Td (in ) Tj ET Q q 0 0 0 rg BT 339.92 217.50 Td (conducting ) Tj ET Q q 0 0 0 rg BT 387.73 217.50 Td (business ) Tj ET Q q 0 0 0 rg BT 424.99 217.50 Td (abroad, ) Tj ET Q q 0 0 0 rg BT 458.07 217.50 Td (including, ) Tj ET Q q 0 0 0 rg BT 501.72 217.50 Td (but ) Tj ET Q q 0 0 0 rg BT 517.87 217.50 Td (not ) Tj ET Q q 0 0 0 rg BT 534.02 217.50 Td (limited ) Tj ET Q q 0 0 0 rg BT 565.72 217.50 Td (to, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 205.50 Td (currency ) Tj ET Q q 0 0 0 rg BT 73.09 205.50 Td (fluctuations, ) Tj ET Q q 0 0 0 rg BT 124.92 205.50 Td (possible ) Tj ET Q q 0 0 0 rg BT 159.81 205.50 Td (nationalization ) Tj ET Q q 0 0 0 rg BT 221.35 205.50 Td (or ) Tj ET Q q 0 0 0 rg BT 231.80 205.50 Td (expropriation, ) Tj ET Q q 0 0 0 rg BT 290.29 205.50 Td (price ) Tj ET Q q 0 0 0 rg BT 312.39 205.50 Td (and ) Tj ET Q q 0 0 0 rg BT 328.94 205.50 Td (exchange ) Tj ET Q q 0 0 0 rg BT 368.81 205.50 Td (controls, ) Tj ET Q q 0 0 0 rg BT 405.64 205.50 Td (counterfeit ) Tj ET Q q 0 0 0 rg BT 451.07 205.50 Td (products, ) Tj ET Q q 0 0 0 rg BT 490.12 205.50 Td (limitations ) Tj ET Q q 0 0 0 rg BT 535.02 205.50 Td (on ) Tj ET Q q 0 0 0 rg BT 547.13 205.50 Td (foreign ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 193.50 Td (participation ) Tj ET Q q 0 0 0 rg BT 88.68 193.50 Td (in ) Tj ET Q q 0 0 0 rg BT 98.61 193.50 Td (local ) Tj ET Q q 0 0 0 rg BT 120.19 193.50 Td (enterprises ) Tj ET Q q 0 0 0 rg BT 165.65 193.50 Td (and ) Tj ET Q q 0 0 0 rg BT 182.23 193.50 Td (other ) Tj ET Q q 0 0 0 rg BT 204.93 193.50 Td (restrictive ) Tj ET Q q 0 0 0 rg BT 247.05 193.50 Td (governmental ) Tj ET Q q 0 0 0 rg BT 304.18 193.50 Td (actions. ) Tj ET Q q 0 0 0 rg BT 337.15 193.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 354.85 193.50 Td (international ) Tj ET Q q 0 0 0 rg BT 407.53 193.50 Td (businesses ) Tj ET Q q 0 0 0 rg BT 451.90 193.50 Td (are ) Tj ET Q q 0 0 0 rg BT 466.25 193.50 Td (also ) Tj ET Q q 0 0 0 rg BT 484.51 193.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 514.98 193.50 Td (to ) Tj ET Q q 0 0 0 rg BT 524.90 193.50 Td (government-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.50 Td (imposed ) Tj ET Q q 0 0 0 rg BT 72.39 181.50 Td (constraints, ) Tj ET Q q 0 0 0 rg BT 120.71 181.50 Td (including ) Tj ET Q q 0 0 0 rg BT 160.99 181.50 Td (laws ) Tj ET Q q 0 0 0 rg BT 181.82 181.50 Td (on ) Tj ET Q q 0 0 0 rg BT 194.32 181.50 Td (pricing ) Tj ET Q q 0 0 0 rg BT 225.14 181.50 Td (or ) Tj ET Q q 0 0 0 rg BT 235.97 181.50 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 298.45 181.50 Td (for ) Tj ET Q q 0 0 0 rg BT 312.61 181.50 Td (use ) Tj ET Q q 0 0 0 rg BT 328.44 181.50 Td (of ) Tj ET Q q 0 0 0 rg BT 339.27 181.50 Td (products.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 157.50 Td (Bristol-Myers Squibb ) Tj ET Q q 0 0 0 rg BT 130.83 157.50 Td (W) Tj ET Q q 0 0 0 rg BT 140.28 157.50 Td (ebsite) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 133.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.69 133.50 Td (internet ) Tj ET Q q 0 0 0 rg BT 88.37 133.50 Td (website ) Tj ET Q q 0 0 0 rg BT 122.06 133.50 Td (address ) Tj ET Q q 0 0 0 rg BT 155.19 133.50 Td (is ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 164.994140625 132.1669921875 m 224.896484375 132.1669921875 l s q 0 0 0 rg BT 164.99 133.50 Td (www) Tj ET Q q 0 0 0 rg BT 186.01 133.50 Td (.bms.com) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 224.90 133.50 Td (. ) Tj ET Q q 0 0 0 rg BT 230.54 133.50 Td (On ) Tj ET Q q 0 0 0 rg BT 245.90 133.50 Td (our ) Tj ET Q q 0 0 0 rg BT 262.36 133.50 Td (website, ) Tj ET Q q 0 0 0 rg BT 298.55 133.50 Td (we ) Tj ET Q q 0 0 0 rg BT 313.35 133.50 Td (make ) Tj ET Q q 0 0 0 rg BT 338.14 133.50 Td (available, ) Tj ET Q q 0 0 0 rg BT 379.87 133.50 Td (free ) Tj ET Q q 0 0 0 rg BT 398.55 133.50 Td (of ) Tj ET Q q 0 0 0 rg BT 410.01 133.50 Td (char) Tj ET Q q 0 0 0 rg BT 427.04 133.50 Td (ge, ) Tj ET Q q 0 0 0 rg BT 442.12 133.50 Td (our ) Tj ET Q q 0 0 0 rg BT 458.59 133.50 Td (annual, ) Tj ET Q q 0 0 0 rg BT 490.88 133.50 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 530.11 133.50 Td (and ) Tj ET Q q 0 0 0 rg BT 547.69 133.50 Td (current ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 121.50 Td (reports, ) Tj ET Q q 0 0 0 rg BT 68.19 121.50 Td (including ) Tj ET Q q 0 0 0 rg BT 107.89 121.50 Td (amendments ) Tj ET Q q 0 0 0 rg BT 160.36 121.50 Td (to ) Tj ET Q q 0 0 0 rg BT 170.06 121.50 Td (such ) Tj ET Q q 0 0 0 rg BT 190.32 121.50 Td (reports, ) Tj ET Q q 0 0 0 rg BT 222.51 121.50 Td (as ) Tj ET Q q 0 0 0 rg BT 232.77 121.50 Td (soon ) Tj ET Q q 0 0 0 rg BT 253.58 121.50 Td (as ) Tj ET Q q 0 0 0 rg BT 263.84 121.50 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 309.08 121.50 Td (practicable ) Tj ET Q q 0 0 0 rg BT 354.86 121.50 Td (after ) Tj ET Q q 0 0 0 rg BT 375.10 121.50 Td (we ) Tj ET Q q 0 0 0 rg BT 388.69 121.50 Td (electronically ) Tj ET Q q 0 0 0 rg BT 445.03 121.50 Td (file ) Tj ET Q q 0 0 0 rg BT 460.28 121.50 Td (such ) Tj ET Q q 0 0 0 rg BT 480.54 121.50 Td (material ) Tj ET Q q 0 0 0 rg BT 515.22 121.50 Td (with, ) Tj ET Q q 0 0 0 rg BT 537.42 121.50 Td (or ) Tj ET Q q 0 0 0 rg BT 547.68 121.50 Td (furnish ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 109.50 Td (such ) Tj ET Q q 0 0 0 rg BT 56.83 109.50 Td (material ) Tj ET Q q 0 0 0 rg BT 92.09 109.50 Td (to, ) Tj ET Q q 0 0 0 rg BT 104.87 109.50 Td (the ) Tj ET Q q 0 0 0 rg BT 119.58 109.50 Td (SEC.) Tj ET Q endstream endobj 37 0 obj <> endobj 38 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Information ) Tj ET Q q 0 0 0 rg BT 86.59 749.10 Td (relating ) Tj ET Q q 0 0 0 rg BT 119.95 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 130.56 749.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 171.13 749.10 Td (governance ) Tj ET Q q 0 0 0 rg BT 220.04 749.10 Td (at ) Tj ET Q q 0 0 0 rg BT 230.08 749.10 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 289.01 749.10 Td (Squibb, ) Tj ET Q q 0 0 0 rg BT 322.68 749.10 Td (including ) Tj ET Q q 0 0 0 rg BT 363.27 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 379.43 749.10 Td (Principles ) Tj ET Q q 0 0 0 rg BT 422.25 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 433.40 749.10 Td (Integrity) Tj ET Q q 0 0 0 rg BT 467.18 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 472.51 749.10 Td (Code ) Tj ET Q q 0 0 0 rg BT 496.44 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 507.59 749.10 Td (Ethics ) Tj ET Q q 0 0 0 rg BT 535.41 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 549.90 749.10 Td (Senior ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 75.89 737.10 Td (Of) Tj ET Q q 0 0 0 rg BT 86.26 737.10 Td (ficers, ) Tj ET Q q 0 0 0 rg BT 113.64 737.10 Td (Code ) Tj ET Q q 0 0 0 rg BT 137.43 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 148.44 737.10 Td (Business ) Tj ET Q q 0 0 0 rg BT 186.68 737.10 Td (Conduct ) Tj ET Q q 0 0 0 rg BT 223.24 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 240.36 737.10 Td (Ethics ) Tj ET Q q 0 0 0 rg BT 268.03 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 282.37 737.10 Td (Directors, ) Tj ET Q q 0 0 0 rg BT 324.75 737.10 Td (\(collectively) Tj ET Q q 0 0 0 rg BT 374.08 737.10 Td (, ) Tj ET Q q 0 0 0 rg BT 379.25 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 394.15 737.10 Td (“Codes”\), ) Tj ET Q q 0 0 0 rg BT 436.53 737.10 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 479.19 737.10 Td (Governance ) Tj ET Q q 0 0 0 rg BT 530.18 737.10 Td (Guidelines, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.32 725.10 Td (information ) Tj ET Q q 0 0 0 rg BT 103.41 725.10 Td (concerning ) Tj ET Q q 0 0 0 rg BT 150.71 725.10 Td (our ) Tj ET Q q 0 0 0 rg BT 166.92 725.10 Td (Executive ) Tj ET Q q 0 0 0 rg BT 209.78 725.10 Td (Committee, ) Tj ET Q q 0 0 0 rg BT 259.60 725.10 Td (Board ) Tj ET Q q 0 0 0 rg BT 286.92 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 298.13 725.10 Td (Directors, ) Tj ET Q q 0 0 0 rg BT 340.72 725.10 Td (including ) Tj ET Q q 0 0 0 rg BT 381.37 725.10 Td (Board ) Tj ET Q q 0 0 0 rg BT 408.69 725.10 Td (Committees ) Tj ET Q q 0 0 0 rg BT 459.90 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 477.22 725.10 Td (Committee ) Tj ET Q q 0 0 0 rg BT 524.54 725.10 Td (charters, ) Tj ET Q q 0 0 0 rg BT 561.56 725.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 86.64 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 97.30 713.10 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 156.29 713.10 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 187.50 713.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 228.15 713.10 Td (by ) Tj ET Q q 0 0 0 rg BT 241.02 713.10 Td (directors ) Tj ET Q q 0 0 0 rg BT 278.89 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 296.21 713.10 Td (executive ) Tj ET Q q 0 0 0 rg BT 337.39 713.10 Td (of) Tj ET Q q 0 0 0 rg BT 345.54 713.10 Td (ficers, ) Tj ET Q q 0 0 0 rg BT 373.13 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 382.68 713.10 Td (available ) Tj ET Q q 0 0 0 rg BT 421.64 713.10 Td (on ) Tj ET Q q 0 0 0 rg BT 434.52 713.10 Td (our ) Tj ET Q q 0 0 0 rg BT 450.73 713.10 Td (website ) Tj ET Q q 0 0 0 rg BT 484.16 713.10 Td (under ) Tj ET Q q 0 0 0 rg BT 509.80 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 524.90 713.10 Td (“Investors—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 78.07 701.10 Td (Governance” ) Tj ET Q q 0 0 0 rg BT 132.89 701.10 Td (caption ) Tj ET Q q 0 0 0 rg BT 164.41 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 180.93 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 190.79 701.10 Td (print ) Tj ET Q q 0 0 0 rg BT 211.76 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 221.62 701.10 Td (any ) Tj ET Q q 0 0 0 rg BT 238.14 701.10 Td (stockholder ) Tj ET Q q 0 0 0 rg BT 286.88 701.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 308.96 701.10 Td (request. ) Tj ET Q q 0 0 0 rg BT 341.96 701.10 Td (Any ) Tj ET Q q 0 0 0 rg BT 361.27 701.10 Td (waivers ) Tj ET Q q 0 0 0 rg BT 394.45 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 404.31 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 418.61 701.10 Td (Codes ) Tj ET Q q 0 0 0 rg BT 445.69 701.10 Td (by ) Tj ET Q q 0 0 0 rg BT 457.77 701.10 Td (directors ) Tj ET Q q 0 0 0 rg BT 494.84 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 505.25 701.10 Td (executive ) Tj ET Q q 0 0 0 rg BT 545.65 701.10 Td (of) Tj ET Q q 0 0 0 rg BT 553.80 701.10 Td (ficers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.73 689.10 Td (any ) Tj ET Q q 0 0 0 rg BT 69.46 689.10 Td (material ) Tj ET Q q 0 0 0 rg BT 104.51 689.10 Td (amendment ) Tj ET Q q 0 0 0 rg BT 153.45 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 163.52 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 178.03 689.10 Td (Code ) Tj ET Q q 0 0 0 rg BT 201.43 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 212.05 689.10 Td (Business ) Tj ET Q q 0 0 0 rg BT 249.90 689.10 Td (Conduct ) Tj ET Q q 0 0 0 rg BT 286.08 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 302.81 689.10 Td (Ethics ) Tj ET Q q 0 0 0 rg BT 330.10 689.10 Td (for ) Tj ET Q q 0 0 0 rg BT 344.05 689.10 Td (Directors ) Tj ET Q q 0 0 0 rg BT 383.55 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 400.28 689.10 Td (Code ) Tj ET Q q 0 0 0 rg BT 423.68 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 434.30 689.10 Td (Ethics ) Tj ET Q q 0 0 0 rg BT 461.59 689.10 Td (for ) Tj ET Q q 0 0 0 rg BT 475.54 689.10 Td (Senior ) Tj ET Q q 0 0 0 rg BT 503.94 689.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 543.44 689.10 Td (Of) Tj ET Q q 0 0 0 rg BT 553.81 689.10 Td (ficers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (will ) Tj ET Q q 0 0 0 rg BT 54.67 677.10 Td (be ) Tj ET Q q 0 0 0 rg BT 67.22 677.10 Td (posted ) Tj ET Q q 0 0 0 rg BT 96.43 677.10 Td (promptly ) Tj ET Q q 0 0 0 rg BT 136.21 677.10 Td (on ) Tj ET Q q 0 0 0 rg BT 149.32 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 165.76 677.10 Td (website. ) Tj ET Q q 0 0 0 rg BT 201.92 677.10 Td (Information ) Tj ET Q q 0 0 0 rg BT 252.79 677.10 Td (relating ) Tj ET Q q 0 0 0 rg BT 286.44 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 297.33 677.10 Td (stockholder ) Tj ET Q q 0 0 0 rg BT 347.10 677.10 Td (services, ) Tj ET Q q 0 0 0 rg BT 384.92 677.10 Td (including ) Tj ET Q q 0 0 0 rg BT 425.80 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 442.24 677.10 Td (Dividend ) Tj ET Q q 0 0 0 rg BT 482.57 677.10 Td (Reinvestment ) Tj ET Q q 0 0 0 rg BT 540.67 677.10 Td (Plan ) Tj ET Q q 0 0 0 rg BT 561.56 677.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 61.67 665.10 Td (deposit ) Tj ET Q q 0 0 0 rg BT 93.47 665.10 Td (of ) Tj ET Q q 0 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(available ) Tj ET Q q 0 0 0 rg BT 222.07 653.10 Td (on ) Tj ET Q q 0 0 0 rg BT 234.57 653.10 Td (our ) Tj ET Q q 0 0 0 rg BT 250.40 653.10 Td (website ) Tj ET Q q 0 0 0 rg BT 283.45 653.10 Td (under ) Tj ET Q q 0 0 0 rg BT 308.72 653.10 Td (the ) Tj ET Q q 0 0 0 rg BT 323.44 653.10 Td ("Responsibility" ) Tj ET Q q 0 0 0 rg BT 391.88 653.10 Td (caption.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 629.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.88 629.10 Td (incorporate ) Tj ET Q q 0 0 0 rg BT 100.21 629.10 Td (by ) Tj ET Q q 0 0 0 rg BT 113.01 629.10 Td (reference ) Tj ET Q q 0 0 0 rg BT 152.99 629.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 182.99 629.10 Td (information ) Tj ET Q q 0 0 0 rg BT 233.01 629.10 Td (from ) Tj ET Q q 0 0 0 rg BT 255.25 629.10 Td (parts ) Tj ET Q q 0 0 0 rg BT 277.48 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 288.61 629.10 Td (our ) Tj ET Q q 0 0 0 rg BT 304.75 629.10 Td (proxy ) Tj ET Q q 0 0 0 rg BT 330.88 629.10 Td (statement ) Tj ET Q q 0 0 0 rg BT 372.00 629.10 Td (for ) Tj ET Q q 0 0 0 rg BT 386.46 629.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.47 629.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.47 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 423.66 629.10 Td (Annual ) Tj ET Q q 0 0 0 rg BT 455.89 629.10 Td (Meeting ) Tj ET Q q 0 0 0 rg BT 492.02 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 503.15 629.10 Td (Stockholders. ) Tj ET Q q 0 0 0 rg BT 560.47 629.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (SEC ) Tj ET Q q 0 0 0 rg BT 56.73 617.10 Td (allows ) Tj ET Q q 0 0 0 rg BT 85.22 617.10 Td (us ) Tj ET Q q 0 0 0 rg BT 96.50 617.10 Td (to ) Tj ET Q q 0 0 0 rg BT 106.67 617.10 Td (disclose ) Tj ET Q q 0 0 0 rg BT 141.27 617.10 Td (important ) Tj ET Q q 0 0 0 rg BT 182.54 617.10 Td (information ) Tj ET Q q 0 0 0 rg BT 232.14 617.10 Td (by ) Tj ET Q q 0 0 0 rg BT 244.52 617.10 Td (referring ) Tj ET Q q 0 0 0 rg BT 281.88 617.10 Td (to ) Tj ET Q q 0 0 0 rg BT 292.05 617.10 Td (it ) Tj ET Q q 0 0 0 rg BT 299.99 617.10 Td (in ) Tj ET Q q 0 0 0 rg BT 310.16 617.10 Td (that ) Tj ET Q q 0 0 0 rg BT 327.54 617.10 Td (manner) Tj ET Q q 0 0 0 rg BT 356.97 617.10 Td (. ) Tj ET Q q 0 0 0 rg BT 361.86 617.10 Td (Please ) Tj ET Q q 0 0 0 rg BT 389.79 617.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 411.05 617.10 Td (to ) Tj ET Q q 0 0 0 rg BT 421.21 617.10 Td (such ) Tj ET Q q 0 0 0 rg BT 441.93 617.10 Td (information. ) Tj ET Q q 0 0 0 rg BT 494.03 617.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 511.97 617.10 Td (proxy ) Tj ET Q q 0 0 0 rg BT 537.68 617.10 Td (statement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (for ) Tj ET Q q 0 0 0 rg BT 51.02 605.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.60 605.10 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 86.60 605.10 Td ( ) Tj ET Q q 0 0 0 rg BT 89.21 605.10 Td (Annual ) Tj ET Q q 0 0 0 rg BT 122.01 605.10 Td (Meeting ) Tj ET Q q 0 0 0 rg BT 158.70 605.10 Td (of ) Tj ET Q q 0 0 0 rg BT 170.39 605.10 Td (Stockholders ) Tj ET Q q 0 0 0 rg BT 225.96 605.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 243.76 605.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.76 605.10 Td ( ) Tj ET Q q 0 0 0 rg BT 266.38 605.10 Td (Annual ) Tj ET Q q 0 0 0 rg BT 299.18 605.10 Td (Report ) Tj ET Q q 0 0 0 rg BT 329.75 605.10 Td (will ) Tj ET Q q 0 0 0 rg BT 348.67 605.10 Td (be ) Tj ET Q q 0 0 0 rg BT 361.47 605.10 Td (available ) Tj ET Q q 0 0 0 rg BT 400.91 605.10 Td (on ) Tj ET Q q 0 0 0 rg BT 414.27 605.10 Td (our ) Tj ET Q q 0 0 0 rg BT 430.96 605.10 Td (website ) Tj ET Q q 0 0 0 rg BT 464.87 605.10 Td (under ) Tj ET Q q 0 0 0 rg BT 491.00 605.10 Td (the ) Tj ET Q q 0 0 0 rg BT 506.57 605.10 Td (“Investors—SEC ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (Filings” ) Tj ET Q q 0 0 0 rg BT 70.73 593.10 Td (caption ) Tj ET Q q 0 0 0 rg BT 102.66 593.10 Td (on ) Tj ET Q q 0 0 0 rg BT 115.16 593.10 Td (or ) Tj ET Q q 0 0 0 rg BT 125.99 593.10 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 150.71 593.10 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 194.31 593.10 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.31 593.10 Td (.) Tj ET Q endstream endobj 39 0 obj <> endobj 40 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (19) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 746.23 Td (Item 1A.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 746.23 Td (RISK F) Tj ET Q q 0 0 0 rg BT 127.32 746.23 Td (ACT) Tj ET Q q 0 0 0 rg BT 148.25 746.23 Td (ORS.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 723.80 Td (Any ) Tj ET Q q 0 0 0 rg BT 54.97 723.80 Td (of ) Tj ET Q q 0 0 0 rg BT 65.06 723.80 Td (the ) Tj ET Q q 0 0 0 rg BT 79.03 723.80 Td (factors ) Tj ET Q q 0 0 0 rg BT 107.99 723.80 Td (described ) Tj ET Q q 0 0 0 rg BT 148.06 723.80 Td (below ) Tj ET Q q 0 0 0 rg BT 174.25 723.80 Td (could ) Tj ET Q q 0 0 0 rg BT 198.22 723.80 Td (significantly ) Tj ET Q q 0 0 0 rg BT 249.96 723.80 Td (and ) Tj ET Q q 0 0 0 rg BT 266.15 723.80 Td (negatively ) Tj ET Q q 0 0 0 rg BT 309.55 723.80 Td (af) Tj ET Q q 0 0 0 rg BT 317.14 723.80 Td (fect ) Tj ET Q q 0 0 0 rg BT 333.88 723.80 Td (our ) Tj ET Q q 0 0 0 rg BT 348.96 723.80 Td (business, ) Tj ET Q q 0 0 0 rg BT 387.11 723.80 Td (prospects, ) Tj ET Q q 0 0 0 rg BT 429.13 723.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 465.86 723.80 Td (condition, ) Tj ET Q q 0 0 0 rg BT 507.89 723.80 Td (operating ) Tj ET Q q 0 0 0 rg BT 547.41 723.80 Td (results, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 711.80 Td (or ) Tj ET Q q 0 0 0 rg BT 47.17 711.80 Td (credit ) Tj ET Q q 0 0 0 rg BT 72.78 711.80 Td (ratings, ) Tj ET Q q 0 0 0 rg BT 105.34 711.80 Td (which ) Tj ET Q q 0 0 0 rg BT 132.63 711.80 Td (could ) Tj ET Q q 0 0 0 rg BT 157.69 711.80 Td (cause ) Tj ET Q q 0 0 0 rg BT 182.74 711.80 Td (the ) Tj ET Q q 0 0 0 rg BT 197.80 711.80 Td (trading ) Tj ET Q q 0 0 0 rg BT 228.97 711.80 Td (price ) Tj ET Q q 0 0 0 rg BT 251.80 711.80 Td (of ) Tj ET Q q 0 0 0 rg BT 262.97 711.80 Td (our ) Tj ET Q q 0 0 0 rg BT 279.15 711.80 Td (common ) Tj ET Q q 0 0 0 rg BT 316.99 711.80 Td (stock ) Tj ET Q q 0 0 0 rg BT 340.94 711.80 Td (to ) Tj ET Q q 0 0 0 rg BT 351.56 711.80 Td (decline. ) Tj ET Q q 0 0 0 rg BT 385.15 711.80 Td (Additional ) Tj ET Q q 0 0 0 rg BT 430.77 711.80 Td (risks ) Tj ET Q q 0 0 0 rg BT 452.50 711.80 Td (and ) Tj ET Q q 0 0 0 rg BT 469.79 711.80 Td (uncertainties ) Tj ET Q q 0 0 0 rg BT 523.72 711.80 Td (not ) Tj ET Q q 0 0 0 rg BT 539.34 711.80 Td (presently ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 699.80 Td (known ) Tj ET Q q 0 0 0 rg BT 65.72 699.80 Td (to ) Tj ET Q q 0 0 0 rg BT 76.00 699.80 Td (us, ) Tj ET Q q 0 0 0 rg BT 89.89 699.80 Td (or ) Tj ET Q q 0 0 0 rg BT 100.72 699.80 Td (risks ) Tj ET Q q 0 0 0 rg BT 122.11 699.80 Td (that ) Tj ET Q q 0 0 0 rg BT 139.61 699.80 Td (we ) Tj ET Q q 0 0 0 rg BT 153.77 699.80 Td (currently ) Tj ET Q q 0 0 0 rg BT 192.36 699.80 Td (consider ) Tj ET Q q 0 0 0 rg BT 228.74 699.80 Td (immaterial, ) Tj ET Q q 0 0 0 rg BT 277.05 699.80 Td (could ) Tj ET Q q 0 0 0 rg BT 301.77 699.80 Td (also ) Tj ET Q q 0 0 0 rg BT 320.38 699.80 Td (impair ) Tj ET Q q 0 0 0 rg BT 348.98 699.80 Td (our ) Tj ET Q q 0 0 0 rg BT 364.81 699.80 Td (operations ) Tj ET Q q 0 0 0 rg BT 408.97 699.80 Td (or ) Tj ET Q q 0 0 0 rg BT 419.80 699.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 457.28 699.80 Td (condition.) 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(significantly ) Tj ET Q q 0 0 0 rg BT 361.40 627.80 Td (and ) Tj ET Q q 0 0 0 rg BT 379.11 627.80 Td (there ) Tj ET Q q 0 0 0 rg BT 402.36 627.80 Td (may ) Tj ET Q q 0 0 0 rg BT 421.72 627.80 Td (be ) Tj ET Q q 0 0 0 rg BT 433.31 627.80 Td (an ) Tj ET Q q 0 0 0 rg BT 446.01 627.80 Td (adverse ) Tj ET Q q 0 0 0 rg BT 479.26 627.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 509.18 627.80 Td (on ) Tj ET Q q 0 0 0 rg BT 521.89 627.80 Td (our ) Tj ET Q q 0 0 0 rg BT 538.49 627.80 Td (business, ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 615.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 75.73 615.80 Td (condition ) Tj ET Q q 0 0 0 rg BT 117.12 615.80 Td (or ) Tj ET Q q 0 0 0 rg BT 128.51 615.80 Td (results ) Tj ET Q q 0 0 0 rg BT 158.25 615.80 Td (of ) Tj ET Q q 0 0 0 rg BT 169.08 615.80 Td (operations.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 603.80 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 603.80 Td (e ) Tj ET Q q 0 0 0 rg BT 50.65 603.80 Td (ar) Tj ET Q q 0 0 0 rg BT 59.17 603.80 Td (e ) Tj ET Q q 0 0 0 rg BT 66.41 603.80 Td (focusing ) Tj ET Q q 0 0 0 rg BT 103.09 603.80 Td (our ) Tj ET Q q 0 0 0 rg BT 119.78 603.80 Td (efforts ) Tj ET Q q 0 0 0 rg BT 148.13 603.80 Td (and ) Tj ET Q q 0 0 0 rg BT 165.93 603.80 Td (r) Tj ET Q q 0 0 0 rg BT 169.45 603.80 Td (esour) Tj ET Q q 0 0 0 rg BT 191.30 603.80 Td (ces ) Tj ET Q q 0 0 0 rg BT 206.87 603.80 Td (in ) Tj ET Q q 0 0 0 rg BT 217.45 603.80 Td (disease ) Tj ET Q q 0 0 0 rg BT 249.68 603.80 Td (ar) Tj ET Q q 0 0 0 rg BT 258.20 603.80 Td (eas ) Tj ET Q q 0 0 0 rg BT 274.33 603.80 Td (of ) Tj ET Q q 0 0 0 rg BT 284.91 603.80 Td (high ) Tj ET Q q 0 0 0 rg BT 305.48 603.80 Td (unmet ) Tj ET Q q 0 0 0 rg BT 332.72 603.80 Td (need. ) Tj ET Q q 0 0 0 rg BT 356.89 603.80 Td (W) Tj ET Q q 0 0 0 rg BT 364.67 603.80 Td (ith ) Tj ET Q q 0 0 0 rg BT 378.03 603.80 Td (our ) Tj ET Q q 0 0 0 rg BT 394.72 603.80 Td (mor) Tj ET Q q 0 0 0 rg BT 410.46 603.80 Td (e ) Tj ET Q q 0 0 0 rg BT 417.69 603.80 Td (focused ) Tj ET Q q 0 0 0 rg BT 451.04 603.80 Td (portfolio, ) Tj ET Q q 0 0 0 rg BT 491.34 603.80 Td (investors ) Tj ET Q q 0 0 0 rg BT 530.25 603.80 Td (ar) Tj ET Q q 0 0 0 rg BT 538.77 603.80 Td (e ) Tj ET Q q 0 0 0 rg BT 546.00 603.80 Td (placing ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 591.80 Td (heightened ) Tj ET Q q 0 0 0 rg BT 82.13 591.80 Td (scrutiny ) Tj ET Q q 0 0 0 rg BT 116.60 591.80 Td (on ) Tj ET Q q 0 0 0 rg BT 128.86 591.80 Td (some ) Tj ET Q q 0 0 0 rg BT 151.67 591.80 Td (of ) Tj ET Q q 0 0 0 rg BT 161.71 591.80 Td (our ) Tj ET Q q 0 0 0 rg BT 177.85 591.80 Td (pr) Tj ET Q q 0 0 0 rg BT 186.38 591.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 214.74 591.80 Td (or ) Tj ET Q q 0 0 0 rg BT 225.89 591.80 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 267.58 591.80 Td (compounds. ) Tj ET Q q 0 0 0 rg BT 317.89 591.80 Td (In ) Tj ET Q q 0 0 0 rg BT 328.48 591.80 Td (particular) Tj ET Q q 0 0 0 rg BT 367.93 591.80 Td (, ) Tj ET Q q 0 0 0 rg BT 372.68 591.80 Td (Opdivo ) Tj ET Q q 0 0 0 rg BT 404.38 591.80 Td (is ) Tj ET Q q 0 0 0 rg BT 413.31 591.80 Td (the ) Tj ET Q q 0 0 0 rg BT 427.78 591.80 Td (backbone ) Tj ET Q q 0 0 0 rg BT 468.35 591.80 Td (of ) Tj ET Q q 0 0 0 rg BT 478.39 591.80 Td (our ) Tj ET Q q 0 0 0 rg BT 494.54 591.80 Td (IO ) Tj ET Q q 0 0 0 rg BT 507.35 591.80 Td (portfolio. ) Tj ET Q q 0 0 0 rg BT 547.11 591.80 Td (During ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 579.80 Td (2017, ) Tj ET Q q 0 0 0 rg BT 60.69 579.80 Td (we ) Tj ET Q q 0 0 0 rg BT 73.98 579.80 Td (announced ) Tj ET Q q 0 0 0 rg BT 120.04 579.80 Td (multiple ) Tj ET Q q 0 0 0 rg BT 155.00 579.80 Td (r) Tj ET Q q 0 0 0 rg BT 158.53 579.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 199.04 579.80 Td (milestones ) Tj ET Q q 0 0 0 rg BT 243.44 579.80 Td (for ) Tj ET Q q 0 0 0 rg BT 257.30 579.80 Td (Opdivo, ) Tj ET Q q 0 0 0 rg BT 291.42 579.80 Td (including ) Tj ET Q q 0 0 0 rg BT 331.38 579.80 Td (the ) Tj ET Q q 0 0 0 rg BT 345.79 579.80 Td (early ) Tj ET Q q 0 0 0 rg BT 368.52 579.80 Td (stoppage ) Tj ET Q q 0 0 0 rg BT 406.81 579.80 Td (of ) Tj ET Q q 0 0 0 rg BT 416.78 579.80 Td (certain ) Tj ET Q q 0 0 0 rg BT 447.29 579.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 479.47 579.80 Td (studies ) Tj ET Q q 0 0 0 rg BT 509.43 579.80 Td (for ) Tj ET Q q 0 0 0 rg BT 523.29 579.80 Td (meeting ) Tj ET Q q 0 0 0 rg BT 557.13 579.80 Td (their ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 567.80 Td (endpoints ) Tj ET Q q 0 0 0 rg BT 77.02 567.80 Td (and ) Tj ET Q q 0 0 0 rg BT 94.16 567.80 Td (label ) Tj ET Q q 0 0 0 rg BT 116.29 567.80 Td (expansions ) Tj ET Q q 0 0 0 rg BT 162.86 567.80 Td (for ) Tj ET Q q 0 0 0 rg BT 176.67 567.80 Td (new ) Tj ET Q q 0 0 0 rg BT 194.91 567.80 Td (indications. ) Tj ET Q q 0 0 0 rg BT 243.99 567.80 Td (W) Tj ET Q q 0 0 0 rg BT 251.40 567.80 Td (e ) Tj ET Q q 0 0 0 rg BT 257.97 567.80 Td (have, ) Tj ET Q q 0 0 0 rg BT 281.49 567.80 Td (however) Tj ET Q q 0 0 0 rg BT 314.26 567.80 Td (, ) Tj ET Q q 0 0 0 rg BT 318.89 567.80 Td (also ) Tj ET Q q 0 0 0 rg BT 337.70 567.80 Td (experienced ) Tj ET Q q 0 0 0 rg BT 388.13 567.80 Td (setbacks ) Tj ET Q q 0 0 0 rg BT 424.14 567.80 Td (and ) Tj ET Q q 0 0 0 rg BT 441.28 567.80 Td (may ) Tj ET Q q 0 0 0 rg BT 460.07 567.80 Td (continue ) Tj ET Q q 0 0 0 rg BT 496.64 567.80 Td (to ) Tj ET Q q 0 0 0 rg BT 506.56 567.80 Td (do ) Tj ET Q q 0 0 0 rg BT 518.69 567.80 Td (so ) Tj ET Q q 0 0 0 rg BT 529.72 567.80 Td (as ) Tj ET Q q 0 0 0 rg BT 540.75 567.80 Td (ther) Tj ET Q q 0 0 0 rg BT 556.48 567.80 Td (e ) Tj ET Q q 0 0 0 rg BT 563.06 567.80 Td (ar) Tj ET Q q 0 0 0 rg BT 571.58 567.80 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 555.80 Td (further ) Tj ET Q q 0 0 0 rg BT 68.21 555.80 Td (developments ) Tj ET Q q 0 0 0 rg BT 127.06 555.80 Td (in ) Tj ET Q q 0 0 0 rg BT 139.27 555.80 Td (our ) Tj ET Q q 0 0 0 rg BT 157.59 555.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 192.01 555.80 Td (studies. ) Tj ET Q q 0 0 0 rg BT 226.72 555.80 Td (In ) Tj ET Q q 0 0 0 rg BT 239.48 555.80 Td (2018, ) Tj ET Q q 0 0 0 rg BT 266.40 555.80 Td (we ) Tj ET Q q 0 0 0 rg BT 281.94 555.80 Td (expect ) Tj ET Q q 0 0 0 rg BT 311.90 555.80 Td (to ) Tj ET Q q 0 0 0 rg BT 324.11 555.80 Td (r) Tj ET Q q 0 0 0 rg BT 327.63 555.80 Td (eceive ) Tj ET Q q 0 0 0 rg BT 357.03 555.80 Td (further ) Tj ET Q q 0 0 0 rg BT 389.24 555.80 Td (data ) Tj ET Q q 0 0 0 rg BT 411.45 555.80 Td (fr) Tj ET Q q 0 0 0 rg BT 417.75 555.80 Td (om ) Tj ET Q q 0 0 0 rg BT 434.40 555.80 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 471.60 555.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 506.02 555.80 Td (studies ) Tj ET Q q 0 0 0 rg BT 538.23 555.80 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 543.80 Td (CheckMate-227, ) Tj ET Q q 0 0 0 rg BT 104.57 543.80 Td (a ) Tj ET Q q 0 0 0 rg BT 111.78 543.80 Td (combination ) Tj ET Q q 0 0 0 rg BT 163.99 543.80 Td (study ) Tj ET Q q 0 0 0 rg BT 187.31 543.80 Td (in ) Tj ET Q q 0 0 0 rg BT 197.30 543.80 Td (the ) Tj ET Q q 0 0 0 rg BT 211.73 543.80 Td (first-line ) Tj ET Q q 0 0 0 rg BT 248.38 543.80 Td (lung ) Tj ET Q q 0 0 0 rg BT 268.37 543.80 Td (cancer ) Tj ET Q q 0 0 0 rg BT 297.79 543.80 Td (setting ) Tj ET Q q 0 0 0 rg BT 326.66 543.80 Td (and ) Tj ET Q q 0 0 0 rg BT 343.88 543.80 Td (decisions ) Tj ET Q q 0 0 0 rg BT 383.30 543.80 Td (fr) Tj ET Q q 0 0 0 rg BT 389.60 543.80 Td (om ) Tj ET Q q 0 0 0 rg BT 404.03 543.80 Td (health ) Tj ET Q q 0 0 0 rg BT 431.24 543.80 Td (authorities ) Tj ET Q q 0 0 0 rg BT 476.79 543.80 Td (r) Tj ET Q q 0 0 0 rg BT 480.31 543.80 Td (egar) Tj ET Q q 0 0 0 rg BT 498.27 543.80 Td (ding ) Tj ET Q q 0 0 0 rg BT 518.25 543.80 Td (potential ) Tj ET Q q 0 0 0 rg BT 556.02 543.80 Td (label ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 531.80 Td (expansions.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 507.80 Td (The ) Tj ET Q q 0 0 0 rg BT 54.08 507.80 Td (announcement ) Tj ET Q q 0 0 0 rg BT 115.47 507.80 Td (of ) Tj ET Q q 0 0 0 rg BT 126.33 507.80 Td (data ) Tj ET Q q 0 0 0 rg BT 147.19 507.80 Td (fr) Tj ET Q q 0 0 0 rg BT 153.49 507.80 Td (om ) Tj ET Q q 0 0 0 rg BT 168.79 507.80 Td (our ) Tj ET Q q 0 0 0 rg BT 185.76 507.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 218.82 507.80 Td (studies, ) Tj ET Q q 0 0 0 rg BT 252.18 507.80 Td (or ) Tj ET Q q 0 0 0 rg BT 264.15 507.80 Td (those ) Tj ET Q q 0 0 0 rg BT 288.34 507.80 Td (of ) Tj ET Q q 0 0 0 rg BT 299.20 507.80 Td (our ) Tj ET Q q 0 0 0 rg BT 316.17 507.80 Td (competitors, ) Tj ET Q q 0 0 0 rg BT 368.96 507.80 Td (or ) Tj ET Q q 0 0 0 rg BT 380.93 507.80 Td (news ) Tj ET Q q 0 0 0 rg BT 404.01 507.80 Td (of ) Tj ET Q q 0 0 0 rg BT 414.87 507.80 Td (any ) Tj ET Q q 0 0 0 rg BT 432.38 507.80 Td (developments ) Tj ET Q q 0 0 0 rg BT 489.89 507.80 Td (r) Tj ET Q q 0 0 0 rg BT 493.41 507.80 Td (elated ) Tj ET Q q 0 0 0 rg BT 520.92 507.80 Td (to ) Tj ET Q q 0 0 0 rg BT 531.78 507.80 Td (our) Tj ET Q q 0 0 0 rg BT 544.56 507.80 Td (, ) Tj ET Q q 0 0 0 rg BT 550.14 507.80 Td (or ) Tj ET Q q 0 0 0 rg BT 562.11 507.80 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 495.80 Td (competitors', ) Tj ET Q q 0 0 0 rg BT 90.68 495.80 Td (IO ) Tj ET Q q 0 0 0 rg BT 104.05 495.80 Td (pr) Tj ET Q q 0 0 0 rg BT 112.58 495.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 141.51 495.80 Td (or ) Tj ET Q q 0 0 0 rg BT 153.22 495.80 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 195.48 495.80 Td (compounds, ) Tj ET Q q 0 0 0 rg BT 246.36 495.80 Td (such ) Tj ET Q q 0 0 0 rg BT 267.51 495.80 Td (as ) Tj ET Q q 0 0 0 rg BT 279.22 495.80 Td (Opdivo, ) Tj ET Q q 0 0 0 rg BT 313.99 495.80 Td (may ) Tj ET Q q 0 0 0 rg BT 333.47 495.80 Td (cause ) Tj ET Q q 0 0 0 rg BT 359.06 495.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 404.11 495.80 Td (volatility ) Tj ET Q q 0 0 0 rg BT 442.48 495.80 Td (in ) Tj ET Q q 0 0 0 rg BT 453.08 495.80 Td (our ) Tj ET Q q 0 0 0 rg BT 469.80 495.80 Td (stock ) Tj ET Q q 0 0 0 rg BT 493.17 495.80 Td (price ) Tj ET Q q 0 0 0 rg BT 516.54 495.80 Td (and ) Tj ET Q q 0 0 0 rg BT 534.36 495.80 Td (depending ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 483.80 Td (on ) Tj ET Q q 0 0 0 rg BT 47.89 483.80 Td (the ) Tj ET Q q 0 0 0 rg BT 62.00 483.80 Td (news, ) Tj ET Q q 0 0 0 rg BT 86.39 483.80 Td (may ) Tj ET Q q 0 0 0 rg BT 104.95 483.80 Td (r) Tj ET Q q 0 0 0 rg BT 108.47 483.80 Td (esult ) Tj ET Q q 0 0 0 rg BT 129.24 483.80 Td (in ) Tj ET Q q 0 0 0 rg BT 138.92 483.80 Td (an ) Tj ET Q q 0 0 0 rg BT 150.81 483.80 Td (adverse ) Tj ET Q q 0 0 0 rg BT 183.80 483.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 212.91 483.80 Td (on ) Tj ET Q q 0 0 0 rg BT 224.80 483.80 Td (our ) Tj ET Q q 0 0 0 rg BT 240.58 483.80 Td (business, ) Tj ET Q q 0 0 0 rg BT 278.87 483.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 316.31 483.80 Td (condition ) Tj ET Q q 0 0 0 rg BT 355.98 483.80 Td (or ) Tj ET Q q 0 0 0 rg BT 366.76 483.80 Td (r) Tj ET Q q 0 0 0 rg BT 370.28 483.80 Td (esults ) Tj ET Q q 0 0 0 rg BT 394.95 483.80 Td (of ) Tj ET Q q 0 0 0 rg BT 404.62 483.80 Td (operation. ) Tj ET Q q 0 0 0 rg BT 447.90 483.80 Td (Furthermor) Tj ET Q q 0 0 0 rg BT 494.75 483.80 Td (e, ) Tj ET Q q 0 0 0 rg BT 503.58 483.80 Td (the ) Tj ET Q q 0 0 0 rg BT 517.69 483.80 Td (announcement ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 471.80 Td (of ) Tj ET Q q 0 0 0 rg BT 46.31 471.80 Td (any ) Tj ET Q q 0 0 0 rg BT 63.28 471.80 Td (negative ) Tj ET Q q 0 0 0 rg BT 99.68 471.80 Td (or ) Tj ET Q q 0 0 0 rg BT 111.10 471.80 Td (unexpected ) Tj ET Q q 0 0 0 rg BT 158.60 471.80 Td (data ) Tj ET Q q 0 0 0 rg BT 178.91 471.80 Td (or ) Tj ET Q q 0 0 0 rg BT 190.33 471.80 Td (the ) Tj ET Q q 0 0 0 rg BT 205.07 471.80 Td (discontinuation ) Tj ET Q q 0 0 0 rg BT 269.82 471.80 Td (of ) Tj ET Q q 0 0 0 rg BT 280.13 471.80 Td (development ) Tj ET Q q 0 0 0 rg BT 333.19 471.80 Td (of ) Tj ET Q q 0 0 0 rg BT 343.50 471.80 Td (any ) Tj ET Q q 0 0 0 rg BT 360.47 471.80 Td (of ) Tj ET Q q 0 0 0 rg BT 370.78 471.80 Td (our ) Tj ET Q q 0 0 0 rg BT 387.20 471.80 Td (key ) Tj ET Q q 0 0 0 rg BT 403.04 471.80 Td (IO ) Tj ET Q q 0 0 0 rg BT 416.12 471.80 Td (compounds, ) Tj ET Q q 0 0 0 rg BT 466.70 471.80 Td (whether ) Tj ET Q q 0 0 0 rg BT 501.45 471.80 Td (alone ) Tj ET Q q 0 0 0 rg BT 526.20 471.80 Td (or ) Tj ET Q q 0 0 0 rg BT 537.62 471.80 Td (as ) Tj ET Q q 0 0 0 rg BT 549.04 471.80 Td (part ) Tj ET Q q 0 0 0 rg BT 568.24 471.80 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 459.80 Td (a ) Tj ET Q q 0 0 0 rg BT 44.68 459.80 Td (combination ) Tj ET Q q 0 0 0 rg BT 98.36 459.80 Td (therapy) Tj ET Q q 0 0 0 rg BT 128.36 459.80 Td (, ) Tj ET Q q 0 0 0 rg BT 134.54 459.80 Td (any ) Tj ET Q q 0 0 0 rg BT 152.66 459.80 Td (delay ) Tj ET Q q 0 0 0 rg BT 178.00 459.80 Td (in ) Tj ET Q q 0 0 0 rg BT 189.46 459.80 Td (our ) Tj ET Q q 0 0 0 rg BT 207.04 459.80 Td (anticipated ) Tj ET Q q 0 0 0 rg BT 255.71 459.80 Td (timelines ) Tj ET Q q 0 0 0 rg BT 295.50 459.80 Td (for ) Tj ET Q q 0 0 0 rg BT 310.85 459.80 Td (filing ) Tj ET Q q 0 0 0 rg BT 335.65 459.80 Td (for ) Tj ET Q q 0 0 0 rg BT 351.00 459.80 Td (r) Tj ET Q q 0 0 0 rg BT 354.52 459.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 396.53 459.80 Td (appr) Tj ET Q q 0 0 0 rg BT 415.05 459.80 Td (oval ) Tj ET Q q 0 0 0 rg BT 435.95 459.80 Td (or ) Tj ET Q q 0 0 0 rg BT 448.52 459.80 Td (a ) Tj ET Q q 0 0 0 rg BT 457.21 459.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 503.11 459.80 Td (advancement ) Tj ET Q q 0 0 0 rg BT 559.55 459.80 Td (of ) Tj ET Q q 0 0 0 rg BT 571.01 459.80 Td (a ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 447.80 Td (competitor) Tj ET Q q 0 0 0 rg BT 78.22 447.80 Td (, ) Tj ET Q q 0 0 0 rg BT 83.39 447.80 Td (may ) Tj ET Q q 0 0 0 rg BT 102.72 447.80 Td (cause ) Tj ET Q q 0 0 0 rg BT 128.16 447.80 Td (our ) Tj ET Q q 0 0 0 rg BT 144.73 447.80 Td (stock ) Tj ET Q q 0 0 0 rg BT 167.95 447.80 Td (price ) Tj ET Q q 0 0 0 rg BT 191.17 447.80 Td (to ) Tj ET Q q 0 0 0 rg BT 201.62 447.80 Td (decline ) Tj ET Q q 0 0 0 rg BT 233.16 447.80 Td (significantly ) Tj ET Q q 0 0 0 rg BT 285.27 447.80 Td (and ) Tj ET Q q 0 0 0 rg BT 302.94 447.80 Td (may ) Tj ET Q q 0 0 0 rg BT 322.28 447.80 Td (have ) Tj ET Q q 0 0 0 rg BT 343.83 447.80 Td (an ) Tj ET Q q 0 0 0 rg BT 356.50 447.80 Td (adverse ) Tj ET Q q 0 0 0 rg BT 390.27 447.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 420.16 447.80 Td (on ) Tj ET Q q 0 0 0 rg BT 432.83 447.80 Td (our ) Tj ET Q q 0 0 0 rg BT 449.39 447.80 Td (business, ) Tj ET Q q 0 0 0 rg BT 488.46 447.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 526.68 447.80 Td (condition ) Tj ET Q q 0 0 0 rg BT 567.13 447.80 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 435.80 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 435.80 Td (esults ) Tj ET Q q 0 0 0 rg BT 64.98 435.80 Td (of ) Tj ET Q q 0 0 0 rg BT 75.44 435.80 Td (operations. ) Tj ET Q q 0 0 0 rg BT 123.40 435.80 Td (Ther) Tj ET Q q 0 0 0 rg BT 141.92 435.80 Td (e ) Tj ET Q q 0 0 0 rg BT 149.04 435.80 Td (is ) Tj ET Q q 0 0 0 rg BT 158.39 435.80 Td (no ) Tj ET Q q 0 0 0 rg BT 171.07 435.80 Td (assurance ) Tj ET Q q 0 0 0 rg BT 214.30 435.80 Td (that ) Tj ET Q q 0 0 0 rg BT 232.54 435.80 Td (data ) Tj ET Q q 0 0 0 rg BT 253.00 435.80 Td (fr) Tj ET Q q 0 0 0 rg BT 259.30 435.80 Td (om ) Tj ET Q q 0 0 0 rg BT 274.20 435.80 Td (our ) Tj ET Q q 0 0 0 rg BT 290.77 435.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 323.44 435.80 Td (studies ) Tj ET Q q 0 0 0 rg BT 353.90 435.80 Td (will ) Tj ET Q q 0 0 0 rg BT 371.59 435.80 Td (support ) Tj ET Q q 0 0 0 rg BT 404.83 435.80 Td (filings ) Tj ET Q q 0 0 0 rg BT 432.51 435.80 Td (for ) Tj ET Q q 0 0 0 rg BT 446.86 435.80 Td (r) Tj ET Q q 0 0 0 rg BT 450.38 435.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 491.39 435.80 Td (appr) Tj ET Q q 0 0 0 rg BT 509.91 435.80 Td (oval, ) Tj ET Q q 0 0 0 rg BT 532.31 435.80 Td (or ) Tj ET Q q 0 0 0 rg BT 543.88 435.80 Td (that ) Tj ET Q q 0 0 0 rg BT 562.12 435.80 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 423.80 Td (key ) Tj ET Q q 0 0 0 rg BT 51.90 423.80 Td (IO ) Tj ET Q q 0 0 0 rg BT 65.04 423.80 Td (compounds ) Tj ET Q q 0 0 0 rg BT 113.17 423.80 Td (may ) Tj ET Q q 0 0 0 rg BT 132.42 423.80 Td (pr) Tj ET Q q 0 0 0 rg BT 140.94 423.80 Td (ove ) Tj ET Q q 0 0 0 rg BT 157.40 423.80 Td (to ) Tj ET Q q 0 0 0 rg BT 167.76 423.80 Td (be ) Tj ET Q q 0 0 0 rg BT 179.78 423.80 Td (effective ) Tj ET Q q 0 0 0 rg BT 215.67 423.80 Td (or ) Tj ET Q q 0 0 0 rg BT 227.15 423.80 Td (as ) Tj ET Q q 0 0 0 rg BT 238.63 423.80 Td (effective ) Tj ET Q q 0 0 0 rg BT 274.52 423.80 Td (as ) Tj ET Q q 0 0 0 rg BT 285.99 423.80 Td (other ) Tj ET Q q 0 0 0 rg BT 309.69 423.80 Td (competing ) Tj ET Q q 0 0 0 rg BT 353.93 423.80 Td (compounds, ) Tj ET Q q 0 0 0 rg BT 404.56 423.80 Td (or ) Tj ET Q q 0 0 0 rg BT 416.04 423.80 Td (even ) Tj ET Q q 0 0 0 rg BT 436.94 423.80 Td (if ) Tj ET Q q 0 0 0 rg BT 445.08 423.80 Td (appr) Tj ET Q q 0 0 0 rg BT 463.60 423.80 Td (oved, ) Tj ET Q q 0 0 0 rg BT 487.56 423.80 Td (that ) Tj ET Q q 0 0 0 rg BT 505.70 423.80 Td (any ) Tj ET Q q 0 0 0 rg BT 522.73 423.80 Td (of ) Tj ET Q q 0 0 0 rg BT 533.09 423.80 Td (our ) Tj ET Q q 0 0 0 rg BT 549.56 423.80 Td (key ) Tj ET Q q 0 0 0 rg BT 565.46 423.80 Td (IO ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 411.80 Td (compounds ) Tj ET Q q 0 0 0 rg BT 84.05 411.80 Td (will ) Tj ET Q q 0 0 0 rg BT 101.56 411.80 Td (become ) Tj ET Q q 0 0 0 rg BT 134.59 411.80 Td (commer) Tj ET Q q 0 0 0 rg BT 166.43 411.80 Td (cially ) Tj ET Q q 0 0 0 rg BT 191.15 411.80 Td (successful ) Tj ET Q q 0 0 0 rg BT 234.19 411.80 Td (for ) Tj ET Q q 0 0 0 rg BT 248.36 411.80 Td (all ) Tj ET Q q 0 0 0 rg BT 261.42 411.80 Td (appr) Tj ET Q q 0 0 0 rg BT 279.94 411.80 Td (oved ) Tj ET Q q 0 0 0 rg BT 301.32 411.80 Td (indications.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 387.80 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 387.80 Td (e ) Tj ET Q q 0 0 0 rg BT 51.09 387.80 Td (depend ) Tj ET Q q 0 0 0 rg BT 83.03 387.80 Td (on ) Tj ET Q q 0 0 0 rg BT 96.09 387.80 Td (several ) Tj ET Q q 0 0 0 rg BT 127.46 387.80 Td (key ) Tj ET Q q 0 0 0 rg BT 143.84 387.80 Td (products ) Tj ET Q q 0 0 0 rg BT 181.90 387.80 Td (for ) Tj ET Q q 0 0 0 rg BT 196.63 387.80 Td (most ) Tj ET Q q 0 0 0 rg BT 218.57 387.80 Td (of ) Tj ET Q q 0 0 0 rg BT 229.40 387.80 Td (our ) Tj ET Q q 0 0 0 rg BT 246.36 387.80 Td (revenues, ) Tj ET Q q 0 0 0 rg BT 288.02 387.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 309.41 387.80 Td (flows ) Tj ET Q q 0 0 0 rg BT 333.58 387.80 Td (and ) Tj ET Q q 0 0 0 rg BT 351.64 387.80 Td (earnings.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 375.80 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 375.80 Td (e ) Tj ET Q q 0 0 0 rg BT 50.42 375.80 Td (derive ) Tj ET Q q 0 0 0 rg BT 77.98 375.80 Td (a ) Tj ET Q q 0 0 0 rg BT 85.56 375.80 Td (majority ) Tj ET Q q 0 0 0 rg BT 122.02 375.80 Td (of ) Tj ET Q q 0 0 0 rg BT 132.37 375.80 Td (our ) Tj ET Q q 0 0 0 rg BT 148.83 375.80 Td (r) Tj ET Q q 0 0 0 rg BT 152.35 375.80 Td (evenue ) Tj ET Q q 0 0 0 rg BT 182.68 375.80 Td (and ) Tj ET Q q 0 0 0 rg BT 200.25 375.80 Td (earnings ) Tj ET Q q 0 0 0 rg BT 237.83 375.80 Td (fr) Tj ET Q q 0 0 0 rg BT 244.13 375.80 Td (om ) Tj ET Q q 0 0 0 rg BT 258.92 375.80 Td (several ) Tj ET Q q 0 0 0 rg BT 290.37 375.80 Td (key ) Tj ET Q q 0 0 0 rg BT 306.26 375.80 Td (pr) Tj ET Q q 0 0 0 rg BT 314.78 375.80 Td (oducts. ) Tj ET Q q 0 0 0 rg BT 345.96 375.80 Td (Our ) Tj ET Q q 0 0 0 rg BT 364.65 375.80 Td (six ) Tj ET Q q 0 0 0 rg BT 378.33 375.80 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 423.13 375.80 Td (brands ) Tj ET Q q 0 0 0 rg BT 453.49 375.80 Td (comprised ) Tj ET Q q 0 0 0 rg BT 497.72 375.80 Td (appr) Tj ET Q q 0 0 0 rg BT 516.24 375.80 Td (oximately ) Tj ET Q q 0 0 0 rg BT 557.68 375.80 Td (75% ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 363.80 Td (of ) Tj ET Q q 0 0 0 rg BT 46.22 363.80 Td (r) Tj ET Q q 0 0 0 rg BT 49.75 363.80 Td (evenues ) Tj ET Q q 0 0 0 rg BT 83.84 363.80 Td (in ) Tj ET Q q 0 0 0 rg BT 94.06 363.80 Td (2017. ) Tj ET Q q 0 0 0 rg BT 119.01 363.80 Td (Gr) Tj ET Q q 0 0 0 rg BT 129.75 363.80 Td (owth ) Tj ET Q q 0 0 0 rg BT 151.64 363.80 Td (pr) Tj ET Q q 0 0 0 rg BT 160.17 363.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 188.72 363.80 Td (such ) Tj ET Q q 0 0 0 rg BT 209.50 363.80 Td (as ) Tj ET Q q 0 0 0 rg BT 220.83 363.80 Td (Opdivo ) Tj ET Q q 0 0 0 rg BT 252.72 363.80 Td (and ) Tj ET Q q 0 0 0 rg BT 270.17 363.80 Td (Eliquis ) Tj ET Q q 0 0 0 rg BT 300.95 363.80 Td (r) Tj ET Q q 0 0 0 rg BT 304.47 363.80 Td (epr) Tj ET Q q 0 0 0 rg BT 317.43 363.80 Td (esented, ) Tj ET Q q 0 0 0 rg BT 352.36 363.80 Td (and ) Tj ET Q q 0 0 0 rg BT 369.80 363.80 Td (ar) Tj ET Q q 0 0 0 rg BT 378.32 363.80 Td (e ) Tj ET Q q 0 0 0 rg BT 385.21 363.80 Td (expected ) Tj ET Q q 0 0 0 rg BT 422.63 363.80 Td (to ) Tj ET Q q 0 0 0 rg BT 432.85 363.80 Td (incr) Tj ET Q q 0 0 0 rg BT 448.59 363.80 Td (easingly ) Tj ET Q q 0 0 0 rg BT 484.36 363.80 Td (r) Tj ET Q q 0 0 0 rg BT 487.88 363.80 Td (epr) Tj ET Q q 0 0 0 rg BT 500.84 363.80 Td (esent, ) Tj ET Q q 0 0 0 rg BT 526.33 363.80 Td (a ) Tj ET Q q 0 0 0 rg BT 533.78 363.80 Td (significant ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 351.80 Td (part ) Tj ET Q q 0 0 0 rg BT 55.56 351.80 Td (of ) Tj ET Q q 0 0 0 rg BT 66.22 351.80 Td (our ) Tj ET Q q 0 0 0 rg BT 83.00 351.80 Td (r) Tj ET Q q 0 0 0 rg BT 86.52 351.80 Td (evenue, ) Tj ET Q q 0 0 0 rg BT 119.67 351.80 Td (earnings ) Tj ET Q q 0 0 0 rg BT 157.56 351.80 Td (and ) Tj ET Q q 0 0 0 rg BT 175.44 351.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 196.66 351.80 Td (flows. ) Tj ET Q q 0 0 0 rg BT 222.96 351.80 Td (A) Tj ET Q q 0 0 0 rg BT 228.89 351.80 Td ( ) Tj ET Q q 0 0 0 rg BT 231.78 351.80 Td (r) Tj ET Q q 0 0 0 rg BT 235.30 351.80 Td (eduction ) Tj ET Q q 0 0 0 rg BT 272.62 351.80 Td (in ) Tj ET Q q 0 0 0 rg BT 283.28 351.80 Td (r) Tj ET Q q 0 0 0 rg BT 286.80 351.80 Td (evenue ) Tj ET Q q 0 0 0 rg BT 317.45 351.80 Td (fr) Tj ET Q q 0 0 0 rg BT 323.75 351.80 Td (om ) Tj ET Q q 0 0 0 rg BT 338.86 351.80 Td (any ) Tj ET Q q 0 0 0 rg BT 356.18 351.80 Td (of ) Tj ET Q q 0 0 0 rg BT 366.85 351.80 Td (these ) Tj ET Q q 0 0 0 rg BT 390.28 351.80 Td (pr) Tj ET Q q 0 0 0 rg BT 398.80 351.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 427.80 351.80 Td (could ) Tj ET Q q 0 0 0 rg BT 452.91 351.80 Td (adversely ) Tj ET Q q 0 0 0 rg BT 494.11 351.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 524.21 351.80 Td (our ) Tj ET Q q 0 0 0 rg BT 540.99 351.80 Td (earnings ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 339.80 Td (and ) Tj ET Q q 0 0 0 rg BT 53.24 339.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 73.82 339.80 Td (flows. ) Tj ET Q q 0 0 0 rg BT 99.52 339.80 Td (Also, ) Tj ET Q q 0 0 0 rg BT 122.04 339.80 Td (if ) Tj ET Q q 0 0 0 rg BT 129.84 339.80 Td (one ) Tj ET Q q 0 0 0 rg BT 146.52 339.80 Td (of ) Tj ET Q q 0 0 0 rg BT 156.54 339.80 Td (our ) Tj ET Q q 0 0 0 rg BT 172.68 339.80 Td (major ) Tj ET Q q 0 0 0 rg BT 198.81 339.80 Td (pr) Tj ET Q q 0 0 0 rg BT 207.33 339.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 235.69 339.80 Td (wer) Tj ET Q q 0 0 0 rg BT 250.32 339.80 Td (e ) Tj ET Q q 0 0 0 rg BT 257.00 339.80 Td (to ) Tj ET Q q 0 0 0 rg BT 267.02 339.80 Td (become ) Tj ET Q q 0 0 0 rg BT 299.80 339.80 Td (subject ) Tj ET Q q 0 0 0 rg BT 330.37 339.80 Td (to ) Tj ET Q q 0 0 0 rg BT 340.39 339.80 Td (issues ) Tj ET Q q 0 0 0 rg BT 366.53 339.80 Td (such ) Tj ET Q q 0 0 0 rg BT 387.10 339.80 Td (as ) Tj ET Q q 0 0 0 rg BT 398.24 339.80 Td (loss ) Tj ET Q q 0 0 0 rg BT 416.04 339.80 Td (of ) Tj ET Q q 0 0 0 rg BT 426.06 339.80 Td (patent ) Tj ET Q q 0 0 0 rg BT 453.30 339.80 Td (pr) Tj ET Q q 0 0 0 rg BT 461.82 339.80 Td (otection, ) Tj ET Q q 0 0 0 rg BT 498.78 339.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 543.24 339.80 Td (changes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 327.80 Td (in ) Tj ET Q q 0 0 0 rg BT 46.40 327.80 Td (demand, ) Tj ET Q q 0 0 0 rg BT 83.18 327.80 Td (formulary ) Tj ET Q q 0 0 0 rg BT 125.80 327.80 Td (access ) Tj ET Q q 0 0 0 rg BT 154.52 327.80 Td (changes, ) Tj ET Q q 0 0 0 rg BT 192.40 327.80 Td (material ) Tj ET Q q 0 0 0 rg BT 228.91 327.80 Td (pr) Tj ET Q q 0 0 0 rg BT 237.43 327.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 262.27 327.80 Td (liability) Tj ET Q q 0 0 0 rg BT 292.82 327.80 Td (, ) Tj ET Q q 0 0 0 rg BT 297.94 327.80 Td (unexpected ) Tj ET Q q 0 0 0 rg BT 345.53 327.80 Td (side ) Tj ET Q q 0 0 0 rg BT 364.26 327.80 Td (effects, ) Tj ET Q q 0 0 0 rg BT 394.92 327.80 Td (r) Tj ET Q q 0 0 0 rg BT 398.44 327.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 439.39 327.80 Td (pr) Tj ET Q q 0 0 0 rg BT 447.91 327.80 Td (oceedings, ) Tj ET Q q 0 0 0 rg BT 493.01 327.80 Td (negative ) Tj ET Q q 0 0 0 rg BT 529.51 327.80 Td (publicity ) Tj ET Q q 0 0 0 rg BT 567.12 327.80 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 315.80 Td (a ) Tj ET Q q 0 0 0 rg BT 42.43 315.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 86.09 315.80 Td (advancement ) Tj ET Q q 0 0 0 rg BT 140.27 315.80 Td (of ) Tj ET Q q 0 0 0 rg BT 149.48 315.80 Td (competing ) Tj ET Q q 0 0 0 rg BT 192.57 315.80 Td (pr) Tj ET Q q 0 0 0 rg BT 201.09 315.80 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 231.13 315.80 Td (we ) Tj ET Q q 0 0 0 rg BT 243.67 315.80 Td (may ) Tj ET Q q 0 0 0 rg BT 261.76 315.80 Td (incur ) Tj ET Q q 0 0 0 rg BT 284.30 315.80 Td (an ) Tj ET Q q 0 0 0 rg BT 295.74 315.80 Td (adverse ) Tj ET Q q 0 0 0 rg BT 328.27 315.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 356.92 315.80 Td (on ) Tj ET Q q 0 0 0 rg BT 368.35 315.80 Td (our ) Tj ET Q q 0 0 0 rg BT 383.67 315.80 Td (business, ) Tj ET Q q 0 0 0 rg BT 421.50 315.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 458.48 315.80 Td (condition, ) Tj ET Q q 0 0 0 rg BT 500.19 315.80 Td (r) Tj ET Q q 0 0 0 rg BT 503.71 315.80 Td (esults ) Tj ET Q q 0 0 0 rg BT 527.92 315.80 Td (of ) Tj ET Q q 0 0 0 rg BT 537.13 315.80 Td (operation ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 303.80 Td (or ) Tj ET Q q 0 0 0 rg BT 47.39 303.80 Td (trading ) Tj ET Q q 0 0 0 rg BT 79.34 303.80 Td (price ) Tj ET Q q 0 0 0 rg BT 102.39 303.80 Td (of ) Tj ET Q q 0 0 0 rg BT 112.67 303.80 Td (our ) Tj ET Q q 0 0 0 rg BT 129.06 303.80 Td (stock. ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 279.80 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 279.80 Td (e ) Tj ET Q q 0 0 0 rg BT 51.09 279.80 Td (may ) Tj ET Q q 0 0 0 rg BT 70.80 279.80 Td (experience ) Tj ET Q q 0 0 0 rg BT 117.73 279.80 Td (dif) Tj ET Q q 0 0 0 rg BT 128.66 279.80 Td (ficulties ) Tj ET Q q 0 0 0 rg BT 163.93 279.80 Td (or ) Tj ET Q q 0 0 0 rg BT 175.32 279.80 Td (delays ) Tj ET Q q 0 0 0 rg BT 203.37 279.80 Td (in ) Tj ET Q q 0 0 0 rg BT 214.21 279.80 Td (the ) Tj ET Q q 0 0 0 rg BT 229.49 279.80 Td (development ) Tj ET Q q 0 0 0 rg BT 283.64 279.80 Td (and ) Tj ET Q q 0 0 0 rg BT 301.70 279.80 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 380.31 279.80 Td (of ) Tj ET Q q 0 0 0 rg BT 391.14 279.80 Td (new ) Tj ET Q q 0 0 0 rg BT 410.31 279.80 Td (products.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 267.80 Td (Compounds ) Tj ET Q q 0 0 0 rg BT 86.27 267.80 Td (or ) Tj ET Q q 0 0 0 rg BT 97.66 267.80 Td (pr) Tj ET Q q 0 0 0 rg BT 106.18 267.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 134.77 267.80 Td (may ) Tj ET Q q 0 0 0 rg BT 153.92 267.80 Td (appear ) Tj ET Q q 0 0 0 rg BT 184.75 267.80 Td (pr) Tj ET Q q 0 0 0 rg BT 193.27 267.80 Td (omising ) Tj ET Q q 0 0 0 rg BT 227.43 267.80 Td (in ) Tj ET Q q 0 0 0 rg BT 237.69 267.80 Td (development ) Tj ET Q q 0 0 0 rg BT 290.72 267.80 Td (but ) Tj ET Q q 0 0 0 rg BT 305.99 267.80 Td (fail ) Tj ET Q q 0 0 0 rg BT 321.81 267.80 Td (to ) Tj ET Q q 0 0 0 rg BT 332.08 267.80 Td (r) Tj ET Q q 0 0 0 rg BT 335.60 267.80 Td (each ) Tj ET Q q 0 0 0 rg BT 356.97 267.80 Td (market ) Tj ET Q q 0 0 0 rg BT 387.23 267.80 Td (within ) Tj ET Q q 0 0 0 rg BT 414.72 267.80 Td (the ) Tj ET Q q 0 0 0 rg BT 429.43 267.80 Td (expected ) Tj ET Q q 0 0 0 rg BT 466.89 267.80 Td (or ) Tj ET Q q 0 0 0 rg BT 478.27 267.80 Td (optimal ) Tj ET Q q 0 0 0 rg BT 511.32 267.80 Td (timeframe, ) Tj ET Q q 0 0 0 rg BT 556.85 267.80 Td (or ) Tj ET Q q 0 0 0 rg BT 568.24 267.80 Td (at ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 255.80 Td (all. ) Tj ET Q q 0 0 0 rg BT 51.10 255.80 Td (In ) Tj ET Q q 0 0 0 rg BT 61.47 255.80 Td (addition, ) Tj ET Q q 0 0 0 rg BT 99.34 255.80 Td (pr) Tj ET Q q 0 0 0 rg BT 107.87 255.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 132.12 255.80 Td (extensions ) Tj ET Q q 0 0 0 rg BT 175.82 255.80 Td (or ) Tj ET Q q 0 0 0 rg BT 186.75 255.80 Td (additional ) Tj ET Q q 0 0 0 rg BT 229.91 255.80 Td (indications ) Tj ET Q q 0 0 0 rg BT 276.39 255.80 Td (may ) Tj ET Q q 0 0 0 rg BT 295.09 255.80 Td (not ) Tj ET Q q 0 0 0 rg BT 309.91 255.80 Td (be ) Tj ET Q q 0 0 0 rg BT 321.39 255.80 Td (appr) Tj ET Q q 0 0 0 rg BT 339.91 255.80 Td (oved. ) Tj ET Q q 0 0 0 rg BT 363.33 255.80 Td (Furthermor) Tj ET Q q 0 0 0 rg BT 410.18 255.80 Td (e, ) Tj ET Q q 0 0 0 rg BT 419.16 255.80 Td (pr) Tj ET Q q 0 0 0 rg BT 427.68 255.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 455.83 255.80 Td (or ) Tj ET Q q 0 0 0 rg BT 466.76 255.80 Td (indications ) Tj ET Q q 0 0 0 rg BT 513.25 255.80 Td (appr) Tj ET Q q 0 0 0 rg BT 531.77 255.80 Td (oved ) Tj ET Q q 0 0 0 rg BT 552.68 255.80 Td (under ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 243.80 Td (the ) Tj ET Q q 0 0 0 rg BT 50.91 243.80 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 70.82 243.80 Td (FDA's ) Tj ET Q q 0 0 0 rg BT 98.79 243.80 Td (Accelerated ) Tj ET Q q 0 0 0 rg BT 149.04 243.80 Td (Appr) Tj ET Q q 0 0 0 rg BT 168.67 243.80 Td (oval ) Tj ET Q q 0 0 0 rg BT 188.58 243.80 Td (Pr) Tj ET Q q 0 0 0 rg BT 198.21 243.80 Td (ogram ) Tj ET Q q 0 0 0 rg BT 227.01 243.80 Td (may ) Tj ET Q q 0 0 0 rg BT 246.36 243.80 Td (be ) Tj ET Q q 0 0 0 rg BT 258.50 243.80 Td (contingent ) Tj ET Q q 0 0 0 rg BT 303.40 243.80 Td (upon ) Tj ET Q q 0 0 0 rg BT 326.09 243.80 Td (verification ) Tj ET Q q 0 0 0 rg BT 374.89 243.80 Td (and ) Tj ET Q q 0 0 0 rg BT 392.58 243.80 Td (description ) Tj ET Q q 0 0 0 rg BT 440.27 243.80 Td (of ) Tj ET Q q 0 0 0 rg BT 450.74 243.80 Td (clinical ) Tj ET Q q 0 0 0 rg BT 483.42 243.80 Td (benefit ) Tj ET Q q 0 0 0 rg BT 513.33 243.80 Td (in ) Tj ET Q q 0 0 0 rg BT 523.80 243.80 Td (confirmatory ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 231.80 Td (studies ) Tj ET Q q 0 0 0 rg BT 65.50 231.80 Td (and ) Tj ET Q q 0 0 0 rg BT 82.21 231.80 Td (such ) Tj ET Q q 0 0 0 rg BT 102.26 231.80 Td (studies ) Tj ET Q q 0 0 0 rg BT 131.76 231.80 Td (may ) Tj ET Q q 0 0 0 rg BT 150.14 231.80 Td (not ) Tj ET Q q 0 0 0 rg BT 164.63 231.80 Td (be ) Tj ET Q q 0 0 0 rg BT 175.79 231.80 Td (successful. ) Tj ET Q q 0 0 0 rg BT 220.55 231.80 Td (For ) Tj ET Q q 0 0 0 rg BT 237.27 231.80 Td (example, ) Tj ET Q q 0 0 0 rg BT 274.80 231.80 Td (when ) Tj ET Q q 0 0 0 rg BT 297.63 231.80 Td (we ) Tj ET Q q 0 0 0 rg BT 310.46 231.80 Td (announced ) Tj ET Q q 0 0 0 rg BT 356.05 231.80 Td (we ) Tj ET Q q 0 0 0 rg BT 368.88 231.80 Td (would ) Tj ET Q q 0 0 0 rg BT 395.04 231.80 Td (not ) Tj ET Q q 0 0 0 rg BT 409.54 231.80 Td (pursue ) Tj ET Q q 0 0 0 rg BT 438.48 231.80 Td (an ) Tj ET Q q 0 0 0 rg BT 450.20 231.80 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 498.55 231.80 Td (r) Tj ET Q q 0 0 0 rg BT 502.08 231.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 542.12 231.80 Td (pathway ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 219.80 Td (for ) Tj ET Q q 0 0 0 rg BT 51.01 219.80 Td (the ) Tj ET Q q 0 0 0 rg BT 66.57 219.80 Td (combination ) Tj ET Q q 0 0 0 rg BT 119.91 219.80 Td (of ) Tj ET Q q 0 0 0 rg BT 131.03 219.80 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 171.86 219.80 Td (ervoy ) Tj ET Q q 0 0 0 rg BT 197.40 219.80 Td (in ) Tj ET Q q 0 0 0 rg BT 208.52 219.80 Td (lung ) Tj ET Q q 0 0 0 rg BT 229.64 219.80 Td (cancer ) Tj ET Q q 0 0 0 rg BT 260.19 219.80 Td (and ) Tj ET Q q 0 0 0 rg BT 278.53 219.80 Td (when ) Tj ET Q q 0 0 0 rg BT 302.98 219.80 Td (we ) Tj ET Q q 0 0 0 rg BT 317.43 219.80 Td (r) Tj ET Q q 0 0 0 rg BT 320.95 219.80 Td (eported ) Tj ET Q q 0 0 0 rg BT 354.84 219.80 Td (negative ) Tj ET Q q 0 0 0 rg BT 392.05 219.80 Td (r) Tj ET Q q 0 0 0 rg BT 395.57 219.80 Td (esults ) Tj ET Q q 0 0 0 rg BT 421.69 219.80 Td (fr) Tj ET Q q 0 0 0 rg BT 427.99 219.80 Td (om ) Tj ET Q q 0 0 0 rg BT 443.56 219.80 Td (CheckMate-026, ) Tj ET Q q 0 0 0 rg BT 513.26 219.80 Td (we ) Tj ET Q q 0 0 0 rg BT 527.71 219.80 Td (experienced ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 207.80 Td (negative ) Tj ET Q q 0 0 0 rg BT 72.36 207.80 Td (impacts ) Tj ET Q q 0 0 0 rg BT 105.96 207.80 Td (on ) Tj ET Q q 0 0 0 rg BT 118.45 207.80 Td (our ) Tj ET Q q 0 0 0 rg BT 134.83 207.80 Td (stock ) Tj ET Q q 0 0 0 rg BT 157.87 207.80 Td (price ) Tj ET Q q 0 0 0 rg BT 180.91 207.80 Td (in ) Tj ET Q q 0 0 0 rg BT 191.18 207.80 Td (2016. ) Tj ET Q q 0 0 0 rg BT 216.17 207.80 Td (Developing ) Tj ET Q q 0 0 0 rg BT 264.75 207.80 Td (and ) Tj ET Q q 0 0 0 rg BT 282.24 207.80 Td (commer) Tj ET Q q 0 0 0 rg BT 314.08 207.80 Td (cializing ) Tj ET Q q 0 0 0 rg BT 351.01 207.80 Td (new ) Tj ET Q q 0 0 0 rg BT 369.61 207.80 Td (compounds ) Tj ET Q q 0 0 0 rg BT 417.66 207.80 Td (and ) Tj ET Q q 0 0 0 rg BT 435.15 207.80 Td (pr) Tj ET Q q 0 0 0 rg BT 443.67 207.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 472.26 207.80 Td (include ) Tj ET Q q 0 0 0 rg BT 504.19 207.80 Td (inher) Tj ET Q q 0 0 0 rg BT 524.93 207.80 Td (ent ) Tj ET Q q 0 0 0 rg BT 539.63 207.80 Td (risks ) Tj ET Q q 0 0 0 rg BT 561.01 207.80 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 195.80 Td (uncertainties, ) Tj ET Q q 0 0 0 rg BT 94.41 195.80 Td (including ) Tj ET Q q 0 0 0 rg BT 135.88 195.80 Td (\(i\) ) Tj ET Q q 0 0 0 rg BT 149.01 195.80 Td (due ) Tj ET Q q 0 0 0 rg BT 167.14 195.80 Td (to ) Tj ET Q q 0 0 0 rg BT 178.62 195.80 Td (efficacy ) Tj ET Q q 0 0 0 rg BT 213.40 195.80 Td (and ) Tj ET Q q 0 0 0 rg BT 232.10 195.80 Td (safety ) Tj ET Q q 0 0 0 rg BT 259.12 195.80 Td (concerns, ) Tj ET Q q 0 0 0 rg BT 301.41 195.80 Td (delayed ) Tj ET Q q 0 0 0 rg BT 336.20 195.80 Td (or ) Tj ET Q q 0 0 0 rg BT 348.79 195.80 Td (denied ) Tj ET Q q 0 0 0 rg BT 379.14 195.80 Td (r) Tj ET Q q 0 0 0 rg BT 382.66 195.80 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 424.68 195.80 Td (appr) Tj ET Q q 0 0 0 rg BT 443.20 195.80 Td (ovals, ) Tj ET Q q 0 0 0 rg BT 470.50 195.80 Td (delays ) Tj ET Q q 0 0 0 rg BT 499.75 195.80 Td (or ) Tj ET Q q 0 0 0 rg BT 512.33 195.80 Td (challenges ) Tj ET Q q 0 0 0 rg BT 558.79 195.80 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 183.80 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 183.80 Td (oducing ) Tj ET Q q 0 0 0 rg BT 78.49 183.80 Td (pr) Tj ET Q q 0 0 0 rg BT 87.01 183.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 114.88 183.80 Td (on ) Tj ET Q q 0 0 0 rg BT 126.63 183.80 Td (a ) Tj ET Q q 0 0 0 rg BT 133.39 183.80 Td (commer) Tj ET Q q 0 0 0 rg BT 165.23 183.80 Td (cial ) Tj ET Q q 0 0 0 rg BT 181.98 183.80 Td (scale ) Tj ET Q q 0 0 0 rg BT 204.28 183.80 Td (or ) Tj ET Q q 0 0 0 rg BT 214.93 183.80 Td (excessive ) Tj ET Q q 0 0 0 rg BT 253.88 183.80 Td (costs ) Tj ET Q q 0 0 0 rg BT 275.63 183.80 Td (to ) Tj ET Q q 0 0 0 rg BT 285.17 183.80 Td (manufactur) Tj ET Q q 0 0 0 rg BT 330.90 183.80 Td (e ) Tj ET Q q 0 0 0 rg BT 337.10 183.80 Td (them; ) Tj ET Q q 0 0 0 rg BT 361.62 183.80 Td (\(ii\) failur) Tj ET Q q 0 0 0 rg BT 398.19 183.80 Td (e ) Tj ET Q q 0 0 0 rg BT 404.39 183.80 Td (to ) Tj ET Q q 0 0 0 rg BT 413.92 183.80 Td (enter ) Tj ET Q q 0 0 0 rg BT 436.22 183.80 Td (into ) Tj ET Q q 0 0 0 rg BT 453.53 183.80 Td (or ) Tj ET Q q 0 0 0 rg BT 464.18 183.80 Td (implement ) Tj ET Q q 0 0 0 rg BT 507.59 183.80 Td (optimal ) Tj ET Q q 0 0 0 rg BT 539.90 183.80 Td (alliances ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 171.80 Td (for ) Tj ET Q q 0 0 0 rg BT 49.84 171.80 Td (the ) Tj ET Q q 0 0 0 rg BT 64.23 171.80 Td (development ) Tj ET Q q 0 0 0 rg BT 116.93 171.80 Td (and/or ) Tj ET Q q 0 0 0 rg BT 145.77 171.80 Td (commer) Tj ET Q q 0 0 0 rg BT 177.61 171.80 Td (cialization ) Tj ET Q q 0 0 0 rg BT 222.00 171.80 Td (of ) Tj ET Q q 0 0 0 rg BT 231.95 171.80 Td (new ) Tj ET Q q 0 0 0 rg BT 250.23 171.80 Td (pr) Tj ET Q q 0 0 0 rg BT 258.75 171.80 Td (oducts; ) Tj ET Q q 0 0 0 rg BT 290.36 171.80 Td (\(iii\) failur) Tj ET Q q 0 0 0 rg BT 329.71 171.80 Td (e ) Tj ET Q q 0 0 0 rg BT 336.32 171.80 Td (to ) Tj ET Q q 0 0 0 rg BT 346.27 171.80 Td (maintain ) Tj ET Q q 0 0 0 rg BT 384.00 171.80 Td (a ) Tj ET Q q 0 0 0 rg BT 391.17 171.80 Td (consistent ) Tj ET Q q 0 0 0 rg BT 433.33 171.80 Td (scope ) Tj ET Q q 0 0 0 rg BT 458.27 171.80 Td (and ) Tj ET Q q 0 0 0 rg BT 475.44 171.80 Td (variety ) Tj ET Q q 0 0 0 rg BT 505.38 171.80 Td (of ) Tj ET Q q 0 0 0 rg BT 515.32 171.80 Td (pr) Tj ET Q q 0 0 0 rg BT 523.84 171.80 Td (omising ) Tj ET Q q 0 0 0 rg BT 557.68 171.80 Td (late-) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 159.80 Td (stage ) Tj ET Q q 0 0 0 rg BT 59.93 159.80 Td (pr) Tj ET Q q 0 0 0 rg BT 68.45 159.80 Td (oducts; ) Tj ET Q q 0 0 0 rg BT 100.72 159.80 Td (\(iv\) failur) Tj ET Q q 0 0 0 rg BT 138.95 159.80 Td (e ) Tj ET Q q 0 0 0 rg BT 146.21 159.80 Td (of ) Tj ET Q q 0 0 0 rg BT 156.82 159.80 Td (one ) Tj ET Q q 0 0 0 rg BT 174.08 159.80 Td (or ) Tj ET Q q 0 0 0 rg BT 185.79 159.80 Td (mor) Tj ET Q q 0 0 0 rg BT 201.54 159.80 Td (e ) Tj ET Q q 0 0 0 rg BT 208.80 159.80 Td (of ) Tj ET Q q 0 0 0 rg BT 219.40 159.80 Td (our ) Tj ET Q q 0 0 0 rg BT 236.12 159.80 Td (pr) Tj ET Q q 0 0 0 rg BT 244.64 159.80 Td (oducts ) Tj ET Q q 0 0 0 rg BT 273.57 159.80 Td (to ) Tj ET Q q 0 0 0 rg BT 284.18 159.80 Td (achieve ) Tj ET Q q 0 0 0 rg BT 317.53 159.80 Td (or ) Tj ET Q q 0 0 0 rg BT 329.25 159.80 Td (maintain ) Tj ET Q q 0 0 0 rg BT 367.63 159.80 Td (commer) Tj ET Q q 0 0 0 rg BT 399.47 159.80 Td (cial ) Tj ET Q q 0 0 0 rg BT 417.29 159.80 Td (viability; ) Tj ET Q q 0 0 0 rg BT 456.21 159.80 Td (and ) Tj ET Q q 0 0 0 rg BT 474.04 159.80 Td (\(v\) ) Tj ET Q q 0 0 0 rg BT 487.96 159.80 Td (changes ) Tj ET Q q 0 0 0 rg BT 523.56 159.80 Td (in ) Tj ET Q q 0 0 0 rg BT 534.16 159.80 Td (r) Tj ET Q q 0 0 0 rg BT 537.68 159.80 Td (egulatory ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 147.80 Td (appr) Tj ET Q q 0 0 0 rg BT 54.52 147.80 Td (oval ) Tj ET Q q 0 0 0 rg BT 74.24 147.80 Td (pr) Tj ET Q q 0 0 0 rg BT 82.76 147.80 Td (ocesses ) Tj ET Q q 0 0 0 rg BT 115.25 147.80 Td (may ) Tj ET Q q 0 0 0 rg BT 134.41 147.80 Td (cause ) Tj ET Q q 0 0 0 rg BT 159.68 147.80 Td (delays ) Tj ET Q q 0 0 0 rg BT 187.72 147.80 Td (or ) Tj ET Q q 0 0 0 rg BT 199.12 147.80 Td (denials ) Tj ET Q q 0 0 0 rg BT 230.50 147.80 Td (of ) Tj ET Q q 0 0 0 rg BT 240.78 147.80 Td (new ) Tj ET Q q 0 0 0 rg BT 259.39 147.80 Td (pr) Tj ET Q q 0 0 0 rg BT 267.91 147.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 292.63 147.80 Td (appr) Tj ET Q q 0 0 0 rg BT 311.15 147.80 Td (ovals.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 123.80 Td (Regulatory ) Tj ET Q q 0 0 0 rg BT 83.32 123.80 Td (appr) Tj ET Q q 0 0 0 rg BT 101.84 123.80 Td (oval ) Tj ET Q q 0 0 0 rg BT 121.94 123.80 Td (delays ) Tj ET Q q 0 0 0 rg BT 150.38 123.80 Td (ar) Tj ET Q q 0 0 0 rg BT 158.90 123.80 Td (e ) Tj ET Q q 0 0 0 rg BT 166.22 123.80 Td (especially ) Tj ET Q q 0 0 0 rg BT 209.09 123.80 Td (common ) Tj ET Q q 0 0 0 rg BT 245.85 123.80 Td (when ) Tj ET Q q 0 0 0 rg BT 269.85 123.80 Td (a ) Tj ET Q q 0 0 0 rg BT 277.73 123.80 Td (pr) Tj ET Q q 0 0 0 rg BT 286.25 123.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 311.36 123.80 Td (is ) Tj ET Q q 0 0 0 rg BT 320.91 123.80 Td (expected ) Tj ET Q q 0 0 0 rg BT 358.77 123.80 Td (to ) Tj ET Q q 0 0 0 rg BT 369.43 123.80 Td (have ) Tj ET Q q 0 0 0 rg BT 391.20 123.80 Td (a ) Tj ET Q q 0 0 0 rg BT 399.08 123.80 Td (Risk ) Tj ET Q q 0 0 0 rg BT 419.18 123.80 Td (Evaluation ) Tj ET Q q 0 0 0 rg BT 465.95 123.80 Td (and ) Tj ET Q q 0 0 0 rg BT 483.84 123.80 Td (Mitigation ) Tj ET Q q 0 0 0 rg BT 528.94 123.80 Td (Strategy) Tj ET Q q 0 0 0 rg BT 561.72 123.80 Td (, ) Tj ET Q q 0 0 0 rg BT 567.10 123.80 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 111.80 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 111.80 Td (equir) Tj ET Q q 0 0 0 rg BT 60.26 111.80 Td (ed ) Tj ET Q q 0 0 0 rg BT 72.72 111.80 Td (by ) Tj ET Q q 0 0 0 rg BT 85.17 111.80 Td (the ) Tj ET Q q 0 0 0 rg BT 100.41 111.80 Td (FDA) Tj ET Q q 0 0 0 rg BT 119.67 111.80 Td ( ) Tj ET Q q 0 0 0 rg BT 122.69 111.80 Td (to ) Tj ET Q q 0 0 0 rg BT 133.49 111.80 Td (addr) Tj ET Q q 0 0 0 rg BT 152.01 111.80 Td (ess ) Tj ET Q q 0 0 0 rg BT 167.25 111.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 212.49 111.80 Td (risk/benefit ) Tj ET Q q 0 0 0 rg BT 260.50 111.80 Td (issues. ) Tj ET Q q 0 0 0 rg BT 289.91 111.80 Td (The ) Tj ET Q q 0 0 0 rg BT 307.93 111.80 Td (inability ) Tj ET Q q 0 0 0 rg BT 344.28 111.80 Td (to ) Tj ET Q q 0 0 0 rg BT 355.08 111.80 Td (bring ) Tj ET Q q 0 0 0 rg BT 379.77 111.80 Td (a ) Tj ET Q q 0 0 0 rg BT 387.79 111.80 Td (pr) Tj ET Q q 0 0 0 rg BT 396.31 111.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 421.55 111.80 Td (to ) Tj ET Q q 0 0 0 rg BT 432.35 111.80 Td (market ) Tj ET Q q 0 0 0 rg BT 463.14 111.80 Td (or ) Tj ET Q q 0 0 0 rg BT 475.05 111.80 Td (a ) Tj ET Q q 0 0 0 rg BT 483.07 111.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 528.31 111.80 Td (delay ) Tj ET Q q 0 0 0 rg BT 552.98 111.80 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 111.80 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 99.80 Td (expected ) Tj ET Q q 0 0 0 rg BT 73.58 99.80 Td (appr) Tj ET Q q 0 0 0 rg BT 92.10 99.80 Td (oval ) Tj ET Q q 0 0 0 rg BT 111.92 99.80 Td (and ) Tj ET Q q 0 0 0 rg BT 129.53 99.80 Td (r) Tj ET Q q 0 0 0 rg BT 133.05 99.80 Td (elated ) Tj ET Q q 0 0 0 rg BT 160.09 99.80 Td (launch ) Tj ET Q q 0 0 0 rg BT 189.92 99.80 Td (date ) Tj ET Q q 0 0 0 rg BT 209.74 99.80 Td (of ) Tj ET Q q 0 0 0 rg BT 220.13 99.80 Td (a ) Tj ET Q q 0 0 0 rg BT 227.73 99.80 Td (new ) Tj ET Q q 0 0 0 rg BT 246.45 99.80 Td (pr) Tj ET Q q 0 0 0 rg BT 254.97 99.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 279.79 99.80 Td (could ) Tj ET Q q 0 0 0 rg BT 304.62 99.80 Td (negatively ) Tj ET Q q 0 0 0 rg BT 348.31 99.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 378.14 99.80 Td (our ) Tj ET Q q 0 0 0 rg BT 394.64 99.80 Td (r) Tj ET Q q 0 0 0 rg BT 398.16 99.80 Td (evenues ) Tj ET Q q 0 0 0 rg BT 432.41 99.80 Td (and ) Tj ET Q q 0 0 0 rg BT 450.02 99.80 Td (earnings. ) Tj ET Q q 0 0 0 rg BT 490.13 99.80 Td (In ) Tj ET Q q 0 0 0 rg BT 501.06 99.80 Td (addition, ) Tj ET Q q 0 0 0 rg BT 539.51 99.80 Td (if ) Tj ET Q q 0 0 0 rg BT 547.67 99.80 Td (certain ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 87.80 Td (acquir) Tj ET Q q 0 0 0 rg BT 61.74 87.80 Td (ed ) Tj ET Q q 0 0 0 rg BT 73.57 87.80 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 108.17 87.80 Td (pr) Tj ET Q q 0 0 0 rg BT 116.69 87.80 Td (ograms ) Tj ET Q q 0 0 0 rg BT 149.08 87.80 Td (ar) Tj ET Q q 0 0 0 rg BT 157.60 87.80 Td (e ) Tj ET Q q 0 0 0 rg BT 164.43 87.80 Td (canceled ) Tj ET Q q 0 0 0 rg BT 202.35 87.80 Td (or ) Tj ET Q q 0 0 0 rg BT 213.64 87.80 Td (we ) Tj ET Q q 0 0 0 rg BT 227.14 87.80 Td (believe ) Tj ET Q q 0 0 0 rg BT 257.84 87.80 Td (their ) Tj ET Q q 0 0 0 rg BT 279.11 87.80 Td (commer) Tj ET Q q 0 0 0 rg BT 310.95 87.80 Td (cial ) Tj ET Q q 0 0 0 rg BT 328.34 87.80 Td (pr) Tj ET Q q 0 0 0 rg BT 336.86 87.80 Td (ospects ) Tj ET Q q 0 0 0 rg BT 368.69 87.80 Td (have ) Tj ET Q q 0 0 0 rg BT 389.96 87.80 Td (been ) Tj ET Q q 0 0 0 rg BT 411.22 87.80 Td (r) Tj ET Q q 0 0 0 rg BT 414.74 87.80 Td (educed, ) Tj ET Q q 0 0 0 rg BT 447.95 87.80 Td (we ) Tj ET Q q 0 0 0 rg BT 461.45 87.80 Td (may ) Tj ET Q q 0 0 0 rg BT 480.50 87.80 Td (r) Tj ET Q q 0 0 0 rg BT 484.02 87.80 Td (ecognize ) Tj ET Q q 0 0 0 rg BT 521.39 87.80 Td (material ) Tj ET Q q 0 0 0 rg BT 557.67 87.80 Td (non-) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 75.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 56.03 75.80 Td (impairment ) Tj ET Q q 0 0 0 rg BT 103.84 75.80 Td (char) Tj ET Q q 0 0 0 rg BT 121.80 75.80 Td (ges ) Tj ET Q q 0 0 0 rg BT 136.83 75.80 Td (for ) Tj ET Q q 0 0 0 rg BT 150.20 75.80 Td (those ) Tj ET Q q 0 0 0 rg BT 173.01 75.80 Td (pr) Tj ET Q q 0 0 0 rg BT 181.53 75.80 Td (ograms. ) Tj ET Q q 0 0 0 rg BT 215.74 75.80 Td (Finally) Tj ET Q q 0 0 0 rg BT 244.07 75.80 Td (, ) Tj ET Q q 0 0 0 rg BT 248.27 75.80 Td (losing ) Tj ET Q q 0 0 0 rg BT 274.42 75.80 Td (key ) Tj ET Q q 0 0 0 rg BT 289.43 75.80 Td (molecules ) Tj ET Q q 0 0 0 rg BT 331.12 75.80 Td (and ) Tj ET Q q 0 0 0 rg BT 347.82 75.80 Td (intermediaries ) Tj ET Q q 0 0 0 rg BT 407.84 75.80 Td (or ) Tj ET Q q 0 0 0 rg BT 418.44 75.80 Td (our ) Tj ET Q q 0 0 0 rg BT 434.03 75.80 Td (compound ) Tj ET Q q 0 0 0 rg BT 477.39 75.80 Td (library ) Tj ET Q q 0 0 0 rg BT 506.87 75.80 Td (thr) Tj ET Q q 0 0 0 rg BT 518.17 75.80 Td (ough ) Tj ET Q q 0 0 0 rg BT 539.87 75.80 Td (a ) Tj ET Q q 0 0 0 rg BT 546.57 75.80 Td (natural ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 63.80 Td (or ) Tj ET Q q 0 0 0 rg BT 47.39 63.80 Td (man-made ) Tj ET Q q 0 0 0 rg BT 92.10 63.80 Td (disaster ) Tj ET Q q 0 0 0 rg BT 126.27 63.80 Td (or ) Tj ET Q q 0 0 0 rg BT 137.67 63.80 Td (act ) Tj ET Q q 0 0 0 rg BT 152.38 63.80 Td (of ) Tj ET Q q 0 0 0 rg BT 162.66 63.80 Td (sabotage ) Tj ET Q q 0 0 0 rg BT 201.27 63.80 Td (could ) Tj ET Q q 0 0 0 rg BT 225.99 63.80 Td (negatively ) Tj ET Q q 0 0 0 rg BT 269.57 63.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 299.29 63.80 Td (the ) Tj ET Q q 0 0 0 rg BT 314.01 63.80 Td (pr) Tj ET Q q 0 0 0 rg BT 322.53 63.80 Td (oduct ) Tj ET Q q 0 0 0 rg BT 347.25 63.80 Td (development ) Tj ET Q q 0 0 0 rg BT 400.28 63.80 Td (cycle.) Tj ET Q endstream endobj 41 0 obj <> endobj 42 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (20) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 749.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.08 749.25 Td (face ) Tj ET Q q 0 0 0 rg BT 70.78 749.25 Td (intense ) Tj ET Q q 0 0 0 rg BT 102.73 749.25 Td (competition ) Tj ET Q q 0 0 0 rg BT 153.55 749.25 Td (from ) Tj ET Q q 0 0 0 rg BT 176.04 749.25 Td (other ) Tj ET Q q 0 0 0 rg BT 200.21 749.25 Td (manufacturers, ) Tj ET Q q 0 0 0 rg BT 266.33 749.25 Td (including ) Tj ET Q q 0 0 0 rg BT 308.28 749.25 Td (for ) Tj ET Q q 0 0 0 rg BT 322.99 749.25 Td (both ) Tj ET Q q 0 0 0 rg BT 343.83 749.25 Td (innovative ) Tj ET Q q 0 0 0 rg BT 389.09 749.25 Td (medicines ) Tj ET Q q 0 0 0 rg BT 432.69 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 450.75 749.25 Td (lower-priced ) Tj ET Q q 0 0 0 rg BT 504.90 749.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 537.94 749.25 Td (products.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 57.48 737.25 Td (is ) Tj ET Q q 0 0 0 rg BT 66.19 737.25 Td (dependent ) Tj ET Q q 0 0 0 rg BT 109.33 737.25 Td (on ) Tj ET Q q 0 0 0 rg BT 121.37 737.25 Td (the ) Tj ET Q q 0 0 0 rg BT 135.63 737.25 Td (market ) Tj ET Q q 0 0 0 rg BT 165.44 737.25 Td (access, ) Tj ET Q q 0 0 0 rg BT 196.08 737.25 Td (uptake ) Tj ET Q q 0 0 0 rg BT 224.78 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 241.82 737.25 Td (expansion ) Tj ET Q q 0 0 0 rg BT 284.41 737.25 Td (for ) Tj ET Q q 0 0 0 rg BT 298.13 737.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 337.38 737.25 Td (brands, ) Tj ET Q q 0 0 0 rg BT 369.70 737.25 Td (new ) Tj ET Q q 0 0 0 rg BT 387.85 737.25 Td (pr) Tj ET Q q 0 0 0 rg BT 396.37 737.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 420.63 737.25 Td (intr) Tj ET Q q 0 0 0 rg BT 434.71 737.25 Td (oductions, ) Tj ET Q q 0 0 0 rg BT 478.14 737.25 Td (new ) Tj ET Q q 0 0 0 rg BT 496.29 737.25 Td (indications, ) Tj ET Q q 0 0 0 rg BT 545.27 737.25 Td (pr) Tj ET Q q 0 0 0 rg BT 553.79 737.25 Td (oduct ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (extensions ) Tj ET Q q 0 0 0 rg BT 80.71 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 98.77 725.25 Td (co-pr) Tj ET Q q 0 0 0 rg BT 120.06 725.25 Td (omotional ) Tj ET Q q 0 0 0 rg BT 163.67 725.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 202.82 725.25 Td (with ) Tj ET Q q 0 0 0 rg BT 223.10 725.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 258.37 725.25 Td (partners, ) Tj ET Q q 0 0 0 rg BT 297.82 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 308.65 725.25 Td (deliver ) Tj ET Q q 0 0 0 rg BT 339.47 725.25 Td (futur) Tj ET Q q 0 0 0 rg BT 358.55 725.25 Td (e ) Tj ET Q q 0 0 0 rg BT 366.04 725.25 Td (gr) Tj ET Q q 0 0 0 rg BT 374.56 725.25 Td (owth. ) Tj ET Q q 0 0 0 rg BT 399.57 725.25 Td (Competition ) Tj ET Q q 0 0 0 rg BT 452.07 725.25 Td (is ) Tj ET Q q 0 0 0 rg BT 461.79 725.25 Td (keen ) Tj ET Q q 0 0 0 rg BT 483.16 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 501.22 725.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 537.60 725.25 Td (\(i\) ) Tj ET Q q 0 0 0 rg BT 550.09 725.25 Td (lower) Tj ET Q q 0 0 0 rg BT 572.67 725.25 Td (-) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (priced ) Tj ET Q q 0 0 0 rg BT 65.59 713.25 Td (generics ) Tj ET Q q 0 0 0 rg BT 103.51 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 122.55 713.25 Td (incr) Tj ET Q q 0 0 0 rg BT 138.29 713.25 Td (easingly ) Tj ET Q q 0 0 0 rg BT 175.66 713.25 Td (aggr) Tj ET Q q 0 0 0 rg BT 194.18 713.25 Td (essive ) Tj ET Q q 0 0 0 rg BT 222.10 713.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 256.13 713.25 Td (commer) Tj ET Q q 0 0 0 rg BT 287.97 713.25 Td (cialization ) Tj ET Q q 0 0 0 rg BT 334.24 713.25 Td (tactics, ) Tj ET Q q 0 0 0 rg BT 366.88 713.25 Td (\(ii\) ) Tj ET Q q 0 0 0 rg BT 383.14 713.25 Td (new ) Tj ET Q q 0 0 0 rg BT 403.29 713.25 Td (competitive ) Tj ET Q q 0 0 0 rg BT 453.43 713.25 Td (pr) Tj ET Q q 0 0 0 rg BT 461.95 713.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 492.10 713.25 Td (entering ) Tj ET Q q 0 0 0 rg BT 529.47 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 545.73 713.25 Td (market, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (particularly ) Tj ET Q q 0 0 0 rg BT 86.32 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 96.64 701.25 Td (IO, ) Tj ET Q q 0 0 0 rg BT 112.24 701.25 Td (\(iii\) ) Tj ET Q q 0 0 0 rg BT 129.77 701.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 155.10 701.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 182.08 701.25 Td (for ) Tj ET Q q 0 0 0 rg BT 196.29 701.25 Td (other ) Tj ET Q q 0 0 0 rg BT 219.95 701.25 Td (companies' ) Tj ET Q q 0 0 0 rg BT 267.40 701.25 Td (pr) Tj ET Q q 0 0 0 rg BT 275.92 701.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 307.07 701.25 Td (r) Tj ET Q q 0 0 0 rg BT 310.59 701.25 Td (eal ) Tj ET Q q 0 0 0 rg BT 325.35 701.25 Td (or ) Tj ET Q q 0 0 0 rg BT 336.79 701.25 Td (per) Tj ET Q q 0 0 0 rg BT 349.75 701.25 Td (ceived ) Tj ET Q q 0 0 0 rg BT 377.82 701.25 Td (superior ) Tj ET Q q 0 0 0 rg BT 414.26 701.25 Td (efficacy ) Tj ET Q q 0 0 0 rg BT 447.89 701.25 Td (\(benefit\) ) Tj ET Q q 0 0 0 rg BT 484.31 701.25 Td (or ) Tj ET Q q 0 0 0 rg BT 495.74 701.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 521.61 701.25 Td (\(risk\) ) Tj ET Q q 0 0 0 rg BT 545.81 701.25 Td (pr) Tj ET Q q 0 0 0 rg BT 554.33 701.25 Td (ofiles ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (or ) Tj ET Q q 0 0 0 rg BT 47.49 689.25 Td (other ) Tj ET Q q 0 0 0 rg BT 71.21 689.25 Td (differ) Tj ET Q q 0 0 0 rg BT 92.50 689.25 Td (entiating ) Tj ET Q q 0 0 0 rg BT 130.65 689.25 Td (factors, ) Tj ET Q q 0 0 0 rg BT 163.53 689.25 Td (\(iv\) technological ) Tj ET Q q 0 0 0 rg BT 236.94 689.25 Td (advances ) Tj ET Q q 0 0 0 rg BT 276.75 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 294.35 689.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 325.84 689.25 Td (attained ) Tj ET Q q 0 0 0 rg BT 361.22 689.25 Td (by ) Tj ET Q q 0 0 0 rg BT 373.26 689.25 Td (our ) Tj ET Q q 0 0 0 rg BT 389.75 689.25 Td (competitors, ) Tj ET Q q 0 0 0 rg BT 442.07 689.25 Td (\(v\) ) Tj ET Q q 0 0 0 rg BT 455.78 689.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 488.37 689.25 Td (study ) Tj ET Q q 0 0 0 rg BT 512.08 689.25 Td (r) Tj ET Q q 0 0 0 rg BT 515.60 689.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 540.98 689.25 Td (fr) Tj ET Q q 0 0 0 rg BT 547.28 689.25 Td (om ) Tj ET Q q 0 0 0 rg BT 562.10 689.25 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 677.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 72.67 677.25 Td (or ) Tj ET Q q 0 0 0 rg BT 83.60 677.25 Td (a ) Tj ET Q q 0 0 0 rg BT 90.64 677.25 Td (competitor) Tj ET Q q 0 0 0 rg BT 134.33 677.25 Td (’) Tj ET Q q 0 0 0 rg BT 136.37 677.25 Td (s ) Tj ET Q q 0 0 0 rg BT 142.30 677.25 Td (pr) Tj ET Q q 0 0 0 rg BT 150.82 677.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 178.97 677.25 Td (that ) Tj ET Q q 0 0 0 rg BT 196.57 677.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 220.82 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 235.07 677.25 Td (value ) Tj ET Q q 0 0 0 rg BT 258.77 677.25 Td (pr) Tj ET Q q 0 0 0 rg BT 267.29 677.25 Td (oposition ) Tj ET Q q 0 0 0 rg BT 306.55 677.25 Td (for ) Tj ET Q q 0 0 0 rg BT 320.26 677.25 Td (our ) Tj ET Q q 0 0 0 rg BT 336.19 677.25 Td (pr) Tj ET Q q 0 0 0 rg BT 344.71 677.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 375.36 677.25 Td (\(vi\) business ) Tj ET Q q 0 0 0 rg BT 427.67 677.25 Td (combinations ) Tj ET Q q 0 0 0 rg BT 483.59 677.25 Td (among ) Tj ET Q q 0 0 0 rg BT 512.85 677.25 Td (our ) Tj ET Q q 0 0 0 rg BT 528.78 677.25 Td (competitors ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.17 665.25 Td (major ) Tj ET Q q 0 0 0 rg BT 79.23 665.25 Td (thir) Tj ET Q q 0 0 0 rg BT 93.30 665.25 Td (d-party ) Tj ET Q q 0 0 0 rg BT 124.91 665.25 Td (payers ) Tj ET Q q 0 0 0 rg BT 153.74 665.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.91 665.25 Td (\(vii\) competing ) Tj ET Q q 0 0 0 rg BT 233.89 665.25 Td (inter) Tj ET Q q 0 0 0 rg BT 252.40 665.25 Td (ests ) Tj ET Q q 0 0 0 rg BT 269.57 665.25 Td (for ) Tj ET Q q 0 0 0 rg BT 283.41 665.25 Td (external ) Tj ET Q q 0 0 0 rg BT 318.34 665.25 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 371.07 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 381.01 665.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 414.28 665.25 Td (and ) Tj ET Q q 0 0 0 rg BT 431.44 665.25 Td (bring ) Tj ET Q q 0 0 0 rg BT 455.28 665.25 Td (new ) Tj ET Q q 0 0 0 rg BT 473.56 665.25 Td (pr) Tj ET Q q 0 0 0 rg BT 482.08 665.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 510.36 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 520.30 665.25 Td (markets. ) Tj ET Q q 0 0 0 rg BT 556.63 665.25 Td (If ) Tj ET Q q 0 0 0 rg BT 564.91 665.25 Td (we ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (ar) Tj ET Q q 0 0 0 rg BT 44.52 653.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.39 653.25 Td (unable ) Tj ET Q q 0 0 0 rg BT 81.04 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 91.25 653.25 Td (compete ) Tj ET Q q 0 0 0 rg BT 127.00 653.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 177.19 653.25 Td (against ) Tj ET Q q 0 0 0 rg BT 209.07 653.25 Td (our ) Tj ET Q q 0 0 0 rg BT 225.39 653.25 Td (competitors' ) Tj ET Q q 0 0 0 rg BT 277.18 653.25 Td (pr) Tj ET Q q 0 0 0 rg BT 285.70 653.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 314.24 653.25 Td (in ) Tj ET Q q 0 0 0 rg BT 324.45 653.25 Td (the ) Tj ET Q q 0 0 0 rg BT 339.10 653.25 Td (marketplace, ) Tj ET Q q 0 0 0 rg BT 393.46 653.25 Td (this ) Tj ET Q q 0 0 0 rg BT 410.34 653.25 Td (could ) Tj ET Q q 0 0 0 rg BT 434.98 653.25 Td (have ) Tj ET Q q 0 0 0 rg BT 456.29 653.25 Td (a ) Tj ET Q q 0 0 0 rg BT 463.72 653.25 Td (material ) Tj ET Q q 0 0 0 rg BT 500.04 653.25 Td (negative ) Tj ET Q q 0 0 0 rg BT 536.35 653.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 566.00 653.25 Td (on ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (our ) Tj ET Q q 0 0 0 rg BT 52.39 641.25 Td (r) Tj ET Q q 0 0 0 rg BT 55.91 641.25 Td (evenues ) Tj ET Q q 0 0 0 rg BT 90.06 641.25 Td (and ) Tj ET Q q 0 0 0 rg BT 107.56 641.25 Td (earnings.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 79.06 617.25 Td (claiming ) Tj ET Q q 0 0 0 rg BT 117.67 617.25 Td (infringement ) Tj ET Q q 0 0 0 rg BT 174.07 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 184.90 617.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 233.51 617.25 Td (property ) Tj ET Q q 0 0 0 rg BT 270.45 617.25 Td (may ) Tj ET Q q 0 0 0 rg BT 290.17 617.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 330.98 617.25 Td (af) Tj ET Q q 0 0 0 rg BT 339.13 617.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 356.62 617.25 Td (our ) Tj ET Q q 0 0 0 rg BT 373.57 617.25 Td (future ) Tj ET Q q 0 0 0 rg BT 401.63 617.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 440.79 617.25 Td (and ) Tj ET Q q 0 0 0 rg BT 458.85 617.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 500.80 617.25 Td (earnings.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (Thir) Tj ET Q q 0 0 0 rg BT 52.86 605.25 Td (d ) Tj ET Q q 0 0 0 rg BT 60.50 605.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 90.93 605.25 Td (may ) Tj ET Q q 0 0 0 rg BT 110.23 605.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 135.09 605.25 Td (that ) Tj ET Q q 0 0 0 rg BT 153.29 605.25 Td (we ) Tj ET Q q 0 0 0 rg BT 167.04 605.25 Td (infringe ) Tj ET Q q 0 0 0 rg BT 201.35 605.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 224.00 605.25 Td (their ) Tj ET Q q 0 0 0 rg BT 245.53 605.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 293.16 605.25 Td (pr) Tj ET Q q 0 0 0 rg BT 301.68 605.25 Td (operty) Tj ET Q q 0 0 0 rg BT 326.67 605.25 Td (. ) Tj ET Q q 0 0 0 rg BT 331.82 605.25 Td (Resolving ) Tj ET Q q 0 0 0 rg BT 373.90 605.25 Td (an ) Tj ET Q q 0 0 0 rg BT 386.54 605.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 434.17 605.25 Td (pr) Tj ET Q q 0 0 0 rg BT 442.69 605.25 Td (operty ) Tj ET Q q 0 0 0 rg BT 470.88 605.25 Td (infringement ) Tj ET Q q 0 0 0 rg BT 524.63 605.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 549.49 605.25 Td (can ) Tj ET Q q 0 0 0 rg BT 566.57 605.25 Td (be ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (costly ) Tj ET Q q 0 0 0 rg BT 61.52 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 78.72 593.25 Td (time ) Tj ET Q q 0 0 0 rg BT 98.13 593.25 Td (consuming ) Tj ET Q q 0 0 0 rg BT 143.66 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 160.85 593.25 Td (may ) Tj ET Q q 0 0 0 rg BT 179.71 593.25 Td (r) Tj ET Q q 0 0 0 rg BT 183.23 593.25 Td (equir) Tj ET Q q 0 0 0 rg BT 203.97 593.25 Td (e ) Tj ET Q q 0 0 0 rg BT 210.60 593.25 Td (us ) Tj ET Q q 0 0 0 rg BT 221.69 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 231.67 593.25 Td (enter ) Tj ET Q q 0 0 0 rg BT 254.41 593.25 Td (into ) Tj ET Q q 0 0 0 rg BT 272.16 593.25 Td (license ) Tj ET Q q 0 0 0 rg BT 302.12 593.25 Td (agr) Tj ET Q q 0 0 0 rg BT 315.64 593.25 Td (eements, ) Tj ET Q q 0 0 0 rg BT 352.54 593.25 Td (which ) Tj ET Q q 0 0 0 rg BT 378.63 593.25 Td (may ) Tj ET Q q 0 0 0 rg BT 397.48 593.25 Td (not ) Tj ET Q q 0 0 0 rg BT 412.46 593.25 Td (be ) Tj ET Q q 0 0 0 rg BT 424.09 593.25 Td (available ) Tj ET Q q 0 0 0 rg BT 463.50 593.25 Td (on ) Tj ET Q q 0 0 0 rg BT 475.70 593.25 Td (commer) Tj ET Q q 0 0 0 rg BT 507.54 593.25 Td (cially ) Tj ET Q q 0 0 0 rg BT 531.95 593.25 Td (r) Tj ET Q q 0 0 0 rg BT 535.47 593.25 Td (easonable ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (terms. ) Tj ET Q q 0 0 0 rg BT 63.14 581.25 Td (A) Tj ET Q q 0 0 0 rg BT 69.06 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 71.66 581.25 Td (successful ) Tj ET Q q 0 0 0 rg BT 114.81 581.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 139.63 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 150.01 581.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 177.61 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 189.10 581.25 Td (other ) Tj ET Q q 0 0 0 rg BT 212.81 581.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 260.40 581.25 Td (pr) Tj ET Q q 0 0 0 rg BT 268.92 581.25 Td (operty ) Tj ET Q q 0 0 0 rg BT 297.07 581.25 Td (infringement ) Tj ET Q q 0 0 0 rg BT 350.77 581.25 Td (could ) Tj ET Q q 0 0 0 rg BT 375.59 581.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 406.52 581.25 Td (us ) Tj ET Q q 0 0 0 rg BT 418.01 581.25 Td (to ) Tj ET Q q 0 0 0 rg BT 428.39 581.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 473.21 581.25 Td (damages ) Tj ET Q q 0 0 0 rg BT 511.37 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 522.86 581.25 Td (an ) Tj ET Q q 0 0 0 rg BT 535.46 581.25 Td (injunction ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 569.25 Td (eventing ) Tj ET Q q 0 0 0 rg BT 80.76 569.25 Td (the ) Tj ET Q q 0 0 0 rg BT 95.34 569.25 Td (manufactur) Tj ET Q q 0 0 0 rg BT 141.08 569.25 Td (e, ) Tj ET Q q 0 0 0 rg BT 150.39 569.25 Td (sale, ) Tj ET Q q 0 0 0 rg BT 171.36 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 182.62 569.25 Td (use ) Tj ET Q q 0 0 0 rg BT 198.32 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 208.46 569.25 Td (the ) Tj ET Q q 0 0 0 rg BT 223.05 569.25 Td (affected ) Tj ET Q q 0 0 0 rg BT 257.07 569.25 Td (pr) Tj ET Q q 0 0 0 rg BT 265.59 569.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 290.17 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 301.43 569.25 Td (pr) Tj ET Q q 0 0 0 rg BT 309.95 569.25 Td (oducts. ) Tj ET Q q 0 0 0 rg BT 340.75 569.25 Td (Any ) Tj ET Q q 0 0 0 rg BT 358.67 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 368.81 569.25 Td (these ) Tj ET Q q 0 0 0 rg BT 391.73 569.25 Td (events ) Tj ET Q q 0 0 0 rg BT 419.08 569.25 Td (could ) Tj ET Q q 0 0 0 rg BT 443.66 569.25 Td (have ) Tj ET Q q 0 0 0 rg BT 464.91 569.25 Td (a ) Tj ET Q q 0 0 0 rg BT 472.27 569.25 Td (material ) Tj ET Q q 0 0 0 rg BT 508.53 569.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 541.99 569.25 Td (effect ) Tj ET Q q 0 0 0 rg BT 566.01 569.25 Td (on ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (our ) Tj ET Q q 0 0 0 rg BT 52.39 557.25 Td (pr) Tj ET Q q 0 0 0 rg BT 60.91 557.25 Td (ofitability ) Tj ET Q q 0 0 0 rg BT 102.30 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 119.80 557.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 157.85 557.25 Td (condition.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (Adverse ) Tj ET Q q 0 0 0 rg BT 71.27 533.25 Td (outcomes ) Tj ET Q q 0 0 0 rg BT 112.66 533.25 Td (in ) Tj ET Q q 0 0 0 rg BT 123.50 533.25 Td (other ) Tj ET Q q 0 0 0 rg BT 147.67 533.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 170.16 533.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 203.22 533.25 Td (could ) Tj ET Q q 0 0 0 rg BT 228.50 533.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 272.65 533.25 Td (af) Tj ET Q q 0 0 0 rg BT 280.79 533.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 298.28 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 315.23 533.25 Td (business.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (Curr) Tj ET Q q 0 0 0 rg BT 55.08 521.25 Td (ent ) Tj ET Q q 0 0 0 rg BT 70.48 521.25 Td (or ) Tj ET Q q 0 0 0 rg BT 82.54 521.25 Td (futur) Tj ET Q q 0 0 0 rg BT 101.62 521.25 Td (e ) Tj ET Q q 0 0 0 rg BT 109.23 521.25 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 147.70 521.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 179.48 521.25 Td (pr) Tj ET Q q 0 0 0 rg BT 188.00 521.25 Td (oceedings ) Tj ET Q q 0 0 0 rg BT 231.17 521.25 Td (and ) Tj ET Q q 0 0 0 rg BT 249.34 521.25 Td (government ) Tj ET Q q 0 0 0 rg BT 299.73 521.25 Td (investigations ) Tj ET Q q 0 0 0 rg BT 358.45 521.25 Td (could ) Tj ET Q q 0 0 0 rg BT 383.85 521.25 Td (pr) Tj ET Q q 0 0 0 rg BT 392.37 521.25 Td (eclude ) Tj ET Q q 0 0 0 rg BT 421.64 521.25 Td (or ) Tj ET Q q 0 0 0 rg BT 433.71 521.25 Td (delay ) Tj ET Q q 0 0 0 rg BT 458.54 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 473.93 521.25 Td (commer) Tj ET Q q 0 0 0 rg BT 505.77 521.25 Td (cialization ) Tj ET Q q 0 0 0 rg BT 551.17 521.25 Td (of ) Tj ET Q q 0 0 0 rg BT 562.12 521.25 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 509.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 72.99 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 84.25 509.25 Td (could ) Tj ET Q q 0 0 0 rg BT 108.83 509.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 149.52 509.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 174.09 509.25 Td (our ) Tj ET Q q 0 0 0 rg BT 190.35 509.25 Td (operations, ) Tj ET Q q 0 0 0 rg BT 237.99 509.25 Td (pr) Tj ET Q q 0 0 0 rg BT 246.52 509.25 Td (ofitability) Tj ET Q q 0 0 0 rg BT 284.85 509.25 Td (, ) Tj ET Q q 0 0 0 rg BT 289.72 509.25 Td (liquidity ) Tj ET Q q 0 0 0 rg BT 325.41 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 336.67 509.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 374.59 509.25 Td (condition, ) Tj ET Q q 0 0 0 rg BT 417.23 509.25 Td (after ) Tj ET Q q 0 0 0 rg BT 438.48 509.25 Td (any ) Tj ET Q q 0 0 0 rg BT 455.28 509.25 Td (possible ) Tj ET Q q 0 0 0 rg BT 490.43 509.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 532.23 509.25 Td (r) Tj ET Q q 0 0 0 rg BT 535.75 509.25 Td (ecoveries, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (wher) Tj ET Q q 0 0 0 rg BT 55.63 497.25 Td (e ) Tj ET Q q 0 0 0 rg BT 61.52 497.25 Td (available. ) Tj ET Q q 0 0 0 rg BT 102.67 497.25 Td (Such ) Tj ET Q q 0 0 0 rg BT 123.56 497.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 145.00 497.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 176.45 497.25 Td (include ) Tj ET Q q 0 0 0 rg BT 207.33 497.25 Td (\(i\) intellectual ) Tj ET Q q 0 0 0 rg BT 265.70 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 274.23 497.25 Td (operty ) Tj ET Q q 0 0 0 rg BT 301.22 497.25 Td (disputes; ) Tj ET Q q 0 0 0 rg BT 338.78 497.25 Td (\(ii\) ) Tj ET Q q 0 0 0 rg BT 352.44 497.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 384.99 497.25 Td (decisions ) Tj ET Q q 0 0 0 rg BT 423.65 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 432.88 497.25 Td (litigation, ) Tj ET Q q 0 0 0 rg BT 473.50 497.25 Td (including ) Tj ET Q q 0 0 0 rg BT 512.72 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 521.24 497.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 544.90 497.25 Td (liability ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 54.84 485.25 Td (commer) Tj ET Q q 0 0 0 rg BT 86.69 485.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 105.53 485.25 Td (cases; ) Tj ET Q q 0 0 0 rg BT 134.36 485.25 Td (\(iii\) anti-bribery ) Tj ET Q q 0 0 0 rg BT 204.03 485.25 Td (r) Tj ET Q q 0 0 0 rg BT 207.55 485.25 Td (egulations, ) Tj ET Q q 0 0 0 rg BT 255.56 485.25 Td (such ) Tj ET Q q 0 0 0 rg BT 277.73 485.25 Td (as ) Tj ET Q q 0 0 0 rg BT 290.47 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 306.53 485.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 327.59 485.25 Td (For) Tj ET Q q 0 0 0 rg BT 342.22 485.25 Td (eign ) Tj ET Q q 0 0 0 rg BT 363.29 485.25 Td (Corrupt ) Tj ET Q q 0 0 0 rg BT 399.36 485.25 Td (Practice ) Tj ET Q q 0 0 0 rg BT 436.80 485.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 453.97 485.25 Td (or ) Tj ET Q q 0 0 0 rg BT 466.71 485.25 Td (UK ) Tj ET Q q 0 0 0 rg BT 484.44 485.25 Td (Bribery ) Tj ET Q q 0 0 0 rg BT 518.56 485.25 Td (Act, ) Tj ET Q q 0 0 0 rg BT 538.23 485.25 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (compliance ) Tj ET Q q 0 0 0 rg BT 86.62 473.25 Td (with ) Tj ET Q q 0 0 0 rg BT 108.37 473.25 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 145.67 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 149.19 473.25 Td (eporting ) Tj ET Q q 0 0 0 rg BT 187.60 473.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 237.12 473.25 Td (to ) Tj ET Q q 0 0 0 rg BT 249.42 473.25 Td (the ) Tj ET Q q 0 0 0 rg BT 266.16 473.25 Td (government ) Tj ET Q q 0 0 0 rg BT 317.89 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 321.41 473.25 Td (esulting ) Tj ET Q q 0 0 0 rg BT 357.60 473.25 Td (fr) Tj ET Q q 0 0 0 rg BT 363.90 473.25 Td (om ) Tj ET Q q 0 0 0 rg BT 380.64 473.25 Td (any ) Tj ET Q q 0 0 0 rg BT 399.60 473.25 Td (settlements, ) Tj ET Q q 0 0 0 rg BT 451.06 473.25 Td (\(iv\) ) Tj ET Q q 0 0 0 rg BT 469.46 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 472.98 473.25 Td (ecalls ) Tj ET Q q 0 0 0 rg BT 500.83 473.25 Td (or ) Tj ET Q q 0 0 0 rg BT 514.24 473.25 Td (withdrawals ) Tj ET Q q 0 0 0 rg BT 568.22 473.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 101.04 461.25 Td (pr) Tj ET Q q 0 0 0 rg BT 109.56 461.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 137.94 461.25 Td (or ) Tj ET Q q 0 0 0 rg BT 149.11 461.25 Td (for) Tj ET Q q 0 0 0 rg BT 160.41 461.25 Td (ced ) Tj ET Q q 0 0 0 rg BT 176.56 461.25 Td (closings ) Tj ET Q q 0 0 0 rg BT 211.61 461.25 Td (of ) Tj ET Q q 0 0 0 rg BT 221.66 461.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 282.82 461.25 Td (plants; ) Tj ET Q q 0 0 0 rg BT 312.88 461.25 Td (\(v\) the ) Tj ET Q q 0 0 0 rg BT 340.97 461.25 Td (failur) Tj ET Q q 0 0 0 rg BT 362.82 461.25 Td (e ) Tj ET Q q 0 0 0 rg BT 369.54 461.25 Td (to ) Tj ET Q q 0 0 0 rg BT 379.59 461.25 Td (fulfill ) Tj ET Q q 0 0 0 rg BT 403.53 461.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 450.81 461.25 Td (under ) Tj ET Q q 0 0 0 rg BT 476.42 461.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 504.80 461.25 Td (contracts ) Tj ET Q q 0 0 0 rg BT 544.29 461.25 Td (with ) Tj ET Q q 0 0 0 rg BT 563.79 461.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (government ) Tj ET Q q 0 0 0 rg BT 86.26 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 104.31 449.25 Td (other ) Tj ET Q q 0 0 0 rg BT 128.48 449.25 Td (customers; ) Tj ET Q q 0 0 0 rg BT 175.41 449.25 Td (\(vi\) pr) Tj ET Q q 0 0 0 rg BT 200.31 449.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 225.58 449.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 257.52 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 275.57 449.25 Td (pr) Tj ET Q q 0 0 0 rg BT 284.09 449.25 Td (omotional ) Tj ET Q q 0 0 0 rg BT 327.70 449.25 Td (matters; ) Tj ET Q q 0 0 0 rg BT 364.08 449.25 Td (\(vii\) lawsuits ) Tj ET Q q 0 0 0 rg BT 419.08 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 437.13 449.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 466.30 449.25 Td (asserting, ) Tj ET Q q 0 0 0 rg BT 508.52 449.25 Td (or ) Tj ET Q q 0 0 0 rg BT 520.46 449.25 Td (investigations ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (into, ) Tj ET Q q 0 0 0 rg BT 56.00 437.25 Td (violations ) Tj ET Q q 0 0 0 rg BT 97.39 437.25 Td (of ) Tj ET Q q 0 0 0 rg BT 107.11 437.25 Td (securities, ) Tj ET Q q 0 0 0 rg BT 149.88 437.25 Td (antitrust, ) Tj ET Q q 0 0 0 rg BT 188.22 437.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 221.82 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 238.76 437.25 Td (state ) Tj ET Q q 0 0 0 rg BT 259.59 437.25 Td (pricing, ) Tj ET Q q 0 0 0 rg BT 292.92 437.25 Td (consumer ) Tj ET Q q 0 0 0 rg BT 333.74 437.25 Td (pr) Tj ET Q q 0 0 0 rg BT 342.26 437.25 Td (otection, ) Tj ET Q q 0 0 0 rg BT 378.92 437.25 Td (data ) Tj ET Q q 0 0 0 rg BT 398.64 437.25 Td (privacy ) Tj ET Q q 0 0 0 rg BT 430.57 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 447.51 437.25 Td (other ) Tj ET Q q 0 0 0 rg BT 470.57 437.25 Td (laws; ) Tj ET Q q 0 0 0 rg BT 494.18 437.25 Td (\(viii\) envir) Tj ET Q q 0 0 0 rg BT 536.29 437.25 Td (onmental, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (health, ) Tj ET Q q 0 0 0 rg BT 66.00 425.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 91.82 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 109.32 425.25 Td (sustainability ) Tj ET Q q 0 0 0 rg BT 165.71 425.25 Td (matters; ) Tj ET Q q 0 0 0 rg BT 201.54 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 219.04 425.25 Td (\(ix\) tax ) Tj ET Q q 0 0 0 rg BT 250.14 425.25 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 290.41 425.25 Td (r) Tj ET Q q 0 0 0 rg BT 293.93 425.25 Td (esulting ) Tj ET Q q 0 0 0 rg BT 328.10 425.25 Td (fr) Tj ET Q q 0 0 0 rg BT 334.40 425.25 Td (om ) Tj ET Q q 0 0 0 rg BT 349.12 425.25 Td (assessments ) Tj ET Q q 0 0 0 rg BT 399.96 425.25 Td (fr) Tj ET Q q 0 0 0 rg BT 406.25 425.25 Td (om ) Tj ET Q q 0 0 0 rg BT 420.98 425.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 435.69 425.25 Td (authorities.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 401.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.09 401.25 Td (could ) Tj ET Q q 0 0 0 rg BT 76.37 401.25 Td (lose ) Tj ET Q q 0 0 0 rg BT 94.97 401.25 Td (market ) Tj ET Q q 0 0 0 rg BT 126.36 401.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 172.18 401.25 Td (of ) Tj ET Q q 0 0 0 rg BT 183.01 401.25 Td (a ) Tj ET Q q 0 0 0 rg BT 190.51 401.25 Td (product ) Tj ET Q q 0 0 0 rg BT 224.68 401.25 Td (earlier ) Tj ET Q q 0 0 0 rg BT 254.40 401.25 Td (than ) Tj ET Q q 0 0 0 rg BT 275.80 401.25 Td (expected.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.00 389.25 Td (the ) Tj ET Q q 0 0 0 rg BT 59.88 389.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 124.31 389.25 Td (and ) Tj ET Q q 0 0 0 rg BT 140.98 389.25 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 199.29 389.25 Td (industries, ) Tj ET Q q 0 0 0 rg BT 242.91 389.25 Td (the ) Tj ET Q q 0 0 0 rg BT 256.79 389.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 292.34 389.25 Td (of ) Tj ET Q q 0 0 0 rg BT 301.79 389.25 Td (an ) Tj ET Q q 0 0 0 rg BT 313.46 389.25 Td (innovative ) Tj ET Q q 0 0 0 rg BT 356.77 389.25 Td (pr) Tj ET Q q 0 0 0 rg BT 365.29 389.25 Td (oduct’) Tj ET Q q 0 0 0 rg BT 389.55 389.25 Td (s ) Tj ET Q q 0 0 0 rg BT 395.11 389.25 Td (commer) Tj ET Q q 0 0 0 rg BT 426.95 389.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 443.61 389.25 Td (value ) Tj ET Q q 0 0 0 rg BT 466.93 389.25 Td (is ) Tj ET Q q 0 0 0 rg BT 475.27 389.25 Td (r) Tj ET Q q 0 0 0 rg BT 478.79 389.25 Td (ealized ) Tj ET Q q 0 0 0 rg BT 508.78 389.25 Td (during ) Tj ET Q q 0 0 0 rg BT 537.12 389.25 Td (its ) Tj ET Q q 0 0 0 rg BT 548.23 389.25 Td (market ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 377.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 81.57 377.25 Td (period. ) Tj ET Q q 0 0 0 rg BT 113.54 377.25 Td (In ) Tj ET Q q 0 0 0 rg BT 125.24 377.25 Td (the ) Tj ET Q q 0 0 0 rg BT 140.83 377.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 161.42 377.25 Td (and ) Tj ET Q q 0 0 0 rg BT 179.79 377.25 Td (in ) Tj ET Q q 0 0 0 rg BT 190.94 377.25 Td (some ) Tj ET Q q 0 0 0 rg BT 214.86 377.25 Td (other ) Tj ET Q q 0 0 0 rg BT 239.33 377.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 282.42 377.25 Td (when ) Tj ET Q q 0 0 0 rg BT 306.90 377.25 Td (market ) Tj ET Q q 0 0 0 rg BT 338.04 377.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 383.60 377.25 Td (expir) Tj ET Q q 0 0 0 rg BT 403.78 377.25 Td (es ) Tj ET Q q 0 0 0 rg BT 415.48 377.25 Td (and ) Tj ET Q q 0 0 0 rg BT 433.85 377.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 467.20 377.25 Td (versions ) Tj ET Q q 0 0 0 rg BT 503.90 377.25 Td (ar) Tj ET Q q 0 0 0 rg BT 512.42 377.25 Td (e ) Tj ET Q q 0 0 0 rg BT 520.23 377.25 Td (appr) Tj ET Q q 0 0 0 rg BT 538.75 377.25 Td (oved ) Tj ET Q q 0 0 0 rg BT 561.00 377.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 365.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 75.21 365.25 Td (or ) Tj ET Q q 0 0 0 rg BT 86.10 365.25 Td (when ) Tj ET Q q 0 0 0 rg BT 109.21 365.25 Td (biosimilars ) Tj ET Q q 0 0 0 rg BT 156.22 365.25 Td (ar) Tj ET Q q 0 0 0 rg BT 164.74 365.25 Td (e ) Tj ET Q q 0 0 0 rg BT 171.18 365.25 Td (intr) Tj ET Q q 0 0 0 rg BT 185.26 365.25 Td (oduced ) Tj ET Q q 0 0 0 rg BT 216.14 365.25 Td (\(even ) Tj ET Q q 0 0 0 rg BT 239.78 365.25 Td (if ) Tj ET Q q 0 0 0 rg BT 247.34 365.25 Td (only ) Tj ET Q q 0 0 0 rg BT 266.56 365.25 Td (for ) Tj ET Q q 0 0 0 rg BT 280.23 365.25 Td (a ) Tj ET Q q 0 0 0 rg BT 287.23 365.25 Td (competing ) Tj ET Q q 0 0 0 rg BT 330.89 365.25 Td (pr) Tj ET Q q 0 0 0 rg BT 339.41 365.25 Td (oduct\), ) Tj ET Q q 0 0 0 rg BT 369.45 365.25 Td (ther) Tj ET Q q 0 0 0 rg BT 385.19 365.25 Td (e ) Tj ET Q q 0 0 0 rg BT 391.63 365.25 Td (ar) Tj ET Q q 0 0 0 rg BT 400.15 365.25 Td (e ) Tj ET Q q 0 0 0 rg BT 406.59 365.25 Td (usually ) Tj ET Q q 0 0 0 rg BT 437.48 365.25 Td (very ) Tj ET Q q 0 0 0 rg BT 456.69 365.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 502.58 365.25 Td (and ) Tj ET Q q 0 0 0 rg BT 519.58 365.25 Td (rapid ) Tj ET Q q 0 0 0 rg BT 543.26 365.25 Td (declines ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 353.25 Td (a ) Tj ET Q q 0 0 0 rg BT 53.78 353.25 Td (pr) Tj ET Q q 0 0 0 rg BT 62.30 353.25 Td (oduct’) Tj ET Q q 0 0 0 rg BT 86.56 353.25 Td (s ) Tj ET Q q 0 0 0 rg BT 92.95 353.25 Td (r) Tj ET Q q 0 0 0 rg BT 96.47 353.25 Td (evenues.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 329.25 Td (Market ) Tj ET Q q 0 0 0 rg BT 66.91 329.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 111.15 329.25 Td (for ) Tj ET Q q 0 0 0 rg BT 124.85 329.25 Td (our ) Tj ET Q q 0 0 0 rg BT 140.78 329.25 Td (pr) Tj ET Q q 0 0 0 rg BT 149.30 329.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 177.45 329.25 Td (is ) Tj ET Q q 0 0 0 rg BT 186.15 329.25 Td (based ) Tj ET Q q 0 0 0 rg BT 211.52 329.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 233.55 329.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 260.58 329.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 285.96 329.25 Td (and ) Tj ET Q q 0 0 0 rg BT 303.00 329.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 333.36 329.25 Td (r) Tj ET Q q 0 0 0 rg BT 336.88 329.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 377.24 329.25 Td (forms ) Tj ET Q q 0 0 0 rg BT 402.06 329.25 Td (of ) Tj ET Q q 0 0 0 rg BT 411.87 329.25 Td (exclusivity) Tj ET Q q 0 0 0 rg BT 453.52 329.25 Td (. ) Tj ET Q q 0 0 0 rg BT 458.06 329.25 Td (The ) Tj ET Q q 0 0 0 rg BT 475.09 329.25 Td (scope ) Tj ET Q q 0 0 0 rg BT 499.90 329.25 Td (of ) Tj ET Q q 0 0 0 rg BT 509.71 329.25 Td (our ) Tj ET Q q 0 0 0 rg BT 525.64 329.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 552.67 329.25 Td (rights ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 317.25 Td (varies ) Tj ET Q q 0 0 0 rg BT 63.11 317.25 Td (fr) Tj ET Q q 0 0 0 rg BT 69.41 317.25 Td (om ) Tj ET Q q 0 0 0 rg BT 84.30 317.25 Td (country ) Tj ET Q q 0 0 0 rg BT 117.51 317.25 Td (to ) Tj ET Q q 0 0 0 rg BT 127.96 317.25 Td (country ) Tj ET Q q 0 0 0 rg BT 161.17 317.25 Td (and ) Tj ET Q q 0 0 0 rg BT 178.84 317.25 Td (may ) Tj ET Q q 0 0 0 rg BT 198.17 317.25 Td (also ) Tj ET Q q 0 0 0 rg BT 217.51 317.25 Td (be ) Tj ET Q q 0 0 0 rg BT 229.62 317.25 Td (dependent ) Tj ET Q q 0 0 0 rg BT 273.38 317.25 Td (on ) Tj ET Q q 0 0 0 rg BT 286.05 317.25 Td (the ) Tj ET Q q 0 0 0 rg BT 300.93 317.25 Td (availability ) Tj ET Q q 0 0 0 rg BT 349.15 317.25 Td (of ) Tj ET Q q 0 0 0 rg BT 359.59 317.25 Td (meaningful ) Tj ET Q q 0 0 0 rg BT 407.26 317.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 429.92 317.25 Td (r) Tj ET Q q 0 0 0 rg BT 433.44 317.25 Td (emedies ) Tj ET Q q 0 0 0 rg BT 468.32 317.25 Td (in ) Tj ET Q q 0 0 0 rg BT 478.76 317.25 Td (a ) Tj ET Q q 0 0 0 rg BT 486.43 317.25 Td (country) Tj ET Q q 0 0 0 rg BT 516.43 317.25 Td (. ) Tj ET Q q 0 0 0 rg BT 521.60 317.25 Td (The ) Tj ET Q q 0 0 0 rg BT 539.26 317.25 Td (failur) Tj ET Q q 0 0 0 rg BT 561.12 317.25 Td (e ) Tj ET Q q 0 0 0 rg BT 568.23 317.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 305.25 Td (obtain ) Tj ET Q q 0 0 0 rg BT 64.65 305.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 92.75 305.25 Td (and ) Tj ET Q q 0 0 0 rg BT 110.84 305.25 Td (other ) Tj ET Q q 0 0 0 rg BT 135.05 305.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 183.13 305.25 Td (pr) Tj ET Q q 0 0 0 rg BT 191.65 305.25 Td (operty ) Tj ET Q q 0 0 0 rg BT 220.30 305.25 Td (rights, ) Tj ET Q q 0 0 0 rg BT 249.23 305.25 Td (or ) Tj ET Q q 0 0 0 rg BT 261.22 305.25 Td (limitations ) Tj ET Q q 0 0 0 rg BT 307.10 305.25 Td (on ) Tj ET Q q 0 0 0 rg BT 320.20 305.25 Td (the ) Tj ET Q q 0 0 0 rg BT 335.51 305.25 Td (use ) Tj ET Q q 0 0 0 rg BT 351.94 305.25 Td (or ) Tj ET Q q 0 0 0 rg BT 363.93 305.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 382.59 305.25 Td (of ) Tj ET Q q 0 0 0 rg BT 393.46 305.25 Td (such ) Tj ET Q q 0 0 0 rg BT 414.89 305.25 Td (rights, ) Tj ET Q q 0 0 0 rg BT 443.83 305.25 Td (could ) Tj ET Q q 0 0 0 rg BT 469.14 305.25 Td (be ) Tj ET Q q 0 0 0 rg BT 481.68 305.25 Td (material ) Tj ET Q q 0 0 0 rg BT 518.66 305.25 Td (to ) Tj ET Q q 0 0 0 rg BT 529.54 305.25 Td (us. ) Tj ET Q q 0 0 0 rg BT 544.03 305.25 Td (In ) Tj ET Q q 0 0 0 rg BT 555.45 305.25 Td (some ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 293.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 77.89 293.25 Td (including ) Tj ET Q q 0 0 0 rg BT 117.85 293.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 148.35 293.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 163.86 293.25 Td (member ) Tj ET Q q 0 0 0 rg BT 198.25 293.25 Td (states, ) Tj ET Q q 0 0 0 rg BT 225.70 293.25 Td (basic ) Tj ET Q q 0 0 0 rg BT 248.99 293.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 276.16 293.25 Td (pr) Tj ET Q q 0 0 0 rg BT 284.68 293.25 Td (otections ) Tj ET Q q 0 0 0 rg BT 322.96 293.25 Td (for ) Tj ET Q q 0 0 0 rg BT 336.81 293.25 Td (our ) Tj ET Q q 0 0 0 rg BT 352.88 293.25 Td (pr) Tj ET Q q 0 0 0 rg BT 361.40 293.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 389.69 293.25 Td (may ) Tj ET Q q 0 0 0 rg BT 408.52 293.25 Td (not ) Tj ET Q q 0 0 0 rg BT 423.48 293.25 Td (exist ) Tj ET Q q 0 0 0 rg BT 443.98 293.25 Td (because ) Tj ET Q q 0 0 0 rg BT 478.37 293.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 508.87 293.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 548.27 293.25 Td (did ) Tj ET Q q 0 0 0 rg BT 563.22 293.25 Td (not ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 281.25 Td (historically ) Tj ET Q q 0 0 0 rg BT 83.99 281.25 Td (offer ) Tj ET Q q 0 0 0 rg BT 105.32 281.25 Td (the ) Tj ET Q q 0 0 0 rg BT 119.98 281.25 Td (right ) Tj ET Q q 0 0 0 rg BT 141.88 281.25 Td (to ) Tj ET Q q 0 0 0 rg BT 152.10 281.25 Td (obtain ) Tj ET Q q 0 0 0 rg BT 180.10 281.25 Td (specific ) Tj ET Q q 0 0 0 rg BT 213.08 281.25 Td (types ) Tj ET Q q 0 0 0 rg BT 236.07 281.25 Td (of ) Tj ET Q q 0 0 0 rg BT 246.29 281.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 277.62 281.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 306.73 281.25 Td (we ) Tj ET Q q 0 0 0 rg BT 320.29 281.25 Td (\(or ) Tj ET Q q 0 0 0 rg BT 334.95 281.25 Td (our ) Tj ET Q q 0 0 0 rg BT 351.28 281.25 Td (licensors\) ) Tj ET Q q 0 0 0 rg BT 393.17 281.25 Td (did ) Tj ET Q q 0 0 0 rg BT 408.39 281.25 Td (not ) Tj ET Q q 0 0 0 rg BT 423.61 281.25 Td (file ) Tj ET Q q 0 0 0 rg BT 438.82 281.25 Td (in ) Tj ET Q q 0 0 0 rg BT 449.05 281.25 Td (those ) Tj ET Q q 0 0 0 rg BT 472.60 281.25 Td (countries. ) Tj ET Q q 0 0 0 rg BT 514.76 281.25 Td (In ) Tj ET Q q 0 0 0 rg BT 525.53 281.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 563.81 281.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 269.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 62.89 269.25 Td (envir) Tj ET Q q 0 0 0 rg BT 83.06 269.25 Td (onment ) Tj ET Q q 0 0 0 rg BT 114.40 269.25 Td (can ) Tj ET Q q 0 0 0 rg BT 130.73 269.25 Td (be ) Tj ET Q q 0 0 0 rg BT 142.06 269.25 Td (unpr) Tj ET Q q 0 0 0 rg BT 160.58 269.25 Td (edictable ) Tj ET Q q 0 0 0 rg BT 199.13 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 216.02 269.25 Td (the ) Tj ET Q q 0 0 0 rg BT 230.13 269.25 Td (validity ) Tj ET Q q 0 0 0 rg BT 262.01 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 278.91 269.25 Td (enfor) Tj ET Q q 0 0 0 rg BT 299.64 269.25 Td (ceability ) Tj ET Q q 0 0 0 rg BT 335.97 269.25 Td (of ) Tj ET Q q 0 0 0 rg BT 345.64 269.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 376.42 269.25 Td (cannot ) Tj ET Q q 0 0 0 rg BT 405.53 269.25 Td (be ) Tj ET Q q 0 0 0 rg BT 416.86 269.25 Td (pr) Tj ET Q q 0 0 0 rg BT 425.38 269.25 Td (edicted ) Tj ET Q q 0 0 0 rg BT 456.15 269.25 Td (with ) Tj ET Q q 0 0 0 rg BT 475.27 269.25 Td (certainty) Tj ET Q q 0 0 0 rg BT 510.26 269.25 Td (. ) Tj ET Q q 0 0 0 rg BT 514.51 269.25 Td (Absent ) Tj ET Q q 0 0 0 rg BT 543.62 269.25 Td (r) Tj ET Q q 0 0 0 rg BT 547.14 269.25 Td (elevant ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 257.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 63.50 257.25 Td (pr) Tj ET Q q 0 0 0 rg BT 72.02 257.25 Td (otection ) Tj ET Q q 0 0 0 rg BT 106.73 257.25 Td (for ) Tj ET Q q 0 0 0 rg BT 120.90 257.25 Td (a ) Tj ET Q q 0 0 0 rg BT 128.40 257.25 Td (pr) Tj ET Q q 0 0 0 rg BT 136.92 257.25 Td (oduct, ) Tj ET Q q 0 0 0 rg BT 164.13 257.25 Td (once ) Tj ET Q q 0 0 0 rg BT 185.51 257.25 Td (the ) Tj ET Q q 0 0 0 rg BT 200.23 257.25 Td (data ) Tj ET Q q 0 0 0 rg BT 220.51 257.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 265.20 257.25 Td (period ) Tj ET Q q 0 0 0 rg BT 293.81 257.25 Td (expir) Tj ET Q q 0 0 0 rg BT 313.99 257.25 Td (es, ) Tj ET Q q 0 0 0 rg BT 327.32 257.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 359.80 257.25 Td (versions ) Tj ET Q q 0 0 0 rg BT 395.63 257.25 Td (can ) Tj ET Q q 0 0 0 rg BT 412.57 257.25 Td (be ) Tj ET Q q 0 0 0 rg BT 424.51 257.25 Td (appr) Tj ET Q q 0 0 0 rg BT 443.03 257.25 Td (oved ) Tj ET Q q 0 0 0 rg BT 464.41 257.25 Td (and ) Tj ET Q q 0 0 0 rg BT 481.91 257.25 Td (marketed. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 233.25 Td (Generic ) Tj ET Q q 0 0 0 rg BT 70.51 233.25 Td (and ) Tj ET Q q 0 0 0 rg BT 87.80 233.25 Td (biosimilar ) Tj ET Q q 0 0 0 rg BT 131.22 233.25 Td (pr) Tj ET Q q 0 0 0 rg BT 139.74 233.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 164.26 233.25 Td (manufactur) Tj ET Q q 0 0 0 rg BT 210.00 233.25 Td (ers ) Tj ET Q q 0 0 0 rg BT 224.52 233.25 Td (as ) Tj ET Q q 0 0 0 rg BT 235.71 233.25 Td (well ) Tj ET Q q 0 0 0 rg BT 254.67 233.25 Td (as ) Tj ET Q q 0 0 0 rg BT 265.86 233.25 Td (other ) Tj ET Q q 0 0 0 rg BT 289.27 233.25 Td (gr) Tj ET Q q 0 0 0 rg BT 297.79 233.25 Td (oups ) Tj ET Q q 0 0 0 rg BT 318.98 233.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 351.26 233.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 389.11 233.25 Td (gain ) Tj ET Q q 0 0 0 rg BT 409.19 233.25 Td (ar) Tj ET Q q 0 0 0 rg BT 417.71 233.25 Td (e ) Tj ET Q q 0 0 0 rg BT 424.45 233.25 Td (also ) Tj ET Q q 0 0 0 rg BT 443.42 233.25 Td (incr) Tj ET Q q 0 0 0 rg BT 459.15 233.25 Td (easingly ) Tj ET Q q 0 0 0 rg BT 494.78 233.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 527.06 233.25 Td (to ) Tj ET Q q 0 0 0 rg BT 537.14 233.25 Td (challenge ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 221.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 67.45 221.25 Td (befor) Tj ET Q q 0 0 0 rg BT 88.19 221.25 Td (e ) Tj ET Q q 0 0 0 rg BT 95.19 221.25 Td (they ) Tj ET Q q 0 0 0 rg BT 114.41 221.25 Td (expir) Tj ET Q q 0 0 0 rg BT 134.58 221.25 Td (e, ) Tj ET Q q 0 0 0 rg BT 144.09 221.25 Td (and ) Tj ET Q q 0 0 0 rg BT 161.65 221.25 Td (we ) Tj ET Q q 0 0 0 rg BT 175.32 221.25 Td (could ) Tj ET Q q 0 0 0 rg BT 200.10 221.25 Td (face ) Tj ET Q q 0 0 0 rg BT 219.32 221.25 Td (earlier) Tj ET Q q 0 0 0 rg BT 246.34 221.25 Td (-than-expected ) Tj ET Q q 0 0 0 rg BT 308.31 221.25 Td (competition ) Tj ET Q q 0 0 0 rg BT 358.08 221.25 Td (for ) Tj ET Q q 0 0 0 rg BT 372.32 221.25 Td (any ) Tj ET Q q 0 0 0 rg BT 389.32 221.25 Td (pr) Tj ET Q q 0 0 0 rg BT 397.84 221.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 426.51 221.25 Td (at ) Tj ET Q q 0 0 0 rg BT 436.85 221.25 Td (any ) Tj ET Q q 0 0 0 rg BT 453.86 221.25 Td (time. ) Tj ET Q q 0 0 0 rg BT 476.14 221.25 Td (Patents ) Tj ET Q q 0 0 0 rg BT 508.70 221.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 546.24 221.25 Td (our ) Tj ET Q q 0 0 0 rg BT 562.70 221.25 Td (key ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 209.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 209.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 73.25 209.25 Td (have ) Tj ET Q q 0 0 0 rg BT 94.75 209.25 Td (been, ) Tj ET Q q 0 0 0 rg BT 118.75 209.25 Td (and ) Tj ET Q q 0 0 0 rg BT 136.37 209.25 Td (ar) Tj ET Q q 0 0 0 rg BT 144.89 209.25 Td (e ) Tj ET Q q 0 0 0 rg BT 151.95 209.25 Td (likely ) Tj ET Q q 0 0 0 rg BT 176.22 209.25 Td (to ) Tj ET Q q 0 0 0 rg BT 186.63 209.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 223.68 209.25 Td (to ) Tj ET Q q 0 0 0 rg BT 234.08 209.25 Td (be, ) Tj ET Q q 0 0 0 rg BT 248.64 209.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 279.59 209.25 Td (to ) Tj ET Q q 0 0 0 rg BT 289.99 209.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 317.61 209.25 Td (litigation. ) Tj ET Q q 0 0 0 rg BT 359.40 209.25 Td (For ) Tj ET Q q 0 0 0 rg BT 377.02 209.25 Td (example, ) Tj ET Q q 0 0 0 rg BT 415.46 209.25 Td (in ) Tj ET Q q 0 0 0 rg BT 425.86 209.25 Td (February ) Tj ET Q q 0 0 0 rg BT 466.25 209.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 488.87 209.25 Td (one ) Tj ET Q q 0 0 0 rg BT 505.93 209.25 Td (of ) Tj ET Q q 0 0 0 rg BT 516.33 209.25 Td (the ) Tj ET Q q 0 0 0 rg BT 531.17 209.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 547.12 209.25 Td (patents ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 197.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.46 197.25 Td (Sprycel ) Tj ET Q q 0 0 0 rg BT 83.23 197.25 Td (was ) Tj ET Q q 0 0 0 rg BT 101.59 197.25 Td (r) Tj ET Q q 0 0 0 rg BT 105.11 197.25 Td (evoked ) Tj ET Q q 0 0 0 rg BT 135.65 197.25 Td (by ) Tj ET Q q 0 0 0 rg BT 147.88 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 162.88 197.25 Td (Opposition ) Tj ET Q q 0 0 0 rg BT 210.12 197.25 Td (Division ) Tj ET Q q 0 0 0 rg BT 246.80 197.25 Td (of ) Tj ET Q q 0 0 0 rg BT 257.37 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 272.37 197.25 Td (EPO. ) Tj ET Q q 0 0 0 rg BT 297.10 197.25 Td (W) Tj ET Q q 0 0 0 rg BT 304.51 197.25 Td (e ) Tj ET Q q 0 0 0 rg BT 311.74 197.25 Td (may ) Tj ET Q q 0 0 0 rg BT 331.19 197.25 Td (experience ) Tj ET Q q 0 0 0 rg BT 377.28 197.25 Td (a ) Tj ET Q q 0 0 0 rg BT 385.07 197.25 Td (decline ) Tj ET Q q 0 0 0 rg BT 416.73 197.25 Td (in ) Tj ET Q q 0 0 0 rg BT 427.30 197.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 441.93 197.25 Td (opean ) Tj ET Q q 0 0 0 rg BT 469.16 197.25 Td (r) Tj ET Q q 0 0 0 rg BT 472.68 197.25 Td (evenues ) Tj ET Q q 0 0 0 rg BT 507.11 197.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 529.90 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 544.91 197.25 Td (entry ) Tj ET Q q 0 0 0 rg BT 568.24 197.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 185.25 Td (generics ) Tj ET Q q 0 0 0 rg BT 71.57 185.25 Td (into ) Tj ET Q q 0 0 0 rg BT 88.81 185.25 Td (the ) Tj ET Q q 0 0 0 rg BT 102.72 185.25 Td (market. ) Tj ET Q q 0 0 0 rg BT 134.68 185.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 158.02 185.25 Td (to ) Tj ET Q q 0 0 0 rg BT 167.49 185.25 Td ("Item ) Tj ET Q q 0 0 0 rg BT 191.15 185.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 200.34 185.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 240.91 185.25 Td (Statements—Note ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 313.70 185.25 Td (18) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 323.70 185.25 Td (. ) Tj ET Q q 0 0 0 rg BT 327.89 185.25 Td (Legal ) Tj ET Q q 0 0 0 rg BT 352.36 185.25 Td (Pr) Tj ET Q q 0 0 0 rg BT 361.99 185.25 Td (oceedings ) Tj ET Q q 0 0 0 rg BT 403.66 185.25 Td (and ) Tj ET Q q 0 0 0 rg BT 420.35 185.25 Td (Contingencies" ) Tj ET Q q 0 0 0 rg BT 483.45 185.25 Td (for ) Tj ET Q q 0 0 0 rg BT 496.81 185.25 Td (further ) Tj ET Q q 0 0 0 rg BT 526.28 185.25 Td (information. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 173.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.59 173.25 Td (some ) Tj ET Q q 0 0 0 rg BT 69.40 173.25 Td (cases, ) Tj ET Q q 0 0 0 rg BT 95.82 173.25 Td (manufactur) Tj ET Q q 0 0 0 rg BT 141.56 173.25 Td (ers ) Tj ET Q q 0 0 0 rg BT 156.04 173.25 Td (may ) Tj ET Q q 0 0 0 rg BT 174.96 173.25 Td (seek ) Tj ET Q q 0 0 0 rg BT 194.43 173.25 Td (r) Tj ET Q q 0 0 0 rg BT 197.95 173.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 238.54 173.25 Td (appr) Tj ET Q q 0 0 0 rg BT 257.06 173.25 Td (oval ) Tj ET Q q 0 0 0 rg BT 276.54 173.25 Td (by ) Tj ET Q q 0 0 0 rg BT 288.24 173.25 Td (submitting ) Tj ET Q q 0 0 0 rg BT 332.72 173.25 Td (their ) Tj ET Q q 0 0 0 rg BT 353.87 173.25 Td (own ) Tj ET Q q 0 0 0 rg BT 372.80 173.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 405.05 173.25 Td (study ) Tj ET Q q 0 0 0 rg BT 428.42 173.25 Td (data ) Tj ET Q q 0 0 0 rg BT 448.46 173.25 Td (to ) Tj ET Q q 0 0 0 rg BT 458.50 173.25 Td (obtain ) Tj ET Q q 0 0 0 rg BT 486.32 173.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 529.13 173.25 Td (appr) Tj ET Q q 0 0 0 rg BT 547.65 173.25 Td (oval ) Tj ET Q q 0 0 0 rg BT 567.12 173.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 161.25 Td (choose ) Tj ET Q q 0 0 0 rg BT 65.82 161.25 Td (to ) Tj ET Q q 0 0 0 rg BT 75.65 161.25 Td (launch ) Tj ET Q q 0 0 0 rg BT 104.91 161.25 Td (a ) Tj ET Q q 0 0 0 rg BT 111.96 161.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 144.00 161.25 Td (pr) Tj ET Q q 0 0 0 rg BT 152.52 161.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 176.79 161.25 Td (“at ) Tj ET Q q 0 0 0 rg BT 192.17 161.25 Td (risk” ) Tj ET Q q 0 0 0 rg BT 214.79 161.25 Td (befor) Tj ET Q q 0 0 0 rg BT 235.52 161.25 Td (e ) Tj ET Q q 0 0 0 rg BT 242.01 161.25 Td (the ) Tj ET Q q 0 0 0 rg BT 256.28 161.25 Td (expiration ) Tj ET Q q 0 0 0 rg BT 299.43 161.25 Td (of ) Tj ET Q q 0 0 0 rg BT 309.26 161.25 Td (the ) Tj ET Q q 0 0 0 rg BT 323.53 161.25 Td (applicable ) Tj ET Q q 0 0 0 rg BT 367.79 161.25 Td (patent\(s\) ) Tj ET Q q 0 0 0 rg BT 405.38 161.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 434.10 161.25 Td (befor) Tj ET Q q 0 0 0 rg BT 454.84 161.25 Td (e ) Tj ET Q q 0 0 0 rg BT 461.33 161.25 Td (the ) Tj ET Q q 0 0 0 rg BT 475.60 161.25 Td (final ) Tj ET Q q 0 0 0 rg BT 495.98 161.25 Td (r) Tj ET Q q 0 0 0 rg BT 499.50 161.25 Td (esolution ) Tj ET Q q 0 0 0 rg BT 538.22 161.25 Td (of ) Tj ET Q q 0 0 0 rg BT 548.04 161.25 Td (r) Tj ET Q q 0 0 0 rg BT 551.57 161.25 Td (elated ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 149.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 63.22 149.25 Td (litigation. ) Tj ET Q q 0 0 0 rg BT 104.61 149.25 Td (Ther) Tj ET Q q 0 0 0 rg BT 123.13 149.25 Td (e ) Tj ET Q q 0 0 0 rg BT 129.79 149.25 Td (is ) Tj ET Q q 0 0 0 rg BT 138.68 149.25 Td (no ) Tj ET Q q 0 0 0 rg BT 150.90 149.25 Td (assurance ) Tj ET Q q 0 0 0 rg BT 193.68 149.25 Td (that ) Tj ET Q q 0 0 0 rg BT 211.45 149.25 Td (a ) Tj ET Q q 0 0 0 rg BT 218.68 149.25 Td (particular ) Tj ET Q q 0 0 0 rg BT 261.45 149.25 Td (pr) Tj ET Q q 0 0 0 rg BT 269.97 149.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 294.41 149.25 Td (will ) Tj ET Q q 0 0 0 rg BT 311.64 149.25 Td (enjoy ) Tj ET Q q 0 0 0 rg BT 335.52 149.25 Td (market ) Tj ET Q q 0 0 0 rg BT 365.51 149.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 409.93 149.25 Td (for ) Tj ET Q q 0 0 0 rg BT 423.82 149.25 Td (the ) Tj ET Q q 0 0 0 rg BT 438.26 149.25 Td (full ) Tj ET Q q 0 0 0 rg BT 453.81 149.25 Td (time ) Tj ET Q q 0 0 0 rg BT 473.25 149.25 Td (period ) Tj ET Q q 0 0 0 rg BT 501.58 149.25 Td (that ) Tj ET Q q 0 0 0 rg BT 519.36 149.25 Td (appears ) Tj ET Q q 0 0 0 rg BT 553.80 149.25 Td (in ) Tj ET Q q 0 0 0 rg BT 563.80 149.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 137.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 75.76 137.25 Td (disclosed ) Tj ET Q q 0 0 0 rg BT 115.53 137.25 Td (in ) Tj ET Q q 0 0 0 rg BT 125.85 137.25 Td (this ) Tj ET Q q 0 0 0 rg BT 142.85 137.25 Td (Form ) Tj ET Q q 0 0 0 rg BT 167.61 137.25 Td (10-K ) Tj ET Q q 0 0 0 rg BT 190.16 137.25 Td (or ) Tj ET Q q 0 0 0 rg BT 201.60 137.25 Td (that ) Tj ET Q q 0 0 0 rg BT 219.70 137.25 Td (we ) Tj ET Q q 0 0 0 rg BT 233.36 137.25 Td (assume ) Tj ET Q q 0 0 0 rg BT 265.35 137.25 Td (when ) Tj ET Q q 0 0 0 rg BT 289.00 137.25 Td (we ) Tj ET Q q 0 0 0 rg BT 302.66 137.25 Td (pr) Tj ET Q q 0 0 0 rg BT 311.18 137.25 Td (ovide ) Tj ET Q q 0 0 0 rg BT 335.38 137.25 Td (our ) Tj ET Q q 0 0 0 rg BT 351.82 137.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 389.91 137.25 Td (guidance. ) Tj ET Q q 0 0 0 rg BT 431.62 137.25 Td (In ) Tj ET Q q 0 0 0 rg BT 442.49 137.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 480.87 137.25 Td (some ) Tj ET Q q 0 0 0 rg BT 503.97 137.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 546.23 137.25 Td (such ) Tj ET Q q 0 0 0 rg BT 567.11 137.25 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 125.25 Td (India, ) Tj ET Q q 0 0 0 rg BT 62.06 125.25 Td (ar) Tj ET Q q 0 0 0 rg BT 70.58 125.25 Td (e ) Tj ET Q q 0 0 0 rg BT 77.46 125.25 Td (allowing ) Tj ET Q q 0 0 0 rg BT 114.92 125.25 Td (competitors ) Tj ET Q q 0 0 0 rg BT 164.58 125.25 Td (to ) Tj ET Q q 0 0 0 rg BT 174.81 125.25 Td (manufactur) Tj ET Q q 0 0 0 rg BT 220.54 125.25 Td (e ) Tj ET Q q 0 0 0 rg BT 227.43 125.25 Td (and ) Tj ET Q q 0 0 0 rg BT 244.88 125.25 Td (sell ) Tj ET Q q 0 0 0 rg BT 261.21 125.25 Td (competing ) Tj ET Q q 0 0 0 rg BT 305.31 125.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 337.75 125.25 Td (pr) Tj ET Q q 0 0 0 rg BT 346.27 125.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 377.32 125.25 Td (which ) Tj ET Q q 0 0 0 rg BT 403.66 125.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 447.20 125.25 Td (impacts ) Tj ET Q q 0 0 0 rg BT 480.75 125.25 Td (the ) Tj ET Q q 0 0 0 rg BT 495.42 125.25 Td (pr) Tj ET Q q 0 0 0 rg BT 503.94 125.25 Td (otections ) Tj ET Q q 0 0 0 rg BT 542.49 125.25 Td (affor) Tj ET Q q 0 0 0 rg BT 561.57 125.25 Td (ded ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 113.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.36 113.25 Td (Company) Tj ET Q q 0 0 0 rg BT 89.14 113.25 Td (. ) Tj ET Q q 0 0 0 rg BT 94.79 113.25 Td (Lower) Tj ET Q q 0 0 0 rg BT 120.15 113.25 Td (-priced ) Tj ET Q q 0 0 0 rg BT 152.17 113.25 Td (biosimilars ) Tj ET Q q 0 0 0 rg BT 200.33 113.25 Td (for ) Tj ET Q q 0 0 0 rg BT 215.15 113.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 237.73 113.25 Td (biologic ) Tj ET Q q 0 0 0 rg BT 273.65 113.25 Td (pr) Tj ET Q q 0 0 0 rg BT 282.17 113.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 311.43 113.25 Td (or ) Tj ET Q q 0 0 0 rg BT 323.47 113.25 Td (competing ) Tj ET Q q 0 0 0 rg BT 368.27 113.25 Td (biologics ) Tj ET Q q 0 0 0 rg BT 408.08 113.25 Td (could ) Tj ET Q q 0 0 0 rg BT 433.45 113.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 477.68 113.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 508.05 113.25 Td (our ) Tj ET Q q 0 0 0 rg BT 525.08 113.25 Td (volumes ) Tj ET Q q 0 0 0 rg BT 561.00 113.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 101.25 Td (prices.) Tj ET Q endstream endobj 43 0 obj <> endobj 44 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (21) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Increased ) Tj ET Q q 0 0 0 rg BT 80.09 749.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 113.07 749.25 Td (pressure ) Tj ET Q q 0 0 0 rg BT 151.61 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.71 749.25 Td (other ) Tj ET Q q 0 0 0 rg BT 195.92 749.25 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 245.57 749.25 Td (in ) Tj ET Q q 0 0 0 rg BT 257.45 749.25 Td (the ) Tj ET Q q 0 0 0 rg BT 273.77 749.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 295.09 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 314.18 749.25 Td (abroad ) Tj ET Q q 0 0 0 rg BT 346.61 749.25 Td (from ) Tj ET Q q 0 0 0 rg BT 370.15 749.25 Td (MCOs, ) Tj ET Q q 0 0 0 rg BT 402.86 749.25 Td (institutional ) Tj ET Q q 0 0 0 rg BT 456.42 749.25 Td (purchasers, ) Tj ET Q q 0 0 0 rg BT 508.02 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 527.12 749.25 Td (government ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (agencies ) Tj ET Q q 0 0 0 rg BT 74.05 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 92.11 737.25 Td (programs, ) Tj ET Q q 0 0 0 rg BT 136.56 737.25 Td (among ) Tj ET Q q 0 0 0 rg BT 167.40 737.25 Td (others, ) Tj ET Q q 0 0 0 rg BT 197.96 737.25 Td (could ) Tj ET Q q 0 0 0 rg BT 223.24 737.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 267.39 737.25 Td (af) Tj ET Q q 0 0 0 rg BT 275.54 737.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 293.03 737.25 Td (our ) Tj ET Q q 0 0 0 rg BT 309.98 737.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 349.14 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 367.20 737.25 Td (profit ) Tj ET Q q 0 0 0 rg BT 392.48 737.25 Td (margins.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.62 725.25 Td (pr) Tj ET Q q 0 0 0 rg BT 63.14 725.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 91.75 725.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 128.69 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 138.97 725.25 Td (be ) Tj ET Q q 0 0 0 rg BT 150.91 725.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 181.74 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 192.02 725.25 Td (incr) Tj ET Q q 0 0 0 rg BT 207.76 725.25 Td (easing ) Tj ET Q q 0 0 0 rg BT 236.37 725.25 Td (pr) Tj ET Q q 0 0 0 rg BT 244.89 725.25 Td (essur) Tj ET Q q 0 0 0 rg BT 265.64 725.25 Td (es ) Tj ET Q q 0 0 0 rg BT 276.47 725.25 Td (acr) Tj ET Q q 0 0 0 rg BT 289.43 725.25 Td (oss ) Tj ET Q q 0 0 0 rg BT 304.72 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 319.44 725.25 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 356.95 725.25 Td (fr) Tj ET Q q 0 0 0 rg BT 363.24 725.25 Td (om ) Tj ET Q q 0 0 0 rg BT 377.97 725.25 Td (market ) Tj ET Q q 0 0 0 rg BT 408.24 725.25 Td (access, ) Tj ET Q q 0 0 0 rg BT 439.34 725.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 470.74 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 488.24 725.25 Td (discounting ) Tj ET Q q 0 0 0 rg BT 537.41 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 554.91 725.25 Td (other ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 713.25 Td (estrictions ) Tj ET Q q 0 0 0 rg BT 83.33 713.25 Td (in ) Tj ET Q q 0 0 0 rg BT 93.26 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 107.63 713.25 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 129.50 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 143.86 713.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 159.34 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 176.49 713.25 Td (other ) Tj ET Q q 0 0 0 rg BT 199.75 713.25 Td (r) Tj ET Q q 0 0 0 rg BT 203.27 713.25 Td (egions ) Tj ET Q q 0 0 0 rg BT 231.52 713.25 Td (ar) Tj ET Q q 0 0 0 rg BT 240.04 713.25 Td (ound ) Tj ET Q q 0 0 0 rg BT 262.19 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 276.56 713.25 Td (world, ) Tj ET Q q 0 0 0 rg BT 304.54 713.25 Td (including ) Tj ET Q q 0 0 0 rg BT 344.47 713.25 Td (fr) Tj ET Q q 0 0 0 rg BT 350.77 713.25 Td (om ) Tj ET Q q 0 0 0 rg BT 365.14 713.25 Td (\(i\) rules ) Tj ET Q q 0 0 0 rg BT 399.22 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 416.37 713.25 Td (practices ) Tj ET Q q 0 0 0 rg BT 455.17 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 465.10 713.25 Td (MCOs ) Tj ET Q q 0 0 0 rg BT 493.36 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 510.51 713.25 Td (institutional ) Tj ET Q q 0 0 0 rg BT 561.00 713.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (governmental ) Tj ET Q q 0 0 0 rg BT 93.17 701.25 Td (pur) Tj ET Q q 0 0 0 rg BT 106.69 701.25 Td (chasers; ) Tj ET Q q 0 0 0 rg BT 142.76 701.25 Td (\(ii\) judicial ) Tj ET Q q 0 0 0 rg BT 190.22 701.25 Td (decisions ) Tj ET Q q 0 0 0 rg BT 229.62 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 246.81 701.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 281.76 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 291.73 701.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 312.25 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 329.44 701.25 Td (r) Tj ET Q q 0 0 0 rg BT 332.96 701.25 Td (egulations ) Tj ET Q q 0 0 0 rg BT 376.81 701.25 Td (for ) Tj ET Q q 0 0 0 rg BT 390.67 701.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 421.18 701.25 Td (healthcar) Tj ET Q q 0 0 0 rg BT 459.13 701.25 Td (e ) Tj ET Q q 0 0 0 rg BT 465.76 701.25 Td (pr) Tj ET Q q 0 0 0 rg BT 474.28 701.25 Td (ograms ) Tj ET Q q 0 0 0 rg BT 506.47 701.25 Td (such ) Tj ET Q q 0 0 0 rg BT 526.99 701.25 Td (as ) Tj ET Q q 0 0 0 rg BT 538.06 701.25 Td (Medicar) Tj ET Q q 0 0 0 rg BT 571.57 701.25 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.88 689.25 Td (Medicaid, ) Tj ET Q q 0 0 0 rg BT 95.02 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 111.90 689.25 Td (other ) Tj ET Q q 0 0 0 rg BT 134.89 689.25 Td (government ) Tj ET Q q 0 0 0 rg BT 183.97 689.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 214.74 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 231.62 689.25 Td (inquiries ) Tj ET Q q 0 0 0 rg BT 269.05 689.25 Td (at ) Tj ET Q q 0 0 0 rg BT 278.71 689.25 Td (both ) Tj ET Q q 0 0 0 rg BT 298.37 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 312.46 689.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 342.67 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 359.55 689.25 Td (state ) Tj ET Q q 0 0 0 rg BT 380.31 689.25 Td (level ) Tj ET Q q 0 0 0 rg BT 401.06 689.25 Td (such ) Tj ET Q q 0 0 0 rg BT 421.27 689.25 Td (as ) Tj ET Q q 0 0 0 rg BT 432.04 689.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 452.26 689.25 Td (that ) Tj ET Q q 0 0 0 rg BT 469.70 689.25 Td (have ) Tj ET Q q 0 0 0 rg BT 490.45 689.25 Td (r) Tj ET Q q 0 0 0 rg BT 493.97 689.25 Td (ecently ) Tj ET Q q 0 0 0 rg BT 524.16 689.25 Td (been ) Tj ET Q q 0 0 0 rg BT 544.92 689.25 Td (enacted ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.56 677.25 Td (California, ) Tj ET Q q 0 0 0 rg BT 93.51 677.25 Td (V) Tj ET Q q 0 0 0 rg BT 98.51 677.25 Td (ermont, ) Tj ET Q q 0 0 0 rg BT 132.12 677.25 Td (Nevada ) Tj ET Q q 0 0 0 rg BT 165.44 677.25 Td (and ) Tj ET Q q 0 0 0 rg BT 183.22 677.25 Td (New ) Tj ET Q q 0 0 0 rg BT 203.78 677.25 Td (Y) Tj ET Q q 0 0 0 rg BT 208.42 677.25 Td (ork ) Tj ET Q q 0 0 0 rg BT 224.53 677.25 Td (that ) Tj ET Q q 0 0 0 rg BT 242.87 677.25 Td (ar) Tj ET Q q 0 0 0 rg BT 251.39 677.25 Td (e ) Tj ET Q q 0 0 0 rg BT 258.60 677.25 Td (focused ) Tj ET Q q 0 0 0 rg BT 291.93 677.25 Td (on ) Tj ET Q q 0 0 0 rg BT 304.71 677.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 326.38 677.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 358.04 677.25 Td (transpar) Tj ET Q q 0 0 0 rg BT 392.12 677.25 Td (ency ) Tj ET Q q 0 0 0 rg BT 413.22 677.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 442.67 677.25 Td (limiting ) Tj ET Q q 0 0 0 rg BT 476.56 677.25 Td (state ) Tj ET Q q 0 0 0 rg BT 498.22 677.25 Td (spending ) Tj ET Q q 0 0 0 rg BT 537.11 677.25 Td (on ) Tj ET Q q 0 0 0 rg BT 549.89 677.25 Td (drugs; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (\(iii\) the ) Tj ET Q q 0 0 0 rg BT 67.44 665.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 104.71 665.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 133.65 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 143.15 665.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 177.65 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 187.15 665.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 251.63 665.25 Td (r) Tj ET Q q 0 0 0 rg BT 255.16 665.25 Td (eimbursement, ) Tj ET Q q 0 0 0 rg BT 315.48 665.25 Td (and ) Tj ET Q q 0 0 0 rg BT 332.20 665.25 Td (incr) Tj ET Q q 0 0 0 rg BT 347.94 665.25 Td (eased ) Tj ET Q q 0 0 0 rg BT 372.43 665.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 403.04 665.25 Td (pr) Tj ET Q q 0 0 0 rg BT 411.56 665.25 Td (essur) Tj ET Q q 0 0 0 rg BT 432.30 665.25 Td (e ) Tj ET Q q 0 0 0 rg BT 438.47 665.25 Td (fr) Tj ET Q q 0 0 0 rg BT 444.76 665.25 Td (om ) Tj ET Q q 0 0 0 rg BT 458.71 665.25 Td (Medicar) Tj ET Q q 0 0 0 rg BT 492.22 665.25 Td (e ) Tj ET Q q 0 0 0 rg BT 498.38 665.25 Td (Part ) Tj ET Q q 0 0 0 rg BT 517.88 665.25 Td (D ) Tj ET Q q 0 0 0 rg BT 526.83 665.25 Td (formularies, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (Medicar) Tj ET Q q 0 0 0 rg BT 69.51 653.25 Td (e ) Tj ET Q q 0 0 0 rg BT 78.88 653.25 Td (Part ) Tj ET Q q 0 0 0 rg BT 101.60 653.25 Td (B ) Tj ET Q q 0 0 0 rg BT 112.65 653.25 Td (r) Tj ET Q q 0 0 0 rg BT 116.17 653.25 Td (eimbursement ) Tj ET Q q 0 0 0 rg BT 177.20 653.25 Td (rates ) Tj ET Q q 0 0 0 rg BT 202.14 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 214.86 653.25 Td (physicians ) Tj ET Q q 0 0 0 rg BT 262.01 653.25 Td (as ) Tj ET Q q 0 0 0 rg BT 275.84 653.25 Td (well ) Tj ET Q q 0 0 0 rg BT 297.44 653.25 Td (as ) Tj ET Q q 0 0 0 rg BT 311.27 653.25 Td (commer) Tj ET Q q 0 0 0 rg BT 343.11 653.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 363.05 653.25 Td (formularies ) Tj ET Q q 0 0 0 rg BT 414.66 653.25 Td (in ) Tj ET Q q 0 0 0 rg BT 427.37 653.25 Td (general; ) Tj ET Q q 0 0 0 rg BT 466.19 653.25 Td (\(iv\) r) Tj ET Q q 0 0 0 rg BT 486.08 653.25 Td (eimbursement ) Tj ET Q q 0 0 0 rg BT 547.12 653.25 Td (delays; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (\(v\) government ) Tj ET Q q 0 0 0 rg BT 98.42 641.25 Td (price ) Tj ET Q q 0 0 0 rg BT 120.58 641.25 Td (er) Tj ET Q q 0 0 0 rg BT 128.54 641.25 Td (osion ) Tj ET Q q 0 0 0 rg BT 151.82 641.25 Td (mechanisms ) Tj ET Q q 0 0 0 rg BT 202.32 641.25 Td (acr) Tj ET Q q 0 0 0 rg BT 215.28 641.25 Td (oss ) Tj ET Q q 0 0 0 rg BT 229.67 641.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 244.30 641.25 Td (ope ) Tj ET Q q 0 0 0 rg BT 260.36 641.25 Td (and ) Tj ET Q q 0 0 0 rg BT 276.97 641.25 Td (in ) Tj ET Q q 0 0 0 rg BT 286.36 641.25 Td (other ) Tj ET Q q 0 0 0 rg BT 309.08 641.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 350.41 641.25 Td (r) Tj ET Q q 0 0 0 rg BT 353.93 641.25 Td (esulting ) Tj ET Q q 0 0 0 rg BT 387.21 641.25 Td (in ) Tj ET Q q 0 0 0 rg BT 396.61 641.25 Td (deflation ) Tj ET Q q 0 0 0 rg BT 433.77 641.25 Td (for ) Tj ET Q q 0 0 0 rg BT 447.05 641.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 511.43 641.25 Td (pr) Tj ET Q q 0 0 0 rg BT 519.95 641.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 543.78 641.25 Td (pricing; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (\(vi\) collection ) Tj ET Q q 0 0 0 rg BT 94.29 629.25 Td (delays ) Tj ET Q q 0 0 0 rg BT 122.32 629.25 Td (or ) Tj ET Q q 0 0 0 rg BT 133.70 629.25 Td (failur) Tj ET Q q 0 0 0 rg BT 155.56 629.25 Td (es ) Tj ET Q q 0 0 0 rg BT 166.37 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 176.63 629.25 Td (pay ) Tj ET Q q 0 0 0 rg BT 193.56 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 203.82 629.25 Td (government-funded ) Tj ET Q q 0 0 0 rg BT 284.06 629.25 Td (public ) Tj ET Q q 0 0 0 rg BT 311.54 629.25 Td (hospitals ) Tj ET Q q 0 0 0 rg BT 350.15 629.25 Td (outside ) Tj ET Q q 0 0 0 rg BT 381.52 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 396.22 629.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 415.93 629.25 Td (\(vii\) ) Tj ET Q q 0 0 0 rg BT 435.07 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 449.77 629.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 479.47 629.25 Td (on ) Tj ET Q q 0 0 0 rg BT 491.96 629.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 523.33 629.25 Td (fr) Tj ET Q q 0 0 0 rg BT 529.63 629.25 Td (om ) Tj ET Q q 0 0 0 rg BT 544.33 629.25 Td (parallel ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (trade ) Tj ET Q q 0 0 0 rg BT 60.14 617.25 Td (acr) Tj ET Q q 0 0 0 rg BT 73.09 617.25 Td (oss ) Tj ET Q q 0 0 0 rg BT 88.91 617.25 Td (bor) Tj ET Q q 0 0 0 rg BT 102.43 617.25 Td (ders; ) Tj ET Q q 0 0 0 rg BT 126.00 617.25 Td (\(viii\) ) Tj ET Q q 0 0 0 rg BT 148.47 617.25 Td (other ) Tj ET Q q 0 0 0 rg BT 172.60 617.25 Td (developments ) Tj ET Q q 0 0 0 rg BT 230.05 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 240.86 617.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 287.76 617.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 317.46 617.25 Td (industry ) Tj ET Q q 0 0 0 rg BT 353.26 617.25 Td (practices ) Tj ET Q q 0 0 0 rg BT 392.94 617.25 Td (that ) Tj ET Q q 0 0 0 rg BT 411.53 617.25 Td (could ) Tj ET Q q 0 0 0 rg BT 436.77 617.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 467.02 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 482.26 617.25 Td (r) Tj ET Q q 0 0 0 rg BT 485.78 617.25 Td (eimbursement ) Tj ET Q q 0 0 0 rg BT 544.91 617.25 Td (policies ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.78 605.25 Td (practices ) Tj ET Q q 0 0 0 rg BT 93.21 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 103.77 605.25 Td (thir) Tj ET Q q 0 0 0 rg BT 117.85 605.25 Td (d-party ) Tj ET Q q 0 0 0 rg BT 150.06 605.25 Td (payers; ) Tj ET Q q 0 0 0 rg BT 182.83 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 200.61 605.25 Td (\(ix\) inhibited ) Tj ET Q q 0 0 0 rg BT 255.32 605.25 Td (market ) Tj ET Q q 0 0 0 rg BT 285.86 605.25 Td (access ) Tj ET Q q 0 0 0 rg BT 314.74 605.25 Td (due ) Tj ET Q q 0 0 0 rg BT 331.96 605.25 Td (to ) Tj ET Q q 0 0 0 rg BT 342.51 605.25 Td (r) Tj ET Q q 0 0 0 rg BT 346.03 605.25 Td (eal ) Tj ET Q q 0 0 0 rg BT 361.03 605.25 Td (or ) Tj ET Q q 0 0 0 rg BT 372.70 605.25 Td (per) Tj ET Q q 0 0 0 rg BT 385.66 605.25 Td (ceived ) Tj ET Q q 0 0 0 rg BT 413.97 605.25 Td (differ) Tj ET Q q 0 0 0 rg BT 435.26 605.25 Td (ences ) Tj ET Q q 0 0 0 rg BT 460.25 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 470.80 605.25 Td (value ) Tj ET Q q 0 0 0 rg BT 495.24 605.25 Td (pr) Tj ET Q q 0 0 0 rg BT 503.76 605.25 Td (opositions ) Tj ET Q q 0 0 0 rg BT 547.66 605.25 Td (for ) Tj ET Q q 0 0 0 rg BT 562.10 605.25 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 593.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 73.13 593.25 Td (compar) Tj ET Q q 0 0 0 rg BT 103.31 593.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 115.25 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 125.53 593.25 Td (competing ) Tj ET Q q 0 0 0 rg BT 169.68 593.25 Td (pr) Tj ET Q q 0 0 0 rg BT 178.20 593.25 Td (oducts.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 569.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.09 569.25 Td (are ) Tj ET Q q 0 0 0 rg BT 66.92 569.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 98.30 569.25 Td (to ) Tj ET Q q 0 0 0 rg BT 108.58 569.25 Td (a ) Tj ET Q q 0 0 0 rg BT 116.08 569.25 Td (variety ) Tj ET Q q 0 0 0 rg BT 146.35 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 157.18 569.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 177.46 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 195.52 569.25 Td (international ) Tj ET Q q 0 0 0 rg BT 251.93 569.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 272.77 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 290.83 569.25 Td (regulations.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 557.25 Td (e ) Tj ET Q q 0 0 0 rg BT 50.74 557.25 Td (ar) Tj ET Q q 0 0 0 rg BT 59.26 557.25 Td (e ) Tj ET Q q 0 0 0 rg BT 66.58 557.25 Td (curr) Tj ET Q q 0 0 0 rg BT 83.43 557.25 Td (ently ) Tj ET Q q 0 0 0 rg BT 105.75 557.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 136.96 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 147.62 557.25 Td (a ) Tj ET Q q 0 0 0 rg BT 155.51 557.25 Td (number ) Tj ET Q q 0 0 0 rg BT 188.94 557.25 Td (of ) Tj ET Q q 0 0 0 rg BT 199.61 557.25 Td (government ) Tj ET Q q 0 0 0 rg BT 249.70 557.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 270.92 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 288.81 557.25 Td (r) Tj ET Q q 0 0 0 rg BT 292.33 557.25 Td (egulations ) Tj ET Q q 0 0 0 rg BT 336.88 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 354.76 557.25 Td (in ) Tj ET Q q 0 0 0 rg BT 365.42 557.25 Td (the ) Tj ET Q q 0 0 0 rg BT 380.53 557.25 Td (futur) Tj ET Q q 0 0 0 rg BT 399.60 557.25 Td (e, ) Tj ET Q q 0 0 0 rg BT 409.43 557.25 Td (could ) Tj ET Q q 0 0 0 rg BT 434.53 557.25 Td (become ) Tj ET Q q 0 0 0 rg BT 467.95 557.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 499.16 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 509.82 557.25 Td (new ) Tj ET Q q 0 0 0 rg BT 528.82 557.25 Td (government ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 56.29 545.25 Td (and ) Tj ET Q q 0 0 0 rg BT 73.24 545.25 Td (r) Tj ET Q q 0 0 0 rg BT 76.76 545.25 Td (egulations. ) Tj ET Q q 0 0 0 rg BT 122.87 545.25 Td (The ) Tj ET Q q 0 0 0 rg BT 139.82 545.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 161.77 545.25 Td (of ) Tj ET Q q 0 0 0 rg BT 171.49 545.25 Td (compliance ) Tj ET Q q 0 0 0 rg BT 219.54 545.25 Td (with ) Tj ET Q q 0 0 0 rg BT 238.71 545.25 Td (such ) Tj ET Q q 0 0 0 rg BT 258.99 545.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 279.28 545.25 Td (and ) Tj ET Q q 0 0 0 rg BT 296.22 545.25 Td (r) Tj ET Q q 0 0 0 rg BT 299.75 545.25 Td (egulations, ) Tj ET Q q 0 0 0 rg BT 345.86 545.25 Td (or ) Tj ET Q q 0 0 0 rg BT 356.70 545.25 Td (the ) Tj ET Q q 0 0 0 rg BT 370.86 545.25 Td (negative ) Tj ET Q q 0 0 0 rg BT 406.68 545.25 Td (r) Tj ET Q q 0 0 0 rg BT 410.20 545.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 434.93 545.25 Td (of ) Tj ET Q q 0 0 0 rg BT 444.66 545.25 Td (non-compliance, ) Tj ET Q q 0 0 0 rg BT 513.53 545.25 Td (could ) Tj ET Q q 0 0 0 rg BT 537.69 545.25 Td (adversely ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 61.29 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 78.26 533.25 Td (business, ) Tj ET Q q 0 0 0 rg BT 117.72 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 134.69 533.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 176.65 533.25 Td (r) Tj ET Q q 0 0 0 rg BT 180.17 533.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 206.03 533.25 Td (and ) Tj ET Q q 0 0 0 rg BT 224.11 533.25 Td (the ) Tj ET Q q 0 0 0 rg BT 239.40 533.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 278.03 533.25 Td (condition ) Tj ET Q q 0 0 0 rg BT 318.88 533.25 Td (of ) Tj ET Q q 0 0 0 rg BT 329.73 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 346.70 533.25 Td (Company; ) Tj ET Q q 0 0 0 rg BT 391.43 533.25 Td (these ) Tj ET Q q 0 0 0 rg BT 415.06 533.25 Td (include ) Tj ET Q q 0 0 0 rg BT 447.57 533.25 Td (\(i\) additional ) Tj ET Q q 0 0 0 rg BT 503.70 533.25 Td (healthcar) Tj ET Q q 0 0 0 rg BT 541.65 533.25 Td (e ) Tj ET Q q 0 0 0 rg BT 549.16 533.25 Td (r) Tj ET Q q 0 0 0 rg BT 552.68 533.25 Td (eform ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (initiatives ) Tj ET Q q 0 0 0 rg BT 77.90 521.25 Td (in ) Tj ET Q q 0 0 0 rg BT 88.14 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 102.82 521.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 122.51 521.25 Td (or ) Tj ET Q q 0 0 0 rg BT 133.86 521.25 Td (in ) Tj ET Q q 0 0 0 rg BT 144.11 521.25 Td (other ) Tj ET Q q 0 0 0 rg BT 167.68 521.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 209.86 521.25 Td (including ) Tj ET Q q 0 0 0 rg BT 250.09 521.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 293.67 521.25 Td (mandatory ) Tj ET Q q 0 0 0 rg BT 339.46 521.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 379.71 521.25 Td (or ) Tj ET Q q 0 0 0 rg BT 391.06 521.25 Td (fees; ) Tj ET Q q 0 0 0 rg BT 412.40 521.25 Td (\(ii\) new ) Tj ET Q q 0 0 0 rg BT 445.69 521.25 Td (laws, ) Tj ET Q q 0 0 0 rg BT 468.99 521.25 Td (r) Tj ET Q q 0 0 0 rg BT 472.51 521.25 Td (egulations ) Tj ET Q q 0 0 0 rg BT 516.64 521.25 Td (and ) Tj ET Q q 0 0 0 rg BT 534.11 521.25 Td (judicial ) Tj ET Q q 0 0 0 rg BT 567.12 521.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (other ) Tj ET Q q 0 0 0 rg BT 60.28 509.25 Td (governmental ) Tj ET Q q 0 0 0 rg BT 118.44 509.25 Td (decisions ) Tj ET Q q 0 0 0 rg BT 158.83 509.25 Td (affecting ) Tj ET Q q 0 0 0 rg BT 196.99 509.25 Td (pricing, ) Tj ET Q q 0 0 0 rg BT 231.55 509.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 253.62 509.25 Td (r) Tj ET Q q 0 0 0 rg BT 257.14 509.25 Td (eimbursement, ) Tj ET Q q 0 0 0 rg BT 318.91 509.25 Td (r) Tj ET Q q 0 0 0 rg BT 322.43 509.25 Td (eceivable ) Tj ET Q q 0 0 0 rg BT 363.35 509.25 Td (payments, ) Tj ET Q q 0 0 0 rg BT 406.79 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 424.96 509.25 Td (access ) Tj ET Q q 0 0 0 rg BT 454.24 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 466.30 509.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 510.02 509.25 Td (within ) Tj ET Q q 0 0 0 rg BT 538.20 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 550.26 509.25 Td (acr) Tj ET Q q 0 0 0 rg BT 563.22 509.25 Td (oss ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (jurisdictions; ) Tj ET Q q 0 0 0 rg BT 93.17 497.25 Td (\(iii\) changes ) Tj ET Q q 0 0 0 rg BT 147.27 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 158.88 497.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 207.71 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 216.23 497.25 Td (operty ) Tj ET Q q 0 0 0 rg BT 245.61 497.25 Td (law; ) Tj ET Q q 0 0 0 rg BT 267.22 497.25 Td (\(iv\) changes ) Tj ET Q q 0 0 0 rg BT 320.21 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 331.82 497.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 380.09 497.25 Td (standar) Tj ET Q q 0 0 0 rg BT 410.28 497.25 Td (ds; ) Tj ET Q q 0 0 0 rg BT 426.34 497.25 Td (\(v\) new ) Tj ET Q q 0 0 0 rg BT 459.88 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 478.72 497.25 Td (incr) Tj ET Q q 0 0 0 rg BT 494.45 497.25 Td (easing ) Tj ET Q q 0 0 0 rg BT 524.40 497.25 Td (data ) Tj ET Q q 0 0 0 rg BT 546.01 497.25 Td (privacy ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 485.25 Td (egulations ) Tj ET Q q 0 0 0 rg BT 83.96 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 101.73 485.25 Td (enfor) Tj ET Q q 0 0 0 rg BT 122.47 485.25 Td (cement, ) Tj ET Q q 0 0 0 rg BT 156.06 485.25 Td (particularly ) Tj ET Q q 0 0 0 rg BT 206.60 485.25 Td (in ) Tj ET Q q 0 0 0 rg BT 217.15 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 232.14 485.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 246.77 485.25 Td (opean ) Tj ET Q q 0 0 0 rg BT 273.98 485.25 Td (Union ) Tj ET Q q 0 0 0 rg BT 301.75 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 319.53 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 334.52 485.25 Td (U.S.; ) Tj ET Q q 0 0 0 rg BT 357.84 485.25 Td (\(vi\) emer) Tj ET Q q 0 0 0 rg BT 393.84 485.25 Td (ging ) Tj ET Q q 0 0 0 rg BT 414.39 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 432.16 485.25 Td (new ) Tj ET Q q 0 0 0 rg BT 451.04 485.25 Td (global ) Tj ET Q q 0 0 0 rg BT 479.37 485.25 Td (r) Tj ET Q q 0 0 0 rg BT 482.89 485.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 523.99 485.25 Td (r) Tj ET Q q 0 0 0 rg BT 527.51 485.25 Td (equir) Tj ET Q q 0 0 0 rg BT 548.25 485.25 Td (ements ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.26 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 53.78 473.25 Td (eporting ) Tj ET Q q 0 0 0 rg BT 90.26 473.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 130.62 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 148.21 473.25 Td (other ) Tj ET Q q 0 0 0 rg BT 171.91 473.25 Td (value ) Tj ET Q q 0 0 0 rg BT 196.15 473.25 Td (transfers ) Tj ET Q q 0 0 0 rg BT 234.30 473.25 Td (to ) Tj ET Q q 0 0 0 rg BT 244.67 473.25 Td (healthcar) Tj ET Q q 0 0 0 rg BT 282.63 473.25 Td (e ) Tj ET Q q 0 0 0 rg BT 289.65 473.25 Td (pr) Tj ET Q q 0 0 0 rg BT 298.18 473.25 Td (ofessionals; ) Tj ET Q q 0 0 0 rg BT 348.54 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 366.13 473.25 Td (\(vii\) ) Tj ET Q q 0 0 0 rg BT 385.38 473.25 Td (the ) Tj ET Q q 0 0 0 rg BT 400.19 473.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 438.33 473.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 468.14 473.25 Td (of ) Tj ET Q q 0 0 0 rg BT 478.50 473.25 Td (importation ) Tj ET Q q 0 0 0 rg BT 528.32 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 531.84 473.25 Td (estrictions, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (legislative ) Tj ET Q q 0 0 0 rg BT 79.60 461.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 108.77 461.25 Td (other ) Tj ET Q q 0 0 0 rg BT 132.38 461.25 Td (r) Tj ET Q q 0 0 0 rg BT 135.90 461.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 176.72 461.25 Td (changes.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 431.85 Td (Changes ) Tj ET Q q 0 0 0 rg BT 74.62 431.85 Td (to ) Tj ET Q q 0 0 0 rg BT 84.90 431.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 100.18 431.85 Td (regulations ) Tj ET Q q 0 0 0 rg BT 149.36 431.85 Td (could ) Tj ET Q q 0 0 0 rg BT 174.64 431.85 Td (negatively ) Tj ET Q q 0 0 0 rg BT 218.79 431.85 Td (impact ) Tj ET Q q 0 0 0 rg BT 249.06 431.85 Td (our ) Tj ET Q q 0 0 0 rg BT 266.01 431.85 Td (earnings.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 419.85 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 419.85 Td (e ) Tj ET Q q 0 0 0 rg BT 50.49 419.85 Td (ar) Tj ET Q q 0 0 0 rg BT 59.01 419.85 Td (e ) Tj ET Q q 0 0 0 rg BT 66.08 419.85 Td (subject ) Tj ET Q q 0 0 0 rg BT 97.04 419.85 Td (to ) Tj ET Q q 0 0 0 rg BT 107.46 419.85 Td (income ) Tj ET Q q 0 0 0 rg BT 138.97 419.85 Td (taxes ) Tj ET Q q 0 0 0 rg BT 162.15 419.85 Td (in ) Tj ET Q q 0 0 0 rg BT 172.57 419.85 Td (the ) Tj ET Q q 0 0 0 rg BT 187.42 419.85 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 207.28 419.85 Td (and ) Tj ET Q q 0 0 0 rg BT 224.91 419.85 Td (various ) Tj ET Q q 0 0 0 rg BT 257.55 419.85 Td (other ) Tj ET Q q 0 0 0 rg BT 281.29 419.85 Td (countries ) Tj ET Q q 0 0 0 rg BT 321.14 419.85 Td (globally) Tj ET Q q 0 0 0 rg BT 353.37 419.85 Td (. ) Tj ET Q q 0 0 0 rg BT 358.50 419.85 Td (In ) Tj ET Q q 0 0 0 rg BT 369.47 419.85 Td (particular) Tj ET Q q 0 0 0 rg BT 408.92 419.85 Td (, ) Tj ET Q q 0 0 0 rg BT 414.05 419.85 Td (although ) Tj ET Q q 0 0 0 rg BT 452.24 419.85 Td (the ) Tj ET Q q 0 0 0 rg BT 467.10 419.85 Td (passage ) Tj ET Q q 0 0 0 rg BT 501.95 419.85 Td (of ) Tj ET Q q 0 0 0 rg BT 512.37 419.85 Td (the ) Tj ET Q q 0 0 0 rg BT 527.22 419.85 Td (T) Tj ET Q q 0 0 0 rg BT 531.86 419.85 Td (ax ) Tj ET Q q 0 0 0 rg BT 543.94 419.85 Td (Cut ) Tj ET Q q 0 0 0 rg BT 561.02 419.85 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 407.85 Td (Jobs ) Tj ET Q q 0 0 0 rg BT 55.88 407.85 Td (Act ) Tj ET Q q 0 0 0 rg BT 70.88 407.85 Td (of ) Tj ET Q q 0 0 0 rg BT 80.33 407.85 Td (2017 ) Tj ET Q q 0 0 0 rg BT 102.01 407.85 Td (r) Tj ET Q q 0 0 0 rg BT 105.53 407.85 Td (educed ) Tj ET Q q 0 0 0 rg BT 135.52 407.85 Td (the ) Tj ET Q q 0 0 0 rg BT 149.41 407.85 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 168.30 407.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 182.19 407.85 Td (rate ) Tj ET Q q 0 0 0 rg BT 199.98 407.85 Td (to ) Tj ET Q q 0 0 0 rg BT 209.43 407.85 Td (21%, ) Tj ET Q q 0 0 0 rg BT 231.93 407.85 Td (our ) Tj ET Q q 0 0 0 rg BT 247.50 407.85 Td (futur) Tj ET Q q 0 0 0 rg BT 266.58 407.85 Td (e ) Tj ET Q q 0 0 0 rg BT 272.69 407.85 Td (earnings ) Tj ET Q q 0 0 0 rg BT 309.36 407.85 Td (could ) Tj ET Q q 0 0 0 rg BT 333.25 407.85 Td (be ) Tj ET Q q 0 0 0 rg BT 344.36 407.85 Td (negatively ) Tj ET Q q 0 0 0 rg BT 387.13 407.85 Td (impacted ) Tj ET Q q 0 0 0 rg BT 425.46 407.85 Td (by ) Tj ET Q q 0 0 0 rg BT 436.57 407.85 Td (changes ) Tj ET Q q 0 0 0 rg BT 471.01 407.85 Td (in ) Tj ET Q q 0 0 0 rg BT 480.46 407.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 494.35 407.85 Td (legislation ) Tj ET Q q 0 0 0 rg BT 538.25 407.85 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 395.85 Td (changing ) Tj ET Q q 0 0 0 rg BT 75.31 395.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 89.63 395.85 Td (rates ) Tj ET Q q 0 0 0 rg BT 111.73 395.85 Td (and ) Tj ET Q q 0 0 0 rg BT 128.82 395.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 143.14 395.85 Td (base ) Tj ET Q q 0 0 0 rg BT 163.56 395.85 Td (such ) Tj ET Q q 0 0 0 rg BT 183.99 395.85 Td (as ) Tj ET Q q 0 0 0 rg BT 194.98 395.85 Td (limiting, ) Tj ET Q q 0 0 0 rg BT 230.69 395.85 Td (phasing-out ) Tj ET Q q 0 0 0 rg BT 280.57 395.85 Td (or ) Tj ET Q q 0 0 0 rg BT 291.55 395.85 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 339.20 395.85 Td (deductions ) Tj ET Q q 0 0 0 rg BT 384.63 395.85 Td (or ) Tj ET Q q 0 0 0 rg BT 395.61 395.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 409.93 395.85 Td (cr) Tj ET Q q 0 0 0 rg BT 417.89 395.85 Td (edits, ) Tj ET Q q 0 0 0 rg BT 441.37 395.85 Td (taxing ) Tj ET Q q 0 0 0 rg BT 468.46 395.85 Td (certain ) Tj ET Q q 0 0 0 rg BT 498.89 395.85 Td (excess ) Tj ET Q q 0 0 0 rg BT 526.52 395.85 Td (income ) Tj ET Q q 0 0 0 rg BT 557.49 395.85 Td (fr) Tj ET Q q 0 0 0 rg BT 563.79 395.85 Td (om ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 383.85 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 83.40 383.85 Td (pr) Tj ET Q q 0 0 0 rg BT 91.92 383.85 Td (operty) Tj ET Q q 0 0 0 rg BT 116.92 383.85 Td (, ) Tj ET Q q 0 0 0 rg BT 121.83 383.85 Td (changing ) Tj ET Q q 0 0 0 rg BT 161.46 383.85 Td (rules ) Tj ET Q q 0 0 0 rg BT 183.88 383.85 Td (for ) Tj ET Q q 0 0 0 rg BT 197.96 383.85 Td (earnings ) Tj ET Q q 0 0 0 rg BT 235.38 383.85 Td (r) Tj ET Q q 0 0 0 rg BT 238.90 383.85 Td (epatriations ) Tj ET Q q 0 0 0 rg BT 289.65 383.85 Td (and ) Tj ET Q q 0 0 0 rg BT 307.06 383.85 Td (changing ) Tj ET Q q 0 0 0 rg BT 346.69 383.85 Td (other ) Tj ET Q q 0 0 0 rg BT 370.21 383.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 384.85 383.85 Td (laws ) Tj ET Q q 0 0 0 rg BT 405.60 383.85 Td (in ) Tj ET Q q 0 0 0 rg BT 415.79 383.85 Td (the ) Tj ET Q q 0 0 0 rg BT 430.42 383.85 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 450.06 383.85 Td (or ) Tj ET Q q 0 0 0 rg BT 461.37 383.85 Td (other ) Tj ET Q q 0 0 0 rg BT 484.89 383.85 Td (countries. ) Tj ET Q q 0 0 0 rg BT 527.02 383.85 Td ( ) Tj ET Q q 0 0 0 rg BT 529.44 383.85 Td (In ) Tj ET Q q 0 0 0 rg BT 540.18 383.85 Td (addition, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 371.85 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 371.85 Td (one-time ) Tj ET Q q 0 0 0 rg BT 88.20 371.85 Td (deemed ) Tj ET Q q 0 0 0 rg BT 121.24 371.85 Td (r) Tj ET Q q 0 0 0 rg BT 124.76 371.85 Td (epatriation ) Tj ET Q q 0 0 0 rg BT 171.70 371.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 186.42 371.85 Td (of ) Tj ET Q q 0 0 0 rg BT 196.70 371.85 Td (appr) Tj ET Q q 0 0 0 rg BT 215.22 371.85 Td (oximately ) Tj ET Q q 0 0 0 rg BT 256.59 371.85 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 276.59 371.85 Td (billion ) Tj ET Q q 0 0 0 rg BT 305.20 371.85 Td (will ) Tj ET Q q 0 0 0 rg BT 322.71 371.85 Td (be ) Tj ET Q q 0 0 0 rg BT 334.65 371.85 Td (payable ) Tj ET Q q 0 0 0 rg BT 368.80 371.85 Td (over ) Tj ET Q q 0 0 0 rg BT 389.07 371.85 Td (the ) Tj ET Q q 0 0 0 rg BT 403.79 371.85 Td (next ) Tj ET Q q 0 0 0 rg BT 422.94 371.85 Td (eight ) Tj ET Q q 0 0 0 rg BT 445.44 371.85 Td (years.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 347.85 Td (Third-party ) Tj ET Q q 0 0 0 rg BT 86.28 347.85 Td (royalties ) Tj ET Q q 0 0 0 rg BT 123.77 347.85 Td (represent ) Tj ET Q q 0 0 0 rg BT 164.60 347.85 Td (a ) Tj ET Q q 0 0 0 rg BT 172.10 347.85 Td (significant ) Tj ET Q q 0 0 0 rg BT 218.50 347.85 Td (percentage ) Tj ET Q q 0 0 0 rg BT 265.99 347.85 Td (of ) Tj ET Q q 0 0 0 rg BT 276.82 347.85 Td (our ) Tj ET Q q 0 0 0 rg BT 293.77 347.85 Td (pretax ) Tj ET Q q 0 0 0 rg BT 322.38 347.85 Td (income ) Tj ET Q q 0 0 0 rg BT 354.87 347.85 Td (and ) Tj ET Q q 0 0 0 rg BT 372.93 347.85 Td (operating ) Tj ET Q q 0 0 0 rg BT 414.88 347.85 Td (cash ) Tj ET Q q 0 0 0 rg BT 436.27 347.85 Td (flow) Tj ET Q q 0 0 0 rg BT 453.68 347.85 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 335.85 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 335.85 Td (e ) Tj ET Q q 0 0 0 rg BT 49.91 335.85 Td (have ) Tj ET Q q 0 0 0 rg BT 70.84 335.85 Td (enter) Tj ET Q q 0 0 0 rg BT 91.02 335.85 Td (ed ) Tj ET Q q 0 0 0 rg BT 102.52 335.85 Td (into ) Tj ET Q q 0 0 0 rg BT 120.13 335.85 Td (several ) Tj ET Q q 0 0 0 rg BT 151.07 335.85 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 208.68 335.85 Td (which ) Tj ET Q q 0 0 0 rg BT 234.62 335.85 Td (entitle ) Tj ET Q q 0 0 0 rg BT 261.67 335.85 Td (us ) Tj ET Q q 0 0 0 rg BT 272.62 335.85 Td (to ) Tj ET Q q 0 0 0 rg BT 282.46 335.85 Td (potential ) Tj ET Q q 0 0 0 rg BT 320.06 335.85 Td (r) Tj ET Q q 0 0 0 rg BT 323.59 335.85 Td (oyalties ) Tj ET Q q 0 0 0 rg BT 356.75 335.85 Td (fr) Tj ET Q q 0 0 0 rg BT 363.05 335.85 Td (om ) Tj ET Q q 0 0 0 rg BT 377.33 335.85 Td (thir) Tj ET Q q 0 0 0 rg BT 391.40 335.85 Td (d ) Tj ET Q q 0 0 0 rg BT 398.46 335.85 Td (parties ) Tj ET Q q 0 0 0 rg BT 428.30 335.85 Td (for ) Tj ET Q q 0 0 0 rg BT 442.03 335.85 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 492.96 335.85 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 540.00 335.85 Td (pr) Tj ET Q q 0 0 0 rg BT 548.52 335.85 Td (operty) Tj ET Q q 0 0 0 rg BT 573.51 335.85 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 323.85 Td (commer) Tj ET Q q 0 0 0 rg BT 67.84 323.85 Td (cialization ) Tj ET Q q 0 0 0 rg BT 112.16 323.85 Td (rights ) Tj ET Q q 0 0 0 rg BT 137.61 323.85 Td (and ) Tj ET Q q 0 0 0 rg BT 154.71 323.85 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 203.47 323.85 Td (contingent ) Tj ET Q q 0 0 0 rg BT 247.78 323.85 Td (pr) Tj ET Q q 0 0 0 rg BT 256.31 323.85 Td (oceeds ) Tj ET Q q 0 0 0 rg BT 285.61 323.85 Td (r) Tj ET Q q 0 0 0 rg BT 289.13 323.85 Td (elated ) Tj ET Q q 0 0 0 rg BT 315.67 323.85 Td (to ) Tj ET Q q 0 0 0 rg BT 325.55 323.85 Td (the ) Tj ET Q q 0 0 0 rg BT 339.87 323.85 Td (divestitur) Tj ET Q q 0 0 0 rg BT 377.27 323.85 Td (e ) Tj ET Q q 0 0 0 rg BT 383.81 323.85 Td (of ) Tj ET Q q 0 0 0 rg BT 393.69 323.85 Td (businesses. ) Tj ET Q q 0 0 0 rg BT 440.52 323.85 Td (In ) Tj ET Q q 0 0 0 rg BT 450.95 323.85 Td (many ) Tj ET Q q 0 0 0 rg BT 474.71 323.85 Td (of ) Tj ET Q q 0 0 0 rg BT 484.59 323.85 Td (these ) Tj ET Q q 0 0 0 rg BT 507.24 323.85 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 564.89 323.85 Td (we ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 311.85 Td (have ) Tj ET Q q 0 0 0 rg BT 58.20 311.85 Td (minimal, ) Tj ET Q q 0 0 0 rg BT 96.80 311.85 Td (if ) Tj ET Q q 0 0 0 rg BT 105.68 311.85 Td (any) Tj ET Q q 0 0 0 rg BT 119.57 311.85 Td (, ) Tj ET Q q 0 0 0 rg BT 125.40 311.85 Td (continuing ) Tj ET Q q 0 0 0 rg BT 171.49 311.85 Td (involvement ) Tj ET Q q 0 0 0 rg BT 223.13 311.85 Td (that ) Tj ET Q q 0 0 0 rg BT 242.01 311.85 Td (contribute ) Tj ET Q q 0 0 0 rg BT 286.44 311.85 Td (to ) Tj ET Q q 0 0 0 rg BT 297.54 311.85 Td (the ) Tj ET Q q 0 0 0 rg BT 313.08 311.85 Td (financial ) Tj ET Q q 0 0 0 rg BT 351.96 311.85 Td (success ) Tj ET Q q 0 0 0 rg BT 385.27 311.85 Td (of ) Tj ET Q q 0 0 0 rg BT 396.37 311.85 Td (those ) Tj ET Q q 0 0 0 rg BT 420.81 311.85 Td (activities. ) Tj ET Q q 0 0 0 rg BT 462.73 311.85 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 503.26 311.85 Td (have ) Tj ET Q q 0 0 0 rg BT 525.47 311.85 Td (continued ) Tj ET Q q 0 0 0 rg BT 568.22 311.85 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 299.85 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 299.85 Td (epr) Tj ET Q q 0 0 0 rg BT 52.48 299.85 Td (esent ) Tj ET Q q 0 0 0 rg BT 76.71 299.85 Td (a ) Tj ET Q q 0 0 0 rg BT 85.39 299.85 Td (significant ) Tj ET Q q 0 0 0 rg BT 131.30 299.85 Td (per) Tj ET Q q 0 0 0 rg BT 144.26 299.85 Td (centage ) Tj ET Q q 0 0 0 rg BT 179.04 299.85 Td (of ) Tj ET Q q 0 0 0 rg BT 190.50 299.85 Td (our ) Tj ET Q q 0 0 0 rg BT 208.08 299.85 Td (pr) Tj ET Q q 0 0 0 rg BT 216.60 299.85 Td (etax ) Tj ET Q q 0 0 0 rg BT 236.94 299.85 Td (income, ) Tj ET Q q 0 0 0 rg BT 272.00 299.85 Td (including ) Tj ET Q q 0 0 0 rg BT 313.45 299.85 Td (r) Tj ET Q q 0 0 0 rg BT 316.97 299.85 Td (oyalties ) Tj ET Q q 0 0 0 rg BT 351.76 299.85 Td (r) Tj ET Q q 0 0 0 rg BT 355.28 299.85 Td (elated ) Tj ET Q q 0 0 0 rg BT 383.40 299.85 Td (to ) Tj ET Q q 0 0 0 rg BT 394.86 299.85 Td (the ) Tj ET Q q 0 0 0 rg BT 410.76 299.85 Td (divestitur) Tj ET Q q 0 0 0 rg BT 448.17 299.85 Td (e ) Tj ET Q q 0 0 0 rg BT 456.29 299.85 Td (of ) Tj ET Q q 0 0 0 rg BT 467.75 299.85 Td (our ) Tj ET Q q 0 0 0 rg BT 485.33 299.85 Td (Erbitux* ) Tj ET Q q 0 0 0 rg BT 524.01 299.85 Td (and ) Tj ET Q q 0 0 0 rg BT 542.69 299.85 Td (diabetes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 287.85 Td (businesses ) Tj ET Q q 0 0 0 rg BT 80.18 287.85 Td (\(including ) Tj ET Q q 0 0 0 rg BT 123.24 287.85 Td (the ) Tj ET Q q 0 0 0 rg BT 137.41 287.85 Td (transfer ) Tj ET Q q 0 0 0 rg BT 171.03 287.85 Td (of ) Tj ET Q q 0 0 0 rg BT 180.77 287.85 Td (certain ) Tj ET Q q 0 0 0 rg BT 211.05 287.85 Td (futur) Tj ET Q q 0 0 0 rg BT 230.13 287.85 Td (e ) Tj ET Q q 0 0 0 rg BT 236.52 287.85 Td (r) Tj ET Q q 0 0 0 rg BT 240.04 287.85 Td (oyalty ) Tj ET Q q 0 0 0 rg BT 266.43 287.85 Td (rights ) Tj ET Q q 0 0 0 rg BT 291.73 287.85 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 335.35 287.85 Td (to ) Tj ET Q q 0 0 0 rg BT 344.94 287.85 Td (Amylin, ) Tj ET Q q 0 0 0 rg BT 377.72 287.85 Td (Onglyza* ) Tj ET Q q 0 0 0 rg BT 418.00 287.85 Td (and ) Tj ET Q q 0 0 0 rg BT 434.96 287.85 Td (Farxiga* ) Tj ET Q q 0 0 0 rg BT 474.13 287.85 Td (pr) Tj ET Q q 0 0 0 rg BT 482.65 287.85 Td (oduct ) Tj ET Q q 0 0 0 rg BT 506.83 287.85 Td (sales\), ) Tj ET Q q 0 0 0 rg BT 534.61 287.85 Td (our ) Tj ET Q q 0 0 0 rg BT 550.46 287.85 Td (Sanofi ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 275.85 Td (alliance,) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 70.71 275.85 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 73.28 275.85 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 124.73 275.85 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 172.28 275.85 Td (pr) Tj ET Q q 0 0 0 rg BT 180.80 275.85 Td (operty ) Tj ET Q q 0 0 0 rg BT 208.92 275.85 Td (and ) Tj ET Q q 0 0 0 rg BT 226.49 275.85 Td (the ) Tj ET Q q 0 0 0 rg BT 241.28 275.85 Td (Mer) Tj ET Q q 0 0 0 rg BT 257.57 275.85 Td (ck ) Tj ET Q q 0 0 0 rg BT 269.02 275.85 Td (patent ) Tj ET Q q 0 0 0 rg BT 296.58 275.85 Td (infringement ) Tj ET Q q 0 0 0 rg BT 350.26 275.85 Td (settlement. Pr) Tj ET Q q 0 0 0 rg BT 405.43 275.85 Td (etax ) Tj ET Q q 0 0 0 rg BT 424.65 275.85 Td (income ) Tj ET Q q 0 0 0 rg BT 456.10 275.85 Td (generated ) Tj ET Q q 0 0 0 rg BT 498.66 275.85 Td (fr) Tj ET Q q 0 0 0 rg BT 504.96 275.85 Td (om ) Tj ET Q q 0 0 0 rg BT 519.75 275.85 Td (r) Tj ET Q q 0 0 0 rg BT 523.27 275.85 Td (oyalties ) Tj ET Q q 0 0 0 rg BT 556.94 275.85 Td (wer) Tj ET Q q 0 0 0 rg BT 571.57 275.85 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 263.85 Td (appr) Tj ET Q q 0 0 0 rg BT 54.52 263.85 Td (oximately ) Tj ET Q q 0 0 0 rg BT 96.54 263.85 Td ($1.2 ) Tj ET Q q 0 0 0 rg BT 117.19 263.85 Td (billion ) Tj ET Q q 0 0 0 rg BT 146.46 263.85 Td (in ) Tj ET Q q 0 0 0 rg BT 157.39 263.85 Td (2017 ) Tj ET Q q 0 0 0 rg BT 180.54 263.85 Td (and ) Tj ET Q q 0 0 0 rg BT 198.69 263.85 Td (is ) Tj ET Q q 0 0 0 rg BT 208.51 263.85 Td (expected ) Tj ET Q q 0 0 0 rg BT 246.63 263.85 Td (to ) Tj ET Q q 0 0 0 rg BT 257.56 263.85 Td (incr) Tj ET Q q 0 0 0 rg BT 273.30 263.85 Td (ease ) Tj ET Q q 0 0 0 rg BT 294.22 263.85 Td (in ) Tj ET Q q 0 0 0 rg BT 305.15 263.85 Td (2018. Our ) Tj ET Q q 0 0 0 rg BT 349.41 263.85 Td (pr) Tj ET Q q 0 0 0 rg BT 357.93 263.85 Td (etax ) Tj ET Q q 0 0 0 rg BT 377.74 263.85 Td (income ) Tj ET Q q 0 0 0 rg BT 409.77 263.85 Td (could ) Tj ET Q q 0 0 0 rg BT 435.13 263.85 Td (be ) Tj ET Q q 0 0 0 rg BT 447.72 263.85 Td (adversely ) Tj ET Q q 0 0 0 rg BT 489.19 263.85 Td (affected ) Tj ET Q q 0 0 0 rg BT 523.99 263.85 Td (if ) Tj ET Q q 0 0 0 rg BT 532.70 263.85 Td (the ) Tj ET Q q 0 0 0 rg BT 548.07 263.85 Td (r) Tj ET Q q 0 0 0 rg BT 551.59 263.85 Td (oyalty ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 251.85 Td (str) Tj ET Q q 0 0 0 rg BT 46.19 251.85 Td (eams ) Tj ET Q q 0 0 0 rg BT 69.24 251.85 Td (decline ) Tj ET Q q 0 0 0 rg BT 100.61 251.85 Td (in ) Tj ET Q q 0 0 0 rg BT 110.89 251.85 Td (futur) Tj ET Q q 0 0 0 rg BT 129.97 251.85 Td (e ) Tj ET Q q 0 0 0 rg BT 136.91 251.85 Td (periods.) Tj ET Q endstream endobj 45 0 obj <> endobj 46 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (22) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.61 749.25 Td (failure ) Tj ET Q q 0 0 0 rg BT 84.89 749.25 Td (of ) Tj ET Q q 0 0 0 rg BT 95.72 749.25 Td (third ) Tj ET Q q 0 0 0 rg BT 118.23 749.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 148.50 749.25 Td (to ) Tj ET Q q 0 0 0 rg BT 158.78 749.25 Td (meet ) Tj ET Q q 0 0 0 rg BT 180.72 749.25 Td (their ) Tj ET Q q 0 0 0 rg BT 202.67 749.25 Td (contractual, ) Tj ET Q q 0 0 0 rg BT 254.89 749.25 Td (regulatory) Tj ET Q q 0 0 0 rg BT 297.30 749.25 Td (, ) Tj ET Q q 0 0 0 rg BT 302.30 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 320.36 749.25 Td (other ) Tj ET Q q 0 0 0 rg BT 344.53 749.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 392.60 749.25 Td (could ) Tj ET Q q 0 0 0 rg BT 417.88 749.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 458.69 749.25 Td (af) Tj ET Q q 0 0 0 rg BT 466.84 749.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 484.33 749.25 Td (our ) Tj ET Q q 0 0 0 rg BT 501.28 749.25 Td (business.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 737.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.97 737.25 Td (r) Tj ET Q q 0 0 0 rg BT 55.50 737.25 Td (ely ) Tj ET Q q 0 0 0 rg BT 71.27 737.25 Td (on ) Tj ET Q q 0 0 0 rg BT 85.40 737.25 Td (suppliers, ) Tj ET Q q 0 0 0 rg BT 128.69 737.25 Td (vendors, ) Tj ET Q q 0 0 0 rg BT 166.98 737.25 Td (outsour) Tj ET Q q 0 0 0 rg BT 197.17 737.25 Td (cing ) Tj ET Q q 0 0 0 rg BT 218.51 737.25 Td (partners, ) Tj ET Q q 0 0 0 rg BT 259.02 737.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 295.36 737.25 Td (partners ) Tj ET Q q 0 0 0 rg BT 333.38 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 352.50 737.25 Td (other ) Tj ET Q q 0 0 0 rg BT 377.73 737.25 Td (thir) Tj ET Q q 0 0 0 rg BT 391.81 737.25 Td (d ) Tj ET Q q 0 0 0 rg BT 400.93 737.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 432.83 737.25 Td (to ) Tj ET Q q 0 0 0 rg BT 444.74 737.25 Td (r) Tj ET Q q 0 0 0 rg BT 448.26 737.25 Td (esear) Tj ET Q q 0 0 0 rg BT 469.55 737.25 Td (ch, ) Tj ET Q q 0 0 0 rg BT 485.61 737.25 Td (develop, ) Tj ET Q q 0 0 0 rg BT 523.33 737.25 Td (manufactur) Tj ET Q q 0 0 0 rg BT 569.06 737.25 Td (e, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (commer) Tj ET Q q 0 0 0 rg BT 67.84 725.25 Td (cialize, ) Tj ET Q q 0 0 0 rg BT 99.39 725.25 Td (co-pr) Tj ET Q q 0 0 0 rg BT 120.68 725.25 Td (omote ) Tj ET Q q 0 0 0 rg BT 148.06 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 166.00 725.25 Td (sell ) Tj ET Q q 0 0 0 rg BT 182.84 725.25 Td (our ) Tj ET Q q 0 0 0 rg BT 199.67 725.25 Td (pr) Tj ET Q q 0 0 0 rg BT 208.19 725.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 239.75 725.25 Td (manage ) Tj ET Q q 0 0 0 rg BT 274.35 725.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 305.62 725.25 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 351.61 725.25 Td (selling, ) Tj ET Q q 0 0 0 rg BT 383.72 725.25 Td (human ) Tj ET Q q 0 0 0 rg BT 413.89 725.25 Td (r) Tj ET Q q 0 0 0 rg BT 417.41 725.25 Td (esour) Tj ET Q q 0 0 0 rg BT 439.26 725.25 Td (ce, ) Tj ET Q q 0 0 0 rg BT 453.58 725.25 Td (finance, ) Tj ET Q q 0 0 0 rg BT 488.46 725.25 Td (IT) Tj ET Q q 0 0 0 rg BT 497.17 725.25 Td ( ) Tj ET Q q 0 0 0 rg BT 500.11 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 518.06 725.25 Td (other ) Tj ET Q q 0 0 0 rg BT 542.11 725.25 Td (business ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (unit ) Tj ET Q q 0 0 0 rg BT 54.22 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 71.87 713.25 Td (functional ) Tj ET Q q 0 0 0 rg BT 115.08 713.25 Td (services, ) Tj ET Q q 0 0 0 rg BT 152.45 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.11 713.25 Td (meet ) Tj ET Q q 0 0 0 rg BT 191.64 713.25 Td (their ) Tj ET Q q 0 0 0 rg BT 213.19 713.25 Td (contractual, ) Tj ET Q q 0 0 0 rg BT 264.45 713.25 Td (r) Tj ET Q q 0 0 0 rg BT 267.97 713.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 308.96 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 326.62 713.25 Td (other ) Tj ET Q q 0 0 0 rg BT 350.38 713.25 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 400.55 713.25 Td (Using ) Tj ET Q q 0 0 0 rg BT 427.10 713.25 Td (these ) Tj ET Q q 0 0 0 rg BT 450.30 713.25 Td (thir) Tj ET Q q 0 0 0 rg BT 464.38 713.25 Td (d ) Tj ET Q q 0 0 0 rg BT 472.04 713.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 502.47 713.25 Td (poses ) Tj ET Q q 0 0 0 rg BT 527.35 713.25 Td (a ) Tj ET Q q 0 0 0 rg BT 535.01 713.25 Td (number ) Tj ET Q q 0 0 0 rg BT 568.22 713.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (risks, ) Tj ET Q q 0 0 0 rg BT 59.76 701.25 Td (such ) Tj ET Q q 0 0 0 rg BT 80.47 701.25 Td (as: ) Tj ET Q q 0 0 0 rg BT 95.06 701.25 Td (\(i\) ) Tj ET Q q 0 0 0 rg BT 106.87 701.25 Td (they ) Tj ET Q q 0 0 0 rg BT 125.90 701.25 Td (may ) Tj ET Q q 0 0 0 rg BT 144.93 701.25 Td (not ) Tj ET Q q 0 0 0 rg BT 160.08 701.25 Td (perform ) Tj ET Q q 0 0 0 rg BT 194.67 701.25 Td (to ) Tj ET Q q 0 0 0 rg BT 204.82 701.25 Td (our ) Tj ET Q q 0 0 0 rg BT 221.09 701.25 Td (standar) Tj ET Q q 0 0 0 rg BT 251.28 701.25 Td (ds ) Tj ET Q q 0 0 0 rg BT 262.54 701.25 Td (or ) Tj ET Q q 0 0 0 rg BT 273.81 701.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 296.17 701.25 Td (r) Tj ET Q q 0 0 0 rg BT 299.69 701.25 Td (equir) Tj ET Q q 0 0 0 rg BT 320.43 701.25 Td (ements, ) Tj ET Q q 0 0 0 rg BT 353.07 701.25 Td (for ) Tj ET Q q 0 0 0 rg BT 367.11 701.25 Td (example, ) Tj ET Q q 0 0 0 rg BT 405.30 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 415.45 701.25 Td (r) Tj ET Q q 0 0 0 rg BT 418.97 701.25 Td (elation ) Tj ET Q q 0 0 0 rg BT 449.12 701.25 Td (to ) Tj ET Q q 0 0 0 rg BT 459.27 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 473.86 701.25 Td (outsour) Tj ET Q q 0 0 0 rg BT 504.05 701.25 Td (cing ) Tj ET Q q 0 0 0 rg BT 523.64 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 533.79 701.25 Td (significant ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 69.41 689.25 Td (development ) Tj ET Q q 0 0 0 rg BT 123.37 689.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 162.89 689.25 Td (for ) Tj ET Q q 0 0 0 rg BT 177.98 689.25 Td (innovative ) Tj ET Q q 0 0 0 rg BT 223.06 689.25 Td (medicines ) Tj ET Q q 0 0 0 rg BT 266.46 689.25 Td (to ) Tj ET Q q 0 0 0 rg BT 277.67 689.25 Td (some ) Tj ET Q q 0 0 0 rg BT 301.64 689.25 Td (contract ) Tj ET Q q 0 0 0 rg BT 338.39 689.25 Td (r) Tj ET Q q 0 0 0 rg BT 341.91 689.25 Td (esear) Tj ET Q q 0 0 0 rg BT 363.20 689.25 Td (ch ) Tj ET Q q 0 0 0 rg BT 376.06 689.25 Td (or) Tj ET Q q 0 0 0 rg BT 384.58 689.25 Td (ganizations; ) Tj ET Q q 0 0 0 rg BT 437.45 689.25 Td (\(ii\) ) Tj ET Q q 0 0 0 rg BT 453.09 689.25 Td (they ) Tj ET Q q 0 0 0 rg BT 473.17 689.25 Td (may ) Tj ET Q q 0 0 0 rg BT 493.25 689.25 Td (not ) Tj ET Q q 0 0 0 rg BT 509.45 689.25 Td (pr) Tj ET Q q 0 0 0 rg BT 517.97 689.25 Td (oduce ) Tj ET Q q 0 0 0 rg BT 545.27 689.25 Td (r) Tj ET Q q 0 0 0 rg BT 548.79 689.25 Td (eliable ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 677.25 Td (esults; ) Tj ET Q q 0 0 0 rg BT 67.87 677.25 Td (\(iii\) ) Tj ET Q q 0 0 0 rg BT 85.10 677.25 Td (they ) Tj ET Q q 0 0 0 rg BT 103.99 677.25 Td (may ) Tj ET Q q 0 0 0 rg BT 122.88 677.25 Td (not ) Tj ET Q q 0 0 0 rg BT 137.90 677.25 Td (perform ) Tj ET Q q 0 0 0 rg BT 172.36 677.25 Td (in ) Tj ET Q q 0 0 0 rg BT 182.37 677.25 Td (a ) Tj ET Q q 0 0 0 rg BT 189.61 677.25 Td (timely ) Tj ET Q q 0 0 0 rg BT 216.28 677.25 Td (manner; ) Tj ET Q q 0 0 0 rg BT 252.40 677.25 Td (\(iv\) ) Tj ET Q q 0 0 0 rg BT 268.51 677.25 Td (they ) Tj ET Q q 0 0 0 rg BT 287.40 677.25 Td (may ) Tj ET Q q 0 0 0 rg BT 306.30 677.25 Td (not ) Tj ET Q q 0 0 0 rg BT 321.31 677.25 Td (maintain ) Tj ET Q q 0 0 0 rg BT 359.11 677.25 Td (confidentiality ) Tj ET Q q 0 0 0 rg BT 419.11 677.25 Td (of ) Tj ET Q q 0 0 0 rg BT 429.12 677.25 Td (our ) Tj ET Q q 0 0 0 rg BT 445.25 677.25 Td (pr) Tj ET Q q 0 0 0 rg BT 453.77 677.25 Td (oprietary ) Tj ET Q q 0 0 0 rg BT 493.22 677.25 Td (information; ) Tj ET Q q 0 0 0 rg BT 546.01 677.25 Td (\(v\) ) Tj ET Q q 0 0 0 rg BT 559.35 677.25 Td (they ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (may ) Tj ET Q q 0 0 0 rg BT 55.81 665.25 Td (incur ) Tj ET Q q 0 0 0 rg BT 80.07 665.25 Td (a ) Tj ET Q q 0 0 0 rg BT 88.22 665.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 133.60 665.25 Td (cyberattack ) Tj ET Q q 0 0 0 rg BT 183.39 665.25 Td (or ) Tj ET Q q 0 0 0 rg BT 195.43 665.25 Td (business ) Tj ET Q q 0 0 0 rg BT 232.48 665.25 Td (disruption; ) Tj ET Q q 0 0 0 rg BT 280.08 665.25 Td (\(vi\) ) Tj ET Q q 0 0 0 rg BT 297.11 665.25 Td (disputes ) Tj ET Q q 0 0 0 rg BT 333.04 665.25 Td (may ) Tj ET Q q 0 0 0 rg BT 352.85 665.25 Td (arise ) Tj ET Q q 0 0 0 rg BT 376.00 665.25 Td (with ) Tj ET Q q 0 0 0 rg BT 396.38 665.25 Td (r) Tj ET Q q 0 0 0 rg BT 399.90 665.25 Td (espect ) Tj ET Q q 0 0 0 rg BT 428.04 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 438.97 665.25 Td (ownership ) Tj ET Q q 0 0 0 rg BT 483.79 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 494.72 665.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 521.21 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 532.14 665.25 Td (technology ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (developed ) Tj ET Q q 0 0 0 rg BT 81.65 653.25 Td (with ) Tj ET Q q 0 0 0 rg BT 104.00 653.25 Td (our ) Tj ET Q q 0 0 0 rg BT 123.01 653.25 Td (partners; ) Tj ET Q q 0 0 0 rg BT 165.35 653.25 Td (and ) Tj ET Q q 0 0 0 rg BT 185.47 653.25 Td (\(vii\) ) Tj ET Q q 0 0 0 rg BT 207.25 653.25 Td (disagr) Tj ET Q q 0 0 0 rg BT 232.44 653.25 Td (eements ) Tj ET Q q 0 0 0 rg BT 269.77 653.25 Td (could ) Tj ET Q q 0 0 0 rg BT 297.10 653.25 Td (cause ) Tj ET Q q 0 0 0 rg BT 324.99 653.25 Td (delays ) Tj ET Q q 0 0 0 rg BT 355.66 653.25 Td (in, ) Tj ET Q q 0 0 0 rg BT 371.06 653.25 Td (or ) Tj ET Q q 0 0 0 rg BT 385.07 653.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 436.85 653.25 Td (of, ) Tj ET Q q 0 0 0 rg BT 452.25 653.25 Td (the ) Tj ET Q q 0 0 0 rg BT 469.59 653.25 Td (r) Tj ET Q q 0 0 0 rg BT 473.11 653.25 Td (esear) Tj ET Q q 0 0 0 rg BT 494.40 653.25 Td (ch, ) Tj ET Q q 0 0 0 rg BT 511.46 653.25 Td (development ) Tj ET Q q 0 0 0 rg BT 567.11 653.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (commer) Tj ET Q q 0 0 0 rg BT 67.84 641.25 Td (cialization ) Tj ET Q q 0 0 0 rg BT 113.14 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 123.99 641.25 Td (the ) Tj ET Q q 0 0 0 rg BT 139.28 641.25 Td (pr) Tj ET Q q 0 0 0 rg BT 147.80 641.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 173.09 641.25 Td (or ) Tj ET Q q 0 0 0 rg BT 185.05 641.25 Td (r) Tj ET Q q 0 0 0 rg BT 188.57 641.25 Td (esult ) Tj ET Q q 0 0 0 rg BT 210.53 641.25 Td (in ) Tj ET Q q 0 0 0 rg BT 221.38 641.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 261.12 641.25 Td (or ) Tj ET Q q 0 0 0 rg BT 273.09 641.25 Td (arbitration. ) Tj ET Q q 0 0 0 rg BT 322.56 641.25 Td (Mor) Tj ET Q q 0 0 0 rg BT 339.41 641.25 Td (eover) Tj ET Q q 0 0 0 rg BT 360.51 641.25 Td (, ) Tj ET Q q 0 0 0 rg BT 366.08 641.25 Td (some ) Tj ET Q q 0 0 0 rg BT 389.70 641.25 Td (thir) Tj ET Q q 0 0 0 rg BT 403.78 641.25 Td (d ) Tj ET Q q 0 0 0 rg BT 411.85 641.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 442.71 641.25 Td (ar) Tj ET Q q 0 0 0 rg BT 451.23 641.25 Td (e ) Tj ET Q q 0 0 0 rg BT 458.74 641.25 Td (located ) Tj ET Q q 0 0 0 rg BT 491.24 641.25 Td (in ) Tj ET Q q 0 0 0 rg BT 502.09 641.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 536.83 641.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 568.23 641.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (political ) Tj ET Q q 0 0 0 rg BT 72.73 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 91.12 629.25 Td (social ) Tj ET Q q 0 0 0 rg BT 118.40 629.25 Td (risk, ) Tj ET Q q 0 0 0 rg BT 139.30 629.25 Td (corruption, ) Tj ET Q q 0 0 0 rg BT 187.97 629.25 Td (infrastructur) Tj ET Q q 0 0 0 rg BT 238.72 629.25 Td (e ) Tj ET Q q 0 0 0 rg BT 246.55 629.25 Td (pr) Tj ET Q q 0 0 0 rg BT 255.07 629.25 Td (oblems ) Tj ET Q q 0 0 0 rg BT 286.80 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 305.19 629.25 Td (natural ) Tj ET Q q 0 0 0 rg BT 338.03 629.25 Td (disasters, ) Tj ET Q q 0 0 0 rg BT 379.49 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 390.66 629.25 Td (addition ) Tj ET Q q 0 0 0 rg BT 427.39 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 438.57 629.25 Td (country ) Tj ET Q q 0 0 0 rg BT 472.51 629.25 Td (specific ) Tj ET Q q 0 0 0 rg BT 506.45 629.25 Td (privacy ) Tj ET Q q 0 0 0 rg BT 539.83 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 558.22 629.25 Td (data ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (security ) Tj ET Q q 0 0 0 rg BT 69.86 617.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 87.07 617.25 Td (given ) Tj ET Q q 0 0 0 rg BT 110.93 617.25 Td (curr) Tj ET Q q 0 0 0 rg BT 127.78 617.25 Td (ent ) Tj ET Q q 0 0 0 rg BT 142.21 617.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 164.41 617.25 Td (and ) Tj ET Q q 0 0 0 rg BT 181.62 617.25 Td (r) Tj ET Q q 0 0 0 rg BT 185.14 617.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 225.67 617.25 Td (envir) Tj ET Q q 0 0 0 rg BT 245.84 617.25 Td (onments. ) Tj ET Q q 0 0 0 rg BT 283.88 617.25 Td (The ) Tj ET Q q 0 0 0 rg BT 301.09 617.25 Td (failur) Tj ET Q q 0 0 0 rg BT 322.94 617.25 Td (e ) Tj ET Q q 0 0 0 rg BT 329.59 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 339.57 617.25 Td (any ) Tj ET Q q 0 0 0 rg BT 356.22 617.25 Td (critical ) Tj ET Q q 0 0 0 rg BT 387.31 617.25 Td (thir) Tj ET Q q 0 0 0 rg BT 401.39 617.25 Td (d ) Tj ET Q q 0 0 0 rg BT 408.59 617.25 Td (party ) Tj ET Q q 0 0 0 rg BT 431.91 617.25 Td (to ) Tj ET Q q 0 0 0 rg BT 441.89 617.25 Td (meet ) Tj ET Q q 0 0 0 rg BT 462.98 617.25 Td (its ) Tj ET Q q 0 0 0 rg BT 474.63 617.25 Td (obligations, ) Tj ET Q q 0 0 0 rg BT 524.34 617.25 Td (including ) Tj ET Q q 0 0 0 rg BT 564.33 617.25 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (futur) Tj ET Q q 0 0 0 rg BT 55.08 605.25 Td (e ) Tj ET Q q 0 0 0 rg BT 61.84 605.25 Td (r) Tj ET Q q 0 0 0 rg BT 65.36 605.25 Td (oyalty ) Tj ET Q q 0 0 0 rg BT 92.11 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 109.43 605.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 150.08 605.25 Td (payments; ) Tj ET Q q 0 0 0 rg BT 193.50 605.25 Td (adequately ) Tj ET Q q 0 0 0 rg BT 239.69 605.25 Td (deploy ) Tj ET Q q 0 0 0 rg BT 268.67 605.25 Td (business ) Tj ET Q q 0 0 0 rg BT 304.88 605.25 Td (continuity ) Tj ET Q q 0 0 0 rg BT 347.19 605.25 Td (plans ) Tj ET Q q 0 0 0 rg BT 371.18 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 381.28 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 395.82 605.25 Td (event ) Tj ET Q q 0 0 0 rg BT 419.23 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 429.33 605.25 Td (a ) Tj ET Q q 0 0 0 rg BT 436.65 605.25 Td (crisis; ) Tj ET Q q 0 0 0 rg BT 463.97 605.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 492.96 605.25 Td (satisfactorily ) Tj ET Q q 0 0 0 rg BT 547.51 605.25 Td (r) Tj ET Q q 0 0 0 rg BT 551.03 605.25 Td (esolve ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 81.70 593.25 Td (disagr) Tj ET Q q 0 0 0 rg BT 106.89 593.25 Td (eements ) Tj ET Q q 0 0 0 rg BT 142.58 593.25 Td (with ) Tj ET Q q 0 0 0 rg BT 163.29 593.25 Td (us ) Tj ET Q q 0 0 0 rg BT 175.66 593.25 Td (or ) Tj ET Q q 0 0 0 rg BT 188.04 593.25 Td (addr) Tj ET Q q 0 0 0 rg BT 206.56 593.25 Td (ess ) Tj ET Q q 0 0 0 rg BT 222.26 593.25 Td (other ) Tj ET Q q 0 0 0 rg BT 246.85 593.25 Td (factors, ) Tj ET Q q 0 0 0 rg BT 280.61 593.25 Td (could ) Tj ET Q q 0 0 0 rg BT 306.31 593.25 Td (have ) Tj ET Q q 0 0 0 rg BT 328.67 593.25 Td (a ) Tj ET Q q 0 0 0 rg BT 337.15 593.25 Td (material ) Tj ET Q q 0 0 0 rg BT 374.52 593.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 409.10 593.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 439.79 593.25 Td (on ) Tj ET Q q 0 0 0 rg BT 453.28 593.25 Td (our ) Tj ET Q q 0 0 0 rg BT 470.65 593.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 516.91 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 535.39 593.25 Td (r) Tj ET Q q 0 0 0 rg BT 538.91 593.25 Td (esults. ) Tj ET Q q 0 0 0 rg BT 567.67 593.25 Td (In ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 74.10 581.25 Td (if ) Tj ET Q q 0 0 0 rg BT 81.93 581.25 Td (these ) Tj ET Q q 0 0 0 rg BT 104.74 581.25 Td (thir) Tj ET Q q 0 0 0 rg BT 118.82 581.25 Td (d ) Tj ET Q q 0 0 0 rg BT 126.09 581.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 156.13 581.25 Td (violate, ) Tj ET Q q 0 0 0 rg BT 188.11 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 199.27 581.25 Td (ar) Tj ET Q q 0 0 0 rg BT 207.79 581.25 Td (e ) Tj ET Q q 0 0 0 rg BT 214.50 581.25 Td (alleged ) Tj ET Q q 0 0 0 rg BT 246.20 581.25 Td (to ) Tj ET Q q 0 0 0 rg BT 256.25 581.25 Td (have ) Tj ET Q q 0 0 0 rg BT 277.39 581.25 Td (violated, ) Tj ET Q q 0 0 0 rg BT 314.37 581.25 Td (any ) Tj ET Q q 0 0 0 rg BT 331.08 581.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 351.69 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 362.85 581.25 Td (r) Tj ET Q q 0 0 0 rg BT 366.37 581.25 Td (egulations, ) Tj ET Q q 0 0 0 rg BT 412.80 581.25 Td (including ) Tj ET Q q 0 0 0 rg BT 452.84 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 467.33 581.25 Td (local ) Tj ET Q q 0 0 0 rg BT 489.59 581.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 554.62 581.25 Td (code, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 55.56 569.25 Td (For) Tj ET Q q 0 0 0 rg BT 70.19 569.25 Td (eign ) Tj ET Q q 0 0 0 rg BT 89.75 569.25 Td (Corrupt ) Tj ET Q q 0 0 0 rg BT 124.32 569.25 Td (Practice ) Tj ET Q q 0 0 0 rg BT 160.36 569.25 Td (Act, ) Tj ET Q q 0 0 0 rg BT 178.53 569.25 Td (UK ) Tj ET Q q 0 0 0 rg BT 194.76 569.25 Td (Bribery ) Tj ET Q q 0 0 0 rg BT 227.48 569.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 243.14 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 260.48 569.25 Td (other ) Tj ET Q q 0 0 0 rg BT 283.93 569.25 Td (similar ) Tj ET Q q 0 0 0 rg BT 314.61 569.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 335.29 569.25 Td (and ) Tj ET Q q 0 0 0 rg BT 352.63 569.25 Td (r) Tj ET Q q 0 0 0 rg BT 356.15 569.25 Td (egulations, ) Tj ET Q q 0 0 0 rg BT 402.66 569.25 Td (during ) Tj ET Q q 0 0 0 rg BT 431.67 569.25 Td (the ) Tj ET Q q 0 0 0 rg BT 446.23 569.25 Td (performance ) Tj ET Q q 0 0 0 rg BT 499.67 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 509.78 569.25 Td (their ) Tj ET Q q 0 0 0 rg BT 531.01 569.25 Td (obligations ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (for ) Tj ET Q q 0 0 0 rg BT 49.04 557.25 Td (us, ) Tj ET Q q 0 0 0 rg BT 61.80 557.25 Td (it ) Tj ET Q q 0 0 0 rg BT 68.72 557.25 Td (is ) Tj ET Q q 0 0 0 rg BT 76.76 557.25 Td (possible ) Tj ET Q q 0 0 0 rg BT 110.91 557.25 Td (that ) Tj ET Q q 0 0 0 rg BT 127.83 557.25 Td (we ) Tj ET Q q 0 0 0 rg BT 140.31 557.25 Td (could ) Tj ET Q q 0 0 0 rg BT 163.90 557.25 Td (suffer ) Tj ET Q q 0 0 0 rg BT 188.04 557.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 224.96 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 241.33 557.25 Td (r) Tj ET Q q 0 0 0 rg BT 244.85 557.25 Td (eputational ) Tj ET Q q 0 0 0 rg BT 291.77 557.25 Td (harm ) Tj ET Q q 0 0 0 rg BT 314.26 557.25 Td (or ) Tj ET Q q 0 0 0 rg BT 324.52 557.25 Td (other ) Tj ET Q q 0 0 0 rg BT 346.99 557.25 Td (negative ) Tj ET Q q 0 0 0 rg BT 382.23 557.25 Td (outcomes, ) Tj ET Q q 0 0 0 rg BT 423.87 557.25 Td (including ) Tj ET Q q 0 0 0 rg BT 463.01 557.25 Td (possible ) Tj ET Q q 0 0 0 rg BT 497.16 557.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 518.52 557.25 Td (consequences.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (Failure ) Tj ET Q q 0 0 0 rg BT 69.62 533.25 Td (to ) Tj ET Q q 0 0 0 rg BT 79.90 533.25 Td (execute ) Tj ET Q q 0 0 0 rg BT 113.49 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 130.44 533.25 Td (business ) Tj ET Q q 0 0 0 rg BT 167.96 533.25 Td (strategy ) Tj ET Q q 0 0 0 rg BT 202.67 533.25 Td (could ) Tj ET Q q 0 0 0 rg BT 227.95 533.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 268.77 533.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 299.04 533.25 Td (our ) Tj ET Q q 0 0 0 rg BT 316.00 533.25 Td (growth ) Tj ET Q q 0 0 0 rg BT 347.40 533.25 Td (and ) Tj ET Q q 0 0 0 rg BT 365.46 533.25 Td (profitability) Tj ET Q q 0 0 0 rg BT 413.42 533.25 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.36 521.25 Td (strategy ) Tj ET Q q 0 0 0 rg BT 88.83 521.25 Td (is ) Tj ET Q q 0 0 0 rg BT 97.74 521.25 Td (focused ) Tj ET Q q 0 0 0 rg BT 130.54 521.25 Td (on ) Tj ET Q q 0 0 0 rg BT 142.78 521.25 Td (delivering ) Tj ET Q q 0 0 0 rg BT 185.57 521.25 Td (innovative, ) Tj ET Q q 0 0 0 rg BT 231.97 521.25 Td (transformational ) Tj ET Q q 0 0 0 rg BT 302.01 521.25 Td (medicines ) Tj ET Q q 0 0 0 rg BT 344.24 521.25 Td (to ) Tj ET Q q 0 0 0 rg BT 354.27 521.25 Td (patients. ) Tj ET Q q 0 0 0 rg BT 390.68 521.25 Td (If ) Tj ET Q q 0 0 0 rg BT 399.04 521.25 Td (we ) Tj ET Q q 0 0 0 rg BT 412.39 521.25 Td (ar) Tj ET Q q 0 0 0 rg BT 420.91 521.25 Td (e ) Tj ET Q q 0 0 0 rg BT 427.60 521.25 Td (unable ) Tj ET Q q 0 0 0 rg BT 457.06 521.25 Td (to ) Tj ET Q q 0 0 0 rg BT 467.09 521.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 517.10 521.25 Td (execute ) Tj ET Q q 0 0 0 rg BT 549.32 521.25 Td (on ) Tj ET Q q 0 0 0 rg BT 561.56 521.25 Td (this ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (strategy) Tj ET Q q 0 0 0 rg BT 67.67 509.25 Td (, ) Tj ET Q q 0 0 0 rg BT 72.49 509.25 Td (this ) Tj ET Q q 0 0 0 rg BT 89.27 509.25 Td (could ) Tj ET Q q 0 0 0 rg BT 113.81 509.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 157.23 509.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 186.78 509.25 Td (our ) Tj ET Q q 0 0 0 rg BT 203.00 509.25 Td (futur) Tj ET Q q 0 0 0 rg BT 222.07 509.25 Td (e ) Tj ET Q q 0 0 0 rg BT 228.84 509.25 Td (r) Tj ET Q q 0 0 0 rg BT 232.36 509.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 257.47 509.25 Td (of ) Tj ET Q q 0 0 0 rg BT 267.57 509.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 312.68 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 330.01 509.25 Td (market ) Tj ET Q q 0 0 0 rg BT 360.10 509.25 Td (capitalization. ) Tj ET Q q 0 0 0 rg BT 419.93 509.25 Td (In ) Tj ET Q q 0 0 0 rg BT 430.59 509.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 476.79 509.25 Td (with ) Tj ET Q q 0 0 0 rg BT 496.35 509.25 Td (this ) Tj ET Q q 0 0 0 rg BT 513.12 509.25 Td (strategy) Tj ET Q q 0 0 0 rg BT 544.79 509.25 Td (, ) Tj ET Q q 0 0 0 rg BT 549.62 509.25 Td (we ) Tj ET Q q 0 0 0 rg BT 563.05 509.25 Td (ar) Tj ET Q q 0 0 0 rg BT 571.57 509.25 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 47.02 497.25 Td (the ) Tj ET Q q 0 0 0 rg BT 62.48 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 71.00 497.25 Td (ocess ) Tj ET Q q 0 0 0 rg BT 95.91 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 106.93 497.25 Td (evolving ) Tj ET Q q 0 0 0 rg BT 144.05 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 161.19 497.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 203.32 497.25 Td (model ) Tj ET Q q 0 0 0 rg BT 231.00 497.25 Td (to ) Tj ET Q q 0 0 0 rg BT 242.02 497.25 Td (focus ) Tj ET Q q 0 0 0 rg BT 266.38 497.25 Td (on ) Tj ET Q q 0 0 0 rg BT 279.62 497.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 325.63 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 336.65 497.25 Td (commer) Tj ET Q q 0 0 0 rg BT 368.49 497.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 386.73 497.25 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 443.31 497.25 Td (against ) Tj ET Q q 0 0 0 rg BT 476.00 497.25 Td (key ) Tj ET Q q 0 0 0 rg BT 492.56 497.25 Td (brands ) Tj ET Q q 0 0 0 rg BT 523.59 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 541.84 497.25 Td (markets, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (accelerate ) Tj ET Q q 0 0 0 rg BT 80.15 485.25 Td (the ) Tj ET Q q 0 0 0 rg BT 94.87 485.25 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 132.09 485.25 Td (str) Tj ET Q q 0 0 0 rg BT 142.28 485.25 Td (eamline ) Tj ET Q q 0 0 0 rg BT 176.44 485.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 221.73 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 239.23 485.25 Td (r) Tj ET Q q 0 0 0 rg BT 242.75 485.25 Td (ealign ) Tj ET Q q 0 0 0 rg BT 270.25 485.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 331.65 485.25 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 380.81 485.25 Td (that ) Tj ET Q q 0 0 0 rg BT 398.88 485.25 Td (br) Tj ET Q q 0 0 0 rg BT 407.40 485.25 Td (oaden ) Tj ET Q q 0 0 0 rg BT 434.34 485.25 Td (biologics ) Tj ET Q q 0 0 0 rg BT 473.51 485.25 Td (capabilities, ) Tj ET Q q 0 0 0 rg BT 525.18 485.25 Td (among ) Tj ET Q q 0 0 0 rg BT 554.91 485.25 Td (other ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (things. ) Tj ET Q q 0 0 0 rg BT 65.34 473.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 83.84 473.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 111.78 473.25 Td (to ) Tj ET Q q 0 0 0 rg BT 121.94 473.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 172.09 473.25 Td (execute ) Tj ET Q q 0 0 0 rg BT 204.45 473.25 Td (our ) Tj ET Q q 0 0 0 rg BT 220.73 473.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 262.01 473.25 Td (model ) Tj ET Q q 0 0 0 rg BT 288.83 473.25 Td (evolution ) Tj ET Q q 0 0 0 rg BT 328.43 473.25 Td (could ) Tj ET Q q 0 0 0 rg BT 353.04 473.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 382.64 473.25 Td (our ) Tj ET Q q 0 0 0 rg BT 398.92 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 402.44 473.25 Td (esults. ) Tj ET Q q 0 0 0 rg BT 430.11 473.25 Td (If ) Tj ET Q q 0 0 0 rg BT 438.60 473.25 Td (we ) Tj ET Q q 0 0 0 rg BT 452.10 473.25 Td (ar) Tj ET Q q 0 0 0 rg BT 460.62 473.25 Td (e ) Tj ET Q q 0 0 0 rg BT 467.45 473.25 Td (not ) Tj ET Q q 0 0 0 rg BT 482.61 473.25 Td (able ) Tj ET Q q 0 0 0 rg BT 502.22 473.25 Td (to ) Tj ET Q q 0 0 0 rg BT 512.38 473.25 Td (achieve ) Tj ET Q q 0 0 0 rg BT 545.30 473.25 Td (the ) Tj ET Q q 0 0 0 rg BT 559.91 473.25 Td (cost ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (savings ) Tj ET Q q 0 0 0 rg BT 68.11 461.25 Td (we ) Tj ET Q q 0 0 0 rg BT 81.33 461.25 Td (expect, ) Tj ET Q q 0 0 0 rg BT 111.47 461.25 Td (this ) Tj ET Q q 0 0 0 rg BT 128.03 461.25 Td (could ) Tj ET Q q 0 0 0 rg BT 152.36 461.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 195.56 461.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 224.89 461.25 Td (our ) Tj ET Q q 0 0 0 rg BT 240.89 461.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 281.89 461.25 Td (mar) Tj ET Q q 0 0 0 rg BT 297.63 461.25 Td (gin ) Tj ET Q q 0 0 0 rg BT 312.52 461.25 Td (and ) Tj ET Q q 0 0 0 rg BT 329.63 461.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 366.74 461.25 Td (r) Tj ET Q q 0 0 0 rg BT 370.26 461.25 Td (esults. ) Tj ET Q q 0 0 0 rg BT 397.65 461.25 Td (In ) Tj ET Q q 0 0 0 rg BT 408.09 461.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 446.04 461.25 Td (we ) Tj ET Q q 0 0 0 rg BT 459.26 461.25 Td (may ) Tj ET Q q 0 0 0 rg BT 478.03 461.25 Td (be ) Tj ET Q q 0 0 0 rg BT 489.58 461.25 Td (unable ) Tj ET Q q 0 0 0 rg BT 518.90 461.25 Td (to ) Tj ET Q q 0 0 0 rg BT 528.79 461.25 Td (consistently ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (maintain ) Tj ET Q q 0 0 0 rg BT 74.61 449.25 Td (an ) Tj ET Q q 0 0 0 rg BT 87.67 449.25 Td (adequate ) Tj ET Q q 0 0 0 rg BT 127.38 449.25 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 165.15 449.25 Td (thr) Tj ET Q q 0 0 0 rg BT 176.45 449.25 Td (ough ) Tj ET Q q 0 0 0 rg BT 199.51 449.25 Td (internal ) Tj ET Q q 0 0 0 rg BT 234.23 449.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 258.39 449.25 Td (pr) Tj ET Q q 0 0 0 rg BT 266.91 449.25 Td (ograms ) Tj ET Q q 0 0 0 rg BT 299.97 449.25 Td (or ) Tj ET Q q 0 0 0 rg BT 311.92 449.25 Td (transactions ) Tj ET Q q 0 0 0 rg BT 364.43 449.25 Td (with ) Tj ET Q q 0 0 0 rg BT 384.71 449.25 Td (thir) Tj ET Q q 0 0 0 rg BT 398.79 449.25 Td (d ) Tj ET Q q 0 0 0 rg BT 406.84 449.25 Td (parties, ) Tj ET Q q 0 0 0 rg BT 440.18 449.25 Td (to ) Tj ET Q q 0 0 0 rg BT 451.01 449.25 Td (support ) Tj ET Q q 0 0 0 rg BT 484.63 449.25 Td (futur) Tj ET Q q 0 0 0 rg BT 503.71 449.25 Td (e ) Tj ET Q q 0 0 0 rg BT 511.21 449.25 Td (r) Tj ET Q q 0 0 0 rg BT 514.73 449.25 Td (evenue ) Tj ET Q q 0 0 0 rg BT 545.54 449.25 Td (gr) Tj ET Q q 0 0 0 rg BT 554.06 449.25 Td (owth. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (Competition ) Tj ET Q q 0 0 0 rg BT 88.20 437.25 Td (among ) Tj ET Q q 0 0 0 rg BT 118.17 437.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 183.69 437.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 229.21 437.25 Td (for ) Tj ET Q q 0 0 0 rg BT 243.64 437.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 290.83 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 308.59 437.25 Td (pr) Tj ET Q q 0 0 0 rg BT 317.11 437.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 342.08 437.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 380.94 437.25 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 437.03 437.25 Td (is ) Tj ET Q q 0 0 0 rg BT 446.45 437.25 Td (intense, ) Tj ET Q q 0 0 0 rg BT 480.03 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 497.78 437.25 Td (we ) Tj ET Q q 0 0 0 rg BT 511.64 437.25 Td (may ) Tj ET Q q 0 0 0 rg BT 531.06 437.25 Td (not ) Tj ET Q q 0 0 0 rg BT 546.59 437.25 Td (be ) Tj ET Q q 0 0 0 rg BT 558.78 437.25 Td (able ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (to ) Tj ET Q q 0 0 0 rg BT 45.48 425.25 Td (locate ) Tj ET Q q 0 0 0 rg BT 71.61 425.25 Td (suitable ) Tj ET Q q 0 0 0 rg BT 104.98 425.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 151.12 425.25 Td (tar) Tj ET Q q 0 0 0 rg BT 162.42 425.25 Td (gets ) Tj ET Q q 0 0 0 rg BT 180.23 425.25 Td (or ) Tj ET Q q 0 0 0 rg BT 190.82 425.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 228.63 425.25 Td (partners ) Tj ET Q q 0 0 0 rg BT 264.22 425.25 Td (at ) Tj ET Q q 0 0 0 rg BT 273.70 425.25 Td (r) Tj ET Q q 0 0 0 rg BT 277.22 425.25 Td (easonable ) Tj ET Q q 0 0 0 rg BT 319.47 425.25 Td (prices, ) Tj ET Q q 0 0 0 rg BT 348.11 425.25 Td (or ) Tj ET Q q 0 0 0 rg BT 358.70 425.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 408.16 425.25 Td (execute ) Tj ET Q q 0 0 0 rg BT 439.83 425.25 Td (such ) Tj ET Q q 0 0 0 rg BT 459.86 425.25 Td (transactions. ) Tj ET Q q 0 0 0 rg BT 513.51 425.25 Td (If ) Tj ET Q q 0 0 0 rg BT 521.32 425.25 Td (we ) Tj ET Q q 0 0 0 rg BT 534.13 425.25 Td (ar) Tj ET Q q 0 0 0 rg BT 542.65 425.25 Td (e ) Tj ET Q q 0 0 0 rg BT 548.79 425.25 Td (unable ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 47.34 413.25 Td (support ) Tj ET Q q 0 0 0 rg BT 81.45 413.25 Td (and ) Tj ET Q q 0 0 0 rg BT 100.01 413.25 Td (gr) Tj ET Q q 0 0 0 rg BT 108.53 413.25 Td (ow ) Tj ET Q q 0 0 0 rg BT 123.76 413.25 Td (our ) Tj ET Q q 0 0 0 rg BT 141.21 413.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 181.97 413.25 Td (pr) Tj ET Q q 0 0 0 rg BT 190.49 413.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 222.66 413.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 273.98 413.25 Td (execute ) Tj ET Q q 0 0 0 rg BT 307.51 413.25 Td (the ) Tj ET Q q 0 0 0 rg BT 323.28 413.25 Td (launches ) Tj ET Q q 0 0 0 rg BT 362.38 413.25 Td (of ) Tj ET Q q 0 0 0 rg BT 373.72 413.25 Td (newly ) Tj ET Q q 0 0 0 rg BT 400.60 413.25 Td (appr) Tj ET Q q 0 0 0 rg BT 419.12 413.25 Td (oved ) Tj ET Q q 0 0 0 rg BT 441.56 413.25 Td (pr) Tj ET Q q 0 0 0 rg BT 450.08 413.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 482.24 413.25 Td (advance ) Tj ET Q q 0 0 0 rg BT 519.12 413.25 Td (our ) Tj ET Q q 0 0 0 rg BT 536.56 413.25 Td (late-stage ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 74.19 401.25 Td (manage ) Tj ET Q q 0 0 0 rg BT 109.33 401.25 Td (change ) Tj ET Q q 0 0 0 rg BT 141.69 401.25 Td (fr) Tj ET Q q 0 0 0 rg BT 147.99 401.25 Td (om ) Tj ET Q q 0 0 0 rg BT 163.69 401.25 Td (our ) Tj ET Q q 0 0 0 rg BT 181.06 401.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 223.43 401.25 Td (model ) Tj ET Q q 0 0 0 rg BT 251.35 401.25 Td (evolution ) Tj ET Q q 0 0 0 rg BT 292.04 401.25 Td (and ) Tj ET Q q 0 0 0 rg BT 310.52 401.25 Td (manage ) Tj ET Q q 0 0 0 rg BT 345.66 401.25 Td (our ) Tj ET Q q 0 0 0 rg BT 363.04 401.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 386.52 401.25 Td (effectively) Tj ET Q q 0 0 0 rg BT 426.49 401.25 Td (, ) Tj ET Q q 0 0 0 rg BT 432.47 401.25 Td (our ) Tj ET Q q 0 0 0 rg BT 449.84 401.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 492.21 401.25 Td (r) Tj ET Q q 0 0 0 rg BT 495.73 401.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 521.99 401.25 Td (and ) Tj ET Q q 0 0 0 rg BT 540.47 401.25 Td (financial ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (condition ) Tj ET Q q 0 0 0 rg BT 76.27 389.25 Td (could ) Tj ET Q q 0 0 0 rg BT 100.99 389.25 Td (be ) Tj ET Q q 0 0 0 rg BT 112.93 389.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 156.52 389.25 Td (impacted. ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 365.25 Td (Failure ) Tj ET Q q 0 0 0 rg BT 69.62 365.25 Td (to ) Tj ET Q q 0 0 0 rg BT 79.90 365.25 Td (attract ) Tj ET Q q 0 0 0 rg BT 109.06 365.25 Td (and ) Tj ET Q q 0 0 0 rg BT 127.12 365.25 Td (retain ) Tj ET Q q 0 0 0 rg BT 154.07 365.25 Td (highly ) Tj ET Q q 0 0 0 rg BT 182.69 365.25 Td (qualified ) Tj ET Q q 0 0 0 rg BT 221.85 365.25 Td (personnel ) Tj ET Q q 0 0 0 rg BT 264.92 365.25 Td (could ) Tj ET Q q 0 0 0 rg BT 290.19 365.25 Td (af) Tj ET Q q 0 0 0 rg BT 298.34 365.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 315.83 365.25 Td (our ) Tj ET Q q 0 0 0 rg BT 332.78 365.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 360.83 365.25 Td (to ) Tj ET Q q 0 0 0 rg BT 371.11 365.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 423.05 365.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 456.64 365.25 Td (and ) Tj ET Q q 0 0 0 rg BT 474.71 365.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 536.63 365.25 Td (products.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 55.14 353.25 Td (success ) Tj ET Q q 0 0 0 rg BT 88.15 353.25 Td (is ) Tj ET Q q 0 0 0 rg BT 97.85 353.25 Td (lar) Tj ET Q q 0 0 0 rg BT 109.15 353.25 Td (gely ) Tj ET Q q 0 0 0 rg BT 128.83 353.25 Td (dependent ) Tj ET Q q 0 0 0 rg BT 172.95 353.25 Td (on ) Tj ET Q q 0 0 0 rg BT 185.97 353.25 Td (our ) Tj ET Q q 0 0 0 rg BT 202.89 353.25 Td (continued ) Tj ET Q q 0 0 0 rg BT 245.35 353.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 273.92 353.25 Td (to ) Tj ET Q q 0 0 0 rg BT 284.73 353.25 Td (attract ) Tj ET Q q 0 0 0 rg BT 314.42 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 332.44 353.25 Td (r) Tj ET Q q 0 0 0 rg BT 335.96 353.25 Td (etain ) Tj ET Q q 0 0 0 rg BT 358.98 353.25 Td (highly ) Tj ET Q q 0 0 0 rg BT 387.00 353.25 Td (qualified ) Tj ET Q q 0 0 0 rg BT 425.58 353.25 Td (scientific, ) Tj ET Q q 0 0 0 rg BT 467.20 353.25 Td (technical ) Tj ET Q q 0 0 0 rg BT 506.88 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 524.90 353.25 Td (management ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (personnel, ) Tj ET Q q 0 0 0 rg BT 79.50 341.25 Td (as ) Tj ET Q q 0 0 0 rg BT 89.95 341.25 Td (well ) Tj ET Q q 0 0 0 rg BT 108.18 341.25 Td (as ) Tj ET Q q 0 0 0 rg BT 118.63 341.25 Td (personnel ) Tj ET Q q 0 0 0 rg BT 159.63 341.25 Td (with ) Tj ET Q q 0 0 0 rg BT 178.42 341.25 Td (expertise ) Tj ET Q q 0 0 0 rg BT 216.08 341.25 Td (in ) Tj ET Q q 0 0 0 rg BT 225.42 341.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 256.97 341.25 Td (R&D, ) Tj ET Q q 0 0 0 rg BT 282.14 341.25 Td (governmental ) Tj ET Q q 0 0 0 rg BT 338.68 341.25 Td (r) Tj ET Q q 0 0 0 rg BT 342.21 341.25 Td (egulation ) Tj ET Q q 0 0 0 rg BT 381.54 341.25 Td (and ) Tj ET Q q 0 0 0 rg BT 398.10 341.25 Td (commer) Tj ET Q q 0 0 0 rg BT 429.94 341.25 Td (cialization. ) Tj ET Q q 0 0 0 rg BT 476.23 341.25 Td (Competition ) Tj ET Q q 0 0 0 rg BT 527.23 341.25 Td (for ) Tj ET Q q 0 0 0 rg BT 540.46 341.25 Td (qualified ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 329.25 Td (personnel ) Tj ET Q q 0 0 0 rg BT 77.68 329.25 Td (in ) Tj ET Q q 0 0 0 rg BT 87.69 329.25 Td (the ) Tj ET Q q 0 0 0 rg BT 102.15 329.25 Td (biopharmaceutical ) Tj ET Q q 0 0 0 rg BT 179.93 329.25 Td (field ) Tj ET Q q 0 0 0 rg BT 199.94 329.25 Td (is ) Tj ET Q q 0 0 0 rg BT 208.85 329.25 Td (intense. ) Tj ET Q q 0 0 0 rg BT 241.91 329.25 Td (W) Tj ET Q q 0 0 0 rg BT 249.32 329.25 Td (e ) Tj ET Q q 0 0 0 rg BT 256.00 329.25 Td (cannot ) Tj ET Q q 0 0 0 rg BT 285.45 329.25 Td (be ) Tj ET Q q 0 0 0 rg BT 297.13 329.25 Td (sur) Tj ET Q q 0 0 0 rg BT 309.54 329.25 Td (e ) Tj ET Q q 0 0 0 rg BT 316.22 329.25 Td (that ) Tj ET Q q 0 0 0 rg BT 334.01 329.25 Td (we ) Tj ET Q q 0 0 0 rg BT 347.36 329.25 Td (will ) Tj ET Q q 0 0 0 rg BT 364.60 329.25 Td (be ) Tj ET Q q 0 0 0 rg BT 376.28 329.25 Td (able ) Tj ET Q q 0 0 0 rg BT 395.73 329.25 Td (to ) Tj ET Q q 0 0 0 rg BT 405.75 329.25 Td (attract ) Tj ET Q q 0 0 0 rg BT 434.65 329.25 Td (and ) Tj ET Q q 0 0 0 rg BT 451.89 329.25 Td (r) Tj ET Q q 0 0 0 rg BT 455.41 329.25 Td (etain ) Tj ET Q q 0 0 0 rg BT 477.64 329.25 Td (quality ) Tj ET Q q 0 0 0 rg BT 507.65 329.25 Td (personnel ) Tj ET Q q 0 0 0 rg BT 549.33 329.25 Td (or ) Tj ET Q q 0 0 0 rg BT 560.46 329.25 Td (that ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 317.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 317.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 73.22 317.25 Td (of ) Tj ET Q q 0 0 0 rg BT 83.50 317.25 Td (doing ) Tj ET Q q 0 0 0 rg BT 108.77 317.25 Td (so ) Tj ET Q q 0 0 0 rg BT 120.17 317.25 Td (will ) Tj ET Q q 0 0 0 rg BT 137.67 317.25 Td (not ) Tj ET Q q 0 0 0 rg BT 152.95 317.25 Td (materially ) Tj ET Q q 0 0 0 rg BT 196.55 317.25 Td (incr) Tj ET Q q 0 0 0 rg BT 212.29 317.25 Td (ease.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 293.25 Td (Any ) Tj ET Q q 0 0 0 rg BT 55.03 293.25 Td (businesses ) Tj ET Q q 0 0 0 rg BT 100.73 293.25 Td (or ) Tj ET Q q 0 0 0 rg BT 111.99 293.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 138.24 293.25 Td (we ) Tj ET Q q 0 0 0 rg BT 151.71 293.25 Td (acquire ) Tj ET Q q 0 0 0 rg BT 185.17 293.25 Td (in ) Tj ET Q q 0 0 0 rg BT 195.87 293.25 Td (the ) Tj ET Q q 0 0 0 rg BT 211.01 293.25 Td (future ) Tj ET Q q 0 0 0 rg BT 238.93 293.25 Td (may ) Tj ET Q q 0 0 0 rg BT 258.51 293.25 Td (underperform, ) Tj ET Q q 0 0 0 rg BT 321.15 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 339.07 293.25 Td (we ) Tj ET Q q 0 0 0 rg BT 352.54 293.25 Td (may ) Tj ET Q q 0 0 0 rg BT 372.12 293.25 Td (not ) Tj ET Q q 0 0 0 rg BT 387.82 293.25 Td (be ) Tj ET Q q 0 0 0 rg BT 399.62 293.25 Td (able ) Tj ET Q q 0 0 0 rg BT 419.19 293.25 Td (to ) Tj ET Q q 0 0 0 rg BT 429.33 293.25 Td (successfully ) Tj ET Q q 0 0 0 rg BT 481.13 293.25 Td (integrate ) Tj ET Q q 0 0 0 rg BT 520.16 293.25 Td (them ) Tj ET Q q 0 0 0 rg BT 543.07 293.25 Td (into ) Tj ET Q q 0 0 0 rg BT 561.55 293.25 Td (our ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 281.25 Td (existing ) Tj ET Q q 0 0 0 rg BT 70.73 281.25 Td (business.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 269.25 Td (An ) Tj ET Q q 0 0 0 rg BT 49.62 269.25 Td (essential ) Tj ET Q q 0 0 0 rg BT 87.13 269.25 Td (component ) Tj ET Q q 0 0 0 rg BT 133.52 269.25 Td (of ) Tj ET Q q 0 0 0 rg BT 143.81 269.25 Td (our ) Tj ET Q q 0 0 0 rg BT 160.21 269.25 Td (strategy ) Tj ET Q q 0 0 0 rg BT 194.94 269.25 Td (has ) Tj ET Q q 0 0 0 rg BT 211.34 269.25 Td (been ) Tj ET Q q 0 0 0 rg BT 232.73 269.25 Td (business ) Tj ET Q q 0 0 0 rg BT 269.14 269.25 Td (development ) Tj ET Q q 0 0 0 rg BT 322.18 269.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 360.79 269.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 393.29 269.25 Td (to ) Tj ET Q q 0 0 0 rg BT 403.58 269.25 Td (sour) Tj ET Q q 0 0 0 rg BT 420.99 269.25 Td (ce ) Tj ET Q q 0 0 0 rg BT 432.38 269.25 Td (innovation ) Tj ET Q q 0 0 0 rg BT 477.67 269.25 Td (externally ) Tj ET Q q 0 0 0 rg BT 520.16 269.25 Td (to ) Tj ET Q q 0 0 0 rg BT 530.45 269.25 Td (supplement ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 257.25 Td (our ) Tj ET Q q 0 0 0 rg BT 52.28 257.25 Td (own ) Tj ET Q q 0 0 0 rg BT 71.34 257.25 Td (discovery ) Tj ET Q q 0 0 0 rg BT 112.05 257.25 Td (and ) Tj ET Q q 0 0 0 rg BT 129.44 257.25 Td (development ) Tj ET Q q 0 0 0 rg BT 182.37 257.25 Td (efforts.  ) Tj ET Q q 0 0 0 rg BT 215.14 257.25 Td (As ) Tj ET Q q 0 0 0 rg BT 227.53 257.25 Td (such, ) Tj ET Q q 0 0 0 rg BT 250.76 257.25 Td (we ) Tj ET Q q 0 0 0 rg BT 264.26 257.25 Td (have ) Tj ET Q q 0 0 0 rg BT 285.52 257.25 Td (acquir) Tj ET Q q 0 0 0 rg BT 311.26 257.25 Td (ed, ) Tj ET Q q 0 0 0 rg BT 325.59 257.25 Td (or ) Tj ET Q q 0 0 0 rg BT 336.88 257.25 Td (in-licensed, ) Tj ET Q q 0 0 0 rg BT 385.64 257.25 Td (a ) Tj ET Q q 0 0 0 rg BT 393.03 257.25 Td (number ) Tj ET Q q 0 0 0 rg BT 425.97 257.25 Td (of ) Tj ET Q q 0 0 0 rg BT 436.14 257.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 462.43 257.25 Td (and ) Tj ET Q q 0 0 0 rg BT 479.82 257.25 Td (we ) Tj ET Q q 0 0 0 rg BT 493.32 257.25 Td (expect ) Tj ET Q q 0 0 0 rg BT 521.24 257.25 Td (to ) Tj ET Q q 0 0 0 rg BT 531.41 257.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 568.24 257.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 245.25 Td (support our ) Tj ET Q q 0 0 0 rg BT 85.55 245.25 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 120.37 245.25 Td (with ) Tj ET Q q 0 0 0 rg BT 140.19 245.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 188.34 245.25 Td (or ) Tj ET Q q 0 0 0 rg BT 199.84 245.25 Td (pr) Tj ET Q q 0 0 0 rg BT 208.36 245.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 237.06 245.25 Td (obtained ) Tj ET Q q 0 0 0 rg BT 274.66 245.25 Td (thr) Tj ET Q q 0 0 0 rg BT 285.96 245.25 Td (ough ) Tj ET Q q 0 0 0 rg BT 308.56 245.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 347.26 245.25 Td (and ) Tj ET Q q 0 0 0 rg BT 364.86 245.25 Td (acquisitions. ) Tj ET Q q 0 0 0 rg BT 418.30 245.25 Td (Futur) Tj ET Q q 0 0 0 rg BT 440.70 245.25 Td (e ) Tj ET Q q 0 0 0 rg BT 447.74 245.25 Td (r) Tj ET Q q 0 0 0 rg BT 451.26 245.25 Td (evenues, ) Tj ET Q q 0 0 0 rg BT 488.01 245.25 Td (pr) Tj ET Q q 0 0 0 rg BT 496.53 245.25 Td (ofits ) Tj ET Q q 0 0 0 rg BT 516.36 245.25 Td (and ) Tj ET Q q 0 0 0 rg BT 533.96 245.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 554.89 245.25 Td (flows ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 233.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.74 233.25 Td (an ) Tj ET Q q 0 0 0 rg BT 59.70 233.25 Td (acquir) Tj ET Q q 0 0 0 rg BT 85.44 233.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 97.84 233.25 Td (company’) Tj ET Q q 0 0 0 rg BT 135.98 233.25 Td (s ) Tj ET Q q 0 0 0 rg BT 142.84 233.25 Td (pr) Tj ET Q q 0 0 0 rg BT 151.36 233.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 182.93 233.25 Td (technologies ) Tj ET Q q 0 0 0 rg BT 236.43 233.25 Td (and ) Tj ET Q q 0 0 0 rg BT 254.40 233.25 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 289.57 233.25 Td (candidates, ) Tj ET Q q 0 0 0 rg BT 338.36 233.25 Td (may ) Tj ET Q q 0 0 0 rg BT 357.98 233.25 Td (not ) Tj ET Q q 0 0 0 rg BT 373.72 233.25 Td (materialize ) Tj ET Q q 0 0 0 rg BT 421.68 233.25 Td (due ) Tj ET Q q 0 0 0 rg BT 439.08 233.25 Td (to ) Tj ET Q q 0 0 0 rg BT 449.82 233.25 Td (low ) Tj ET Q q 0 0 0 rg BT 467.24 233.25 Td (pr) Tj ET Q q 0 0 0 rg BT 475.76 233.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 500.94 233.25 Td (uptake, ) Tj ET Q q 0 0 0 rg BT 533.05 233.25 Td (delayed ) Tj ET Q q 0 0 0 rg BT 567.11 233.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 221.25 Td (missed ) Tj ET Q q 0 0 0 rg BT 66.65 221.25 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 102.29 221.25 Td (opportunities, ) Tj ET Q q 0 0 0 rg BT 161.55 221.25 Td (the ) Tj ET Q q 0 0 0 rg BT 177.20 221.25 Td (inability ) Tj ET Q q 0 0 0 rg BT 213.95 221.25 Td (to ) Tj ET Q q 0 0 0 rg BT 225.16 221.25 Td (captur) Tj ET Q q 0 0 0 rg BT 250.90 221.25 Td (e ) Tj ET Q q 0 0 0 rg BT 258.76 221.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 297.16 221.25 Td (syner) Tj ET Q q 0 0 0 rg BT 318.45 221.25 Td (gies, ) Tj ET Q q 0 0 0 rg BT 340.49 221.25 Td (incr) Tj ET Q q 0 0 0 rg BT 356.22 221.25 Td (eased ) Tj ET Q q 0 0 0 rg BT 382.42 221.25 Td (competition, ) Tj ET Q q 0 0 0 rg BT 435.56 221.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 462.31 221.25 Td (concerns, ) Tj ET Q q 0 0 0 rg BT 504.34 221.25 Td (r) Tj ET Q q 0 0 0 rg BT 507.86 221.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 549.61 221.25 Td (issues, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 209.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 64.33 209.25 Td (chain ) Tj ET Q q 0 0 0 rg BT 88.77 209.25 Td (pr) Tj ET Q q 0 0 0 rg BT 97.29 209.25 Td (oblems ) Tj ET Q q 0 0 0 rg BT 127.84 209.25 Td (or ) Tj ET Q q 0 0 0 rg BT 138.95 209.25 Td (other ) Tj ET Q q 0 0 0 rg BT 162.28 209.25 Td (factors ) Tj ET Q q 0 0 0 rg BT 192.28 209.25 Td (beyond ) Tj ET Q q 0 0 0 rg BT 223.38 209.25 Td (our ) Tj ET Q q 0 0 0 rg BT 239.50 209.25 Td (contr) Tj ET Q q 0 0 0 rg BT 260.23 209.25 Td (ol. ) Tj ET Q q 0 0 0 rg BT 272.73 209.25 Td (For ) Tj ET Q q 0 0 0 rg BT 289.96 209.25 Td (example ) Tj ET Q q 0 0 0 rg BT 325.49 209.25 Td (we ) Tj ET Q q 0 0 0 rg BT 338.82 209.25 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 392.15 209.25 Td (the ) Tj ET Q q 0 0 0 rg BT 406.59 209.25 Td (development ) Tj ET Q q 0 0 0 rg BT 459.34 209.25 Td (of ) Tj ET Q q 0 0 0 rg BT 469.34 209.25 Td (FS102 ) Tj ET Q q 0 0 0 rg BT 497.67 209.25 Td (which ) Tj ET Q q 0 0 0 rg BT 523.78 209.25 Td (was ) Tj ET Q q 0 0 0 rg BT 541.56 209.25 Td (in ) Tj ET Q q 0 0 0 rg BT 551.56 209.25 Td (Phase ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 197.25 Td (I ) Tj ET Q q 0 0 0 rg BT 41.70 197.25 Td (development ) Tj ET Q q 0 0 0 rg BT 94.60 197.25 Td (for ) Tj ET Q q 0 0 0 rg BT 108.63 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 123.22 197.25 Td (tr) Tj ET Q q 0 0 0 rg BT 129.52 197.25 Td (eatment ) Tj ET Q q 0 0 0 rg BT 163.54 197.25 Td (of ) Tj ET Q q 0 0 0 rg BT 173.68 197.25 Td (br) Tj ET Q q 0 0 0 rg BT 182.21 197.25 Td (east ) Tj ET Q q 0 0 0 rg BT 200.68 197.25 Td (and ) Tj ET Q q 0 0 0 rg BT 218.05 197.25 Td (gastric ) Tj ET Q q 0 0 0 rg BT 248.19 197.25 Td (cancer) Tj ET Q q 0 0 0 rg BT 274.29 197.25 Td (, ) Tj ET Q q 0 0 0 rg BT 279.16 197.25 Td (and ) Tj ET Q q 0 0 0 rg BT 296.53 197.25 Td (consequently ) Tj ET Q q 0 0 0 rg BT 351.10 197.25 Td (did ) Tj ET Q q 0 0 0 rg BT 366.24 197.25 Td (not ) Tj ET Q q 0 0 0 rg BT 381.39 197.25 Td (exer) Tj ET Q q 0 0 0 rg BT 398.22 197.25 Td (cise ) Tj ET Q q 0 0 0 rg BT 416.14 197.25 Td (our ) Tj ET Q q 0 0 0 rg BT 432.40 197.25 Td (option ) Tj ET Q q 0 0 0 rg BT 460.32 197.25 Td (to ) Tj ET Q q 0 0 0 rg BT 470.46 197.25 Td (pur) Tj ET Q q 0 0 0 rg BT 483.99 197.25 Td (chase ) Tj ET Q q 0 0 0 rg BT 509.12 197.25 Td (F-Star ) Tj ET Q q 0 0 0 rg BT 537.43 197.25 Td (Alpha. ) Tj ET Q q 0 0 0 rg BT 566.01 197.25 Td (As ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 185.25 Td (a ) Tj ET Q q 0 0 0 rg BT 42.36 185.25 Td (r) Tj ET Q q 0 0 0 rg BT 45.88 185.25 Td (esult, ) Tj ET Q q 0 0 0 rg BT 68.63 185.25 Td (we ) Tj ET Q q 0 0 0 rg BT 81.11 185.25 Td (r) Tj ET Q q 0 0 0 rg BT 84.63 185.25 Td (ecor) Tj ET Q q 0 0 0 rg BT 102.02 185.25 Td (ded ) Tj ET Q q 0 0 0 rg BT 117.83 185.25 Td (an ) Tj ET Q q 0 0 0 rg BT 129.19 185.25 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 153.32 185.25 Td (char) Tj ET Q q 0 0 0 rg BT 171.28 185.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 182.08 185.25 Td (of ) Tj ET Q q 0 0 0 rg BT 191.23 185.25 Td ($75 ) Tj ET Q q 0 0 0 rg BT 207.59 185.25 Td (million. ) Tj ET Q q 0 0 0 rg BT 239.79 185.25 Td (Substantial ) Tj ET Q q 0 0 0 rg BT 286.16 185.25 Td (difficulties, ) Tj ET Q q 0 0 0 rg BT 332.24 185.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 353.60 185.25 Td (and ) Tj ET Q q 0 0 0 rg BT 369.97 185.25 Td (delays ) Tj ET Q q 0 0 0 rg BT 396.88 185.25 Td (could ) Tj ET Q q 0 0 0 rg BT 420.46 185.25 Td (r) Tj ET Q q 0 0 0 rg BT 423.98 185.25 Td (esult ) Tj ET Q q 0 0 0 rg BT 444.23 185.25 Td (fr) Tj ET Q q 0 0 0 rg BT 450.53 185.25 Td (om ) Tj ET Q q 0 0 0 rg BT 464.11 185.25 Td (integrating ) Tj ET Q q 0 0 0 rg BT 509.92 185.25 Td (our ) Tj ET Q q 0 0 0 rg BT 525.17 185.25 Td (acquisitions, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 173.25 Td (including ) Tj ET Q q 0 0 0 rg BT 77.42 173.25 Td (for ) Tj ET Q q 0 0 0 rg BT 92.74 173.25 Td (\(i\) R&D, ) Tj ET Q q 0 0 0 rg BT 131.93 173.25 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 196.96 173.25 Td (distribution, ) Tj ET Q q 0 0 0 rg BT 249.78 173.25 Td (sales, ) Tj ET Q q 0 0 0 rg BT 275.93 173.25 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 322.62 173.25 Td (pr) Tj ET Q q 0 0 0 rg BT 331.14 173.25 Td (omotion ) Tj ET Q q 0 0 0 rg BT 367.57 173.25 Td (and ) Tj ET Q q 0 0 0 rg BT 386.22 173.25 Td (information ) Tj ET Q q 0 0 0 rg BT 437.09 173.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 484.61 173.25 Td (activities; ) Tj ET Q q 0 0 0 rg BT 527.68 173.25 Td (\(ii\) policies, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 161.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 161.25 Td (ocedur) Tj ET Q q 0 0 0 rg BT 71.92 161.25 Td (es, ) Tj ET Q q 0 0 0 rg BT 85.25 161.25 Td (pr) Tj ET Q q 0 0 0 rg BT 93.77 161.25 Td (ocesses, ) Tj ET Q q 0 0 0 rg BT 128.76 161.25 Td (contr) Tj ET Q q 0 0 0 rg BT 149.50 161.25 Td (ols ) Tj ET Q q 0 0 0 rg BT 163.67 161.25 Td (and ) Tj ET Q q 0 0 0 rg BT 181.17 161.25 Td (compliance; ) Tj ET Q q 0 0 0 rg BT 233.09 161.25 Td (and ) Tj ET Q q 0 0 0 rg BT 250.59 161.25 Td (\(iii\) tax ) Tj ET Q q 0 0 0 rg BT 282.80 161.25 Td (considerations.) Tj ET Q endstream endobj 47 0 obj <> endobj 48 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (23) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 749.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.09 749.25 Td (could ) Tj ET Q q 0 0 0 rg BT 76.37 749.25 Td (experience ) Tj ET Q q 0 0 0 rg BT 123.29 749.25 Td (dif) Tj ET Q q 0 0 0 rg BT 134.22 749.25 Td (ficulties ) Tj ET Q q 0 0 0 rg BT 169.49 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 187.55 749.25 Td (delays ) Tj ET Q q 0 0 0 rg BT 215.60 749.25 Td (in ) Tj ET Q q 0 0 0 rg BT 226.44 749.25 Td (the ) Tj ET Q q 0 0 0 rg BT 241.72 749.25 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 308.96 749.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 359.26 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 377.32 749.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 395.93 749.25 Td (of ) Tj ET Q q 0 0 0 rg BT 406.76 749.25 Td (our ) Tj ET Q q 0 0 0 rg BT 423.71 749.25 Td (products.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.96 737.25 Td (pr) Tj ET Q q 0 0 0 rg BT 63.49 737.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 88.55 737.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 117.51 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 135.37 737.25 Td (r) Tj ET Q q 0 0 0 rg BT 138.89 737.25 Td (elated ) Tj ET Q q 0 0 0 rg BT 166.17 737.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 196.80 737.25 Td (access ) Tj ET Q q 0 0 0 rg BT 225.75 737.25 Td (could ) Tj ET Q q 0 0 0 rg BT 250.81 737.25 Td (be ) Tj ET Q q 0 0 0 rg BT 263.10 737.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 307.04 737.25 Td (impacted ) Tj ET Q q 0 0 0 rg BT 346.55 737.25 Td (by) Tj ET Q q 0 0 0 rg BT 355.44 737.25 Td (, ) Tj ET Q q 0 0 0 rg BT 360.79 737.25 Td (among ) Tj ET Q q 0 0 0 rg BT 390.86 737.25 Td (other ) Tj ET Q q 0 0 0 rg BT 414.82 737.25 Td (things: ) Tj ET Q q 0 0 0 rg BT 445.45 737.25 Td (\(i\) pr) Tj ET Q q 0 0 0 rg BT 465.91 737.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 490.98 737.25 Td (seizur) Tj ET Q q 0 0 0 rg BT 514.50 737.25 Td (es ) Tj ET Q q 0 0 0 rg BT 525.68 737.25 Td (or ) Tj ET Q q 0 0 0 rg BT 537.43 737.25 Td (r) Tj ET Q q 0 0 0 rg BT 540.95 737.25 Td (ecalls ) Tj ET Q q 0 0 0 rg BT 567.12 737.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (for) Tj ET Q q 0 0 0 rg BT 47.30 725.25 Td (ced ) Tj ET Q q 0 0 0 rg BT 63.18 725.25 Td (closings ) Tj ET Q q 0 0 0 rg BT 97.97 725.25 Td (of ) Tj ET Q q 0 0 0 rg BT 107.75 725.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 168.64 725.25 Td (plants; 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) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (\(viii\) other ) Tj ET Q q 0 0 0 rg BT 80.51 629.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 140.87 629.25 Td (or ) Tj ET Q q 0 0 0 rg BT 151.23 629.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 199.37 629.25 Td (issues, ) Tj ET Q q 0 0 0 rg BT 227.23 629.25 Td (including ) Tj ET Q q 0 0 0 rg BT 266.47 629.25 Td (limits ) Tj ET Q q 0 0 0 rg BT 290.17 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 299.42 629.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 359.77 629.25 Td (capacity ) Tj ET Q q 0 0 0 rg BT 395.11 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 411.58 629.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 445.82 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 455.06 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 468.75 629.25 Td (types ) Tj ET Q q 0 0 0 rg BT 490.77 629.25 Td (of ) Tj ET Q q 0 0 0 rg BT 500.01 629.25 Td (pr) Tj ET Q q 0 0 0 rg BT 508.53 629.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 536.11 629.25 Td (pr) Tj ET Q q 0 0 0 rg BT 544.63 629.25 Td (oduced, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (such ) Tj ET Q q 0 0 0 rg BT 57.61 617.25 Td (as ) Tj ET Q q 0 0 0 rg BT 69.77 617.25 Td (biologics, ) Tj ET Q q 0 0 0 rg BT 112.21 617.25 Td (physical ) Tj ET Q q 0 0 0 rg BT 148.81 617.25 Td (limitations ) Tj ET Q q 0 0 0 rg BT 194.87 617.25 Td (or ) Tj ET Q q 0 0 0 rg BT 207.04 617.25 Td (other ) Tj ET Q q 0 0 0 rg BT 231.42 617.25 Td (business ) Tj ET Q q 0 0 0 rg BT 268.59 617.25 Td (interruptions; ) Tj ET Q q 0 0 0 rg BT 327.42 617.25 Td (and ) Tj ET Q q 0 0 0 rg BT 345.70 617.25 Td (\(ix\) ) Tj ET Q q 0 0 0 rg BT 362.85 617.25 Td (disruption ) Tj ET Q q 0 0 0 rg BT 407.24 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 418.30 617.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 447.68 617.25 Td (chain ) Tj ET Q q 0 0 0 rg BT 473.17 617.25 Td (continuity ) Tj ET Q q 0 0 0 rg BT 516.44 617.25 Td (including ) Tj ET Q q 0 0 0 rg BT 557.49 617.25 Td (fr) Tj ET Q q 0 0 0 rg BT 563.79 617.25 Td (om ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (natural ) Tj ET Q q 0 0 0 rg BT 67.47 605.25 Td (disasters, ) Tj ET Q q 0 0 0 rg BT 107.55 605.25 Td (acts ) Tj ET Q q 0 0 0 rg BT 125.68 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 135.47 605.25 Td (war ) Tj ET Q q 0 0 0 rg BT 153.05 605.25 Td (or ) Tj ET Q q 0 0 0 rg BT 163.96 605.25 Td (terr) Tj ET Q q 0 0 0 rg BT 178.59 605.25 Td (orism ) Tj ET Q q 0 0 0 rg BT 203.40 605.25 Td (or ) Tj ET Q q 0 0 0 rg BT 214.31 605.25 Td (other ) Tj ET Q q 0 0 0 rg BT 237.43 605.25 Td (external ) Tj ET Q q 0 0 0 rg BT 272.22 605.25 Td (factors ) Tj ET Q q 0 0 0 rg BT 302.01 605.25 Td (over ) Tj ET Q q 0 0 0 rg BT 321.80 605.25 Td (which ) Tj ET Q q 0 0 0 rg BT 347.71 605.25 Td (we ) Tj ET Q q 0 0 0 rg BT 360.83 605.25 Td (have ) Tj ET Q q 0 0 0 rg BT 381.73 605.25 Td (no ) Tj ET Q q 0 0 0 rg BT 393.75 605.25 Td (contr) Tj ET Q q 0 0 0 rg BT 414.49 605.25 Td (ol ) Tj ET Q q 0 0 0 rg BT 424.28 605.25 Td (impacting ) Tj ET Q q 0 0 0 rg BT 466.30 605.25 Td (one ) Tj ET Q q 0 0 0 rg BT 482.76 605.25 Td (or ) Tj ET Q q 0 0 0 rg BT 493.67 605.25 Td (mor) Tj ET Q q 0 0 0 rg BT 509.41 605.25 Td (e ) Tj ET Q q 0 0 0 rg BT 515.87 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 525.66 605.25 Td (our ) Tj ET Q q 0 0 0 rg BT 541.57 605.25 Td (facilities ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (or ) Tj ET Q q 0 0 0 rg BT 47.65 593.25 Td (at ) Tj ET Q q 0 0 0 rg BT 58.19 593.25 Td (a ) Tj ET Q q 0 0 0 rg BT 65.94 593.25 Td (critical ) Tj ET Q q 0 0 0 rg BT 97.58 593.25 Td (supplier) Tj ET Q q 0 0 0 rg BT 129.25 593.25 Td (. ) Tj ET Q q 0 0 0 rg BT 134.51 593.25 Td (For ) Tj ET Q q 0 0 0 rg BT 152.27 593.25 Td (example, ) Tj ET Q q 0 0 0 rg BT 190.84 593.25 Td (our ) Tj ET Q q 0 0 0 rg BT 207.49 593.25 Td (new ) Tj ET Q q 0 0 0 rg BT 226.36 593.25 Td (biologics ) Tj ET Q q 0 0 0 rg BT 265.78 593.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 327.42 593.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 357.95 593.25 Td (in ) Tj ET Q q 0 0 0 rg BT 368.49 593.25 Td (Cruiserath, ) Tj ET Q q 0 0 0 rg BT 417.08 593.25 Td (Ir) Tj ET Q q 0 0 0 rg BT 423.94 593.25 Td (eland ) Tj ET Q q 0 0 0 rg BT 448.91 593.25 Td (is ) Tj ET Q q 0 0 0 rg BT 458.34 593.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 496.07 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 506.60 593.25 Td (be ) Tj ET Q q 0 0 0 rg BT 518.80 593.25 Td (operational ) Tj ET Q q 0 0 0 rg BT 568.22 593.25 Td (in ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (2019. ) Tj ET Q q 0 0 0 rg BT 60.48 581.25 Td (A) Tj ET Q q 0 0 0 rg BT 66.41 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 68.55 581.25 Td (delay ) Tj ET Q q 0 0 0 rg BT 92.34 581.25 Td (in ) Tj ET Q q 0 0 0 rg BT 102.26 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 116.62 581.25 Td (planned ) Tj ET Q q 0 0 0 rg BT 150.97 581.25 Td (opening ) Tj ET Q q 0 0 0 rg BT 185.33 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 195.24 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 209.60 581.25 Td (site ) Tj ET Q q 0 0 0 rg BT 225.63 581.25 Td (could ) Tj ET Q q 0 0 0 rg BT 249.98 581.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 279.34 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 293.69 581.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 321.94 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 331.86 581.25 Td (our ) Tj ET Q q 0 0 0 rg BT 347.89 581.25 Td (pr) Tj ET Q q 0 0 0 rg BT 356.41 581.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 384.65 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 395.68 581.25 Td (r) Tj ET Q q 0 0 0 rg BT 399.20 581.25 Td (equir) Tj ET Q q 0 0 0 rg BT 419.94 581.25 Td (e ) Tj ET Q q 0 0 0 rg BT 426.52 581.25 Td (us ) Tj ET Q q 0 0 0 rg BT 437.55 581.25 Td (to ) Tj ET Q q 0 0 0 rg BT 447.47 581.25 Td (obtain ) Tj ET Q q 0 0 0 rg BT 475.16 581.25 Td (pr) Tj ET Q q 0 0 0 rg BT 483.68 581.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 508.04 581.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 536.28 581.25 Td (fr) Tj ET Q q 0 0 0 rg BT 542.58 581.25 Td (om ) Tj ET Q q 0 0 0 rg BT 556.94 581.25 Td (thir) Tj ET Q q 0 0 0 rg BT 571.02 581.25 Td (d ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 66.28 569.25 Td (at ) Tj ET Q q 0 0 0 rg BT 76.56 569.25 Td (a ) Tj ET Q q 0 0 0 rg BT 84.06 569.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 128.78 569.25 Td (cost.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 55.17 545.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 117.12 545.25 Td (and ) Tj ET Q q 0 0 0 rg BT 135.18 545.25 Td (commer) Tj ET Q q 0 0 0 rg BT 167.02 545.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 185.08 545.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 230.92 545.25 Td (in ) Tj ET Q q 0 0 0 rg BT 241.76 545.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 272.03 545.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 293.42 545.25 Td (wer) Tj ET Q q 0 0 0 rg BT 308.05 545.25 Td (e ) Tj ET Q q 0 0 0 rg BT 315.55 545.25 Td (impacted ) Tj ET Q q 0 0 0 rg BT 355.26 545.25 Td (by ) Tj ET Q q 0 0 0 rg BT 367.76 545.25 Td (the ) Tj ET Q q 0 0 0 rg BT 383.04 545.25 Td (r) Tj ET Q q 0 0 0 rg BT 386.56 545.25 Td (ecent ) Tj ET Q q 0 0 0 rg BT 410.71 545.25 Td (hurricanes. ) Tj ET Q q 0 0 0 rg BT 459.60 545.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 478.78 545.25 Td (two ) Tj ET Q q 0 0 0 rg BT 496.29 545.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 558.23 545.25 Td (sites ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (sustained ) Tj ET Q q 0 0 0 rg BT 75.83 533.25 Td (some ) Tj ET Q q 0 0 0 rg BT 98.43 533.25 Td (damage ) Tj ET Q q 0 0 0 rg BT 132.14 533.25 Td (but ) Tj ET Q q 0 0 0 rg BT 146.97 533.25 Td (ar) Tj ET Q q 0 0 0 rg BT 155.49 533.25 Td (e ) Tj ET Q q 0 0 0 rg BT 161.98 533.25 Td (curr) Tj ET Q q 0 0 0 rg BT 178.83 533.25 Td (ently ) Tj ET Q q 0 0 0 rg BT 200.32 533.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 241.25 533.25 Td (at ) Tj ET Q q 0 0 0 rg BT 251.08 533.25 Td (r) Tj ET Q q 0 0 0 rg BT 254.60 533.25 Td (educed ) Tj ET Q q 0 0 0 rg BT 284.97 533.25 Td (capacity) Tj ET Q q 0 0 0 rg BT 318.29 533.25 Td (. ) Tj ET Q q 0 0 0 rg BT 322.84 533.25 Td (W) Tj ET Q q 0 0 0 rg BT 330.25 533.25 Td (e ) Tj ET Q q 0 0 0 rg BT 336.74 533.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 373.23 533.25 Td (to ) Tj ET Q q 0 0 0 rg BT 383.06 533.25 Td (work ) Tj ET Q q 0 0 0 rg BT 405.11 533.25 Td (to ) Tj ET Q q 0 0 0 rg BT 414.94 533.25 Td (r) Tj ET Q q 0 0 0 rg BT 418.46 533.25 Td (estor) Tj ET Q q 0 0 0 rg BT 438.08 533.25 Td (e ) Tj ET Q q 0 0 0 rg BT 444.57 533.25 Td (to ) Tj ET Q q 0 0 0 rg BT 454.40 533.25 Td (normal ) Tj ET Q q 0 0 0 rg BT 485.35 533.25 Td (operations. ) Tj ET Q q 0 0 0 rg BT 532.67 533.25 Td (Disruption ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.06 521.25 Td (our ) Tj ET Q q 0 0 0 rg BT 62.22 521.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 90.05 521.25 Td (to ) Tj ET Q q 0 0 0 rg BT 100.11 521.25 Td (operate ) Tj ET Q q 0 0 0 rg BT 132.93 521.25 Td (our ) Tj ET Q q 0 0 0 rg BT 149.10 521.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 178.59 521.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 199.20 521.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 260.36 521.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 297.07 521.25 Td (\(whether ) Tj ET Q q 0 0 0 rg BT 334.90 521.25 Td (due ) Tj ET Q q 0 0 0 rg BT 351.61 521.25 Td (to ) Tj ET Q q 0 0 0 rg BT 361.67 521.25 Td (pr) Tj ET Q q 0 0 0 rg BT 370.19 521.25 Td (oblems ) Tj ET Q q 0 0 0 rg BT 400.80 521.25 Td (with ) Tj ET Q q 0 0 0 rg BT 420.30 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 434.79 521.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 464.84 521.25 Td (itself, ) Tj ET Q q 0 0 0 rg BT 489.06 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 503.55 521.25 Td (infrastructur) Tj ET Q q 0 0 0 rg BT 554.30 521.25 Td (e ) Tj ET Q q 0 0 0 rg BT 561.01 521.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (services ) Tj ET Q q 0 0 0 rg BT 70.26 509.25 Td (available ) Tj ET Q q 0 0 0 rg BT 109.52 509.25 Td (on ) Tj ET Q q 0 0 0 rg BT 121.57 509.25 Td (the ) Tj ET Q q 0 0 0 rg BT 135.83 509.25 Td (island, ) Tj ET Q q 0 0 0 rg BT 164.83 509.25 Td (the ) Tj ET Q q 0 0 0 rg BT 179.10 509.25 Td (unavailability ) Tj ET Q q 0 0 0 rg BT 236.70 509.25 Td (of ) Tj ET Q q 0 0 0 rg BT 246.52 509.25 Td (raw ) Tj ET Q q 0 0 0 rg BT 264.14 509.25 Td (materials ) Tj ET Q q 0 0 0 rg BT 303.96 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 314.91 509.25 Td (supplies ) Tj ET Q q 0 0 0 rg BT 349.73 509.25 Td (fr) Tj ET Q q 0 0 0 rg BT 356.03 509.25 Td (om ) Tj ET Q q 0 0 0 rg BT 370.30 509.25 Td (vendors, ) Tj ET Q q 0 0 0 rg BT 406.51 509.25 Td (the ) Tj ET Q q 0 0 0 rg BT 420.78 509.25 Td (unavailability ) Tj ET Q q 0 0 0 rg BT 478.38 509.25 Td (of ) Tj ET Q q 0 0 0 rg BT 488.21 509.25 Td (key ) Tj ET Q q 0 0 0 rg BT 503.57 509.25 Td (staff ) Tj ET Q q 0 0 0 rg BT 522.85 509.25 Td (or ) Tj ET Q q 0 0 0 rg BT 533.79 509.25 Td (otherwise\) ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (could ) Tj ET Q q 0 0 0 rg BT 60.72 497.25 Td (materially ) Tj ET Q q 0 0 0 rg BT 104.32 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 121.82 497.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 162.64 497.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 187.35 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 203.74 497.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 231.79 497.25 Td (to ) Tj ET Q q 0 0 0 rg BT 242.07 497.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 270.68 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 287.07 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 295.59 497.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 324.20 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 341.70 497.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 366.41 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 382.80 497.25 Td (pr) Tj ET Q q 0 0 0 rg BT 391.32 497.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 416.04 497.25 Td (sales.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (Product ) Tj ET Q q 0 0 0 rg BT 71.28 473.25 Td (labeling ) Tj ET Q q 0 0 0 rg BT 107.11 473.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 143.50 473.25 Td (for ) Tj ET Q q 0 0 0 rg BT 158.23 473.25 Td (our ) Tj ET Q q 0 0 0 rg BT 175.18 473.25 Td (marketed ) Tj ET Q q 0 0 0 rg BT 216.00 473.25 Td (products ) Tj ET Q q 0 0 0 rg BT 254.07 473.25 Td (could ) Tj ET Q q 0 0 0 rg BT 279.34 473.25 Td (result ) Tj ET Q q 0 0 0 rg BT 305.18 473.25 Td (in ) Tj ET Q q 0 0 0 rg BT 316.02 473.25 Td (a ) Tj ET Q q 0 0 0 rg BT 323.52 473.25 Td (negative ) Tj ET Q q 0 0 0 rg BT 360.46 473.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 390.73 473.25 Td (on ) Tj ET Q q 0 0 0 rg BT 403.79 473.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 442.95 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 461.01 473.25 Td (profit ) Tj ET Q q 0 0 0 rg BT 486.29 473.25 Td (margins.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 461.25 Td (e ) Tj ET Q q 0 0 0 rg BT 49.47 461.25 Td (or ) Tj ET Q q 0 0 0 rg BT 59.98 461.25 Td (r) Tj ET Q q 0 0 0 rg BT 63.50 461.25 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 103.45 461.25 Td (authorities ) Tj ET Q q 0 0 0 rg BT 148.41 461.25 Td (may ) Tj ET Q q 0 0 0 rg BT 166.69 461.25 Td (need ) Tj ET Q q 0 0 0 rg BT 187.19 461.25 Td (to ) Tj ET Q q 0 0 0 rg BT 196.59 461.25 Td (change ) Tj ET Q q 0 0 0 rg BT 227.08 461.25 Td (the ) Tj ET Q q 0 0 0 rg BT 240.92 461.25 Td (labeling ) Tj ET Q q 0 0 0 rg BT 275.32 461.25 Td (for ) Tj ET Q q 0 0 0 rg BT 288.61 461.25 Td (any ) Tj ET Q q 0 0 0 rg BT 304.67 461.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 369.05 461.25 Td (pr) Tj ET Q q 0 0 0 rg BT 377.57 461.25 Td (oduct, ) Tj ET Q q 0 0 0 rg BT 403.91 461.25 Td (including ) Tj ET Q q 0 0 0 rg BT 443.30 461.25 Td (after ) Tj ET Q q 0 0 0 rg BT 463.81 461.25 Td (a ) Tj ET Q q 0 0 0 rg BT 470.43 461.25 Td (pr) Tj ET Q q 0 0 0 rg BT 478.95 461.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 502.79 461.25 Td (has ) Tj ET Q q 0 0 0 rg BT 518.30 461.25 Td (been ) Tj ET Q q 0 0 0 rg BT 538.80 461.25 Td (marketed ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (for ) Tj ET Q q 0 0 0 rg BT 49.67 449.25 Td (several ) Tj ET Q q 0 0 0 rg BT 80.54 449.25 Td (years. ) Tj ET Q q 0 0 0 rg BT 106.70 449.25 Td (These ) Tj ET Q q 0 0 0 rg BT 132.02 449.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 166.79 449.25 Td (ar) Tj ET Q q 0 0 0 rg BT 175.31 449.25 Td (e ) Tj ET Q q 0 0 0 rg BT 181.74 449.25 Td (often ) Tj ET Q q 0 0 0 rg BT 203.73 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 217.95 449.25 Td (r) Tj ET Q q 0 0 0 rg BT 221.47 449.25 Td (esult ) Tj ET Q q 0 0 0 rg BT 242.35 449.25 Td (of ) Tj ET Q q 0 0 0 rg BT 252.12 449.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 295.23 449.25 Td (data ) Tj ET Q q 0 0 0 rg BT 315.01 449.25 Td (fr) Tj ET Q q 0 0 0 rg BT 321.31 449.25 Td (om ) Tj ET Q q 0 0 0 rg BT 335.52 449.25 Td (post-marketing ) Tj ET Q q 0 0 0 rg BT 398.07 449.25 Td (studies, ) Tj ET Q q 0 0 0 rg BT 430.34 449.25 Td (head-to-head ) Tj ET Q q 0 0 0 rg BT 485.65 449.25 Td (studies, ) Tj ET Q q 0 0 0 rg BT 517.93 449.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 551.02 449.25 Td (events ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 437.25 Td (eports, ) Tj ET Q q 0 0 0 rg BT 69.97 437.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 100.70 437.25 Td (that ) Tj ET Q q 0 0 0 rg BT 119.21 437.25 Td (identify ) Tj ET Q q 0 0 0 rg BT 152.15 437.25 Td (biomarkers ) Tj ET Q q 0 0 0 rg BT 200.66 437.25 Td (\(objective ) Tj ET Q q 0 0 0 rg BT 243.03 437.25 Td (characteristics ) Tj ET Q q 0 0 0 rg BT 305.41 437.25 Td (that ) Tj ET Q q 0 0 0 rg BT 323.92 437.25 Td (can ) Tj ET Q q 0 0 0 rg BT 341.31 437.25 Td (indicate ) Tj ET Q q 0 0 0 rg BT 376.47 437.25 Td (a ) Tj ET Q q 0 0 0 rg BT 384.43 437.25 Td (particular ) Tj ET Q q 0 0 0 rg BT 427.93 437.25 Td (r) Tj ET Q q 0 0 0 rg BT 431.45 437.25 Td (esponse ) Tj ET Q q 0 0 0 rg BT 466.07 437.25 Td (to ) Tj ET Q q 0 0 0 rg BT 476.80 437.25 Td (a ) Tj ET Q q 0 0 0 rg BT 484.75 437.25 Td (pr) Tj ET Q q 0 0 0 rg BT 493.27 437.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 518.44 437.25 Td (or ) Tj ET Q q 0 0 0 rg BT 530.28 437.25 Td (therapy\) ) Tj ET Q q 0 0 0 rg BT 567.11 437.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (other ) Tj ET Q q 0 0 0 rg BT 59.43 425.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 89.52 425.25 Td (or ) Tj ET Q q 0 0 0 rg BT 100.73 425.25 Td (post-marketing ) Tj ET Q q 0 0 0 rg BT 163.60 425.25 Td (experience ) Tj ET Q q 0 0 0 rg BT 209.22 425.25 Td (that ) Tj ET Q q 0 0 0 rg BT 227.09 425.25 Td (pr) Tj ET Q q 0 0 0 rg BT 235.61 425.25 Td (oduce ) Tj ET Q q 0 0 0 rg BT 261.81 425.25 Td (important ) Tj ET Q q 0 0 0 rg BT 303.58 425.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 347.01 425.25 Td (information ) Tj ET Q q 0 0 0 rg BT 396.55 425.25 Td (about ) Tj ET Q q 0 0 0 rg BT 421.65 425.25 Td (a ) Tj ET Q q 0 0 0 rg BT 428.97 425.25 Td (pr) Tj ET Q q 0 0 0 rg BT 437.49 425.25 Td (oduct. ) Tj ET Q q 0 0 0 rg BT 464.52 425.25 Td (New ) Tj ET Q q 0 0 0 rg BT 484.62 425.25 Td (information ) Tj ET Q q 0 0 0 rg BT 534.16 425.25 Td (added ) Tj ET Q q 0 0 0 rg BT 560.92 425.25 Td (to ) Tj ET Q q 0 0 0 rg BT 571.02 425.25 Td (a ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 413.25 Td (oduct’) Tj ET Q q 0 0 0 rg BT 68.78 413.25 Td (s ) Tj ET Q q 0 0 0 rg BT 74.49 413.25 Td (label ) Tj ET Q q 0 0 0 rg BT 96.31 413.25 Td (can ) Tj ET Q q 0 0 0 rg BT 112.57 413.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 136.60 413.25 Td (its ) Tj ET Q q 0 0 0 rg BT 147.87 413.25 Td (risk-benefit ) Tj ET Q q 0 0 0 rg BT 195.23 413.25 Td (pr) Tj ET Q q 0 0 0 rg BT 203.75 413.25 Td (ofile, ) Tj ET Q q 0 0 0 rg BT 225.85 413.25 Td (leading ) Tj ET Q q 0 0 0 rg BT 257.67 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 267.26 413.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 304.64 413.25 Td (r) Tj ET Q q 0 0 0 rg BT 308.16 413.25 Td (ecalls, ) Tj ET Q q 0 0 0 rg BT 335.80 413.25 Td (withdrawals ) Tj ET Q q 0 0 0 rg BT 387.08 413.25 Td (or ) Tj ET Q q 0 0 0 rg BT 397.80 413.25 Td (declining ) Tj ET Q q 0 0 0 rg BT 436.83 413.25 Td (r) Tj ET Q q 0 0 0 rg BT 440.35 413.25 Td (evenue, ) Tj ET Q q 0 0 0 rg BT 472.43 413.25 Td (as ) Tj ET Q q 0 0 0 rg BT 483.14 413.25 Td (well ) Tj ET Q q 0 0 0 rg BT 501.63 413.25 Td (as ) Tj ET Q q 0 0 0 rg BT 512.34 413.25 Td (pr) Tj ET Q q 0 0 0 rg BT 520.86 413.25 Td (oduct ) Tj ET Q q 0 0 0 rg BT 544.90 413.25 Td (liability ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (claims. ) Tj ET Q q 0 0 0 rg BT 66.89 401.25 Td (Sometimes ) Tj ET Q q 0 0 0 rg BT 111.94 401.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 155.34 401.25 Td (information ) Tj ET Q q 0 0 0 rg BT 204.84 401.25 Td (fr) Tj ET Q q 0 0 0 rg BT 211.14 401.25 Td (om ) Tj ET Q q 0 0 0 rg BT 225.65 401.25 Td (these ) Tj ET Q q 0 0 0 rg BT 248.47 401.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 278.53 401.25 Td (identifies ) Tj ET Q q 0 0 0 rg BT 317.48 401.25 Td (a ) Tj ET Q q 0 0 0 rg BT 324.76 401.25 Td (portion ) Tj ET Q q 0 0 0 rg BT 356.49 401.25 Td (of ) Tj ET Q q 0 0 0 rg BT 366.55 401.25 Td (the ) Tj ET Q q 0 0 0 rg BT 381.05 401.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 411.10 401.25 Td (population ) Tj ET Q q 0 0 0 rg BT 456.72 401.25 Td (that ) Tj ET Q q 0 0 0 rg BT 474.56 401.25 Td (may ) Tj ET Q q 0 0 0 rg BT 493.50 401.25 Td (be ) Tj ET Q q 0 0 0 rg BT 505.22 401.25 Td (non-r) Tj ET Q q 0 0 0 rg BT 527.07 401.25 Td (esponsive ) Tj ET Q q 0 0 0 rg BT 568.23 401.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (a ) Tj ET Q q 0 0 0 rg BT 43.31 389.25 Td (medicine ) Tj ET Q q 0 0 0 rg BT 81.71 389.25 Td (or ) Tj ET Q q 0 0 0 rg BT 92.90 389.25 Td (would ) Tj ET Q q 0 0 0 rg BT 119.66 389.25 Td (be ) Tj ET Q q 0 0 0 rg BT 131.40 389.25 Td (at ) Tj ET Q q 0 0 0 rg BT 141.49 389.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 169.90 389.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 187.21 389.25 Td (of ) Tj ET Q q 0 0 0 rg BT 197.29 389.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 230.70 389.25 Td (r) Tj ET Q q 0 0 0 rg BT 234.22 389.25 Td (eactions ) Tj ET Q q 0 0 0 rg BT 269.85 389.25 Td (and ) Tj ET Q q 0 0 0 rg BT 287.16 389.25 Td (labeling ) Tj ET Q q 0 0 0 rg BT 322.23 389.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 357.31 389.25 Td (based ) Tj ET Q q 0 0 0 rg BT 382.95 389.25 Td (on ) Tj ET Q q 0 0 0 rg BT 395.25 389.25 Td (such ) Tj ET Q q 0 0 0 rg BT 415.89 389.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 445.97 389.25 Td (may ) Tj ET Q q 0 0 0 rg BT 464.94 389.25 Td (limit ) Tj ET Q q 0 0 0 rg BT 485.58 389.25 Td (the ) Tj ET Q q 0 0 0 rg BT 500.10 389.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 530.18 389.25 Td (population. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 377.25 Td (The ) Tj ET Q q 0 0 0 rg BT 53.49 377.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 83.75 377.25 Td (pr) Tj ET Q q 0 0 0 rg BT 92.27 377.25 Td (oviding ) Tj ET Q q 0 0 0 rg BT 124.76 377.25 Td (such ) Tj ET Q q 0 0 0 rg BT 145.58 377.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 189.18 377.25 Td (information ) Tj ET Q q 0 0 0 rg BT 238.89 377.25 Td (may ) Tj ET Q q 0 0 0 rg BT 258.04 377.25 Td (be ) Tj ET Q q 0 0 0 rg BT 269.96 377.25 Td (sponsor) Tj ET Q q 0 0 0 rg BT 301.27 377.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 313.19 377.25 Td (by ) Tj ET Q q 0 0 0 rg BT 325.12 377.25 Td (us, ) Tj ET Q q 0 0 0 rg BT 339.00 377.25 Td (but ) Tj ET Q q 0 0 0 rg BT 354.27 377.25 Td (they ) Tj ET Q q 0 0 0 rg BT 373.41 377.25 Td (could ) Tj ET Q q 0 0 0 rg BT 398.11 377.25 Td (also ) Tj ET Q q 0 0 0 rg BT 417.27 377.25 Td (be ) Tj ET Q q 0 0 0 rg BT 429.20 377.25 Td (sponsor) Tj ET Q q 0 0 0 rg BT 460.50 377.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 472.43 377.25 Td (by ) Tj ET Q q 0 0 0 rg BT 484.35 377.25 Td (competitors, ) Tj ET Q q 0 0 0 rg BT 536.56 377.25 Td (insurance ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 365.25 Td (companies, ) Tj ET Q q 0 0 0 rg BT 83.75 365.25 Td (government ) Tj ET Q q 0 0 0 rg BT 133.44 365.25 Td (institutions, ) Tj ET Q q 0 0 0 rg BT 182.87 365.25 Td (managed ) Tj ET Q q 0 0 0 rg BT 222.02 365.25 Td (car) Tj ET Q q 0 0 0 rg BT 234.98 365.25 Td (e ) Tj ET Q q 0 0 0 rg BT 241.90 365.25 Td (or) Tj ET Q q 0 0 0 rg BT 250.42 365.25 Td (ganizations, ) Tj ET Q q 0 0 0 rg BT 301.52 365.25 Td (scientists, ) Tj ET Q q 0 0 0 rg BT 343.16 365.25 Td (investigators, ) Tj ET Q q 0 0 0 rg BT 399.81 365.25 Td (or ) Tj ET Q q 0 0 0 rg BT 411.18 365.25 Td (other ) Tj ET Q q 0 0 0 rg BT 434.77 365.25 Td (inter) Tj ET Q q 0 0 0 rg BT 453.29 365.25 Td (ested ) Tj ET Q q 0 0 0 rg BT 476.32 365.25 Td (parties. ) Tj ET Q q 0 0 0 rg BT 509.08 365.25 Td (While ) Tj ET Q q 0 0 0 rg BT 534.89 365.25 Td (additional ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 62.05 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 79.77 353.25 Td (efficacy ) Tj ET Q q 0 0 0 rg BT 113.58 353.25 Td (information ) Tj ET Q q 0 0 0 rg BT 163.54 353.25 Td (fr) Tj ET Q q 0 0 0 rg BT 169.83 353.25 Td (om ) Tj ET Q q 0 0 0 rg BT 184.78 353.25 Td (such ) Tj ET Q q 0 0 0 rg BT 205.83 353.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 236.33 353.25 Td (assist ) Tj ET Q q 0 0 0 rg BT 261.29 353.25 Td (us ) Tj ET Q q 0 0 0 rg BT 272.91 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 290.63 353.25 Td (healthcar) Tj ET Q q 0 0 0 rg BT 328.58 353.25 Td (e ) Tj ET Q q 0 0 0 rg BT 335.75 353.25 Td (pr) Tj ET Q q 0 0 0 rg BT 344.27 353.25 Td (oviders ) Tj ET Q q 0 0 0 rg BT 376.43 353.25 Td (in ) Tj ET Q q 0 0 0 rg BT 386.93 353.25 Td (identifying ) Tj ET Q q 0 0 0 rg BT 432.42 353.25 Td (the ) Tj ET Q q 0 0 0 rg BT 447.36 353.25 Td (best ) Tj ET Q q 0 0 0 rg BT 466.19 353.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 496.69 353.25 Td (population ) Tj ET Q q 0 0 0 rg BT 542.75 353.25 Td (for ) Tj ET Q q 0 0 0 rg BT 557.14 353.25 Td (each ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 341.25 Td (oduct, ) Tj ET Q q 0 0 0 rg BT 72.82 341.25 Td (it ) Tj ET Q q 0 0 0 rg BT 81.96 341.25 Td (can ) Tj ET Q q 0 0 0 rg BT 99.98 341.25 Td (also ) Tj ET Q q 0 0 0 rg BT 120.23 341.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 164.90 341.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 195.70 341.25 Td (our ) Tj ET Q q 0 0 0 rg BT 213.17 341.25 Td (r) Tj ET Q q 0 0 0 rg BT 216.69 341.25 Td (evenues ) Tj ET Q q 0 0 0 rg BT 251.92 341.25 Td (due ) Tj ET Q q 0 0 0 rg BT 269.94 341.25 Td (to ) Tj ET Q q 0 0 0 rg BT 281.30 341.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 322.64 341.25 Td (r) Tj ET Q q 0 0 0 rg BT 326.16 341.25 Td (eturns ) Tj ET Q q 0 0 0 rg BT 354.75 341.25 Td (and ) Tj ET Q q 0 0 0 rg BT 373.33 341.25 Td (a ) Tj ET Q q 0 0 0 rg BT 381.91 341.25 Td (mor) Tj ET Q q 0 0 0 rg BT 397.65 341.25 Td (e ) Tj ET Q q 0 0 0 rg BT 405.67 341.25 Td (limited ) Tj ET Q q 0 0 0 rg BT 437.03 341.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 468.38 341.25 Td (population ) Tj ET Q q 0 0 0 rg BT 515.30 341.25 Td (going ) Tj ET Q q 0 0 0 rg BT 541.66 341.25 Td (forwar) Tj ET Q q 0 0 0 rg BT 568.52 341.25 Td (d. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 329.25 Td (Additionally) Tj ET Q q 0 0 0 rg BT 84.89 329.25 Td (, ) Tj ET Q q 0 0 0 rg BT 90.63 329.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 122.20 329.25 Td (study ) Tj ET Q q 0 0 0 rg BT 146.55 329.25 Td (r) Tj ET Q q 0 0 0 rg BT 150.07 329.25 Td (esults, ) Tj ET Q q 0 0 0 rg BT 178.60 329.25 Td (especially ) Tj ET Q q 0 0 0 rg BT 221.82 329.25 Td (fr) Tj ET Q q 0 0 0 rg BT 228.12 329.25 Td (om ) Tj ET Q q 0 0 0 rg BT 243.59 329.25 Td (head-to-head ) Tj ET Q q 0 0 0 rg BT 300.15 329.25 Td (studies, ) Tj ET Q q 0 0 0 rg BT 333.67 329.25 Td (could ) Tj ET Q q 0 0 0 rg BT 359.13 329.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 384.59 329.25 Td (a ) Tj ET Q q 0 0 0 rg BT 392.83 329.25 Td (pr) Tj ET Q q 0 0 0 rg BT 401.35 329.25 Td (oduct’) Tj ET Q q 0 0 0 rg BT 425.61 329.25 Td (s ) Tj ET Q q 0 0 0 rg BT 432.75 329.25 Td (formulary ) Tj ET Q q 0 0 0 rg BT 475.99 329.25 Td (listing, ) Tj ET Q q 0 0 0 rg BT 506.74 329.25 Td (which ) Tj ET Q q 0 0 0 rg BT 533.87 329.25 Td (could ) Tj ET Q q 0 0 0 rg BT 559.33 329.25 Td (also ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 317.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 76.82 317.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 101.53 317.25 Td (r) Tj ET Q q 0 0 0 rg BT 105.05 317.25 Td (evenues.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 293.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.33 293.25 Td (illegal ) Tj ET Q q 0 0 0 rg BT 82.10 293.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 132.12 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 149.90 293.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 168.23 293.25 Td (by ) Tj ET Q q 0 0 0 rg BT 179.89 293.25 Td (third ) Tj ET Q q 0 0 0 rg BT 202.12 293.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 232.12 293.25 Td (of ) Tj ET Q q 0 0 0 rg BT 242.67 293.25 Td (counterfeit ) Tj ET Q q 0 0 0 rg BT 289.89 293.25 Td (or ) Tj ET Q q 0 0 0 rg BT 301.00 293.25 Td (unregistered ) Tj ET Q q 0 0 0 rg BT 354.89 293.25 Td (versions ) Tj ET Q q 0 0 0 rg BT 391.00 293.25 Td (of ) Tj ET Q q 0 0 0 rg BT 401.55 293.25 Td (our ) Tj ET Q q 0 0 0 rg BT 418.23 293.25 Td (products ) Tj ET Q q 0 0 0 rg BT 456.01 293.25 Td (or ) Tj ET Q q 0 0 0 rg BT 467.12 293.25 Td (stolen ) Tj ET Q q 0 0 0 rg BT 493.79 293.25 Td (products ) Tj ET Q q 0 0 0 rg BT 531.57 293.25 Td (could ) Tj ET Q q 0 0 0 rg BT 556.57 293.25 Td (have ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 281.25 Td (a ) Tj ET Q q 0 0 0 rg BT 43.50 281.25 Td (negative ) Tj ET Q q 0 0 0 rg BT 80.43 281.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 110.71 281.25 Td (on ) Tj ET Q q 0 0 0 rg BT 123.77 281.25 Td (our ) Tj ET Q q 0 0 0 rg BT 140.72 281.25 Td (revenues, ) Tj ET Q q 0 0 0 rg BT 182.38 281.25 Td (earnings, ) Tj ET Q q 0 0 0 rg BT 223.50 281.25 Td (reputation ) Tj ET Q q 0 0 0 rg BT 268.79 281.25 Td (and ) Tj ET Q q 0 0 0 rg BT 286.85 281.25 Td (business. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 269.25 Td (Thir) Tj ET Q q 0 0 0 rg BT 52.86 269.25 Td (d ) Tj ET Q q 0 0 0 rg BT 60.54 269.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 90.99 269.25 Td (may ) Tj ET Q q 0 0 0 rg BT 110.33 269.25 Td (illegally ) Tj ET Q q 0 0 0 rg BT 145.78 269.25 Td (distribute ) Tj ET Q q 0 0 0 rg BT 186.79 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 204.47 269.25 Td (sell ) Tj ET Q q 0 0 0 rg BT 221.03 269.25 Td (counterfeit ) Tj ET Q q 0 0 0 rg BT 267.03 269.25 Td (versions ) Tj ET Q q 0 0 0 rg BT 303.03 269.25 Td (of ) Tj ET Q q 0 0 0 rg BT 313.49 269.25 Td (our ) Tj ET Q q 0 0 0 rg BT 330.06 269.25 Td (pr) Tj ET Q q 0 0 0 rg BT 338.58 269.25 Td (oducts, ) Tj ET Q q 0 0 0 rg BT 369.87 269.25 Td (which ) Tj ET Q q 0 0 0 rg BT 396.43 269.25 Td (do ) Tj ET Q q 0 0 0 rg BT 409.11 269.25 Td (not ) Tj ET Q q 0 0 0 rg BT 424.56 269.25 Td (meet ) Tj ET Q q 0 0 0 rg BT 446.12 269.25 Td (our ) Tj ET Q q 0 0 0 rg BT 462.69 269.25 Td (rigor) Tj ET Q q 0 0 0 rg BT 482.88 269.25 Td (ous ) Tj ET Q q 0 0 0 rg BT 499.44 269.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 561.01 269.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 257.25 Td (testing ) Tj ET Q q 0 0 0 rg BT 64.40 257.25 Td (standar) Tj ET Q q 0 0 0 rg BT 94.59 257.25 Td (ds. ) Tj ET Q q 0 0 0 rg BT 107.58 257.25 Td (A) Tj ET Q q 0 0 0 rg BT 113.51 257.25 Td ( ) Tj ET Q q 0 0 0 rg BT 115.24 257.25 Td (patient ) Tj ET Q q 0 0 0 rg BT 144.74 257.25 Td (who ) Tj ET Q q 0 0 0 rg BT 163.14 257.25 Td (r) Tj ET Q q 0 0 0 rg BT 166.66 257.25 Td (eceives ) Tj ET Q q 0 0 0 rg BT 197.26 257.25 Td (a ) Tj ET Q q 0 0 0 rg BT 203.99 257.25 Td (counterfeit ) Tj ET Q q 0 0 0 rg BT 249.04 257.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 269.66 257.25 Td (may ) Tj ET Q q 0 0 0 rg BT 288.05 257.25 Td (be ) Tj ET Q q 0 0 0 rg BT 299.22 257.25 Td (at ) Tj ET Q q 0 0 0 rg BT 308.72 257.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 325.45 257.25 Td (for ) Tj ET Q q 0 0 0 rg BT 338.85 257.25 Td (a ) Tj ET Q q 0 0 0 rg BT 345.58 257.25 Td (number ) Tj ET Q q 0 0 0 rg BT 377.87 257.25 Td (of ) Tj ET Q q 0 0 0 rg BT 387.37 257.25 Td (danger) Tj ET Q q 0 0 0 rg BT 415.33 257.25 Td (ous ) Tj ET Q q 0 0 0 rg BT 430.95 257.25 Td (health ) Tj ET Q q 0 0 0 rg BT 457.68 257.25 Td (consequences. ) Tj ET Q q 0 0 0 rg BT 516.89 257.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 534.73 257.25 Td (r) Tj ET Q q 0 0 0 rg BT 538.25 257.25 Td (eputation ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 245.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.38 245.25 Td (business ) Tj ET Q q 0 0 0 rg BT 89.66 245.25 Td (could ) Tj ET Q q 0 0 0 rg BT 114.26 245.25 Td (suffer ) Tj ET Q q 0 0 0 rg BT 139.42 245.25 Td (harm ) Tj ET Q q 0 0 0 rg BT 162.91 245.25 Td (as ) Tj ET Q q 0 0 0 rg BT 174.19 245.25 Td (a ) Tj ET Q q 0 0 0 rg BT 181.57 245.25 Td (r) Tj ET Q q 0 0 0 rg BT 185.09 245.25 Td (esult ) Tj ET Q q 0 0 0 rg BT 206.36 245.25 Td (of ) Tj ET Q q 0 0 0 rg BT 216.52 245.25 Td (counterfeit ) Tj ET Q q 0 0 0 rg BT 262.23 245.25 Td (drugs ) Tj ET Q q 0 0 0 rg BT 287.39 245.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 306.44 245.25 Td (under ) Tj ET Q q 0 0 0 rg BT 332.16 245.25 Td (our ) Tj ET Q q 0 0 0 rg BT 348.43 245.25 Td (brand ) Tj ET Q q 0 0 0 rg BT 374.71 245.25 Td (name. ) Tj ET Q q 0 0 0 rg BT 401.25 245.25 Td (Thefts ) Tj ET Q q 0 0 0 rg BT 428.08 245.25 Td (of ) Tj ET Q q 0 0 0 rg BT 438.24 245.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 478.39 245.25 Td (at ) Tj ET Q q 0 0 0 rg BT 488.55 245.25 Td (war) Tj ET Q q 0 0 0 rg BT 503.74 245.25 Td (ehouses, ) Tj ET Q q 0 0 0 rg BT 540.28 245.25 Td (plants ) Tj ET Q q 0 0 0 rg BT 567.11 245.25 Td (or ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 233.25 Td (while ) Tj ET Q q 0 0 0 rg BT 60.55 233.25 Td (in-transit, ) Tj ET Q q 0 0 0 rg BT 103.16 233.25 Td (which ) Tj ET Q q 0 0 0 rg BT 129.93 233.25 Td (ar) Tj ET Q q 0 0 0 rg BT 138.45 233.25 Td (e ) Tj ET Q q 0 0 0 rg BT 145.78 233.25 Td (then ) Tj ET Q q 0 0 0 rg BT 165.88 233.25 Td (not ) Tj ET Q q 0 0 0 rg BT 181.54 233.25 Td (pr) Tj ET Q q 0 0 0 rg BT 190.06 233.25 Td (operly ) Tj ET Q q 0 0 0 rg BT 218.49 233.25 Td (stor) Tj ET Q q 0 0 0 rg BT 233.68 233.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 246.01 233.25 Td (and ) Tj ET Q q 0 0 0 rg BT 263.89 233.25 Td (ar) Tj ET Q q 0 0 0 rg BT 272.41 233.25 Td (e ) Tj ET Q q 0 0 0 rg BT 279.74 233.25 Td (later ) Tj ET Q q 0 0 0 rg BT 301.51 233.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 321.06 233.25 Td (thr) Tj ET Q q 0 0 0 rg BT 332.36 233.25 Td (ough ) Tj ET Q q 0 0 0 rg BT 355.25 233.25 Td (unauthorized ) Tj ET Q q 0 0 0 rg BT 410.91 233.25 Td (channels, ) Tj ET Q q 0 0 0 rg BT 451.84 233.25 Td (could ) Tj ET Q q 0 0 0 rg BT 476.94 233.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 518.14 233.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 548.24 233.25 Td (patient ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 221.25 Td (safety) Tj ET Q q 0 0 0 rg BT 58.77 221.25 Td (, ) Tj ET Q q 0 0 0 rg BT 63.97 221.25 Td (our ) Tj ET Q q 0 0 0 rg BT 80.56 221.25 Td (r) Tj ET Q q 0 0 0 rg BT 84.08 221.25 Td (eputation ) Tj ET Q q 0 0 0 rg BT 124.55 221.25 Td (and ) Tj ET Q q 0 0 0 rg BT 142.25 221.25 Td (our ) Tj ET Q q 0 0 0 rg BT 158.83 221.25 Td (business. ) Tj ET Q q 0 0 0 rg BT 197.92 221.25 Td (In ) Tj ET Q q 0 0 0 rg BT 208.95 221.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 247.48 221.25 Td (diversion ) Tj ET Q q 0 0 0 rg BT 287.40 221.25 Td (of ) Tj ET Q q 0 0 0 rg BT 297.87 221.25 Td (pr) Tj ET Q q 0 0 0 rg BT 306.39 221.25 Td (oducts ) Tj ET Q q 0 0 0 rg BT 335.20 221.25 Td (fr) Tj ET Q q 0 0 0 rg BT 341.49 221.25 Td (om ) Tj ET Q q 0 0 0 rg BT 356.41 221.25 Td (their ) Tj ET Q q 0 0 0 rg BT 378.00 221.25 Td (authorized ) Tj ET Q q 0 0 0 rg BT 423.47 221.25 Td (market ) Tj ET Q q 0 0 0 rg BT 453.94 221.25 Td (into ) Tj ET Q q 0 0 0 rg BT 472.19 221.25 Td (other ) Tj ET Q q 0 0 0 rg BT 496.00 221.25 Td (channels ) Tj ET Q q 0 0 0 rg BT 534.24 221.25 Td (may ) Tj ET Q q 0 0 0 rg BT 553.60 221.25 Td (r) Tj ET Q q 0 0 0 rg BT 557.12 221.25 Td (esult ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 209.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 209.25 Td (r) Tj ET Q q 0 0 0 rg BT 49.80 209.25 Td (educed ) Tj ET Q q 0 0 0 rg BT 80.61 209.25 Td (r) Tj ET Q q 0 0 0 rg BT 84.13 209.25 Td (evenues ) Tj ET Q q 0 0 0 rg BT 118.28 209.25 Td (and ) Tj ET Q q 0 0 0 rg BT 135.78 209.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 179.37 209.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 204.08 209.25 Td (our ) Tj ET Q q 0 0 0 rg BT 220.47 209.25 Td (pr) Tj ET Q q 0 0 0 rg BT 228.99 209.25 Td (ofitability) Tj ET Q q 0 0 0 rg BT 267.33 209.25 Td (.) Tj ET Q endstream endobj 49 0 obj <> endobj 50 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (24) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.15 749.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.74 749.25 Td (are ) Tj ET Q q 0 0 0 rg BT 68.22 749.25 Td (dependent ) Tj ET Q q 0 0 0 rg BT 113.59 749.25 Td (on ) Tj ET Q q 0 0 0 rg BT 127.31 749.25 Td (information ) Tj ET Q q 0 0 0 rg BT 179.92 749.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 228.07 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 246.78 749.25 Td (our ) Tj ET Q q 0 0 0 rg BT 264.39 749.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 298.65 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 317.37 749.25 Td (infrastructure ) Tj ET Q q 0 0 0 rg BT 378.31 749.25 Td (face ) Tj ET Q q 0 0 0 rg BT 398.67 749.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 430.71 749.25 Td (risks, ) Tj ET Q q 0 0 0 rg BT 455.82 749.25 Td (including ) Tj ET Q q 0 0 0 rg BT 498.43 749.25 Td (from ) Tj ET Q q 0 0 0 rg BT 521.58 749.25 Td (cybersecurity ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (breaches ) Tj ET Q q 0 0 0 rg BT 75.16 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 93.22 737.25 Td (data ) Tj ET Q q 0 0 0 rg BT 113.50 737.25 Td (leakage.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 725.25 Td (e ) Tj ET Q q 0 0 0 rg BT 49.56 725.25 Td (r) Tj ET Q q 0 0 0 rg BT 53.08 725.25 Td (ely ) Tj ET Q q 0 0 0 rg BT 66.45 725.25 Td (extensively ) Tj ET Q q 0 0 0 rg BT 112.02 725.25 Td (on ) Tj ET Q q 0 0 0 rg BT 123.73 725.25 Td (IT) Tj ET Q q 0 0 0 rg BT 132.44 725.25 Td ( ) Tj ET Q q 0 0 0 rg BT 134.15 725.25 Td (systems, ) Tj ET Q q 0 0 0 rg BT 168.91 725.25 Td (networks ) Tj ET Q q 0 0 0 rg BT 206.73 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 223.44 725.25 Td (services, ) Tj ET Q q 0 0 0 rg BT 259.86 725.25 Td (including ) Tj ET Q q 0 0 0 rg BT 299.34 725.25 Td (internet ) Tj ET Q q 0 0 0 rg BT 332.15 725.25 Td (sites, ) Tj ET Q q 0 0 0 rg BT 354.14 725.25 Td (data ) Tj ET Q q 0 0 0 rg BT 373.63 725.25 Td (hosting ) Tj ET Q q 0 0 0 rg BT 404.79 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 421.50 725.25 Td (pr) Tj ET Q q 0 0 0 rg BT 430.02 725.25 Td (ocessing ) Tj ET Q q 0 0 0 rg BT 466.17 725.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 502.32 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 519.03 725.25 Td (tools, ) Tj ET Q q 0 0 0 rg BT 542.69 725.25 Td (physical ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (security ) Tj ET Q q 0 0 0 rg BT 70.27 713.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 103.43 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 121.04 713.25 Td (other ) Tj ET Q q 0 0 0 rg BT 144.76 713.25 Td (har) Tj ET Q q 0 0 0 rg BT 158.29 713.25 Td (dwar) Tj ET Q q 0 0 0 rg BT 178.48 713.25 Td (e, ) Tj ET Q q 0 0 0 rg BT 188.03 713.25 Td (softwar) Tj ET Q q 0 0 0 rg BT 217.67 713.25 Td (e ) Tj ET Q q 0 0 0 rg BT 224.72 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 242.33 713.25 Td (technical ) Tj ET Q q 0 0 0 rg BT 281.59 713.25 Td (applications ) Tj ET Q q 0 0 0 rg BT 333.65 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 351.26 713.25 Td (platforms, ) Tj ET Q q 0 0 0 rg BT 394.71 713.25 Td (some ) Tj ET Q q 0 0 0 rg BT 417.88 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 428.27 713.25 Td (which ) Tj ET Q q 0 0 0 rg BT 454.76 713.25 Td (ar) Tj ET Q q 0 0 0 rg BT 463.29 713.25 Td (e ) Tj ET Q q 0 0 0 rg BT 470.34 713.25 Td (managed, ) Tj ET Q q 0 0 0 rg BT 512.11 713.25 Td (hosted ) Tj ET Q q 0 0 0 rg BT 540.83 713.25 Td (pr) Tj ET Q q 0 0 0 rg BT 549.35 713.25 Td (ovided ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 66.35 701.25 Td (used ) Tj ET Q q 0 0 0 rg BT 88.36 701.25 Td (for ) Tj ET Q q 0 0 0 rg BT 103.71 701.25 Td (thir) Tj ET Q q 0 0 0 rg BT 117.79 701.25 Td (d-parties ) Tj ET Q q 0 0 0 rg BT 157.58 701.25 Td (or ) Tj ET Q q 0 0 0 rg BT 170.16 701.25 Td (their ) Tj ET Q q 0 0 0 rg BT 192.72 701.25 Td (vendors, ) Tj ET Q q 0 0 0 rg BT 230.57 701.25 Td (to ) Tj ET Q q 0 0 0 rg BT 242.03 701.25 Td (assist ) Tj ET Q q 0 0 0 rg BT 267.94 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 279.40 701.25 Td (conducting ) Tj ET Q q 0 0 0 rg BT 327.51 701.25 Td (our ) Tj ET Q q 0 0 0 rg BT 345.09 701.25 Td (business. ) Tj ET Q q 0 0 0 rg BT 384.89 701.25 Td (A) Tj ET Q q 0 0 0 rg BT 390.82 701.25 Td ( ) Tj ET Q q 0 0 0 rg BT 394.50 701.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 440.41 701.25 Td (br) Tj ET Q q 0 0 0 rg BT 448.93 701.25 Td (eakdown, ) Tj ET Q q 0 0 0 rg BT 490.66 701.25 Td (invasion, ) Tj ET Q q 0 0 0 rg BT 530.72 701.25 Td (corruption, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (destruction ) Tj ET Q q 0 0 0 rg BT 83.23 689.25 Td (or ) Tj ET Q q 0 0 0 rg BT 94.36 689.25 Td (interruption ) Tj ET Q q 0 0 0 rg BT 144.93 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 154.95 689.25 Td (critical ) Tj ET Q q 0 0 0 rg BT 186.06 689.25 Td (information ) Tj ET Q q 0 0 0 rg BT 235.53 689.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 281.63 689.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 314.42 689.25 Td (or ) Tj ET Q q 0 0 0 rg BT 325.55 689.25 Td (infrastructur) Tj ET Q q 0 0 0 rg BT 376.30 689.25 Td (e, ) Tj ET Q q 0 0 0 rg BT 385.47 689.25 Td (by ) Tj ET Q q 0 0 0 rg BT 397.15 689.25 Td (our ) Tj ET Q q 0 0 0 rg BT 413.28 689.25 Td (workfor) Tj ET Q q 0 0 0 rg BT 444.57 689.25 Td (ce, ) Tj ET Q q 0 0 0 rg BT 458.19 689.25 Td (others ) Tj ET Q q 0 0 0 rg BT 485.42 689.25 Td (with ) Tj ET Q q 0 0 0 rg BT 504.89 689.25 Td (authorized ) Tj ET Q q 0 0 0 rg BT 549.90 689.25 Td (access ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (to ) Tj ET Q q 0 0 0 rg BT 45.26 677.25 Td (our ) Tj ET Q q 0 0 0 rg BT 60.62 677.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 92.65 677.25 Td (or ) Tj ET Q q 0 0 0 rg BT 103.02 677.25 Td (unauthorized ) Tj ET Q q 0 0 0 rg BT 157.28 677.25 Td (persons ) Tj ET Q q 0 0 0 rg BT 189.87 677.25 Td (could ) Tj ET Q q 0 0 0 rg BT 213.56 677.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 256.13 677.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 284.82 677.25 Td (operations. ) Tj ET Q q 0 0 0 rg BT 331.58 677.25 Td (The ) Tj ET Q q 0 0 0 rg BT 348.05 677.25 Td (ever) Tj ET Q q 0 0 0 rg BT 365.06 677.25 Td (-incr) Tj ET Q q 0 0 0 rg BT 384.13 677.25 Td (easing ) Tj ET Q q 0 0 0 rg BT 411.71 677.25 Td (use ) Tj ET Q q 0 0 0 rg BT 426.52 677.25 Td (and ) Tj ET Q q 0 0 0 rg BT 443.00 677.25 Td (evolution ) Tj ET Q q 0 0 0 rg BT 481.69 677.25 Td (of ) Tj ET Q q 0 0 0 rg BT 490.94 677.25 Td (technology) Tj ET Q q 0 0 0 rg BT 534.26 677.25 Td (, ) Tj ET Q q 0 0 0 rg BT 538.24 677.25 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (cloud-based ) Tj ET Q q 0 0 0 rg BT 87.32 665.25 Td (computing, ) Tj ET Q q 0 0 0 rg BT 134.49 665.25 Td (cr) Tj ET Q q 0 0 0 rg BT 142.45 665.25 Td (eates ) Tj ET Q q 0 0 0 rg BT 165.44 665.25 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 221.22 665.25 Td (for ) Tj ET Q q 0 0 0 rg BT 235.34 665.25 Td (the ) Tj ET Q q 0 0 0 rg BT 250.00 665.25 Td (unintentional ) Tj ET Q q 0 0 0 rg BT 305.78 665.25 Td (dissemination ) Tj ET Q q 0 0 0 rg BT 363.78 665.25 Td (or ) Tj ET Q q 0 0 0 rg BT 375.12 665.25 Td (intentional ) Tj ET Q q 0 0 0 rg BT 420.89 665.25 Td (destruction ) Tj ET Q q 0 0 0 rg BT 468.33 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 478.56 665.25 Td (confidential ) Tj ET Q q 0 0 0 rg BT 528.77 665.25 Td (information ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (stor) Tj ET Q q 0 0 0 rg BT 51.19 653.25 Td (ed ) Tj ET Q q 0 0 0 rg BT 62.60 653.25 Td (in ) Tj ET Q q 0 0 0 rg BT 72.35 653.25 Td (our) Tj ET Q q 0 0 0 rg BT 85.13 653.25 Td (, ) Tj ET Q q 0 0 0 rg BT 89.61 653.25 Td (or ) Tj ET Q q 0 0 0 rg BT 100.47 653.25 Td (our ) Tj ET Q q 0 0 0 rg BT 116.33 653.25 Td (thir) Tj ET Q q 0 0 0 rg BT 130.41 653.25 Td (d-party ) Tj ET Q q 0 0 0 rg BT 161.82 653.25 Td (pr) Tj ET Q q 0 0 0 rg BT 170.34 653.25 Td (oviders', ) Tj ET Q q 0 0 0 rg BT 206.39 653.25 Td (systems, ) Tj ET Q q 0 0 0 rg BT 241.41 653.25 Td (portable ) Tj ET Q q 0 0 0 rg BT 277.27 653.25 Td (media ) Tj ET Q q 0 0 0 rg BT 303.68 653.25 Td (or ) Tj ET Q q 0 0 0 rg BT 314.54 653.25 Td (storage ) Tj ET Q q 0 0 0 rg BT 346.52 653.25 Td (devices. ) Tj ET Q q 0 0 0 rg BT 380.41 653.25 Td (W) Tj ET Q q 0 0 0 rg BT 387.82 653.25 Td (e ) Tj ET Q q 0 0 0 rg BT 394.23 653.25 Td (could ) Tj ET Q q 0 0 0 rg BT 418.42 653.25 Td (also ) Tj ET Q q 0 0 0 rg BT 437.06 653.25 Td (experience ) Tj ET Q q 0 0 0 rg BT 482.34 653.25 Td (a ) Tj ET Q q 0 0 0 rg BT 489.31 653.25 Td (business ) Tj ET Q q 0 0 0 rg BT 525.17 653.25 Td (interruption, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (theft ) Tj ET Q q 0 0 0 rg BT 56.26 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 66.52 641.25 Td (confidential ) Tj ET Q q 0 0 0 rg BT 116.77 641.25 Td (information ) Tj ET Q q 0 0 0 rg BT 166.47 641.25 Td (or ) Tj ET Q q 0 0 0 rg BT 177.85 641.25 Td (r) Tj ET Q q 0 0 0 rg BT 181.37 641.25 Td (eputational ) Tj ET Q q 0 0 0 rg BT 229.40 641.25 Td (damage ) Tj ET Q q 0 0 0 rg BT 263.54 641.25 Td (fr) Tj ET Q q 0 0 0 rg BT 269.84 641.25 Td (om ) Tj ET Q q 0 0 0 rg BT 284.55 641.25 Td (industrial ) Tj ET Q q 0 0 0 rg BT 325.93 641.25 Td (espionage ) Tj ET Q q 0 0 0 rg BT 368.95 641.25 Td (attacks, ) Tj ET Q q 0 0 0 rg BT 402.26 641.25 Td (malwar) Tj ET Q q 0 0 0 rg BT 432.45 641.25 Td (e ) Tj ET Q q 0 0 0 rg BT 439.37 641.25 Td (or ) Tj ET Q q 0 0 0 rg BT 450.75 641.25 Td (other ) Tj ET Q q 0 0 0 rg BT 474.34 641.25 Td (cyber) Tj ET Q q 0 0 0 rg BT 496.34 641.25 Td (-attacks, ) Tj ET Q q 0 0 0 rg BT 532.98 641.25 Td (which ) Tj ET Q q 0 0 0 rg BT 559.35 641.25 Td (may ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (compr) Tj ET Q q 0 0 0 rg BT 61.18 629.25 Td (omise ) Tj ET Q q 0 0 0 rg BT 87.00 629.25 Td (our ) Tj ET Q q 0 0 0 rg BT 103.39 629.25 Td (system ) Tj ET Q q 0 0 0 rg BT 132.54 629.25 Td (infrastructur) Tj ET Q q 0 0 0 rg BT 183.29 629.25 Td (e ) Tj ET Q q 0 0 0 rg BT 190.22 629.25 Td (or ) Tj ET Q q 0 0 0 rg BT 201.60 629.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 221.31 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 231.58 629.25 Td (data ) Tj ET Q q 0 0 0 rg BT 251.85 629.25 Td (leakage, ) Tj ET Q q 0 0 0 rg BT 287.94 629.25 Td (either ) Tj ET Q q 0 0 0 rg BT 313.76 629.25 Td (internally ) Tj ET Q q 0 0 0 rg BT 355.13 629.25 Td (or ) Tj ET Q q 0 0 0 rg BT 366.52 629.25 Td (at ) Tj ET Q q 0 0 0 rg BT 376.79 629.25 Td (our ) Tj ET Q q 0 0 0 rg BT 393.17 629.25 Td (thir) Tj ET Q q 0 0 0 rg BT 407.25 629.25 Td (d-party ) Tj ET Q q 0 0 0 rg BT 439.18 629.25 Td (pr) Tj ET Q q 0 0 0 rg BT 447.70 629.25 Td (oviders. ) Tj ET Q q 0 0 0 rg BT 481.95 629.25 Td (Although ) Tj ET Q q 0 0 0 rg BT 521.11 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 535.82 629.25 Td (aggr) Tj ET Q q 0 0 0 rg BT 554.34 629.25 Td (egate ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 66.28 617.25 Td (on ) Tj ET Q q 0 0 0 rg BT 79.35 617.25 Td (our ) Tj ET Q q 0 0 0 rg BT 96.31 617.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 142.16 617.25 Td (and ) Tj ET Q q 0 0 0 rg BT 160.23 617.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 198.85 617.25 Td (condition ) Tj ET Q q 0 0 0 rg BT 239.69 617.25 Td (has ) Tj ET Q q 0 0 0 rg BT 256.65 617.25 Td (not ) Tj ET Q q 0 0 0 rg BT 272.49 617.25 Td (been ) Tj ET Q q 0 0 0 rg BT 294.44 617.25 Td (material ) Tj ET Q q 0 0 0 rg BT 331.39 617.25 Td (to ) Tj ET Q q 0 0 0 rg BT 342.24 617.25 Td (date, ) Tj ET Q q 0 0 0 rg BT 365.02 617.25 Td (we ) Tj ET Q q 0 0 0 rg BT 379.20 617.25 Td (have ) Tj ET Q q 0 0 0 rg BT 401.14 617.25 Td (been ) Tj ET Q q 0 0 0 rg BT 423.09 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 438.37 617.25 Td (tar) Tj ET Q q 0 0 0 rg BT 449.67 617.25 Td (get ) Tj ET Q q 0 0 0 rg BT 464.96 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 475.80 617.25 Td (events ) Tj ET Q q 0 0 0 rg BT 503.86 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 514.70 617.25 Td (this ) Tj ET Q q 0 0 0 rg BT 532.22 617.25 Td (natur) Tj ET Q q 0 0 0 rg BT 553.52 617.25 Td (e ) Tj ET Q q 0 0 0 rg BT 561.02 617.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (expect ) Tj ET Q q 0 0 0 rg BT 63.22 605.25 Td (them ) Tj ET Q q 0 0 0 rg BT 84.35 605.25 Td (to ) Tj ET Q q 0 0 0 rg BT 93.81 605.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 129.94 605.25 Td (as ) Tj ET Q q 0 0 0 rg BT 140.52 605.25 Td (cybersecurity ) Tj ET Q q 0 0 0 rg BT 196.07 605.25 Td (thr) Tj ET Q q 0 0 0 rg BT 207.37 605.25 Td (eats ) Tj ET Q q 0 0 0 rg BT 225.16 605.25 Td (have ) Tj ET Q q 0 0 0 rg BT 245.73 605.25 Td (been ) Tj ET Q q 0 0 0 rg BT 266.29 605.25 Td (rapidly ) Tj ET Q q 0 0 0 rg BT 296.87 605.25 Td (evolving ) Tj ET Q q 0 0 0 rg BT 332.43 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 341.90 605.25 Td (sophistication ) Tj ET Q q 0 0 0 rg BT 399.70 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 416.39 605.25 Td (becoming ) Tj ET Q q 0 0 0 rg BT 456.95 605.25 Td (mor) Tj ET Q q 0 0 0 rg BT 472.69 605.25 Td (e ) Tj ET Q q 0 0 0 rg BT 478.82 605.25 Td (pr) Tj ET Q q 0 0 0 rg BT 487.34 605.25 Td (evalent ) Tj ET Q q 0 0 0 rg BT 517.90 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 527.37 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 541.27 605.25 Td (industry) Tj ET Q q 0 0 0 rg BT 573.50 605.25 Td (. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 593.25 Td (e ) Tj ET Q q 0 0 0 rg BT 50.39 593.25 Td (have ) Tj ET Q q 0 0 0 rg BT 71.81 593.25 Td (invested ) Tj ET Q q 0 0 0 rg BT 107.12 593.25 Td (in ) Tj ET Q q 0 0 0 rg BT 117.44 593.25 Td (industry ) Tj ET Q q 0 0 0 rg BT 152.76 593.25 Td (appr) Tj ET Q q 0 0 0 rg BT 171.28 593.25 Td (opriate ) Tj ET Q q 0 0 0 rg BT 202.71 593.25 Td (pr) Tj ET Q q 0 0 0 rg BT 211.23 593.25 Td (otections ) Tj ET Q q 0 0 0 rg BT 249.88 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 267.42 593.25 Td (monitoring ) Tj ET Q q 0 0 0 rg BT 314.41 593.25 Td (practices ) Tj ET Q q 0 0 0 rg BT 353.61 593.25 Td (of ) Tj ET Q q 0 0 0 rg BT 363.93 593.25 Td (our ) Tj ET Q q 0 0 0 rg BT 380.37 593.25 Td (data ) Tj ET Q q 0 0 0 rg BT 400.69 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 418.23 593.25 Td (IT) Tj ET Q q 0 0 0 rg BT 426.94 593.25 Td ( ) Tj ET Q q 0 0 0 rg BT 429.49 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 439.81 593.25 Td (r) Tj ET Q q 0 0 0 rg BT 443.33 593.25 Td (educe ) Tj ET Q q 0 0 0 rg BT 469.19 593.25 Td (these ) Tj ET Q q 0 0 0 rg BT 492.28 593.25 Td (risks ) Tj ET Q q 0 0 0 rg BT 513.71 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 531.25 593.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 568.23 593.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (monitor ) Tj ET Q q 0 0 0 rg BT 69.85 581.25 Td (our ) Tj ET Q q 0 0 0 rg BT 85.93 581.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 118.66 581.25 Td (on ) Tj ET Q q 0 0 0 rg BT 130.84 581.25 Td (an ) Tj ET Q q 0 0 0 rg BT 143.03 581.25 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 177.99 581.25 Td (basis ) Tj ET Q q 0 0 0 rg BT 200.73 581.25 Td (for ) Tj ET Q q 0 0 0 rg BT 214.58 581.25 Td (any ) Tj ET Q q 0 0 0 rg BT 231.21 581.25 Td (curr) Tj ET Q q 0 0 0 rg BT 248.06 581.25 Td (ent ) Tj ET Q q 0 0 0 rg BT 262.46 581.25 Td (or ) Tj ET Q q 0 0 0 rg BT 273.53 581.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 311.26 581.25 Td (thr) Tj ET Q q 0 0 0 rg BT 322.56 581.25 Td (eats. ) Tj ET Q q 0 0 0 rg BT 343.35 581.25 Td (W) Tj ET Q q 0 0 0 rg BT 350.77 581.25 Td (e ) Tj ET Q q 0 0 0 rg BT 357.39 581.25 Td (maintain ) Tj ET Q q 0 0 0 rg BT 395.13 581.25 Td (cyber ) Tj ET Q q 0 0 0 rg BT 419.52 581.25 Td (insurance, ) Tj ET Q q 0 0 0 rg BT 463.64 581.25 Td (however) Tj ET Q q 0 0 0 rg BT 496.41 581.25 Td (, ) Tj ET Q q 0 0 0 rg BT 501.09 581.25 Td (this ) Tj ET Q q 0 0 0 rg BT 517.72 581.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 559.34 581.25 Td (may ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (not ) Tj ET Q q 0 0 0 rg BT 50.60 569.25 Td (be ) Tj ET Q q 0 0 0 rg BT 61.87 569.25 Td (sufficient ) Tj ET Q q 0 0 0 rg BT 100.35 569.25 Td (to ) Tj ET Q q 0 0 0 rg BT 109.96 569.25 Td (cover ) Tj ET Q q 0 0 0 rg BT 133.99 569.25 Td (the ) Tj ET Q q 0 0 0 rg BT 148.03 569.25 Td (financial, ) Tj ET Q q 0 0 0 rg BT 187.91 569.25 Td (legal, ) Tj ET Q q 0 0 0 rg BT 212.23 569.25 Td (business ) Tj ET Q q 0 0 0 rg BT 247.94 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 258.66 569.25 Td (r) Tj ET Q q 0 0 0 rg BT 262.18 569.25 Td (eputational ) Tj ET Q q 0 0 0 rg BT 309.56 569.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 335.28 569.25 Td (that ) Tj ET Q q 0 0 0 rg BT 352.66 569.25 Td (may ) Tj ET Q q 0 0 0 rg BT 371.14 569.25 Td (r) Tj ET Q q 0 0 0 rg BT 374.66 569.25 Td (esult ) Tj ET Q q 0 0 0 rg BT 395.38 569.25 Td (fr) Tj ET Q q 0 0 0 rg BT 401.67 569.25 Td (om ) Tj ET Q q 0 0 0 rg BT 415.72 569.25 Td (an ) Tj ET Q q 0 0 0 rg BT 427.55 569.25 Td (interruption ) Tj ET Q q 0 0 0 rg BT 477.71 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 488.42 569.25 Td (br) Tj ET Q q 0 0 0 rg BT 496.94 569.25 Td (each ) Tj ET Q q 0 0 0 rg BT 517.65 569.25 Td (of ) Tj ET Q q 0 0 0 rg BT 527.25 569.25 Td (our ) Tj ET Q q 0 0 0 rg BT 542.97 569.25 Td (systems. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (Ther) Tj ET Q q 0 0 0 rg BT 54.52 557.25 Td (e ) Tj ET Q q 0 0 0 rg BT 60.93 557.25 Td (can ) Tj ET Q q 0 0 0 rg BT 77.35 557.25 Td (be ) Tj ET Q q 0 0 0 rg BT 88.76 557.25 Td (no ) Tj ET Q q 0 0 0 rg BT 100.74 557.25 Td (assurance ) Tj ET Q q 0 0 0 rg BT 143.26 557.25 Td (that ) Tj ET Q q 0 0 0 rg BT 160.79 557.25 Td (our ) Tj ET Q q 0 0 0 rg BT 176.66 557.25 Td (continuing ) Tj ET Q q 0 0 0 rg BT 221.41 557.25 Td (efforts ) Tj ET Q q 0 0 0 rg BT 248.94 557.25 Td (will ) Tj ET Q q 0 0 0 rg BT 265.92 557.25 Td (pr) Tj ET Q q 0 0 0 rg BT 274.44 557.25 Td (event ) Tj ET Q q 0 0 0 rg BT 297.51 557.25 Td (br) Tj ET Q q 0 0 0 rg BT 306.03 557.25 Td (eakdowns ) Tj ET Q q 0 0 0 rg BT 347.45 557.25 Td (or ) Tj ET Q q 0 0 0 rg BT 358.31 557.25 Td (br) Tj ET Q q 0 0 0 rg BT 366.83 557.25 Td (eaches ) Tj ET Q q 0 0 0 rg BT 396.01 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 405.77 557.25 Td (our ) Tj ET Q q 0 0 0 rg BT 421.63 557.25 Td (or ) Tj ET Q q 0 0 0 rg BT 432.50 557.25 Td (our ) Tj ET Q q 0 0 0 rg BT 448.37 557.25 Td (thir) Tj ET Q q 0 0 0 rg BT 462.45 557.25 Td (d-party ) Tj ET Q q 0 0 0 rg BT 493.86 557.25 Td (pr) Tj ET Q q 0 0 0 rg BT 502.38 557.25 Td (oviders’) Tj ET Q q 0 0 0 rg BT 534.04 557.25 Td ( ) Tj ET Q q 0 0 0 rg BT 536.01 557.25 Td (databases ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (or ) Tj ET Q q 0 0 0 rg BT 47.39 545.25 Td (systems ) Tj ET Q q 0 0 0 rg BT 80.44 545.25 Td (that ) Tj ET Q q 0 0 0 rg BT 98.50 545.25 Td (could ) Tj ET Q q 0 0 0 rg BT 123.22 545.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 164.03 545.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 188.74 545.25 Td (our ) Tj ET Q q 0 0 0 rg BT 205.14 545.25 Td (business.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (Adverse ) Tj ET Q q 0 0 0 rg BT 71.27 521.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 107.66 521.25 Td (in ) Tj ET Q q 0 0 0 rg BT 118.50 521.25 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 141.28 521.25 Td (global, ) Tj ET Q q 0 0 0 rg BT 171.84 521.25 Td (regional, ) Tj ET Q q 0 0 0 rg BT 211.29 521.25 Td (local ) Tj ET Q q 0 0 0 rg BT 233.78 521.25 Td (economic ) Tj ET Q q 0 0 0 rg BT 275.72 521.25 Td (and ) Tj ET Q q 0 0 0 rg BT 293.78 521.25 Td (political ) Tj ET Q q 0 0 0 rg BT 329.61 521.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 374.90 521.25 Td (could ) Tj ET Q q 0 0 0 rg BT 400.17 521.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 440.99 521.25 Td (af) Tj ET Q q 0 0 0 rg BT 449.14 521.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 466.63 521.25 Td (our ) Tj ET Q q 0 0 0 rg BT 483.58 521.25 Td (profitability) Tj ET Q q 0 0 0 rg BT 531.54 521.25 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (Global ) Tj ET Q q 0 0 0 rg BT 66.11 509.25 Td (economic ) Tj ET Q q 0 0 0 rg BT 106.75 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 124.08 509.25 Td (political ) Tj ET Q q 0 0 0 rg BT 159.74 509.25 Td (risks ) Tj ET Q q 0 0 0 rg BT 180.96 509.25 Td (pose ) Tj ET Q q 0 0 0 rg BT 201.61 509.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 246.16 509.25 Td (challenges ) Tj ET Q q 0 0 0 rg BT 291.26 509.25 Td (to ) Tj ET Q q 0 0 0 rg BT 301.36 509.25 Td (a ) Tj ET Q q 0 0 0 rg BT 308.69 509.25 Td (company’) Tj ET Q q 0 0 0 rg BT 346.83 509.25 Td (s ) Tj ET Q q 0 0 0 rg BT 353.05 509.25 Td (gr) Tj ET Q q 0 0 0 rg BT 361.57 509.25 Td (owth ) Tj ET Q q 0 0 0 rg BT 383.35 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 400.67 509.25 Td (pr) Tj ET Q q 0 0 0 rg BT 409.20 509.25 Td (ofitability ) Tj ET Q q 0 0 0 rg BT 450.41 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 467.74 509.25 Td (ar) Tj ET Q q 0 0 0 rg BT 476.26 509.25 Td (e ) Tj ET Q q 0 0 0 rg BT 483.03 509.25 Td (difficult ) Tj ET Q q 0 0 0 rg BT 516.46 509.25 Td (to ) Tj ET Q q 0 0 0 rg BT 526.57 509.25 Td (mitigate. ) Tj ET Q q 0 0 0 rg BT 564.17 509.25 Td (W) Tj ET Q q 0 0 0 rg BT 571.58 509.25 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (generated ) Tj ET Q q 0 0 0 rg BT 78.27 497.25 Td (appr) Tj ET Q q 0 0 0 rg BT 96.79 497.25 Td (oximately ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 137.96 497.25 Td (45%) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 156.29 497.25 Td ( ) Tj ET Q q 0 0 0 rg BT 158.58 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 168.64 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 184.82 497.25 Td (r) Tj ET Q q 0 0 0 rg BT 188.34 497.25 Td (evenues ) Tj ET Q q 0 0 0 rg BT 222.28 497.25 Td (outside ) Tj ET Q q 0 0 0 rg BT 253.45 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 263.52 497.25 Td (the ) Tj ET Q q 0 0 0 rg BT 278.03 497.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 297.54 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 307.61 497.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 332.23 497.25 Td (As ) Tj ET Q q 0 0 0 rg BT 344.52 497.25 Td (such, ) Tj ET Q q 0 0 0 rg BT 367.64 497.25 Td (our ) Tj ET Q q 0 0 0 rg BT 383.82 497.25 Td (r) Tj ET Q q 0 0 0 rg BT 387.34 497.25 Td (evenues, ) Tj ET Q q 0 0 0 rg BT 423.77 497.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 461.06 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 478.35 497.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 498.97 497.25 Td (flow ) Tj ET Q q 0 0 0 rg BT 518.49 497.25 Td (ar) Tj ET Q q 0 0 0 rg BT 527.01 497.25 Td (e ) Tj ET Q q 0 0 0 rg BT 533.73 497.25 Td (exposed ) Tj ET Q q 0 0 0 rg BT 568.23 497.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 53.49 485.25 Td (fr) Tj ET Q q 0 0 0 rg BT 59.78 485.25 Td (om ) Tj ET Q q 0 0 0 rg BT 74.49 485.25 Td (a ) Tj ET Q q 0 0 0 rg BT 81.98 485.25 Td (str) Tj ET Q q 0 0 0 rg BT 92.17 485.25 Td (engthening ) Tj ET Q q 0 0 0 rg BT 139.09 485.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 158.79 485.25 Td (dollar) Tj ET Q q 0 0 0 rg BT 182.13 485.25 Td (. ) Tj ET Q q 0 0 0 rg BT 187.12 485.25 Td (W) Tj ET Q q 0 0 0 rg BT 194.53 485.25 Td (e ) Tj ET Q q 0 0 0 rg BT 201.45 485.25 Td (have ) Tj ET Q q 0 0 0 rg BT 222.82 485.25 Td (exposur) Tj ET Q q 0 0 0 rg BT 254.11 485.25 Td (e ) Tj ET Q q 0 0 0 rg BT 261.03 485.25 Td (to ) Tj ET Q q 0 0 0 rg BT 271.29 485.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 310.44 485.25 Td (cr) Tj ET Q q 0 0 0 rg BT 318.40 485.25 Td (edit ) Tj ET Q q 0 0 0 rg BT 335.88 485.25 Td (risks ) Tj ET Q q 0 0 0 rg BT 357.25 485.25 Td (in ) Tj ET Q q 0 0 0 rg BT 367.52 485.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 382.15 485.25 Td (ope, ) Tj ET Q q 0 0 0 rg BT 401.57 485.25 Td (South ) Tj ET Q q 0 0 0 rg BT 426.66 485.25 Td (America ) Tj ET Q q 0 0 0 rg BT 463.02 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 480.50 485.25 Td (other ) Tj ET Q q 0 0 0 rg BT 504.10 485.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 538.24 485.25 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (fr) Tj ET Q q 0 0 0 rg BT 42.30 473.25 Td (om ) Tj ET Q q 0 0 0 rg BT 57.15 473.25 Td (government-guaranteed ) Tj ET Q q 0 0 0 rg BT 155.86 473.25 Td (hospital ) Tj ET Q q 0 0 0 rg BT 190.72 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 194.24 473.25 Td (eceivables ) Tj ET Q q 0 0 0 rg BT 238.51 473.25 Td (in ) Tj ET Q q 0 0 0 rg BT 248.92 473.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 283.21 473.25 Td (wher) Tj ET Q q 0 0 0 rg BT 302.84 473.25 Td (e ) Tj ET Q q 0 0 0 rg BT 309.90 473.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 350.30 473.25 Td (ar) Tj ET Q q 0 0 0 rg BT 358.82 473.25 Td (e ) Tj ET Q q 0 0 0 rg BT 365.89 473.25 Td (not ) Tj ET Q q 0 0 0 rg BT 381.30 473.25 Td (r) Tj ET Q q 0 0 0 rg BT 384.82 473.25 Td (eceived ) Tj ET Q q 0 0 0 rg BT 417.42 473.25 Td (on ) Tj ET Q q 0 0 0 rg BT 430.05 473.25 Td (time. ) Tj ET Q q 0 0 0 rg BT 452.39 473.25 Td (W) Tj ET Q q 0 0 0 rg BT 459.81 473.25 Td (e ) Tj ET Q q 0 0 0 rg BT 466.87 473.25 Td (have ) Tj ET Q q 0 0 0 rg BT 488.38 473.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 533.23 473.25 Td (operations ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.94 461.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 61.57 461.25 Td (ope, ) Tj ET Q q 0 0 0 rg BT 81.67 461.25 Td (including ) Tj ET Q q 0 0 0 rg BT 122.60 461.25 Td (for ) Tj ET Q q 0 0 0 rg BT 137.44 461.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 199.48 461.25 Td (and ) Tj ET Q q 0 0 0 rg BT 217.65 461.25 Td (distribution. ) Tj ET Q q 0 0 0 rg BT 269.98 461.25 Td (The ) Tj ET Q q 0 0 0 rg BT 288.14 461.25 Td (r) Tj ET Q q 0 0 0 rg BT 291.66 461.25 Td (esults ) Tj ET Q q 0 0 0 rg BT 317.60 461.25 Td (of ) Tj ET Q q 0 0 0 rg BT 328.54 461.25 Td (our ) Tj ET Q q 0 0 0 rg BT 345.60 461.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 391.54 461.25 Td (could ) Tj ET Q q 0 0 0 rg BT 416.92 461.25 Td (be ) Tj ET Q q 0 0 0 rg BT 429.52 461.25 Td (negatively ) Tj ET Q q 0 0 0 rg BT 473.77 461.25 Td (impacted ) Tj ET Q q 0 0 0 rg BT 513.58 461.25 Td (by ) Tj ET Q q 0 0 0 rg BT 526.18 461.25 Td (any ) Tj ET Q q 0 0 0 rg BT 543.78 461.25 Td (member ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (country ) Tj ET Q q 0 0 0 rg BT 69.05 449.25 Td (exiting ) Tj ET Q q 0 0 0 rg BT 98.77 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 113.49 449.25 Td (eur) Tj ET Q q 0 0 0 rg BT 126.45 449.25 Td (ozone ) Tj ET Q q 0 0 0 rg BT 152.28 449.25 Td (monetary ) Tj ET Q q 0 0 0 rg BT 192.55 449.25 Td (union ) Tj ET Q q 0 0 0 rg BT 217.83 449.25 Td (or ) Tj ET Q q 0 0 0 rg BT 229.23 449.25 Td (EU, ) Tj ET Q q 0 0 0 rg BT 247.56 449.25 Td (including ) Tj ET Q q 0 0 0 rg BT 287.84 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 302.56 449.25 Td (planned ) Tj ET Q q 0 0 0 rg BT 337.28 449.25 Td (exit ) Tj ET Q q 0 0 0 rg BT 354.22 449.25 Td (of ) Tj ET Q q 0 0 0 rg BT 364.50 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 379.22 449.25 Td (UK ) Tj ET Q q 0 0 0 rg BT 395.62 449.25 Td (fr) Tj ET Q q 0 0 0 rg BT 401.92 449.25 Td (om ) Tj ET Q q 0 0 0 rg BT 416.64 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 431.36 449.25 Td (EU. ) Tj ET Q q 0 0 0 rg BT 449.70 449.25 Td (Of ) Tj ET Q q 0 0 0 rg BT 462.20 449.25 Td (note, ) Tj ET Q q 0 0 0 rg BT 484.42 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 499.14 449.25 Td (exit ) Tj ET Q q 0 0 0 rg BT 516.08 449.25 Td (of ) Tj ET Q q 0 0 0 rg BT 526.36 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 541.08 449.25 Td (UK ) Tj ET Q q 0 0 0 rg BT 557.48 449.25 Td (fr) Tj ET Q q 0 0 0 rg BT 563.78 449.25 Td (om ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.28 437.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 67.67 437.25 Td (may ) Tj ET Q q 0 0 0 rg BT 87.40 437.25 Td (have ) Tj ET Q q 0 0 0 rg BT 109.34 437.25 Td (an ) Tj ET Q q 0 0 0 rg BT 122.40 437.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 152.68 437.25 Td (on ) Tj ET Q q 0 0 0 rg BT 165.75 437.25 Td (our ) Tj ET Q q 0 0 0 rg BT 182.70 437.25 Td (r) Tj ET Q q 0 0 0 rg BT 186.22 437.25 Td (esear) Tj ET Q q 0 0 0 rg BT 207.51 437.25 Td (ch, ) Tj ET Q q 0 0 0 rg BT 222.52 437.25 Td (commer) Tj ET Q q 0 0 0 rg BT 254.36 437.25 Td (cial ) Tj ET Q q 0 0 0 rg BT 272.42 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 290.48 437.25 Td (general ) Tj ET Q q 0 0 0 rg BT 324.09 437.25 Td (business ) Tj ET Q q 0 0 0 rg BT 361.05 437.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 406.89 437.25 Td (in ) Tj ET Q q 0 0 0 rg BT 417.73 437.25 Td (the ) Tj ET Q q 0 0 0 rg BT 433.01 437.25 Td (UK ) Tj ET Q q 0 0 0 rg BT 449.97 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 468.03 437.25 Td (the ) Tj ET Q q 0 0 0 rg BT 483.31 437.25 Td (EU. ) Tj ET Q q 0 0 0 rg BT 502.21 437.25 Td (In ) Tj ET Q q 0 0 0 rg BT 513.60 437.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 552.50 437.25 Td (futur) Tj ET Q q 0 0 0 rg BT 571.58 437.25 Td (e ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (pension ) Tj ET Q q 0 0 0 rg BT 70.34 425.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 91.35 425.25 Td (funding ) Tj ET Q q 0 0 0 rg BT 125.14 425.25 Td (r) Tj ET Q q 0 0 0 rg BT 128.66 425.25 Td (equir) Tj ET Q q 0 0 0 rg BT 149.40 425.25 Td (ements ) Tj ET Q q 0 0 0 rg BT 180.40 425.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 218.06 425.25 Td (to ) Tj ET Q q 0 0 0 rg BT 229.07 425.25 Td (be ) Tj ET Q q 0 0 0 rg BT 241.74 425.25 Td (sensitive ) Tj ET Q q 0 0 0 rg BT 279.41 425.25 Td (to ) Tj ET Q q 0 0 0 rg BT 290.42 425.25 Td (global ) Tj ET Q q 0 0 0 rg BT 319.20 425.25 Td (economic ) Tj ET Q q 0 0 0 rg BT 360.75 425.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 405.65 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 423.88 425.25 Td (the ) Tj ET Q q 0 0 0 rg BT 439.33 425.25 Td (r) Tj ET Q q 0 0 0 rg BT 442.85 425.25 Td (elated ) Tj ET Q q 0 0 0 rg BT 470.51 425.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 500.96 425.25 Td (on ) Tj ET Q q 0 0 0 rg BT 514.19 425.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 541.86 425.25 Td (markets. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (Additionally) Tj ET Q q 0 0 0 rg BT 84.89 413.25 Td (, ) Tj ET Q q 0 0 0 rg BT 89.49 413.25 Td (disruptions ) Tj ET Q q 0 0 0 rg BT 136.59 413.25 Td (in ) Tj ET Q q 0 0 0 rg BT 146.47 413.25 Td (the ) Tj ET Q q 0 0 0 rg BT 160.79 413.25 Td (cr) Tj ET Q q 0 0 0 rg BT 168.75 413.25 Td (edit ) Tj ET Q q 0 0 0 rg BT 185.84 413.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 219.60 413.25 Td (or ) Tj ET Q q 0 0 0 rg BT 230.59 413.25 Td (a ) Tj ET Q q 0 0 0 rg BT 237.69 413.25 Td (downgrade ) Tj ET Q q 0 0 0 rg BT 284.79 413.25 Td (of ) Tj ET Q q 0 0 0 rg BT 294.66 413.25 Td (our ) Tj ET Q q 0 0 0 rg BT 310.65 413.25 Td (curr) Tj ET Q q 0 0 0 rg BT 327.50 413.25 Td (ent ) Tj ET Q q 0 0 0 rg BT 341.82 413.25 Td (cr) Tj ET Q q 0 0 0 rg BT 349.78 413.25 Td (edit ) Tj ET Q q 0 0 0 rg BT 366.87 413.25 Td (rating ) Tj ET Q q 0 0 0 rg BT 393.42 413.25 Td (could ) Tj ET Q q 0 0 0 rg BT 417.73 413.25 Td (incr) Tj ET Q q 0 0 0 rg BT 433.47 413.25 Td (ease ) Tj ET Q q 0 0 0 rg BT 453.34 413.25 Td (our ) Tj ET Q q 0 0 0 rg BT 469.33 413.25 Td (futur) Tj ET Q q 0 0 0 rg BT 488.41 413.25 Td (e ) Tj ET Q q 0 0 0 rg BT 494.94 413.25 Td (borr) Tj ET Q q 0 0 0 rg BT 512.35 413.25 Td (owing ) Tj ET Q q 0 0 0 rg BT 538.90 413.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 561.00 413.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (impair ) Tj ET Q q 0 0 0 rg BT 64.67 401.25 Td (our ) Tj ET Q q 0 0 0 rg BT 80.56 401.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 108.12 401.25 Td (to ) Tj ET Q q 0 0 0 rg BT 117.90 401.25 Td (access ) Tj ET Q q 0 0 0 rg BT 146.00 401.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 175.77 401.25 Td (and ) Tj ET Q q 0 0 0 rg BT 192.77 401.25 Td (cr) Tj ET Q q 0 0 0 rg BT 200.73 401.25 Td (edit ) Tj ET Q q 0 0 0 rg BT 217.73 401.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 251.39 401.25 Td (on ) Tj ET Q q 0 0 0 rg BT 263.39 401.25 Td (terms ) Tj ET Q q 0 0 0 rg BT 287.61 401.25 Td (commer) Tj ET Q q 0 0 0 rg BT 319.45 401.25 Td (cially ) Tj ET Q q 0 0 0 rg BT 343.66 401.25 Td (acceptable ) Tj ET Q q 0 0 0 rg BT 388.98 401.25 Td (to ) Tj ET Q q 0 0 0 rg BT 398.75 401.25 Td (us, ) Tj ET Q q 0 0 0 rg BT 412.15 401.25 Td (which ) Tj ET Q q 0 0 0 rg BT 438.04 401.25 Td (could ) Tj ET Q q 0 0 0 rg BT 462.25 401.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 502.57 401.25 Td (affect ) Tj ET Q q 0 0 0 rg BT 526.78 401.25 Td (our ) Tj ET Q q 0 0 0 rg BT 542.67 401.25 Td (liquidity ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.92 389.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 82.61 389.25 Td (r) Tj ET Q q 0 0 0 rg BT 86.13 389.25 Td (esour) Tj ET Q q 0 0 0 rg BT 107.99 389.25 Td (ces ) Tj ET Q q 0 0 0 rg BT 122.67 389.25 Td (or ) Tj ET Q q 0 0 0 rg BT 133.49 389.25 Td (significantly ) Tj ET Q q 0 0 0 rg BT 184.85 389.25 Td (incr) Tj ET Q q 0 0 0 rg BT 200.58 389.25 Td (ease ) Tj ET Q q 0 0 0 rg BT 220.27 389.25 Td (our ) Tj ET Q q 0 0 0 rg BT 236.08 389.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 254.11 389.25 Td (of ) Tj ET Q q 0 0 0 rg BT 263.81 389.25 Td (capital. ) Tj ET Q q 0 0 0 rg BT 296.00 389.25 Td (Finally) Tj ET Q q 0 0 0 rg BT 324.33 389.25 Td (, ) Tj ET Q q 0 0 0 rg BT 328.76 389.25 Td (our ) Tj ET Q q 0 0 0 rg BT 344.57 389.25 Td (business, ) Tj ET Q q 0 0 0 rg BT 382.88 389.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 427.58 389.25 Td (may ) Tj ET Q q 0 0 0 rg BT 446.16 389.25 Td (be ) Tj ET Q q 0 0 0 rg BT 457.52 389.25 Td (adversely ) Tj ET Q q 0 0 0 rg BT 497.75 389.25 Td (affected ) Tj ET Q q 0 0 0 rg BT 531.32 389.25 Td (by ) Tj ET Q q 0 0 0 rg BT 542.68 389.25 Td (political ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 377.25 Td (volatility) Tj ET Q q 0 0 0 rg BT 71.00 377.25 Td (, ) Tj ET Q q 0 0 0 rg BT 76.00 377.25 Td (conflicts ) Tj ET Q q 0 0 0 rg BT 112.38 377.25 Td (or ) Tj ET Q q 0 0 0 rg BT 123.77 377.25 Td (crises ) Tj ET Q q 0 0 0 rg BT 149.60 377.25 Td (in ) Tj ET Q q 0 0 0 rg BT 159.88 377.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 202.93 377.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 242.65 377.25 Td (or ) Tj ET Q q 0 0 0 rg BT 254.04 377.25 Td (r) Tj ET Q q 0 0 0 rg BT 257.56 377.25 Td (egions, ) Tj ET Q q 0 0 0 rg BT 288.67 377.25 Td (including ) Tj ET Q q 0 0 0 rg BT 328.94 377.25 Td (terr) Tj ET Q q 0 0 0 rg BT 343.57 377.25 Td (orist ) Tj ET Q q 0 0 0 rg BT 364.41 377.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 403.01 377.25 Td (or ) Tj ET Q q 0 0 0 rg BT 414.40 377.25 Td (war) Tj ET Q q 0 0 0 rg BT 428.85 377.25 Td (. ) Tj ET Q q 0 0 0 rg BT 433.85 377.25 Td ( ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 347.85 Td (There ) Tj ET Q q 0 0 0 rg BT 62.94 347.85 Td (can ) Tj ET Q q 0 0 0 rg BT 80.44 347.85 Td (be ) Tj ET Q q 0 0 0 rg BT 92.38 347.85 Td (no ) Tj ET Q q 0 0 0 rg BT 105.44 347.85 Td (guarantee ) Tj ET Q q 0 0 0 rg BT 149.61 347.85 Td (that ) Tj ET Q q 0 0 0 rg BT 168.23 347.85 Td (we ) Tj ET Q q 0 0 0 rg BT 181.83 347.85 Td (will ) Tj ET Q q 0 0 0 rg BT 199.34 347.85 Td (pay ) Tj ET Q q 0 0 0 rg BT 216.28 347.85 Td (dividends ) Tj ET Q q 0 0 0 rg BT 257.67 347.85 Td (or ) Tj ET Q q 0 0 0 rg BT 269.06 347.85 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 317.67 347.85 Td (stock.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 335.85 Td (The ) Tj ET Q q 0 0 0 rg BT 52.80 335.85 Td (declaration, ) Tj ET Q q 0 0 0 rg BT 103.20 335.85 Td (amount ) Tj ET Q q 0 0 0 rg BT 134.99 335.85 Td (and ) Tj ET Q q 0 0 0 rg BT 151.79 335.85 Td (timing ) Tj ET Q q 0 0 0 rg BT 179.14 335.85 Td (of ) Tj ET Q q 0 0 0 rg BT 188.71 335.85 Td (any ) Tj ET Q q 0 0 0 rg BT 204.95 335.85 Td (dividends ) Tj ET Q q 0 0 0 rg BT 245.07 335.85 Td (fall ) Tj ET Q q 0 0 0 rg BT 260.20 335.85 Td (within ) Tj ET Q q 0 0 0 rg BT 287.00 335.85 Td (the ) Tj ET Q q 0 0 0 rg BT 301.01 335.85 Td (discr) Tj ET Q q 0 0 0 rg BT 320.64 335.85 Td (etion ) Tj ET Q q 0 0 0 rg BT 342.43 335.85 Td (of ) Tj ET Q q 0 0 0 rg BT 352.01 335.85 Td (our ) Tj ET Q q 0 0 0 rg BT 367.70 335.85 Td (Boar) Tj ET Q q 0 0 0 rg BT 387.32 335.85 Td (d ) Tj ET Q q 0 0 0 rg BT 394.12 335.85 Td (of ) Tj ET Q q 0 0 0 rg BT 403.69 335.85 Td (Dir) Tj ET Q q 0 0 0 rg BT 417.21 335.85 Td (ectors. ) Tj ET Q q 0 0 0 rg BT 445.95 335.85 Td (The ) Tj ET Q q 0 0 0 rg BT 462.75 335.85 Td (Boar) Tj ET Q q 0 0 0 rg BT 482.37 335.85 Td (d's ) Tj ET Q q 0 0 0 rg BT 495.20 335.85 Td (decision ) Tj ET Q q 0 0 0 rg BT 530.32 335.85 Td (will ) Tj ET Q q 0 0 0 rg BT 547.12 335.85 Td (depend ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 323.85 Td (on ) Tj ET Q q 0 0 0 rg BT 49.31 323.85 Td (many ) Tj ET Q q 0 0 0 rg BT 74.29 323.85 Td (factors, ) Tj ET Q q 0 0 0 rg BT 107.88 323.85 Td (including ) Tj ET Q q 0 0 0 rg BT 148.96 323.85 Td (our ) Tj ET Q q 0 0 0 rg BT 166.17 323.85 Td (financial ) Tj ET Q q 0 0 0 rg BT 205.03 323.85 Td (condition, ) Tj ET Q q 0 0 0 rg BT 248.62 323.85 Td (earnings, ) Tj ET Q q 0 0 0 rg BT 289.43 323.85 Td (capital ) Tj ET Q q 0 0 0 rg BT 320.52 323.85 Td (r) Tj ET Q q 0 0 0 rg BT 324.04 323.85 Td (equir) Tj ET Q q 0 0 0 rg BT 344.78 323.85 Td (ements, ) Tj ET Q q 0 0 0 rg BT 378.36 323.85 Td (debt ) Tj ET Q q 0 0 0 rg BT 398.89 323.85 Td (service ) Tj ET Q q 0 0 0 rg BT 430.52 323.85 Td (obligations, ) Tj ET Q q 0 0 0 rg BT 481.33 323.85 Td (industry ) Tj ET Q q 0 0 0 rg BT 517.43 323.85 Td (practice, ) Tj ET Q q 0 0 0 rg BT 556.00 323.85 Td (legal ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 311.85 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 311.85 Td (equir) Tj ET Q q 0 0 0 rg BT 60.26 311.85 Td (ements, ) Tj ET Q q 0 0 0 rg BT 92.79 311.85 Td (r) Tj ET Q q 0 0 0 rg BT 96.31 311.85 Td (egulatory ) Tj ET Q q 0 0 0 rg BT 136.90 311.85 Td (constraints ) Tj ET Q q 0 0 0 rg BT 183.61 311.85 Td (and ) Tj ET Q q 0 0 0 rg BT 200.87 311.85 Td (other ) Tj ET Q q 0 0 0 rg BT 224.24 311.85 Td (factors ) Tj ET Q q 0 0 0 rg BT 254.29 311.85 Td (that ) Tj ET Q q 0 0 0 rg BT 272.11 311.85 Td (our ) Tj ET Q q 0 0 0 rg BT 288.26 311.85 Td (Boar) Tj ET Q q 0 0 0 rg BT 307.89 311.85 Td (d ) Tj ET Q q 0 0 0 rg BT 315.15 311.85 Td (of ) Tj ET Q q 0 0 0 rg BT 325.19 311.85 Td (Dir) Tj ET Q q 0 0 0 rg BT 338.71 311.85 Td (ectors ) Tj ET Q q 0 0 0 rg BT 365.42 311.85 Td (may ) Tj ET Q q 0 0 0 rg BT 384.34 311.85 Td (deem ) Tj ET Q q 0 0 0 rg BT 407.70 311.85 Td (r) Tj ET Q q 0 0 0 rg BT 411.22 311.85 Td (elevant. ) Tj ET Q q 0 0 0 rg BT 444.69 311.85 Td (A) Tj ET Q q 0 0 0 rg BT 450.62 311.85 Td ( ) Tj ET Q q 0 0 0 rg BT 452.88 311.85 Td (r) Tj ET Q q 0 0 0 rg BT 456.41 311.85 Td (eduction ) Tj ET Q q 0 0 0 rg BT 493.10 311.85 Td (or ) Tj ET Q q 0 0 0 rg BT 504.26 311.85 Td (elimination ) Tj ET Q q 0 0 0 rg BT 552.07 311.85 Td (of ) Tj ET Q q 0 0 0 rg BT 562.11 311.85 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 299.85 Td (dividend ) Tj ET Q q 0 0 0 rg BT 72.60 299.85 Td (payments ) Tj ET Q q 0 0 0 rg BT 112.54 299.85 Td (or ) Tj ET Q q 0 0 0 rg BT 123.60 299.85 Td (dividend ) Tj ET Q q 0 0 0 rg BT 160.21 299.85 Td (pr) Tj ET Q q 0 0 0 rg BT 168.73 299.85 Td (ogram ) Tj ET Q q 0 0 0 rg BT 197.01 299.85 Td (could ) Tj ET Q q 0 0 0 rg BT 221.39 299.85 Td (adversely ) Tj ET Q q 0 0 0 rg BT 261.88 299.85 Td (affect ) Tj ET Q q 0 0 0 rg BT 286.26 299.85 Td (our ) Tj ET Q q 0 0 0 rg BT 302.32 299.85 Td (stock ) Tj ET Q q 0 0 0 rg BT 325.04 299.85 Td (price. ) Tj ET Q q 0 0 0 rg BT 350.25 299.85 Td (In ) Tj ET Q q 0 0 0 rg BT 360.75 299.85 Td (addition, ) Tj ET Q q 0 0 0 rg BT 398.76 299.85 Td (we ) Tj ET Q q 0 0 0 rg BT 412.04 299.85 Td (could, ) Tj ET Q q 0 0 0 rg BT 438.92 299.85 Td (at ) Tj ET Q q 0 0 0 rg BT 448.87 299.85 Td (any ) Tj ET Q q 0 0 0 rg BT 465.48 299.85 Td (time, ) Tj ET Q q 0 0 0 rg BT 487.36 299.85 Td (decide ) Tj ET Q q 0 0 0 rg BT 515.63 299.85 Td (not ) Tj ET Q q 0 0 0 rg BT 530.58 299.85 Td (to ) Tj ET Q q 0 0 0 rg BT 540.52 299.85 Td (buy ) Tj ET Q q 0 0 0 rg BT 557.13 299.85 Td (back ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 287.85 Td (any ) Tj ET Q q 0 0 0 rg BT 52.94 287.85 Td (mor) Tj ET Q q 0 0 0 rg BT 68.68 287.85 Td (e ) Tj ET Q q 0 0 0 rg BT 75.62 287.85 Td (shar) Tj ET Q q 0 0 0 rg BT 93.03 287.85 Td (es ) Tj ET Q q 0 0 0 rg BT 103.86 287.85 Td (in ) Tj ET Q q 0 0 0 rg BT 114.14 287.85 Td (the ) Tj ET Q q 0 0 0 rg BT 128.86 287.85 Td (market, ) Tj ET Q q 0 0 0 rg BT 161.63 287.85 Td (which ) Tj ET Q q 0 0 0 rg BT 188.01 287.85 Td (could ) Tj ET Q q 0 0 0 rg BT 212.73 287.85 Td (also ) Tj ET Q q 0 0 0 rg BT 231.90 287.85 Td (adversely ) Tj ET Q q 0 0 0 rg BT 272.71 287.85 Td (affect ) Tj ET Q q 0 0 0 rg BT 297.43 287.85 Td (our ) Tj ET Q q 0 0 0 rg BT 313.82 287.85 Td (stock ) Tj ET Q q 0 0 0 rg BT 336.86 287.85 Td (price.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 263.85 Td (Increased ) Tj ET Q q 0 0 0 rg BT 79.05 263.85 Td (use ) Tj ET Q q 0 0 0 rg BT 95.44 263.85 Td (of ) Tj ET Q q 0 0 0 rg BT 106.27 263.85 Td (social ) Tj ET Q q 0 0 0 rg BT 132.66 263.85 Td (media ) Tj ET Q q 0 0 0 rg BT 160.16 263.85 Td (platforms ) Tj ET Q q 0 0 0 rg BT 202.10 263.85 Td (present ) Tj ET Q q 0 0 0 rg BT 234.60 263.85 Td (risks ) Tj ET Q q 0 0 0 rg BT 256.56 263.85 Td (and ) Tj ET Q q 0 0 0 rg BT 274.62 263.85 Td (challenges.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 251.85 Td (W) Tj ET Q q 0 0 0 rg BT 43.41 251.85 Td (e ) Tj ET Q q 0 0 0 rg BT 50.87 251.85 Td (ar) Tj ET Q q 0 0 0 rg BT 59.39 251.85 Td (e ) Tj ET Q q 0 0 0 rg BT 66.85 251.85 Td (incr) Tj ET Q q 0 0 0 rg BT 82.59 251.85 Td (easing ) Tj ET Q q 0 0 0 rg BT 111.72 251.85 Td (our ) Tj ET Q q 0 0 0 rg BT 128.63 251.85 Td (use ) Tj ET Q q 0 0 0 rg BT 144.98 251.85 Td (of ) Tj ET Q q 0 0 0 rg BT 155.78 251.85 Td (social ) Tj ET Q q 0 0 0 rg BT 182.68 251.85 Td (media ) Tj ET Q q 0 0 0 rg BT 210.14 251.85 Td (to ) Tj ET Q q 0 0 0 rg BT 220.94 251.85 Td (communicate ) Tj ET Q q 0 0 0 rg BT 277.27 251.85 Td (Company ) Tj ET Q q 0 0 0 rg BT 318.62 251.85 Td (news ) Tj ET Q q 0 0 0 rg BT 341.64 251.85 Td (and ) Tj ET Q q 0 0 0 rg BT 359.66 251.85 Td (events. ) Tj ET Q q 0 0 0 rg BT 390.17 251.85 Td (The ) Tj ET Q q 0 0 0 rg BT 408.19 251.85 Td (inappr) Tj ET Q q 0 0 0 rg BT 434.49 251.85 Td (opriate ) Tj ET Q q 0 0 0 rg BT 466.40 251.85 Td (and/or ) Tj ET Q q 0 0 0 rg BT 496.09 251.85 Td (unauthorized ) Tj ET Q q 0 0 0 rg BT 551.88 251.85 Td (use ) Tj ET Q q 0 0 0 rg BT 568.23 251.85 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 239.85 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.11 239.85 Td (media ) Tj ET Q q 0 0 0 rg BT 92.33 239.85 Td (vehicles ) Tj ET Q q 0 0 0 rg BT 126.32 239.85 Td (could ) Tj ET Q q 0 0 0 rg BT 150.32 239.85 Td (cause ) Tj ET Q q 0 0 0 rg BT 174.87 239.85 Td (brand ) Tj ET Q q 0 0 0 rg BT 200.54 239.85 Td (damage ) Tj ET Q q 0 0 0 rg BT 233.99 239.85 Td (or ) Tj ET Q q 0 0 0 rg BT 244.66 239.85 Td (information ) Tj ET Q q 0 0 0 rg BT 293.67 239.85 Td (leakage ) Tj ET Q q 0 0 0 rg BT 326.55 239.85 Td (or ) Tj ET Q q 0 0 0 rg BT 337.23 239.85 Td (could ) Tj ET Q q 0 0 0 rg BT 361.23 239.85 Td (lead ) Tj ET Q q 0 0 0 rg BT 380.23 239.85 Td (to ) Tj ET Q q 0 0 0 rg BT 389.79 239.85 Td (legal ) Tj ET Q q 0 0 0 rg BT 411.57 239.85 Td (implications, ) Tj ET Q q 0 0 0 rg BT 465.30 239.85 Td (including ) Tj ET Q q 0 0 0 rg BT 504.85 239.85 Td (fr) Tj ET Q q 0 0 0 rg BT 511.15 239.85 Td (om ) Tj ET Q q 0 0 0 rg BT 525.16 239.85 Td (the ) Tj ET Q q 0 0 0 rg BT 539.16 239.85 Td (impr) Tj ET Q q 0 0 0 rg BT 557.68 239.85 Td (oper ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 227.85 Td (collection ) Tj ET Q q 0 0 0 rg BT 79.54 227.85 Td (and/or ) Tj ET Q q 0 0 0 rg BT 110.31 227.85 Td (dissemination ) Tj ET Q q 0 0 0 rg BT 169.97 227.85 Td (of ) Tj ET Q q 0 0 0 rg BT 181.86 227.85 Td (personally ) Tj ET Q q 0 0 0 rg BT 228.18 227.85 Td (identifiable ) Tj ET Q q 0 0 0 rg BT 277.84 227.85 Td (information ) Tj ET Q q 0 0 0 rg BT 329.17 227.85 Td (fr) Tj ET Q q 0 0 0 rg BT 335.47 227.85 Td (om ) Tj ET Q q 0 0 0 rg BT 351.80 227.85 Td (employees, ) Tj ET Q q 0 0 0 rg BT 400.05 227.85 Td (patients, ) Tj ET Q q 0 0 0 rg BT 438.32 227.85 Td (healthcar) Tj ET Q q 0 0 0 rg BT 476.27 227.85 Td (e ) Tj ET Q q 0 0 0 rg BT 484.82 227.85 Td (pr) Tj ET Q q 0 0 0 rg BT 493.34 227.85 Td (ofessionals ) Tj ET Q q 0 0 0 rg BT 541.89 227.85 Td (or ) Tj ET Q q 0 0 0 rg BT 554.89 227.85 Td (other ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 215.85 Td (stakeholders. ) Tj ET Q q 0 0 0 rg BT 92.66 215.85 Td (In ) Tj ET Q q 0 0 0 rg BT 104.61 215.85 Td (addition, ) Tj ET Q q 0 0 0 rg BT 144.06 215.85 Td (negative ) Tj ET Q q 0 0 0 rg BT 181.54 215.85 Td (or ) Tj ET Q q 0 0 0 rg BT 194.05 215.85 Td (inaccurate ) Tj ET Q q 0 0 0 rg BT 240.43 215.85 Td (posts ) Tj ET Q q 0 0 0 rg BT 264.60 215.85 Td (or ) Tj ET Q q 0 0 0 rg BT 277.11 215.85 Td (comments ) Tj ET Q q 0 0 0 rg BT 320.72 215.85 Td (about ) Tj ET Q q 0 0 0 rg BT 347.11 215.85 Td (us ) Tj ET Q q 0 0 0 rg BT 359.61 215.85 Td (on ) Tj ET Q q 0 0 0 rg BT 373.23 215.85 Td (any ) Tj ET Q q 0 0 0 rg BT 391.28 215.85 Td (social ) Tj ET Q q 0 0 0 rg BT 418.78 215.85 Td (networking ) Tj ET Q q 0 0 0 rg BT 467.39 215.85 Td (website ) Tj ET Q q 0 0 0 rg BT 501.00 215.85 Td (could ) Tj ET Q q 0 0 0 rg BT 526.84 215.85 Td (damage ) Tj ET Q q 0 0 0 rg BT 562.11 215.85 Td (our ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 203.85 Td (r) Tj ET Q q 0 0 0 rg BT 39.52 203.85 Td (eputation, ) Tj ET Q q 0 0 0 rg BT 82.18 203.85 Td (brand ) Tj ET Q q 0 0 0 rg BT 108.45 203.85 Td (image ) Tj ET Q q 0 0 0 rg BT 135.27 203.85 Td (and ) Tj ET Q q 0 0 0 rg BT 152.65 203.85 Td (goodwill. ) Tj ET Q q 0 0 0 rg BT 192.54 203.85 Td (Further) Tj ET Q q 0 0 0 rg BT 222.54 203.85 Td (, ) Tj ET Q q 0 0 0 rg BT 227.42 203.85 Td (the ) Tj ET Q q 0 0 0 rg BT 242.02 203.85 Td (disclosur) Tj ET Q q 0 0 0 rg BT 278.32 203.85 Td (e ) Tj ET Q q 0 0 0 rg BT 285.14 203.85 Td (of ) Tj ET Q q 0 0 0 rg BT 295.30 203.85 Td (non-public ) Tj ET Q q 0 0 0 rg BT 341.00 203.85 Td (Company-sensitive ) Tj ET Q q 0 0 0 rg BT 419.48 203.85 Td (information ) Tj ET Q q 0 0 0 rg BT 469.09 203.85 Td (by ) Tj ET Q q 0 0 0 rg BT 480.91 203.85 Td (our ) Tj ET Q q 0 0 0 rg BT 497.18 203.85 Td (workfor) Tj ET Q q 0 0 0 rg BT 528.48 203.85 Td (ce ) Tj ET Q q 0 0 0 rg BT 539.74 203.85 Td (or ) Tj ET Q q 0 0 0 rg BT 551.01 203.85 Td (others ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 191.85 Td (thr) Tj ET Q q 0 0 0 rg BT 47.30 191.85 Td (ough ) Tj ET Q q 0 0 0 rg BT 70.41 191.85 Td (external ) Tj ET Q q 0 0 0 rg BT 106.28 191.85 Td (media ) Tj ET Q q 0 0 0 rg BT 133.82 191.85 Td (channels ) Tj ET Q q 0 0 0 rg BT 172.48 191.85 Td (could ) Tj ET Q q 0 0 0 rg BT 197.80 191.85 Td (lead ) Tj ET Q q 0 0 0 rg BT 218.13 191.85 Td (to ) Tj ET Q q 0 0 0 rg BT 229.02 191.85 Td (information ) Tj ET Q q 0 0 0 rg BT 279.35 191.85 Td (loss. ) Tj ET Q q 0 0 0 rg BT 300.52 191.85 Td (Identifying ) Tj ET Q q 0 0 0 rg BT 346.95 191.85 Td (new ) Tj ET Q q 0 0 0 rg BT 366.16 191.85 Td (points ) Tj ET Q q 0 0 0 rg BT 393.72 191.85 Td (of ) Tj ET Q q 0 0 0 rg BT 404.61 191.85 Td (entry ) Tj ET Q q 0 0 0 rg BT 428.26 191.85 Td (as ) Tj ET Q q 0 0 0 rg BT 440.26 191.85 Td (social ) Tj ET Q q 0 0 0 rg BT 467.25 191.85 Td (media ) Tj ET Q q 0 0 0 rg BT 494.80 191.85 Td (continues ) Tj ET Q q 0 0 0 rg BT 536.23 191.85 Td (to ) Tj ET Q q 0 0 0 rg BT 547.12 191.85 Td (expand ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 179.85 Td (pr) Tj ET Q q 0 0 0 rg BT 44.52 179.85 Td (esents ) Tj ET Q q 0 0 0 rg BT 71.46 179.85 Td (new ) Tj ET Q q 0 0 0 rg BT 90.07 179.85 Td (challenges.) 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Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 523.23 Td (LEGAL) Tj ET Q q 0 0 0 rg BT 129.46 523.23 Td ( PROCEEDINGS.) 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Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 451.23 Td (Item 4.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 451.23 Td (MINE SAFETY) Tj ET Q q 0 0 0 rg BT 163.80 451.23 Td ( DISCLOSURES.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 423.00 Td (Not applicable.) 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Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 39 674.86259765625 m 156.87109375 674.86259765625 l s q 0 0 0 rg BT 39.00 676.43 Td (Name and Curr) Tj ET Q q 0 0 0 rg BT 106.68 676.43 Td (ent Position) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 225.15 674.86259765625 m 241.81015625 674.86259765625 l s q 0 0 0 rg BT 225.15 676.43 Td (Age) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 252 674.86259765625 m 426.9755859375 674.86259765625 l s q 0 0 0 rg BT 252.00 676.43 Td (Employment History for) Tj ET Q q 0 0 0 rg BT 356.80 676.43 Td ( the Past 5 ) Tj ET Q q 0 0 0 rg BT 403.09 676.43 Td (Y) Tj ET Q q 0 0 0 rg BT 409.21 676.43 Td (ears) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 662.32 Td (Giovanni Caforio, M.D. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 652.31 Td (Chairman of the Boar) Tj ET Q q 0 0 0 rg BT 126.69 652.31 Td (d and Chief Executive ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 642.31 Td (Officer) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 632.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 632.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 662.32 Td (53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 662.32 Td (201) Tj ET Q q 0 0 0 rg BT 266.63 662.32 Td (1 ) Tj ET Q q 0 0 0 rg BT 274.13 662.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.41 662.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 306.91 662.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.41 662.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 356.62 662.32 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 376.91 662.32 Td (Pharmaceuticals) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 652.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 274.50 652.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 652.32 Td (2014 ) Tj ET Q q 0 0 0 rg BT 307.28 652.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 652.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 357.08 652.32 Td (V) Tj ET Q q 0 0 0 rg BT 363.70 652.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 377.85 652.32 Td (President ) Tj ET Q q 0 0 0 rg BT 417.57 652.32 Td (and ) Tj ET Q q 0 0 0 rg BT 434.51 652.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 459.23 652.32 Td (Commercial ) Tj ET Q q 0 0 0 rg BT 511.16 652.32 Td (Of) Tj ET Q q 0 0 0 rg BT 521.53 652.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 642.32 Td (2014 ) Tj ET Q q 0 0 0 rg BT 274.50 642.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 642.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 307.28 642.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 642.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 339.50 642.32 Td (Operating ) Tj ET Q q 0 0 0 rg BT 381.98 642.32 Td (Of) Tj ET Q q 0 0 0 rg BT 392.35 642.32 Td (ficer ) Tj ET Q q 0 0 0 rg BT 413.17 642.32 Td (and ) Tj ET Q q 0 0 0 rg BT 430.11 642.32 Td (Director ) Tj ET Q q 0 0 0 rg BT 465.92 642.32 Td (of ) Tj ET Q q 0 0 0 rg BT 476.75 642.32 Td (the ) Tj ET Q q 0 0 0 rg BT 491.47 642.32 Td (Company) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 632.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 274.50 632.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 632.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 307.28 632.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 632.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 339.50 632.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 381.98 632.32 Td (Of) Tj ET Q q 0 0 0 rg BT 392.35 632.32 Td (ficer ) Tj ET Q q 0 0 0 rg BT 413.16 632.32 Td (and ) Tj ET Q q 0 0 0 rg BT 430.10 632.32 Td (Director ) Tj ET Q q 0 0 0 rg BT 465.92 632.32 Td (of ) Tj ET Q q 0 0 0 rg BT 476.75 632.32 Td (the ) Tj ET Q q 0 0 0 rg BT 491.46 632.32 Td (Company) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 622.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 274.50 622.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 622.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 622.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 622.32 Td (Chairman ) Tj ET Q q 0 0 0 rg BT 365.59 622.32 Td (of ) Tj ET Q q 0 0 0 rg BT 376.42 622.32 Td (the ) Tj ET Q q 0 0 0 rg BT 391.14 622.32 Td (Board ) Tj ET Q q 0 0 0 rg BT 418.07 622.32 Td (and ) Tj ET Q q 0 0 0 rg BT 435.01 622.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 459.73 622.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 502.21 622.32 Td (Of) Tj ET Q q 0 0 0 rg BT 512.58 622.32 Td (ficer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 605.32 Td (Charles ) Tj ET Q q 0 0 0 rg BT 71.50 605.32 Td (A. Bancroft ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 595.31 Td (Chief Financial Officer and Executive V) Tj ET Q q 0 0 0 rg BT 199.60 595.31 Td (ice ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 585.31 Td (Pr) Tj ET Q q 0 0 0 rg BT 48.63 585.31 Td (esident, Global Business Operations) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 575.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 575.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 605.32 Td (58) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 605.32 Td (201) Tj ET Q q 0 0 0 rg BT 266.63 605.32 Td (1 to 2016 - Chief Financial Of) Tj ET Q q 0 0 0 rg BT 387.54 605.32 Td (ficer and Executive ) Tj ET Q q 0 0 0 rg BT 467.59 605.32 Td (V) Tj ET Q q 0 0 0 rg BT 474.21 605.32 Td (ice President, Global) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 595.32 Td (Services) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 585.32 Td (2016 to present - Chief Financial Of) Tj ET Q q 0 0 0 rg BT 396.79 585.32 Td (ficer and Executive ) Tj ET Q q 0 0 0 rg BT 476.84 585.32 Td (V) Tj ET Q q 0 0 0 rg BT 483.46 585.32 Td (ice President,) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 575.32 Td (Global Business Operations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 560.32 Td (Joseph C. Caldarella) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 550.31 Td (Senior V) Tj ET Q q 0 0 0 rg BT 72.97 550.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 96.76 550.31 Td (esident and Corporate ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 540.31 Td (Contr) Tj ET Q q 0 0 0 rg BT 61.97 540.31 Td (oller) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 560.32 Td (62) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 560.32 Td (2010 ) Tj ET Q q 0 0 0 rg BT 274.50 560.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 560.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 560.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 560.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 352.08 560.32 Td (V) Tj ET Q q 0 0 0 rg BT 358.70 560.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 372.86 560.32 Td (President ) Tj ET Q q 0 0 0 rg BT 412.58 560.32 Td (and ) Tj ET Q q 0 0 0 rg BT 429.51 560.32 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 472.00 560.32 Td (Controller) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 525.32 Td (John E. Elicker) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 515.31 Td (Senior V) Tj ET Q q 0 0 0 rg BT 72.97 515.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 96.76 515.31 Td (esident, Corporate ) Tj ET Q q 0 0 0 rg BT 174.07 515.31 Td (Affairs ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 505.31 Td (and Investor Relations) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 495.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 495.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 525.32 Td (58) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 525.32 Td (2012 ) Tj ET Q q 0 0 0 rg BT 274.50 525.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 525.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 307.28 525.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 525.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 343.21 525.32 Td (V) Tj ET Q q 0 0 0 rg BT 349.83 525.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 363.98 525.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 406.20 525.32 Td (Public ) Tj ET Q q 0 0 0 rg BT 433.70 525.32 Td (Af) Tj ET Q q 0 0 0 rg BT 444.08 525.32 Td (fairs ) Tj ET Q q 0 0 0 rg BT 464.34 525.32 Td (and ) Tj ET Q q 0 0 0 rg BT 481.28 525.32 Td (Investor ) Tj ET Q q 0 0 0 rg BT 516.55 525.32 Td (Relations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 515.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 277.24 515.32 Td (to ) Tj ET Q q 0 0 0 rg BT 290.27 515.32 Td (present ) Tj ET Q q 0 0 0 rg BT 324.39 515.32 Td (– ) Tj ET Q q 0 0 0 rg BT 334.63 515.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 365.61 515.32 Td (V) Tj ET Q q 0 0 0 rg BT 372.23 515.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 389.13 515.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 434.09 515.32 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 478.16 515.32 Td (Af) Tj ET Q q 0 0 0 rg BT 488.53 515.32 Td (fairs ) Tj ET Q q 0 0 0 rg BT 511.55 515.32 Td (and ) Tj ET Q q 0 0 0 rg BT 531.23 515.32 Td (Investor ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 505.32 Td (Relations ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 480.32 Td (Murdo Gordon) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 470.31 Td (Executive V) Tj ET Q q 0 0 0 rg BT 85.72 470.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 109.51 470.31 Td (esident, Chief ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 460.31 Td (Commer) Tj ET Q q 0 0 0 rg BT 73.07 460.31 Td (cial Officer) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 450.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 450.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 480.32 Td (51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 480.32 Td (201) Tj ET Q q 0 0 0 rg BT 266.63 480.32 Td (1 ) Tj ET Q q 0 0 0 rg BT 274.13 480.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.41 480.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 306.91 480.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.41 480.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 342.83 480.32 Td (V) Tj ET Q q 0 0 0 rg BT 349.46 480.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 363.61 480.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 405.83 480.32 Td (Oncology ) Tj ET Q q 0 0 0 rg BT 447.77 480.32 Td (and ) Tj ET Q q 0 0 0 rg BT 464.71 480.32 Td (Immunology) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 470.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 274.50 470.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 470.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 307.28 470.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 470.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 357.00 470.32 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 377.28 470.32 Td (Pharmaceuticals) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 460.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 274.50 460.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 460.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 307.28 460.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 460.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 343.21 460.32 Td (V) Tj ET Q q 0 0 0 rg BT 349.83 460.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 363.98 460.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 406.20 460.32 Td (Head ) Tj ET Q q 0 0 0 rg BT 429.80 460.32 Td (of ) Tj ET Q q 0 0 0 rg BT 440.45 460.32 Td (W) Tj ET Q q 0 0 0 rg BT 449.08 460.32 Td (orldwide ) Tj ET Q q 0 0 0 rg BT 487.13 460.32 Td (Markets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 450.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 274.50 450.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 450.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 450.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 450.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 365.96 450.32 Td (V) Tj ET Q q 0 0 0 rg BT 372.58 450.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 386.73 450.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 428.95 450.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 453.67 450.32 Td (Commercial ) Tj ET Q q 0 0 0 rg BT 505.59 450.32 Td (Of) Tj ET Q q 0 0 0 rg BT 515.96 450.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 435.32 Td (Ann Powell Judge) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 425.31 Td (Senior V) Tj ET Q q 0 0 0 rg BT 72.97 425.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 96.76 425.31 Td (esident, Chief Human ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 415.31 Td (Resour) Tj ET Q q 0 0 0 rg BT 66.96 415.31 Td (ces Officer) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 405.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 405.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 435.32 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 435.32 Td (2009 ) Tj ET Q q 0 0 0 rg BT 274.50 435.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 435.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 307.28 435.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 435.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 339.50 435.32 Td (Human ) Tj ET Q q 0 0 0 rg BT 371.43 435.32 Td (Resources ) Tj ET Q q 0 0 0 rg BT 415.03 435.32 Td (Of) Tj ET Q q 0 0 0 rg BT 425.40 435.32 Td (ficer) Tj ET Q q 0 0 0 rg BT 443.32 435.32 Td (, ) Tj ET Q q 0 0 0 rg BT 448.32 435.32 Td (Shire ) Tj ET Q q 0 0 0 rg BT 471.93 435.32 Td (Pharmaceuticals) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 424.32 Td (2013 ) Tj ET Q q 0 0 0 rg BT 274.50 424.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 424.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 307.28 424.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 424.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 343.21 424.32 Td (V) Tj ET Q q 0 0 0 rg BT 349.83 424.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 363.98 424.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 406.20 424.32 Td (Global ) Tj ET Q q 0 0 0 rg BT 435.92 424.32 Td (Human ) Tj ET Q q 0 0 0 rg BT 467.85 424.32 Td (Resources) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 414.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 274.50 414.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 414.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 414.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 414.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 352.08 414.32 Td (V) Tj ET Q q 0 0 0 rg BT 358.70 414.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 372.86 414.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 415.08 414.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 439.79 414.32 Td (Human ) Tj ET Q q 0 0 0 rg BT 471.73 414.32 Td (Resources ) Tj ET Q q 0 0 0 rg BT 515.33 414.32 Td (Of) Tj ET Q q 0 0 0 rg BT 525.70 414.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 388.32 Td (Sandra Leung ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 378.31 Td (Executive V) Tj ET Q q 0 0 0 rg BT 85.72 378.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 109.51 378.31 Td (esident, General Counsel) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 368.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 368.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 388.32 Td (57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 388.32 Td (2007 ) Tj ET Q q 0 0 0 rg BT 274.50 388.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 388.32 Td (2014 ) Tj ET Q q 0 0 0 rg BT 307.28 388.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.78 388.32 Td (General ) Tj ET Q q 0 0 0 rg BT 348.92 388.32 Td (Counsel ) Tj ET Q q 0 0 0 rg BT 384.20 388.32 Td (and ) Tj ET Q q 0 0 0 rg BT 401.14 388.32 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 443.63 388.32 Td (Secretary) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 378.32 Td (2014 ) Tj ET Q q 0 0 0 rg BT 276.27 378.32 Td (to ) Tj ET Q q 0 0 0 rg BT 288.32 378.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 312.59 378.32 Td (– ) Tj ET Q q 0 0 0 rg BT 321.86 378.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 365.81 378.32 Td (V) Tj ET Q q 0 0 0 rg BT 372.43 378.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 388.35 378.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 432.34 378.32 Td (General ) Tj ET Q q 0 0 0 rg BT 468.26 378.32 Td (Counsel ) Tj ET Q q 0 0 0 rg BT 505.31 378.32 Td (and ) Tj ET Q q 0 0 0 rg BT 524.02 378.32 Td (Corporate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 368.32 Td (Secretary) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 358.32 Td (2015 ) Tj ET Q q 0 0 0 rg BT 274.50 358.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 358.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 358.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 358.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 365.96 358.32 Td (V) Tj ET Q q 0 0 0 rg BT 372.58 358.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 386.73 358.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 428.95 358.32 Td (General ) Tj ET Q q 0 0 0 rg BT 463.09 358.32 Td (Counsel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 342.32 Td (Thomas J. L) Tj ET Q q 0 0 0 rg BT 88.17 342.32 Td (ynch., M.D. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 332.31 Td (Executive V) Tj ET Q q 0 0 0 rg BT 85.72 332.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 109.51 332.31 Td (esident and Chief ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 322.31 Td (Scientific Officer) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 312.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 312.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 342.32 Td (57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 342.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 274.50 342.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 342.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 342.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 342.32 Td (Executive ) Tj ET Q q 0 0 0 rg BT 365.96 342.32 Td (V) Tj ET Q q 0 0 0 rg BT 372.58 342.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 386.73 342.32 Td (President ) Tj ET Q q 0 0 0 rg BT 426.45 342.32 Td (and ) Tj ET Q q 0 0 0 rg BT 443.39 342.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 468.10 342.32 Td (Scientific ) Tj ET Q q 0 0 0 rg BT 508.92 342.32 Td (Of) Tj ET Q q 0 0 0 rg BT 519.29 342.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 297.32 Td (Louis S. Schmukler) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 287.31 Td (Senior V) Tj ET Q q 0 0 0 rg BT 72.97 287.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 96.76 287.31 Td (esident & Pr) Tj ET Q q 0 0 0 rg BT 147.49 287.31 Td (esident, Global ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 277.31 Td (Pr) Tj ET Q q 0 0 0 rg BT 48.63 277.31 Td (oduct Development and Supply) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 267.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 267.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 297.32 Td (62) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 297.32 Td (201) Tj ET Q q 0 0 0 rg BT 266.63 297.32 Td (1 ) Tj ET Q q 0 0 0 rg BT 274.13 297.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.41 297.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 306.91 297.32 Td (– ) Tj ET Q q 0 0 0 rg BT 314.41 297.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 356.62 297.32 Td (Global ) Tj ET Q q 0 0 0 rg BT 386.34 297.32 Td (Product ) Tj ET Q q 0 0 0 rg BT 419.95 297.32 Td (Development ) Tj ET Q q 0 0 0 rg BT 476.32 297.32 Td (and ) Tj ET Q q 0 0 0 rg BT 493.26 297.32 Td (Supply) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 287.32 Td (2017 ) Tj ET Q q 0 0 0 rg BT 278.34 287.32 Td (to ) Tj ET Q q 0 0 0 rg BT 292.45 287.32 Td (present ) Tj ET Q q 0 0 0 rg BT 327.67 287.32 Td (– ) Tj ET Q q 0 0 0 rg BT 339.01 287.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 371.00 287.32 Td (V) Tj ET Q q 0 0 0 rg BT 377.62 287.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 395.61 287.32 Td (President ) Tj ET Q q 0 0 0 rg BT 439.16 287.32 Td (& ) Tj ET Q q 0 0 0 rg BT 453.28 287.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 499.33 287.32 Td (Global ) Tj ET Q q 0 0 0 rg BT 532.89 287.32 Td (Product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 277.32 Td (Development ) Tj ET Q q 0 0 0 rg BT 308.37 277.32 Td (and ) Tj ET Q q 0 0 0 rg BT 325.31 277.32 Td (Supply) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 252.32 Td (Paul von ) Tj ET Q q 0 0 0 rg BT 76.23 252.32 Td (Autenried) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 242.31 Td (Senior V) Tj ET Q q 0 0 0 rg BT 72.97 242.31 Td (ice Pr) Tj ET Q q 0 0 0 rg BT 96.76 242.31 Td (esident, Chief Information ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 232.31 Td (Officer) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 222.31 Td (Member of the Leadership T) Tj ET Q q 0 0 0 rg BT 151.96 222.31 Td (eam) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 231.65 252.32 Td (56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 252.32 Td (2012 ) Tj ET Q q 0 0 0 rg BT 273.44 252.32 Td (to ) Tj ET Q q 0 0 0 rg BT 282.66 252.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 304.10 252.32 Td (– ) Tj ET Q q 0 0 0 rg BT 310.54 252.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 337.98 252.32 Td (V) Tj ET Q q 0 0 0 rg BT 344.60 252.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 357.70 252.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 398.85 252.32 Td (Enterprise ) Tj ET Q q 0 0 0 rg BT 441.38 252.32 Td (Services ) Tj ET Q q 0 0 0 rg BT 476.70 252.32 Td (and ) Tj ET Q q 0 0 0 rg BT 492.58 252.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 516.24 252.32 Td (Information ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 242.32 Td (Of) Tj ET Q q 0 0 0 rg BT 262.37 242.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.00 232.32 Td (2016 ) Tj ET Q q 0 0 0 rg BT 274.50 232.32 Td (to ) Tj ET Q q 0 0 0 rg BT 284.78 232.32 Td (present ) Tj ET Q q 0 0 0 rg BT 316.16 232.32 Td (– ) Tj ET Q q 0 0 0 rg BT 323.66 232.32 Td (Senior ) Tj ET Q q 0 0 0 rg BT 352.08 232.32 Td (V) Tj ET Q q 0 0 0 rg BT 358.70 232.32 Td (ice ) Tj ET Q q 0 0 0 rg BT 372.86 232.32 Td (President, ) Tj ET Q q 0 0 0 rg BT 415.08 232.32 Td (Chief ) Tj ET Q q 0 0 0 rg BT 439.79 232.32 Td (Information ) Tj ET Q q 0 0 0 rg BT 490.06 232.32 Td (Of) Tj ET Q q 0 0 0 rg BT 500.43 232.32 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 55 0 obj <> endobj 56 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (27) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 287.85 749.25 Td (P) Tj ET Q q 0 0 0 rg BT 293.22 749.25 Td (AR) Tj ET Q q 0 0 0 rg BT 307.31 749.25 Td (T) Tj ET Q q 0 0 0 rg BT 313.80 749.25 Td ( II) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 718.68 Td (Item 5.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 718.68 Td (MARKET) Tj ET Q q 0 0 0 rg BT 139.82 718.68 Td ( FOR ) Tj ET Q q 0 0 0 rg BT 165.75 718.68 Td (THE REGISTRANT’S COMMON ST) Tj ET Q q 0 0 0 rg BT 330.31 718.68 Td (OCK ) Tj ET Q q 0 0 0 rg BT 355.04 718.68 Td (AND OTHER ST) Tj ET Q q 0 0 0 rg BT 429.87 718.68 Td (OCKHOLDER MA) Tj ET Q q 0 0 0 rg BT 514.41 718.68 Td (TTERS.) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 693.45 Td (Market Prices) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 676.45 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 94.47 676.45 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 125.17 676.45 Td (common ) Tj ET Q q 0 0 0 rg BT 162.53 676.45 Td (stock ) Tj ET Q q 0 0 0 rg BT 186.00 676.45 Td (is ) Tj ET Q q 0 0 0 rg BT 195.03 676.45 Td (traded ) Tj ET Q q 0 0 0 rg BT 222.38 676.45 Td (on ) Tj ET Q q 0 0 0 rg BT 234.74 676.45 Td (the ) Tj ET Q q 0 0 0 rg BT 249.32 676.45 Td (New ) Tj ET Q q 0 0 0 rg BT 270.22 676.45 Td (Y) Tj ET Q q 0 0 0 rg BT 276.44 676.45 Td (ork ) Tj ET Q q 0 0 0 rg BT 292.13 676.45 Td (Stock ) Tj ET Q q 0 0 0 rg BT 317.27 676.45 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 359.06 676.45 Td (\(Symbol: ) Tj ET Q q 0 0 0 rg BT 398.64 676.45 Td (BMY\). ) Tj ET Q q 0 0 0 rg BT 429.10 676.45 Td (A) Tj ET Q q 0 0 0 rg BT 435.77 676.45 Td ( ) Tj ET Q q 0 0 0 rg BT 438.13 676.45 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 476.59 676.45 Td (summary ) Tj ET Q q 0 0 0 rg BT 516.17 676.45 Td (of ) Tj ET Q q 0 0 0 rg BT 526.86 676.45 Td (the ) Tj ET Q q 0 0 0 rg BT 541.44 676.45 Td (high ) Tj ET Q q 0 0 0 rg BT 561.58 676.45 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 664.45 Td (low ) Tj ET Q q 0 0 0 rg BT 53.50 664.45 Td (closing ) Tj ET Q q 0 0 0 rg BT 84.89 664.45 Td (market ) Tj ET Q q 0 0 0 rg BT 115.15 664.45 Td (price ) Tj ET Q q 0 0 0 rg BT 137.64 664.45 Td (is ) Tj ET Q q 0 0 0 rg BT 146.81 664.45 Td (presented ) Tj ET Q q 0 0 0 rg BT 187.62 664.45 Td (below:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 629.95 260.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 296.50 629.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 300.50 629.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 629.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 629.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 436.50 629.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 440.50 629.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 629.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 629.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 601.95 260.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 296.50 601.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 300.50 601.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 601.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 601.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 436.50 601.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 440.50 601.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 601.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 601.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 573.95 260.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 296.50 573.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 300.50 573.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 573.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 573.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 436.50 573.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 440.50 573.95 66.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 573.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 573.95 66.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 300.5 641.95 m 366.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 366.5 641.95 m 370.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 370.5 641.95 m 436.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 440.5 641.95 m 506.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 641.95 m 510.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 510.5 641.95 m 576.5 641.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 300.5 629.95 m 366.5 629.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 370.5 629.95 m 436.5 629.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 440.5 629.95 m 506.5 629.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 510.5 629.95 m 576.5 629.95 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 645.90 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 360.00 646.03 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 500.00 646.03 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 633.90 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 324.55 634.03 Td (High) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 395.40 634.03 Td (Low) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 464.55 634.03 Td (High) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 535.40 634.03 Td (Low) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 620.68 Td (Common:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 606.52 Td (First Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.00 606.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 606.52 Td (60.13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.00 606.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 606.52 Td (46.82) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.00 606.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 606.52 Td (68.35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.00 606.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 606.52 Td (58.87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 592.52 Td (Second Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 592.52 Td (57.33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 592.52 Td (51.66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 592.52 Td (74.29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 592.52 Td (64.91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 578.52 Td (Third Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 578.52 Td (63.74) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 578.52 Td (54.24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 578.52 Td (76.77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 578.52 Td (53.87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 564.52 Td (Fourth Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 564.52 Td (65.35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 564.52 Td (59.94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 564.52 Td (59.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 564.52 Td (49.23) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 536.45 Td (Holders of Common Stock) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 512.45 Td (The number of record holders of common stock at December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.13 512.45 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.13 512.45 Td ( was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 338.69 512.45 Td (41,402) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.19 512.45 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 491.45 Td (The ) Tj ET Q q 0 0 0 rg BT 54.72 491.45 Td (number ) Tj ET Q q 0 0 0 rg BT 88.44 491.45 Td (of ) Tj ET Q q 0 0 0 rg BT 99.94 491.45 Td (record ) Tj ET Q q 0 0 0 rg BT 128.65 491.45 Td (holders ) Tj ET Q q 0 0 0 rg BT 161.26 491.45 Td (is ) Tj ET Q q 0 0 0 rg BT 171.10 491.45 Td (based ) Tj ET Q q 0 0 0 rg BT 197.04 491.45 Td (upon ) Tj ET Q q 0 0 0 rg BT 220.21 491.45 Td (the ) Tj ET Q q 0 0 0 rg BT 235.60 491.45 Td (actual ) Tj ET Q q 0 0 0 rg BT 262.64 491.45 Td (number ) Tj ET Q q 0 0 0 rg BT 296.36 491.45 Td (of ) Tj ET Q q 0 0 0 rg BT 307.86 491.45 Td (holders ) Tj ET Q q 0 0 0 rg BT 340.47 491.45 Td (registered ) Tj ET Q q 0 0 0 rg BT 383.07 491.45 Td (on ) Tj ET Q q 0 0 0 rg BT 396.24 491.45 Td (our ) Tj ET Q q 0 0 0 rg BT 412.74 491.45 Td (books ) Tj ET Q q 0 0 0 rg BT 439.80 491.45 Td (at ) Tj ET Q q 0 0 0 rg BT 450.19 491.45 Td (such ) Tj ET Q q 0 0 0 rg BT 471.69 491.45 Td (date ) Tj ET Q q 0 0 0 rg BT 491.52 491.45 Td (and ) Tj ET Q q 0 0 0 rg BT 509.13 491.45 Td (does ) Tj ET Q q 0 0 0 rg BT 530.63 491.45 Td (not ) Tj ET Q q 0 0 0 rg BT 546.58 491.45 Td (include ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 479.45 Td (holders ) Tj ET Q q 0 0 0 rg BT 68.50 479.45 Td (of ) Tj ET Q q 0 0 0 rg BT 79.90 479.45 Td (shares ) Tj ET Q q 0 0 0 rg BT 107.95 479.45 Td (in ) Tj ET Q q 0 0 0 rg BT 118.79 479.45 Td (“street ) Tj ET Q q 0 0 0 rg BT 147.95 479.45 Td (names” ) Tj ET Q q 0 0 0 rg BT 181.00 479.45 Td (or ) Tj ET Q q 0 0 0 rg BT 192.39 479.45 Td (persons, ) Tj ET Q q 0 0 0 rg BT 228.51 479.45 Td (partnerships, ) Tj ET Q q 0 0 0 rg BT 282.95 479.45 Td (associations, ) Tj ET Q q 0 0 0 rg BT 336.84 479.45 Td (corporations ) Tj ET Q q 0 0 0 rg BT 389.89 479.45 Td (or ) Tj ET Q q 0 0 0 rg BT 401.28 479.45 Td (other ) Tj ET Q q 0 0 0 rg BT 424.89 479.45 Td (entities ) Tj ET Q q 0 0 0 rg BT 456.84 479.45 Td (identified ) Tj ET Q q 0 0 0 rg BT 498.22 479.45 Td (in ) Tj ET Q q 0 0 0 rg BT 509.07 479.45 Td (security ) Tj ET Q q 0 0 0 rg BT 543.79 479.45 Td (position ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 467.45 Td (listings ) Tj ET Q q 0 0 0 rg BT 67.40 467.45 Td (maintained ) Tj ET Q q 0 0 0 rg BT 114.33 467.45 Td (by ) Tj ET Q q 0 0 0 rg BT 126.83 467.45 Td (depository ) Tj ET Q q 0 0 0 rg BT 171.54 467.45 Td (trust ) Tj ET Q q 0 0 0 rg BT 191.82 467.45 Td (companies.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 441.45 Td (Dividends) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 424.45 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.05 424.45 Td (Board ) Tj ET Q q 0 0 0 rg BT 80.99 424.45 Td (of ) Tj ET Q q 0 0 0 rg BT 91.82 424.45 Td (Directors ) Tj ET Q q 0 0 0 rg BT 131.53 424.45 Td (declared ) Tj ET Q q 0 0 0 rg BT 167.89 424.45 Td (the ) Tj ET Q q 0 0 0 rg BT 182.61 424.45 Td (following ) Tj ET Q q 0 0 0 rg BT 223.99 424.45 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 262.59 424.45 Td (dividends ) Tj ET Q q 0 0 0 rg BT 303.97 424.45 Td (per ) Tj ET Q q 0 0 0 rg BT 319.24 424.45 Td (share, ) Tj ET Q q 0 0 0 rg BT 345.34 424.45 Td (which ) Tj ET Q q 0 0 0 rg BT 372.28 424.45 Td (were ) Tj ET Q q 0 0 0 rg BT 394.21 424.45 Td (paid ) Tj ET Q q 0 0 0 rg BT 413.92 424.45 Td (in ) Tj ET Q q 0 0 0 rg BT 424.20 424.45 Td (the ) Tj ET Q q 0 0 0 rg BT 438.92 424.45 Td (periods ) Tj ET Q q 0 0 0 rg BT 470.86 424.45 Td (indicated ) Tj ET Q q 0 0 0 rg BT 510.01 424.45 Td (below:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 389.95 266.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 302.50 389.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 306.50 389.95 65.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 371.50 389.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 375.50 389.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 439.50 389.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 389.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 389.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 389.95 65.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 361.95 266.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 302.50 361.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 306.50 361.95 65.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 371.50 361.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 375.50 361.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 439.50 361.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 361.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 361.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 361.95 65.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 333.95 266.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 302.50 333.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 306.50 333.95 65.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 371.50 333.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 375.50 333.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 439.50 333.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 333.95 64.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 333.95 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 333.95 65.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 306.5 401.95 m 371.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 371.5 401.95 m 375.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 401.95 m 439.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 401.95 m 507.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 401.95 m 511.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 401.95 m 576.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 306.5 389.95 m 371.5 389.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 401.95 m 439.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 389.95 m 439.5 389.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 389.95 m 507.5 389.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 401.95 m 576.5 401.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 389.95 m 576.5 389.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 389.95 m 439.5 389.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 306.5 333.95 m 371.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 333.95 m 439.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 333.95 m 507.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 333.95 m 576.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 306.5 320.95 m 371.5 320.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 306.5 318.95 m 371.5 318.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 333.95 m 439.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 320.95 m 439.5 320.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 375.5 318.95 m 439.5 318.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 333.95 m 507.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 320.95 m 507.5 320.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 318.95 m 507.5 318.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 333.95 m 576.5 333.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 320.95 m 576.5 320.95 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 318.95 m 576.5 318.95 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 405.90 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 356.70 406.03 Td (Common) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 492.95 406.03 Td (Pr) Tj ET Q q 0 0 0 rg BT 501.32 406.03 Td (eferr) Tj ET Q q 0 0 0 rg BT 518.04 406.03 Td (ed) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 393.90 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 330.50 394.03 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 399.00 394.03 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 467.00 394.03 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 535.50 394.03 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 380.52 Td (First Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.00 380.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.15 380.52 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.00 380.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.15 380.52 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.00 380.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 380.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.00 380.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 380.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 366.52 Td (Second Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.15 366.52 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.15 366.52 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 366.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 366.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 352.52 Td (Third Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.15 352.52 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.15 352.52 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 352.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 352.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 338.52 Td (Fourth Quarter) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.15 338.52 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.15 338.52 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 338.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 338.52 Td (0.50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.00 324.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.15 324.52 Td (1.56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.00 324.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.15 324.52 Td (1.52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.00 324.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 324.52 Td (2.00) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.00 324.52 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 324.52 Td (2.00) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 296.45 Td (In ) Tj ET Q q 0 0 0 rg BT 47.24 296.45 Td (December ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 91.24 296.45 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 111.24 296.45 Td (, ) Tj ET Q q 0 0 0 rg BT 116.65 296.45 Td (our ) Tj ET Q q 0 0 0 rg BT 132.89 296.45 Td (Board ) Tj ET Q q 0 0 0 rg BT 160.24 296.45 Td (of ) Tj ET Q q 0 0 0 rg BT 171.48 296.45 Td (Directors ) Tj ET Q q 0 0 0 rg BT 211.60 296.45 Td (declared ) Tj ET Q q 0 0 0 rg BT 248.38 296.45 Td (a ) Tj ET Q q 0 0 0 rg BT 255.73 296.45 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 294.73 296.45 Td (dividend ) Tj ET Q q 0 0 0 rg BT 332.64 296.45 Td (of ) Tj ET Q q 0 0 0 rg BT 343.88 296.45 Td ($0.40 ) Tj ET Q q 0 0 0 rg BT 369.29 296.45 Td (per ) Tj ET Q q 0 0 0 rg BT 384.97 296.45 Td (share ) Tj ET Q q 0 0 0 rg BT 408.98 296.45 Td (on ) Tj ET Q q 0 0 0 rg BT 421.89 296.45 Td (our ) Tj ET Q q 0 0 0 rg BT 438.13 296.45 Td (common ) Tj ET Q q 0 0 0 rg BT 476.04 296.45 Td (stock ) Tj ET Q q 0 0 0 rg BT 500.06 296.45 Td (which ) Tj ET Q q 0 0 0 rg BT 527.41 296.45 Td (was ) Tj ET Q q 0 0 0 rg BT 545.87 296.45 Td (paid ) Tj ET Q q 0 0 0 rg BT 566.00 296.45 Td (on ) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 291.38 68.12 -9.09 re f /GS0 gs q 0 0 0 rg BT 36.00 284.45 Td (February ) Tj ET Q q 0 0 0 rg BT 74.36 284.45 Td (1, ) Tj ET Q q 0 0 0 rg BT 84.12 284.45 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 104.12 284.45 Td ( ) Tj ET Q q 0 0 0 rg BT 106.39 284.45 Td (to ) Tj ET Q q 0 0 0 rg BT 116.43 284.45 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 169.23 284.45 Td (of ) Tj ET Q q 0 0 0 rg BT 179.82 284.45 Td (record ) Tj ET Q q 0 0 0 rg BT 207.62 284.45 Td (as ) Tj ET Q q 0 0 0 rg BT 218.21 284.45 Td (of ) Tj ET Q q 0 0 0 rg BT 228.80 284.45 Td (January ) Tj ET Q q 0 0 0 rg BT 262.16 284.45 Td (5, ) Tj ET Q q 0 0 0 rg BT 271.92 284.45 Td (2018. ) Tj ET Q q 0 0 0 rg BT 296.52 284.45 Td (The ) Tj ET Q q 0 0 0 rg BT 314.33 284.45 Td (Board ) Tj ET Q q 0 0 0 rg BT 341.03 284.45 Td (of ) Tj ET Q q 0 0 0 rg BT 351.63 284.45 Td (Directors ) Tj ET Q q 0 0 0 rg BT 391.09 284.45 Td (also ) Tj ET Q q 0 0 0 rg BT 409.46 284.45 Td (declared ) Tj ET Q q 0 0 0 rg BT 445.59 284.45 Td (a ) Tj ET Q q 0 0 0 rg BT 452.29 284.45 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 490.65 284.45 Td (dividend ) Tj ET Q q 0 0 0 rg BT 527.90 284.45 Td (of ) Tj ET Q q 0 0 0 rg BT 538.50 284.45 Td ($0.50 ) Tj ET Q q 0 0 0 rg BT 563.26 284.45 Td (per ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 272.45 Td (share ) Tj ET Q q 0 0 0 rg BT 59.60 272.45 Td (on ) Tj ET Q q 0 0 0 rg BT 72.10 272.45 Td (our ) Tj ET Q q 0 0 0 rg BT 87.93 272.45 Td (preferred ) Tj ET Q q 0 0 0 rg BT 127.06 272.45 Td (stock, ) Tj ET Q q 0 0 0 rg BT 153.17 272.45 Td (payable ) Tj ET Q q 0 0 0 rg BT 186.77 272.45 Td (on ) Tj ET Q q 0 0 0 rg BT 199.27 272.45 Td (March ) Tj ET Q q 0 0 0 rg BT 227.87 272.45 Td (1, ) Tj ET Q q 0 0 0 rg BT 237.87 272.45 Td (2018 ) Tj ET Q q 0 0 0 rg BT 260.37 272.45 Td (to ) Tj ET Q q 0 0 0 rg BT 270.64 272.45 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 323.68 272.45 Td (of ) Tj ET Q q 0 0 0 rg BT 334.51 272.45 Td (record ) Tj ET Q q 0 0 0 rg BT 362.55 272.45 Td (as ) Tj ET Q q 0 0 0 rg BT 373.38 272.45 Td (of ) Tj ET Q q 0 0 0 rg BT 384.21 272.45 Td (February ) Tj ET Q q 0 0 0 rg BT 422.81 272.45 Td (6, ) Tj ET Q q 0 0 0 rg BT 432.81 272.45 Td (2018.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 248.45 Td (UNREGISTERED SALES OF) Tj ET Q q 0 0 0 rg BT 166.22 248.45 Td ( EQUITY) Tj ET Q q 0 0 0 rg BT 207.80 248.45 Td ( SECURITIES ) Tj ET Q q 0 0 0 rg BT 272.83 248.45 Td (AND USE OF) Tj ET Q q 0 0 0 rg BT 332.46 248.45 Td ( PROCEEDS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 231.45 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 231.45 Td (following ) Tj ET Q q 0 0 0 rg BT 95.43 231.45 Td (table ) Tj ET Q q 0 0 0 rg BT 117.37 231.45 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 167.63 231.45 Td (the ) Tj ET Q q 0 0 0 rg BT 182.35 231.45 Td (surrenders ) Tj ET Q q 0 0 0 rg BT 226.50 231.45 Td (of ) Tj ET Q q 0 0 0 rg BT 237.33 231.45 Td (our ) Tj ET Q q 0 0 0 rg BT 253.16 231.45 Td (equity ) Tj ET Q q 0 0 0 rg BT 280.65 231.45 Td (securities ) Tj ET Q q 0 0 0 rg BT 320.92 231.45 Td (during ) Tj ET Q q 0 0 0 rg BT 349.53 231.45 Td (the ) Tj ET Q q 0 0 0 rg BT 364.24 231.45 Td (three ) Tj ET Q q 0 0 0 rg BT 386.73 231.45 Td (months ) Tj ET Q q 0 0 0 rg BT 418.68 231.45 Td (ended ) Tj ET Q q 0 0 0 rg BT 445.05 231.45 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.64 231.45 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.64 231.45 Td (:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 162.95 212.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 248.50 162.95 78.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 162.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 162.95 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 162.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 392.50 162.95 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 162.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 162.95 100.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 132.95 212.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 248.50 132.95 78.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 132.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 132.95 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 132.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 392.50 132.95 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 132.95 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 132.95 100.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 36.5 175.95000000000005 m 248.5 175.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 248.5 175.95000000000005 m 326.5 175.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 175.95000000000005 m 388.5 175.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 175.95000000000005 m 472.5 175.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 476.5 175.95000000000005 m 576.5 175.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 248.5 117.95000000000005 m 326.5 117.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 117.95000000000005 m 472.5 117.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 248.5 102.95000000000005 m 326.5 102.95000000000005 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 102.95000000000005 m 472.5 102.95000000000005 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 39.00 180.18 Td (Period) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 258.75 188.18 Td (T) Tj ET Q q 0 0 0 rg BT 263.35 188.18 Td (otal Number) Tj ET Q q 0 0 0 rg BT 306.54 188.18 Td ( of) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 252.75 180.18 Td (Shar) Tj ET Q q 0 0 0 rg BT 269.05 180.18 Td (es Pur) Tj ET Q q 0 0 0 rg BT 290.46 180.18 Td (chased) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 313.57 184.71 Td (\(a\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 335.20 196.18 Td (A) Tj ET Q q 0 0 0 rg BT 340.38 196.18 Td (verage Price) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 351.20 188.18 Td (Paid) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 338.55 180.18 Td (per) Tj ET Q q 0 0 0 rg BT 349.96 180.18 Td ( Shar) Tj ET Q q 0 0 0 rg BT 368.26 180.18 Td (e) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 371.81 184.71 Td (\(a\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 403.75 212.18 Td (T) Tj ET Q q 0 0 0 rg BT 408.35 212.18 Td (otal Number) Tj ET Q q 0 0 0 rg BT 451.54 212.18 Td ( of  ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 420.50 204.18 Td (Shar) Tj ET Q q 0 0 0 rg BT 436.80 204.18 Td (es) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 396.60 196.18 Td (Pur) Tj ET Q q 0 0 0 rg BT 409.34 196.18 Td (chased as Part of) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 397.65 188.18 Td (Publicly ) Tj ET Q q 0 0 0 rg BT 427.21 188.18 Td (Announced ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 411.20 180.18 Td (Pr) Tj ET Q q 0 0 0 rg BT 419.49 180.18 Td (ograms) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 444.82 184.71 Td (\(b\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 481.00 204.18 Td (Appr) Tj ET Q q 0 0 0 rg BT 499.08 204.18 Td (oximate Dollar) Tj ET Q q 0 0 0 rg BT 549.81 204.18 Td ( ) Tj ET Q q 0 0 0 rg BT 551.67 204.18 Td (V) Tj ET Q q 0 0 0 rg BT 556.71 204.18 Td (alue) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 481.65 196.18 Td (of Shar) Tj ET Q q 0 0 0 rg BT 506.62 196.18 Td (es that May ) Tj ET Q q 0 0 0 rg BT 548.31 196.18 Td (Y) Tj ET Q q 0 0 0 rg BT 553.20 196.18 Td (et Be) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 489.90 188.18 Td (Pur) Tj ET Q q 0 0 0 rg BT 502.64 188.18 Td (chased Under) Tj ET Q q 0 0 0 rg BT 549.39 188.18 Td ( the) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 505.20 180.18 Td (Pr) Tj ET Q q 0 0 0 rg BT 513.49 180.18 Td (ograms) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 538.82 184.71 Td (\(b\)) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 167.20 Td (Dollars in Millions, Except Per Share Data) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 251.00 167.20 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 333.00 167.20 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 395.00 167.20 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 479.00 167.20 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 153.52 Td (October 1 to 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.65 152.62 Td (1,498,834) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.00 152.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.15 152.62 Td (63.02) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.65 152.62 Td (1,491,785) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.00 152.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 152.62 Td (1,818) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 138.52 Td (November 1 to 30, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.65 137.62 Td (1,444,201) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.00 137.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.15 137.62 Td (61.85) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.65 137.62 Td (1,434,937) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.00 137.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 137.62 Td (1,729) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 123.52 Td (December 1 to 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.65 122.62 Td (1,121,513) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.00 122.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.15 122.62 Td (62.1) Tj ET Q q 0 0 0 rg BT 379.65 122.62 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.65 122.62 Td (1,099,102) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.00 122.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 122.62 Td (1,661) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 108.52 Td (Three months ended December 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.65 107.62 Td (4,064,548) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.65 107.62 Td (4,025,824) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 81.85 Td (\(a\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 81.85 Td (Includes ) Tj ET Q q 0 0 0 rg BT 89.95 81.85 Td (shares ) Tj ET Q q 0 0 0 rg BT 111.44 81.85 Td (repurchased ) Tj ET Q q 0 0 0 rg BT 151.59 81.85 Td (as ) Tj ET Q q 0 0 0 rg BT 159.75 81.85 Td (part ) Tj ET Q q 0 0 0 rg BT 173.69 81.85 Td (of ) Tj ET Q q 0 0 0 rg BT 181.85 81.85 Td (publicly ) Tj ET Q q 0 0 0 rg BT 209.57 81.85 Td (announced ) Tj ET Q q 0 0 0 rg BT 245.72 81.85 Td (programs ) Tj ET Q q 0 0 0 rg BT 277.44 81.85 Td (and ) Tj ET Q q 0 0 0 rg BT 290.49 81.85 Td (shares ) Tj ET Q q 0 0 0 rg BT 311.98 81.85 Td (of ) Tj ET Q q 0 0 0 rg BT 320.15 81.85 Td (common ) Tj ET Q q 0 0 0 rg BT 349.64 81.85 Td (stock ) Tj ET Q q 0 0 0 rg BT 368.03 81.85 Td (surrendered ) Tj ET Q q 0 0 0 rg BT 407.29 81.85 Td (to ) Tj ET Q q 0 0 0 rg BT 415.01 81.85 Td (the ) Tj ET Q q 0 0 0 rg BT 426.28 81.85 Td (Company ) Tj ET Q q 0 0 0 rg BT 458.89 81.85 Td (to ) Tj ET Q q 0 0 0 rg BT 466.62 81.85 Td (satisfy ) Tj ET Q q 0 0 0 rg BT 489.00 81.85 Td (tax ) Tj ET Q q 0 0 0 rg BT 500.28 81.85 Td (withholding ) Tj ET Q q 0 0 0 rg BT 540.44 81.85 Td (obligations ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 72.25 Td (in ) Tj ET Q q 0 0 0 rg BT 69.57 72.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 106.67 72.25 Td (with ) Tj ET Q q 0 0 0 rg BT 122.89 72.25 Td (the ) Tj ET Q q 0 0 0 rg BT 134.67 72.25 Td (vesting ) Tj ET Q q 0 0 0 rg BT 159.78 72.25 Td (of ) Tj ET Q q 0 0 0 rg BT 168.44 72.25 Td (awards ) Tj ET Q q 0 0 0 rg BT 193.10 72.25 Td (under ) Tj ET Q q 0 0 0 rg BT 213.31 72.25 Td (our ) Tj ET Q q 0 0 0 rg BT 225.97 72.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 259.52 72.25 Td (incentive ) Tj ET Q q 0 0 0 rg BT 290.84 72.25 Td (program.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 62.65 Td (\(b\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 62.65 Td (In ) Tj ET Q q 0 0 0 rg BT 69.57 62.65 Td (May ) Tj ET Q q 0 0 0 rg BT 85.78 62.65 Td (2010, ) Tj ET Q q 0 0 0 rg BT 105.33 62.65 Td (the ) Tj ET Q q 0 0 0 rg BT 116.66 62.65 Td (Board ) Tj ET Q q 0 0 0 rg BT 137.76 62.65 Td (of ) Tj ET Q q 0 0 0 rg BT 145.98 62.65 Td (Directors ) Tj ET Q q 0 0 0 rg BT 177.29 62.65 Td (authorized ) Tj ET Q q 0 0 0 rg BT 212.61 62.65 Td (the ) Tj ET Q q 0 0 0 rg BT 223.93 62.65 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 260.13 62.65 Td (of ) Tj ET Q q 0 0 0 rg BT 268.35 62.65 Td (up ) Tj ET Q q 0 0 0 rg BT 277.90 62.65 Td (to ) Tj ET Q q 0 0 0 rg BT 285.67 62.65 Td ($3.0 ) Tj ET Q q 0 0 0 rg BT 301.22 62.65 Td (billion ) Tj ET Q q 0 0 0 rg BT 323.67 62.65 Td (of ) Tj ET Q q 0 0 0 rg BT 331.88 62.65 Td (common ) Tj ET Q q 0 0 0 rg BT 361.43 62.65 Td (stock ) Tj ET Q q 0 0 0 rg BT 379.87 62.65 Td (and ) Tj ET Q q 0 0 0 rg BT 392.97 62.65 Td (in ) Tj ET Q q 0 0 0 rg BT 400.74 62.65 Td (June ) Tj ET Q q 0 0 0 rg BT 416.96 62.65 Td (2012 ) Tj ET Q q 0 0 0 rg BT 434.51 62.65 Td (increased ) Tj ET Q q 0 0 0 rg BT 466.27 62.65 Td (its ) Tj ET Q q 0 0 0 rg BT 475.38 62.65 Td (authorization ) Tj ET Q q 0 0 0 rg BT 519.14 62.65 Td (for ) Tj ET Q q 0 0 0 rg BT 530.02 62.65 Td (the ) Tj ET Q q 0 0 0 rg BT 541.34 62.65 Td (repurchase ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 53.05 Td (of ) Tj ET Q q 0 0 0 rg BT 70.08 53.05 Td (common ) Tj ET Q q 0 0 0 rg BT 100.15 53.05 Td (stock ) Tj ET Q q 0 0 0 rg BT 119.11 53.05 Td (by ) Tj ET Q q 0 0 0 rg BT 129.18 53.05 Td (an ) Tj ET Q q 0 0 0 rg BT 138.80 53.05 Td (additional ) Tj ET Q q 0 0 0 rg BT 172.86 53.05 Td ($3.0 ) Tj ET Q q 0 0 0 rg BT 188.93 53.05 Td (billion. ) Tj ET Q q 0 0 0 rg BT 213.89 53.05 Td (In ) Tj ET Q q 0 0 0 rg BT 222.63 53.05 Td (October ) Tj ET Q q 0 0 0 rg BT 250.46 53.05 Td (2016, ) Tj ET Q q 0 0 0 rg BT 270.53 53.05 Td (the ) Tj ET Q q 0 0 0 rg BT 282.38 53.05 Td (Board ) Tj ET Q q 0 0 0 rg BT 304.00 53.05 Td (of ) Tj ET Q q 0 0 0 rg BT 312.73 53.05 Td (Directors ) Tj ET Q q 0 0 0 rg BT 344.57 53.05 Td (approved ) Tj ET Q q 0 0 0 rg BT 376.40 53.05 Td (a ) Tj ET Q q 0 0 0 rg BT 382.03 53.05 Td (new ) Tj ET Q q 0 0 0 rg BT 397.42 53.05 Td (share ) Tj ET Q q 0 0 0 rg BT 416.37 53.05 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 453.09 53.05 Td (program ) Tj ET Q q 0 0 0 rg BT 482.26 53.05 Td (authorizing ) Tj ET Q q 0 0 0 rg BT 520.76 53.05 Td (the ) Tj ET Q q 0 0 0 rg BT 532.61 53.05 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 569.32 53.05 Td (of ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 43.45 Td (an ) Tj ET Q q 0 0 0 rg BT 70.90 43.45 Td (additional ) Tj ET Q q 0 0 0 rg BT 104.89 43.45 Td ($3.0 ) Tj ET Q q 0 0 0 rg BT 120.89 43.45 Td (billion ) Tj ET Q q 0 0 0 rg BT 143.78 43.45 Td (of ) Tj ET Q q 0 0 0 rg BT 152.45 43.45 Td (common ) Tj ET Q q 0 0 0 rg BT 182.44 43.45 Td (stock. ) Tj ET Q q 0 0 0 rg BT 203.19 43.45 Td (The ) Tj ET Q q 0 0 0 rg BT 217.62 43.45 Td (stock ) Tj ET Q q 0 0 0 rg BT 236.51 43.45 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 273.15 43.45 Td (program ) Tj ET Q q 0 0 0 rg BT 302.26 43.45 Td (does ) Tj ET Q q 0 0 0 rg BT 318.92 43.45 Td (not ) Tj ET Q q 0 0 0 rg BT 331.14 43.45 Td (have ) Tj ET Q q 0 0 0 rg BT 348.24 43.45 Td (an ) Tj ET Q q 0 0 0 rg BT 357.80 43.45 Td (expiration ) Tj ET Q q 0 0 0 rg BT 392.23 43.45 Td (date. ) Tj ET Q endstream endobj 57 0 obj <> endobj 58 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (28) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 746.23 Td (Item 6.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 746.23 Td (SELECTED FINANCIAL) Tj ET Q q 0 0 0 rg BT 206.97 746.23 Td ( DA) Tj ET Q q 0 0 0 rg BT 223.17 746.23 Td (T) Tj ET Q q 0 0 0 rg BT 229.10 746.23 Td (A.) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 721.00 Td (Five ) Tj ET Q q 0 0 0 rg BT 56.45 721.00 Td (Y) Tj ET Q q 0 0 0 rg BT 62.57 721.00 Td (ear) Tj ET Q q 0 0 0 rg BT 76.26 721.00 Td ( Financial Summary) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 697.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 697.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 697.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 697.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 697.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 697.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 697.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 697.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 697.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 697.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 697.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 671.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 671.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 671.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 671.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 671.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 671.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 671.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 671.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 671.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 671.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 671.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 645.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 645.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 645.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 645.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 645.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 645.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 645.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 645.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 645.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 645.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 645.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 619.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 619.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 619.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 619.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 619.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 619.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 619.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 619.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 619.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 619.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 619.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 593.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 593.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 593.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 593.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 593.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 593.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 593.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 593.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 593.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 593.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 593.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 567.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 567.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 567.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 567.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 567.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 567.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 567.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 567.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 567.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 567.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 567.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 541.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 541.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 541.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 541.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 541.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 541.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 541.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 541.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 541.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 541.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 541.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 515.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 515.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 515.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 515.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 515.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 515.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 515.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 515.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 515.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 515.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 515.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 489.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 489.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 489.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 489.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 489.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 489.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 489.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 489.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 489.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 489.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 489.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 463.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 463.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 463.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 463.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 463.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 463.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 463.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 463.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 463.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 463.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 463.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 437.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 437.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 437.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 437.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 437.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 437.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 437.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 437.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 437.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 437.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 437.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 411.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 411.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 411.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 411.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 411.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 411.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 411.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 411.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 411.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 411.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 411.50 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 385.50 249.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 385.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 289.50 385.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 385.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 347.50 385.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 385.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 385.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 385.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 385.50 54.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 385.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 385.50 55.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 289.5 697.5 m 343.5 697.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 347.5 697.5 m 401.5 697.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 405.5 697.5 m 459.5 697.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 463.5 697.5 m 517.5 697.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 697.5 m 576.5 697.5 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 701.75 Td (Amounts in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 308.00 701.73 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 366.00 701.73 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 424.00 701.73 Td (2015) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 482.00 701.73 Td (2014) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 540.50 701.73 Td (2013) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 688.23 Td (Income Statement Data:) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 142.86 692.76 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 675.07 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 675.07 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 675.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.15 675.07 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 675.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.15 675.07 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 675.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.15 675.07 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 675.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 675.07 Td (15,879) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 675.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 675.07 Td (16,385) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 649.07 Td (Net Earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 324.65 649.07 Td (975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 649.07 Td (4,507) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 649.07 Td (1,631) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 649.07 Td (2,029) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 649.07 Td (2,580) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 636.07 Td (Net Earnings/\(Loss\) ) Tj ET Q q 0 0 0 rg BT 122.04 636.07 Td (Attributable to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 623.07 Td (Noncontrolling Interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 326.30 623.12 Td (\(32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.65 623.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.65 623.07 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 623.07 Td (66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.65 623.07 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 623.07 Td (17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 610.07 Td (BMS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 610.07 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 610.07 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 610.07 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 610.07 Td (2,004) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 610.07 Td (2,563) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 584.07 Td (Net Earnings per Common Share ) Tj ET Q q 0 0 0 rg BT 173.97 584.07 Td (Attributable to BMS:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 571.07 Td (Basic) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 571.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.15 571.07 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 571.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 380.15 571.07 Td (2.67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 571.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.15 571.07 Td (0.94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 571.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.15 571.07 Td (1.21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 571.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 571.07 Td (1.56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 558.07 Td (Diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 558.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.15 558.07 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 558.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 380.15 558.07 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 558.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.15 558.07 Td (0.93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 558.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.15 558.07 Td (1.20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 558.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 558.07 Td (1.54) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 532.07 Td (A) Tj ET Q q 0 0 0 rg BT 45.85 532.07 Td (verage common shares outstanding:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 519.07 Td (Basic) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 519.07 Td (1,645) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 519.07 Td (1,671) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 519.07 Td (1,667) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 519.07 Td (1,657) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 519.07 Td (1,644) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 506.07 Td (Diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 506.07 Td (1,652) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 506.07 Td (1,680) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 506.07 Td (1,679) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 506.07 Td (1,670) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 506.07 Td (1,662) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 480.07 Td (Cash dividends paid on BMS common and preferred stock) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 480.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 480.07 Td (2,577) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 480.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 480.07 Td (2,547) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 480.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 480.07 Td (2,477) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 480.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 480.07 Td (2,398) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 480.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 480.07 Td (2,309) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 454.07 Td (Cash dividends declared per common share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 454.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.15 454.07 Td (1.57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 454.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 380.15 454.07 Td (1.53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 454.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.15 454.07 Td (1.49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 454.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.15 454.07 Td (1.45) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 454.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 454.07 Td (1.41) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 428.23 Td (Financial Position Data at December) Tj ET Q q 0 0 0 rg BT 195.46 428.23 Td ( 31:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 415.07 Td (Cash and cash equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.00 415.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 415.07 Td (5,421) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.00 415.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 415.07 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.00 415.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 415.07 Td (2,385) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 415.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 415.07 Td (5,571) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 415.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 415.07 Td (3,586) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 402.07 Td (Marketable securities) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 124.80 406.60 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 402.07 Td (3,871) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 402.07 Td (4,832) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 402.07 Td (6,545) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 402.07 Td (6,272) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 402.07 Td (4,686) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 389.07 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 389.07 Td (otal ) Tj ET Q q 0 0 0 rg BT 61.63 389.07 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.15 389.07 Td (33,551) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.15 389.07 Td (33,707) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.15 389.07 Td (31,748) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 389.07 Td (33,749) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 389.07 Td (38,592) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 376.07 Td (Long-term debt) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 101.48 380.60 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.15 376.07 Td (6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.15 376.07 Td (6,465) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.15 376.07 Td (6,550) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 376.07 Td (7,242) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 376.07 Td (7,981) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 363.07 Td (Equity) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.15 363.07 Td (1) Tj ET Q q 0 0 0 rg BT 317.15 363.07 Td (1,847) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.15 363.07 Td (16,347) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.15 363.07 Td (14,424) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 363.07 Td (14,983) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 363.07 Td (15,236) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 340.80 Td (\(a\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 340.80 Td (For ) Tj ET Q q 0 0 0 rg BT 74.39 340.80 Td (a ) Tj ET Q q 0 0 0 rg BT 79.88 340.80 Td (discussion ) Tj ET Q q 0 0 0 rg BT 115.14 340.80 Td (of ) Tj ET Q q 0 0 0 rg BT 123.74 340.80 Td (items ) Tj ET Q q 0 0 0 rg BT 143.00 340.80 Td (that ) Tj ET Q q 0 0 0 rg BT 156.93 340.80 Td (af) Tj ET Q q 0 0 0 rg BT 163.00 340.80 Td (fected ) Tj ET Q q 0 0 0 rg BT 184.47 340.80 Td (the ) Tj ET Q q 0 0 0 rg BT 196.18 340.80 Td (comparability ) Tj ET Q q 0 0 0 rg BT 242.54 340.80 Td (of ) Tj ET Q q 0 0 0 rg BT 251.14 340.80 Td (results ) Tj ET Q q 0 0 0 rg BT 273.95 340.80 Td (for ) Tj ET Q q 0 0 0 rg BT 285.21 340.80 Td (the ) Tj ET Q q 0 0 0 rg BT 296.92 340.80 Td (years ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 315.73 340.80 Td (2017) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 331.73 340.80 Td (, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 335.66 340.80 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 351.66 340.80 Td ( ) Tj ET Q q 0 0 0 rg BT 353.59 340.80 Td (and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 367.07 340.80 Td (2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 383.07 340.80 Td (, ) Tj ET Q q 0 0 0 rg BT 387.01 340.80 Td (refer ) Tj ET Q q 0 0 0 rg BT 404.03 340.80 Td (to ) Tj ET Q q 0 0 0 rg BT 412.19 340.80 Td (“Item ) Tj ET Q q 0 0 0 rg BT 432.33 340.80 Td (7. ) Tj ET Q q 0 0 0 rg BT 440.26 340.80 Td (Management’) Tj ET Q q 0 0 0 rg BT 484.24 340.80 Td (s ) Tj ET Q q 0 0 0 rg BT 489.29 340.80 Td (Discussion ) Tj ET Q q 0 0 0 rg BT 526.33 340.80 Td (and ) Tj ET Q q 0 0 0 rg BT 539.39 340.80 Td (Analysis ) Tj ET Q q 0 0 0 rg BT 569.32 340.80 Td (of ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 331.20 Td (Financial ) Tj ET Q q 0 0 0 rg BT 93.12 331.20 Td (Condition ) Tj ET Q q 0 0 0 rg BT 127.12 331.20 Td (and ) Tj ET Q q 0 0 0 rg BT 140.67 331.20 Td (Results ) Tj ET Q q 0 0 0 rg BT 166.23 331.20 Td (of ) Tj ET Q q 0 0 0 rg BT 174.90 331.20 Td (Operations—Non-GAAP) Tj ET Q q 0 0 0 rg BT 255.92 331.20 Td ( ) Tj ET Q q 0 0 0 rg BT 257.92 331.20 Td (Financial ) Tj ET Q q 0 0 0 rg BT 289.69 331.20 Td (Measures.”) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 321.60 Td (\(b\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 321.60 Td (Includes ) Tj ET Q q 0 0 0 rg BT 90.45 321.60 Td (current ) Tj ET Q q 0 0 0 rg BT 115.10 321.60 Td (and ) Tj ET Q q 0 0 0 rg BT 128.65 321.60 Td (non-current ) Tj ET Q q 0 0 0 rg BT 167.97 321.60 Td (portion.) Tj ET Q endstream endobj 59 0 obj <> endobj 60 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (29) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Item 7.        MANAGEMENT’S ) Tj ET Q q 0 0 0 rg BT 178.20 749.25 Td (DISCUSSION ) Tj ET Q q 0 0 0 rg BT 245.38 749.25 Td (AND ) Tj ET Q q 0 0 0 rg BT 273.10 749.25 Td (ANAL) Tj ET Q q 0 0 0 rg BT 300.52 749.25 Td (YSIS ) Tj ET Q q 0 0 0 rg BT 330.52 749.25 Td (OF) Tj ET Q q 0 0 0 rg BT 344.03 749.25 Td ( ) Tj ET Q q 0 0 0 rg BT 351.80 749.25 Td (FINANCIAL) Tj ET Q q 0 0 0 rg BT 407.92 749.25 Td ( ) Tj ET Q q 0 0 0 rg BT 415.68 749.25 Td (CONDITION ) Tj ET Q q 0 0 0 rg BT 480.63 749.25 Td (AND ) Tj ET Q q 0 0 0 rg BT 510.06 749.25 Td (RESUL) Tj ET Q q 0 0 0 rg BT 542.49 749.25 Td (TS ) Tj ET Q q 0 0 0 rg BT 562.48 749.25 Td (OF) Tj ET Q q 0 0 0 rg BT 576.00 749.25 Td ( ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (OPERA) Tj ET Q q 0 0 0 rg BT 70.26 737.25 Td (TIONS.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 715.65 Td (EXECUTIVE SUMMAR) Tj ET Q q 0 0 0 rg BT 143.71 715.65 Td (Y) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 694.05 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 95.46 694.05 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 127.15 694.05 Td (Company ) Tj ET Q q 0 0 0 rg BT 169.38 694.05 Td (is ) Tj ET Q q 0 0 0 rg BT 179.40 694.05 Td (a ) Tj ET Q q 0 0 0 rg BT 187.19 694.05 Td (global ) Tj ET Q q 0 0 0 rg BT 215.53 694.05 Td (specialty ) Tj ET Q q 0 0 0 rg BT 254.42 694.05 Td (biopharmaceutical ) Tj ET Q q 0 0 0 rg BT 331.62 694.05 Td (company ) Tj ET Q q 0 0 0 rg BT 371.63 694.05 Td (whose ) Tj ET Q q 0 0 0 rg BT 400.53 694.05 Td (mission ) Tj ET Q q 0 0 0 rg BT 434.99 694.05 Td (is ) Tj ET Q q 0 0 0 rg BT 445.01 694.05 Td (to ) Tj ET Q q 0 0 0 rg BT 456.14 694.05 Td (discover) Tj ET Q q 0 0 0 rg BT 489.62 694.05 Td (, ) Tj ET Q q 0 0 0 rg BT 495.46 694.05 Td (develop ) Tj ET Q q 0 0 0 rg BT 530.47 694.05 Td (and ) Tj ET Q q 0 0 0 rg BT 548.25 694.05 Td (deliver ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 682.05 Td (innovative ) Tj ET Q q 0 0 0 rg BT 80.36 682.05 Td (medicines ) Tj ET Q q 0 0 0 rg BT 123.05 682.05 Td (that ) Tj ET Q q 0 0 0 rg BT 140.19 682.05 Td (help ) Tj ET Q q 0 0 0 rg BT 159.56 682.05 Td (patients ) Tj ET Q q 0 0 0 rg BT 192.81 682.05 Td (prevail ) Tj ET Q q 0 0 0 rg BT 222.72 682.05 Td (over ) Tj ET Q q 0 0 0 rg BT 242.63 682.05 Td (serious ) Tj ET Q q 0 0 0 rg BT 273.11 682.05 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 310.53 682.05 Td (Refer ) Tj ET Q q 0 0 0 rg BT 334.88 682.05 Td (to ) Tj ET Q q 0 0 0 rg BT 344.81 682.05 Td (the ) Tj ET Q q 0 0 0 rg BT 359.17 682.05 Td (Summary ) Tj ET Q q 0 0 0 rg BT 400.21 682.05 Td (of ) Tj ET Q q 0 0 0 rg BT 410.21 682.05 Td (Abbreviated ) Tj ET Q q 0 0 0 rg BT 461.63 682.05 Td (T) Tj ET Q q 0 0 0 rg BT 467.04 682.05 Td (erms ) Tj ET Q q 0 0 0 rg BT 488.62 682.05 Td (at ) Tj ET Q q 0 0 0 rg BT 497.99 682.05 Td (the ) Tj ET Q q 0 0 0 rg BT 512.35 682.05 Td (end ) Tj ET Q q 0 0 0 rg BT 528.94 682.05 Td (of ) Tj ET Q q 0 0 0 rg BT 539.41 682.05 Td (this ) Tj ET Q q 0 0 0 rg BT 556.01 682.05 Td (2017 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 670.05 Td (Form ) Tj ET Q q 0 0 0 rg BT 60.17 670.05 Td (10-K ) Tj ET Q q 0 0 0 rg BT 83.22 670.05 Td (for ) Tj ET Q q 0 0 0 rg BT 97.38 670.05 Td (terms ) Tj ET Q q 0 0 0 rg BT 122.10 670.05 Td (used ) Tj ET Q q 0 0 0 rg BT 142.93 670.05 Td (throughout ) Tj ET Q q 0 0 0 rg BT 189.32 670.05 Td (the ) Tj ET Q q 0 0 0 rg BT 204.03 670.05 Td (document.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 646.05 Td (In ) Tj ET Q q 0 0 0 rg BT 47.23 646.05 Td (2017, ) Tj ET Q q 0 0 0 rg BT 72.62 646.05 Td (we ) Tj ET Q q 0 0 0 rg BT 87.18 646.05 Td (received ) Tj ET Q q 0 0 0 rg BT 123.93 646.05 Td (15 ) Tj ET Q q 0 0 0 rg BT 136.83 646.05 Td (approvals ) Tj ET Q q 0 0 0 rg BT 178.60 646.05 Td (for ) Tj ET Q q 0 0 0 rg BT 193.16 646.05 Td (new ) Tj ET Q q 0 0 0 rg BT 212.71 646.05 Td (medicines ) Tj ET Q q 0 0 0 rg BT 256.15 646.05 Td (and ) Tj ET Q q 0 0 0 rg BT 273.49 646.05 Td (additional ) Tj ET Q q 0 0 0 rg BT 316.37 646.05 Td (indications ) Tj ET Q q 0 0 0 rg BT 363.15 646.05 Td (and ) Tj ET Q q 0 0 0 rg BT 380.48 646.05 Td (formulations ) Tj ET Q q 0 0 0 rg BT 434.48 646.05 Td (of ) Tj ET Q q 0 0 0 rg BT 445.71 646.05 Td (currently ) Tj ET Q q 0 0 0 rg BT 484.70 646.05 Td (marketed ) Tj ET Q q 0 0 0 rg BT 524.79 646.05 Td (medicines ) Tj ET Q q 0 0 0 rg BT 568.23 646.05 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 634.05 Td (major ) Tj ET Q q 0 0 0 rg BT 61.78 634.05 Td (markets ) Tj ET Q q 0 0 0 rg BT 95.89 634.05 Td (\(the ) Tj ET Q q 0 0 0 rg BT 113.89 634.05 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 136.62 634.05 Td (EU, ) Tj ET Q q 0 0 0 rg BT 154.90 634.05 Td (Japan ) Tj ET Q q 0 0 0 rg BT 180.13 634.05 Td (and ) Tj ET Q q 0 0 0 rg BT 197.02 634.05 Td (China\) ) Tj ET Q q 0 0 0 rg BT 226.69 634.05 Td (including ) Tj ET Q q 0 0 0 rg BT 266.91 634.05 Td (multiple ) Tj ET Q q 0 0 0 rg BT 302.69 634.05 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 346.24 634.05 Td (milestone ) Tj ET Q q 0 0 0 rg BT 387.58 634.05 Td (achievements ) Tj ET Q q 0 0 0 rg BT 444.45 634.05 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 458.56 634.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.00 634.05 Td (. ) Tj ET Q q 0 0 0 rg BT 492.82 634.05 Td (W) Tj ET Q q 0 0 0 rg BT 501.46 634.05 Td (e ) Tj ET Q q 0 0 0 rg BT 508.35 634.05 Td (are ) Tj ET Q q 0 0 0 rg BT 523.01 634.05 Td (committed ) Tj ET Q q 0 0 0 rg BT 568.23 634.05 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 622.05 Td (investigating ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 89.81 622.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 119.25 622.05 Td ( ) Tj ET Q q 0 0 0 rg BT 121.40 622.05 Td (alone ) Tj ET Q q 0 0 0 rg BT 145.21 622.05 Td (and ) Tj ET Q q 0 0 0 rg BT 161.80 622.05 Td (in ) Tj ET Q q 0 0 0 rg BT 171.73 622.05 Td (combination ) Tj ET Q q 0 0 0 rg BT 223.88 622.05 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 243.81 622.05 Td (Y) Tj ET Q q 0 0 0 rg BT 248.45 622.05 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 270.66 622.05 Td ( ) Tj ET Q q 0 0 0 rg BT 272.81 622.05 Td (and ) Tj ET Q q 0 0 0 rg BT 289.40 622.05 Td (other ) Tj ET Q q 0 0 0 rg BT 312.10 622.05 Td (anti-cancer ) Tj ET Q q 0 0 0 rg BT 358.66 622.05 Td (agents ) Tj ET Q q 0 0 0 rg BT 386.36 622.05 Td (for ) Tj ET Q q 0 0 0 rg BT 400.17 622.05 Td (a ) Tj ET Q q 0 0 0 rg BT 406.76 622.05 Td (wide ) Tj ET Q q 0 0 0 rg BT 428.35 622.05 Td (array ) Tj ET Q q 0 0 0 rg BT 451.04 622.05 Td (of ) Tj ET Q q 0 0 0 rg BT 461.53 622.05 Td (tumor ) Tj ET Q q 0 0 0 rg BT 487.56 622.05 Td (types, ) Tj ET Q q 0 0 0 rg BT 513.33 622.05 Td (including ) Tj ET Q q 0 0 0 rg BT 553.25 622.05 Td (broad ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 610.05 Td (programs ) Tj ET Q q 0 0 0 rg BT 76.29 610.05 Td (in ) Tj ET Q q 0 0 0 rg BT 86.59 610.05 Td (lung, ) Tj ET Q q 0 0 0 rg BT 109.40 610.05 Td (head ) Tj ET Q q 0 0 0 rg BT 130.80 610.05 Td (& ) Tj ET Q q 0 0 0 rg BT 141.10 610.05 Td (neck, ) Tj ET Q q 0 0 0 rg BT 165.00 610.05 Td (liver) Tj ET Q q 0 0 0 rg BT 182.92 610.05 Td (, ) Tj ET Q q 0 0 0 rg BT 187.95 610.05 Td (kidney) Tj ET Q q 0 0 0 rg BT 214.51 610.05 Td (, ) Tj ET Q q 0 0 0 rg BT 219.54 610.05 Td (bladder ) Tj ET Q q 0 0 0 rg BT 252.05 610.05 Td (and ) Tj ET Q q 0 0 0 rg BT 269.01 610.05 Td (gastric. ) Tj ET Q q 0 0 0 rg BT 300.50 610.05 Td (W) Tj ET Q q 0 0 0 rg BT 309.14 610.05 Td (e ) Tj ET Q q 0 0 0 rg BT 316.10 610.05 Td (continue ) Tj ET Q q 0 0 0 rg BT 353.06 610.05 Td (to ) Tj ET Q q 0 0 0 rg BT 363.36 610.05 Td (believe ) Tj ET Q q 0 0 0 rg BT 394.76 610.05 Td (that ) Tj ET Q q 0 0 0 rg BT 412.28 610.05 Td (the ) Tj ET Q q 0 0 0 rg BT 427.02 610.05 Td (breadth ) Tj ET Q q 0 0 0 rg BT 459.53 610.05 Td (and ) Tj ET Q q 0 0 0 rg BT 476.49 610.05 Td (depth ) Tj ET Q q 0 0 0 rg BT 501.23 610.05 Td (of ) Tj ET Q q 0 0 0 rg BT 512.08 610.05 Td (our ) Tj ET Q q 0 0 0 rg BT 527.93 610.05 Td (IO ) Tj ET Q q 0 0 0 rg BT 541.01 610.05 Td (portfolio ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 598.05 Td (positions ) Tj ET Q q 0 0 0 rg BT 74.41 598.05 Td (us ) Tj ET Q q 0 0 0 rg BT 85.60 598.05 Td (well ) Tj ET Q q 0 0 0 rg BT 105.11 598.05 Td (for ) Tj ET Q q 0 0 0 rg BT 119.06 598.05 Td (the ) Tj ET Q q 0 0 0 rg BT 133.57 598.05 Td (future. ) Tj ET Q q 0 0 0 rg BT 162.08 598.05 Td (W) Tj ET Q q 0 0 0 rg BT 170.72 598.05 Td (e ) Tj ET Q q 0 0 0 rg BT 177.45 598.05 Td (have ) Tj ET Q q 0 0 0 rg BT 198.62 598.05 Td (17 ) Tj ET Q q 0 0 0 rg BT 210.91 598.05 Td (new ) Tj ET Q q 0 0 0 rg BT 229.87 598.05 Td (IO ) Tj ET Q q 0 0 0 rg BT 242.71 598.05 Td (compounds ) Tj ET Q q 0 0 0 rg BT 291.12 598.05 Td (in ) Tj ET Q q 0 0 0 rg BT 301.19 598.05 Td (clinical ) Tj ET Q q 0 0 0 rg BT 332.91 598.05 Td (development ) Tj ET Q q 0 0 0 rg BT 386.85 598.05 Td (and ) Tj ET Q q 0 0 0 rg BT 403.59 598.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 433.66 598.05 Td (across ) Tj ET Q q 0 0 0 rg BT 460.94 598.05 Td (more ) Tj ET Q q 0 0 0 rg BT 483.78 598.05 Td (than ) Tj ET Q q 0 0 0 rg BT 503.29 598.05 Td (35 ) Tj ET Q q 0 0 0 rg BT 515.59 598.05 Td (dif) Tj ET Q q 0 0 0 rg BT 526.52 598.05 Td (ferent ) Tj ET Q q 0 0 0 rg BT 552.13 598.05 Td (tumor ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 586.05 Td (types. ) Tj ET Q q 0 0 0 rg BT 62.30 586.05 Td (In ) Tj ET Q q 0 0 0 rg BT 73.31 586.05 Td (addition, ) Tj ET Q q 0 0 0 rg BT 111.27 586.05 Td (we ) Tj ET Q q 0 0 0 rg BT 125.62 586.05 Td (advanced ) Tj ET Q q 0 0 0 rg BT 166.06 586.05 Td (certain ) Tj ET Q q 0 0 0 rg BT 195.95 586.05 Td (other ) Tj ET Q q 0 0 0 rg BT 219.18 586.05 Td (non-IO ) Tj ET Q q 0 0 0 rg BT 250.75 586.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 275.11 586.05 Td (programs ) Tj ET Q q 0 0 0 rg BT 315.57 586.05 Td (in ) Tj ET Q q 0 0 0 rg BT 326.03 586.05 Td (our ) Tj ET Q q 0 0 0 rg BT 342.05 586.05 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 379.45 586.05 Td (including ) Tj ET Q q 0 0 0 rg BT 419.91 586.05 Td (FGF21 ) Tj ET Q q 0 0 0 rg BT 450.94 586.05 Td (for ) Tj ET Q q 0 0 0 rg BT 465.29 586.05 Td (the ) Tj ET Q q 0 0 0 rg BT 480.19 586.05 Td (treatment ) Tj ET Q q 0 0 0 rg BT 520.64 586.05 Td (of ) Tj ET Q q 0 0 0 rg BT 531.65 586.05 Td (NASH ) Tj ET Q q 0 0 0 rg BT 561.57 586.05 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 574.05 Td (TYK-2 ) Tj ET Q q 0 0 0 rg BT 68.11 574.05 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 105.78 574.05 Td (for ) Tj ET Q q 0 0 0 rg BT 120.67 574.05 Td (the ) Tj ET Q q 0 0 0 rg BT 136.12 574.05 Td (treatment ) Tj ET Q q 0 0 0 rg BT 177.11 574.05 Td (of ) Tj ET Q q 0 0 0 rg BT 188.67 574.05 Td (immune ) Tj ET Q q 0 0 0 rg BT 224.67 574.05 Td (diseases ) Tj ET Q q 0 0 0 rg BT 260.67 574.05 Td (such ) Tj ET Q q 0 0 0 rg BT 282.22 574.05 Td (as ) Tj ET Q q 0 0 0 rg BT 293.78 574.05 Td (psoriasis. ) Tj ET Q q 0 0 0 rg BT 334.28 574.05 Td (W) Tj ET Q q 0 0 0 rg BT 342.92 574.05 Td (e ) Tj ET Q q 0 0 0 rg BT 350.58 574.05 Td (also ) Tj ET Q q 0 0 0 rg BT 369.92 574.05 Td (continued ) Tj ET Q q 0 0 0 rg BT 412.58 574.05 Td (to ) Tj ET Q q 0 0 0 rg BT 423.59 574.05 Td (progress ) Tj ET Q q 0 0 0 rg BT 460.70 574.05 Td (our ) Tj ET Q q 0 0 0 rg BT 477.26 574.05 Td (company ) Tj ET Q q 0 0 0 rg BT 517.15 574.05 Td (transformation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 562.05 Td (initiatives ) Tj ET Q q 0 0 0 rg BT 77.94 562.05 Td (enabling ) Tj ET Q q 0 0 0 rg BT 114.87 562.05 Td (us ) Tj ET Q q 0 0 0 rg BT 126.26 562.05 Td (to ) Tj ET Q q 0 0 0 rg BT 136.54 562.05 Td (invest ) Tj ET Q q 0 0 0 rg BT 162.93 562.05 Td (in ) Tj ET Q q 0 0 0 rg BT 173.21 562.05 Td (our ) Tj ET Q q 0 0 0 rg BT 189.04 562.05 Td (highest ) Tj ET Q q 0 0 0 rg BT 220.42 562.05 Td (priority ) Tj ET Q q 0 0 0 rg BT 252.92 562.05 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 290.41 562.05 Td (opportunities.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 538.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.69 538.05 Td (2017, ) Tj ET Q q 0 0 0 rg BT 71.54 538.05 Td (our ) Tj ET Q q 0 0 0 rg BT 87.23 538.05 Td (revenues ) Tj ET Q q 0 0 0 rg BT 125.13 538.05 Td (increased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 165.24 538.05 Td (7%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 178.57 538.05 Td ( ) Tj ET Q q 0 0 0 rg BT 180.93 538.05 Td (as ) Tj ET Q q 0 0 0 rg BT 191.61 538.05 Td (a ) Tj ET Q q 0 0 0 rg BT 198.41 538.05 Td (result ) Tj ET Q q 0 0 0 rg BT 222.98 538.05 Td (of ) Tj ET Q q 0 0 0 rg BT 233.67 538.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 261.58 538.05 Td (demand ) Tj ET Q q 0 0 0 rg BT 295.59 538.05 Td (for ) Tj ET Q q 0 0 0 rg BT 309.61 538.05 Td (our ) Tj ET Q q 0 0 0 rg BT 325.29 538.05 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 369.30 538.05 Td (brands ) Tj ET Q q 0 0 0 rg BT 398.32 538.05 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 438.45 538.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.89 538.05 Td ( ) Tj ET Q q 0 0 0 rg BT 470.25 538.05 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 487.04 538.05 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.38 538.05 Td ( ) Tj ET Q q 0 0 0 rg BT 517.73 538.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 553.41 538.05 Td (of) Tj ET Q q 0 0 0 rg BT 561.56 538.05 Td (fset ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 526.05 Td (by ) Tj ET Q q 0 0 0 rg BT 48.14 526.05 Td (increased ) Tj ET Q q 0 0 0 rg BT 88.02 526.05 Td (competition ) Tj ET Q q 0 0 0 rg BT 137.93 526.05 Td (for ) Tj ET Q q 0 0 0 rg BT 151.72 526.05 Td (established ) Tj ET Q q 0 0 0 rg BT 198.29 526.05 Td (brands, ) Tj ET Q q 0 0 0 rg BT 229.59 526.05 Td (primarily ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 268.94 526.05 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.04 526.05 Td (. ) Tj ET Q q 0 0 0 rg BT 309.52 526.05 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.21 526.05 Td ($2.04) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 349.71 526.05 Td ( ) Tj ET Q q 0 0 0 rg BT 351.84 526.05 Td (decrease ) Tj ET Q q 0 0 0 rg BT 388.39 526.05 Td (in ) Tj ET Q q 0 0 0 rg BT 398.30 526.05 Td (GAAP) Tj ET Q q 0 0 0 rg BT 425.16 526.05 Td ( ) Tj ET Q q 0 0 0 rg BT 427.30 526.05 Td (EPS ) Tj ET Q q 0 0 0 rg BT 446.66 526.05 Td (was ) Tj ET Q q 0 0 0 rg BT 464.35 526.05 Td (due ) Tj ET Q q 0 0 0 rg BT 480.92 526.05 Td (to ) Tj ET Q q 0 0 0 rg BT 490.84 526.05 Td (tax ) Tj ET Q q 0 0 0 rg BT 505.19 526.05 Td (char) Tj ET Q q 0 0 0 rg BT 522.21 526.05 Td (ges ) Tj ET Q q 0 0 0 rg BT 537.68 526.05 Td (attributed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 514.05 Td (to ) Tj ET Q q 0 0 0 rg BT 45.25 514.05 Td (tax ) Tj ET Q q 0 0 0 rg BT 58.94 514.05 Td (reform ) Tj ET Q q 0 0 0 rg BT 87.62 514.05 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 90.95 514.05 Td ($1.76) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 113.45 514.05 Td ( ) Tj ET Q q 0 0 0 rg BT 114.93 514.05 Td (per ) Tj ET Q q 0 0 0 rg BT 129.17 514.05 Td (share\) ) Tj ET Q q 0 0 0 rg BT 155.07 514.05 Td (and ) Tj ET Q q 0 0 0 rg BT 170.98 514.05 Td (to ) Tj ET Q q 0 0 0 rg BT 180.24 514.05 Td (a ) Tj ET Q q 0 0 0 rg BT 186.15 514.05 Td (lesser ) Tj ET Q q 0 0 0 rg BT 210.39 514.05 Td (extent ) Tj ET Q q 0 0 0 rg BT 236.30 514.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 263.32 514.05 Td (license, ) Tj ET Q q 0 0 0 rg BT 295.05 514.05 Td (asset ) Tj ET Q q 0 0 0 rg BT 315.97 514.05 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 361.32 514.05 Td (and ) Tj ET Q q 0 0 0 rg BT 377.23 514.05 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 429.80 514.05 Td (related ) Tj ET Q q 0 0 0 rg BT 458.48 514.05 Td (char) Tj ET Q q 0 0 0 rg BT 475.50 514.05 Td (ges ) Tj ET Q q 0 0 0 rg BT 490.31 514.05 Td (and ) Tj ET Q q 0 0 0 rg BT 506.22 514.05 Td (lower ) Tj ET Q q 0 0 0 rg BT 530.46 514.05 Td (divestiture- ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 502.05 Td (related ) Tj ET Q q 0 0 0 rg BT 64.98 502.05 Td (income. ) Tj ET Q q 0 0 0 rg BT 98.56 502.05 Td (These ) Tj ET Q q 0 0 0 rg BT 124.22 502.05 Td (items ) Tj ET Q q 0 0 0 rg BT 147.66 502.05 Td (were ) Tj ET Q q 0 0 0 rg BT 168.87 502.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 203.97 502.05 Td (of) Tj ET Q q 0 0 0 rg BT 212.12 502.05 Td (fset ) Tj ET Q q 0 0 0 rg BT 228.34 502.05 Td (by ) Tj ET Q q 0 0 0 rg BT 240.12 502.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 267.44 502.05 Td (revenues, ) Tj ET Q q 0 0 0 rg BT 307.26 502.05 Td (royalties ) Tj ET Q q 0 0 0 rg BT 343.47 502.05 Td (and ) Tj ET Q q 0 0 0 rg BT 359.69 502.05 Td (licensing ) Tj ET Q q 0 0 0 rg BT 397.57 502.05 Td (income ) Tj ET Q q 0 0 0 rg BT 428.78 502.05 Td (and ) Tj ET Q q 0 0 0 rg BT 445.00 502.05 Td (a ) Tj ET Q q 0 0 0 rg BT 451.22 502.05 Td (patent-infringement ) Tj ET Q q 0 0 0 rg BT 532.41 502.05 Td (settlement. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 490.05 Td (After ) Tj ET Q q 0 0 0 rg BT 59.93 490.05 Td (adjusting ) Tj ET Q q 0 0 0 rg BT 99.42 490.05 Td (for ) Tj ET Q q 0 0 0 rg BT 113.91 490.05 Td (the ) Tj ET Q q 0 0 0 rg BT 128.96 490.05 Td (impact ) Tj ET Q q 0 0 0 rg BT 159.00 490.05 Td (of ) Tj ET Q q 0 0 0 rg BT 170.16 490.05 Td (tax ) Tj ET Q q 0 0 0 rg BT 185.21 490.05 Td (reform ) Tj ET Q q 0 0 0 rg BT 215.24 490.05 Td (and ) Tj ET Q q 0 0 0 rg BT 232.51 490.05 Td (other ) Tj ET Q q 0 0 0 rg BT 255.89 490.05 Td (specified ) Tj ET Q q 0 0 0 rg BT 294.81 490.05 Td (items, ) Tj ET Q q 0 0 0 rg BT 321.81 490.05 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 366.99 490.05 Td ( ) Tj ET Q q 0 0 0 rg BT 369.82 490.05 Td (EPS ) Tj ET Q q 0 0 0 rg BT 389.88 490.05 Td (increased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.47 490.05 Td ($0.18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.97 490.05 Td ( ) Tj ET Q q 0 0 0 rg BT 455.79 490.05 Td (primarily ) Tj ET Q q 0 0 0 rg BT 495.84 490.05 Td (as ) Tj ET Q q 0 0 0 rg BT 507.00 490.05 Td (a ) Tj ET Q q 0 0 0 rg BT 514.26 490.05 Td (result ) Tj ET Q q 0 0 0 rg BT 539.31 490.05 Td (of ) Tj ET Q q 0 0 0 rg BT 550.47 490.05 Td (higher ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 478.05 Td (revenues ) Tj ET Q q 0 0 0 rg BT 74.04 478.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 109.86 478.05 Td (of) Tj ET Q q 0 0 0 rg BT 118.01 478.05 Td (fset ) Tj ET Q q 0 0 0 rg BT 134.95 478.05 Td (by ) Tj ET Q q 0 0 0 rg BT 147.45 478.05 Td (product ) Tj ET Q q 0 0 0 rg BT 180.49 478.05 Td (mix ) Tj ET Q q 0 0 0 rg BT 198.55 478.05 Td (and ) Tj ET Q q 0 0 0 rg BT 215.49 478.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 243.53 478.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 267.70 478.05 Td (expenses ) Tj ET Q q 0 0 0 rg BT 306.30 478.05 Td (supporting ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 351.58 478.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.02 478.05 Td ( ) Tj ET Q q 0 0 0 rg BT 383.52 478.05 Td (and ) Tj ET Q q 0 0 0 rg BT 400.46 478.05 Td (other ) Tj ET Q q 0 0 0 rg BT 423.50 478.05 Td (IO ) Tj ET Q q 0 0 0 rg BT 436.56 478.05 Td (programs.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 454.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.45 454.05 Td (2016, ) Tj ET Q q 0 0 0 rg BT 71.07 454.05 Td (our ) Tj ET Q q 0 0 0 rg BT 86.52 454.05 Td (revenues ) Tj ET Q q 0 0 0 rg BT 124.17 454.05 Td (increased ) Tj ET Q q 0 0 0 rg BT 164.05 454.05 Td (17% ) Tj ET Q q 0 0 0 rg BT 184.50 454.05 Td (as ) Tj ET Q q 0 0 0 rg BT 194.95 454.05 Td (a ) Tj ET Q q 0 0 0 rg BT 201.50 454.05 Td (result ) Tj ET Q q 0 0 0 rg BT 225.84 454.05 Td (of ) Tj ET Q q 0 0 0 rg BT 236.29 454.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 263.95 454.05 Td (demand ) Tj ET Q q 0 0 0 rg BT 297.73 454.05 Td (for ) Tj ET Q q 0 0 0 rg BT 311.51 454.05 Td (our ) Tj ET Q q 0 0 0 rg BT 326.96 454.05 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 370.73 454.05 Td (brands ) Tj ET Q q 0 0 0 rg BT 399.51 454.05 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 439.40 454.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 468.84 454.05 Td ( ) Tj ET Q q 0 0 0 rg BT 470.96 454.05 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 487.51 454.05 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.85 454.05 Td ( ) Tj ET Q q 0 0 0 rg BT 517.97 454.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 553.41 454.05 Td (of) Tj ET Q q 0 0 0 rg BT 561.56 454.05 Td (fset ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 442.05 Td (by ) Tj ET Q q 0 0 0 rg BT 49.84 442.05 Td (the ) Tj ET Q q 0 0 0 rg BT 65.89 442.05 Td (expiration ) Tj ET Q q 0 0 0 rg BT 110.28 442.05 Td (of ) Tj ET Q q 0 0 0 rg BT 122.44 442.05 Td (our ) Tj ET Q q 0 0 0 rg BT 139.61 442.05 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 161.24 442.05 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 239.48 442.05 Td (rights ) Tj ET Q q 0 0 0 rg BT 266.10 442.05 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 277.72 442.05 Td (Abilify) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.38 442.05 Td (*, ) Tj ET Q q 0 0 0 rg BT 315.72 442.05 Td (the ) Tj ET Q q 0 0 0 rg BT 331.77 442.05 Td (transfer ) Tj ET Q q 0 0 0 rg BT 366.15 442.05 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 378.32 442.05 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.31 442.05 Td (* ) Tj ET Q q 0 0 0 rg BT 417.15 442.05 Td (rights ) Tj ET Q q 0 0 0 rg BT 443.77 442.05 Td (in ) Tj ET Q q 0 0 0 rg BT 455.39 442.05 Td (North ) Tj ET Q q 0 0 0 rg BT 481.71 442.05 Td (America ) Tj ET Q q 0 0 0 rg BT 519.97 442.05 Td (and ) Tj ET Q q 0 0 0 rg BT 538.25 442.05 Td (increased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 430.05 Td (competition ) Tj ET Q q 0 0 0 rg BT 87.38 430.05 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 102.64 430.05 Td (Reyataz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 134.30 430.05 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 140.41 430.05 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 169.29 430.05 Td ( ) Tj ET Q q 0 0 0 rg BT 172.90 430.05 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 190.95 430.05 Td (Baraclude) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 232.60 430.05 Td ( ) Tj ET Q q 0 0 0 rg BT 236.21 430.05 Td (in ) Tj ET Q q 0 0 0 rg BT 247.59 430.05 Td (certain ) Tj ET Q q 0 0 0 rg BT 278.40 430.05 Td (markets. ) Tj ET Q q 0 0 0 rg BT 315.91 430.05 Td (The ) Tj ET Q q 0 0 0 rg BT 335.06 430.05 Td ($1.72 ) Tj ET Q q 0 0 0 rg BT 361.17 430.05 Td (increase ) Tj ET Q q 0 0 0 rg BT 397.53 430.05 Td (in ) Tj ET Q q 0 0 0 rg BT 408.92 430.05 Td (GAAP) Tj ET Q q 0 0 0 rg BT 435.77 430.05 Td ( ) Tj ET Q q 0 0 0 rg BT 439.38 430.05 Td (EPS ) Tj ET Q q 0 0 0 rg BT 460.22 430.05 Td (was ) Tj ET Q q 0 0 0 rg BT 479.38 430.05 Td (due ) Tj ET Q q 0 0 0 rg BT 497.42 430.05 Td (to ) Tj ET Q q 0 0 0 rg BT 508.81 430.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 537.96 430.05 Td (revenues, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 418.05 Td (divestiture-related ) Tj ET Q q 0 0 0 rg BT 112.35 418.05 Td (income ) Tj ET Q q 0 0 0 rg BT 145.40 418.05 Td (and ) Tj ET Q q 0 0 0 rg BT 163.45 418.05 Td (lower ) Tj ET Q q 0 0 0 rg BT 189.82 418.05 Td (license ) Tj ET Q q 0 0 0 rg BT 221.20 418.05 Td (and ) Tj ET Q q 0 0 0 rg BT 239.25 418.05 Td (asset ) Tj ET Q q 0 0 0 rg BT 262.29 418.05 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 309.79 418.05 Td (char) Tj ET Q q 0 0 0 rg BT 326.81 418.05 Td (ges ) Tj ET Q q 0 0 0 rg BT 343.75 418.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 380.68 418.05 Td (of) Tj ET Q q 0 0 0 rg BT 388.83 418.05 Td (fset ) Tj ET Q q 0 0 0 rg BT 406.88 418.05 Td (by ) Tj ET Q q 0 0 0 rg BT 420.49 418.05 Td (higher ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 449.65 418.05 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.09 418.05 Td ( ) Tj ET Q q 0 0 0 rg BT 482.70 418.05 Td (related ) Tj ET Q q 0 0 0 rg BT 513.51 418.05 Td (expenses. ) Tj ET Q q 0 0 0 rg BT 554.92 418.05 Td (After ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 406.05 Td (adjusting ) Tj ET Q q 0 0 0 rg BT 76.16 406.05 Td (for ) Tj ET Q q 0 0 0 rg BT 91.31 406.05 Td (the ) Tj ET Q q 0 0 0 rg BT 107.02 406.05 Td (impact ) Tj ET Q q 0 0 0 rg BT 137.73 406.05 Td (of ) Tj ET Q q 0 0 0 rg BT 149.55 406.05 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 195.26 406.05 Td (gains, ) Tj ET Q q 0 0 0 rg BT 222.36 406.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 247.52 406.05 Td (license ) Tj ET Q q 0 0 0 rg BT 278.78 406.05 Td (and ) Tj ET Q q 0 0 0 rg BT 296.71 406.05 Td (asset ) Tj ET Q q 0 0 0 rg BT 319.65 406.05 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 367.02 406.05 Td (char) Tj ET Q q 0 0 0 rg BT 384.05 406.05 Td (ges ) Tj ET Q q 0 0 0 rg BT 400.87 406.05 Td (and ) Tj ET Q q 0 0 0 rg BT 418.80 406.05 Td (other ) Tj ET Q q 0 0 0 rg BT 442.84 406.05 Td (specified ) Tj ET Q q 0 0 0 rg BT 482.43 406.05 Td (items, ) Tj ET Q q 0 0 0 rg BT 510.09 406.05 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 555.27 406.05 Td ( ) Tj ET Q q 0 0 0 rg BT 558.77 406.05 Td (EPS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 394.05 Td (increased ) Tj ET Q q 0 0 0 rg BT 76.25 394.05 Td (by ) Tj ET Q q 0 0 0 rg BT 88.75 394.05 Td ($0.82 ) Tj ET Q q 0 0 0 rg BT 113.75 394.05 Td (primarily ) Tj ET Q q 0 0 0 rg BT 153.47 394.05 Td (as ) Tj ET Q q 0 0 0 rg BT 164.30 394.05 Td (a ) Tj ET Q q 0 0 0 rg BT 171.23 394.05 Td (result ) Tj ET Q q 0 0 0 rg BT 195.95 394.05 Td (of ) Tj ET Q q 0 0 0 rg BT 206.78 394.05 Td (higher ) Tj ET Q q 0 0 0 rg BT 234.83 394.05 Td (revenues ) Tj ET Q q 0 0 0 rg BT 272.87 394.05 Td (partially ) Tj ET Q q 0 0 0 rg BT 308.69 394.05 Td (of) Tj ET Q q 0 0 0 rg BT 316.83 394.05 Td (fset ) Tj ET Q q 0 0 0 rg BT 333.77 394.05 Td (by ) Tj ET Q q 0 0 0 rg BT 346.27 394.05 Td (product ) Tj ET Q q 0 0 0 rg BT 379.32 394.05 Td (mix.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 334.05 Td (Highlights) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.05 Td (The following table summarizes our financial information:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 282.55 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 282.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 282.55 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 282.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 282.55 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 282.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 282.55 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 256.55 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 256.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 256.55 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 256.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 256.55 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 256.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 256.55 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 230.55 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 230.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 230.55 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 230.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 230.55 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 230.55 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 230.55 71.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 294.54999999999995 m 426.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 426.5 294.54999999999995 m 430.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 294.54999999999995 m 501.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 294.54999999999995 m 505.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 294.54999999999995 m 576.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 282.54999999999995 m 426.5 282.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 294.54999999999995 m 501.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 282.54999999999995 m 501.5 282.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 294.54999999999995 m 505.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 294.54999999999995 m 576.5 294.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 282.54999999999995 m 576.5 282.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 282.54999999999995 m 426.5 282.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 282.54999999999995 m 501.5 282.54999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 282.54999999999995 m 576.5 282.54999999999995 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 298.50 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 298.63 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 298.63 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 298.63 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 298.63 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 286.50 Td (Dollars in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 383.00 286.63 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 457.50 286.63 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 286.63 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 273.12 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 273.12 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.00 273.12 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 395.15 273.12 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 273.12 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 273.12 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 273.12 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 273.12 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 247.12 Td (Diluted Earnings Per Share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 234.12 Td (GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.15 234.12 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 234.12 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 234.12 Td (0.93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 221.12 Td (Non-GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.15 221.12 Td (3.01) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 221.12 Td (2.83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 221.12 Td (2.01) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 196.45 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.86 196.45 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 99.05 196.45 Td ( ) Tj ET Q q 0 0 0 rg BT 101.36 196.45 Td (financial ) Tj ET Q q 0 0 0 rg BT 138.65 196.45 Td (measures, ) Tj ET Q q 0 0 0 rg BT 180.67 196.45 Td (including ) Tj ET Q q 0 0 0 rg BT 220.76 196.45 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 265.94 196.45 Td ( ) Tj ET Q q 0 0 0 rg BT 268.26 196.45 Td (earnings ) Tj ET Q q 0 0 0 rg BT 304.44 196.45 Td (and ) Tj ET Q q 0 0 0 rg BT 321.20 196.45 Td (related ) Tj ET Q q 0 0 0 rg BT 350.71 196.45 Td (EPS ) Tj ET Q q 0 0 0 rg BT 370.25 196.45 Td (information, ) Tj ET Q q 0 0 0 rg BT 422.28 196.45 Td (are ) Tj ET Q q 0 0 0 rg BT 436.80 196.45 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 472.43 196.45 Td (to ) Tj ET Q q 0 0 0 rg BT 482.52 196.45 Td (exclude ) Tj ET Q q 0 0 0 rg BT 515.93 196.45 Td (specified ) Tj ET Q q 0 0 0 rg BT 554.33 196.45 Td (items ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 184.45 Td (that ) Tj ET Q q 0 0 0 rg BT 53.86 184.45 Td (represent ) Tj ET Q q 0 0 0 rg BT 93.36 184.45 Td (certain ) Tj ET Q q 0 0 0 rg BT 123.42 184.45 Td (costs, ) Tj ET Q q 0 0 0 rg BT 148.78 184.45 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 190.24 184.45 Td (gains ) Tj ET Q q 0 0 0 rg BT 214.21 184.45 Td (and ) Tj ET Q q 0 0 0 rg BT 231.51 184.45 Td (losses ) Tj ET Q q 0 0 0 rg BT 258.26 184.45 Td (and ) Tj ET Q q 0 0 0 rg BT 275.56 184.45 Td (other ) Tj ET Q q 0 0 0 rg BT 298.97 184.45 Td (items ) Tj ET Q q 0 0 0 rg BT 323.49 184.45 Td (impacting ) Tj ET Q q 0 0 0 rg BT 366.34 184.45 Td (the ) Tj ET Q q 0 0 0 rg BT 381.42 184.45 Td (comparability ) Tj ET Q q 0 0 0 rg BT 439.82 184.45 Td (of ) Tj ET Q q 0 0 0 rg BT 451.01 184.45 Td (financial ) Tj ET Q q 0 0 0 rg BT 488.85 184.45 Td (results. ) Tj ET Q q 0 0 0 rg BT 520.32 184.45 Td (For ) Tj ET Q q 0 0 0 rg BT 537.07 184.45 Td (a ) Tj ET Q q 0 0 0 rg BT 544.37 184.45 Td (detailed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 172.45 Td (listing ) Tj ET Q q 0 0 0 rg BT 62.50 172.45 Td (of ) Tj ET Q q 0 0 0 rg BT 72.32 172.45 Td (all ) Tj ET Q q 0 0 0 rg BT 83.80 172.45 Td (specified ) Tj ET Q q 0 0 0 rg BT 121.39 172.45 Td (items ) Tj ET Q q 0 0 0 rg BT 144.54 172.45 Td (and ) Tj ET Q q 0 0 0 rg BT 160.47 172.45 Td (further ) Tj ET Q q 0 0 0 rg BT 189.17 172.45 Td (information ) Tj ET Q q 0 0 0 rg BT 237.87 172.45 Td (and ) Tj ET Q q 0 0 0 rg BT 253.80 172.45 Td (reconciliations ) Tj ET Q q 0 0 0 rg BT 314.16 172.45 Td (of ) Tj ET Q q 0 0 0 rg BT 323.98 172.45 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 369.17 172.45 Td ( ) Tj ET Q q 0 0 0 rg BT 370.66 172.45 Td (financial ) Tj ET Q q 0 0 0 rg BT 407.13 172.45 Td (measures ) Tj ET Q q 0 0 0 rg BT 445.83 172.45 Td (refer ) Tj ET Q q 0 0 0 rg BT 466.18 172.45 Td (to ) Tj ET Q q 0 0 0 rg BT 475.45 172.45 Td (“—Non-GAAP) Tj ET Q q 0 0 0 rg BT 537.30 172.45 Td ( ) Tj ET Q q 0 0 0 rg BT 538.79 172.45 Td (Financial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 160.45 Td (Measures.") Tj ET Q endstream endobj 61 0 obj <> endobj 62 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (30) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Significant Pr) Tj ET Q q 0 0 0 rg BT 94.98 749.25 Td (oduct and Pipeline ) Tj ET Q q 0 0 0 rg BT 176.39 749.25 Td (Appr) Tj ET Q q 0 0 0 rg BT 198.99 749.25 Td (ovals) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 727.65 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 727.65 Td (following ) Tj ET Q q 0 0 0 rg BT 95.43 727.65 Td (is ) Tj ET Q q 0 0 0 rg BT 104.60 727.65 Td (a ) Tj ET Q q 0 0 0 rg BT 111.54 727.65 Td (summary ) Tj ET Q q 0 0 0 rg BT 151.26 727.65 Td (of ) Tj ET Q q 0 0 0 rg BT 162.09 727.65 Td (the ) Tj ET Q q 0 0 0 rg BT 176.81 727.65 Td (15 ) Tj ET Q q 0 0 0 rg BT 189.31 727.65 Td (significant ) Tj ET Q q 0 0 0 rg BT 234.02 727.65 Td (approvals ) Tj ET Q q 0 0 0 rg BT 275.39 727.65 Td (received ) Tj ET Q q 0 0 0 rg BT 311.76 727.65 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.04 727.65 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.04 727.65 Td (.) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 717.15 m 35.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 717.15 m 134.5 717.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 717.15 m 134.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 717.15 m 210.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 717.15 m 210.5 717.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 717.15 m 210.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 717.15 m 575.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 717.15 m 575.5 717.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 702.15 m 35.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 702.15 m 134.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 702.15 m 134.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 702.15 m 210.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 702.15 m 210.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 702.15 m 210.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 702.15 m 575.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 702.15 m 575.5 702.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 667.15 m 575.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 667.15 m 35.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 667.15 m 134.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 667.15 m 210.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 667.15 m 210.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 667.15 m 210.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 667.15 m 575.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 667.15 m 575.5 667.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 642.15 m 575.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 642.15 m 35.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 642.15 m 134.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 642.15 m 210.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 642.15 m 210.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 642.15 m 575.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 642.15 m 575.5 642.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 617.15 m 575.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 617.15 m 35.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 617.15 m 134.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 617.15 m 210.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 617.15 m 210.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 617.15 m 210.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 617.15 m 575.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 617.15 m 575.5 617.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 592.15 m 575.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 592.15 m 35.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 592.15 m 134.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 592.15 m 210.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 592.15 m 210.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 592.15 m 210.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 592.15 m 575.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 592.15 m 575.5 592.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 557.15 m 575.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 557.15 m 35.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 557.15 m 134.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 557.15 m 210.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 557.15 m 210.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 557.15 m 210.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 557.15 m 575.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 557.15 m 575.5 557.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 532.15 m 575.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 532.15 m 35.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 532.15 m 134.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 532.15 m 210.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 532.15 m 210.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 532.15 m 210.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 532.15 m 575.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 532.15 m 575.5 532.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 507.15 m 35.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 507.15 m 134.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 482.15 m 134.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 507.15 m 210.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 507.15 m 210.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 507.15 m 210.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 507.15 m 575.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 507.15 m 575.5 507.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 482.15 m 35.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 482.15 m 134.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 482.15 m 134.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 482.15 m 210.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 482.15 m 210.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 482.15 m 210.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 482.15 m 575.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 482.15 m 575.5 482.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 447.15 m 35.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 447.15 m 134.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 447.15 m 210.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 447.15 m 210.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 447.15 m 575.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 447.15 m 575.5 447.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 432.15 m 575.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 432.15 m 35.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 432.15 m 134.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 432.15 m 210.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 432.15 m 210.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 432.15 m 210.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 432.15 m 575.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 432.15 m 575.5 432.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 407.15 m 35.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 407.15 m 134.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 407.15 m 134.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 382.15 m 134.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 407.15 m 210.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 407.15 m 210.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 382.15 m 210.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 407.15 m 210.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 407.15 m 575.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 407.15 m 575.5 407.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 382.15 m 575.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 382.15 m 35.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 382.15 m 134.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 382.15 m 134.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 357.15 m 134.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 382.15 m 210.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 382.15 m 210.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 357.15 m 210.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 382.15 m 210.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 382.15 m 575.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 382.15 m 575.5 382.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 357.15 m 575.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 357.15 m 35.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 312.15 m 134.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 357.15 m 134.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 357.15 m 210.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 357.15 m 210.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 134.5 312.15 m 210.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 357.15 m 210.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 357.15 m 575.5 312.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 357.15 m 575.5 357.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 210.5 312.15 m 575.5 312.15 l s BT /F2 10.00 Tf ET q 0 0 0 rg BT 67.35 706.83 Td (Pr) Tj ET Q q 0 0 0 rg BT 77.81 706.83 Td (oduct) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 162.00 706.83 Td (Date) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 372.30 706.83 Td (Appr) Tj ET Q q 0 0 0 rg BT 394.90 706.83 Td (oval) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 69.75 589.88 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 140.20 682.27 Td (December 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 692.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 692.27 Td ( ) Tj ET Q q 0 0 0 rg BT 235.25 692.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 273.03 692.27 Td (of ) Tj ET Q q 0 0 0 rg BT 284.15 692.27 Td (injection ) Tj ET Q q 0 0 0 rg BT 321.94 692.27 Td (for ) Tj ET Q q 0 0 0 rg BT 336.39 692.27 Td (intravenous ) Tj ET Q q 0 0 0 rg BT 385.84 692.27 Td (use ) Tj ET Q q 0 0 0 rg BT 401.97 692.27 Td (for ) Tj ET Q q 0 0 0 rg BT 416.42 692.27 Td (the ) Tj ET Q q 0 0 0 rg BT 431.43 692.27 Td (adjuvant ) Tj ET Q q 0 0 0 rg BT 468.66 692.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 509.21 692.27 Td (of ) Tj ET Q q 0 0 0 rg BT 520.34 692.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 554.23 692.27 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 682.27 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 257.97 682.27 Td (with ) Tj ET Q q 0 0 0 rg BT 279.06 682.27 Td (involvement ) Tj ET Q q 0 0 0 rg BT 332.37 682.27 Td (of ) Tj ET Q q 0 0 0 rg BT 344.02 682.27 Td (lymph ) Tj ET Q q 0 0 0 rg BT 372.90 682.27 Td (nodes ) Tj ET Q q 0 0 0 rg BT 399.54 682.27 Td (or ) Tj ET Q q 0 0 0 rg BT 411.19 682.27 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 455.05 682.27 Td (disease ) Tj ET Q q 0 0 0 rg BT 487.24 682.27 Td (who ) Tj ET Q q 0 0 0 rg BT 507.78 682.27 Td (have ) Tj ET Q q 0 0 0 rg BT 529.98 682.27 Td (under) Tj ET Q q 0 0 0 rg BT 552.65 682.27 Td (gone ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 672.27 Td (complete ) Tj ET Q q 0 0 0 rg BT 252.15 672.27 Td (resection.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.35 639.77 Td (September 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 657.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 657.27 Td ( ) Tj ET Q q 0 0 0 rg BT 234.40 657.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 271.34 657.27 Td (for ) Tj ET Q q 0 0 0 rg BT 284.95 657.27 Td (the ) Tj ET Q q 0 0 0 rg BT 299.11 657.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 338.82 657.27 Td (of ) Tj ET Q q 0 0 0 rg BT 349.10 657.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 382.16 657.27 Td (with ) Tj ET Q q 0 0 0 rg BT 401.88 657.27 Td (HCC, ) Tj ET Q q 0 0 0 rg BT 426.90 657.27 Td (a ) Tj ET Q q 0 0 0 rg BT 433.28 657.27 Td (type ) Tj ET Q q 0 0 0 rg BT 452.45 657.27 Td (of ) Tj ET Q q 0 0 0 rg BT 462.73 657.27 Td (liver ) Tj ET Q q 0 0 0 rg BT 483.00 657.27 Td (cancer) Tj ET Q q 0 0 0 rg BT 508.89 657.27 Td (, ) Tj ET Q q 0 0 0 rg BT 513.14 657.27 Td (who ) Tj ET Q q 0 0 0 rg BT 532.31 657.27 Td (have ) Tj ET Q q 0 0 0 rg BT 553.14 657.27 Td (been ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 647.27 Td (previously ) Tj ET Q q 0 0 0 rg BT 257.72 647.27 Td (treated ) Tj ET Q q 0 0 0 rg BT 287.42 647.27 Td (with ) Tj ET Q q 0 0 0 rg BT 307.70 647.27 Td (sorafenib.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 632.27 Td (Approval ) Tj ET Q q 0 0 0 rg BT 253.76 632.27 Td (in ) Tj ET Q q 0 0 0 rg BT 264.52 632.27 Td (Japan ) Tj ET Q q 0 0 0 rg BT 290.28 632.27 Td (for ) Tj ET Q q 0 0 0 rg BT 304.92 632.27 Td (the ) Tj ET Q q 0 0 0 rg BT 320.13 632.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 360.88 632.27 Td (of ) Tj ET Q q 0 0 0 rg BT 372.19 632.27 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 425.15 632.27 Td (advanced ) Tj ET Q q 0 0 0 rg BT 465.89 632.27 Td (or ) Tj ET Q q 0 0 0 rg BT 477.21 632.27 Td (recurrent ) Tj ET Q q 0 0 0 rg BT 516.28 632.27 Td (gastric ) Tj ET Q q 0 0 0 rg BT 545.92 632.27 Td (cancer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 622.27 Td (which ) Tj ET Q q 0 0 0 rg BT 239.94 622.27 Td (has ) Tj ET Q q 0 0 0 rg BT 255.77 622.27 Td (progressed ) Tj ET Q q 0 0 0 rg BT 301.59 622.27 Td (after ) Tj ET Q q 0 0 0 rg BT 322.40 622.27 Td (chemotherapy) Tj ET Q q 0 0 0 rg BT 378.72 622.27 Td (, ) Tj ET Q q 0 0 0 rg BT 383.40 622.27 Td (received ) Tj ET Q q 0 0 0 rg BT 419.76 622.27 Td (by ) Tj ET Q q 0 0 0 rg BT 432.26 622.27 Td (our ) Tj ET Q q 0 0 0 rg BT 448.09 622.27 Td (alliance ) Tj ET Q q 0 0 0 rg BT 481.68 622.27 Td (partner) Tj ET Q q 0 0 0 rg BT 509.79 622.27 Td (, ) Tj ET Q q 0 0 0 rg BT 514.59 622.27 Td (Ono.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 146.30 602.27 Td (August 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 607.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 607.27 Td ( ) Tj ET Q q 0 0 0 rg BT 234.05 607.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 270.64 607.27 Td (for ) Tj ET Q q 0 0 0 rg BT 283.90 607.27 Td (the ) Tj ET Q q 0 0 0 rg BT 297.72 607.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 337.08 607.27 Td (of ) Tj ET Q q 0 0 0 rg BT 347.01 607.27 Td (adult ) Tj ET Q q 0 0 0 rg BT 368.60 607.27 Td (and ) Tj ET Q q 0 0 0 rg BT 384.64 607.27 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 421.22 607.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 453.93 607.27 Td (with ) Tj ET Q q 0 0 0 rg BT 473.31 607.27 Td (MSI-H ) Tj ET Q q 0 0 0 rg BT 503.24 607.27 Td (or ) Tj ET Q q 0 0 0 rg BT 513.17 607.27 Td (dMMR ) Tj ET Q q 0 0 0 rg BT 544.23 607.27 Td (mCRC ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 597.27 Td (that ) Tj ET Q q 0 0 0 rg BT 229.79 597.27 Td (has ) Tj ET Q q 0 0 0 rg BT 244.92 597.27 Td (progressed ) Tj ET Q q 0 0 0 rg BT 290.04 597.27 Td (following ) Tj ET Q q 0 0 0 rg BT 330.73 597.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 370.29 597.27 Td (with ) Tj ET Q q 0 0 0 rg BT 389.87 597.27 Td (a ) Tj ET Q q 0 0 0 rg BT 396.10 597.27 Td (fluoropyrimidine, ) Tj ET Q q 0 0 0 rg BT 468.72 597.27 Td (oxaliplatin ) Tj ET Q q 0 0 0 rg BT 513.29 597.27 Td (and ) Tj ET Q q 0 0 0 rg BT 529.53 597.27 Td (irinotecan.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 151.55 572.27 Td (June 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 582.27 Td (EC ) Tj ET Q q 0 0 0 rg BT 231.05 582.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 271.31 582.27 Td (for ) Tj ET Q q 0 0 0 rg BT 288.24 582.27 Td (the ) Tj ET Q q 0 0 0 rg BT 305.73 582.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 348.76 582.27 Td (of ) Tj ET Q q 0 0 0 rg BT 362.37 582.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 398.74 582.27 Td (with ) Tj ET Q q 0 0 0 rg BT 421.79 582.27 Td (previously ) Tj ET Q q 0 0 0 rg BT 469.28 582.27 Td (treated ) Tj ET Q q 0 0 0 rg BT 501.76 582.27 Td (locally ) Tj ET Q q 0 0 0 rg BT 534.24 582.27 Td (advanced ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 572.27 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 266.27 572.27 Td (or ) Tj ET Q q 0 0 0 rg BT 277.90 572.27 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 321.73 572.27 Td (urothelial ) Tj ET Q q 0 0 0 rg BT 363.35 572.27 Td (carcinoma, ) Tj ET Q q 0 0 0 rg BT 410.79 572.27 Td (a ) Tj ET Q q 0 0 0 rg BT 418.52 572.27 Td (type ) Tj ET Q q 0 0 0 rg BT 439.04 572.27 Td (of ) Tj ET Q q 0 0 0 rg BT 450.66 572.27 Td (bladder ) Tj ET Q q 0 0 0 rg BT 483.95 572.27 Td (cancer) Tj ET Q q 0 0 0 rg BT 509.83 572.27 Td (, ) Tj ET Q q 0 0 0 rg BT 515.43 572.27 Td (in ) Tj ET Q q 0 0 0 rg BT 526.50 572.27 Td (adults ) Tj ET Q q 0 0 0 rg BT 553.69 572.27 Td (after ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 562.27 Td (failure ) Tj ET Q q 0 0 0 rg BT 241.59 562.27 Td (of ) Tj ET Q q 0 0 0 rg BT 252.42 562.27 Td (platinum-containing ) Tj ET Q q 0 0 0 rg BT 336.02 562.27 Td (therapy) Tj ET Q q 0 0 0 rg BT 365.68 562.27 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 150.15 542.27 Td (April 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 547.27 Td (EC ) Tj ET Q q 0 0 0 rg BT 228.19 547.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 265.58 547.27 Td (for ) Tj ET Q q 0 0 0 rg BT 279.65 547.27 Td (the ) Tj ET Q q 0 0 0 rg BT 294.28 547.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 334.44 547.27 Td (of ) Tj ET Q q 0 0 0 rg BT 345.18 547.27 Td (SCCHN ) Tj ET Q q 0 0 0 rg BT 380.94 547.27 Td (in ) Tj ET Q q 0 0 0 rg BT 391.12 547.27 Td (adults ) Tj ET Q q 0 0 0 rg BT 417.42 547.27 Td (progressing ) Tj ET Q q 0 0 0 rg BT 466.49 547.27 Td (on ) Tj ET Q q 0 0 0 rg BT 478.90 547.27 Td (or ) Tj ET Q q 0 0 0 rg BT 489.63 547.27 Td (after ) Tj ET Q q 0 0 0 rg BT 510.36 547.27 Td (platinum-based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 537.27 Td (therapy) Tj ET Q q 0 0 0 rg BT 242.66 537.27 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 147.70 517.27 Td (March 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 522.27 Td (Approval ) Tj ET Q q 0 0 0 rg BT 252.47 522.27 Td (in ) Tj ET Q q 0 0 0 rg BT 261.96 522.27 Td (Japan ) Tj ET Q q 0 0 0 rg BT 286.43 522.27 Td (for ) Tj ET Q q 0 0 0 rg BT 299.80 522.27 Td (the ) Tj ET Q q 0 0 0 rg BT 313.72 522.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 353.18 522.27 Td (of ) Tj ET Q q 0 0 0 rg BT 363.22 522.27 Td (recurrent ) Tj ET Q q 0 0 0 rg BT 401.01 522.27 Td (or ) Tj ET Q q 0 0 0 rg BT 411.05 522.27 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 453.29 522.27 Td (HNC, ) Tj ET Q q 0 0 0 rg BT 478.61 522.27 Td (received ) Tj ET Q q 0 0 0 rg BT 514.17 522.27 Td (by ) Tj ET Q q 0 0 0 rg BT 525.88 522.27 Td (our ) Tj ET Q q 0 0 0 rg BT 540.92 522.27 Td (alliance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 512.27 Td (partner) Tj ET Q q 0 0 0 rg BT 241.12 512.27 Td (, ) Tj ET Q q 0 0 0 rg BT 245.92 512.27 Td (Ono.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 142.70 492.27 Td (February 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 497.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 497.27 Td ( ) Tj ET Q q 0 0 0 rg BT 236.04 497.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 274.61 497.27 Td (for ) Tj ET Q q 0 0 0 rg BT 289.85 497.27 Td (the ) Tj ET Q q 0 0 0 rg BT 305.65 497.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 346.99 497.27 Td (of ) Tj ET Q q 0 0 0 rg BT 358.91 497.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 393.60 497.27 Td (with ) Tj ET Q q 0 0 0 rg BT 414.96 497.27 Td (previously ) Tj ET Q q 0 0 0 rg BT 460.76 497.27 Td (treated ) Tj ET Q q 0 0 0 rg BT 491.54 497.27 Td (locally ) Tj ET Q q 0 0 0 rg BT 522.34 497.27 Td (advanced ) Tj ET Q q 0 0 0 rg BT 563.68 497.27 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 487.27 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 256.04 487.27 Td (urothelial ) Tj ET Q q 0 0 0 rg BT 296.86 487.27 Td (carcinoma.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 67.80 442.38 Td (Orencia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 152.40 454.77 Td (July 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 472.27 Td (EC ) Tj ET Q q 0 0 0 rg BT 228.68 472.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 266.57 472.27 Td (for ) Tj ET Q q 0 0 0 rg BT 281.13 472.27 Td (the ) Tj ET Q q 0 0 0 rg BT 296.25 472.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 336.91 472.27 Td (of ) Tj ET Q q 0 0 0 rg BT 348.14 472.27 Td (active ) Tj ET Q q 0 0 0 rg BT 374.91 472.27 Td (PsA) Tj ET Q q 0 0 0 rg BT 391.31 472.27 Td ( ) Tj ET Q q 0 0 0 rg BT 393.94 472.27 Td (in ) Tj ET Q q 0 0 0 rg BT 404.62 472.27 Td (adults ) Tj ET Q q 0 0 0 rg BT 431.41 472.27 Td (for ) Tj ET Q q 0 0 0 rg BT 445.97 472.27 Td (whom ) Tj ET Q q 0 0 0 rg BT 473.87 472.27 Td (the ) Tj ET Q q 0 0 0 rg BT 488.99 472.27 Td (response ) Tj ET Q q 0 0 0 rg BT 526.88 472.27 Td (to ) Tj ET Q q 0 0 0 rg BT 537.56 472.27 Td (previous ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 462.27 Td (disease-modifying ) Tj ET Q q 0 0 0 rg BT 294.77 462.27 Td (antirheumatic ) Tj ET Q q 0 0 0 rg BT 357.65 462.27 Td (drug ) Tj ET Q q 0 0 0 rg BT 383.88 462.27 Td (therapy) Tj ET Q q 0 0 0 rg BT 413.54 462.27 Td (, ) Tj ET Q q 0 0 0 rg BT 423.62 462.27 Td (including ) Tj ET Q q 0 0 0 rg BT 469.29 462.27 Td (methotrexate, ) Tj ET Q q 0 0 0 rg BT 531.89 462.27 Td (has ) Tj ET Q q 0 0 0 rg BT 553.12 462.27 Td (been ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 452.27 Td (inadequate, ) Tj ET Q q 0 0 0 rg BT 261.31 452.27 Td (and ) Tj ET Q q 0 0 0 rg BT 278.25 452.27 Td (additional ) Tj ET Q q 0 0 0 rg BT 320.74 452.27 Td (systemic ) Tj ET Q q 0 0 0 rg BT 358.23 452.27 Td (therapy ) Tj ET Q q 0 0 0 rg BT 390.72 452.27 Td (for ) Tj ET Q q 0 0 0 rg BT 404.88 452.27 Td (psoriatic ) Tj ET Q q 0 0 0 rg BT 441.81 452.27 Td (skin ) Tj ET Q q 0 0 0 rg BT 460.98 452.27 Td (lesions ) Tj ET Q q 0 0 0 rg BT 491.26 452.27 Td (is ) Tj ET Q q 0 0 0 rg BT 500.43 452.27 Td (not ) Tj ET Q q 0 0 0 rg BT 515.71 452.27 Td (required.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 437.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 437.27 Td ( ) Tj ET Q q 0 0 0 rg BT 234.95 437.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 272.44 437.27 Td (for ) Tj ET Q q 0 0 0 rg BT 286.60 437.27 Td (the ) Tj ET Q q 0 0 0 rg BT 301.32 437.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 341.57 437.27 Td (of ) Tj ET Q q 0 0 0 rg BT 352.40 437.27 Td (active ) Tj ET Q q 0 0 0 rg BT 378.78 437.27 Td (PsA) Tj ET Q q 0 0 0 rg BT 395.18 437.27 Td ( ) Tj ET Q q 0 0 0 rg BT 397.40 437.27 Td (in ) Tj ET Q q 0 0 0 rg BT 407.68 437.27 Td (adults.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 147.70 417.27 Td (March 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 422.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.73 422.27 Td ( ) Tj ET Q q 0 0 0 rg BT 234.57 422.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 271.67 422.27 Td (of ) Tj ET Q q 0 0 0 rg BT 282.12 422.27 Td (a ) Tj ET Q q 0 0 0 rg BT 288.67 422.27 Td (new ) Tj ET Q q 0 0 0 rg BT 307.45 422.27 Td (subcutaneous ) Tj ET Q q 0 0 0 rg BT 363.44 422.27 Td (administration ) Tj ET Q q 0 0 0 rg BT 423.33 422.27 Td (option ) Tj ET Q q 0 0 0 rg BT 451.00 422.27 Td (for ) Tj ET Q q 0 0 0 rg BT 464.78 422.27 Td (use ) Tj ET Q q 0 0 0 rg BT 480.23 422.27 Td (in ) Tj ET Q q 0 0 0 rg BT 490.12 422.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 523.34 422.27 Td (two ) Tj ET Q q 0 0 0 rg BT 540.46 422.27 Td (years ) Tj ET Q q 0 0 0 rg BT 563.67 422.27 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 412.27 Td (age ) Tj ET Q q 0 0 0 rg BT 229.38 412.27 Td (and ) Tj ET Q q 0 0 0 rg BT 246.32 412.27 Td (older ) Tj ET Q q 0 0 0 rg BT 269.36 412.27 Td (with ) Tj ET Q q 0 0 0 rg BT 289.64 412.27 Td (moderately ) Tj ET Q q 0 0 0 rg BT 337.12 412.27 Td (to ) Tj ET Q q 0 0 0 rg BT 347.40 412.27 Td (severely ) Tj ET Q q 0 0 0 rg BT 383.21 412.27 Td (active ) Tj ET Q q 0 0 0 rg BT 409.59 412.27 Td (polyarticular ) Tj ET Q q 0 0 0 rg BT 463.18 412.27 Td (JIA.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 69.20 392.38 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.60 392.27 Td (November 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 397.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.45 397.27 Td ( ) Tj ET Q q 0 0 0 rg BT 235.16 397.27 Td (expanded ) Tj ET Q q 0 0 0 rg BT 276.19 397.27 Td (the ) Tj ET Q q 0 0 0 rg BT 291.11 397.27 Td (indication ) Tj ET Q q 0 0 0 rg BT 333.81 397.27 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 348.18 397.27 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.17 397.27 Td ( ) Tj ET Q q 0 0 0 rg BT 380.88 397.27 Td (tablets ) Tj ET Q q 0 0 0 rg BT 409.69 397.27 Td (to ) Tj ET Q q 0 0 0 rg BT 420.17 397.27 Td (include ) Tj ET Q q 0 0 0 rg BT 452.32 397.27 Td (the ) Tj ET Q q 0 0 0 rg BT 467.24 397.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 507.71 397.27 Td (of ) Tj ET Q q 0 0 0 rg BT 518.75 397.27 Td (children ) Tj ET Q q 0 0 0 rg BT 554.22 397.27 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 387.27 Td (Philadelphia ) Tj ET Q q 0 0 0 rg BT 265.49 387.27 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 354.64 387.27 Td (CML) Tj ET Q q 0 0 0 rg BT 375.94 387.27 Td ( ) Tj ET Q q 0 0 0 rg BT 378.44 387.27 Td (in ) Tj ET Q q 0 0 0 rg BT 388.72 387.27 Td (chronic ) Tj ET Q q 0 0 0 rg BT 421.20 387.27 Td (phase.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 70.85 367.38 Td (Y) Tj ET Q q 0 0 0 rg BT 75.85 367.38 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 152.40 367.27 Td (July 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 372.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 232.45 372.27 Td ( ) Tj ET Q q 0 0 0 rg BT 235.76 372.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 274.05 372.27 Td (of ) Tj ET Q q 0 0 0 rg BT 285.69 372.27 Td (an ) Tj ET Q q 0 0 0 rg BT 298.44 372.27 Td (expanded ) Tj ET Q q 0 0 0 rg BT 340.06 372.27 Td (indication ) Tj ET Q q 0 0 0 rg BT 383.36 372.27 Td (for ) Tj ET Q q 0 0 0 rg BT 398.32 372.27 Td (the ) Tj ET Q q 0 0 0 rg BT 413.85 372.27 Td (treatment ) Tj ET Q q 0 0 0 rg BT 454.91 372.27 Td (of ) Tj ET Q q 0 0 0 rg BT 466.55 372.27 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 519.83 372.27 Td (or ) Tj ET Q q 0 0 0 rg BT 531.46 372.27 Td (metastatic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 362.27 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 257.15 362.27 Td (in ) Tj ET Q q 0 0 0 rg BT 267.43 362.27 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 304.91 362.27 Td (patients.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 60.15 337.38 Td (Hepatitis C) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.35 327.38 Td (Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 150.15 332.27 Td (April 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 347.27 Td (China ) Tj ET Q q 0 0 0 rg BT 242.01 347.27 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.46 347.27 Td ( ) Tj ET Q q 0 0 0 rg BT 266.58 347.27 Td (approval ) Tj ET Q q 0 0 0 rg BT 306.68 347.27 Td (of ) Tj ET Q q 0 0 0 rg BT 320.13 347.27 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 337.47 347.27 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.58 347.27 Td ( ) Tj ET Q q 0 0 0 rg BT 378.70 347.27 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 398.26 347.27 Td (Sunvepra) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.02 347.27 Td ( ) Tj ET Q q 0 0 0 rg BT 441.14 347.27 Td (regimen ) Tj ET Q q 0 0 0 rg BT 479.03 347.27 Td (for ) Tj ET Q q 0 0 0 rg BT 495.81 347.27 Td (treatment-naive ) Tj ET Q q 0 0 0 rg BT 563.67 347.27 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 337.27 Td (experienced ) Tj ET Q q 0 0 0 rg BT 264.52 337.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 298.84 337.27 Td (infected ) Tj ET Q q 0 0 0 rg BT 334.26 337.27 Td (with ) Tj ET Q q 0 0 0 rg BT 355.26 337.27 Td (genotype ) Tj ET Q q 0 0 0 rg BT 395.13 337.27 Td (1b ) Tj ET Q q 0 0 0 rg BT 408.35 337.27 Td (chronic ) Tj ET Q q 0 0 0 rg BT 441.55 337.27 Td (HCV) Tj ET Q q 0 0 0 rg BT 461.37 337.27 Td (. ) Tj ET Q q 0 0 0 rg BT 467.09 337.27 Td (In ) Tj ET Q q 0 0 0 rg BT 478.64 337.27 Td (addition, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 517.13 337.27 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.24 337.27 Td ( ) Tj ET Q q 0 0 0 rg BT 556.46 337.27 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 327.27 Td (approved ) Tj ET Q q 0 0 0 rg BT 253.13 327.27 Td (in ) Tj ET Q q 0 0 0 rg BT 263.82 327.27 Td (China ) Tj ET Q q 0 0 0 rg BT 290.63 327.27 Td (for ) Tj ET Q q 0 0 0 rg BT 305.21 327.27 Td (combination ) Tj ET Q q 0 0 0 rg BT 358.12 327.27 Td (use ) Tj ET Q q 0 0 0 rg BT 374.37 327.27 Td (with ) Tj ET Q q 0 0 0 rg BT 395.06 327.27 Td (other ) Tj ET Q q 0 0 0 rg BT 418.53 327.27 Td (agents, ) Tj ET Q q 0 0 0 rg BT 449.50 327.27 Td (including ) Tj ET Q q 0 0 0 rg BT 490.19 327.27 Td (sofosbuvir) Tj ET Q q 0 0 0 rg BT 532.01 327.27 Td (, ) Tj ET Q q 0 0 0 rg BT 537.43 327.27 Td (for ) Tj ET Q q 0 0 0 rg BT 552.01 327.27 Td (adult ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.00 317.27 Td (patients ) Tj ET Q q 0 0 0 rg BT 246.60 317.27 Td (with ) Tj ET Q q 0 0 0 rg BT 266.88 317.27 Td (HCV) Tj ET Q q 0 0 0 rg BT 287.81 317.27 Td ( ) Tj ET Q q 0 0 0 rg BT 290.31 317.27 Td (genotypes ) Tj ET Q q 0 0 0 rg BT 333.36 317.27 Td (1-6 ) Tj ET Q q 0 0 0 rg BT 349.19 317.27 Td (infection.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 295.65 Td (Refer to "—Product and Pipeline Developments" for all of the developments in our marketed products and late-stage pipeline in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.97 295.65 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 570.97 295.65 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 283.65 Td (and in early 2018. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 259.65 Td (Strategy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 235.65 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.25 235.65 Td (focus ) Tj ET Q q 0 0 0 rg BT 76.60 235.65 Td (as ) Tj ET Q q 0 0 0 rg BT 86.63 235.65 Td (a ) Tj ET Q q 0 0 0 rg BT 92.76 235.65 Td (specialty ) Tj ET Q q 0 0 0 rg BT 129.99 235.65 Td (biopharmaceutical ) Tj ET Q q 0 0 0 rg BT 205.54 235.65 Td (company ) Tj ET Q q 0 0 0 rg BT 243.89 235.65 Td (is ) Tj ET Q q 0 0 0 rg BT 252.25 235.65 Td (on ) Tj ET Q q 0 0 0 rg BT 263.95 235.65 Td (discovering, ) Tj ET Q q 0 0 0 rg BT 314.80 235.65 Td (developing ) Tj ET Q q 0 0 0 rg BT 360.93 235.65 Td (and ) Tj ET Q q 0 0 0 rg BT 377.06 235.65 Td (delivering ) Tj ET Q q 0 0 0 rg BT 419.30 235.65 Td (transformational ) Tj ET Q q 0 0 0 rg BT 487.08 235.65 Td (medicines ) Tj ET Q q 0 0 0 rg BT 529.32 235.65 Td (that ) Tj ET Q q 0 0 0 rg BT 546.00 235.65 Td (address ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 223.65 Td (serious ) Tj ET Q q 0 0 0 rg BT 66.53 223.65 Td (unmet ) Tj ET Q q 0 0 0 rg BT 93.73 223.65 Td (medical ) Tj ET Q q 0 0 0 rg BT 127.59 223.65 Td (needs. ) Tj ET Q q 0 0 0 rg BT 155.06 223.65 Td (Our ) Tj ET Q q 0 0 0 rg BT 172.82 223.65 Td (strategy ) Tj ET Q q 0 0 0 rg BT 206.68 223.65 Td (is ) Tj ET Q q 0 0 0 rg BT 215.55 223.65 Td (to ) Tj ET Q q 0 0 0 rg BT 225.54 223.65 Td (combine ) Tj ET Q q 0 0 0 rg BT 262.17 223.65 Td (the ) Tj ET Q q 0 0 0 rg BT 276.60 223.65 Td (resources, ) Tj ET Q q 0 0 0 rg BT 319.06 223.65 Td (scale ) Tj ET Q q 0 0 0 rg BT 341.25 223.65 Td (and ) Tj ET Q q 0 0 0 rg BT 357.89 223.65 Td (capability ) Tj ET Q q 0 0 0 rg BT 399.53 223.65 Td (of ) Tj ET Q q 0 0 0 rg BT 410.06 223.65 Td (a ) Tj ET Q q 0 0 0 rg BT 416.70 223.65 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 479.98 223.65 Td (company ) Tj ET Q q 0 0 0 rg BT 518.84 223.65 Td (with ) Tj ET Q q 0 0 0 rg BT 538.82 223.65 Td (the ) Tj ET Q q 0 0 0 rg BT 553.25 223.65 Td (speed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 211.65 Td (and ) Tj ET Q q 0 0 0 rg BT 52.35 211.65 Td (focus ) Tj ET Q q 0 0 0 rg BT 75.93 211.65 Td (on ) Tj ET Q q 0 0 0 rg BT 87.85 211.65 Td (innovation ) Tj ET Q q 0 0 0 rg BT 132.54 211.65 Td (of ) Tj ET Q q 0 0 0 rg BT 142.78 211.65 Td (the ) Tj ET Q q 0 0 0 rg BT 156.92 211.65 Td (biotech ) Tj ET Q q 0 0 0 rg BT 188.27 211.65 Td (industry) Tj ET Q q 0 0 0 rg BT 220.40 211.65 Td (. ) Tj ET Q q 0 0 0 rg BT 224.81 211.65 Td (Our ) Tj ET Q q 0 0 0 rg BT 242.28 211.65 Td (four ) Tj ET Q q 0 0 0 rg BT 260.86 211.65 Td (strategic ) Tj ET Q q 0 0 0 rg BT 296.65 211.65 Td (priorities ) Tj ET Q q 0 0 0 rg BT 334.67 211.65 Td (are ) Tj ET Q q 0 0 0 rg BT 348.79 211.65 Td (to ) Tj ET Q q 0 0 0 rg BT 358.49 211.65 Td (drive ) Tj ET Q q 0 0 0 rg BT 380.95 211.65 Td (business ) Tj ET Q q 0 0 0 rg BT 416.76 211.65 Td (performance, ) Tj ET Q q 0 0 0 rg BT 471.70 211.65 Td (continue ) Tj ET Q q 0 0 0 rg BT 508.05 211.65 Td (to ) Tj ET Q q 0 0 0 rg BT 517.74 211.65 Td (build ) Tj ET Q q 0 0 0 rg BT 540.21 211.65 Td (a ) Tj ET Q q 0 0 0 rg BT 546.57 211.65 Td (leading ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 199.65 Td (franchise ) Tj ET Q q 0 0 0 rg BT 74.56 199.65 Td (in ) Tj ET Q q 0 0 0 rg BT 84.25 199.65 Td (IO, ) Tj ET Q q 0 0 0 rg BT 99.21 199.65 Td (maintain ) Tj ET Q q 0 0 0 rg BT 136.11 199.65 Td (a ) Tj ET Q q 0 0 0 rg BT 142.46 199.65 Td (diversified ) Tj ET Q q 0 0 0 rg BT 187.13 199.65 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 224.04 199.65 Td (both ) Tj ET Q q 0 0 0 rg BT 243.73 199.65 Td (within ) Tj ET Q q 0 0 0 rg BT 271.19 199.65 Td (and ) Tj ET Q q 0 0 0 rg BT 287.54 199.65 Td (outside ) Tj ET Q q 0 0 0 rg BT 318.34 199.65 Td (of ) Tj ET Q q 0 0 0 rg BT 328.58 199.65 Td (IO, ) Tj ET Q q 0 0 0 rg BT 343.54 199.65 Td (and ) Tj ET Q q 0 0 0 rg BT 359.89 199.65 Td (continue ) Tj ET Q q 0 0 0 rg BT 396.24 199.65 Td (our ) Tj ET Q q 0 0 0 rg BT 411.48 199.65 Td (disciplined ) Tj ET Q q 0 0 0 rg BT 457.27 199.65 Td (approach ) Tj ET Q q 0 0 0 rg BT 495.83 199.65 Td (to ) Tj ET Q q 0 0 0 rg BT 505.52 199.65 Td (capital ) Tj ET Q q 0 0 0 rg BT 534.08 199.65 Td (allocation, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 187.65 Td (including ) Tj ET Q q 0 0 0 rg BT 76.63 187.65 Td (establishing ) Tj ET Q q 0 0 0 rg BT 127.25 187.65 Td (partnerships, ) Tj ET Q q 0 0 0 rg BT 181.48 187.65 Td (collaborations ) Tj ET Q q 0 0 0 rg BT 240.98 187.65 Td (and ) Tj ET Q q 0 0 0 rg BT 258.27 187.65 Td (in-licensing ) Tj ET Q q 0 0 0 rg BT 308.33 187.65 Td (or ) Tj ET Q q 0 0 0 rg BT 319.52 187.65 Td (acquiring ) Tj ET Q q 0 0 0 rg BT 360.13 187.65 Td (investigational ) Tj ET Q q 0 0 0 rg BT 421.86 187.65 Td (compounds ) Tj ET Q q 0 0 0 rg BT 470.82 187.65 Td (as ) Tj ET Q q 0 0 0 rg BT 482.00 187.65 Td (an ) Tj ET Q q 0 0 0 rg BT 494.29 187.65 Td (essential ) Tj ET Q q 0 0 0 rg BT 531.58 187.65 Td (component ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 175.65 Td (of ) Tj ET Q q 0 0 0 rg BT 46.83 175.65 Td (successfully ) Tj ET Q q 0 0 0 rg BT 98.21 175.65 Td (delivering ) Tj ET Q q 0 0 0 rg BT 141.25 175.65 Td (transformational ) Tj ET Q q 0 0 0 rg BT 209.84 175.65 Td (medicines ) Tj ET Q q 0 0 0 rg BT 252.88 175.65 Td (to ) Tj ET Q q 0 0 0 rg BT 263.16 175.65 Td (patients.) Tj ET Q endstream endobj 63 0 obj <> endobj 64 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 749.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.82 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 66.77 749.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 113.95 749.10 Td (new ) Tj ET Q q 0 0 0 rg BT 133.35 749.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 176.63 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 187.16 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 202.12 749.10 Td (following ) Tj ET Q q 0 0 0 rg BT 243.75 749.10 Td (core ) Tj ET Q q 0 0 0 rg BT 263.70 749.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 310.86 749.10 Td (areas: ) Tj ET Q q 0 0 0 rg BT 336.92 749.10 Td (\(1\) ) Tj ET Q q 0 0 0 rg BT 351.32 749.10 Td (oncology ) Tj ET Q q 0 0 0 rg BT 391.28 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 411.80 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 418.98 749.10 Td (priority ) Tj ET Q q 0 0 0 rg BT 451.72 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 462.24 749.10 Td (IO; ) Tj ET Q q 0 0 0 rg BT 478.32 749.10 Td (\(2\) ) Tj ET Q q 0 0 0 rg BT 492.72 749.10 Td (immunoscience ) Tj ET Q q 0 0 0 rg BT 558.22 749.10 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (priorities ) Tj ET Q q 0 0 0 rg BT 73.85 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 83.38 737.10 Td (lupus, ) Tj ET Q q 0 0 0 rg BT 109.30 737.10 Td (rheumatoid ) Tj ET Q q 0 0 0 rg BT 156.59 737.10 Td (arthritis ) Tj ET Q q 0 0 0 rg BT 189.44 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 205.62 737.10 Td (inflammatory ) Tj ET Q q 0 0 0 rg BT 261.80 737.10 Td (bowel ) Tj ET Q q 0 0 0 rg BT 287.99 737.10 Td (disease; ) Tj ET Q q 0 0 0 rg BT 321.39 737.10 Td (\(3\) ) Tj ET Q q 0 0 0 rg BT 334.80 737.10 Td (cardiovascular ) Tj ET Q q 0 0 0 rg BT 394.85 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 414.37 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 420.56 737.10 Td (priority ) Tj ET Q q 0 0 0 rg BT 452.30 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 461.83 737.10 Td (heart ) Tj ET Q q 0 0 0 rg BT 483.56 737.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 514.19 737.10 Td (and; ) Tj ET Q q 0 0 0 rg BT 533.15 737.10 Td (\(4\) ) Tj ET Q q 0 0 0 rg BT 546.56 737.10 Td (fibrotic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 67.25 725.10 Td (with ) Tj ET Q q 0 0 0 rg BT 87.39 725.10 Td (priorities ) Tj ET Q q 0 0 0 rg BT 125.86 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 136.01 725.10 Td (lung ) Tj ET Q q 0 0 0 rg BT 156.16 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 172.96 725.10 Td (liver) Tj ET Q q 0 0 0 rg BT 190.74 725.10 Td (. ) Tj ET Q q 0 0 0 rg BT 195.43 725.10 Td (W) Tj ET Q q 0 0 0 rg BT 204.07 725.10 Td (e ) Tj ET Q q 0 0 0 rg BT 210.88 725.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 247.68 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 257.83 725.10 Td (advance ) Tj ET Q q 0 0 0 rg BT 292.95 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 307.53 725.10 Td (next ) Tj ET Q q 0 0 0 rg BT 327.12 725.10 Td (wave ) Tj ET Q q 0 0 0 rg BT 350.58 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 361.28 725.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 405.86 725.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 448.77 725.10 Td (by ) Tj ET Q q 0 0 0 rg BT 461.14 725.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 500.17 725.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 552.53 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 562.68 725.10 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 70.46 713.10 Td (both ) Tj ET Q q 0 0 0 rg BT 90.48 713.10 Td (internally ) Tj ET Q q 0 0 0 rg BT 131.05 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 147.73 713.10 Td (through ) Tj ET Q q 0 0 0 rg BT 181.08 713.10 Td (business ) Tj ET Q q 0 0 0 rg BT 217.22 713.10 Td (developments ) Tj ET Q q 0 0 0 rg BT 275.01 713.10 Td (activities. ) Tj ET Q q 0 0 0 rg BT 315.85 713.10 Td (In ) Tj ET Q q 0 0 0 rg BT 326.43 713.10 Td (IO, ) Tj ET Q q 0 0 0 rg BT 341.72 713.10 Td (we ) Tj ET Q q 0 0 0 rg BT 355.63 713.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 392.31 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 402.33 713.10 Td (invest ) Tj ET Q q 0 0 0 rg BT 428.46 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 438.49 713.10 Td (monotherapy ) Tj ET Q q 0 0 0 rg BT 493.49 713.10 Td (studies, ) Tj ET Q q 0 0 0 rg BT 526.02 713.10 Td (combination ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (approaches, ) Tj ET Q q 0 0 0 rg BT 86.14 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 103.25 701.10 Td (our ) Tj ET Q q 0 0 0 rg BT 119.25 701.10 Td (next ) Tj ET Q q 0 0 0 rg BT 139.13 701.10 Td (wave ) Tj ET Q q 0 0 0 rg BT 162.90 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 173.89 701.10 Td (early ) Tj ET Q q 0 0 0 rg BT 196.55 701.10 Td (assets. ) Tj ET Q q 0 0 0 rg BT 224.85 701.10 Td (W) Tj ET Q q 0 0 0 rg BT 233.49 701.10 Td (e ) Tj ET Q q 0 0 0 rg BT 240.60 701.10 Td (have ) Tj ET Q q 0 0 0 rg BT 262.14 701.10 Td (entered ) Tj ET Q q 0 0 0 rg BT 294.23 701.10 Td (into ) Tj ET Q q 0 0 0 rg BT 312.46 701.10 Td (several ) Tj ET Q q 0 0 0 rg BT 343.44 701.10 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 398.86 701.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 447.06 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 464.17 701.10 Td (expanded ) Tj ET Q q 0 0 0 rg BT 505.15 701.10 Td (others ) Tj ET Q q 0 0 0 rg BT 532.26 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 542.71 701.10 Td (research ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.89 689.10 Td (develop ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 89.00 689.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 118.44 689.10 Td ( ) Tj ET Q q 0 0 0 rg BT 121.89 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 139.79 689.10 Td (other ) Tj ET Q q 0 0 0 rg BT 163.79 689.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 204.45 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 216.23 689.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 278.56 689.10 Td (oncology ) Tj ET Q q 0 0 0 rg BT 319.23 689.10 Td (agents ) Tj ET Q q 0 0 0 rg BT 348.23 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 359.46 689.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 412.91 689.10 Td (regimens. ) Tj ET Q q 0 0 0 rg BT 455.27 689.10 Td (W) Tj ET Q q 0 0 0 rg BT 463.90 689.10 Td (e ) Tj ET Q q 0 0 0 rg BT 471.80 689.10 Td (remain ) Tj ET Q q 0 0 0 rg BT 503.01 689.10 Td (focused ) Tj ET Q q 0 0 0 rg BT 537.57 689.10 Td (and ) Tj ET Q q 0 0 0 rg BT 555.46 689.10 Td (well-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (resourced ) Tj ET Q q 0 0 0 rg BT 76.93 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 86.76 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 102.15 677.10 Td (cancer ) Tj ET Q q 0 0 0 rg BT 130.29 677.10 Td (development ) Tj ET Q q 0 0 0 rg BT 184.00 677.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 223.83 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 240.32 677.10 Td (seek ) Tj ET Q q 0 0 0 rg BT 260.15 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 269.99 677.10 Td (broaden ) Tj ET Q q 0 0 0 rg BT 304.25 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 318.53 677.10 Td (use ) Tj ET Q q 0 0 0 rg BT 333.92 677.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 344.30 677.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.74 677.10 Td ( ) Tj ET Q q 0 0 0 rg BT 375.80 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 385.64 677.10 Td (earlier ) Tj ET Q q 0 0 0 rg BT 413.23 677.10 Td (lines ) Tj ET Q q 0 0 0 rg BT 434.17 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 444.56 677.10 Td (therapy) Tj ET Q q 0 0 0 rg BT 473.90 677.10 Td (, ) Tj ET Q q 0 0 0 rg BT 478.45 677.10 Td (expand ) Tj ET Q q 0 0 0 rg BT 509.39 677.10 Td (into ) Tj ET Q q 0 0 0 rg BT 527.00 677.10 Td (new ) Tj ET Q q 0 0 0 rg BT 545.72 677.10 Td (tumors, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (accelerate ) Tj ET Q q 0 0 0 rg BT 78.58 665.10 Td (next ) Tj ET Q q 0 0 0 rg BT 98.43 665.10 Td (wave ) Tj ET Q q 0 0 0 rg BT 122.16 665.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 135.34 665.10 Td (mechanisms ) Tj ET Q q 0 0 0 rg BT 187.40 665.10 Td (and ) Tj ET Q q 0 0 0 rg BT 204.47 665.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 238.75 665.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 279.14 665.10 Td (options ) Tj ET Q q 0 0 0 rg BT 311.21 665.10 Td (for ) Tj ET Q q 0 0 0 rg BT 325.50 665.10 Td (refractory ) Tj ET Q q 0 0 0 rg BT 367.54 665.10 Td (IO ) Tj ET Q q 0 0 0 rg BT 380.72 665.10 Td (patients. ) Tj ET Q q 0 0 0 rg BT 416.96 665.10 Td (Beyond ) Tj ET Q q 0 0 0 rg BT 450.69 665.10 Td (cancer) Tj ET Q q 0 0 0 rg BT 476.38 665.10 Td (, ) Tj ET Q q 0 0 0 rg BT 481.51 665.10 Td (we ) Tj ET Q q 0 0 0 rg BT 495.79 665.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 532.86 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 543.26 665.10 Td (advance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (our ) Tj ET Q q 0 0 0 rg BT 51.55 653.10 Td (early ) Tj ET Q q 0 0 0 rg BT 73.76 653.10 Td (stage ) Tj ET Q q 0 0 0 rg BT 96.53 653.10 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 133.75 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 143.75 653.10 Td (immunoscience, ) Tj ET Q q 0 0 0 rg BT 211.23 653.10 Td (cardiovascular) Tj ET Q q 0 0 0 rg BT 269.13 653.10 Td (, ) Tj ET Q q 0 0 0 rg BT 273.86 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 290.52 653.10 Td (fibrotic ) Tj ET Q q 0 0 0 rg BT 322.18 653.10 Td (diseases ) Tj ET Q q 0 0 0 rg BT 357.17 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 373.83 653.10 Td (strengthen ) Tj ET Q q 0 0 0 rg BT 417.71 653.10 Td (our ) Tj ET Q q 0 0 0 rg BT 433.26 653.10 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 484.36 653.10 Td (with ) Tj ET Q q 0 0 0 rg BT 504.36 653.10 Td (a ) Tj ET Q q 0 0 0 rg BT 511.02 653.10 Td (diverse ) Tj ET Q q 0 0 0 rg BT 542.12 653.10 Td (group ) Tj ET Q q 0 0 0 rg BT 567.68 653.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 81.35 641.10 Td (and ) Tj ET Q q 0 0 0 rg BT 98.37 641.10 Td (academic ) Tj ET Q q 0 0 0 rg BT 138.70 641.10 Td (institutions ) Tj ET Q q 0 0 0 rg BT 185.73 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 196.09 641.10 Td (new ) Tj ET Q q 0 0 0 rg BT 215.33 641.10 Td (and ) Tj ET Q q 0 0 0 rg BT 232.36 641.10 Td (expanded ) Tj ET Q q 0 0 0 rg BT 273.25 641.10 Td (research ) Tj ET Q q 0 0 0 rg BT 309.14 641.10 Td (activities. ) Tj ET Q q 0 0 0 rg BT 350.13 641.10 Td (W) Tj ET Q q 0 0 0 rg BT 358.77 641.10 Td (e ) Tj ET Q q 0 0 0 rg BT 365.79 641.10 Td (believe ) Tj ET Q q 0 0 0 rg BT 397.25 641.10 Td (our ) Tj ET Q q 0 0 0 rg BT 413.16 641.10 Td (dif) Tj ET Q q 0 0 0 rg BT 424.09 641.10 Td (ferentiated ) Tj ET Q q 0 0 0 rg BT 469.42 641.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 502.54 641.10 Td (and ) Tj ET Q q 0 0 0 rg BT 519.56 641.10 Td (external ) Tj ET Q q 0 0 0 rg BT 554.35 641.10 Td (focus ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (contributes ) Tj ET Q q 0 0 0 rg BT 82.93 629.10 Td (to ) Tj ET Q q 0 0 0 rg BT 93.21 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 107.93 629.10 Td (advancing ) Tj ET Q q 0 0 0 rg BT 151.52 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 162.35 629.10 Td (our ) Tj ET Q q 0 0 0 rg BT 178.18 629.10 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 212.89 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 223.72 629.10 Td (potentially ) Tj ET Q q 0 0 0 rg BT 268.99 629.10 Td (transformational ) Tj ET Q q 0 0 0 rg BT 337.58 629.10 Td (medicines.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 607.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.47 607.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 102.59 607.50 Td (model ) Tj ET Q q 0 0 0 rg BT 129.51 607.50 Td (has ) Tj ET Q q 0 0 0 rg BT 144.77 607.50 Td (been ) Tj ET Q q 0 0 0 rg BT 165.57 607.50 Td (evolving ) Tj ET Q q 0 0 0 rg BT 202.48 607.50 Td (and ) Tj ET Q q 0 0 0 rg BT 218.84 607.50 Td (revenues ) Tj ET Q q 0 0 0 rg BT 256.30 607.50 Td (from ) Tj ET Q q 0 0 0 rg BT 277.67 607.50 Td (our ) Tj ET Q q 0 0 0 rg BT 292.92 607.50 Td (marketed ) Tj ET Q q 0 0 0 rg BT 332.04 607.50 Td (product ) Tj ET Q q 0 0 0 rg BT 364.51 607.50 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 401.43 607.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 437.79 607.50 Td (to ) Tj ET Q q 0 0 0 rg BT 447.49 607.50 Td (grow ) Tj ET Q q 0 0 0 rg BT 469.96 607.50 Td (which ) Tj ET Q q 0 0 0 rg BT 496.33 607.50 Td (demonstrates ) Tj ET Q q 0 0 0 rg BT 551.01 607.50 Td (strong ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 595.50 Td (execution ) Tj ET Q q 0 0 0 rg BT 77.88 595.50 Td (of ) Tj ET Q q 0 0 0 rg BT 89.22 595.50 Td (our ) Tj ET Q q 0 0 0 rg BT 105.56 595.50 Td (strategy) Tj ET Q q 0 0 0 rg BT 136.57 595.50 Td (. ) Tj ET Q q 0 0 0 rg BT 141.86 595.50 Td (W) Tj ET Q q 0 0 0 rg BT 150.50 595.50 Td (e ) Tj ET Q q 0 0 0 rg BT 157.94 595.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 195.39 595.50 Td (to ) Tj ET Q q 0 0 0 rg BT 206.17 595.50 Td (drive ) Tj ET Q q 0 0 0 rg BT 229.73 595.50 Td (growth ) Tj ET Q q 0 0 0 rg BT 261.07 595.50 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 272.41 595.50 Td (Opdivo ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.86 595.50 Td (by ) Tj ET Q q 0 0 0 rg BT 317.87 595.50 Td (expanding ) Tj ET Q q 0 0 0 rg BT 362.53 595.50 Td (into ) Tj ET Q q 0 0 0 rg BT 381.10 595.50 Td (additional ) Tj ET Q q 0 0 0 rg BT 424.10 595.50 Td (indications ) Tj ET Q q 0 0 0 rg BT 470.99 595.50 Td (and ) Tj ET Q q 0 0 0 rg BT 488.43 595.50 Td (tumor ) Tj ET Q q 0 0 0 rg BT 515.33 595.50 Td (types ) Tj ET Q q 0 0 0 rg BT 539.45 595.50 Td (both ) Tj ET Q q 0 0 0 rg BT 560.24 595.50 Td (as ) Tj ET Q q 0 0 0 rg BT 571.57 595.50 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 583.50 Td (monotherapy ) Tj ET Q q 0 0 0 rg BT 90.96 583.50 Td (and ) Tj ET Q q 0 0 0 rg BT 107.59 583.50 Td (in ) Tj ET Q q 0 0 0 rg BT 117.57 583.50 Td (combination ) Tj ET Q q 0 0 0 rg BT 169.76 583.50 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 189.73 583.50 Td (Y) Tj ET Q q 0 0 0 rg BT 194.37 583.50 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 216.58 583.50 Td ( ) Tj ET Q q 0 0 0 rg BT 218.78 583.50 Td (and ) Tj ET Q q 0 0 0 rg BT 235.41 583.50 Td (other ) Tj ET Q q 0 0 0 rg BT 258.16 583.50 Td (anti-cancer ) Tj ET Q q 0 0 0 rg BT 304.76 583.50 Td (agents. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 335.00 583.50 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.34 583.50 Td ( ) Tj ET Q q 0 0 0 rg BT 365.54 583.50 Td (continues ) Tj ET Q q 0 0 0 rg BT 406.06 583.50 Td (to ) Tj ET Q q 0 0 0 rg BT 416.03 583.50 Td (grow) Tj ET Q q 0 0 0 rg BT 435.93 583.50 Td (, ) Tj ET Q q 0 0 0 rg BT 440.63 583.50 Td (leveraging ) Tj ET Q q 0 0 0 rg BT 485.03 583.50 Td (its ) Tj ET Q q 0 0 0 rg BT 496.67 583.50 Td (best ) Tj ET Q q 0 0 0 rg BT 514.98 583.50 Td (in ) Tj ET Q q 0 0 0 rg BT 524.95 583.50 Td (class ) Tj ET Q q 0 0 0 rg BT 546.59 583.50 Td (clinical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 571.50 Td (profile ) Tj ET Q q 0 0 0 rg BT 64.53 571.50 Td (and ) Tj ET Q q 0 0 0 rg BT 80.84 571.50 Td (extensive ) Tj ET Q q 0 0 0 rg BT 120.47 571.50 Td (real ) Tj ET Q q 0 0 0 rg BT 137.33 571.50 Td (world ) Tj ET Q q 0 0 0 rg BT 162.53 571.50 Td (data, ) Tj ET Q q 0 0 0 rg BT 183.56 571.50 Td (and ) Tj ET Q q 0 0 0 rg BT 199.87 571.50 Td (is ) Tj ET Q q 0 0 0 rg BT 208.41 571.50 Td (now ) Tj ET Q q 0 0 0 rg BT 227.50 571.50 Td (the ) Tj ET Q q 0 0 0 rg BT 241.59 571.50 Td (number ) Tj ET Q q 0 0 0 rg BT 274.01 571.50 Td (one ) Tj ET Q q 0 0 0 rg BT 290.32 571.50 Td (novel ) Tj ET Q q 0 0 0 rg BT 314.41 571.50 Td (oral ) Tj ET Q q 0 0 0 rg BT 331.83 571.50 Td (anticoagulant ) Tj ET Q q 0 0 0 rg BT 387.56 571.50 Td (in ) Tj ET Q q 0 0 0 rg BT 397.21 571.50 Td (total ) Tj ET Q q 0 0 0 rg BT 416.86 571.50 Td (prescriptions ) Tj ET Q q 0 0 0 rg BT 470.39 571.50 Td (in ) Tj ET Q q 0 0 0 rg BT 480.04 571.50 Td (the ) Tj ET Q q 0 0 0 rg BT 494.13 571.50 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 513.64 571.50 Td (W) Tj ET Q q 0 0 0 rg BT 522.28 571.50 Td (e ) Tj ET Q q 0 0 0 rg BT 528.59 571.50 Td (are ) Tj ET Q q 0 0 0 rg BT 542.67 571.50 Td (building ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 559.50 Td (on ) Tj ET Q q 0 0 0 rg BT 48.51 559.50 Td (the ) Tj ET Q q 0 0 0 rg BT 63.23 559.50 Td (continued ) Tj ET Q q 0 0 0 rg BT 105.17 559.50 Td (success ) Tj ET Q q 0 0 0 rg BT 137.67 559.50 Td (of ) Tj ET Q q 0 0 0 rg BT 148.51 559.50 Td (our ) Tj ET Q q 0 0 0 rg BT 164.34 559.50 Td (other ) Tj ET Q q 0 0 0 rg BT 187.40 559.50 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 231.56 559.50 Td (brands ) Tj ET Q q 0 0 0 rg BT 260.72 559.50 Td (and ) Tj ET Q q 0 0 0 rg BT 277.67 559.50 Td (remain ) Tj ET Q q 0 0 0 rg BT 307.94 559.50 Td (strongly ) Tj ET Q q 0 0 0 rg BT 343.23 559.50 Td (committed ) Tj ET Q q 0 0 0 rg BT 388.50 559.50 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 398.79 559.50 Td (Or) Tj ET Q q 0 0 0 rg BT 409.53 559.50 Td (encia ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.69 559.50 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 450.64 559.50 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.62 559.50 Td (. ) Tj ET Q q 0 0 0 rg BT 485.45 559.50 Td (Through ) Tj ET Q q 0 0 0 rg BT 522.40 559.50 Td (our ) Tj ET Q q 0 0 0 rg BT 538.23 559.50 Td (operating ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 547.50 Td (model ) Tj ET Q q 0 0 0 rg BT 63.50 547.50 Td (transformation, ) Tj ET Q q 0 0 0 rg BT 127.37 547.50 Td (our ) Tj ET Q q 0 0 0 rg BT 143.20 547.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 192.89 547.50 Td (infrastructure ) Tj ET Q q 0 0 0 rg BT 249.26 547.50 Td (is ) Tj ET Q q 0 0 0 rg BT 258.43 547.50 Td (uniquely ) Tj ET Q q 0 0 0 rg BT 295.92 547.50 Td (leveraged ) Tj ET Q q 0 0 0 rg BT 337.28 547.50 Td (for ) Tj ET Q q 0 0 0 rg BT 351.44 547.50 Td (potential ) Tj ET Q q 0 0 0 rg BT 388.93 547.50 Td (growth.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 523.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.78 523.50 Td (operating ) Tj ET Q q 0 0 0 rg BT 93.78 523.50 Td (model ) Tj ET Q q 0 0 0 rg BT 121.00 523.50 Td (continues ) Tj ET Q q 0 0 0 rg BT 161.56 523.50 Td (to ) Tj ET Q q 0 0 0 rg BT 171.57 523.50 Td (evolve ) Tj ET Q q 0 0 0 rg BT 200.46 523.50 Td (and ) Tj ET Q q 0 0 0 rg BT 217.13 523.50 Td (we ) Tj ET Q q 0 0 0 rg BT 231.02 523.50 Td (have ) Tj ET Q q 0 0 0 rg BT 252.13 523.50 Td (been ) Tj ET Q q 0 0 0 rg BT 273.24 523.50 Td (successful ) Tj ET Q q 0 0 0 rg BT 316.57 523.50 Td (in ) Tj ET Q q 0 0 0 rg BT 326.58 523.50 Td (focusing ) Tj ET Q q 0 0 0 rg BT 363.25 523.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 412.67 523.50 Td (and ) Tj ET Q q 0 0 0 rg BT 429.34 523.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 453.25 523.50 Td (resources ) Tj ET Q q 0 0 0 rg BT 493.24 523.50 Td (on ) Tj ET Q q 0 0 0 rg BT 505.47 523.50 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 549.35 523.50 Td (brands ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 511.50 Td (and ) Tj ET Q q 0 0 0 rg BT 52.09 511.50 Td (markets, ) Tj ET Q q 0 0 0 rg BT 87.89 511.50 Td (strengthening ) Tj ET Q q 0 0 0 rg BT 143.97 511.50 Td (our ) Tj ET Q q 0 0 0 rg BT 158.95 511.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 182.26 511.50 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 229.45 511.50 Td (in ) Tj ET Q q 0 0 0 rg BT 238.87 511.50 Td (tumor ) Tj ET Q q 0 0 0 rg BT 264.41 511.50 Td (biology) Tj ET Q q 0 0 0 rg BT 294.31 511.50 Td (, ) Tj ET Q q 0 0 0 rg BT 298.46 511.50 Td (patient ) Tj ET Q q 0 0 0 rg BT 327.32 511.50 Td (selection, ) Tj ET Q q 0 0 0 rg BT 367.01 511.50 Td (and ) Tj ET Q q 0 0 0 rg BT 383.09 511.50 Td (new ) Tj ET Q q 0 0 0 rg BT 401.40 511.50 Td (biomarkers, ) Tj ET Q q 0 0 0 rg BT 450.53 511.50 Td (delivering ) Tj ET Q q 0 0 0 rg BT 492.72 511.50 Td (leaner ) Tj ET Q q 0 0 0 rg BT 518.79 511.50 Td (administrative ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 499.50 Td (functions ) Tj ET Q q 0 0 0 rg BT 76.43 499.50 Td (and ) Tj ET Q q 0 0 0 rg BT 94.09 499.50 Td (streamlining ) Tj ET Q q 0 0 0 rg BT 147.30 499.50 Td (our ) Tj ET Q q 0 0 0 rg BT 163.84 499.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 225.37 499.50 Td (network ) Tj ET Q q 0 0 0 rg BT 261.36 499.50 Td (to ) Tj ET Q q 0 0 0 rg BT 272.35 499.50 Td (reflect ) Tj ET Q q 0 0 0 rg BT 301.10 499.50 Td (the ) Tj ET Q q 0 0 0 rg BT 316.53 499.50 Td (importance ) Tj ET Q q 0 0 0 rg BT 364.73 499.50 Td (of ) Tj ET Q q 0 0 0 rg BT 376.28 499.50 Td (biologics ) Tj ET Q q 0 0 0 rg BT 416.16 499.50 Td (in ) Tj ET Q q 0 0 0 rg BT 427.15 499.50 Td (our ) Tj ET Q q 0 0 0 rg BT 443.70 499.50 Td (current ) Tj ET Q q 0 0 0 rg BT 475.23 499.50 Td (and ) Tj ET Q q 0 0 0 rg BT 492.89 499.50 Td (future ) Tj ET Q q 0 0 0 rg BT 519.98 499.50 Td (portfolio. ) Tj ET Q q 0 0 0 rg BT 560.46 499.50 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 487.50 Td (evolution ) Tj ET Q q 0 0 0 rg BT 76.74 487.50 Td (in ) Tj ET Q q 0 0 0 rg BT 87.48 487.50 Td (our ) Tj ET Q q 0 0 0 rg BT 103.78 487.50 Td (operating ) Tj ET Q q 0 0 0 rg BT 144.51 487.50 Td (model ) Tj ET Q q 0 0 0 rg BT 172.47 487.50 Td (will ) Tj ET Q q 0 0 0 rg BT 191.00 487.50 Td (enable ) Tj ET Q q 0 0 0 rg BT 220.06 487.50 Td (us ) Tj ET Q q 0 0 0 rg BT 231.91 487.50 Td (to ) Tj ET Q q 0 0 0 rg BT 242.66 487.50 Td (deliver ) Tj ET Q q 0 0 0 rg BT 273.39 487.50 Td (the ) Tj ET Q q 0 0 0 rg BT 288.57 487.50 Td (necessary ) Tj ET Q q 0 0 0 rg BT 330.40 487.50 Td (strategic, ) Tj ET Q q 0 0 0 rg BT 369.74 487.50 Td (financial ) Tj ET Q q 0 0 0 rg BT 407.69 487.50 Td (and ) Tj ET Q q 0 0 0 rg BT 425.09 487.50 Td (operational ) Tj ET Q q 0 0 0 rg BT 473.04 487.50 Td (flexibility ) Tj ET Q q 0 0 0 rg BT 515.45 487.50 Td (to ) Tj ET Q q 0 0 0 rg BT 526.19 487.50 Td (invest ) Tj ET Q q 0 0 0 rg BT 553.04 487.50 Td (in ) Tj ET Q q 0 0 0 rg BT 563.79 487.50 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 475.50 Td (highest ) Tj ET Q q 0 0 0 rg BT 67.39 475.50 Td (priority ) Tj ET Q q 0 0 0 rg BT 99.88 475.50 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 155.16 475.50 Td (within ) Tj ET Q q 0 0 0 rg BT 183.21 475.50 Td (our ) Tj ET Q q 0 0 0 rg BT 199.04 475.50 Td (portfolio.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 451.50 Td (Looking ) Tj ET Q q 0 0 0 rg BT 72.10 451.50 Td (ahead, ) Tj ET Q q 0 0 0 rg BT 100.13 451.50 Td (we ) Tj ET Q q 0 0 0 rg BT 114.01 451.50 Td (will ) Tj ET Q q 0 0 0 rg BT 131.78 451.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 168.43 451.50 Td (to ) Tj ET Q q 0 0 0 rg BT 178.43 451.50 Td (implement ) Tj ET Q q 0 0 0 rg BT 223.41 451.50 Td (our ) Tj ET Q q 0 0 0 rg BT 238.96 451.50 Td (biopharma ) Tj ET Q q 0 0 0 rg BT 283.94 451.50 Td (strategy ) Tj ET Q q 0 0 0 rg BT 317.81 451.50 Td (by ) Tj ET Q q 0 0 0 rg BT 330.02 451.50 Td (driving ) Tj ET Q q 0 0 0 rg BT 361.13 451.50 Td (the ) Tj ET Q q 0 0 0 rg BT 375.56 451.50 Td (growth ) Tj ET Q q 0 0 0 rg BT 406.10 451.50 Td (of ) Tj ET Q q 0 0 0 rg BT 416.65 451.50 Td (key ) Tj ET Q q 0 0 0 rg BT 433.30 451.50 Td (brands, ) Tj ET Q q 0 0 0 rg BT 464.68 451.50 Td (executing ) Tj ET Q q 0 0 0 rg BT 505.77 451.50 Td (product ) Tj ET Q q 0 0 0 rg BT 538.53 451.50 Td (launches, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 439.50 Td (investing ) Tj ET Q q 0 0 0 rg BT 75.61 439.50 Td (in ) Tj ET Q q 0 0 0 rg BT 86.33 439.50 Td (our ) Tj ET Q q 0 0 0 rg BT 102.60 439.50 Td (diverse ) Tj ET Q q 0 0 0 rg BT 134.42 439.50 Td (and ) Tj ET Q q 0 0 0 rg BT 151.81 439.50 Td (innovative ) Tj ET Q q 0 0 0 rg BT 196.96 439.50 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 234.62 439.50 Td (aided ) Tj ET Q q 0 0 0 rg BT 259.21 439.50 Td (by ) Tj ET Q q 0 0 0 rg BT 272.16 439.50 Td (strategic ) Tj ET Q q 0 0 0 rg BT 308.97 439.50 Td (business ) Tj ET Q q 0 0 0 rg BT 345.81 439.50 Td (development, ) Tj ET Q q 0 0 0 rg BT 402.90 439.50 Td (focusing ) Tj ET Q q 0 0 0 rg BT 440.28 439.50 Td (on ) Tj ET Q q 0 0 0 rg BT 453.23 439.50 Td (prioritized ) Tj ET Q q 0 0 0 rg BT 497.82 439.50 Td (markets, ) Tj ET Q q 0 0 0 rg BT 534.92 439.50 Td (increasing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 427.50 Td (investments ) Tj ET Q q 0 0 0 rg BT 86.27 427.50 Td (in ) Tj ET Q q 0 0 0 rg BT 96.55 427.50 Td (our ) Tj ET Q q 0 0 0 rg BT 112.38 427.50 Td (biologics ) Tj ET Q q 0 0 0 rg BT 151.55 427.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 212.36 427.50 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 260.39 427.50 Td (and ) Tj ET Q q 0 0 0 rg BT 277.33 427.50 Td (maintaining ) Tj ET Q q 0 0 0 rg BT 327.60 427.50 Td (a ) Tj ET Q q 0 0 0 rg BT 334.54 427.50 Td (culture ) Tj ET Q q 0 0 0 rg BT 364.80 427.50 Td (of ) Tj ET Q q 0 0 0 rg BT 375.63 427.50 Td (continuous ) Tj ET Q q 0 0 0 rg BT 422.02 427.50 Td (improvement.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 403.50 Td (Acquisition ) Tj ET Q q 0 0 0 rg BT 87.40 403.50 Td (and ) Tj ET Q q 0 0 0 rg BT 106.02 403.50 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 149.09 403.50 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 387.50 Td (Acquisition ) Tj ET Q q 0 0 0 rg BT 84.74 387.50 Td (and ) Tj ET Q q 0 0 0 rg BT 101.25 387.50 Td (licensing ) Tj ET Q q 0 0 0 rg BT 139.43 387.50 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 195.37 387.50 Td (allow ) Tj ET Q q 0 0 0 rg BT 219.66 387.50 Td (us ) Tj ET Q q 0 0 0 rg BT 230.63 387.50 Td (to ) Tj ET Q q 0 0 0 rg BT 240.48 387.50 Td (focus ) Tj ET Q q 0 0 0 rg BT 264.22 387.50 Td (our ) Tj ET Q q 0 0 0 rg BT 279.62 387.50 Td (resources ) Tj ET Q q 0 0 0 rg BT 319.46 387.50 Td (behind ) Tj ET Q q 0 0 0 rg BT 348.75 387.50 Td (our ) Tj ET Q q 0 0 0 rg BT 364.15 387.50 Td (growth ) Tj ET Q q 0 0 0 rg BT 394.56 387.50 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 449.41 387.50 Td (that ) Tj ET Q q 0 0 0 rg BT 466.48 387.50 Td (drive ) Tj ET Q q 0 0 0 rg BT 489.10 387.50 Td (the ) Tj ET Q q 0 0 0 rg BT 503.39 387.50 Td (greatest ) Tj ET Q q 0 0 0 rg BT 536.56 387.50 Td (long-term ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 375.50 Td (value. ) Tj ET Q q 0 0 0 rg BT 63.24 375.50 Td (W) Tj ET Q q 0 0 0 rg BT 71.88 375.50 Td (e ) Tj ET Q q 0 0 0 rg BT 79.65 375.50 Td (are ) Tj ET Q q 0 0 0 rg BT 95.19 375.50 Td (focused ) Tj ET Q q 0 0 0 rg BT 129.62 375.50 Td (on ) Tj ET Q q 0 0 0 rg BT 142.95 375.50 Td (the ) Tj ET Q q 0 0 0 rg BT 158.49 375.50 Td (following ) Tj ET Q q 0 0 0 rg BT 200.71 375.50 Td (core ) Tj ET Q q 0 0 0 rg BT 221.25 375.50 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 269.00 375.50 Td (areas: ) Tj ET Q q 0 0 0 rg BT 295.64 375.50 Td (oncology) Tj ET Q q 0 0 0 rg BT 332.21 375.50 Td (, ) Tj ET Q q 0 0 0 rg BT 338.04 375.50 Td (including ) Tj ET Q q 0 0 0 rg BT 379.14 375.50 Td (IO, ) Tj ET Q q 0 0 0 rg BT 395.52 375.50 Td (immunoscience, ) Tj ET Q q 0 0 0 rg BT 464.11 375.50 Td (cardiovascular ) Tj ET Q q 0 0 0 rg BT 525.74 375.50 Td (and ) Tj ET Q q 0 0 0 rg BT 543.51 375.50 Td (fibrosis. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 363.50 Td (Significant ) Tj ET Q q 0 0 0 rg BT 81.48 363.50 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 136.94 363.50 Td (during ) Tj ET Q q 0 0 0 rg BT 164.64 363.50 Td (the ) Tj ET Q q 0 0 0 rg BT 178.46 363.50 Td (past ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 196.16 363.50 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 216.15 363.50 Td ( ) Tj ET Q q 0 0 0 rg BT 217.74 363.50 Td (years ) Tj ET Q q 0 0 0 rg BT 240.44 363.50 Td ( ) Tj ET Q q 0 0 0 rg BT 242.04 363.50 Td (are ) Tj ET Q q 0 0 0 rg BT 255.84 363.50 Td (summarized ) Tj ET Q q 0 0 0 rg BT 306.31 363.50 Td (below) Tj ET Q q 0 0 0 rg BT 330.10 363.50 Td (. ) Tj ET Q q 0 0 0 rg BT 334.19 363.50 Td (Refer ) Tj ET Q q 0 0 0 rg BT 358.00 363.50 Td (to ) Tj ET Q q 0 0 0 rg BT 367.37 363.50 Td ("Item ) Tj ET Q q 0 0 0 rg BT 391.38 363.50 Td (8. ) Tj ET Q q 0 0 0 rg BT 400.47 363.50 Td (Financial ) Tj ET Q q 0 0 0 rg BT 439.28 363.50 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.20 363.50 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.20 363.50 Td (. ) Tj ET Q q 0 0 0 rg BT 522.94 363.50 Td (Acquisitions, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 351.50 Td (Divestitures ) Tj ET Q q 0 0 0 rg BT 86.83 351.50 Td (and ) Tj ET Q q 0 0 0 rg BT 103.76 351.50 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 145.15 351.50 Td (Arrangements" ) Tj ET Q q 0 0 0 rg BT 208.37 351.50 Td (for ) Tj ET Q q 0 0 0 rg BT 222.53 351.50 Td (further ) Tj ET Q q 0 0 0 rg BT 252.24 351.50 Td (information. ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 333.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 58.13 333.50 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 314.1669921875 m 53.2216796875 314.1669921875 l s q 0 0 0 rg BT 36.00 315.50 Td (Ono) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 53.22 315.50 Td (: ) Tj ET Q q 0 0 0 rg BT 58.87 315.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 82.86 315.50 Td (acquired ) Tj ET Q q 0 0 0 rg BT 120.15 315.50 Td (an ) Tj ET Q q 0 0 0 rg BT 132.46 315.50 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 173.09 315.50 Td (license ) Tj ET Q q 0 0 0 rg BT 203.72 315.50 Td (to ) Tj ET Q q 0 0 0 rg BT 214.37 315.50 Td (develop ) Tj ET Q q 0 0 0 rg BT 248.90 315.50 Td (and ) Tj ET Q q 0 0 0 rg BT 266.20 315.50 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 327.92 315.50 Td (ONO-4578, ) Tj ET Q q 0 0 0 rg BT 378.29 315.50 Td (Ono’) Tj ET Q q 0 0 0 rg BT 398.29 315.50 Td (s ) Tj ET Q q 0 0 0 rg BT 405.05 315.50 Td (Prostaglandin ) Tj ET Q q 0 0 0 rg BT 462.91 315.50 Td (E2 ) Tj ET Q q 0 0 0 rg BT 476.89 315.50 Td (receptor ) Tj ET Q q 0 0 0 rg BT 512.51 315.50 Td (4 ) Tj ET Q q 0 0 0 rg BT 520.38 315.50 Td (antagonist ) Tj ET Q q 0 0 0 rg BT 564.35 315.50 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 303.50 Td (the ) Tj ET Q q 0 0 0 rg BT 51.01 303.50 Td (treatment ) Tj ET Q q 0 0 0 rg BT 91.55 303.50 Td (of ) Tj ET Q q 0 0 0 rg BT 102.67 303.50 Td (cancer) Tj ET Q q 0 0 0 rg BT 128.21 303.50 Td (. ) Tj ET Q q 0 0 0 rg BT 133.50 303.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 157.41 303.50 Td (acquired ) Tj ET Q q 0 0 0 rg BT 194.62 303.50 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 240.18 303.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 265.75 303.50 Td (except ) Tj ET Q q 0 0 0 rg BT 294.63 303.50 Td (in ) Tj ET Q q 0 0 0 rg BT 305.20 303.50 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 333.26 303.50 Td (South ) Tj ET Q q 0 0 0 rg BT 359.39 303.50 Td (Korea, ) Tj ET Q q 0 0 0 rg BT 389.10 303.50 Td (and ) Tj ET Q q 0 0 0 rg BT 406.13 303.50 Td (T) Tj ET Q q 0 0 0 rg BT 411.54 303.50 Td (aiwan ) Tj ET Q q 0 0 0 rg BT 438.21 303.50 Td (where ) Tj ET Q q 0 0 0 rg BT 465.43 303.50 Td (it ) Tj ET Q q 0 0 0 rg BT 473.77 303.50 Td (was ) Tj ET Q q 0 0 0 rg BT 492.11 303.50 Td (added ) Tj ET Q q 0 0 0 rg BT 518.78 303.50 Td (to ) Tj ET Q q 0 0 0 rg BT 529.35 303.50 Td (the ) Tj ET Q q 0 0 0 rg BT 544.35 303.50 Td (existing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 291.50 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 91.26 291.50 Td (and ) Tj ET Q q 0 0 0 rg BT 108.20 291.50 Td (in ) Tj ET Q q 0 0 0 rg BT 118.48 291.50 Td (China ) Tj ET Q q 0 0 0 rg BT 144.86 291.50 Td (and ) Tj ET Q q 0 0 0 rg BT 161.25 291.50 Td (ASEAN ) Tj ET Q q 0 0 0 rg BT 197.08 291.50 Td (countries ) Tj ET Q q 0 0 0 rg BT 236.24 291.50 Td (where ) Tj ET Q q 0 0 0 rg BT 263.17 291.50 Td (Ono ) Tj ET Q q 0 0 0 rg BT 282.89 291.50 Td (retained ) Tj ET Q q 0 0 0 rg BT 317.59 291.50 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 357.86 291.50 Td (rights.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 272.1669921875 m 77.09375 272.1669921875 l s q 0 0 0 rg BT 36.00 273.50 Td (Halozyme) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 77.09 273.50 Td (: ) Tj ET Q q 0 0 0 rg BT 82.03 273.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 105.32 273.50 Td (and ) Tj ET Q q 0 0 0 rg BT 121.92 273.50 Td (Halozyme ) Tj ET Q q 0 0 0 rg BT 165.18 273.50 Td (entered ) Tj ET Q q 0 0 0 rg BT 196.76 273.50 Td (into ) Tj ET Q q 0 0 0 rg BT 214.48 273.50 Td (a ) Tj ET Q q 0 0 0 rg BT 221.08 273.50 Td (global ) Tj ET Q q 0 0 0 rg BT 248.24 273.50 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 303.16 273.50 Td (and ) Tj ET Q q 0 0 0 rg BT 319.76 273.50 Td (license ) Tj ET Q q 0 0 0 rg BT 349.69 273.50 Td (agreement ) Tj ET Q q 0 0 0 rg BT 393.49 273.50 Td (to ) Tj ET Q q 0 0 0 rg BT 403.43 273.50 Td (develop ) Tj ET Q q 0 0 0 rg BT 437.25 273.50 Td (subcutaneously ) Tj ET Q q 0 0 0 rg BT 501.06 273.50 Td (administered ) Tj ET Q q 0 0 0 rg BT 554.88 273.50 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 261.50 Td (IO ) Tj ET Q q 0 0 0 rg BT 48.07 261.50 Td (medicines ) Tj ET Q q 0 0 0 rg BT 90.12 261.50 Td (using ) Tj ET Q q 0 0 0 rg BT 113.31 261.50 Td (Halozyme's ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 161.61 261.50 Td (ENHANZE) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.06 261.50 Td (* ) Tj ET Q q 0 0 0 rg BT 212.57 261.50 Td (drug-delivery ) Tj ET Q q 0 0 0 rg BT 268.51 261.50 Td (technology ) Tj ET Q q 0 0 0 rg BT 314.46 261.50 Td (which ) Tj ET Q q 0 0 0 rg BT 340.42 261.50 Td (may ) Tj ET Q q 0 0 0 rg BT 359.15 261.50 Td (allow ) Tj ET Q q 0 0 0 rg BT 382.88 261.50 Td (for ) Tj ET Q q 0 0 0 rg BT 396.06 261.50 Td (more ) Tj ET Q q 0 0 0 rg BT 418.12 261.50 Td (rapid ) Tj ET Q q 0 0 0 rg BT 440.18 261.50 Td (delivery ) Tj ET Q q 0 0 0 rg BT 474.46 261.50 Td (of ) Tj ET Q q 0 0 0 rg BT 484.30 261.50 Td (lar) Tj ET Q q 0 0 0 rg BT 494.67 261.50 Td (ge ) Tj ET Q q 0 0 0 rg BT 505.62 261.50 Td (volume ) Tj ET Q q 0 0 0 rg BT 537.13 261.50 Td (injectable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 249.50 Td (medications.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 230.1669921875 m 53.783203125 230.1669921875 l s q 0 0 0 rg BT 36.00 231.50 Td (IFM) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 53.78 231.50 Td (: ) Tj ET Q q 0 0 0 rg BT 58.67 231.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 81.91 231.50 Td (acquired ) Tj ET Q q 0 0 0 rg BT 118.44 231.50 Td (all ) Tj ET Q q 0 0 0 rg BT 130.55 231.50 Td (of ) Tj ET Q q 0 0 0 rg BT 140.99 231.50 Td (the ) Tj ET Q q 0 0 0 rg BT 155.32 231.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 204.10 231.50 Td (shares ) Tj ET Q q 0 0 0 rg BT 231.20 231.50 Td (of ) Tj ET Q q 0 0 0 rg BT 241.64 231.50 Td (IFM ) Tj ET Q q 0 0 0 rg BT 261.54 231.50 Td (providing ) Tj ET Q q 0 0 0 rg BT 302.54 231.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 325.77 231.50 Td (with ) Tj ET Q q 0 0 0 rg BT 345.66 231.50 Td (full ) Tj ET Q q 0 0 0 rg BT 361.66 231.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 386.55 231.50 Td (to ) Tj ET Q q 0 0 0 rg BT 396.44 231.50 Td (IFM's ) Tj ET Q q 0 0 0 rg BT 422.03 231.50 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 466.34 231.50 Td (STING ) Tj ET Q q 0 0 0 rg BT 497.89 231.50 Td (and ) Tj ET Q q 0 0 0 rg BT 514.44 231.50 Td (NLRP3 ) Tj ET Q q 0 0 0 rg BT 547.12 231.50 Td (agonist ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 219.50 Td (programs ) Tj ET Q q 0 0 0 rg BT 76.27 219.50 Td (focused ) Tj ET Q q 0 0 0 rg BT 109.87 219.50 Td (on ) Tj ET Q q 0 0 0 rg BT 122.37 219.50 Td (enhancing ) Tj ET Q q 0 0 0 rg BT 165.96 219.50 Td (the ) Tj ET Q q 0 0 0 rg BT 180.68 219.50 Td (innate ) Tj ET Q q 0 0 0 rg BT 207.61 219.50 Td (immune ) Tj ET Q q 0 0 0 rg BT 242.88 219.50 Td (response ) Tj ET Q q 0 0 0 rg BT 280.38 219.50 Td (for ) Tj ET Q q 0 0 0 rg BT 294.54 219.50 Td (treating ) Tj ET Q q 0 0 0 rg BT 327.58 219.50 Td (cancer) Tj ET Q q 0 0 0 rg BT 353.11 219.50 Td (. ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 200.1669921875 m 64.88671875 200.1669921875 l s q 0 0 0 rg BT 36.00 201.50 Td (Biogen) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 201.50 Td (: ) Tj ET Q q 0 0 0 rg BT 69.09 201.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 91.63 201.50 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 141.93 201.50 Td (to ) Tj ET Q q 0 0 0 rg BT 151.13 201.50 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 181.44 201.50 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 220.62 201.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 244.82 201.50 Td (to ) Tj ET Q q 0 0 0 rg BT 254.02 201.50 Td (develop ) Tj ET Q q 0 0 0 rg BT 287.10 201.50 Td (and ) Tj ET Q q 0 0 0 rg BT 302.96 201.50 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 363.24 201.50 Td (BMS-986168, ) Tj ET Q q 0 0 0 rg BT 421.61 201.50 Td (an ) Tj ET Q q 0 0 0 rg BT 432.47 201.50 Td (anti-eT) Tj ET Q q 0 0 0 rg BT 460.65 201.50 Td (au ) Tj ET Q q 0 0 0 rg BT 471.51 201.50 Td (compound ) Tj ET Q q 0 0 0 rg BT 515.15 201.50 Td (in ) Tj ET Q q 0 0 0 rg BT 524.35 201.50 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.50 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 189.50 Td (Progressive ) Tj ET Q q 0 0 0 rg BT 99.32 189.50 Td (Supranuclear ) Tj ET Q q 0 0 0 rg BT 154.57 189.50 Td (Palsy) Tj ET Q q 0 0 0 rg BT 175.59 189.50 Td (. ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 170.1669921875 m 61.546875 170.1669921875 l s q 0 0 0 rg BT 36.00 171.50 Td (Roche) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.55 171.50 Td (: ) Tj ET Q q 0 0 0 rg BT 68.94 171.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.69 171.50 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 148.18 171.50 Td (to ) Tj ET Q q 0 0 0 rg BT 160.57 171.50 Td (Roche ) Tj ET Q q 0 0 0 rg BT 190.74 171.50 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 233.12 171.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 260.52 171.50 Td (to ) Tj ET Q q 0 0 0 rg BT 272.92 171.50 Td (develop ) Tj ET Q q 0 0 0 rg BT 309.19 171.50 Td (and ) Tj ET Q q 0 0 0 rg BT 328.25 171.50 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 391.72 171.50 Td (BMS-986089, ) Tj ET Q q 0 0 0 rg BT 453.29 171.50 Td (an ) Tj ET Q q 0 0 0 rg BT 467.35 171.50 Td (anti-myostatin ) Tj ET Q q 0 0 0 rg BT 529.73 171.50 Td (adnectin ) Tj ET Q q 0 0 0 rg BT 568.22 171.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 159.50 Td (development ) Tj ET Q q 0 0 0 rg BT 90.15 159.50 Td (for ) Tj ET Q q 0 0 0 rg BT 104.31 159.50 Td (Duchenne ) Tj ET Q q 0 0 0 rg BT 147.35 159.50 Td (Muscular ) Tj ET Q q 0 0 0 rg BT 187.62 159.50 Td (Dystrophy) Tj ET Q q 0 0 0 rg BT 229.19 159.50 Td (. ) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 148.43 34.45 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 140.1669921875 m 70.4482421875 140.1669921875 l s q 0 0 0 rg BT 36.00 141.50 Td (CytomX) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 70.45 148.43 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 70.45 141.50 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 73.23 141.50 Td ( ) Tj ET Q q 0 0 0 rg BT 76.27 141.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 100.44 141.50 Td (and ) Tj ET Q q 0 0 0 rg BT 117.93 141.50 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 155.42 141.50 Td (expanded ) Tj ET Q q 0 0 0 rg BT 196.79 141.50 Td (their ) Tj ET Q q 0 0 0 rg BT 218.16 141.50 Td (initial ) Tj ET Q q 0 0 0 rg BT 244.54 141.50 Td (2014 ) Tj ET Q q 0 0 0 rg BT 267.58 141.50 Td (strategic ) Tj ET Q q 0 0 0 rg BT 304.50 141.50 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 360.31 141.50 Td (to ) Tj ET Q q 0 0 0 rg BT 371.13 141.50 Td (discover ) Tj ET Q q 0 0 0 rg BT 408.06 141.50 Td (novel ) Tj ET Q q 0 0 0 rg BT 433.32 141.50 Td (cancer ) Tj ET Q q 0 0 0 rg BT 462.45 141.50 Td (treatment ) Tj ET Q q 0 0 0 rg BT 503.26 141.50 Td (therapies ) Tj ET Q q 0 0 0 rg BT 542.40 141.50 Td (that ) Tj ET Q q 0 0 0 rg BT 560.44 141.50 Td (will ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 129.50 Td (include ) Tj ET Q q 0 0 0 rg BT 67.93 129.50 Td (up ) Tj ET Q q 0 0 0 rg BT 80.43 129.50 Td (to ) Tj ET Q q 0 0 0 rg BT 90.71 129.50 Td (eight ) Tj ET Q q 0 0 0 rg BT 113.21 129.50 Td (additional ) Tj ET Q q 0 0 0 rg BT 155.70 129.50 Td (tar) Tj ET Q q 0 0 0 rg BT 166.06 129.50 Td (gets ) Tj ET Q q 0 0 0 rg BT 184.67 129.50 Td (using ) Tj ET Q q 0 0 0 rg BT 208.84 129.50 Td (CytomX’) Tj ET Q q 0 0 0 rg BT 246.07 129.50 Td (s ) Tj ET Q q 0 0 0 rg BT 252.46 129.50 Td (proprietary ) Tj ET Q q 0 0 0 rg BT 299.38 129.50 Td (Probody ) Tj ET Q q 0 0 0 rg BT 335.78 129.50 Td (platform ) Tj ET Q q 0 0 0 rg BT 372.71 129.50 Td (for ) Tj ET Q q 0 0 0 rg BT 386.87 129.50 Td (the ) Tj ET Q q 0 0 0 rg BT 401.59 129.50 Td (treatment ) Tj ET Q q 0 0 0 rg BT 441.84 129.50 Td (of ) Tj ET Q q 0 0 0 rg BT 452.67 129.50 Td (cancer) Tj ET Q q 0 0 0 rg BT 478.21 129.50 Td (.) Tj ET Q endstream endobj 65 0 obj <> endobj 66 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (32) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (2016 ) Tj ET Q q 0 0 0 rg BT 58.13 749.25 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 738.18 33.34 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 729.9169921875 m 69.3447265625 729.9169921875 l s q 0 0 0 rg BT 36.00 731.25 Td (PsiOxus) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 69.34 738.18 5.22 -9.09 re f /GS0 gs q 0 0 0 rg BT 69.34 731.25 Td (: ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 74.57 731.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 98.14 731.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 135.01 731.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 175.21 731.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 220.43 731.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 245.65 731.25 Td (to ) Tj ET Q q 0 0 0 rg BT 255.88 731.25 Td (PsiOxus's ) Tj ET Q q 0 0 0 rg BT 297.36 731.25 Td (NG-348, ) Tj ET Q q 0 0 0 rg BT 335.08 731.25 Td (a ) Tj ET Q q 0 0 0 rg BT 341.96 731.25 Td (pre-clinical ) Tj ET Q q 0 0 0 rg BT 389.93 731.25 Td (stage, ) Tj ET Q q 0 0 0 rg BT 415.43 731.25 Td ("armed" ) Tj ET Q q 0 0 0 rg BT 451.02 731.25 Td (oncolytic ) Tj ET Q q 0 0 0 rg BT 490.68 731.25 Td (virus ) Tj ET Q q 0 0 0 rg BT 513.12 731.25 Td (with ) Tj ET Q q 0 0 0 rg BT 533.35 731.25 Td (the ) Tj ET Q q 0 0 0 rg BT 548.01 731.25 Td (goal ) Tj ET Q q 0 0 0 rg BT 567.67 731.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 719.25 Td (addressing ) Tj ET Q q 0 0 0 rg BT 81.27 719.25 Td (solid ) Tj ET Q q 0 0 0 rg BT 103.22 719.25 Td (tumors.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 708.18 32.22 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 699.9169921875 m 68.216796875 699.9169921875 l s q 0 0 0 rg BT 36.00 701.25 Td (Padlock) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 68.22 708.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 68.22 701.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 71.00 701.25 Td ( ) Tj ET Q q 0 0 0 rg BT 73.80 701.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 97.72 701.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 134.94 701.25 Td (all ) Tj ET Q q 0 0 0 rg BT 147.74 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 158.87 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 173.89 701.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 223.35 701.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 251.14 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 262.27 701.25 Td (Padlock ) Tj ET Q q 0 0 0 rg BT 297.29 701.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 338.98 701.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 362.90 701.25 Td (with ) Tj ET Q q 0 0 0 rg BT 383.48 701.25 Td (full ) Tj ET Q q 0 0 0 rg BT 400.17 701.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 425.74 701.25 Td (to ) Tj ET Q q 0 0 0 rg BT 436.32 701.25 Td (Padlock’) Tj ET Q q 0 0 0 rg BT 471.32 701.25 Td (s ) Tj ET Q q 0 0 0 rg BT 478.01 701.25 Td (P) Tj ET Q q 0 0 0 rg BT 482.65 701.25 Td (AD ) Tj ET Q q 0 0 0 rg BT 499.90 701.25 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 537.14 701.25 Td (discovery ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (program ) Tj ET Q q 0 0 0 rg BT 72.38 689.25 Td (focused ) Tj ET Q q 0 0 0 rg BT 105.98 689.25 Td (on ) Tj ET Q q 0 0 0 rg BT 118.48 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 133.19 689.25 Td (development ) Tj ET Q q 0 0 0 rg BT 187.34 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 198.17 689.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 238.43 689.25 Td (approaches ) Tj ET Q q 0 0 0 rg BT 285.91 689.25 Td (for ) Tj ET Q q 0 0 0 rg BT 300.07 689.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 333.67 689.25 Td (with ) Tj ET Q q 0 0 0 rg BT 353.95 689.25 Td (rheumatoid ) Tj ET Q q 0 0 0 rg BT 401.99 689.25 Td (arthritis.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 678.18 43.33 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 669.9169921875 m 79.3251953125 669.9169921875 l s q 0 0 0 rg BT 36.00 671.25 Td (Cormorant) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 79.33 678.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 79.33 671.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 82.10 671.25 Td ( ) Tj ET Q q 0 0 0 rg BT 85.34 671.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 109.70 671.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 147.37 671.25 Td (all ) Tj ET Q q 0 0 0 rg BT 160.60 671.25 Td (of ) Tj ET Q q 0 0 0 rg BT 172.17 671.25 Td (the ) Tj ET Q q 0 0 0 rg BT 187.63 671.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 237.53 671.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 265.76 671.25 Td (of ) Tj ET Q q 0 0 0 rg BT 277.33 671.25 Td (Cormorant ) Tj ET Q q 0 0 0 rg BT 323.89 671.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 366.02 671.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 390.38 671.25 Td (with ) Tj ET Q q 0 0 0 rg BT 411.40 671.25 Td (full ) Tj ET Q q 0 0 0 rg BT 428.52 671.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 454.54 671.25 Td (to ) Tj ET Q q 0 0 0 rg BT 465.55 671.25 Td (Cormorant's ) Tj ET Q q 0 0 0 rg BT 517.81 671.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 537.71 671.25 Td (candidate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 659.25 Td (HuMax-IL8, ) Tj ET Q q 0 0 0 rg BT 89.63 659.25 Td (a ) Tj ET Q q 0 0 0 rg BT 96.87 659.25 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 146.89 659.25 Td (antibody ) Tj ET Q q 0 0 0 rg BT 184.69 659.25 Td (that ) Tj ET Q q 0 0 0 rg BT 202.49 659.25 Td (represents ) Tj ET Q q 0 0 0 rg BT 245.84 659.25 Td (a ) Tj ET Q q 0 0 0 rg BT 253.08 659.25 Td (potentially ) Tj ET Q q 0 0 0 rg BT 298.66 659.25 Td (complementary ) Tj ET Q q 0 0 0 rg BT 363.66 659.25 Td (IO ) Tj ET Q q 0 0 0 rg BT 377.02 659.25 Td (mechanism ) Tj ET Q q 0 0 0 rg BT 425.37 659.25 Td (of ) Tj ET Q q 0 0 0 rg BT 436.51 659.25 Td (action ) Tj ET Q q 0 0 0 rg BT 463.75 659.25 Td (to ) Tj ET Q q 0 0 0 rg BT 474.13 659.25 Td (T) Tj ET Q q 0 0 0 rg BT 479.32 659.25 Td (-cell ) Tj ET Q q 0 0 0 rg BT 499.89 659.25 Td (directed ) Tj ET Q q 0 0 0 rg BT 534.90 659.25 Td (antibodies ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 647.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 647.25 Td (co-stimulatory ) Tj ET Q q 0 0 0 rg BT 113.76 647.25 Td (molecules.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 636.18 48.74 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 627.9169921875 m 84.744140625 627.9169921875 l s q 0 0 0 rg BT 36.00 629.25 Td (Nitto ) Tj ET Q q 0 0 0 rg BT 58.08 629.25 Td (Denko) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 84.74 636.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 84.74 629.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.52 629.25 Td ( ) Tj ET Q q 0 0 0 rg BT 89.05 629.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 111.70 629.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 147.65 629.25 Td (an ) Tj ET Q q 0 0 0 rg BT 158.62 629.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 197.91 629.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 242.20 629.25 Td (license ) Tj ET Q q 0 0 0 rg BT 271.50 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 280.80 629.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 313.98 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 329.95 629.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 390.33 629.25 Td (Nitto ) Tj ET Q q 0 0 0 rg BT 412.41 629.25 Td (Denko's ) Tj ET Q q 0 0 0 rg BT 446.29 629.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 506.70 629.25 Td (siRNA) Tj ET Q q 0 0 0 rg BT 533.93 629.25 Td ( ) Tj ET Q q 0 0 0 rg BT 535.46 629.25 Td (molecules ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (tar) Tj ET Q q 0 0 0 rg BT 46.37 617.25 Td (geting ) Tj ET Q q 0 0 0 rg BT 72.94 617.25 Td (heat ) Tj ET Q q 0 0 0 rg BT 91.18 617.25 Td (shock ) Tj ET Q q 0 0 0 rg BT 116.09 617.25 Td (protein ) Tj ET Q q 0 0 0 rg BT 146.00 617.25 Td (47 ) Tj ET Q q 0 0 0 rg BT 157.58 617.25 Td (\(HSP47\) ) Tj ET Q q 0 0 0 rg BT 194.17 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 203.53 617.25 Td (vitamin ) Tj ET Q q 0 0 0 rg BT 235.31 617.25 Td (A) Tj ET Q q 0 0 0 rg BT 241.98 617.25 Td ( ) Tj ET Q q 0 0 0 rg BT 243.57 617.25 Td (containing ) Tj ET Q q 0 0 0 rg BT 287.36 617.25 Td (formulations ) Tj ET Q q 0 0 0 rg BT 340.05 617.25 Td (including ) Tj ET Q q 0 0 0 rg BT 379.40 617.25 Td (Nitto ) Tj ET Q q 0 0 0 rg BT 401.54 617.25 Td (Denko's ) Tj ET Q q 0 0 0 rg BT 435.48 617.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 453.71 617.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 474.73 617.25 Td (ND-L02-s0201, ) Tj ET Q q 0 0 0 rg BT 539.92 617.25 Td (currently ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.47 605.25 Td (development ) Tj ET Q q 0 0 0 rg BT 100.80 605.25 Td (for ) Tj ET Q q 0 0 0 rg BT 115.15 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 130.06 605.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 170.50 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 181.52 605.25 Td (advanced ) Tj ET Q q 0 0 0 rg BT 221.96 605.25 Td (liver ) Tj ET Q q 0 0 0 rg BT 242.98 605.25 Td (fibrosis, ) Tj ET Q q 0 0 0 rg BT 278.17 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 295.29 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 310.20 605.25 Td (option ) Tj ET Q q 0 0 0 rg BT 338.44 605.25 Td (to ) Tj ET Q q 0 0 0 rg BT 348.91 605.25 Td (receive ) Tj ET Q q 0 0 0 rg BT 380.46 605.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 420.91 605.25 Td (licenses ) Tj ET Q q 0 0 0 rg BT 455.25 605.25 Td (for ) Tj ET Q q 0 0 0 rg BT 469.60 605.25 Td (HSP47 ) Tj ET Q q 0 0 0 rg BT 500.63 605.25 Td (siRNAs ) Tj ET Q q 0 0 0 rg BT 535.00 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 545.46 605.25 Td (vitamin ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 593.25 Td ( ) Tj ET Q q 0 0 0 rg BT 45.17 593.25 Td (containing ) Tj ET Q q 0 0 0 rg BT 89.88 593.25 Td (formulations ) Tj ET Q q 0 0 0 rg BT 143.49 593.25 Td (for ) Tj ET Q q 0 0 0 rg BT 157.65 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 172.36 593.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 212.62 593.25 Td (of ) Tj ET Q q 0 0 0 rg BT 223.45 593.25 Td (lung ) Tj ET Q q 0 0 0 rg BT 243.73 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 260.67 593.25 Td (other ) Tj ET Q q 0 0 0 rg BT 283.71 593.25 Td (or) Tj ET Q q 0 0 0 rg BT 291.86 593.25 Td (gan ) Tj ET Q q 0 0 0 rg BT 308.80 593.25 Td (fibrosis.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 575.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 58.13 575.25 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 564.18 26.67 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 555.9169921875 m 62.669921875 555.9169921875 l s q 0 0 0 rg BT 36.00 557.25 Td (Flexus) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 62.67 564.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 62.67 557.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 65.45 557.25 Td ( ) Tj ET Q q 0 0 0 rg BT 68.08 557.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 91.83 557.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 128.88 557.25 Td (all ) Tj ET Q q 0 0 0 rg BT 141.50 557.25 Td (of ) Tj ET Q q 0 0 0 rg BT 152.46 557.25 Td (the ) Tj ET Q q 0 0 0 rg BT 167.31 557.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 216.60 557.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 244.22 557.25 Td (of ) Tj ET Q q 0 0 0 rg BT 255.18 557.25 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 284.48 557.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 325.99 557.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 349.74 557.25 Td (with ) Tj ET Q q 0 0 0 rg BT 370.15 557.25 Td (full ) Tj ET Q q 0 0 0 rg BT 386.67 557.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 412.07 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 422.48 557.25 Td (F001287, ) Tj ET Q q 0 0 0 rg BT 463.17 557.25 Td (a ) Tj ET Q q 0 0 0 rg BT 470.24 557.25 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 515.06 557.25 Td (small ) Tj ET Q q 0 0 0 rg BT 539.35 557.25 Td (molecule ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (IDO1-inhibitor ) Tj ET Q q 0 0 0 rg BT 99.11 545.25 Td (tar) Tj ET Q q 0 0 0 rg BT 109.48 545.25 Td (geted ) Tj ET Q q 0 0 0 rg BT 133.70 545.25 Td (immunotherapy ) Tj ET Q q 0 0 0 rg BT 199.58 545.25 Td (with ) Tj ET Q q 0 0 0 rg BT 219.92 545.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 257.47 545.25 Td (to ) Tj ET Q q 0 0 0 rg BT 267.82 545.25 Td (be ) Tj ET Q q 0 0 0 rg BT 279.82 545.25 Td (used ) Tj ET Q q 0 0 0 rg BT 300.71 545.25 Td (in ) Tj ET Q q 0 0 0 rg BT 311.05 545.25 Td (combination ) Tj ET Q q 0 0 0 rg BT 363.61 545.25 Td (with ) Tj ET Q q 0 0 0 rg BT 383.95 545.25 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 413.33 545.25 Td (immuno-oncology ) Tj ET Q q 0 0 0 rg BT 489.77 545.25 Td (portfolio. ) Tj ET Q q 0 0 0 rg BT 529.83 545.25 Td (In ) Tj ET Q q 0 0 0 rg BT 540.73 545.25 Td (addition, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.43 533.25 Td (transaction ) Tj ET Q q 0 0 0 rg BT 98.51 533.25 Td (included ) Tj ET Q q 0 0 0 rg BT 136.16 533.25 Td (Flexus's ) Tj ET Q q 0 0 0 rg BT 171.73 533.25 Td (IDO/TDO ) Tj ET Q q 0 0 0 rg BT 216.05 533.25 Td (discovery ) Tj ET Q q 0 0 0 rg BT 258.14 533.25 Td (program ) Tj ET Q q 0 0 0 rg BT 295.23 533.25 Td (which ) Tj ET Q q 0 0 0 rg BT 322.88 533.25 Td (included ) Tj ET Q q 0 0 0 rg BT 360.52 533.25 Td (its ) Tj ET Q q 0 0 0 rg BT 373.18 533.25 Td (IDO-selective, ) Tj ET Q q 0 0 0 rg BT 434.98 533.25 Td (IDO/TDO ) Tj ET Q q 0 0 0 rg BT 479.29 533.25 Td (dual ) Tj ET Q q 0 0 0 rg BT 499.72 533.25 Td (and ) Tj ET Q q 0 0 0 rg BT 517.14 533.25 Td (TDO-selective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (compounds.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 510.18 40.00 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 501.9169921875 m 75.9951171875 501.9169921875 l s q 0 0 0 rg BT 36.00 503.25 Td (Cardioxyl) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 76.00 510.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 76.00 503.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 78.77 503.25 Td ( ) Tj ET Q q 0 0 0 rg BT 81.15 503.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 104.65 503.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 141.45 503.25 Td (all ) Tj ET Q q 0 0 0 rg BT 153.83 503.25 Td (of ) Tj ET Q q 0 0 0 rg BT 164.54 503.25 Td (the ) Tj ET Q q 0 0 0 rg BT 179.13 503.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 228.17 503.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 255.54 503.25 Td (of ) Tj ET Q q 0 0 0 rg BT 266.25 503.25 Td (Cardioxyl ) Tj ET Q q 0 0 0 rg BT 308.62 503.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 349.89 503.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 373.39 503.25 Td (with ) Tj ET Q q 0 0 0 rg BT 393.54 503.25 Td (full ) Tj ET Q q 0 0 0 rg BT 409.81 503.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 434.96 503.25 Td (to ) Tj ET Q q 0 0 0 rg BT 445.12 503.25 Td (CXL-1427, ) Tj ET Q q 0 0 0 rg BT 493.33 503.25 Td (a ) Tj ET Q q 0 0 0 rg BT 500.15 503.25 Td (nitroxyl ) Tj ET Q q 0 0 0 rg BT 534.19 503.25 Td (prodrug ) Tj ET Q q 0 0 0 rg BT 568.23 503.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 491.25 Td (development ) Tj ET Q q 0 0 0 rg BT 90.15 491.25 Td (for ) Tj ET Q q 0 0 0 rg BT 104.31 491.25 Td (acute ) Tj ET Q q 0 0 0 rg BT 127.90 491.25 Td (decompensated ) Tj ET Q q 0 0 0 rg BT 192.04 491.25 Td (heart ) Tj ET Q q 0 0 0 rg BT 214.53 491.25 Td (failure.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 480.18 43.09 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 471.9169921875 m 79.09326171875 471.9169921875 l s q 0 0 0 rg BT 36.00 473.25 Td (Five ) Tj ET Q q 0 0 0 rg BT 55.21 473.25 Td (Prime) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 79.09 480.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 79.09 473.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 81.87 473.25 Td ( ) Tj ET Q q 0 0 0 rg BT 83.30 473.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 105.85 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 121.72 473.25 Td (Five ) Tj ET Q q 0 0 0 rg BT 140.92 473.25 Td (Prime ) Tj ET Q q 0 0 0 rg BT 166.24 473.25 Td (entered ) Tj ET Q q 0 0 0 rg BT 197.09 473.25 Td (into ) Tj ET Q q 0 0 0 rg BT 214.08 473.25 Td (an ) Tj ET Q q 0 0 0 rg BT 224.94 473.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 264.13 473.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 308.33 473.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 345.86 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 361.73 473.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 415.92 473.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 458.99 473.25 Td (to ) Tj ET Q q 0 0 0 rg BT 468.19 473.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 501.28 473.25 Td (and ) Tj ET Q q 0 0 0 rg BT 517.14 473.25 Td (commercialize ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.25 Td (Five ) Tj ET Q q 0 0 0 rg BT 57.65 461.25 Td (Prime’) Tj ET Q q 0 0 0 rg BT 84.32 461.25 Td (s ) Tj ET Q q 0 0 0 rg BT 92.09 461.25 Td (CSF1R ) Tj ET Q q 0 0 0 rg BT 125.42 461.25 Td (antibody ) Tj ET Q q 0 0 0 rg BT 164.29 461.25 Td (program, ) Tj ET Q q 0 0 0 rg BT 204.55 461.25 Td (including ) Tj ET Q q 0 0 0 rg BT 246.20 461.25 Td (cabiralizumab ) Tj ET Q q 0 0 0 rg BT 306.71 461.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 346.68 461.25 Td (in ) Tj ET Q q 0 0 0 rg BT 358.33 461.25 Td (development ) Tj ET Q q 0 0 0 rg BT 413.86 461.25 Td (for ) Tj ET Q q 0 0 0 rg BT 429.39 461.25 Td (IO ) Tj ET Q q 0 0 0 rg BT 443.82 461.25 Td (indications ) Tj ET Q q 0 0 0 rg BT 491.58 461.25 Td (and ) Tj ET Q q 0 0 0 rg BT 509.89 461.25 Td (PVNS. ) Tj ET Q q 0 0 0 rg BT 541.83 461.25 Td ( BMS ) Tj ET Q q 0 0 0 rg BT 569.33 461.25 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 83.12 449.25 Td (for ) Tj ET Q q 0 0 0 rg BT 96.35 449.25 Td (the ) Tj ET Q q 0 0 0 rg BT 110.15 449.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 165.87 449.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 225.75 449.25 Td (and ) Tj ET Q q 0 0 0 rg BT 241.77 449.25 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 317.75 449.25 Td (of ) Tj ET Q q 0 0 0 rg BT 327.65 449.25 Td (cabiralizumab, ) Tj ET Q q 0 0 0 rg BT 388.36 449.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 418.26 449.25 Td (to ) Tj ET Q q 0 0 0 rg BT 427.61 449.25 Td (Five ) Tj ET Q q 0 0 0 rg BT 446.96 449.25 Td (Prime’) Tj ET Q q 0 0 0 rg BT 473.63 449.25 Td (s ) Tj ET Q q 0 0 0 rg BT 479.10 449.25 Td (option ) Tj ET Q q 0 0 0 rg BT 506.23 449.25 Td (to ) Tj ET Q q 0 0 0 rg BT 515.58 449.25 Td (conduct ) Tj ET Q q 0 0 0 rg BT 548.81 449.25 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 66.28 437.25 Td (at ) Tj ET Q q 0 0 0 rg BT 76.00 437.25 Td (its ) Tj ET Q q 0 0 0 rg BT 87.94 437.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 106.55 437.25 Td (to ) Tj ET Q q 0 0 0 rg BT 116.83 437.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 150.99 437.25 Td (cabiralizumab ) Tj ET Q q 0 0 0 rg BT 210.12 437.25 Td (in ) Tj ET Q q 0 0 0 rg BT 220.40 437.25 Td (PVNS ) Tj ET Q q 0 0 0 rg BT 248.47 437.25 Td (and ) Tj ET Q q 0 0 0 rg BT 265.40 437.25 Td (in ) Tj ET Q q 0 0 0 rg BT 275.68 437.25 Td (combination ) Tj ET Q q 0 0 0 rg BT 328.17 437.25 Td (with ) Tj ET Q q 0 0 0 rg BT 348.45 437.25 Td (its ) Tj ET Q q 0 0 0 rg BT 360.40 437.25 Td (own ) Tj ET Q q 0 0 0 rg BT 380.12 437.25 Td (internal ) Tj ET Q q 0 0 0 rg BT 413.16 437.25 Td (oncology ) Tj ET Q q 0 0 0 rg BT 452.88 437.25 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 487.59 437.25 Td (assets.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 426.18 42.22 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 417.9169921875 m 78.216796875 417.9169921875 l s q 0 0 0 rg BT 36.00 419.25 Td (Promedior) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 78.22 426.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 78.22 419.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 81.00 419.25 Td ( ) Tj ET Q q 0 0 0 rg BT 82.46 419.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 105.05 419.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 140.93 419.25 Td (a ) Tj ET Q q 0 0 0 rg BT 146.84 419.25 Td (warrant ) Tj ET Q q 0 0 0 rg BT 178.84 419.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 219.19 419.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 241.77 419.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 281.00 419.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 305.24 419.25 Td (to ) Tj ET Q q 0 0 0 rg BT 314.49 419.25 Td (acquire ) Tj ET Q q 0 0 0 rg BT 345.37 419.25 Td (Promedior) Tj ET Q q 0 0 0 rg BT 387.19 419.25 Td (, ) Tj ET Q q 0 0 0 rg BT 391.15 419.25 Td (whose ) Tj ET Q q 0 0 0 rg BT 418.17 419.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 436.29 419.25 Td (asset, ) Tj ET Q q 0 0 0 rg BT 459.69 419.25 Td (PRM-151, ) Tj ET Q q 0 0 0 rg BT 503.11 419.25 Td (is ) Tj ET Q q 0 0 0 rg BT 511.24 419.25 Td (being ) Tj ET Q q 0 0 0 rg BT 534.92 419.25 Td (developed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 407.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.28 407.25 Td (the ) Tj ET Q q 0 0 0 rg BT 65.12 407.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 105.50 407.25 Td (of ) Tj ET Q q 0 0 0 rg BT 116.45 407.25 Td (IPF ) Tj ET Q q 0 0 0 rg BT 133.52 407.25 Td (and ) Tj ET Q q 0 0 0 rg BT 150.58 407.25 Td (MF) Tj ET Q q 0 0 0 rg BT 164.24 407.25 Td (. ) Tj ET Q q 0 0 0 rg BT 169.17 407.25 Td (The ) Tj ET Q q 0 0 0 rg BT 187.34 407.25 Td (warrant ) Tj ET Q q 0 0 0 rg BT 220.49 407.25 Td (is ) Tj ET Q q 0 0 0 rg BT 229.79 407.25 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 277.38 407.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 300.00 407.25 Td (being ) Tj ET Q q 0 0 0 rg BT 324.84 407.25 Td (provided ) Tj ET Q q 0 0 0 rg BT 363.00 407.25 Td (data ) Tj ET Q q 0 0 0 rg BT 382.28 407.25 Td (following ) Tj ET Q q 0 0 0 rg BT 423.79 407.25 Td (completion ) Tj ET Q q 0 0 0 rg BT 471.40 407.25 Td (of ) Tj ET Q q 0 0 0 rg BT 482.35 407.25 Td (either ) Tj ET Q q 0 0 0 rg BT 507.74 407.25 Td (of ) Tj ET Q q 0 0 0 rg BT 518.69 407.25 Td (the ) Tj ET Q q 0 0 0 rg BT 533.52 407.25 Td (IPF ) Tj ET Q q 0 0 0 rg BT 550.60 407.25 Td (or ) Tj ET Q q 0 0 0 rg BT 561.55 407.25 Td (MF ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 395.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 61.83 395.25 Td (II ) Tj ET Q q 0 0 0 rg BT 70.99 395.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 102.92 395.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 133.20 395.25 Td (being ) Tj ET Q q 0 0 0 rg BT 157.91 395.25 Td (directed ) Tj ET Q q 0 0 0 rg BT 192.62 395.25 Td (by ) Tj ET Q q 0 0 0 rg BT 205.12 395.25 Td (Promedior) Tj ET Q q 0 0 0 rg BT 246.78 395.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 384.18 65.95 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 375.9169921875 m 101.95361328125 375.9169921875 l s q 0 0 0 rg BT 36.00 377.25 Td (Bavarian ) Tj ET Q q 0 0 0 rg BT 74.19 377.25 Td (Nordic) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 101.95 384.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 101.95 377.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 104.73 377.25 Td ( ) Tj ET Q q 0 0 0 rg BT 106.82 377.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 130.04 377.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 166.55 377.25 Td (an ) Tj ET Q q 0 0 0 rg BT 178.08 377.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 217.94 377.25 Td (option ) Tj ET Q q 0 0 0 rg BT 245.59 377.25 Td (to ) Tj ET Q q 0 0 0 rg BT 255.46 377.25 Td (globally ) Tj ET Q q 0 0 0 rg BT 290.32 377.25 Td (license ) Tj ET Q q 0 0 0 rg BT 320.17 377.25 Td (and ) Tj ET Q q 0 0 0 rg BT 336.70 377.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 397.65 377.25 Td (Pr) Tj ET Q q 0 0 0 rg BT 407.28 377.25 Td (ostvac) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.82 377.25 Td (*, ) Tj ET Q q 0 0 0 rg BT 442.42 377.25 Td (Bavarian ) Tj ET Q q 0 0 0 rg BT 480.60 377.25 Td (Nordic’) Tj ET Q q 0 0 0 rg BT 511.15 377.25 Td (s ) Tj ET Q q 0 0 0 rg BT 517.13 377.25 Td (investigational ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 62.77 365.25 Td (III ) Tj ET Q q 0 0 0 rg BT 76.20 365.25 Td (prostate-specific ) Tj ET Q q 0 0 0 rg BT 145.72 365.25 Td (antigen-tar) Tj ET Q q 0 0 0 rg BT 188.85 365.25 Td (geting ) Tj ET Q q 0 0 0 rg BT 217.28 365.25 Td (cancer ) Tj ET Q q 0 0 0 rg BT 246.80 365.25 Td (immunotherapy ) Tj ET Q q 0 0 0 rg BT 313.56 365.25 Td (in ) Tj ET Q q 0 0 0 rg BT 324.78 365.25 Td (development ) Tj ET Q q 0 0 0 rg BT 379.87 365.25 Td (for ) Tj ET Q q 0 0 0 rg BT 394.97 365.25 Td (the ) Tj ET Q q 0 0 0 rg BT 410.62 365.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 451.82 365.25 Td (of ) Tj ET Q q 0 0 0 rg BT 463.59 365.25 Td (asymptomatic ) Tj ET Q q 0 0 0 rg BT 523.13 365.25 Td (or ) Tj ET Q q 0 0 0 rg BT 534.90 365.25 Td (minimally ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (symptomatic ) Tj ET Q q 0 0 0 rg BT 90.69 353.25 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 134.25 353.25 Td (castration-resistant ) Tj ET Q q 0 0 0 rg BT 212.81 353.25 Td (prostate ) Tj ET Q q 0 0 0 rg BT 247.49 353.25 Td (cancer) Tj ET Q q 0 0 0 rg BT 273.02 353.25 Td (. ) Tj ET Q q 0 0 0 rg BT 278.55 353.25 Td (In ) Tj ET Q q 0 0 0 rg BT 289.91 353.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 315.43 353.25 Td (an ) Tj ET Q q 0 0 0 rg BT 327.90 353.25 Td (independent ) Tj ET Q q 0 0 0 rg BT 379.80 353.25 Td (Data ) Tj ET Q q 0 0 0 rg BT 401.70 353.25 Td (Monitoring ) Tj ET Q q 0 0 0 rg BT 450.29 353.25 Td (Committee ) Tj ET Q q 0 0 0 rg BT 497.75 353.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 545.76 353.25 Td (that ) Tj ET Q q 0 0 0 rg BT 563.78 353.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (continuation ) Tj ET Q q 0 0 0 rg BT 88.49 341.25 Td (of ) Tj ET Q q 0 0 0 rg BT 99.32 341.25 Td (the ) Tj ET Q q 0 0 0 rg BT 114.04 341.25 Td (Phase ) Tj ET Q q 0 0 0 rg BT 139.87 341.25 Td (III ) Tj ET Q q 0 0 0 rg BT 152.36 341.25 Td (PROSPECT) Tj ET Q q 0 0 0 rg BT 201.64 341.25 Td ( ) Tj ET Q q 0 0 0 rg BT 204.14 341.25 Td (study ) Tj ET Q q 0 0 0 rg BT 228.31 341.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 239.14 341.25 Td (Pr) Tj ET Q q 0 0 0 rg BT 248.77 341.25 Td (ostvac) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 274.32 341.25 Td (* ) Tj ET Q q 0 0 0 rg BT 281.82 341.25 Td (in ) Tj ET Q q 0 0 0 rg BT 292.09 341.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 325.70 341.25 Td (with ) Tj ET Q q 0 0 0 rg BT 345.98 341.25 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 389.01 341.25 Td (castration-resistant ) Tj ET Q q 0 0 0 rg BT 467.04 341.25 Td (prostate ) Tj ET Q q 0 0 0 rg BT 501.20 341.25 Td (cancer ) Tj ET Q q 0 0 0 rg BT 529.78 341.25 Td (is ) Tj ET Q q 0 0 0 rg BT 538.95 341.25 Td (futile.) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 36.00 330.18 32.77 -9.09 re f /GS0 gs 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 321.9169921875 m 68.7685546875 321.9169921875 l s q 0 0 0 rg BT 36.00 323.25 Td (uniQure) Tj ET Q BT /F1 10.00 Tf ET 1 1 1 rg /GS0 gs 68.77 330.18 2.78 -9.09 re f /GS0 gs q 0 0 0 rg BT 68.77 323.25 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 71.55 323.25 Td ( ) Tj ET Q q 0 0 0 rg BT 74.40 323.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 98.37 323.25 Td (entered ) Tj ET Q q 0 0 0 rg BT 130.64 323.25 Td (into ) Tj ET Q q 0 0 0 rg BT 149.04 323.25 Td (a ) Tj ET Q q 0 0 0 rg BT 156.33 323.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 211.94 323.25 Td (and ) Tj ET Q q 0 0 0 rg BT 229.22 323.25 Td (license ) Tj ET Q q 0 0 0 rg BT 259.83 323.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 304.32 323.25 Td (with ) Tj ET Q q 0 0 0 rg BT 324.95 323.25 Td (uniQure ) Tj ET Q q 0 0 0 rg BT 360.57 323.25 Td (granting ) Tj ET Q q 0 0 0 rg BT 396.74 323.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 420.71 323.25 Td (an ) Tj ET Q q 0 0 0 rg BT 433.00 323.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 473.61 323.25 Td (license ) Tj ET Q q 0 0 0 rg BT 504.22 323.25 Td (to ) Tj ET Q q 0 0 0 rg BT 514.85 323.25 Td (uniQure’) Tj ET Q q 0 0 0 rg BT 550.40 323.25 Td (s ) Tj ET Q q 0 0 0 rg BT 557.13 323.25 Td (gene ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 311.25 Td (therapy ) Tj ET Q q 0 0 0 rg BT 68.78 311.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 116.01 311.25 Td (platform ) Tj ET Q q 0 0 0 rg BT 153.24 311.25 Td (for ) Tj ET Q q 0 0 0 rg BT 167.69 311.25 Td (up ) Tj ET Q q 0 0 0 rg BT 180.49 311.25 Td (to ) Tj ET Q q 0 0 0 rg BT 191.06 311.25 Td (10 ) Tj ET Q q 0 0 0 rg BT 203.86 311.25 Td (specific ) Tj ET Q q 0 0 0 rg BT 237.75 311.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 293.30 311.25 Td (tar) Tj ET Q q 0 0 0 rg BT 303.67 311.25 Td (gets. ) Tj ET Q q 0 0 0 rg BT 324.87 311.25 Td (The ) Tj ET Q q 0 0 0 rg BT 343.21 311.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 398.77 311.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 434.89 311.25 Td (uniQure’) Tj ET Q q 0 0 0 rg BT 470.43 311.25 Td (s ) Tj ET Q q 0 0 0 rg BT 477.12 311.25 Td (proprietary ) Tj ET Q q 0 0 0 rg BT 524.34 311.25 Td (gene ) Tj ET Q q 0 0 0 rg BT 546.01 311.25 Td (therapy ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 299.25 Td (program ) Tj ET Q q 0 0 0 rg BT 73.01 299.25 Td (for ) Tj ET Q q 0 0 0 rg BT 87.80 299.25 Td (congestive ) Tj ET Q q 0 0 0 rg BT 133.70 299.25 Td (heart ) Tj ET Q q 0 0 0 rg BT 156.82 299.25 Td (failure ) Tj ET Q q 0 0 0 rg BT 186.05 299.25 Td (that ) Tj ET Q q 0 0 0 rg BT 204.18 299.25 Td (is ) Tj ET Q q 0 0 0 rg BT 213.98 299.25 Td (intended ) Tj ET Q q 0 0 0 rg BT 251.55 299.25 Td (to ) Tj ET Q q 0 0 0 rg BT 262.46 299.25 Td (restore ) Tj ET Q q 0 0 0 rg BT 292.80 299.25 Td (the ) Tj ET Q q 0 0 0 rg BT 308.15 299.25 Td (heart’) Tj ET Q q 0 0 0 rg BT 330.92 299.25 Td (s ) Tj ET Q q 0 0 0 rg BT 337.94 299.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 366.63 299.25 Td (to ) Tj ET Q q 0 0 0 rg BT 377.54 299.25 Td (synthesize ) Tj ET Q q 0 0 0 rg BT 422.33 299.25 Td (S100A1, ) Tj ET Q q 0 0 0 rg BT 460.75 299.25 Td (a ) Tj ET Q q 0 0 0 rg BT 468.32 299.25 Td (calcium ) Tj ET Q q 0 0 0 rg BT 503.10 299.25 Td (sensor ) Tj ET Q q 0 0 0 rg BT 531.79 299.25 Td (and ) Tj ET Q q 0 0 0 rg BT 549.36 299.25 Td (master ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 287.25 Td (regulator ) Tj ET Q q 0 0 0 rg BT 74.59 287.25 Td (of ) Tj ET Q q 0 0 0 rg BT 85.42 287.25 Td (heart ) Tj ET Q q 0 0 0 rg BT 107.91 287.25 Td (function, ) Tj ET Q q 0 0 0 rg BT 146.23 287.25 Td (and ) Tj ET Q q 0 0 0 rg BT 163.17 287.25 Td (thereby ) Tj ET Q q 0 0 0 rg BT 195.66 287.25 Td (improve ) Tj ET Q q 0 0 0 rg BT 231.48 287.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 263.41 287.25 Td (outcomes ) Tj ET Q q 0 0 0 rg BT 304.24 287.25 Td (for ) Tj ET Q q 0 0 0 rg BT 318.40 287.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 352.00 287.25 Td (with ) Tj ET Q q 0 0 0 rg BT 372.28 287.25 Td (reduced ) Tj ET Q q 0 0 0 rg BT 406.42 287.25 Td (ejection ) Tj ET Q q 0 0 0 rg BT 440.58 287.25 Td (fraction. ) Tj ET Q endstream endobj 67 0 obj <> endobj 68 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (33) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (RESUL) Tj ET Q q 0 0 0 rg BT 68.43 749.25 Td (TS OF) Tj ET Q q 0 0 0 rg BT 96.67 749.25 Td ( OPERA) Tj ET Q q 0 0 0 rg BT 133.43 749.25 Td (TIONS) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (Regional Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 708.25 Td (The composition of the changes in revenues was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 649.75 187.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 223.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 227.50 649.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 272.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 276.50 649.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 649.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 374.50 649.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 419.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 423.50 649.75 50.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 473.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 477.50 649.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 649.75 50.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 623.75 187.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 223.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 227.50 623.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 272.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 276.50 623.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 623.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 374.50 623.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 419.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 423.50 623.75 50.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 473.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 477.50 623.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 623.75 50.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 597.75 187.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 223.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 227.50 597.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 272.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 276.50 597.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 597.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 374.50 597.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 419.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 423.50 597.75 50.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 473.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 477.50 597.75 45.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 597.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 597.75 50.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 685.75 m 272.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 272.5 685.75 m 276.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 685.75 m 321.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 321.5 685.75 m 325.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 685.75 m 370.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 374.5 685.75 m 419.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 419.5 685.75 m 423.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 423.5 685.75 m 473.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 477.5 685.75 m 522.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 522.5 685.75 m 526.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 685.75 m 576.5 685.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 672.75 m 272.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 272.5 672.75 m 276.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 672.75 m 321.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 321.5 672.75 m 325.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 672.75 m 370.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 374.5 672.75 m 419.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 419.5 672.75 m 423.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 423.5 672.75 m 473.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 477.5 672.75 m 522.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 522.5 672.75 m 526.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 672.75 m 576.5 672.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 649.75 m 272.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 649.75 m 321.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 649.75 m 370.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 374.5 649.75 m 419.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 423.5 649.75 m 473.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 477.5 649.75 m 522.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 649.75 m 576.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 649.75 m 272.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 649.75 m 321.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 649.75 m 370.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 477.5 649.75 m 522.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 649.75 m 576.5 649.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 597.75 m 272.5 597.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 597.75 m 321.5 597.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 597.75 m 370.5 597.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 585.75 m 272.5 585.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 227.5 583.75 m 272.5 583.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 585.75 m 321.5 585.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 276.5 583.75 m 321.5 583.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 585.75 m 370.5 585.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 583.75 m 370.5 583.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 689.70 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 254.20 689.83 Td (Y) Tj ET Q q 0 0 0 rg BT 259.53 689.83 Td (ear) Tj ET Q q 0 0 0 rg BT 270.12 689.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 330.85 689.83 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 400.90 689.83 Td (2017 vs. 2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 503.90 689.83 Td (2016 vs. 2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 677.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 272.50 676.98 Td (T) Tj ET Q q 0 0 0 rg BT 277.47 676.98 Td (otal Revenues) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 385.60 676.98 Td (Analysis of % Change) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 488.60 676.98 Td (Analysis of % Change) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 664.70 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 230.00 664.70 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 279.00 664.70 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 328.00 664.70 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.75 664.83 Td (T) Tj ET Q q 0 0 0 rg BT 392.72 664.83 Td (otal) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 434.70 664.83 Td (For) Tj ET Q q 0 0 0 rg BT 447.07 664.83 Td (eign) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 490.75 664.83 Td (T) Tj ET Q q 0 0 0 rg BT 495.72 664.83 Td (otal) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 537.70 664.83 Td (For) Tj ET Q q 0 0 0 rg BT 550.07 664.83 Td (eign) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 653.70 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 241.50 653.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 290.50 653.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 339.50 653.83 Td (2015) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 383.35 653.83 Td (Change) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 426.15 653.83 Td ( Exchange) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 463.49 657.46 Td (\(b\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 486.35 653.83 Td (Change) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 529.15 653.83 Td ( Exchange) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 566.49 657.46 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 640.32 Td (United States) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 230.00 640.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 241.10 640.32 Td (1) Tj ET Q q 0 0 0 rg BT 246.10 640.32 Td (1,358) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 279.00 640.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.10 640.32 Td (10,720) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.00 640.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.15 640.32 Td (8,188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.30 640.32 Td (6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 640.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 640.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.30 640.32 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.65 640.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.25 640.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 627.32 Td (Europe) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 246.15 627.32 Td (4,988) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 627.32 Td (4,215) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.15 627.32 Td (3,491) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.30 627.32 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 627.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.65 627.32 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.65 627.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.30 627.32 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.65 627.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.95 627.37 Td (\(2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 627.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 614.32 Td (Rest of the ) Tj ET Q q 0 0 0 rg BT 84.73 614.32 Td (W) Tj ET Q q 0 0 0 rg BT 93.68 614.32 Td (orld) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 246.15 614.32 Td (3,877) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 614.32 Td (3,964) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.15 614.32 Td (4,142) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.95 614.32 Td (\(2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.30 614.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 614.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.95 614.32 Td (\(4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.30 614.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.95 614.37 Td (\(4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 614.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 601.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 61.77 605.85 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 253.65 601.32 Td (553) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.65 601.32 Td (528) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 351.65 601.32 Td (739) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.30 601.32 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 601.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.30 601.32 Td (N/A) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.95 601.32 Td (\(29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.30 601.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.30 601.32 Td (N/A) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 588.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 588.32 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 230.00 588.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 241.10 588.32 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 279.00 588.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.10 588.32 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.00 588.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.10 588.32 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.30 588.32 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 588.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 588.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.30 588.32 Td (17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.65 588.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.95 588.37 Td (\(2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 588.32 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 572.65 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 58.50 572.65 Td (Other revenues include royalties and alliance-related revenues for products not sold by our regional commercial or) Tj ET Q q 0 0 0 rg BT 425.11 572.65 Td (ganizations.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 563.05 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 58.50 563.05 Td (Foreign exchange impacts were derived by applying the prior period average currency rates to the current period sales.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 541.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 56.52 541.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 94.80 541.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 135.29 541.45 Td (in ) Tj ET Q q 0 0 0 rg BT 145.81 541.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 168.55 541.45 Td (due ) Tj ET Q q 0 0 0 rg BT 185.73 541.45 Td (to ) Tj ET Q q 0 0 0 rg BT 196.24 541.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 224.53 541.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 258.92 541.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 273.32 541.45 Td (Eliquis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.40 541.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 321.58 541.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 351.01 541.45 Td ( ) Tj ET Q q 0 0 0 rg BT 353.75 541.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 389.81 541.45 Td (of) Tj ET Q q 0 0 0 rg BT 397.96 541.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 415.14 541.45 Td (by ) Tj ET Q q 0 0 0 rg BT 427.88 541.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 453.39 541.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 487.78 541.45 Td (for ) Tj ET Q q 0 0 0 rg BT 502.18 541.45 Td (established ) Tj ET Q q 0 0 0 rg BT 549.35 541.45 Td (brands ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 529.45 Td (due ) Tj ET Q q 0 0 0 rg BT 52.96 529.45 Td (to ) Tj ET Q q 0 0 0 rg BT 63.27 529.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 103.55 529.45 Td (competition, ) Tj ET Q q 0 0 0 rg BT 156.34 529.45 Td (primarily ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 196.08 529.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 232.19 529.45 Td ( ) Tj ET Q q 0 0 0 rg BT 234.71 529.45 Td (and ) Tj ET Q q 0 0 0 rg BT 251.68 529.45 Td (HIV) Tj ET Q q 0 0 0 rg BT 269.27 529.45 Td ( ) Tj ET Q q 0 0 0 rg BT 271.80 529.45 Td (brands. ) Tj ET Q q 0 0 0 rg BT 303.30 529.45 Td (The ) Tj ET Q q 0 0 0 rg BT 321.37 529.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 346.67 529.45 Td (growth ) Tj ET Q q 0 0 0 rg BT 377.52 529.45 Td (rate ) Tj ET Q q 0 0 0 rg BT 395.04 529.45 Td (in ) Tj ET Q q 0 0 0 rg BT 405.34 529.45 Td (the ) Tj ET Q q 0 0 0 rg BT 420.08 529.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 440.39 529.45 Td (was ) Tj ET Q q 0 0 0 rg BT 458.47 529.45 Td (due ) Tj ET Q q 0 0 0 rg BT 475.43 529.45 Td (to ) Tj ET Q q 0 0 0 rg BT 485.74 529.45 Td (additional ) Tj ET Q q 0 0 0 rg BT 528.25 529.45 Td (competition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 517.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 49.77 517.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 79.21 517.45 Td ( ) Tj ET Q q 0 0 0 rg BT 81.32 517.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 97.87 517.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 133.97 517.45 Td (. ) Tj ET Q q 0 0 0 rg BT 138.12 517.45 Td (A) Tj ET Q q 0 0 0 rg BT 144.60 517.45 Td (verage ) Tj ET Q q 0 0 0 rg BT 173.35 517.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 193.24 517.45 Td (net ) Tj ET Q q 0 0 0 rg BT 207.57 517.45 Td (selling ) Tj ET Q q 0 0 0 rg BT 236.35 517.45 Td (prices ) Tj ET Q q 0 0 0 rg BT 262.33 517.45 Td (were ) Tj ET Q q 0 0 0 rg BT 283.87 517.45 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.74 517.45 Td (2%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.07 517.45 Td ( ) Tj ET Q q 0 0 0 rg BT 359.18 517.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 386.83 517.45 Td (after ) Tj ET Q q 0 0 0 rg BT 407.26 517.45 Td (char) Tj ET Q q 0 0 0 rg BT 424.28 517.45 Td (ge-backs, ) Tj ET Q q 0 0 0 rg BT 464.43 517.45 Td (rebates ) Tj ET Q q 0 0 0 rg BT 494.86 517.45 Td (and ) Tj ET Q q 0 0 0 rg BT 511.40 517.45 Td (discounts. ) Tj ET Q q 0 0 0 rg BT 553.79 517.45 Td (Refer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 505.45 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 505.45 Td ("—Product ) Tj ET Q q 0 0 0 rg BT 93.97 505.45 Td (Revenues ) Tj ET Q q 0 0 0 rg BT 135.35 505.45 Td (Commentary" ) Tj ET Q q 0 0 0 rg BT 194.14 505.45 Td (for ) Tj ET Q q 0 0 0 rg BT 208.30 505.45 Td (additional ) Tj ET Q q 0 0 0 rg BT 250.79 505.45 Td (information.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 481.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 56.50 481.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 94.75 481.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 135.23 481.45 Td (in ) Tj ET Q q 0 0 0 rg BT 145.72 481.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 168.44 481.45 Td (due ) Tj ET Q q 0 0 0 rg BT 185.59 481.45 Td (to ) Tj ET Q q 0 0 0 rg BT 196.09 481.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 224.35 481.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 258.73 481.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 273.10 481.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.54 481.45 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 307.76 481.45 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.10 481.45 Td ( ) Tj ET Q q 0 0 0 rg BT 338.81 481.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 355.97 481.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.08 481.45 Td (, ) Tj ET Q q 0 0 0 rg BT 397.29 481.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 433.33 481.45 Td (of) Tj ET Q q 0 0 0 rg BT 441.48 481.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 458.64 481.45 Td (by ) Tj ET Q q 0 0 0 rg BT 471.35 481.45 Td (the ) Tj ET Q q 0 0 0 rg BT 486.29 481.45 Td (full ) Tj ET Q q 0 0 0 rg BT 502.89 481.45 Td (year ) Tj ET Q q 0 0 0 rg BT 522.82 481.45 Td (impact ) Tj ET Q q 0 0 0 rg BT 552.75 481.45 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 481.45 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 469.45 Td (expiration/transfer ) Tj ET Q q 0 0 0 rg BT 112.36 469.45 Td (of ) Tj ET Q q 0 0 0 rg BT 123.20 469.45 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 200.11 469.45 Td (rights ) Tj ET Q q 0 0 0 rg BT 225.39 469.45 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 235.68 469.45 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.34 469.45 Td ( ) Tj ET Q q 0 0 0 rg BT 269.84 469.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 286.79 469.45 Td (Erbitux*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.78 469.45 Td (. ) Tj ET Q q 0 0 0 rg BT 326.23 469.45 Td (A) Tj ET Q q 0 0 0 rg BT 332.71 469.45 Td (verage ) Tj ET Q q 0 0 0 rg BT 361.86 469.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 382.15 469.45 Td (net ) Tj ET Q q 0 0 0 rg BT 396.87 469.45 Td (selling ) Tj ET Q q 0 0 0 rg BT 426.04 469.45 Td (prices ) Tj ET Q q 0 0 0 rg BT 452.42 469.45 Td (were ) Tj ET Q q 0 0 0 rg BT 474.36 469.45 Td (approximately ) Tj ET Q q 0 0 0 rg BT 534.62 469.45 Td (5% ) Tj ET Q q 0 0 0 rg BT 550.46 469.45 Td (higher ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 457.45 Td (after ) Tj ET Q q 0 0 0 rg BT 56.82 457.45 Td (char) Tj ET Q q 0 0 0 rg BT 73.84 457.45 Td (ge-backs, ) Tj ET Q q 0 0 0 rg BT 114.38 457.45 Td (rebates ) Tj ET Q q 0 0 0 rg BT 145.19 457.45 Td (and ) Tj ET Q q 0 0 0 rg BT 162.13 457.45 Td (discounts.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 433.45 Td (Europe ) Tj ET Q q 0 0 0 rg BT 67.56 433.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 105.79 433.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 146.23 433.45 Td (in ) Tj ET Q q 0 0 0 rg BT 156.70 433.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 179.39 433.45 Td (due ) Tj ET Q q 0 0 0 rg BT 196.51 433.45 Td (to ) Tj ET Q q 0 0 0 rg BT 206.98 433.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 235.21 433.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 269.56 433.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 283.91 433.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.34 433.45 Td ( ) Tj ET Q q 0 0 0 rg BT 316.03 433.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 333.16 433.45 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 361.49 433.45 Td ( ) Tj ET Q q 0 0 0 rg BT 364.18 433.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 400.19 433.45 Td (of) Tj ET Q q 0 0 0 rg BT 408.34 433.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 425.47 433.45 Td (by ) Tj ET Q q 0 0 0 rg BT 438.15 433.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 463.61 433.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 497.95 433.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 512.30 433.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 548.41 433.45 Td ( ) Tj ET Q q 0 0 0 rg BT 551.10 433.45 Td (due ) Tj ET Q q 0 0 0 rg BT 568.22 433.45 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 421.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 75.78 421.45 Td (competition. ) Tj ET Q q 0 0 0 rg BT 128.07 421.45 Td (Europe ) Tj ET Q q 0 0 0 rg BT 158.96 421.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 196.52 421.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 236.30 421.45 Td (in ) Tj ET Q q 0 0 0 rg BT 246.10 421.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 268.12 421.45 Td (due ) Tj ET Q q 0 0 0 rg BT 284.58 421.45 Td (to ) Tj ET Q q 0 0 0 rg BT 294.38 421.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 321.95 421.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 355.62 421.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 369.31 421.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.74 421.45 Td ( ) Tj ET Q q 0 0 0 rg BT 400.77 421.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 417.23 421.45 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.56 421.45 Td ( ) Tj ET Q q 0 0 0 rg BT 447.58 421.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 482.92 421.45 Td (of) Tj ET Q q 0 0 0 rg BT 491.07 421.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 507.53 421.45 Td (by ) Tj ET Q q 0 0 0 rg BT 519.55 421.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 544.34 421.45 Td (demand ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 409.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 50.16 409.45 Td (Y) Tj ET Q q 0 0 0 rg BT 54.80 409.45 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 77.01 409.45 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 79.51 409.45 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 385.45 Td (Rest ) Tj ET Q q 0 0 0 rg BT 55.19 385.45 Td (of ) Tj ET Q q 0 0 0 rg BT 64.94 385.45 Td (the ) Tj ET Q q 0 0 0 rg BT 78.47 385.45 Td (W) Tj ET Q q 0 0 0 rg BT 87.11 385.45 Td (orld ) Tj ET Q q 0 0 0 rg BT 104.63 385.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 141.58 385.45 Td (decreased ) Tj ET Q q 0 0 0 rg BT 182.41 385.45 Td (in ) Tj ET Q q 0 0 0 rg BT 191.60 385.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 213.02 385.45 Td (due ) Tj ET Q q 0 0 0 rg BT 228.87 385.45 Td (to ) Tj ET Q q 0 0 0 rg BT 238.07 385.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 262.25 385.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 295.32 385.45 Td (for ) Tj ET Q q 0 0 0 rg BT 308.39 385.45 Td (established ) Tj ET Q q 0 0 0 rg BT 354.24 385.45 Td (brands, ) Tj ET Q q 0 0 0 rg BT 384.82 385.45 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 424.01 385.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.12 385.45 Td (, ) Tj ET Q q 0 0 0 rg BT 464.03 385.45 Td (due ) Tj ET Q q 0 0 0 rg BT 479.88 385.45 Td (to ) Tj ET Q q 0 0 0 rg BT 489.08 385.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 528.25 385.45 Td (competition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 373.45 Td (and ) Tj ET Q q 0 0 0 rg BT 53.90 373.45 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 109.57 373.45 Td (of ) Tj ET Q q 0 0 0 rg BT 121.36 373.45 Td (a ) Tj ET Q q 0 0 0 rg BT 129.25 373.45 Td (mature ) Tj ET Q q 0 0 0 rg BT 160.48 373.45 Td (brand ) Tj ET Q q 0 0 0 rg BT 186.70 373.45 Td (product, ) Tj ET Q q 0 0 0 rg BT 223.21 373.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 259.99 373.45 Td (of) Tj ET Q q 0 0 0 rg BT 268.14 373.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 286.03 373.45 Td (by ) Tj ET Q q 0 0 0 rg BT 299.49 373.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 328.50 373.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 363.61 373.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 378.73 373.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.17 373.45 Td ( ) Tj ET Q q 0 0 0 rg BT 411.63 373.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 429.52 373.45 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.86 373.45 Td (. ) Tj ET Q q 0 0 0 rg BT 463.82 373.45 Td (Rest ) Tj ET Q q 0 0 0 rg BT 485.05 373.45 Td (of ) Tj ET Q q 0 0 0 rg BT 496.84 373.45 Td (the ) Tj ET Q q 0 0 0 rg BT 512.27 373.45 Td (W) Tj ET Q q 0 0 0 rg BT 520.90 373.45 Td (orld ) Tj ET Q q 0 0 0 rg BT 540.47 373.45 Td (revenues ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 361.45 Td (decreased ) Tj ET Q q 0 0 0 rg BT 77.44 361.45 Td (in ) Tj ET Q q 0 0 0 rg BT 87.25 361.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 109.28 361.45 Td (due ) Tj ET Q q 0 0 0 rg BT 125.74 361.45 Td (to ) Tj ET Q q 0 0 0 rg BT 135.55 361.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 175.33 361.45 Td (competition ) Tj ET Q q 0 0 0 rg BT 225.13 361.45 Td (for ) Tj ET Q q 0 0 0 rg BT 238.81 361.45 Td (the ) Tj ET Q q 0 0 0 rg BT 253.06 361.45 Td (Hepatitis ) Tj ET Q q 0 0 0 rg BT 291.19 361.45 Td (C ) Tj ET Q q 0 0 0 rg BT 299.89 361.45 Td (Franchise ) Tj ET Q q 0 0 0 rg BT 340.79 361.45 Td (in ) Tj ET Q q 0 0 0 rg BT 350.60 361.45 Td (Japan ) Tj ET Q q 0 0 0 rg BT 375.40 361.45 Td (and ) Tj ET Q q 0 0 0 rg BT 391.86 361.45 Td (unfavorable ) Tj ET Q q 0 0 0 rg BT 441.64 361.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 472.55 361.45 Td (exchange ) Tj ET Q q 0 0 0 rg BT 512.33 361.45 Td (\(primarily ) Tj ET Q q 0 0 0 rg BT 554.90 361.45 Td (Latin ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.45 Td (America\) ) Tj ET Q q 0 0 0 rg BT 76.25 349.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 112.07 349.45 Td (of) Tj ET Q q 0 0 0 rg BT 120.22 349.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 137.16 349.45 Td (by ) Tj ET Q q 0 0 0 rg BT 149.66 349.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 177.71 349.45 Td (demand ) Tj ET Q q 0 0 0 rg BT 211.86 349.45 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 226.02 349.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 255.46 349.45 Td ( ) Tj ET Q q 0 0 0 rg BT 257.96 349.45 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 274.90 349.45 Td (Eliquis.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.45 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.21 325.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 99.19 325.45 Td (decreased ) Tj ET Q q 0 0 0 rg BT 141.05 325.45 Td (in ) Tj ET Q q 0 0 0 rg BT 151.27 325.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 173.72 325.45 Td (as ) Tj ET Q q 0 0 0 rg BT 184.49 325.45 Td (a ) Tj ET Q q 0 0 0 rg BT 191.37 325.45 Td (result ) Tj ET Q q 0 0 0 rg BT 216.03 325.45 Td (of ) Tj ET Q q 0 0 0 rg BT 226.81 325.45 Td (the ) Tj ET Q q 0 0 0 rg BT 241.47 325.45 Td (expiration ) Tj ET Q q 0 0 0 rg BT 284.45 325.45 Td (of ) Tj ET Q q 0 0 0 rg BT 295.23 325.45 Td (certain ) Tj ET Q q 0 0 0 rg BT 324.87 325.45 Td (supply ) Tj ET Q q 0 0 0 rg BT 353.99 325.45 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 412.79 325.45 Td (Refer ) Tj ET Q q 0 0 0 rg BT 437.45 325.45 Td (to ) Tj ET Q q 0 0 0 rg BT 447.67 325.45 Td ("Item ) Tj ET Q q 0 0 0 rg BT 472.52 325.45 Td (8. ) Tj ET Q q 0 0 0 rg BT 482.46 325.45 Td (Financial ) Tj ET Q q 0 0 0 rg BT 522.12 325.45 Td (Statements—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 313.45 Td (Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.94 313.45 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 62.94 313.45 Td (. ) Tj ET Q q 0 0 0 rg BT 67.39 313.45 Td (Alliances" ) Tj ET Q q 0 0 0 rg BT 111.73 313.45 Td (for ) Tj ET Q q 0 0 0 rg BT 125.89 313.45 Td (further ) Tj ET Q q 0 0 0 rg BT 155.60 313.45 Td (discussion ) Tj ET Q q 0 0 0 rg BT 199.77 313.45 Td (of ) Tj ET Q q 0 0 0 rg BT 210.60 313.45 Td (the ) Tj ET Q q 0 0 0 rg BT 225.32 313.45 Td (alliances.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 289.45 Td (No ) Tj ET Q q 0 0 0 rg BT 50.16 289.45 Td (single ) Tj ET Q q 0 0 0 rg BT 75.99 289.45 Td (country ) Tj ET Q q 0 0 0 rg BT 108.47 289.45 Td (outside ) Tj ET Q q 0 0 0 rg BT 139.30 289.45 Td (the ) Tj ET Q q 0 0 0 rg BT 153.45 289.45 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 173.17 289.45 Td (contributed ) Tj ET Q q 0 0 0 rg BT 220.65 289.45 Td (more ) Tj ET Q q 0 0 0 rg BT 243.14 289.45 Td (than ) Tj ET Q q 0 0 0 rg BT 262.29 289.45 Td (10% ) Tj ET Q q 0 0 0 rg BT 282.56 289.45 Td (of ) Tj ET Q q 0 0 0 rg BT 292.83 289.45 Td (total ) Tj ET Q q 0 0 0 rg BT 312.54 289.45 Td (revenues ) Tj ET Q q 0 0 0 rg BT 350.02 289.45 Td (except ) Tj ET Q q 0 0 0 rg BT 378.05 289.45 Td (for ) Tj ET Q q 0 0 0 rg BT 391.65 289.45 Td (Japan ) Tj ET Q q 0 0 0 rg BT 416.36 289.45 Td (which ) Tj ET Q q 0 0 0 rg BT 442.73 289.45 Td (contributed ) Tj ET Q q 0 0 0 rg BT 490.21 289.45 Td (10% ) Tj ET Q q 0 0 0 rg BT 510.48 289.45 Td (of ) Tj ET Q q 0 0 0 rg BT 520.75 289.45 Td (total ) Tj ET Q q 0 0 0 rg BT 540.46 289.45 Td (revenues ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 277.45 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 277.45 Td (2015.) 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/F1 10.00 Tf ET q 0 0 0 rg BT 332.65 592.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 386.80 592.37 Td (\(1,296) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 592.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.80 592.37 Td (\(1,397) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 592.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 592.37 Td (\(4,246) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 592.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 580.37 Td (Foreign currency translation and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 322.65 580.37 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.65 580.37 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 580.37 Td (\(31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 580.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 580.37 Td (\(31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 580.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 568.37 Td (Balance at December 31, 2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 568.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.65 568.37 Td (126) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.00 568.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.65 568.37 Td (520) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.00 568.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 568.37 Td (1,160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.00 568.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 568.37 Td (1,806) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 556.37 Td (Provision related to sale made in:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 544.37 Td (Current period) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.15 544.37 Td (2,087) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.15 544.37 Td (2,090) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 544.37 Td (2,135) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 544.37 Td (6,312) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 532.37 Td (Prior period) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 324.30 532.37 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.65 532.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.30 532.37 Td (\(4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 532.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 532.37 Td (\(64) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 532.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 532.37 Td (\(71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 532.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 520.37 Td (Payments and returns) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 306.80 520.37 Td (\(2,004) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.65 520.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 386.80 520.37 Td (\(1,810) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 520.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.80 520.37 Td (\(2,107) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 520.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 520.37 Td (\(5,921) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 520.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 508.37 Td (Foreign currency translation and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.65 508.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.65 508.37 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 508.37 Td (104) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 508.37 Td (107) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 496.37 Td (Balance at December 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 496.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.65 496.37 Td (209) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.00 496.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.65 496.37 Td (796) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.00 496.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 496.37 Td (1,228) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.00 496.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 496.37 Td (2,233) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 470.25 Td (The ) Tj ET Q q 0 0 0 rg BT 53.64 470.25 Td (reconciliation ) Tj ET Q q 0 0 0 rg BT 110.71 470.25 Td (of ) Tj ET Q q 0 0 0 rg BT 121.13 470.25 Td (gross ) Tj ET Q q 0 0 0 rg BT 144.33 470.25 Td (product ) Tj ET Q q 0 0 0 rg BT 176.97 470.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 198.50 470.25 Td (to ) Tj ET Q q 0 0 0 rg BT 208.37 470.25 Td (net ) Tj ET Q q 0 0 0 rg BT 222.68 470.25 Td (product ) Tj ET Q q 0 0 0 rg BT 255.31 470.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 276.84 470.25 Td (by ) Tj ET Q q 0 0 0 rg BT 288.94 470.25 Td (each ) Tj ET Q q 0 0 0 rg BT 309.34 470.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 353.65 470.25 Td (category ) Tj ET Q q 0 0 0 rg BT 390.16 470.25 Td (of ) Tj ET Q q 0 0 0 rg BT 400.58 470.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 423.23 470.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 473.09 470.25 Td (was ) Tj ET Q q 0 0 0 rg BT 490.73 470.25 Td (as ) Tj ET Q q 0 0 0 rg BT 501.15 470.25 Td (follows ) Tj ET Q q 0 0 0 rg BT 533.25 470.25 Td (\(excluding ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 458.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 69.59 458.25 Td (and ) Tj ET Q q 0 0 0 rg BT 86.53 458.25 Td (other ) Tj ET Q q 0 0 0 rg BT 109.57 458.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 147.61 458.25 Td (such ) Tj ET Q q 0 0 0 rg BT 168.44 458.25 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 179.27 458.25 Td (Abilify* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.43 458.25 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 230.37 458.25 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.71 458.25 Td (\):) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 423.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 423.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 423.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 423.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 423.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 423.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 423.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 423.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 423.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 423.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 423.75 52.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 399.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 399.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 399.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 399.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 399.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 399.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 399.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 399.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 399.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 399.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 399.75 52.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 375.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 375.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 375.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 375.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 375.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 375.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 375.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 375.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 375.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 375.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 375.75 52.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 351.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 351.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 351.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 351.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 351.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 351.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 351.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 351.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 351.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 351.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 351.75 52.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 327.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 327.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 327.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 327.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 327.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 327.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 327.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 327.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 327.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 327.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 327.75 52.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 303.75 277.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 313.50 303.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 317.50 303.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 303.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 303.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 303.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 417.50 303.75 46.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 303.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 303.75 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 303.75 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 524.50 303.75 52.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 435.75 m 363.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 435.75 m 367.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 435.75 m 413.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 435.75 m 417.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 435.75 m 463.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 435.75 m 520.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 435.75 m 524.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 435.75 m 576.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 423.75 m 363.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 423.75 m 413.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 423.75 m 463.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 423.75 m 520.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 435.75 m 576.5 435.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 423.75 m 576.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 423.75 m 520.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 423.75 m 576.5 423.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 363.75 m 363.5 363.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 363.75 m 413.5 363.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 363.75 m 463.5 363.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 363.75 m 520.5 363.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 363.75 m 576.5 363.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 351.75 m 363.5 351.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 340.75 m 363.5 340.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 317.5 338.75 m 363.5 338.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 351.75 m 413.5 351.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 340.75 m 413.5 340.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 338.75 m 413.5 338.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 351.75 m 463.5 351.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 340.75 m 463.5 340.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 417.5 338.75 m 463.5 338.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 351.75 m 520.5 351.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 340.75 m 520.5 340.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 467.5 338.75 m 520.5 338.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 351.75 m 576.5 351.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 340.75 m 576.5 340.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 524.5 338.75 m 576.5 338.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 439.70 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 345.70 439.83 Td (Y) Tj ET Q q 0 0 0 rg BT 351.03 439.83 Td (ear) Tj ET Q q 0 0 0 rg BT 361.62 439.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 422.35 439.83 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 503.35 439.83 Td (% Change) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 427.70 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 332.00 427.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 382.00 427.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 432.00 427.83 Td (2015) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 470.90 427.83 Td (2017 vs. 2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 527.40 427.83 Td (2016 vs. 2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 414.48 Td (Gr) Tj ET Q q 0 0 0 rg BT 51.13 414.48 Td (oss pr) Tj ET Q q 0 0 0 rg BT 76.23 414.48 Td (oduct sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.00 414.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.10 414.37 Td (25,499) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 414.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 377.10 414.37 Td (22,364) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.00 414.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.10 414.37 Td (17,166) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 414.37 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 414.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 414.37 Td (30) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 414.37 Td (%) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 402.48 Td (GTN ) Tj ET Q q 0 0 0 rg BT 62.89 402.48 Td (Adjustments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 390.37 Td (Char) Tj ET Q q 0 0 0 rg BT 58.35 390.37 Td (ge-backs and cash discounts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.80 390.37 Td (\(2,084) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 390.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.80 390.37 Td (\(1,582) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 390.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.80 390.37 Td (\(1,043) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 390.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 390.37 Td (32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 390.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 390.37 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 390.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 378.37 Td (Medicaid and Medicare rebates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.80 378.37 Td (\(2,086) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 378.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.80 378.37 Td (\(1,382) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 378.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.30 378.37 Td (\(859) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 378.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 378.37 Td (51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 378.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 378.37 Td (61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 378.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 366.37 Td (Other rebates, returns, discounts and adjustments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.80 366.37 Td (\(2,071) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 366.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.80 366.37 Td (\(1,698) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 366.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.80 366.37 Td (\(1,219) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 366.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 366.37 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 366.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 366.37 Td (39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 366.37 Td (%) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 354.48 Td (T) Tj ET Q q 0 0 0 rg BT 45.21 354.48 Td (otal GTN ) Tj ET Q q 0 0 0 rg BT 87.25 354.48 Td (Adjustments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.80 354.37 Td (\(6,241) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 354.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.80 354.37 Td (\(4,662) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 354.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.80 354.37 Td (\(3,121) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 354.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 354.37 Td (34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 354.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 354.37 Td (49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 354.37 Td (%) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 342.48 Td (Net pr) Tj ET Q q 0 0 0 rg BT 66.40 342.48 Td (oduct sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.00 342.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.10 342.37 Td (19,258) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 342.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 377.10 342.37 Td (17,702) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.00 342.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.10 342.37 Td (14,045) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 506.65 342.37 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 342.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 342.37 Td (26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 342.37 Td (%) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 318.48 Td (GTN adjustments per) Tj ET Q q 0 0 0 rg BT 132.15 318.48 Td (centage) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.65 318.37 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 318.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 318.37 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 318.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 318.37 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 318.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 506.65 318.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 318.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 318.37 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 318.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 306.37 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.65 306.37 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 306.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 306.37 Td (26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 306.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 306.37 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 306.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 506.65 306.37 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 306.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 306.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 306.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 294.37 Td (Non-U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.65 294.37 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 294.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 294.37 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.65 294.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 294.37 Td (1) Tj ET Q q 0 0 0 rg BT 449.65 294.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.65 294.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 294.37 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 294.37 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 294.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 274.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 58.97 274.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 109.16 274.25 Td (are ) Tj ET Q q 0 0 0 rg BT 123.78 274.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 163.41 274.25 Td (a ) Tj ET Q q 0 0 0 rg BT 170.27 274.25 Td (function ) Tj ET Q q 0 0 0 rg BT 206.01 274.25 Td (of ) Tj ET Q q 0 0 0 rg BT 216.76 274.25 Td (product ) Tj ET Q q 0 0 0 rg BT 249.72 274.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 271.58 274.25 Td (volume, ) Tj ET Q q 0 0 0 rg BT 306.49 274.25 Td (regional ) Tj ET Q q 0 0 0 rg BT 341.67 274.25 Td (and ) Tj ET Q q 0 0 0 rg BT 358.52 274.25 Td (payer ) Tj ET Q q 0 0 0 rg BT 383.15 274.25 Td (channel ) Tj ET Q q 0 0 0 rg BT 416.66 274.25 Td (mix, ) Tj ET Q q 0 0 0 rg BT 437.13 274.25 Td (contractual ) Tj ET Q q 0 0 0 rg BT 483.97 274.25 Td (or ) Tj ET Q q 0 0 0 rg BT 494.72 274.25 Td (legislative ) Tj ET Q q 0 0 0 rg BT 538.23 274.25 Td (discounts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 262.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.54 262.25 Td (rebates. ) Tj ET Q q 0 0 0 rg BT 87.46 262.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 111.11 262.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 161.99 262.25 Td (are ) Tj ET Q q 0 0 0 rg BT 177.30 262.25 Td (increasing ) Tj ET Q q 0 0 0 rg BT 221.49 262.25 Td (at ) Tj ET Q q 0 0 0 rg BT 231.81 262.25 Td (a ) Tj ET Q q 0 0 0 rg BT 239.35 262.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 268.00 262.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 286.09 262.25 Td (than ) Tj ET Q q 0 0 0 rg BT 306.41 262.25 Td (gross ) Tj ET Q q 0 0 0 rg BT 330.62 262.25 Td (product ) Tj ET Q q 0 0 0 rg BT 364.27 262.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 386.81 262.25 Td (due ) Tj ET Q q 0 0 0 rg BT 404.35 262.25 Td (to ) Tj ET Q q 0 0 0 rg BT 415.23 262.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 443.88 262.25 Td (U.S. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 464.77 262.25 Td (Eliquis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.20 262.25 Td (gross ) Tj ET Q q 0 0 0 rg BT 520.42 262.25 Td (product ) Tj ET Q q 0 0 0 rg BT 554.07 262.25 Td (sales, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 250.25 Td (which ) Tj ET Q q 0 0 0 rg BT 62.89 250.25 Td (has ) Tj ET Q q 0 0 0 rg BT 78.68 250.25 Td (a ) Tj ET Q q 0 0 0 rg BT 85.57 250.25 Td (relatively ) Tj ET Q q 0 0 0 rg BT 125.78 250.25 Td (high ) Tj ET Q q 0 0 0 rg BT 146.01 250.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 169.02 250.25 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 215.35 250.25 Td (percentage ) Tj ET Q q 0 0 0 rg BT 261.11 250.25 Td (as ) Tj ET Q q 0 0 0 rg BT 271.89 250.25 Td (a ) Tj ET Q q 0 0 0 rg BT 278.78 250.25 Td (result ) Tj ET Q q 0 0 0 rg BT 303.45 250.25 Td (of ) Tj ET Q q 0 0 0 rg BT 314.24 250.25 Td (competitive ) Tj ET Q q 0 0 0 rg BT 363.90 250.25 Td (pressures ) Tj ET Q q 0 0 0 rg BT 403.56 250.25 Td (to ) Tj ET Q q 0 0 0 rg BT 413.80 250.25 Td (maintain ) Tj ET Q q 0 0 0 rg BT 451.24 250.25 Td (its ) Tj ET Q q 0 0 0 rg BT 463.14 250.25 Td (position ) Tj ET Q q 0 0 0 rg BT 497.82 250.25 Td (on ) Tj ET Q q 0 0 0 rg BT 510.27 250.25 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 553.81 250.25 Td (payer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 238.25 Td (formularies ) Tj ET Q q 0 0 0 rg BT 84.59 238.25 Td (allowing ) Tj ET Q q 0 0 0 rg BT 122.09 238.25 Td (patients ) Tj ET Q q 0 0 0 rg BT 155.69 238.25 Td (continued ) Tj ET Q q 0 0 0 rg BT 197.63 238.25 Td (access ) Tj ET Q q 0 0 0 rg BT 225.66 238.25 Td (through ) Tj ET Q q 0 0 0 rg BT 259.27 238.25 Td (their ) Tj ET Q q 0 0 0 rg BT 280.10 238.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 314.25 238.25 Td (plans.) Tj ET Q endstream endobj 71 0 obj <> endobj 72 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (35) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Product ) Tj ET Q q 0 0 0 rg BT 71.28 749.25 Td (Revenues) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 704.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 704.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 704.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 704.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 704.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 704.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 704.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 704.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 704.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 704.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 704.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 678.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 678.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 678.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 678.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 678.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 678.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 678.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 678.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 678.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 678.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 678.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 652.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 652.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 652.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 652.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 652.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 652.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 652.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 652.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 652.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 652.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 652.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 632.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 632.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 632.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 632.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 632.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 632.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 632.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 632.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 632.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 632.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 632.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 606.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 606.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 606.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 606.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 606.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 606.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 606.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 606.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 606.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 606.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 606.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 586.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 586.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 586.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 586.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 586.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 586.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 586.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 586.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 586.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 586.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 586.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 560.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 560.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 560.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 560.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 560.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 560.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 560.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 560.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 560.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 560.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 560.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 540.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 540.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 540.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 540.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 540.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 540.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 540.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 540.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 540.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 540.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 540.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 514.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 514.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 514.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 514.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 514.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 514.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 514.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 514.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 514.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 514.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 514.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 494.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 494.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 494.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 494.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 494.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 494.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 494.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 494.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 494.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 494.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 494.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 468.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 468.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 468.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 468.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 468.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 468.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 468.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 468.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 468.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 468.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 468.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 448.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 448.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 448.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 448.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 448.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 448.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 448.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 448.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 448.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 448.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 448.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 422.75 275.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 422.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 422.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 422.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 422.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 422.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 422.75 43.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 422.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 422.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 422.75 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 422.75 58.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 402.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 402.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 402.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 402.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 402.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 402.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 402.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 402.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 402.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 402.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 402.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 376.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 376.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 376.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 376.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 376.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 376.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 376.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 376.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 376.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 376.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 376.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 356.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 356.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 356.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 356.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 356.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 356.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 356.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 356.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 356.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 356.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 356.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 330.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 330.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 330.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 330.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 330.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 330.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 330.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 330.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 330.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 330.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 330.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 310.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 310.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 310.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 310.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 310.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 310.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 310.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 310.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 310.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 310.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 310.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 284.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 284.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 284.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 284.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 284.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 284.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 284.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 284.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 284.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 284.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 284.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 264.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 264.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 264.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 264.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 264.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 264.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 264.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 264.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 264.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 264.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 264.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 238.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 238.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 238.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 238.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 238.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 238.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 238.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 238.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 238.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 238.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 238.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 218.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 218.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 218.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 218.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 218.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 218.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 218.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 218.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 218.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 218.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 218.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 192.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 192.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 192.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 192.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 192.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 192.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 192.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 192.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 192.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 192.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 192.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 172.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 172.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 172.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 172.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 172.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 172.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 172.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 172.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 172.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 172.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 172.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 146.75 275.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 146.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 315.50 146.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 358.50 146.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 362.50 146.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 405.50 146.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 146.75 43.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 146.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 456.50 146.75 58.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 146.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 146.75 58.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 315.5 717.75 m 358.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 358.5 717.75 m 362.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 362.5 717.75 m 405.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 405.5 717.75 m 409.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 409.5 717.75 m 452.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 456.5 717.75 m 514.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 514.5 717.75 m 518.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 717.75 m 576.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 315.5 704.75 m 358.5 704.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 362.5 704.75 m 405.5 704.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 409.5 704.75 m 452.5 704.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 456.5 717.75 m 514.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 456.5 704.75 m 514.5 704.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 717.75 m 576.5 717.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 704.75 m 576.5 704.75 l s BT /F1 8.50 Tf ET q 0 0 0 rg BT 39.00 722.11 Td ( ) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 336.40 722.09 Td (Y) Tj ET Q q 0 0 0 rg BT 342.07 722.09 Td (ear) Tj ET Q q 0 0 0 rg BT 353.32 722.09 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 417.85 722.09 Td ( 31,) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 496.75 722.09 Td (% Change) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 39.00 709.11 Td (Dollars in Millions) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 328.00 709.09 Td (2017) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 375.00 709.09 Td (2016) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 422.00 709.09 Td (2015) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 461.00 709.09 Td (2017 vs. 2016) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 523.00 709.09 Td (2016 vs. 2015) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 39.00 696.15 Td (Prioritized Brands) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 683.00 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 318.00 683.01 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 683.01 Td (4,948) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 365.00 683.01 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 683.01 Td (3,774) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 412.00 683.01 Td ($) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 683.01 Td (942) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 683.01 Td (31) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 683.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 683.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 670.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 670.01 Td (3,102) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 670.01 Td (2,664) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 670.01 Td (823) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 670.01 Td (16) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 670.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 670.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 657.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 657.01 Td (1,846) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 657.01 Td (1,1) Tj ET Q q 0 0 0 rg BT 393.00 657.01 Td (10) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 657.01 Td (1) Tj ET Q q 0 0 0 rg BT 440.00 657.01 Td (19) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 657.01 Td (66) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 657.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 657.01 Td (**) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 637.00 Td (Eliquis) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 637.01 Td (4,872) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 637.01 Td (3,343) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 637.01 Td (1,860) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 637.01 Td (46) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 637.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 637.01 Td (80) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 637.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 624.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 624.01 Td (2,887) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 624.01 Td (1,963) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 624.01 Td (1,023) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 624.01 Td (47) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 624.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 624.01 Td (92) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 624.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 611.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 611.01 Td (1,985) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 611.01 Td (1,380) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 611.01 Td (837) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 611.01 Td (44) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 611.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 611.01 Td (65) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 611.01 Td (%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 591.00 Td (Or) Tj ET Q q 0 0 0 rg BT 48.83 591.00 Td (encia) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 591.01 Td (2,479) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 591.01 Td (2,265) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 591.01 Td (1,885) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.00 591.01 Td (9) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 591.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 591.01 Td (20) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 591.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 578.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 578.01 Td (1,704) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 578.01 Td (1,532) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 578.01 Td (1,271) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 578.01 Td (1) Tj ET Q q 0 0 0 rg BT 499.00 578.01 Td (1) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 578.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 578.01 Td (21) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 578.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 565.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 565.01 Td (775) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 565.01 Td (733) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 565.01 Td (614) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.00 565.01 Td (6) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 565.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 565.01 Td (19) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 565.01 Td (%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 545.00 Td (Sprycel) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 545.01 Td (2,005) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 545.01 Td (1,824) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 545.01 Td (1,620) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 545.01 Td (10) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 545.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 545.01 Td (13) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 545.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 532.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 532.01 Td (1,105) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 532.01 Td (969) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 532.01 Td (829) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 532.01 Td (14) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 532.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 532.01 Td (17) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 532.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 519.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 519.01 Td (900) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 519.01 Td (855) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 519.01 Td (791) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.00 519.01 Td (5) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 519.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 561.00 519.01 Td (8) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 519.01 Td (%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 499.00 Td (Y) Tj ET Q q 0 0 0 rg BT 43.59 499.00 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 499.01 Td (1,244) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 499.01 Td (1,053) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 499.01 Td (1,126) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 499.01 Td (18) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 499.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 558.00 499.01 Td (\(6) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 499.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 486.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 486.01 Td (908) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 486.01 Td (802) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 486.01 Td (602) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 486.01 Td (13) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 486.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 556.50 486.01 Td (33) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 568.50 486.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 473.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 473.01 Td (336) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 473.01 Td (251) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 473.01 Td (524) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 473.01 Td (34) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 473.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 473.01 Td (\(52) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 473.01 Td (\)%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 453.00 Td (Empliciti) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 453.01 Td (231) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 453.01 Td (150) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 444.50 453.01 Td (3) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 453.01 Td (54) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 453.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 453.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 440.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 440.01 Td (151) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 440.01 Td (133) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 444.50 440.01 Td (3) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 494.50 440.01 Td (14) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 440.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 440.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 427.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 346.00 427.01 Td (80) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 393.00 427.01 Td (17) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 440.00 427.01 Td (—) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 502.00 427.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 557.95 427.01 Td (N/A) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 39.00 407.15 Td (Established Brands) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 394.00 Td (Baraclude) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 394.01 Td (1,052) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 394.01 Td (1,192) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 394.01 Td (1,312) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 394.01 Td (\(12) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 394.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 558.00 394.01 Td (\(9) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 394.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 381.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 346.00 381.01 Td (53) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 393.00 381.01 Td (66) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 381.01 Td (135) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 381.01 Td (\(20) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 381.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 381.01 Td (\(51) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 381.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 368.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 368.01 Td (999) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 368.01 Td (1,126) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 368.01 Td (1,177) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 368.01 Td (\(1) Tj ET Q q 0 0 0 rg BT 499.00 368.01 Td (1) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 368.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 558.00 368.01 Td (\(4) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 368.01 Td (\)%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 348.00 Td (Sustiva Franchise) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 348.01 Td (729) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 348.01 Td (1,065) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 348.01 Td (1,252) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 348.01 Td (\(32) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 348.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 348.01 Td (\(15) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 348.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 335.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 335.01 Td (622) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 335.01 Td (901) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 335.01 Td (1,041) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 335.01 Td (\(31) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 335.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 335.01 Td (\(13) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 335.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 322.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 322.01 Td (107) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 322.01 Td (164) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 322.01 Td (21) Tj ET Q q 0 0 0 rg BT 444.50 322.01 Td (1) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 322.01 Td (\(35) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 322.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 322.01 Td (\(22) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 322.01 Td (\)%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 39.00 302.00 Td (Reyataz Franchise) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 302.01 Td (698) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 302.01 Td (912) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 302.01 Td (1,139) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 302.01 Td (\(23) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 302.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 302.01 Td (\(20) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 302.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 289.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 289.01 Td (327) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 289.01 Td (484) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 289.01 Td (591) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 289.01 Td (\(32) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 289.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 289.01 Td (\(18) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 289.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 276.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 276.01 Td (371) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 276.01 Td (428) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 276.01 Td (548) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 276.01 Td (\(13) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 276.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 276.01 Td (\(22) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 276.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 39.00 256.01 Td (Hepatitis C Franchise) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 256.01 Td (406) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 256.01 Td (1,578) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 256.01 Td (1,603) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 256.01 Td (\(74) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 256.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 558.00 256.01 Td (\(2) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 256.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 243.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 243.01 Td (109) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 243.01 Td (827) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 435.50 243.01 Td (323) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 243.01 Td (\(87) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 243.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 564.00 243.01 Td (**) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 230.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 230.01 Td (297) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 230.01 Td (751) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 230.01 Td (1,280) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 491.50 230.01 Td (\(60) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 230.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 230.01 Td (\(41) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 230.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 39.00 210.01 Td (Other Brands) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 210.01 Td (2,1) Tj ET Q q 0 0 0 rg BT 346.00 210.01 Td (12) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 210.01 Td (2,271) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 210.01 Td (3,818) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 496.00 210.01 Td (\(7) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 210.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 210.01 Td (\(41) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 210.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 197.01 Td (U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 341.50 197.01 Td (390) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 388.50 197.01 Td (379) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 197.01 Td (1,547) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 499.00 197.01 Td (3) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 506.50 197.01 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 197.01 Td (\(76) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 197.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 57.00 184.01 Td (Non-U.S.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 184.01 Td (1,722) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 381.75 184.01 Td (1,892) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 428.75 184.01 Td (2,271) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 496.00 184.01 Td (\(9) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 503.50 184.01 Td (\)%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 553.50 184.01 Td (\(17) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 565.50 184.01 Td (\)%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 39.00 164.15 Td (T) Tj ET Q q 0 0 0 rg BT 44.18 164.15 Td (otal Revenues) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 330.25 164.15 Td (20,776) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 377.25 164.15 Td (19,427) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 424.25 164.15 Td (16,560) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 499.00 164.15 Td (7) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 505.00 164.15 Td (%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 556.50 164.15 Td (17) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 567.00 164.15 Td (%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 57.00 151.15 Td (U.S.) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 330.25 151.15 Td (1) Tj ET Q q 0 0 0 rg BT 334.75 151.15 Td (1,358) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 377.25 151.15 Td (10,720) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 428.75 151.15 Td (8,188) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 499.00 151.15 Td (6) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 505.00 151.15 Td (%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 556.50 151.15 Td (31) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 567.00 151.15 Td (%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 57.00 138.15 Td (Non-U.S.) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 334.75 138.15 Td (9,418) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 381.75 138.15 Td (8,707) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 428.75 138.15 Td (8,372) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 499.00 138.15 Td (8) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 505.00 138.15 Td (%) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 561.00 138.15 Td (4) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 567.00 138.15 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 124.65 Td (** ) Tj ET Q q 0 0 0 rg BT 58.50 124.65 Td (Change ) Tj ET Q q 0 0 0 rg BT 84.94 124.65 Td (in ) Tj ET Q q 0 0 0 rg BT 93.16 124.65 Td (excess ) Tj ET Q q 0 0 0 rg BT 116.04 124.65 Td (of ) Tj ET Q q 0 0 0 rg BT 124.70 124.65 Td (100%) Tj ET Q endstream endobj 73 0 obj <> endobj 74 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (36) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Opdivo ) Tj ET Q q 0 0 0 rg BT 67.48 749.10 Td (\(nivolumab\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 116.36 749.10 Td ( — a ) Tj ET Q q 0 0 0 rg BT 137.84 749.10 Td (fully ) Tj ET Q q 0 0 0 rg BT 158.76 749.10 Td (human ) Tj ET Q q 0 0 0 rg BT 188.02 749.10 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 237.27 749.10 Td (antibody ) Tj ET Q q 0 0 0 rg BT 274.31 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 291.35 749.10 Td (binds ) Tj ET Q q 0 0 0 rg BT 315.06 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 324.88 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 339.13 749.10 Td (PD-1 ) Tj ET Q q 0 0 0 rg BT 362.29 749.10 Td (on ) Tj ET Q q 0 0 0 rg BT 374.18 749.10 Td (T) Tj ET Q q 0 0 0 rg BT 380.11 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 382.15 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 398.63 749.10 Td (NKT) Tj ET Q q 0 0 0 rg BT 419.00 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 421.04 749.10 Td (cells ) Tj ET Q q 0 0 0 rg BT 441.41 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 458.45 749.10 Td (has ) Tj ET Q q 0 0 0 rg BT 473.82 749.10 Td (been ) Tj ET Q q 0 0 0 rg BT 494.73 749.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 533.98 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 547.68 749.10 Td (several ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (anti-cancer ) Tj ET Q q 0 0 0 rg BT 83.08 737.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 129.63 737.10 Td (including ) Tj ET Q q 0 0 0 rg BT 170.07 737.10 Td (bladder) Tj ET Q q 0 0 0 rg BT 199.65 737.10 Td (, ) Tj ET Q q 0 0 0 rg BT 204.82 737.10 Td (blood, ) Tj ET Q q 0 0 0 rg BT 232.77 737.10 Td (colon, ) Tj ET Q q 0 0 0 rg BT 260.15 737.10 Td (head ) Tj ET Q q 0 0 0 rg BT 281.69 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 298.80 737.10 Td (neck, ) Tj ET Q q 0 0 0 rg BT 322.84 737.10 Td (kidney) Tj ET Q q 0 0 0 rg BT 349.41 737.10 Td (, ) Tj ET Q q 0 0 0 rg BT 354.58 737.10 Td (liver) Tj ET Q q 0 0 0 rg BT 372.50 737.10 Td (, ) Tj ET Q q 0 0 0 rg BT 377.67 737.10 Td (lung, ) Tj ET Q q 0 0 0 rg BT 400.62 737.10 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 444.94 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 462.04 737.10 Td (stomach ) Tj ET Q q 0 0 0 rg BT 498.03 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 515.14 737.10 Td (continues ) Tj ET Q q 0 0 0 rg BT 556.13 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 566.58 737.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (investigated ) Tj ET Q q 0 0 0 rg BT 86.82 725.10 Td (across ) Tj ET Q q 0 0 0 rg BT 114.31 725.10 Td (other ) Tj ET Q q 0 0 0 rg BT 137.36 725.10 Td (tumor ) Tj ET Q q 0 0 0 rg BT 163.74 725.10 Td (types ) Tj ET Q q 0 0 0 rg BT 187.35 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 204.29 725.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 235.67 725.10 Td (areas.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 709.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 709.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 73.90 709.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 111.55 709.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 151.42 709.10 Td (in ) Tj ET Q q 0 0 0 rg BT 161.31 709.10 Td (both ) Tj ET Q q 0 0 0 rg BT 181.20 709.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 212.75 709.10 Td (due ) Tj ET Q q 0 0 0 rg BT 229.31 709.10 Td (to ) Tj ET Q q 0 0 0 rg BT 239.20 709.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 266.86 709.10 Td (demand. ) Tj ET Q q 0 0 0 rg BT 302.98 709.10 Td (W) Tj ET Q q 0 0 0 rg BT 311.62 709.10 Td (e ) Tj ET Q q 0 0 0 rg BT 318.17 709.10 Td (expect ) Tj ET Q q 0 0 0 rg BT 346.38 709.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 386.24 709.10 Td (competition ) Tj ET Q q 0 0 0 rg BT 436.13 709.10 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 449.90 709.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.34 709.10 Td ( ) Tj ET Q q 0 0 0 rg BT 481.45 709.10 Td (to ) Tj ET Q q 0 0 0 rg BT 491.35 709.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 527.90 709.10 Td (in ) Tj ET Q q 0 0 0 rg BT 537.79 709.10 Td (the ) Tj ET Q q 0 0 0 rg BT 552.12 709.10 Td (future ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 697.10 Td (due ) Tj ET Q q 0 0 0 rg BT 70.94 697.10 Td (to ) Tj ET Q q 0 0 0 rg BT 81.22 697.10 Td (new ) Tj ET Q q 0 0 0 rg BT 100.38 697.10 Td (product ) Tj ET Q q 0 0 0 rg BT 133.42 697.10 Td (entrants ) Tj ET Q q 0 0 0 rg BT 167.58 697.10 Td (and ) Tj ET Q q 0 0 0 rg BT 184.52 697.10 Td (expanded ) Tj ET Q q 0 0 0 rg BT 225.33 697.10 Td (indications.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 681.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 681.10 Td (International ) Tj ET Q q 0 0 0 rg BT 107.16 681.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 144.77 681.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 184.60 681.10 Td (in ) Tj ET Q q 0 0 0 rg BT 194.45 681.10 Td (both ) Tj ET Q q 0 0 0 rg BT 214.30 681.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 245.81 681.10 Td (due ) Tj ET Q q 0 0 0 rg BT 262.32 681.10 Td (to ) Tj ET Q q 0 0 0 rg BT 272.17 681.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 299.79 681.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 333.52 681.10 Td (as ) Tj ET Q q 0 0 0 rg BT 343.92 681.10 Td (a ) Tj ET Q q 0 0 0 rg BT 350.44 681.10 Td (result ) Tj ET Q q 0 0 0 rg BT 374.73 681.10 Td (of ) Tj ET Q q 0 0 0 rg BT 385.13 681.10 Td (launches ) Tj ET Q q 0 0 0 rg BT 422.19 681.10 Td (of ) Tj ET Q q 0 0 0 rg BT 432.59 681.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 474.65 681.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 520.61 681.10 Td (and ) Tj ET Q q 0 0 0 rg BT 537.12 681.10 Td (approvals ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 669.10 Td (in ) Tj ET Q q 0 0 0 rg BT 64.28 669.10 Td (new ) Tj ET Q q 0 0 0 rg BT 83.44 669.10 Td (countries.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 649.10 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.33 649.10 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 66.82 649.10 Td (\(apixaban\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 113.17 649.10 Td (— ) Tj ET Q q 0 0 0 rg BT 125.65 649.10 Td (an ) Tj ET Q q 0 0 0 rg BT 137.57 649.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 155.60 649.10 Td (Factor ) Tj ET Q q 0 0 0 rg BT 183.63 649.10 Td (Xa ) Tj ET Q q 0 0 0 rg BT 197.77 649.10 Td (inhibitor) Tj ET Q q 0 0 0 rg BT 231.81 649.10 Td (, ) Tj ET Q q 0 0 0 rg BT 236.79 649.10 Td (tar) Tj ET Q q 0 0 0 rg BT 247.16 649.10 Td (geted ) Tj ET Q q 0 0 0 rg BT 271.29 649.10 Td (at ) Tj ET Q q 0 0 0 rg BT 280.99 649.10 Td (stroke ) Tj ET Q q 0 0 0 rg BT 307.91 649.10 Td (prevention ) Tj ET Q q 0 0 0 rg BT 353.15 649.10 Td (in ) Tj ET Q q 0 0 0 rg BT 363.41 649.10 Td (adult ) Tj ET Q q 0 0 0 rg BT 385.89 649.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 419.47 649.10 Td (with ) Tj ET Q q 0 0 0 rg BT 439.73 649.10 Td (non-valvular ) Tj ET Q q 0 0 0 rg BT 493.30 649.10 Td (atrial ) Tj ET Q q 0 0 0 rg BT 516.33 649.10 Td (fibrillation ) Tj ET Q q 0 0 0 rg BT 561.58 649.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 637.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 637.10 Td (prevention ) Tj ET Q q 0 0 0 rg BT 95.98 637.10 Td (and ) Tj ET Q q 0 0 0 rg BT 112.92 637.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 153.18 637.10 Td (of ) Tj ET Q q 0 0 0 rg BT 163.83 637.10 Td (VTE ) Tj ET Q q 0 0 0 rg BT 185.77 637.10 Td (disorders.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 621.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.14 621.10 Td (and ) Tj ET Q q 0 0 0 rg BT 90.93 621.10 Td (international ) Tj ET Q q 0 0 0 rg BT 143.82 621.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 181.71 621.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 221.81 621.10 Td (in ) Tj ET Q q 0 0 0 rg BT 231.94 621.10 Td (both ) Tj ET Q q 0 0 0 rg BT 252.07 621.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 283.87 621.10 Td (due ) Tj ET Q q 0 0 0 rg BT 300.66 621.10 Td (to ) Tj ET Q q 0 0 0 rg BT 310.79 621.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 338.69 621.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 372.69 621.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 410.04 621.10 Td (from ) Tj ET Q q 0 0 0 rg BT 431.83 621.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 471.94 621.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 521.49 621.10 Td (acceptance ) Tj ET Q q 0 0 0 rg BT 567.69 621.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 609.10 Td (novel ) Tj ET Q q 0 0 0 rg BT 78.72 609.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 96.76 609.10 Td (anticoagulants ) Tj ET Q q 0 0 0 rg BT 157.02 609.10 Td (and ) Tj ET Q q 0 0 0 rg BT 173.96 609.10 Td (market ) Tj ET Q q 0 0 0 rg BT 204.22 609.10 Td (share ) Tj ET Q q 0 0 0 rg BT 227.82 609.10 Td (gains. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 589.10 Td (Or) Tj ET Q q 0 0 0 rg BT 46.74 589.10 Td (encia ) Tj ET Q q 0 0 0 rg BT 70.79 589.10 Td (\(abatacept\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 116.89 589.10 Td ( ) Tj ET Q q 0 0 0 rg BT 119.29 589.10 Td (— ) Tj ET Q q 0 0 0 rg BT 131.68 589.10 Td (a ) Tj ET Q q 0 0 0 rg BT 138.52 589.10 Td (fusion ) Tj ET Q q 0 0 0 rg BT 165.92 589.10 Td (protein ) Tj ET Q q 0 0 0 rg BT 196.64 589.10 Td (indicated ) Tj ET Q q 0 0 0 rg BT 235.69 589.10 Td (for ) Tj ET Q q 0 0 0 rg BT 249.75 589.10 Td (adult ) Tj ET Q q 0 0 0 rg BT 272.14 589.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 305.64 589.10 Td (with ) Tj ET Q q 0 0 0 rg BT 325.81 589.10 Td (moderate ) Tj ET Q q 0 0 0 rg BT 365.41 589.10 Td (to ) Tj ET Q q 0 0 0 rg BT 375.59 589.10 Td (severe ) Tj ET Q q 0 0 0 rg BT 403.52 589.10 Td (active ) Tj ET Q q 0 0 0 rg BT 429.79 589.10 Td (RA) Tj ET Q q 0 0 0 rg BT 443.13 589.10 Td ( ) Tj ET Q q 0 0 0 rg BT 445.53 589.10 Td (and ) Tj ET Q q 0 0 0 rg BT 462.37 589.10 Td (PsA) Tj ET Q q 0 0 0 rg BT 478.49 589.10 Td ( ) Tj ET Q q 0 0 0 rg BT 480.89 589.10 Td (and ) Tj ET Q q 0 0 0 rg BT 497.72 589.10 Td (is ) Tj ET Q q 0 0 0 rg BT 506.79 589.10 Td (also ) Tj ET Q q 0 0 0 rg BT 525.30 589.10 Td (indicated ) Tj ET Q q 0 0 0 rg BT 564.34 589.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 577.10 Td (reducing ) Tj ET Q q 0 0 0 rg BT 73.49 577.10 Td (signs ) Tj ET Q q 0 0 0 rg BT 96.55 577.10 Td (and ) Tj ET Q q 0 0 0 rg BT 113.49 577.10 Td (symptoms ) Tj ET Q q 0 0 0 rg BT 157.10 577.10 Td (in ) Tj ET Q q 0 0 0 rg BT 167.38 577.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 197.08 577.10 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 234.56 577.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 268.17 577.10 Td (with ) Tj ET Q q 0 0 0 rg BT 288.45 577.10 Td (moderately ) Tj ET Q q 0 0 0 rg BT 335.93 577.10 Td (to ) Tj ET Q q 0 0 0 rg BT 346.21 577.10 Td (severely ) Tj ET Q q 0 0 0 rg BT 382.02 577.10 Td (active ) Tj ET Q q 0 0 0 rg BT 408.39 577.10 Td (polyarticular ) Tj ET Q q 0 0 0 rg BT 461.98 577.10 Td (juvenile ) Tj ET Q q 0 0 0 rg BT 496.69 577.10 Td (idiopathic ) Tj ET Q q 0 0 0 rg BT 539.18 577.10 Td (arthritis.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 561.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 561.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.28 561.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.32 561.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 152.57 561.10 Td (in ) Tj ET Q q 0 0 0 rg BT 162.85 561.10 Td (both ) Tj ET Q q 0 0 0 rg BT 183.13 561.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 215.07 561.10 Td (due ) Tj ET Q q 0 0 0 rg BT 232.01 561.10 Td (to ) Tj ET Q q 0 0 0 rg BT 242.29 561.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 270.33 561.10 Td (average ) Tj ET Q q 0 0 0 rg BT 303.92 561.10 Td (net ) Tj ET Q q 0 0 0 rg BT 318.63 561.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 347.80 561.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 374.18 561.10 Td (and ) Tj ET Q q 0 0 0 rg BT 391.11 561.10 Td (demand.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 546.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 546.10 Td (International ) Tj ET Q q 0 0 0 rg BT 107.59 546.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 145.63 546.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 185.88 546.10 Td (in ) Tj ET Q q 0 0 0 rg BT 196.16 546.10 Td (both ) Tj ET Q q 0 0 0 rg BT 216.44 546.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 248.38 546.10 Td (due ) Tj ET Q q 0 0 0 rg BT 265.31 546.10 Td (to ) Tj ET Q q 0 0 0 rg BT 275.59 546.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 303.64 546.10 Td (demand.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 526.10 Td (Sprycel ) Tj ET Q q 0 0 0 rg BT 69.71 526.10 Td (\(dasatinib\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 113.60 526.10 Td ( — an ) Tj ET Q q 0 0 0 rg BT 141.76 526.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 161.03 526.10 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 199.19 526.10 Td (of ) Tj ET Q q 0 0 0 rg BT 211.25 526.10 Td (multiple ) Tj ET Q q 0 0 0 rg BT 248.30 526.10 Td (tyrosine ) Tj ET Q q 0 0 0 rg BT 284.24 526.10 Td (kinase ) Tj ET Q q 0 0 0 rg BT 313.51 526.10 Td (indicated ) Tj ET Q q 0 0 0 rg BT 353.88 526.10 Td (for ) Tj ET Q q 0 0 0 rg BT 369.27 526.10 Td (the ) Tj ET Q q 0 0 0 rg BT 385.21 526.10 Td (first-line ) Tj ET Q q 0 0 0 rg BT 423.36 526.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 464.85 526.10 Td (of ) Tj ET Q q 0 0 0 rg BT 476.90 526.10 Td (adults ) Tj ET Q q 0 0 0 rg BT 504.51 526.10 Td (with ) Tj ET Q q 0 0 0 rg BT 526.01 526.10 Td (Philadelphia ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 514.10 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 125.57 514.10 Td (chronic ) Tj ET Q q 0 0 0 rg BT 158.48 514.10 Td (myeloid ) Tj ET Q q 0 0 0 rg BT 194.17 514.10 Td (leukemia ) Tj ET Q q 0 0 0 rg BT 233.74 514.10 Td (in ) Tj ET Q q 0 0 0 rg BT 244.44 514.10 Td (chronic ) Tj ET Q q 0 0 0 rg BT 277.34 514.10 Td (phase ) Tj ET Q q 0 0 0 rg BT 303.03 514.10 Td (and ) Tj ET Q q 0 0 0 rg BT 320.39 514.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.53 514.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 376.21 514.10 Td (of ) Tj ET Q q 0 0 0 rg BT 387.46 514.10 Td (adults ) Tj ET Q q 0 0 0 rg BT 414.26 514.10 Td (with ) Tj ET Q q 0 0 0 rg BT 434.96 514.10 Td (chronic, ) Tj ET Q q 0 0 0 rg BT 470.37 514.10 Td (accelerated, ) Tj ET Q q 0 0 0 rg BT 520.74 514.10 Td (or ) Tj ET Q q 0 0 0 rg BT 531.99 514.10 Td (myeloid ) Tj ET Q q 0 0 0 rg BT 567.68 514.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 502.10 Td (lymphoid ) Tj ET Q q 0 0 0 rg BT 76.83 502.10 Td (blast ) Tj ET Q q 0 0 0 rg BT 98.22 502.10 Td (phase ) Tj ET Q q 0 0 0 rg BT 123.49 502.10 Td (CML) Tj ET Q q 0 0 0 rg BT 144.79 502.10 Td ( ) Tj ET Q q 0 0 0 rg BT 147.29 502.10 Td (with ) Tj ET Q q 0 0 0 rg BT 167.57 502.10 Td (resistance ) Tj ET Q q 0 0 0 rg BT 209.49 502.10 Td (or ) Tj ET Q q 0 0 0 rg BT 220.32 502.10 Td (intolerance ) Tj ET Q q 0 0 0 rg BT 267.24 502.10 Td (to ) Tj ET Q q 0 0 0 rg BT 277.52 502.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 299.46 502.10 Td (therapy) Tj ET Q q 0 0 0 rg BT 328.79 502.10 Td (, ) Tj ET Q q 0 0 0 rg BT 333.79 502.10 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 374.07 502.10 Td (Gleevec* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.76 502.10 Td (\(imatinib ) Tj ET Q q 0 0 0 rg BT 452.92 502.10 Td (meslylate\).) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 36.00 485.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 485.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.28 485.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.32 485.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 152.57 485.60 Td (in ) Tj ET Q q 0 0 0 rg BT 162.85 485.60 Td (both ) Tj ET Q q 0 0 0 rg BT 183.13 485.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 215.07 485.60 Td (due ) Tj ET Q q 0 0 0 rg BT 232.01 485.60 Td (to ) Tj ET Q q 0 0 0 rg BT 242.29 485.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 270.33 485.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 304.49 485.60 Td (and ) Tj ET Q q 0 0 0 rg BT 321.43 485.60 Td (average ) Tj ET Q q 0 0 0 rg BT 355.01 485.60 Td (net ) Tj ET Q q 0 0 0 rg BT 369.73 485.60 Td (selling ) Tj ET Q q 0 0 0 rg BT 398.89 485.60 Td (prices.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 470.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 470.60 Td (International ) Tj ET Q q 0 0 0 rg BT 107.85 470.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 146.14 470.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 186.65 470.60 Td (in ) Tj ET Q q 0 0 0 rg BT 197.18 470.60 Td (both ) Tj ET Q q 0 0 0 rg BT 217.72 470.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 249.91 470.60 Td (due ) Tj ET Q q 0 0 0 rg BT 267.11 470.60 Td (to ) Tj ET Q q 0 0 0 rg BT 277.64 470.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 305.95 470.60 Td (demand. ) Tj ET Q q 0 0 0 rg BT 342.66 470.60 Td (W) Tj ET Q q 0 0 0 rg BT 351.30 470.60 Td (e ) Tj ET Q q 0 0 0 rg BT 358.49 470.60 Td (may ) Tj ET Q q 0 0 0 rg BT 378.46 470.60 Td (experience ) Tj ET Q q 0 0 0 rg BT 424.52 470.60 Td (a ) Tj ET Q q 0 0 0 rg BT 431.72 470.60 Td (decline ) Tj ET Q q 0 0 0 rg BT 463.34 470.60 Td (in ) Tj ET Q q 0 0 0 rg BT 473.88 470.60 Td (European ) Tj ET Q q 0 0 0 rg BT 514.95 470.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 553.24 470.60 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 470.60 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 458.60 Td (event ) Tj ET Q q 0 0 0 rg BT 78.16 458.60 Td (that ) Tj ET Q q 0 0 0 rg BT 95.65 458.60 Td (generic ) Tj ET Q q 0 0 0 rg BT 127.57 458.60 Td (datasinib ) Tj ET Q q 0 0 0 rg BT 166.18 458.60 Td (product ) Tj ET Q q 0 0 0 rg BT 199.22 458.60 Td (enters ) Tj ET Q q 0 0 0 rg BT 225.60 458.60 Td (the ) Tj ET Q q 0 0 0 rg BT 240.32 458.60 Td (market.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 438.60 Td (Y) Tj ET Q q 0 0 0 rg BT 40.64 438.60 Td (ervoy ) Tj ET Q q 0 0 0 rg BT 65.35 438.60 Td (\(ipilimumab\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 117.57 438.60 Td ( — a ) Tj ET Q q 0 0 0 rg BT 139.51 438.60 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 189.22 438.60 Td (antibody ) Tj ET Q q 0 0 0 rg BT 226.71 438.60 Td (for ) Tj ET Q q 0 0 0 rg BT 240.87 438.60 Td (the ) Tj ET Q q 0 0 0 rg BT 255.59 438.60 Td (treatment ) Tj ET Q q 0 0 0 rg BT 295.85 438.60 Td (of ) Tj ET Q q 0 0 0 rg BT 306.68 438.60 Td (patients ) Tj ET Q q 0 0 0 rg BT 340.28 438.60 Td (with ) Tj ET Q q 0 0 0 rg BT 360.56 438.60 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 413.03 438.60 Td (or ) Tj ET Q q 0 0 0 rg BT 423.86 438.60 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 466.90 438.60 Td (melanoma.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 423.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 423.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.28 423.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.32 423.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 152.57 423.60 Td (in ) Tj ET Q q 0 0 0 rg BT 162.85 423.60 Td (both ) Tj ET Q q 0 0 0 rg BT 183.13 423.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 215.07 423.60 Td (primarily ) Tj ET Q q 0 0 0 rg BT 254.78 423.60 Td (due ) Tj ET Q q 0 0 0 rg BT 271.72 423.60 Td (to ) Tj ET Q q 0 0 0 rg BT 282.00 423.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 310.04 423.60 Td (demand.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 407.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 407.60 Td (International ) Tj ET Q q 0 0 0 rg BT 107.10 407.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 144.64 407.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 184.40 407.60 Td (in ) Tj ET Q q 0 0 0 rg BT 194.19 407.60 Td (2017 ) Tj ET Q q 0 0 0 rg BT 216.19 407.60 Td (due ) Tj ET Q q 0 0 0 rg BT 232.64 407.60 Td (to ) Tj ET Q q 0 0 0 rg BT 242.42 407.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 269.98 407.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 303.64 407.60 Td (in ) Tj ET Q q 0 0 0 rg BT 313.42 407.60 Td (Europe ) Tj ET Q q 0 0 0 rg BT 344.31 407.60 Td (following ) Tj ET Q q 0 0 0 rg BT 385.20 407.60 Td (the ) Tj ET Q q 0 0 0 rg BT 399.42 407.60 Td (approval ) Tj ET Q q 0 0 0 rg BT 436.42 407.60 Td (of ) Tj ET Q q 0 0 0 rg BT 446.75 407.60 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 460.98 407.60 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 501.81 407.60 Td (ervoy ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 526.02 407.60 Td (combination ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 395.60 Td (therapy ) Tj ET Q q 0 0 0 rg BT 86.81 395.60 Td (for ) Tj ET Q q 0 0 0 rg BT 101.29 395.60 Td (melanoma. ) Tj ET Q q 0 0 0 rg BT 148.26 395.60 Td (International ) Tj ET Q q 0 0 0 rg BT 202.17 395.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 240.53 395.60 Td (decreased ) Tj ET Q q 0 0 0 rg BT 282.76 395.60 Td (in ) Tj ET Q q 0 0 0 rg BT 293.36 395.60 Td (2016 ) Tj ET Q q 0 0 0 rg BT 316.18 395.60 Td (due ) Tj ET Q q 0 0 0 rg BT 333.44 395.60 Td (to ) Tj ET Q q 0 0 0 rg BT 344.04 395.60 Td (lower ) Tj ET Q q 0 0 0 rg BT 369.63 395.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 404.11 395.60 Td (resulting ) Tj ET Q q 0 0 0 rg BT 441.93 395.60 Td (from ) Tj ET Q q 0 0 0 rg BT 464.19 395.60 Td (the ) Tj ET Q q 0 0 0 rg BT 479.22 395.60 Td (introduction ) Tj ET Q q 0 0 0 rg BT 530.93 395.60 Td (of ) Tj ET Q q 0 0 0 rg BT 542.08 395.60 Td (other ) Tj ET Q q 0 0 0 rg BT 565.45 395.60 Td (IO ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 383.60 Td (products ) Tj ET Q q 0 0 0 rg BT 90.94 383.60 Td (being ) Tj ET Q q 0 0 0 rg BT 115.66 383.60 Td (used ) Tj ET Q q 0 0 0 rg BT 136.49 383.60 Td (to ) Tj ET Q q 0 0 0 rg BT 146.76 383.60 Td (treat ) Tj ET Q q 0 0 0 rg BT 167.03 383.60 Td (patients ) Tj ET Q q 0 0 0 rg BT 200.63 383.60 Td (with ) Tj ET Q q 0 0 0 rg BT 220.91 383.60 Td (melanoma, ) Tj ET Q q 0 0 0 rg BT 267.56 383.60 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 307.83 383.60 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.27 383.60 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 363.60 Td (Empliciti ) Tj ET Q q 0 0 0 rg BT 75.16 363.60 Td (\(elotuzumab\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 127.93 363.60 Td ( ) Tj ET Q q 0 0 0 rg BT 130.43 363.60 Td (— ) Tj ET Q q 0 0 0 rg BT 142.93 363.60 Td (a ) Tj ET Q q 0 0 0 rg BT 149.87 363.60 Td (humanized ) Tj ET Q q 0 0 0 rg BT 196.24 363.60 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 245.95 363.60 Td (antibody ) Tj ET Q q 0 0 0 rg BT 283.45 363.60 Td (for ) Tj ET Q q 0 0 0 rg BT 297.61 363.60 Td (the ) Tj ET Q q 0 0 0 rg BT 312.32 363.60 Td (treatment ) Tj ET Q q 0 0 0 rg BT 352.58 363.60 Td (of ) Tj ET Q q 0 0 0 rg BT 363.41 363.60 Td (multiple ) Tj ET Q q 0 0 0 rg BT 399.24 363.60 Td (myeloma. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 345.60 Td (• ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 54.00 345.60 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 90.66 345.60 Td ( ) Tj ET Q q 0 0 0 rg BT 93.16 345.60 Td (was ) Tj ET Q q 0 0 0 rg BT 111.21 345.60 Td (launched ) Tj ET Q q 0 0 0 rg BT 149.81 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 160.08 345.60 Td (the ) Tj ET Q q 0 0 0 rg BT 174.80 345.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 195.08 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 205.36 345.60 Td (December ) Tj ET Q q 0 0 0 rg BT 248.95 345.60 Td (2015, ) Tj ET Q q 0 0 0 rg BT 273.95 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 284.22 345.60 Td (the ) Tj ET Q q 0 0 0 rg BT 298.94 345.60 Td (EU ) Tj ET Q q 0 0 0 rg BT 314.77 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 325.05 345.60 Td (May ) Tj ET Q q 0 0 0 rg BT 345.88 345.60 Td (2016 ) Tj ET Q q 0 0 0 rg BT 368.38 345.60 Td (and ) Tj ET Q q 0 0 0 rg BT 385.32 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 395.60 345.60 Td (Japan ) Tj ET Q q 0 0 0 rg BT 420.87 345.60 Td (in ) Tj ET Q q 0 0 0 rg BT 431.14 345.60 Td (September ) Tj ET Q q 0 0 0 rg BT 476.41 345.60 Td (2016.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 325.60 Td (Baraclude ) Tj ET Q q 0 0 0 rg BT 80.16 325.60 Td (\(entecavir\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 124.02 325.60 Td ( — an ) Tj ET Q q 0 0 0 rg BT 150.96 325.60 Td (oral ) Tj ET Q q 0 0 0 rg BT 169.00 325.60 Td (antiviral ) Tj ET Q q 0 0 0 rg BT 204.82 325.60 Td (agent ) Tj ET Q q 0 0 0 rg BT 228.98 325.60 Td (for ) Tj ET Q q 0 0 0 rg BT 243.14 325.60 Td (the ) Tj ET Q q 0 0 0 rg BT 257.86 325.60 Td (treatment ) Tj ET Q q 0 0 0 rg BT 298.11 325.60 Td (of ) Tj ET Q q 0 0 0 rg BT 308.94 325.60 Td (chronic ) Tj ET Q q 0 0 0 rg BT 341.43 325.60 Td (hepatitis ) Tj ET Q q 0 0 0 rg BT 377.81 325.60 Td (B.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 309.60 Td (International ) Tj ET Q q 0 0 0 rg BT 107.59 309.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 145.63 309.60 Td (continued ) Tj ET Q q 0 0 0 rg BT 187.56 309.60 Td (to ) Tj ET Q q 0 0 0 rg BT 197.84 309.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 234.75 309.60 Td (in ) Tj ET Q q 0 0 0 rg BT 245.03 309.60 Td (both ) Tj ET Q q 0 0 0 rg BT 265.31 309.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 297.25 309.60 Td (due ) Tj ET Q q 0 0 0 rg BT 314.19 309.60 Td (to ) Tj ET Q q 0 0 0 rg BT 324.46 309.60 Td (lower ) Tj ET Q q 0 0 0 rg BT 349.73 309.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 383.89 309.60 Td (resulting ) Tj ET Q q 0 0 0 rg BT 421.38 309.60 Td (from ) Tj ET Q q 0 0 0 rg BT 443.32 309.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 483.58 309.60 Td (competition.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 289.60 Td (Sustiva ) Tj ET Q q 0 0 0 rg BT 67.94 289.60 Td (\(efavir) Tj ET Q q 0 0 0 rg BT 94.22 289.60 Td (enz\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 110.88 289.60 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 113.93 289.60 Td (Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 154.47 289.60 Td ( — a ) Tj ET Q q 0 0 0 rg BT 176.96 289.60 Td (non-nucleoside ) Tj ET Q q 0 0 0 rg BT 241.10 289.60 Td (reverse ) Tj ET Q q 0 0 0 rg BT 273.02 289.60 Td (transcriptase ) Tj ET Q q 0 0 0 rg BT 326.60 289.60 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 364.09 289.60 Td (for ) Tj ET Q q 0 0 0 rg BT 378.80 289.60 Td (the ) Tj ET Q q 0 0 0 rg BT 394.06 289.60 Td (treatment ) Tj ET Q q 0 0 0 rg BT 434.87 289.60 Td (of ) Tj ET Q q 0 0 0 rg BT 446.25 289.60 Td (HIV) Tj ET Q q 0 0 0 rg BT 462.73 289.60 Td (, ) Tj ET Q q 0 0 0 rg BT 468.28 289.60 Td (which ) Tj ET Q q 0 0 0 rg BT 495.77 289.60 Td (includes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 532.14 289.60 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.03 289.60 Td (, ) Tj ET Q q 0 0 0 rg BT 566.58 289.60 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 277.60 Td (antiretroviral ) Tj ET Q q 0 0 0 rg BT 90.70 277.60 Td (drug, ) Tj ET Q q 0 0 0 rg BT 114.03 277.60 Td (and ) Tj ET Q q 0 0 0 rg BT 130.97 277.60 Td (bulk ) Tj ET Q q 0 0 0 rg BT 151.24 277.60 Td (efavirenz, ) Tj ET Q q 0 0 0 rg BT 193.44 277.60 Td (which ) Tj ET Q q 0 0 0 rg BT 220.38 277.60 Td (is ) Tj ET Q q 0 0 0 rg BT 229.54 277.60 Td (also ) Tj ET Q q 0 0 0 rg BT 248.15 277.60 Td (included ) Tj ET Q q 0 0 0 rg BT 285.09 277.60 Td (in ) Tj ET Q q 0 0 0 rg BT 295.37 277.60 Td (the ) Tj ET Q q 0 0 0 rg BT 310.08 277.60 Td (combination ) Tj ET Q q 0 0 0 rg BT 362.57 277.60 Td (therapy) Tj ET Q q 0 0 0 rg BT 391.91 277.60 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 396.91 277.60 Td (Atripla*.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 261.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 261.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.50 261.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.75 261.60 Td (continued ) Tj ET Q q 0 0 0 rg BT 154.89 261.60 Td (to ) Tj ET Q q 0 0 0 rg BT 165.38 261.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 202.51 261.60 Td (in ) Tj ET Q q 0 0 0 rg BT 213.00 261.60 Td (both ) Tj ET Q q 0 0 0 rg BT 233.49 261.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 265.64 261.60 Td (due ) Tj ET Q q 0 0 0 rg BT 282.79 261.60 Td (to ) Tj ET Q q 0 0 0 rg BT 293.28 261.60 Td (lower ) Tj ET Q q 0 0 0 rg BT 318.76 261.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 353.13 261.60 Td (resulting ) Tj ET Q q 0 0 0 rg BT 390.84 261.60 Td (from ) Tj ET Q q 0 0 0 rg BT 412.99 261.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 453.46 261.60 Td (competition ) Tj ET Q q 0 0 0 rg BT 503.94 261.60 Td (from ) Tj ET Q q 0 0 0 rg BT 526.09 261.60 Td (new ) Tj ET Q q 0 0 0 rg BT 545.46 261.60 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 249.60 Td (entrants. ) Tj ET Q q 0 0 0 rg BT 89.97 249.60 Td (The ) Tj ET Q q 0 0 0 rg BT 107.47 249.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 143.83 249.60 Td (in ) Tj ET Q q 0 0 0 rg BT 153.57 249.60 Td (2016 ) Tj ET Q q 0 0 0 rg BT 175.52 249.60 Td (was ) Tj ET Q q 0 0 0 rg BT 193.02 249.60 Td (partially ) Tj ET Q q 0 0 0 rg BT 228.30 249.60 Td (of) Tj ET Q q 0 0 0 rg BT 236.45 249.60 Td (fset ) Tj ET Q q 0 0 0 rg BT 252.84 249.60 Td (by ) Tj ET Q q 0 0 0 rg BT 264.79 249.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 292.29 249.60 Td (average ) Tj ET Q q 0 0 0 rg BT 325.33 249.60 Td (net ) Tj ET Q q 0 0 0 rg BT 339.50 249.60 Td (selling ) Tj ET Q q 0 0 0 rg BT 368.12 249.60 Td (prices. ) Tj ET Q q 0 0 0 rg BT 396.31 249.60 Td (The ) Tj ET Q q 0 0 0 rg BT 413.81 249.60 Td (LOE ) Tj ET Q q 0 0 0 rg BT 435.20 249.60 Td (occurred ) Tj ET Q q 0 0 0 rg BT 472.13 249.60 Td (in ) Tj ET Q q 0 0 0 rg BT 481.86 249.60 Td (December ) Tj ET Q q 0 0 0 rg BT 524.89 249.60 Td (2017. ) Tj ET Q q 0 0 0 rg BT 549.35 249.60 Td (Gilead ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 237.60 Td (terminated ) Tj ET Q q 0 0 0 rg BT 99.00 237.60 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 128.05 237.60 Td (participation ) Tj ET Q q 0 0 0 rg BT 180.83 237.60 Td (in ) Tj ET Q q 0 0 0 rg BT 190.84 237.60 Td (the ) Tj ET Q q 0 0 0 rg BT 205.30 237.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 225.32 237.60 Td (and ) Tj ET Q q 0 0 0 rg BT 241.99 237.60 Td (Canada ) Tj ET Q q 0 0 0 rg BT 274.22 237.60 Td (joint ) Tj ET Q q 0 0 0 rg BT 294.79 237.60 Td (venture ) Tj ET Q q 0 0 0 rg BT 327.01 237.60 Td (following ) Tj ET Q q 0 0 0 rg BT 368.14 237.60 Td (the ) Tj ET Q q 0 0 0 rg BT 382.59 237.60 Td (launch ) Tj ET Q q 0 0 0 rg BT 411.48 237.60 Td (of ) Tj ET Q q 0 0 0 rg BT 422.05 237.60 Td (a ) Tj ET Q q 0 0 0 rg BT 428.73 237.60 Td (generic ) Tj ET Q q 0 0 0 rg BT 460.39 237.60 Td (version ) Tj ET Q q 0 0 0 rg BT 492.07 237.60 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 502.63 237.60 Td (Sustiva ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.76 237.60 Td (in ) Tj ET Q q 0 0 0 rg BT 543.78 237.60 Td (the ) Tj ET Q q 0 0 0 rg BT 558.23 237.60 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 225.60 Td (As ) Tj ET Q q 0 0 0 rg BT 67.25 225.60 Td (a ) Tj ET Q q 0 0 0 rg BT 73.82 225.60 Td (result, ) Tj ET Q q 0 0 0 rg BT 100.68 225.60 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 129.63 225.60 Td (share ) Tj ET Q q 0 0 0 rg BT 152.86 225.60 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 163.33 225.60 Td (Atripla) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 191.67 225.60 Td (* ) Tj ET Q q 0 0 0 rg BT 198.80 225.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 236.48 225.60 Td (will ) Tj ET Q q 0 0 0 rg BT 254.17 225.60 Td (further ) Tj ET Q q 0 0 0 rg BT 283.51 225.60 Td (decline ) Tj ET Q q 0 0 0 rg BT 314.52 225.60 Td (during ) Tj ET Q q 0 0 0 rg BT 342.76 225.60 Td (the ) Tj ET Q q 0 0 0 rg BT 357.12 225.60 Td (next ) Tj ET Q q 0 0 0 rg BT 376.47 225.60 Td (three ) Tj ET Q q 0 0 0 rg BT 398.59 225.60 Td (years. ) Tj ET Q q 0 0 0 rg BT 424.33 225.60 Td (Refer ) Tj ET Q q 0 0 0 rg BT 448.67 225.60 Td (to ) Tj ET Q q 0 0 0 rg BT 458.58 225.60 Td ("Item ) Tj ET Q q 0 0 0 rg BT 483.13 225.60 Td (8. ) Tj ET Q q 0 0 0 rg BT 492.76 225.60 Td (Financial ) Tj ET Q q 0 0 0 rg BT 532.11 225.60 Td (Statements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 213.60 Td (—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.94 213.60 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 90.94 213.60 Td (. ) Tj ET Q q 0 0 0 rg BT 95.39 213.60 Td (Alliances" ) Tj ET Q q 0 0 0 rg BT 139.73 213.60 Td (for ) Tj ET Q q 0 0 0 rg BT 153.89 213.60 Td (further ) Tj ET Q q 0 0 0 rg BT 183.60 213.60 Td (discussion.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 193.60 Td (Reyataz ) Tj ET Q q 0 0 0 rg BT 70.42 193.60 Td (\(atazanavir ) Tj ET Q q 0 0 0 rg BT 119.30 193.60 Td (sulfate\) ) Tj ET Q q 0 0 0 rg BT 152.06 193.60 Td (Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 192.60 193.60 Td ( — Includes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 244.25 193.60 Td (Reyataz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 275.90 193.60 Td ( ) Tj ET Q q 0 0 0 rg BT 278.67 193.60 Td (- ) Tj ET Q q 0 0 0 rg BT 284.76 193.60 Td (a ) Tj ET Q q 0 0 0 rg BT 291.97 193.60 Td (protease ) Tj ET Q q 0 0 0 rg BT 328.05 193.60 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 365.26 193.60 Td (for ) Tj ET Q q 0 0 0 rg BT 379.69 193.60 Td (the ) Tj ET Q q 0 0 0 rg BT 394.67 193.60 Td (treatment ) Tj ET Q q 0 0 0 rg BT 435.19 193.60 Td (of ) Tj ET Q q 0 0 0 rg BT 446.29 193.60 Td (HIV) Tj ET Q q 0 0 0 rg BT 463.88 193.60 Td ( ) Tj ET Q q 0 0 0 rg BT 466.65 193.60 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 483.85 193.60 Td (Evotaz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.07 193.60 Td ( ) Tj ET Q q 0 0 0 rg BT 513.84 193.60 Td (\(atazanavir ) Tj ET Q q 0 0 0 rg BT 561.01 193.60 Td (300 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.60 Td (mg ) Tj ET Q q 0 0 0 rg BT 51.28 181.60 Td (and ) Tj ET Q q 0 0 0 rg BT 68.22 181.60 Td (cobicistat ) Tj ET Q q 0 0 0 rg BT 109.04 181.60 Td (150 ) Tj ET Q q 0 0 0 rg BT 126.54 181.60 Td (mg\) ) Tj ET Q q 0 0 0 rg BT 145.15 181.60 Td (- ) Tj ET Q q 0 0 0 rg BT 150.98 181.60 Td (a ) Tj ET Q q 0 0 0 rg BT 157.91 181.60 Td (combination ) Tj ET Q q 0 0 0 rg BT 210.40 181.60 Td (therapy ) Tj ET Q q 0 0 0 rg BT 242.89 181.60 Td (containing ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 287.60 181.60 Td (Reyataz) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 319.26 181.60 Td ( ) Tj ET Q q 0 0 0 rg BT 321.76 181.60 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 338.70 181.60 Td (T) Tj ET Q q 0 0 0 rg BT 343.51 181.60 Td (ybost* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.12 181.60 Td (\(cobicistat\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 166.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 166.60 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.32 166.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.39 166.60 Td (continued ) Tj ET Q q 0 0 0 rg BT 154.36 166.60 Td (to ) Tj ET Q q 0 0 0 rg BT 164.68 166.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 201.63 166.60 Td (due ) Tj ET Q q 0 0 0 rg BT 218.60 166.60 Td (to ) Tj ET Q q 0 0 0 rg BT 228.92 166.60 Td (lower ) Tj ET Q q 0 0 0 rg BT 254.22 166.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 288.42 166.60 Td (resulting ) Tj ET Q q 0 0 0 rg BT 325.95 166.60 Td (from ) Tj ET Q q 0 0 0 rg BT 347.92 166.60 Td (new ) Tj ET Q q 0 0 0 rg BT 367.12 166.60 Td (product ) Tj ET Q q 0 0 0 rg BT 400.20 166.60 Td (entrants. ) Tj ET Q q 0 0 0 rg BT 436.71 166.60 Td (The ) Tj ET Q q 0 0 0 rg BT 454.80 166.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 491.75 166.60 Td (in ) Tj ET Q q 0 0 0 rg BT 502.06 166.60 Td (2016 ) Tj ET Q q 0 0 0 rg BT 524.60 166.60 Td (was ) Tj ET Q q 0 0 0 rg BT 542.69 166.60 Td (partially ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 154.60 Td (of) Tj ET Q q 0 0 0 rg BT 62.15 154.60 Td (fset ) Tj ET Q q 0 0 0 rg BT 79.27 154.60 Td (by ) Tj ET Q q 0 0 0 rg BT 91.95 154.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 120.17 154.60 Td (average ) Tj ET Q q 0 0 0 rg BT 153.94 154.60 Td (net ) Tj ET Q q 0 0 0 rg BT 168.83 154.60 Td (selling ) Tj ET Q q 0 0 0 rg BT 198.18 154.60 Td (prices. ) Tj ET Q q 0 0 0 rg BT 227.04 154.60 Td (The ) Tj ET Q q 0 0 0 rg BT 245.27 154.60 Td (LOE ) Tj ET Q q 0 0 0 rg BT 267.39 154.60 Td (occurred ) Tj ET Q q 0 0 0 rg BT 305.04 154.60 Td (in ) Tj ET Q q 0 0 0 rg BT 315.50 154.60 Td (December ) Tj ET Q q 0 0 0 rg BT 359.26 154.60 Td (2017 ) Tj ET Q q 0 0 0 rg BT 381.94 154.60 Td (and ) Tj ET Q q 0 0 0 rg BT 399.06 154.60 Td (will ) Tj ET Q q 0 0 0 rg BT 417.30 154.60 Td (result ) Tj ET Q q 0 0 0 rg BT 442.19 154.60 Td (in ) Tj ET Q q 0 0 0 rg BT 452.65 154.60 Td (a ) Tj ET Q q 0 0 0 rg BT 459.77 154.60 Td (higher ) Tj ET Q q 0 0 0 rg BT 488.00 154.60 Td (decline ) Tj ET Q q 0 0 0 rg BT 519.55 154.60 Td (in ) Tj ET Q q 0 0 0 rg BT 530.01 154.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 568.22 154.60 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 142.60 Td (future ) Tj ET Q q 0 0 0 rg BT 80.38 142.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 112.32 142.60 Td (due ) Tj ET Q q 0 0 0 rg BT 129.25 142.60 Td (to ) Tj ET Q q 0 0 0 rg BT 139.53 142.60 Td (generic ) Tj ET Q q 0 0 0 rg BT 171.46 142.60 Td (competition.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 127.60 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 127.60 Td (International ) Tj ET Q q 0 0 0 rg BT 106.84 127.60 Td (revenues ) Tj ET Q q 0 0 0 rg BT 144.13 127.60 Td (continued ) Tj ET Q q 0 0 0 rg BT 185.32 127.60 Td (to ) Tj ET Q q 0 0 0 rg BT 194.86 127.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 231.02 127.60 Td (in ) Tj ET Q q 0 0 0 rg BT 240.56 127.60 Td (both ) Tj ET Q q 0 0 0 rg BT 260.09 127.60 Td (periods ) Tj ET Q q 0 0 0 rg BT 291.28 127.60 Td (due ) Tj ET Q q 0 0 0 rg BT 307.48 127.60 Td (to ) Tj ET Q q 0 0 0 rg BT 317.01 127.60 Td (lower ) Tj ET Q q 0 0 0 rg BT 341.53 127.60 Td (demand ) Tj ET Q q 0 0 0 rg BT 374.94 127.60 Td (resulting ) Tj ET Q q 0 0 0 rg BT 411.69 127.60 Td (from ) Tj ET Q q 0 0 0 rg BT 432.88 127.60 Td (increased ) Tj ET Q q 0 0 0 rg BT 472.39 127.60 Td (competition. ) Tj ET Q q 0 0 0 rg BT 524.29 127.60 Td (The ) Tj ET Q q 0 0 0 rg BT 541.59 127.60 Td (decrease ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 115.60 Td (in ) Tj ET Q q 0 0 0 rg BT 64.28 115.60 Td (2016 ) Tj ET Q q 0 0 0 rg BT 86.78 115.60 Td (was ) Tj ET Q q 0 0 0 rg BT 104.83 115.60 Td (also ) Tj ET Q q 0 0 0 rg BT 123.44 115.60 Td (impacted ) Tj ET Q q 0 0 0 rg BT 162.59 115.60 Td (by ) Tj ET Q q 0 0 0 rg BT 175.09 115.60 Td (unfavorable ) Tj ET Q q 0 0 0 rg BT 225.34 115.60 Td (foreign ) Tj ET Q q 0 0 0 rg BT 256.72 115.60 Td (exchange.) Tj ET Q endstream endobj 75 0 obj <> endobj 76 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Hepatitis ) Tj ET Q q 0 0 0 rg BT 75.43 749.10 Td (C ) Tj ET Q q 0 0 0 rg BT 85.42 749.10 Td (Franchise ) Tj ET Q q 0 0 0 rg BT 127.63 749.10 Td (— ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 140.13 749.10 Td (Daklinza ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 179.56 749.10 Td (\(daclatasvir\) ) Tj ET Q q 0 0 0 rg BT 232.86 749.10 Td (- ) Tj ET Q q 0 0 0 rg BT 239.51 749.10 Td (an ) Tj ET Q q 0 0 0 rg BT 252.27 749.10 Td (NS5A) Tj ET Q q 0 0 0 rg BT 276.73 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 280.05 749.10 Td (replication ) Tj ET Q q 0 0 0 rg BT 326.14 749.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 363.90 749.10 Td (inhibitor; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 404.44 749.10 Td (Sunvepra ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.54 749.10 Td (\(asunaprevir\) ) Tj ET Q q 0 0 0 rg BT 502.17 749.10 Td (- ) Tj ET Q q 0 0 0 rg BT 508.82 749.10 Td (an ) Tj ET Q q 0 0 0 rg BT 521.59 749.10 Td (NS3 ) Tj ET Q q 0 0 0 rg BT 542.69 749.10 Td (protease ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (inhibitor; ) Tj ET Q q 0 0 0 rg BT 75.72 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 92.66 737.10 Td (beclabuvir ) Tj ET Q q 0 0 0 rg BT 137.36 737.10 Td (- ) Tj ET Q q 0 0 0 rg BT 143.19 737.10 Td (an ) Tj ET Q q 0 0 0 rg BT 155.13 737.10 Td (NS5B ) Tj ET Q q 0 0 0 rg BT 182.08 737.10 Td (inhibitor) Tj ET Q q 0 0 0 rg BT 215.98 737.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 721.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 721.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.18 721.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.12 721.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 153.93 721.10 Td (in ) Tj ET Q q 0 0 0 rg BT 164.11 721.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 186.51 721.10 Td (due ) Tj ET Q q 0 0 0 rg BT 203.35 721.10 Td (to ) Tj ET Q q 0 0 0 rg BT 213.53 721.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 238.70 721.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 272.75 721.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 310.15 721.10 Td (from ) Tj ET Q q 0 0 0 rg BT 331.99 721.10 Td (new ) Tj ET Q q 0 0 0 rg BT 351.05 721.10 Td (product ) Tj ET Q q 0 0 0 rg BT 383.99 721.10 Td (entrants. ) Tj ET Q q 0 0 0 rg BT 420.55 721.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 440.73 721.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 478.67 721.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 518.82 721.10 Td (in ) Tj ET Q q 0 0 0 rg BT 529.00 721.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 551.40 721.10 Td (due ) Tj ET Q q 0 0 0 rg BT 568.24 721.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 709.10 Td (the ) Tj ET Q q 0 0 0 rg BT 68.72 709.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 97.87 709.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 108.70 709.10 Td (Daklinza ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 147.31 709.10 Td (in ) Tj ET Q q 0 0 0 rg BT 157.59 709.10 Td (July ) Tj ET Q q 0 0 0 rg BT 176.76 709.10 Td (2015.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 693.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 693.10 Td (International ) Tj ET Q q 0 0 0 rg BT 108.32 693.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 147.09 693.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 189.74 693.10 Td (in ) Tj ET Q q 0 0 0 rg BT 200.75 693.10 Td (both ) Tj ET Q q 0 0 0 rg BT 221.76 693.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 254.43 693.10 Td (due ) Tj ET Q q 0 0 0 rg BT 272.10 693.10 Td (to ) Tj ET Q q 0 0 0 rg BT 283.11 693.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 309.11 693.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 344.00 693.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 382.23 693.10 Td (from ) Tj ET Q q 0 0 0 rg BT 404.90 693.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 445.88 693.10 Td (competition ) Tj ET Q q 0 0 0 rg BT 496.89 693.10 Td (due ) Tj ET Q q 0 0 0 rg BT 514.56 693.10 Td (to ) Tj ET Q q 0 0 0 rg BT 525.57 693.10 Td (new ) Tj ET Q q 0 0 0 rg BT 545.46 693.10 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 681.10 Td (entrants.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 661.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 60.59 661.10 Td (Brands ) Tj ET Q q 0 0 0 rg BT 90.75 661.10 Td (— ) Tj ET Q q 0 0 0 rg BT 102.58 661.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 137.73 661.10 Td (all ) Tj ET Q q 0 0 0 rg BT 149.55 661.10 Td (other ) Tj ET Q q 0 0 0 rg BT 171.92 661.10 Td (brands, ) Tj ET Q q 0 0 0 rg BT 202.91 661.10 Td (including ) Tj ET Q q 0 0 0 rg BT 242.51 661.10 Td (those ) Tj ET Q q 0 0 0 rg BT 265.44 661.10 Td (which ) Tj ET Q q 0 0 0 rg BT 291.71 661.10 Td (have ) Tj ET Q q 0 0 0 rg BT 312.41 661.10 Td (lost ) Tj ET Q q 0 0 0 rg BT 328.69 661.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 374.39 661.10 Td (in ) Tj ET Q q 0 0 0 rg BT 384.00 661.10 Td (major ) Tj ET Q q 0 0 0 rg BT 409.15 661.10 Td (markets, ) Tj ET Q q 0 0 0 rg BT 445.13 661.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 466.96 661.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 495.44 661.10 Td (and ) Tj ET Q q 0 0 0 rg BT 511.71 661.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 541.86 661.10 Td (revenue.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 646.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 646.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.24 646.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 112.24 646.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 154.12 646.10 Td (in ) Tj ET Q q 0 0 0 rg BT 164.36 646.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 186.82 646.10 Td (due ) Tj ET Q q 0 0 0 rg BT 203.72 646.10 Td (to ) Tj ET Q q 0 0 0 rg BT 213.96 646.10 Td (the ) Tj ET Q q 0 0 0 rg BT 228.63 646.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 271.64 646.10 Td (of ) Tj ET Q q 0 0 0 rg BT 282.43 646.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 311.71 646.10 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 388.58 646.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 413.81 646.10 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 424.05 646.10 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.71 646.10 Td ( ) Tj ET Q q 0 0 0 rg BT 458.17 646.10 Td (in ) Tj ET Q q 0 0 0 rg BT 467.87 646.10 Td (April ) Tj ET Q q 0 0 0 rg BT 491.44 646.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 513.90 646.10 Td (and ) Tj ET Q q 0 0 0 rg BT 530.80 646.10 Td (the ) Tj ET Q q 0 0 0 rg BT 545.48 646.10 Td (transfer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 634.10 Td (of ) Tj ET Q q 0 0 0 rg BT 64.77 634.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 94.02 634.10 Td (North ) Tj ET Q q 0 0 0 rg BT 119.25 634.10 Td (American ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 161.10 634.10 Td (Erbitux* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 198.54 634.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 223.75 634.10 Td (to ) Tj ET Q q 0 0 0 rg BT 233.96 634.10 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 255.84 634.10 Td (in ) Tj ET Q q 0 0 0 rg BT 266.06 634.10 Td (October ) Tj ET Q q 0 0 0 rg BT 300.70 634.10 Td (2015. ) Tj ET Q q 0 0 0 rg BT 325.63 634.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 350.28 634.10 Td (to ) Tj ET Q q 0 0 0 rg BT 360.49 634.10 Td ("Item ) Tj ET Q q 0 0 0 rg BT 385.33 634.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 395.27 634.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 434.92 634.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.67 634.10 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.67 634.10 Td (. ) Tj ET Q q 0 0 0 rg BT 520.07 634.10 Td (Alliances" ) Tj ET Q q 0 0 0 rg BT 564.35 634.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 622.10 Td (further ) Tj ET Q q 0 0 0 rg BT 83.71 622.10 Td (discussion.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 607.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 607.10 Td (International ) Tj ET Q q 0 0 0 rg BT 107.39 607.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 145.23 607.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 186.95 607.10 Td (in ) Tj ET Q q 0 0 0 rg BT 197.03 607.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 219.33 607.10 Td (due ) Tj ET Q q 0 0 0 rg BT 236.07 607.10 Td (to ) Tj ET Q q 0 0 0 rg BT 246.15 607.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 300.67 607.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.41 607.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 361.92 607.10 Td (of ) Tj ET Q q 0 0 0 rg BT 372.55 607.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 402.06 607.10 Td (other ) Tj ET Q q 0 0 0 rg BT 424.91 607.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 453.87 607.10 Td (and ) Tj ET Q q 0 0 0 rg BT 470.61 607.10 Td (continued ) Tj ET Q q 0 0 0 rg BT 512.34 607.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 544.07 607.10 Td (erosion. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 595.10 Td (International ) Tj ET Q q 0 0 0 rg BT 107.86 595.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 146.18 595.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 188.37 595.10 Td (in ) Tj ET Q q 0 0 0 rg BT 198.92 595.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 221.70 595.10 Td (due ) Tj ET Q q 0 0 0 rg BT 238.91 595.10 Td (to ) Tj ET Q q 0 0 0 rg BT 249.47 595.10 Td (the ) Tj ET Q q 0 0 0 rg BT 264.46 595.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 307.78 595.10 Td (of ) Tj ET Q q 0 0 0 rg BT 318.88 595.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 348.86 595.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 378.31 595.10 Td (arrangements, ) Tj ET Q q 0 0 0 rg BT 437.44 595.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 482.43 595.10 Td (of ) Tj ET Q q 0 0 0 rg BT 493.54 595.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 523.52 595.10 Td (other ) Tj ET Q q 0 0 0 rg BT 546.84 595.10 Td (brands, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 583.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 94.25 583.10 Td (competition ) Tj ET Q q 0 0 0 rg BT 144.52 583.10 Td (for ) Tj ET Q q 0 0 0 rg BT 158.68 583.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 181.18 583.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 210.34 583.10 Td (and ) Tj ET Q q 0 0 0 rg BT 227.28 583.10 Td (unfavorable ) Tj ET Q q 0 0 0 rg BT 277.54 583.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 308.91 583.10 Td (exchange.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 559.10 Td (Estimated End-User Demand) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 541.10 Td (Pursuant ) Tj ET Q q 0 0 0 rg BT 74.09 541.10 Td (to ) Tj ET Q q 0 0 0 rg BT 84.95 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.26 541.10 Td (SEC ) Tj ET Q q 0 0 0 rg BT 121.68 541.10 Td (Consent ) Tj ET Q q 0 0 0 rg BT 157.55 541.10 Td (Order ) Tj ET Q q 0 0 0 rg BT 183.96 541.10 Td (described ) Tj ET Q q 0 0 0 rg BT 225.36 541.10 Td (under ) Tj ET Q q 0 0 0 rg BT 251.22 541.10 Td (“—SEC ) Tj ET Q q 0 0 0 rg BT 287.08 541.10 Td (Consent ) Tj ET Q q 0 0 0 rg BT 322.95 541.10 Td (Order”, ) Tj ET Q q 0 0 0 rg BT 356.29 541.10 Td (we ) Tj ET Q q 0 0 0 rg BT 371.04 541.10 Td (monitor ) Tj ET Q q 0 0 0 rg BT 405.79 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 421.10 541.10 Td (level ) Tj ET Q q 0 0 0 rg BT 443.62 541.10 Td (of ) Tj ET Q q 0 0 0 rg BT 455.04 541.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 496.45 541.10 Td (on ) Tj ET Q q 0 0 0 rg BT 509.54 541.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 532.06 541.10 Td (in ) Tj ET Q q 0 0 0 rg BT 542.93 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 558.23 541.10 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 529.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 81.52 529.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 129.84 529.10 Td (channel ) Tj ET Q q 0 0 0 rg BT 163.14 529.10 Td (and ) Tj ET Q q 0 0 0 rg BT 179.79 529.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 210.88 529.10 Td (of ) Tj ET Q q 0 0 0 rg BT 221.42 529.10 Td (the ) Tj ET Q q 0 0 0 rg BT 235.84 529.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 255.83 529.10 Td (in ) Tj ET Q q 0 0 0 rg BT 265.82 529.10 Td (the ) Tj ET Q q 0 0 0 rg BT 280.24 529.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 305.21 529.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 344.08 529.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 392.40 529.10 Td (channel. ) Tj ET Q q 0 0 0 rg BT 428.04 529.10 Td (W) Tj ET Q q 0 0 0 rg BT 436.68 529.10 Td (e ) Tj ET Q q 0 0 0 rg BT 443.32 529.10 Td (are ) Tj ET Q q 0 0 0 rg BT 457.73 529.10 Td (obligated ) Tj ET Q q 0 0 0 rg BT 497.15 529.10 Td (to ) Tj ET Q q 0 0 0 rg BT 507.14 529.10 Td (disclose ) Tj ET Q q 0 0 0 rg BT 541.56 529.10 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 517.10 Td (with ) Tj ET Q q 0 0 0 rg BT 56.82 517.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 83.18 517.10 Td (of ) Tj ET Q q 0 0 0 rg BT 94.54 517.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 135.91 517.10 Td (in ) Tj ET Q q 0 0 0 rg BT 146.72 517.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 175.86 517.10 Td (of ) Tj ET Q q 0 0 0 rg BT 187.23 517.10 Td (one ) Tj ET Q q 0 0 0 rg BT 204.70 517.10 Td (month ) Tj ET Q q 0 0 0 rg BT 233.29 517.10 Td (on ) Tj ET Q q 0 0 0 rg BT 246.33 517.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 268.81 517.10 Td (or ) Tj ET Q q 0 0 0 rg BT 280.17 517.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 318.74 517.10 Td (demand, ) Tj ET Q q 0 0 0 rg BT 355.94 517.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 387.30 517.10 Td (to ) Tj ET Q q 0 0 0 rg BT 398.11 517.10 Td (a ) Tj ET Q q 0 0 0 rg BT 405.59 517.10 Td (de ) Tj ET Q q 0 0 0 rg BT 418.07 517.10 Td (minimis ) Tj ET Q q 0 0 0 rg BT 453.89 517.10 Td (exception. ) Tj ET Q q 0 0 0 rg BT 498.29 517.10 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 541.32 517.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 567.68 517.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 505.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 77.74 505.10 Td (in ) Tj ET Q q 0 0 0 rg BT 88.93 505.10 Td (the ) Tj ET Q q 0 0 0 rg BT 104.56 505.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 154.09 505.10 Td (channel ) Tj ET Q q 0 0 0 rg BT 188.60 505.10 Td (in ) Tj ET Q q 0 0 0 rg BT 199.79 505.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 229.31 505.10 Td (of ) Tj ET Q q 0 0 0 rg BT 241.05 505.10 Td (one ) Tj ET Q q 0 0 0 rg BT 258.90 505.10 Td (month ) Tj ET Q q 0 0 0 rg BT 287.88 505.10 Td (on ) Tj ET Q q 0 0 0 rg BT 301.29 505.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 324.14 505.10 Td (for ) Tj ET Q q 0 0 0 rg BT 339.22 505.10 Td (the ) Tj ET Q q 0 0 0 rg BT 354.85 505.10 Td (following ) Tj ET Q q 0 0 0 rg BT 397.15 505.10 Td (products ) Tj ET Q q 0 0 0 rg BT 435.00 505.10 Td (were ) Tj ET Q q 0 0 0 rg BT 457.85 505.10 Td (not ) Tj ET Q q 0 0 0 rg BT 474.04 505.10 Td (material ) Tj ET Q q 0 0 0 rg BT 510.21 505.10 Td (to ) Tj ET Q q 0 0 0 rg BT 521.41 505.10 Td (our ) Tj ET Q q 0 0 0 rg BT 538.15 505.10 Td (results ) Tj ET Q q 0 0 0 rg BT 567.67 505.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 493.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 80.77 493.10 Td (as ) Tj ET Q q 0 0 0 rg BT 92.21 493.10 Td (of ) Tj ET Q q 0 0 0 rg BT 103.65 493.10 Td (the ) Tj ET Q q 0 0 0 rg BT 118.98 493.10 Td (dates ) Tj ET Q q 0 0 0 rg BT 142.64 493.10 Td (indicated. ) Tj ET Q q 0 0 0 rg BT 184.22 493.10 Td (At ) Tj ET Q q 0 0 0 rg BT 197.33 493.10 Td (December ) Tj ET Q q 0 0 0 rg BT 241.53 493.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 257.14 493.10 Td (2017, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 282.75 493.10 Td (Daklinza ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.98 493.10 Td (had ) Tj ET Q q 0 0 0 rg BT 339.53 493.10 Td (1.7 ) Tj ET Q q 0 0 0 rg BT 355.14 493.10 Td (months ) Tj ET Q q 0 0 0 rg BT 387.70 493.10 Td (of ) Tj ET Q q 0 0 0 rg BT 399.14 493.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 440.58 493.10 Td (on ) Tj ET Q q 0 0 0 rg BT 453.69 493.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 476.25 493.10 Td (in ) Tj ET Q q 0 0 0 rg BT 487.14 493.10 Td (the ) Tj ET Q q 0 0 0 rg BT 502.47 493.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 523.36 493.10 Td (as ) Tj ET Q q 0 0 0 rg BT 534.81 493.10 Td (a ) Tj ET Q q 0 0 0 rg BT 542.36 493.10 Td (result ) Tj ET Q q 0 0 0 rg BT 567.69 493.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 481.10 Td (minimum ) Tj ET Q q 0 0 0 rg BT 77.71 481.10 Td (required ) Tj ET Q q 0 0 0 rg BT 113.85 481.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 137.78 481.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 163.93 481.10 Td (to ) Tj ET Q q 0 0 0 rg BT 174.53 481.10 Td (support ) Tj ET Q q 0 0 0 rg BT 207.35 481.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 237.38 481.10 Td (demand. ) Tj ET Q q 0 0 0 rg BT 274.15 481.10 Td (W) Tj ET Q q 0 0 0 rg BT 282.79 481.10 Td (e ) Tj ET Q q 0 0 0 rg BT 290.05 481.10 Td (expect ) Tj ET Q q 0 0 0 rg BT 318.96 481.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 360.11 481.10 Td (on ) Tj ET Q q 0 0 0 rg BT 372.93 481.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 395.19 481.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 421.34 481.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 432.49 481.10 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 468.60 481.10 Td ( ) Tj ET Q q 0 0 0 rg BT 471.42 481.10 Td (to ) Tj ET Q q 0 0 0 rg BT 482.02 481.10 Td (exceed ) Tj ET Q q 0 0 0 rg BT 512.59 481.10 Td (one ) Tj ET Q q 0 0 0 rg BT 529.85 481.10 Td (month ) Tj ET Q q 0 0 0 rg BT 558.23 481.10 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 469.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.57 469.10 Td (near ) Tj ET Q q 0 0 0 rg BT 70.12 469.10 Td (term. ) Tj ET Q q 0 0 0 rg BT 93.29 469.10 Td (Below ) Tj ET Q q 0 0 0 rg BT 121.75 469.10 Td (are ) Tj ET Q q 0 0 0 rg BT 136.31 469.10 Td (international ) Tj ET Q q 0 0 0 rg BT 189.19 469.10 Td (products ) Tj ET Q q 0 0 0 rg BT 225.98 469.10 Td (that ) Tj ET Q q 0 0 0 rg BT 243.32 469.10 Td (had ) Tj ET Q q 0 0 0 rg BT 260.11 469.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 300.78 469.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 326.45 469.10 Td (of ) Tj ET Q q 0 0 0 rg BT 337.13 469.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 377.81 469.10 Td (in ) Tj ET Q q 0 0 0 rg BT 387.93 469.10 Td (the ) Tj ET Q q 0 0 0 rg BT 402.50 469.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 450.96 469.10 Td (channel ) Tj ET Q q 0 0 0 rg BT 484.40 469.10 Td (in ) Tj ET Q q 0 0 0 rg BT 494.53 469.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 522.98 469.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.66 469.10 Td (one ) Tj ET Q q 0 0 0 rg BT 550.44 469.10 Td (month ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 457.10 Td (on ) Tj ET Q q 0 0 0 rg BT 48.50 457.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 70.44 457.10 Td (at ) Tj ET Q q 0 0 0 rg BT 80.16 457.10 Td (September ) Tj ET Q q 0 0 0 rg BT 125.42 457.10 Td (30, ) Tj ET Q q 0 0 0 rg BT 140.42 457.10 Td (2017.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 72.00 438.10 Td (Dafalgan) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 109.78 438.10 Td (, ) Tj ET Q q 0 0 0 rg BT 113.73 438.10 Td (an ) Tj ET Q q 0 0 0 rg BT 124.62 438.10 Td (analgesic ) Tj ET Q q 0 0 0 rg BT 163.27 438.10 Td (product ) Tj ET Q q 0 0 0 rg BT 195.26 438.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 213.38 438.10 Td (principally ) Tj ET Q q 0 0 0 rg BT 258.15 438.10 Td (in ) Tj ET Q q 0 0 0 rg BT 267.38 438.10 Td (Europe, ) Tj ET Q q 0 0 0 rg BT 300.21 438.10 Td (had ) Tj ET Q q 0 0 0 rg BT 316.09 438.10 Td (1.2 ) Tj ET Q q 0 0 0 rg BT 330.04 438.10 Td (months ) Tj ET Q q 0 0 0 rg BT 360.94 438.10 Td (of ) Tj ET Q q 0 0 0 rg BT 370.72 438.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 410.49 438.10 Td (on ) Tj ET Q q 0 0 0 rg BT 421.94 438.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 442.83 438.10 Td (internationally ) Tj ET Q q 0 0 0 rg BT 502.59 438.10 Td (at ) Tj ET Q q 0 0 0 rg BT 511.26 438.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 535.47 438.10 Td (customers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 426.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 113.94 426.10 Td (to ) Tj ET Q q 0 0 0 rg BT 124.24 426.10 Td (also ) Tj ET Q q 0 0 0 rg BT 142.87 426.10 Td (1.2 ) Tj ET Q q 0 0 0 rg BT 157.89 426.10 Td (months ) Tj ET Q q 0 0 0 rg BT 189.86 426.10 Td (of ) Tj ET Q q 0 0 0 rg BT 200.71 426.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 241.55 426.10 Td (on ) Tj ET Q q 0 0 0 rg BT 254.07 426.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 276.03 426.10 Td (at ) Tj ET Q q 0 0 0 rg BT 285.76 426.10 Td (June ) Tj ET Q q 0 0 0 rg BT 306.61 426.10 Td (30, ) Tj ET Q q 0 0 0 rg BT 321.63 426.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 346.47 426.10 Td (The ) Tj ET Q q 0 0 0 rg BT 364.54 426.10 Td (level ) Tj ET Q q 0 0 0 rg BT 386.49 426.10 Td (of ) Tj ET Q q 0 0 0 rg BT 397.34 426.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 438.19 426.10 Td (on ) Tj ET Q q 0 0 0 rg BT 450.70 426.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 472.66 426.10 Td (was ) Tj ET Q q 0 0 0 rg BT 490.73 426.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 530.47 426.10 Td (attributable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 414.10 Td (to ) Tj ET Q q 0 0 0 rg BT 82.28 414.10 Td (France ) Tj ET Q q 0 0 0 rg BT 111.99 414.10 Td (to ) Tj ET Q q 0 0 0 rg BT 122.26 414.10 Td (support ) Tj ET Q q 0 0 0 rg BT 154.76 414.10 Td (product ) Tj ET Q q 0 0 0 rg BT 187.81 414.10 Td (seasonality) Tj ET Q q 0 0 0 rg BT 231.59 414.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 72.00 395.10 Td (Efferalgan) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 114.77 395.10 Td (, ) Tj ET Q q 0 0 0 rg BT 120.90 395.10 Td (an ) Tj ET Q q 0 0 0 rg BT 133.96 395.10 Td (analgesic ) Tj ET Q q 0 0 0 rg BT 174.79 395.10 Td (product ) Tj ET Q q 0 0 0 rg BT 208.96 395.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 229.25 395.10 Td (principally ) Tj ET Q q 0 0 0 rg BT 276.20 395.10 Td (in ) Tj ET Q q 0 0 0 rg BT 287.60 395.10 Td (Europe, ) Tj ET Q q 0 0 0 rg BT 322.60 395.10 Td (had ) Tj ET Q q 0 0 0 rg BT 340.67 395.10 Td (1.2 ) Tj ET Q q 0 0 0 rg BT 356.79 395.10 Td (months ) Tj ET Q q 0 0 0 rg BT 389.86 395.10 Td (of ) Tj ET Q q 0 0 0 rg BT 401.82 395.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 443.77 395.10 Td (on ) Tj ET Q q 0 0 0 rg BT 457.39 395.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 480.45 395.10 Td (internationally ) Tj ET Q q 0 0 0 rg BT 542.39 395.10 Td (at ) Tj ET Q q 0 0 0 rg BT 553.24 395.10 Td (direct ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 383.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 113.90 383.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 154.68 383.10 Td (to ) Tj ET Q q 0 0 0 rg BT 163.81 383.10 Td (0.8 ) Tj ET Q q 0 0 0 rg BT 177.66 383.10 Td (months ) Tj ET Q q 0 0 0 rg BT 208.46 383.10 Td (of ) Tj ET Q q 0 0 0 rg BT 218.14 383.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 257.82 383.10 Td (on ) Tj ET Q q 0 0 0 rg BT 269.17 383.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 289.96 383.10 Td (at ) Tj ET Q q 0 0 0 rg BT 298.53 383.10 Td (June ) Tj ET Q q 0 0 0 rg BT 318.22 383.10 Td (30, ) Tj ET Q q 0 0 0 rg BT 332.07 383.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 355.82 383.10 Td (The ) Tj ET Q q 0 0 0 rg BT 372.72 383.10 Td (level ) Tj ET Q q 0 0 0 rg BT 393.51 383.10 Td (of ) Tj ET Q q 0 0 0 rg BT 403.19 383.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 442.87 383.10 Td (on ) Tj ET Q q 0 0 0 rg BT 454.22 383.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 475.01 383.10 Td (was ) Tj ET Q q 0 0 0 rg BT 491.92 383.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 530.48 383.10 Td (attributable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 371.10 Td (to ) Tj ET Q q 0 0 0 rg BT 82.28 371.10 Td (France ) Tj ET Q q 0 0 0 rg BT 111.99 371.10 Td (to ) Tj ET Q q 0 0 0 rg BT 122.26 371.10 Td (support ) Tj ET Q q 0 0 0 rg BT 154.76 371.10 Td (product ) Tj ET Q q 0 0 0 rg BT 187.81 371.10 Td (seasonality) Tj ET Q q 0 0 0 rg BT 231.59 371.10 Td (. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 72.00 352.10 Td (Fervex) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 99.75 352.10 Td (, ) Tj ET Q q 0 0 0 rg BT 104.86 352.10 Td (a ) Tj ET Q q 0 0 0 rg BT 111.90 352.10 Td (cold ) Tj ET Q q 0 0 0 rg BT 131.72 352.10 Td (and ) Tj ET Q q 0 0 0 rg BT 148.76 352.10 Td (flu ) Tj ET Q q 0 0 0 rg BT 162.48 352.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 198.13 352.10 Td (had ) Tj ET Q q 0 0 0 rg BT 215.17 352.10 Td (3.0 ) Tj ET Q q 0 0 0 rg BT 230.27 352.10 Td (months ) Tj ET Q q 0 0 0 rg BT 262.33 352.10 Td (of ) Tj ET Q q 0 0 0 rg BT 273.26 352.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 314.19 352.10 Td (on ) Tj ET Q q 0 0 0 rg BT 326.79 352.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 348.84 352.10 Td (at ) Tj ET Q q 0 0 0 rg BT 358.66 352.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 384.02 352.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 427.17 352.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 469.20 352.10 Td (to ) Tj ET Q q 0 0 0 rg BT 479.58 352.10 Td (4.0 ) Tj ET Q q 0 0 0 rg BT 494.69 352.10 Td (months ) Tj ET Q q 0 0 0 rg BT 526.74 352.10 Td (of ) Tj ET Q q 0 0 0 rg BT 537.68 352.10 Td (inventory ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 340.10 Td (on ) Tj ET Q q 0 0 0 rg BT 84.50 340.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 106.44 340.10 Td (at ) Tj ET Q q 0 0 0 rg BT 116.16 340.10 Td (June ) Tj ET Q q 0 0 0 rg BT 136.99 340.10 Td (30, ) Tj ET Q q 0 0 0 rg BT 151.99 340.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 176.80 340.10 Td (The ) Tj ET Q q 0 0 0 rg BT 194.85 340.10 Td (level ) Tj ET Q q 0 0 0 rg BT 216.79 340.10 Td (of ) Tj ET Q q 0 0 0 rg BT 227.62 340.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 268.44 340.10 Td (on ) Tj ET Q q 0 0 0 rg BT 280.94 340.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 302.88 340.10 Td (was ) Tj ET Q q 0 0 0 rg BT 320.93 340.10 Td (attributable ) Tj ET Q q 0 0 0 rg BT 368.97 340.10 Td (to ) Tj ET Q q 0 0 0 rg BT 379.25 340.10 Td (France ) Tj ET Q q 0 0 0 rg BT 408.95 340.10 Td (to ) Tj ET Q q 0 0 0 rg BT 419.23 340.10 Td (support ) Tj ET Q q 0 0 0 rg BT 451.73 340.10 Td (product ) Tj ET Q q 0 0 0 rg BT 484.78 340.10 Td (seasonality) Tj ET Q q 0 0 0 rg BT 528.56 340.10 Td (. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 72.00 321.10 Td (Perfalgan) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 112.00 321.10 Td (, ) Tj ET Q q 0 0 0 rg BT 116.24 321.10 Td (an ) Tj ET Q q 0 0 0 rg BT 127.42 321.10 Td (analgesic ) Tj ET Q q 0 0 0 rg BT 166.36 321.10 Td (product, ) Tj ET Q q 0 0 0 rg BT 201.15 321.10 Td (had ) Tj ET Q q 0 0 0 rg BT 217.33 321.10 Td (2.6 ) Tj ET Q q 0 0 0 rg BT 231.57 321.10 Td (months ) Tj ET Q q 0 0 0 rg BT 262.76 321.10 Td (of ) Tj ET Q q 0 0 0 rg BT 272.84 321.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 312.90 321.10 Td (on ) Tj ET Q q 0 0 0 rg BT 324.65 321.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 345.83 321.10 Td (internationally ) Tj ET Q q 0 0 0 rg BT 405.88 321.10 Td (at ) Tj ET Q q 0 0 0 rg BT 414.84 321.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 439.35 321.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 481.64 321.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 522.80 321.10 Td (to ) Tj ET Q q 0 0 0 rg BT 532.33 321.10 Td (1.5 ) Tj ET Q q 0 0 0 rg BT 546.57 321.10 Td (months ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 309.10 Td (of ) Tj ET Q q 0 0 0 rg BT 83.43 309.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 124.86 309.10 Td (on ) Tj ET Q q 0 0 0 rg BT 137.96 309.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 160.50 309.10 Td (at ) Tj ET Q q 0 0 0 rg BT 170.82 309.10 Td (June ) Tj ET Q q 0 0 0 rg BT 192.25 309.10 Td (30, ) Tj ET Q q 0 0 0 rg BT 207.85 309.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 233.23 309.10 Td (The ) Tj ET Q q 0 0 0 rg BT 251.88 309.10 Td (level ) Tj ET Q q 0 0 0 rg BT 274.42 309.10 Td (of ) Tj ET Q q 0 0 0 rg BT 285.85 309.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 327.28 309.10 Td (on ) Tj ET Q q 0 0 0 rg BT 340.38 309.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 362.92 309.10 Td (was ) Tj ET Q q 0 0 0 rg BT 381.57 309.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 421.89 309.10 Td (in ) Tj ET Q q 0 0 0 rg BT 432.77 309.10 Td (the ) Tj ET Q q 0 0 0 rg BT 448.09 309.10 Td (Gulf ) Tj ET Q q 0 0 0 rg BT 469.52 309.10 Td (Countries ) Tj ET Q q 0 0 0 rg BT 511.51 309.10 Td (due ) Tj ET Q q 0 0 0 rg BT 529.05 309.10 Td (to ) Tj ET Q q 0 0 0 rg BT 539.93 309.10 Td (extended ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 297.10 Td (delivery ) Tj ET Q q 0 0 0 rg BT 107.26 297.10 Td (lead ) Tj ET Q q 0 0 0 rg BT 126.42 297.10 Td (time. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 278.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.43 278.10 Td (the ) Tj ET Q q 0 0 0 rg BT 62.75 278.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 86.13 278.10 Td (we ) Tj ET Q q 0 0 0 rg BT 100.89 278.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 141.19 278.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 184.27 278.10 Td (our ) Tj ET Q q 0 0 0 rg BT 200.70 278.10 Td (months ) Tj ET Q q 0 0 0 rg BT 233.25 278.10 Td (on ) Tj ET Q q 0 0 0 rg BT 246.35 278.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 268.89 278.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 309.20 278.10 Td (using ) Tj ET Q q 0 0 0 rg BT 333.97 278.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 375.39 278.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 401.82 278.10 Td (of ) Tj ET Q q 0 0 0 rg BT 413.25 278.10 Td (product ) Tj ET Q q 0 0 0 rg BT 446.89 278.10 Td (on ) Tj ET Q q 0 0 0 rg BT 459.99 278.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 482.53 278.10 Td (and ) Tj ET Q q 0 0 0 rg BT 500.07 278.10 Td (the ) Tj ET Q q 0 0 0 rg BT 515.38 278.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 548.48 278.10 Td (of ) Tj ET Q q 0 0 0 rg BT 559.91 278.10 Td (out-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 266.10 Td (movement ) Tj ET Q q 0 0 0 rg BT 80.33 266.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 118.00 266.10 Td (by ) Tj ET Q q 0 0 0 rg BT 130.13 266.10 Td (our ) Tj ET Q q 0 0 0 rg BT 145.58 266.10 Td (three ) Tj ET Q q 0 0 0 rg BT 167.69 266.10 Td (lar) Tj ET Q q 0 0 0 rg BT 178.06 266.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 196.29 266.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 248.12 266.10 Td (which ) Tj ET Q q 0 0 0 rg BT 274.68 266.10 Td (account ) Tj ET Q q 0 0 0 rg BT 307.90 266.10 Td (for ) Tj ET Q q 0 0 0 rg BT 321.68 266.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 381.56 266.10 Td (95% ) Tj ET Q q 0 0 0 rg BT 402.01 266.10 Td (of ) Tj ET Q q 0 0 0 rg BT 412.47 266.10 Td (total ) Tj ET Q q 0 0 0 rg BT 432.36 266.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 455.60 266.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 477.16 266.10 Td (of ) Tj ET Q q 0 0 0 rg BT 487.61 266.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 507.52 266.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 546.58 266.10 Td (Factors ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 254.10 Td (that ) Tj ET Q q 0 0 0 rg BT 54.50 254.10 Td (may ) Tj ET Q q 0 0 0 rg BT 75.22 254.10 Td (influence ) Tj ET Q q 0 0 0 rg BT 115.93 254.10 Td (our ) Tj ET Q q 0 0 0 rg BT 132.77 254.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 173.49 254.10 Td (include ) Tj ET Q q 0 0 0 rg BT 206.42 254.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 239.35 254.10 Td (competition, ) Tj ET Q q 0 0 0 rg BT 293.13 254.10 Td (seasonality ) Tj ET Q q 0 0 0 rg BT 341.07 254.10 Td (of ) Tj ET Q q 0 0 0 rg BT 352.90 254.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 393.35 254.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 440.17 254.10 Td (purchases ) Tj ET Q q 0 0 0 rg BT 483.10 254.10 Td (in ) Tj ET Q q 0 0 0 rg BT 494.39 254.10 Td (light ) Tj ET Q q 0 0 0 rg BT 516.23 254.10 Td (of ) Tj ET Q q 0 0 0 rg BT 528.07 254.10 Td (increases ) Tj ET Q q 0 0 0 rg BT 568.22 254.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 242.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 82.09 242.10 Td (list ) Tj ET Q q 0 0 0 rg BT 97.08 242.10 Td (prices, ) Tj ET Q q 0 0 0 rg BT 126.23 242.10 Td (new ) Tj ET Q q 0 0 0 rg BT 145.66 242.10 Td (product ) Tj ET Q q 0 0 0 rg BT 178.98 242.10 Td (launches, ) Tj ET Q q 0 0 0 rg BT 219.23 242.10 Td (new ) Tj ET Q q 0 0 0 rg BT 238.66 242.10 Td (warehouse ) Tj ET Q q 0 0 0 rg BT 284.19 242.10 Td (openings ) Tj ET Q q 0 0 0 rg BT 323.07 242.10 Td (by ) Tj ET Q q 0 0 0 rg BT 335.84 242.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 385.82 242.10 Td (and ) Tj ET Q q 0 0 0 rg BT 403.02 242.10 Td (new ) Tj ET Q q 0 0 0 rg BT 422.45 242.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 461.88 242.10 Td (stockings ) Tj ET Q q 0 0 0 rg BT 502.43 242.10 Td (by ) Tj ET Q q 0 0 0 rg BT 515.20 242.10 Td (wholesalers. ) Tj ET Q q 0 0 0 rg BT 567.68 242.10 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 230.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 73.77 230.10 Td (these ) Tj ET Q q 0 0 0 rg BT 96.82 230.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 136.53 230.10 Td (are ) Tj ET Q q 0 0 0 rg BT 151.24 230.10 Td (calculated ) Tj ET Q q 0 0 0 rg BT 194.27 230.10 Td (using ) Tj ET Q q 0 0 0 rg BT 218.44 230.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 263.70 230.10 Td (data, ) Tj ET Q q 0 0 0 rg BT 285.36 230.10 Td (which ) Tj ET Q q 0 0 0 rg BT 312.29 230.10 Td (may ) Tj ET Q q 0 0 0 rg BT 332.01 230.10 Td (be ) Tj ET Q q 0 0 0 rg BT 343.95 230.10 Td (impacted ) Tj ET Q q 0 0 0 rg BT 383.10 230.10 Td (by ) Tj ET Q q 0 0 0 rg BT 395.60 230.10 Td (their ) Tj ET Q q 0 0 0 rg BT 416.42 230.10 Td (recordkeeping ) Tj ET Q q 0 0 0 rg BT 476.12 230.10 Td (processes.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 208.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.73 208.50 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 92.03 208.50 Td (businesses ) Tj ET Q q 0 0 0 rg BT 136.43 208.50 Td (have ) Tj ET Q q 0 0 0 rg BT 157.48 208.50 Td (significantly ) Tj ET Q q 0 0 0 rg BT 209.65 208.50 Td (more ) Tj ET Q q 0 0 0 rg BT 232.38 208.50 Td (direct ) Tj ET Q q 0 0 0 rg BT 257.33 208.50 Td (customers. ) Tj ET Q q 0 0 0 rg BT 302.55 208.50 Td (Information ) Tj ET Q q 0 0 0 rg BT 352.50 208.50 Td (on ) Tj ET Q q 0 0 0 rg BT 364.68 208.50 Td (available ) Tj ET Q q 0 0 0 rg BT 402.95 208.50 Td (direct ) Tj ET Q q 0 0 0 rg BT 427.89 208.50 Td (customer ) Tj ET Q q 0 0 0 rg BT 466.73 208.50 Td (product ) Tj ET Q q 0 0 0 rg BT 499.45 208.50 Td (level ) Tj ET Q q 0 0 0 rg BT 521.07 208.50 Td (inventory ) Tj ET Q q 0 0 0 rg BT 561.57 208.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 196.50 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 94.72 196.50 Td (out-movement ) Tj ET Q q 0 0 0 rg BT 154.55 196.50 Td (information ) Tj ET Q q 0 0 0 rg BT 203.28 196.50 Td (and ) Tj ET Q q 0 0 0 rg BT 219.23 196.50 Td (the ) Tj ET Q q 0 0 0 rg BT 232.96 196.50 Td (reliability ) Tj ET Q q 0 0 0 rg BT 273.35 196.50 Td (of ) Tj ET Q q 0 0 0 rg BT 283.20 196.50 Td (third-party ) Tj ET Q q 0 0 0 rg BT 327.47 196.50 Td (demand ) Tj ET Q q 0 0 0 rg BT 360.64 196.50 Td (information ) Tj ET Q q 0 0 0 rg BT 409.37 196.50 Td (varies ) Tj ET Q q 0 0 0 rg BT 434.76 196.50 Td (widely) Tj ET Q q 0 0 0 rg BT 461.33 196.50 Td (. ) Tj ET Q q 0 0 0 rg BT 465.23 196.50 Td (W) Tj ET Q q 0 0 0 rg BT 473.87 196.50 Td (e ) Tj ET Q q 0 0 0 rg BT 479.82 196.50 Td (limit ) Tj ET Q q 0 0 0 rg BT 500.23 196.50 Td (our ) Tj ET Q q 0 0 0 rg BT 515.07 196.50 Td (direct ) Tj ET Q q 0 0 0 rg BT 539.35 196.50 Td (customer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 184.50 Td (sales ) Tj ET Q q 0 0 0 rg BT 57.68 184.50 Td (channel ) Tj ET Q q 0 0 0 rg BT 91.01 184.50 Td (inventory ) Tj ET Q q 0 0 0 rg BT 131.57 184.50 Td (reporting ) Tj ET Q q 0 0 0 rg BT 170.47 184.50 Td (to ) Tj ET Q q 0 0 0 rg BT 180.48 184.50 Td (where ) Tj ET Q q 0 0 0 rg BT 207.15 184.50 Td (we ) Tj ET Q q 0 0 0 rg BT 221.05 184.50 Td (can ) Tj ET Q q 0 0 0 rg BT 237.17 184.50 Td (influence ) Tj ET Q q 0 0 0 rg BT 276.61 184.50 Td (demand. ) Tj ET Q q 0 0 0 rg BT 312.84 184.50 Td (When ) Tj ET Q q 0 0 0 rg BT 338.96 184.50 Td (this ) Tj ET Q q 0 0 0 rg BT 355.64 184.50 Td (information ) Tj ET Q q 0 0 0 rg BT 405.09 184.50 Td (does ) Tj ET Q q 0 0 0 rg BT 425.66 184.50 Td (not ) Tj ET Q q 0 0 0 rg BT 440.68 184.50 Td (exist ) Tj ET Q q 0 0 0 rg BT 461.81 184.50 Td (or ) Tj ET Q q 0 0 0 rg BT 472.37 184.50 Td (is ) Tj ET Q q 0 0 0 rg BT 481.28 184.50 Td (otherwise ) Tj ET Q q 0 0 0 rg BT 522.40 184.50 Td (not ) Tj ET Q q 0 0 0 rg BT 537.42 184.50 Td (available, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 172.50 Td (we ) Tj ET Q q 0 0 0 rg BT 49.90 172.50 Td (have ) Tj ET Q q 0 0 0 rg BT 71.02 172.50 Td (developed ) Tj ET Q q 0 0 0 rg BT 114.36 172.50 Td (a ) Tj ET Q q 0 0 0 rg BT 121.04 172.50 Td (variety ) Tj ET Q q 0 0 0 rg BT 151.05 172.50 Td (of ) Tj ET Q q 0 0 0 rg BT 161.63 172.50 Td (methodologies ) Tj ET Q q 0 0 0 rg BT 222.75 172.50 Td (to ) Tj ET Q q 0 0 0 rg BT 232.77 172.50 Td (estimate ) Tj ET Q q 0 0 0 rg BT 268.34 172.50 Td (such ) Tj ET Q q 0 0 0 rg BT 288.91 172.50 Td (data, ) Tj ET Q q 0 0 0 rg BT 310.31 172.50 Td (including ) Tj ET Q q 0 0 0 rg BT 350.33 172.50 Td (using ) Tj ET Q q 0 0 0 rg BT 374.24 172.50 Td (historical ) Tj ET Q q 0 0 0 rg BT 413.70 172.50 Td (sales ) Tj ET Q q 0 0 0 rg BT 435.38 172.50 Td (made ) Tj ET Q q 0 0 0 rg BT 459.28 172.50 Td (to ) Tj ET Q q 0 0 0 rg BT 469.30 172.50 Td (direct ) Tj ET Q q 0 0 0 rg BT 494.31 172.50 Td (customers ) Tj ET Q q 0 0 0 rg BT 537.10 172.50 Td (and ) Tj ET Q q 0 0 0 rg BT 553.78 172.50 Td (third-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 160.50 Td (party ) Tj ET Q q 0 0 0 rg BT 59.30 160.50 Td (market ) 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0 0 0 rg BT 504.93 88.50 Td (month ) Tj ET Q q 0 0 0 rg BT 533.08 88.50 Td (on ) Tj ET Q q 0 0 0 rg BT 545.67 88.50 Td (hand ) Tj ET Q q 0 0 0 rg BT 567.69 88.50 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 76.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 74.03 76.50 Td (demand, ) Tj ET Q q 0 0 0 rg BT 110.69 76.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 141.51 76.50 Td (to ) Tj ET Q q 0 0 0 rg BT 151.79 76.50 Td (a ) Tj ET Q q 0 0 0 rg BT 158.73 76.50 Td (de ) Tj ET Q q 0 0 0 rg BT 170.67 76.50 Td (minimis ) Tj ET Q q 0 0 0 rg BT 205.95 76.50 Td (exception, ) Tj ET Q q 0 0 0 rg BT 249.82 76.50 Td (in ) Tj ET Q q 0 0 0 rg BT 260.10 76.50 Td (the ) Tj ET Q q 0 0 0 rg BT 274.82 76.50 Td (next ) Tj ET Q q 0 0 0 rg BT 294.54 76.50 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 333.13 76.50 Td (report ) Tj ET Q q 0 0 0 rg BT 359.51 76.50 Td (on ) Tj ET Q q 0 0 0 rg BT 372.01 76.50 Td (Form ) Tj ET Q q 0 0 0 rg BT 396.18 76.50 Td (10-Q.) 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Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 454.90 709.98 Td (2017 vs. 2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 521.90 709.98 Td (2016 vs. 2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 696.37 Td (Cost of products sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.00 696.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.15 696.37 Td (6,066) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 329.00 696.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.15 696.37 Td (4,946) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.00 696.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.15 696.37 Td (3,909) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.30 696.37 Td (23) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.65 696.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 696.37 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 696.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 684.37 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.15 684.37 Td (4,687) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.15 684.37 Td (4,91) Tj ET Q q 0 0 0 rg BT 373.65 684.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.15 684.37 Td (4,841) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.95 684.37 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.30 684.37 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 684.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 684.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 672.37 Td (Research and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.15 672.37 Td (6,41) Tj ET Q q 0 0 0 rg BT 313.65 672.37 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.15 672.37 Td (4,940) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.15 672.37 Td (5,920) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.30 672.37 Td (30) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.65 672.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.95 672.37 Td (\(17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 672.37 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 660.37 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.80 660.37 Td (\(1,519) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.65 660.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.80 660.37 Td (\(1,285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.65 660.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.30 660.37 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.65 660.37 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.30 660.37 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.65 660.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.00 660.37 Td (**) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 648.37 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 648.37 Td (otal Expenses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.00 648.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 291.15 648.37 Td (15,645) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 329.00 648.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 351.15 648.37 Td (13,512) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.00 648.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.15 648.37 Td (14,483) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.30 648.37 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.65 648.37 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.95 648.37 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 648.37 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 631.65 Td (** ) Tj ET Q q 0 0 0 rg BT 58.50 631.65 Td (Change ) Tj ET Q q 0 0 0 rg BT 84.94 631.65 Td (in ) Tj ET Q q 0 0 0 rg BT 93.16 631.65 Td (excess ) Tj ET Q q 0 0 0 rg BT 116.04 631.65 Td (of ) Tj ET Q q 0 0 0 rg BT 124.70 631.65 Td (100%) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 611.1169921875 m 120.9169921875 611.1169921875 l s q 0 0 0 rg BT 36.00 612.45 Td (Cost of pr) Tj ET Q q 0 0 0 rg BT 75.64 612.45 Td (oducts sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 588.45 Td (Cost ) Tj ET Q q 0 0 0 rg BT 57.28 588.45 Td (of ) Tj ET Q q 0 0 0 rg BT 68.56 588.45 Td (products ) Tj ET Q q 0 0 0 rg BT 105.94 588.45 Td (sold ) Tj ET Q q 0 0 0 rg BT 125.55 588.45 Td (include ) Tj ET Q q 0 0 0 rg BT 157.93 588.45 Td (material, ) Tj ET Q q 0 0 0 rg BT 196.13 588.45 Td (internal ) Tj ET Q q 0 0 0 rg BT 229.62 588.45 Td (labor ) Tj ET Q q 0 0 0 rg BT 253.11 588.45 Td (and ) Tj ET Q q 0 0 0 rg BT 270.49 588.45 Td (overhead ) Tj ET Q q 0 0 0 rg BT 310.08 588.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 333.02 588.45 Td (from ) Tj ET Q q 0 0 0 rg BT 355.40 588.45 Td (our ) Tj ET Q q 0 0 0 rg BT 371.68 588.45 Td (owned ) Tj ET Q q 0 0 0 rg BT 401.28 588.45 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 462.53 588.45 Td (sites, ) Tj ET Q q 0 0 0 rg BT 485.75 588.45 Td (third-party ) Tj ET Q q 0 0 0 rg BT 531.46 588.45 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 576.45 Td (supply ) Tj ET Q q 0 0 0 rg BT 65.09 576.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 87.51 576.45 Td (and ) Tj ET Q q 0 0 0 rg BT 104.37 576.45 Td (other ) Tj ET Q q 0 0 0 rg BT 127.34 576.45 Td (supply ) Tj ET Q q 0 0 0 rg BT 156.43 576.45 Td (chain ) Tj ET Q q 0 0 0 rg BT 180.51 576.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 202.93 576.45 Td (managed ) Tj ET Q q 0 0 0 rg BT 241.44 576.45 Td (by ) Tj ET Q q 0 0 0 rg BT 253.86 576.45 Td (our ) Tj ET Q q 0 0 0 rg BT 269.61 576.45 Td (global ) Tj ET Q q 0 0 0 rg BT 297.03 576.45 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 357.76 576.45 Td (and ) Tj ET Q q 0 0 0 rg BT 374.62 576.45 Td (supply ) Tj ET Q q 0 0 0 rg BT 403.71 576.45 Td (or) Tj ET Q q 0 0 0 rg BT 411.86 576.45 Td (ganization. ) Tj ET Q q 0 0 0 rg BT 458.43 576.45 Td (Cost ) Tj ET Q q 0 0 0 rg BT 479.19 576.45 Td (of ) Tj ET Q q 0 0 0 rg BT 489.94 576.45 Td (products ) Tj ET Q q 0 0 0 rg BT 526.80 576.45 Td (sold ) Tj ET Q q 0 0 0 rg BT 545.89 576.45 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 564.45 Td (includes ) Tj ET Q q 0 0 0 rg BT 71.58 564.45 Td (royalties ) Tj ET Q q 0 0 0 rg BT 108.27 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 124.97 564.45 Td (profit ) Tj ET Q q 0 0 0 rg BT 149.44 564.45 Td (sharing, ) Tj ET Q q 0 0 0 rg BT 183.64 564.45 Td (certain ) Tj ET Q q 0 0 0 rg BT 213.10 564.45 Td (excise ) Tj ET Q q 0 0 0 rg BT 240.34 564.45 Td (taxes, ) Tj ET Q q 0 0 0 rg BT 265.65 564.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 296.78 564.45 Td (currency ) Tj ET Q q 0 0 0 rg BT 334.01 564.45 Td (hedge ) Tj ET Q q 0 0 0 rg BT 360.15 564.45 Td (settlement ) Tj ET Q q 0 0 0 rg BT 403.50 564.45 Td (gains ) Tj ET Q q 0 0 0 rg BT 426.87 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 443.56 564.45 Td (losses ) Tj ET Q q 0 0 0 rg BT 469.71 564.45 Td (and ) Tj ET Q q 0 0 0 rg BT 486.41 564.45 Td (the ) Tj ET Q q 0 0 0 rg BT 500.88 564.45 Td (amortization ) Tj ET Q q 0 0 0 rg BT 553.68 564.45 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 552.45 Td (acquired ) Tj ET Q q 0 0 0 rg BT 73.39 552.45 Td (developed ) Tj ET Q q 0 0 0 rg BT 117.46 552.45 Td (technology ) Tj ET Q q 0 0 0 rg BT 164.86 552.45 Td (costs. ) Tj ET Q q 0 0 0 rg BT 190.33 552.45 Td (Cost ) Tj ET Q q 0 0 0 rg BT 211.63 552.45 Td (of ) Tj ET Q q 0 0 0 rg BT 222.93 552.45 Td (products ) Tj ET Q q 0 0 0 rg BT 260.34 552.45 Td (sold ) Tj ET Q q 0 0 0 rg BT 279.98 552.45 Td (typically ) Tj ET Q q 0 0 0 rg BT 317.94 552.45 Td (vary ) Tj ET Q q 0 0 0 rg BT 338.68 552.45 Td (between ) Tj ET Q q 0 0 0 rg BT 374.96 552.45 Td (periods ) Tj ET Q q 0 0 0 rg BT 407.37 552.45 Td (as ) Tj ET Q q 0 0 0 rg BT 418.67 552.45 Td (a ) Tj ET Q q 0 0 0 rg BT 426.07 552.45 Td (result ) Tj ET Q q 0 0 0 rg BT 451.26 552.45 Td (of ) Tj ET Q q 0 0 0 rg BT 462.56 552.45 Td (product ) Tj ET Q q 0 0 0 rg BT 496.07 552.45 Td (mix ) Tj ET Q q 0 0 0 rg BT 514.60 552.45 Td (and ) Tj ET Q q 0 0 0 rg BT 532.01 552.45 Td (volume ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 540.45 Td (\(particularly ) Tj ET Q q 0 0 0 rg BT 88.25 540.45 Td (royalties ) Tj ET Q q 0 0 0 rg BT 125.51 540.45 Td (and ) Tj ET Q q 0 0 0 rg BT 142.78 540.45 Td (profit ) Tj ET Q q 0 0 0 rg BT 167.83 540.45 Td (sharing\), ) Tj ET Q q 0 0 0 rg BT 205.93 540.45 Td (and ) Tj ET Q q 0 0 0 rg BT 223.20 540.45 Td (to ) Tj ET Q q 0 0 0 rg BT 233.81 540.45 Td (a ) Tj ET Q q 0 0 0 rg BT 241.08 540.45 Td (lesser ) Tj ET Q q 0 0 0 rg BT 266.68 540.45 Td (extent ) Tj ET Q q 0 0 0 rg BT 293.94 540.45 Td (changes ) Tj ET Q q 0 0 0 rg BT 328.98 540.45 Td (in ) Tj ET Q q 0 0 0 rg BT 339.59 540.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 371.30 540.45 Td (currency) Tj ET Q q 0 0 0 rg BT 405.63 540.45 Td (, ) Tj ET Q q 0 0 0 rg BT 410.96 540.45 Td (price, ) Tj ET Q q 0 0 0 rg BT 436.27 540.45 Td (inflation ) Tj ET Q q 0 0 0 rg BT 472.99 540.45 Td (and ) Tj ET Q q 0 0 0 rg BT 490.26 540.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 513.09 540.45 Td (attributed ) Tj ET Q q 0 0 0 rg BT 554.24 540.45 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 528.45 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 96.81 528.45 Td (site ) Tj ET Q q 0 0 0 rg BT 113.20 528.45 Td (exits.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 510.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 510.45 Td (Cost ) Tj ET Q q 0 0 0 rg BT 82.61 510.45 Td (of ) Tj ET Q q 0 0 0 rg BT 93.87 510.45 Td (products ) Tj ET Q q 0 0 0 rg BT 131.23 510.45 Td (sold ) Tj ET Q q 0 0 0 rg BT 150.83 510.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 191.51 510.45 Td (in ) Tj ET Q q 0 0 0 rg BT 202.21 510.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 225.13 510.45 Td (due ) Tj ET Q q 0 0 0 rg BT 242.50 510.45 Td (to ) Tj ET Q q 0 0 0 rg BT 253.20 510.45 Td (higher ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 281.67 510.45 Td (Eliquis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.93 510.45 Td (profit ) Tj ET Q q 0 0 0 rg BT 338.07 510.45 Td (sharing ) Tj ET Q q 0 0 0 rg BT 370.44 510.45 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.69 510.45 Td ($719 ) Tj ET Q q 0 0 0 rg BT 404.62 510.45 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.51 510.45 Td ( ) Tj ET Q q 0 0 0 rg BT 436.43 510.45 Td (and ) Tj ET Q q 0 0 0 rg BT 453.80 510.45 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.16 510.45 Td ($146 ) Tj ET Q q 0 0 0 rg BT 484.08 510.45 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.98 510.45 Td ( ) Tj ET Q q 0 0 0 rg BT 515.90 510.45 Td (impairment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 498.45 Td (char) Tj ET Q q 0 0 0 rg BT 78.38 498.45 Td (ge ) Tj ET Q q 0 0 0 rg BT 89.56 498.45 Td (to ) Tj ET Q q 0 0 0 rg BT 99.09 498.45 Td (reduce ) Tj ET Q q 0 0 0 rg BT 127.48 498.45 Td (the ) Tj ET Q q 0 0 0 rg BT 141.45 498.45 Td (carrying ) Tj ET Q q 0 0 0 rg BT 176.51 498.45 Td (value ) Tj ET Q q 0 0 0 rg BT 199.91 498.45 Td (of ) Tj ET Q q 0 0 0 rg BT 209.99 498.45 Td (the ) Tj ET Q q 0 0 0 rg BT 223.96 498.45 Td (small ) Tj ET Q q 0 0 0 rg BT 247.37 498.45 Td (molecule ) Tj ET Q q 0 0 0 rg BT 285.77 498.45 Td (active ) Tj ET Q q 0 0 0 rg BT 311.39 498.45 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 374.21 498.45 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 416.50 498.45 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 476.56 498.45 Td (operations ) Tj ET Q q 0 0 0 rg BT 519.96 498.45 Td (in ) Tj ET Q q 0 0 0 rg BT 529.49 498.45 Td (Swords, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 486.45 Td (Ireland. ) Tj ET Q q 0 0 0 rg BT 94.34 486.45 Td (The ) Tj ET Q q 0 0 0 rg BT 112.24 486.45 Td (remaining ) Tj ET Q q 0 0 0 rg BT 155.12 486.45 Td (increase ) Tj ET Q q 0 0 0 rg BT 190.22 486.45 Td (was ) Tj ET Q q 0 0 0 rg BT 208.12 486.45 Td (primarily ) Tj ET Q q 0 0 0 rg BT 247.68 486.45 Td (due ) Tj ET Q q 0 0 0 rg BT 264.46 486.45 Td (to ) Tj ET Q q 0 0 0 rg BT 274.59 486.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 302.48 486.45 Td (sales ) Tj ET Q q 0 0 0 rg BT 324.27 486.45 Td (volume, ) Tj ET Q q 0 0 0 rg BT 359.11 486.45 Td (inventory ) Tj ET Q q 0 0 0 rg BT 399.78 486.45 Td (char) Tj ET Q q 0 0 0 rg BT 416.81 486.45 Td (ges, ) Tj ET Q q 0 0 0 rg BT 434.98 486.45 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 495.64 486.45 Td (startup ) Tj ET Q q 0 0 0 rg BT 525.20 486.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 547.55 486.45 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 474.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 92.39 474.45 Td (currency) Tj ET Q q 0 0 0 rg BT 126.72 474.45 Td (. ) Tj ET Q q 0 0 0 rg BT 131.39 474.45 Td (Refer ) Tj ET Q q 0 0 0 rg BT 155.76 474.45 Td (to ) Tj ET Q q 0 0 0 rg BT 165.71 474.45 Td ("Item ) Tj ET Q q 0 0 0 rg BT 190.28 474.45 Td (8. ) Tj ET Q q 0 0 0 rg BT 199.95 474.45 Td (Financial ) Tj ET Q q 0 0 0 rg BT 239.33 474.45 Td (Statements—Note ) Tj ET Q q 0 0 0 rg BT 314.81 474.45 Td (4. ) Tj ET Q q 0 0 0 rg BT 324.00 474.45 Td (Acquisitions, ) Tj ET Q q 0 0 0 rg BT 379.23 474.45 Td (Divestitures ) Tj ET Q q 0 0 0 rg BT 429.72 474.45 Td (and ) Tj ET Q q 0 0 0 rg BT 446.32 474.45 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 487.45 474.45 Td (Arrangements" ) Tj ET Q q 0 0 0 rg BT 550.34 474.45 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 462.45 Td (further ) Tj ET Q q 0 0 0 rg BT 91.06 462.45 Td (information. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 444.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 444.45 Td (Cost ) Tj ET Q q 0 0 0 rg BT 82.81 444.45 Td (of ) Tj ET Q q 0 0 0 rg BT 94.27 444.45 Td (products ) Tj ET Q q 0 0 0 rg BT 131.83 444.45 Td (sold ) Tj ET Q q 0 0 0 rg BT 151.62 444.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 192.50 444.45 Td (in ) Tj ET Q q 0 0 0 rg BT 203.40 444.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 226.53 444.45 Td (due ) Tj ET Q q 0 0 0 rg BT 244.09 444.45 Td (to ) Tj ET Q q 0 0 0 rg BT 254.99 444.45 Td (higher ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 283.66 444.45 Td (Eliquis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.12 444.45 Td (profit ) Tj ET Q q 0 0 0 rg BT 340.46 444.45 Td (sharing ) Tj ET Q q 0 0 0 rg BT 373.03 444.45 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.48 444.45 Td ($700 ) Tj ET Q q 0 0 0 rg BT 407.60 444.45 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.50 444.45 Td (, ) Tj ET Q q 0 0 0 rg BT 442.12 444.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 468.01 444.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 500.01 444.45 Td (currency ) Tj ET Q q 0 0 0 rg BT 538.11 444.45 Td (hedge ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 432.45 Td (settlement ) Tj ET Q q 0 0 0 rg BT 104.95 432.45 Td (gains ) Tj ET Q q 0 0 0 rg BT 128.56 432.45 Td (and ) Tj ET Q q 0 0 0 rg BT 145.50 432.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 173.54 432.45 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 202.15 432.45 Td (Rico ) Tj ET Q q 0 0 0 rg BT 223.54 432.45 Td (excise ) Tj ET Q q 0 0 0 rg BT 251.02 432.45 Td (tax.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 407.1169921875 m 187.09375 407.1169921875 l s q 0 0 0 rg BT 36.00 408.45 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 384.45 Td (Marketing, ) Tj ET Q q 0 0 0 rg BT 81.95 384.45 Td (selling ) Tj ET Q q 0 0 0 rg BT 110.42 384.45 Td (and ) Tj ET Q q 0 0 0 rg BT 126.66 384.45 Td (administrative ) Tj ET Q q 0 0 0 rg BT 185.66 384.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 223.56 384.45 Td (primarily ) Tj ET Q q 0 0 0 rg BT 262.57 384.45 Td (include ) Tj ET Q q 0 0 0 rg BT 293.81 384.45 Td (salary ) Tj ET Q q 0 0 0 rg BT 319.48 384.45 Td (and ) Tj ET Q q 0 0 0 rg BT 335.72 384.45 Td (benefit ) Tj ET Q q 0 0 0 rg BT 365.28 384.45 Td (costs, ) Tj ET Q q 0 0 0 rg BT 389.58 384.45 Td (third-party ) Tj ET Q q 0 0 0 rg BT 434.14 384.45 Td (professional ) Tj ET Q q 0 0 0 rg BT 484.82 384.45 Td (and ) Tj ET Q q 0 0 0 rg BT 501.06 384.45 Td (marketing ) Tj ET Q q 0 0 0 rg BT 543.40 384.45 Td (fees, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 372.45 Td (outsourcing ) Tj ET Q q 0 0 0 rg BT 88.24 372.45 Td (fees, ) Tj ET Q q 0 0 0 rg BT 111.86 372.45 Td (shipping ) Tj ET Q q 0 0 0 rg BT 151.32 372.45 Td (and ) Tj ET Q q 0 0 0 rg BT 170.78 372.45 Td (handling ) Tj ET Q q 0 0 0 rg BT 210.80 372.45 Td (costs, ) Tj ET Q q 0 0 0 rg BT 238.32 372.45 Td (advertising ) Tj ET Q q 0 0 0 rg BT 287.77 372.45 Td (and ) Tj ET Q q 0 0 0 rg BT 307.23 372.45 Td (product ) Tj ET Q q 0 0 0 rg BT 342.80 372.45 Td (promotion. ) Tj ET Q q 0 0 0 rg BT 391.98 372.45 Td (Expenses ) Tj ET Q q 0 0 0 rg BT 434.77 372.45 Td (are ) Tj ET Q q 0 0 0 rg BT 452.00 372.45 Td (managed ) Tj ET Q q 0 0 0 rg BT 493.11 372.45 Td (through ) Tj ET Q q 0 0 0 rg BT 529.24 372.45 Td (regional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 360.45 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 113.18 360.45 Td (or) Tj ET Q q 0 0 0 rg BT 121.33 360.45 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 169.65 360.45 Td (or ) Tj ET Q q 0 0 0 rg BT 180.76 360.45 Td (global ) Tj ET Q q 0 0 0 rg BT 208.53 360.45 Td (enabling ) Tj ET Q q 0 0 0 rg BT 245.73 360.45 Td (functions ) Tj ET Q q 0 0 0 rg BT 285.73 360.45 Td (such ) Tj ET Q q 0 0 0 rg BT 306.83 360.45 Td (as ) Tj ET Q q 0 0 0 rg BT 317.94 360.45 Td (finance, ) Tj ET Q q 0 0 0 rg BT 352.63 360.45 Td (legal, ) Tj ET Q q 0 0 0 rg BT 377.34 360.45 Td (information ) Tj ET Q q 0 0 0 rg BT 427.33 360.45 Td (technology ) Tj ET Q q 0 0 0 rg BT 474.54 360.45 Td (and ) Tj ET Q q 0 0 0 rg BT 491.75 360.45 Td (human ) Tj ET Q q 0 0 0 rg BT 521.74 360.45 Td (resources. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 348.45 Td (Certain ) Tj ET Q q 0 0 0 rg BT 67.82 348.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 106.30 348.45 Td (are ) Tj ET Q q 0 0 0 rg BT 120.89 348.45 Td (shared ) Tj ET Q q 0 0 0 rg BT 149.38 348.45 Td (with ) Tj ET Q q 0 0 0 rg BT 169.54 348.45 Td (alliance ) Tj ET Q q 0 0 0 rg BT 203.01 348.45 Td (partners ) Tj ET Q q 0 0 0 rg BT 237.60 348.45 Td (based ) Tj ET Q q 0 0 0 rg BT 262.75 348.45 Td (upon ) Tj ET Q q 0 0 0 rg BT 285.14 348.45 Td (contractual ) Tj ET Q q 0 0 0 rg BT 331.94 348.45 Td (agreements. ) Tj ET Q q 0 0 0 rg BT 382.36 348.45 Td (Expenses ) Tj ET Q q 0 0 0 rg BT 422.51 348.45 Td (typically ) Tj ET Q q 0 0 0 rg BT 459.89 348.45 Td (vary ) Tj ET Q q 0 0 0 rg BT 480.04 348.45 Td (between ) Tj ET Q q 0 0 0 rg BT 515.74 348.45 Td (periods ) Tj ET Q q 0 0 0 rg BT 547.56 348.45 Td (due ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 336.45 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 336.45 Td (new ) Tj ET Q q 0 0 0 rg BT 65.44 336.45 Td (product ) Tj ET Q q 0 0 0 rg BT 98.49 336.45 Td (launch ) Tj ET Q q 0 0 0 rg BT 127.64 336.45 Td (promotional ) Tj ET Q q 0 0 0 rg BT 179.02 336.45 Td (activities.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 318.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 318.45 Td (Marketing, ) Tj ET Q q 0 0 0 rg BT 107.34 318.45 Td (selling ) Tj ET Q q 0 0 0 rg BT 135.83 318.45 Td (and ) Tj ET Q q 0 0 0 rg BT 152.10 318.45 Td (administrative ) Tj ET Q q 0 0 0 rg BT 211.14 318.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 249.07 318.45 Td (decreased ) Tj ET Q q 0 0 0 rg BT 290.31 318.45 Td (in ) Tj ET Q q 0 0 0 rg BT 299.92 318.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 321.76 318.45 Td (due ) Tj ET Q q 0 0 0 rg BT 338.02 318.45 Td (to ) Tj ET Q q 0 0 0 rg BT 347.63 318.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 372.23 318.45 Td (advertising, ) Tj ET Q q 0 0 0 rg BT 421.00 318.45 Td (promotion ) Tj ET Q q 0 0 0 rg BT 464.49 318.45 Td (and ) Tj ET Q q 0 0 0 rg BT 480.76 318.45 Td (sales-force ) Tj ET Q q 0 0 0 rg BT 525.90 318.45 Td (expenses ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 306.45 Td (supporting ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 106.63 306.45 Td (Daklinza) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 142.74 306.45 Td ( ) Tj ET Q q 0 0 0 rg BT 145.24 306.45 Td (and ) Tj ET Q q 0 0 0 rg BT 162.18 306.45 Td (other ) Tj ET Q q 0 0 0 rg BT 185.22 306.45 Td (established ) Tj ET Q q 0 0 0 rg BT 232.16 306.45 Td (brands ) Tj ET Q q 0 0 0 rg BT 261.32 306.45 Td (and ) Tj ET Q q 0 0 0 rg BT 278.25 306.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 303.52 306.45 Td (BMS ) Tj ET Q q 0 0 0 rg BT 327.15 306.45 Td (foundation ) Tj ET Q q 0 0 0 rg BT 372.97 306.45 Td (grants.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 288.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 288.45 Td (Marketing, ) Tj ET Q q 0 0 0 rg BT 107.26 288.45 Td (selling ) Tj ET Q q 0 0 0 rg BT 135.68 288.45 Td (and ) Tj ET Q q 0 0 0 rg BT 151.88 288.45 Td (administrative ) Tj ET Q q 0 0 0 rg BT 210.84 288.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 248.70 288.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 288.21 288.45 Td (in ) Tj ET Q q 0 0 0 rg BT 297.74 288.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 319.50 288.45 Td (due ) Tj ET Q q 0 0 0 rg BT 335.70 288.45 Td (to ) Tj ET Q q 0 0 0 rg BT 345.23 288.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 372.54 288.45 Td (advertising, ) Tj ET Q q 0 0 0 rg BT 421.23 288.45 Td (promotion ) Tj ET Q q 0 0 0 rg BT 464.65 288.45 Td (and ) Tj ET Q q 0 0 0 rg BT 480.84 288.45 Td (sales-force ) Tj ET Q q 0 0 0 rg BT 525.91 288.45 Td (expenses ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 276.45 Td (supporting ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 106.63 276.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 136.07 276.45 Td ( ) Tj ET Q q 0 0 0 rg BT 138.57 276.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 174.39 276.45 Td (of) Tj ET Q q 0 0 0 rg BT 182.54 276.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 199.47 276.45 Td (by ) Tj ET Q q 0 0 0 rg BT 211.97 276.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 237.24 276.45 Td (spend ) Tj ET Q q 0 0 0 rg BT 263.07 276.45 Td (for ) Tj ET Q q 0 0 0 rg BT 277.23 276.45 Td (established ) Tj ET Q q 0 0 0 rg BT 324.17 276.45 Td (brands ) Tj ET Q q 0 0 0 rg BT 353.33 276.45 Td (and ) Tj ET Q q 0 0 0 rg BT 370.27 276.45 Td (favorable ) Tj ET Q q 0 0 0 rg BT 410.52 276.45 Td (foreign ) Tj ET Q q 0 0 0 rg BT 441.90 276.45 Td (exchange.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 251.11699218750005 m 143.3681640625 251.11699218750005 l s q 0 0 0 rg BT 36.00 252.45 Td (Resear) Tj ET Q q 0 0 0 rg BT 63.40 252.45 Td (ch ) Tj ET Q q 0 0 0 rg BT 75.34 252.45 Td (and ) Tj ET Q q 0 0 0 rg BT 92.84 252.45 Td (development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.45 Td (Research ) Tj ET Q q 0 0 0 rg BT 74.87 228.45 Td (and ) Tj ET Q q 0 0 0 rg BT 91.54 228.45 Td (development ) Tj ET Q q 0 0 0 rg BT 145.42 228.45 Td (activities ) Tj ET Q q 0 0 0 rg BT 183.75 228.45 Td (include ) Tj ET Q q 0 0 0 rg BT 215.41 228.45 Td (discovery ) Tj ET Q q 0 0 0 rg BT 256.52 228.45 Td (research, ) Tj ET Q q 0 0 0 rg BT 294.55 228.45 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 338.98 228.45 Td (and ) Tj ET Q q 0 0 0 rg BT 355.65 228.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 387.30 228.45 Td (development, ) Tj ET Q q 0 0 0 rg BT 443.68 228.45 Td (drug ) Tj ET Q q 0 0 0 rg BT 464.24 228.45 Td (formulation ) Tj ET Q q 0 0 0 rg BT 513.68 228.45 Td (and ) Tj ET Q q 0 0 0 rg BT 530.35 228.45 Td (medical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.45 Td (support ) Tj ET Q q 0 0 0 rg BT 70.25 216.45 Td (of ) Tj ET Q q 0 0 0 rg BT 82.83 216.45 Td (marketed ) Tj ET Q q 0 0 0 rg BT 124.29 216.45 Td (products. ) Tj ET Q q 0 0 0 rg BT 165.48 216.45 Td (Expenses ) Tj ET Q q 0 0 0 rg BT 207.50 216.45 Td (include ) Tj ET Q q 0 0 0 rg BT 241.18 216.45 Td (salary ) Tj ET Q q 0 0 0 rg BT 269.31 216.45 Td (and ) Tj ET Q q 0 0 0 rg BT 288.00 216.45 Td (benefit ) Tj ET Q q 0 0 0 rg BT 320.02 216.45 Td (costs, ) Tj ET Q q 0 0 0 rg BT 346.77 216.45 Td (third-party ) Tj ET Q q 0 0 0 rg BT 393.79 216.45 Td (grants ) Tj ET Q q 0 0 0 rg BT 422.48 216.45 Td (and ) Tj ET Q q 0 0 0 rg BT 441.17 216.45 Td (fees ) Tj ET Q q 0 0 0 rg BT 461.52 216.45 Td (paid ) Tj ET Q q 0 0 0 rg BT 482.99 216.45 Td (to ) Tj ET Q q 0 0 0 rg BT 495.02 216.45 Td (clinical ) Tj ET Q q 0 0 0 rg BT 528.70 216.45 Td (research ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.45 Td (or) Tj ET Q q 0 0 0 rg BT 44.15 204.45 Td (ganizations, ) Tj ET Q q 0 0 0 rg BT 94.05 204.45 Td (supplies, ) Tj ET Q q 0 0 0 rg BT 131.19 204.45 Td (upfront ) Tj ET Q q 0 0 0 rg BT 162.48 204.45 Td (and ) Tj ET Q q 0 0 0 rg BT 178.78 204.45 Td (contingent ) Tj ET Q q 0 0 0 rg BT 222.85 204.45 Td (milestone ) Tj ET Q q 0 0 0 rg BT 263.59 204.45 Td (payments ) Tj ET Q q 0 0 0 rg BT 303.77 204.45 Td (for ) Tj ET Q q 0 0 0 rg BT 317.29 204.45 Td (licensing ) Tj ET Q q 0 0 0 rg BT 355.25 204.45 Td (and ) Tj ET Q q 0 0 0 rg BT 371.55 204.45 Td (asset ) Tj ET Q q 0 0 0 rg BT 392.84 204.45 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 442.47 204.45 Td (of ) Tj ET Q q 0 0 0 rg BT 452.66 204.45 Td (investigational ) Tj ET Q q 0 0 0 rg BT 513.40 204.45 Td (compounds, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 192.45 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 62.63 192.45 Td (impairment ) Tj ET Q q 0 0 0 rg BT 112.57 192.45 Td (char) Tj ET Q q 0 0 0 rg BT 129.59 192.45 Td (ges ) Tj ET Q q 0 0 0 rg BT 146.76 192.45 Td (and ) Tj ET Q q 0 0 0 rg BT 165.04 192.45 Td (proportionate ) Tj ET Q q 0 0 0 rg BT 222.76 192.45 Td (allocations ) Tj ET Q q 0 0 0 rg BT 269.92 192.45 Td (of ) Tj ET Q q 0 0 0 rg BT 282.09 192.45 Td (enterprise-wide ) Tj ET Q q 0 0 0 rg BT 348.13 192.45 Td (costs. ) Tj ET Q q 0 0 0 rg BT 374.19 192.45 Td (The ) Tj ET Q q 0 0 0 rg BT 393.58 192.45 Td (allocations ) Tj ET Q q 0 0 0 rg BT 440.74 192.45 Td (include ) Tj ET Q q 0 0 0 rg BT 474.02 192.45 Td (facilities, ) Tj ET Q q 0 0 0 rg BT 514.79 192.45 Td (information ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 180.45 Td (technology) Tj ET Q q 0 0 0 rg BT 79.78 180.45 Td (, ) Tj ET Q q 0 0 0 rg BT 84.38 180.45 Td (employee ) Tj ET Q q 0 0 0 rg BT 125.34 180.45 Td (stock ) Tj ET Q q 0 0 0 rg BT 148.55 180.45 Td (compensation ) Tj ET Q q 0 0 0 rg BT 206.18 180.45 Td (costs ) Tj ET Q q 0 0 0 rg BT 228.28 180.45 Td (and ) Tj ET Q q 0 0 0 rg BT 244.81 180.45 Td (other ) Tj ET Q q 0 0 0 rg BT 267.45 180.45 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 315.07 180.45 Td (costs. ) Tj ET Q q 0 0 0 rg BT 339.67 180.45 Td (Certain ) Tj ET Q q 0 0 0 rg BT 371.20 180.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 409.39 180.45 Td (are ) Tj ET Q q 0 0 0 rg BT 423.69 180.45 Td (shared ) Tj ET Q q 0 0 0 rg BT 451.88 180.45 Td (with ) Tj ET Q q 0 0 0 rg BT 471.75 180.45 Td (alliance ) Tj ET Q q 0 0 0 rg BT 504.94 180.45 Td (partners ) Tj ET Q q 0 0 0 rg BT 539.24 180.45 Td (based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 168.45 Td (upon ) Tj ET Q q 0 0 0 rg BT 58.56 168.45 Td (contractual ) Tj ET Q q 0 0 0 rg BT 105.55 168.45 Td (agreements. ) Tj ET Q q 0 0 0 rg BT 156.15 168.45 Td (Expenses ) Tj ET Q q 0 0 0 rg BT 196.48 168.45 Td (typically ) Tj ET Q q 0 0 0 rg BT 234.03 168.45 Td (vary ) Tj ET Q q 0 0 0 rg BT 254.37 168.45 Td (between ) Tj ET Q q 0 0 0 rg BT 290.25 168.45 Td (periods ) Tj ET Q q 0 0 0 rg BT 322.25 168.45 Td (for ) Tj ET Q q 0 0 0 rg BT 336.48 168.45 Td (a ) Tj ET Q q 0 0 0 rg BT 343.48 168.45 Td (number ) Tj ET Q q 0 0 0 rg BT 376.59 168.45 Td (of ) Tj ET Q q 0 0 0 rg BT 387.49 168.45 Td (reasons, ) Tj ET Q q 0 0 0 rg BT 422.54 168.45 Td (including ) Tj ET Q q 0 0 0 rg BT 462.88 168.45 Td (the ) Tj ET Q q 0 0 0 rg BT 477.66 168.45 Td (timing ) Tj ET Q q 0 0 0 rg BT 506.34 168.45 Td (of ) Tj ET Q q 0 0 0 rg BT 517.24 168.45 Td (license ) Tj ET Q q 0 0 0 rg BT 547.56 168.45 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 156.45 Td (asset ) Tj ET Q q 0 0 0 rg BT 57.94 156.45 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 104.32 156.45 Td (char) Tj ET Q q 0 0 0 rg BT 121.35 156.45 Td (ges ) Tj ET Q q 0 0 0 rg BT 137.18 156.45 Td (and ) Tj ET Q q 0 0 0 rg BT 154.12 156.45 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 179.40 156.45 Td (impairment ) Tj ET Q q 0 0 0 rg BT 228.00 156.45 Td (char) Tj ET Q q 0 0 0 rg BT 245.02 156.45 Td (ges.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 138.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 138.45 Td (Research ) Tj ET Q q 0 0 0 rg BT 100.84 138.45 Td (and ) Tj ET Q q 0 0 0 rg BT 118.13 138.45 Td (development ) Tj ET Q q 0 0 0 rg BT 172.62 138.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 211.57 138.45 Td (increased ) Tj ET Q q 0 0 0 rg BT 252.17 138.45 Td (in ) Tj ET Q q 0 0 0 rg BT 262.80 138.45 Td (2017 ) Tj ET Q q 0 0 0 rg BT 285.64 138.45 Td (due ) Tj ET Q q 0 0 0 rg BT 302.93 138.45 Td (to ) Tj ET Q q 0 0 0 rg BT 313.55 138.45 Td (higher ) Tj ET Q q 0 0 0 rg BT 341.95 138.45 Td (license ) Tj ET Q q 0 0 0 rg BT 372.56 138.45 Td (and ) Tj ET Q q 0 0 0 rg BT 389.84 138.45 Td (asset ) Tj ET Q q 0 0 0 rg BT 412.13 138.45 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 458.85 138.45 Td (char) Tj ET Q q 0 0 0 rg BT 475.88 138.45 Td (ges, ) Tj ET Q q 0 0 0 rg BT 494.56 138.45 Td (site ) Tj ET Q q 0 0 0 rg BT 511.29 138.45 Td (exit ) Tj ET Q q 0 0 0 rg BT 529.13 138.45 Td (char) Tj ET Q q 0 0 0 rg BT 546.16 138.45 Td (ges, ) Tj ET Q q 0 0 0 rg BT 564.49 138.45 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 126.45 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 86.63 126.45 Td (impairment ) Tj ET Q q 0 0 0 rg BT 135.23 126.45 Td (char) Tj ET Q q 0 0 0 rg BT 152.26 126.45 Td (ges ) Tj ET Q q 0 0 0 rg BT 168.09 126.45 Td (and ) Tj ET Q q 0 0 0 rg BT 185.03 126.45 Td (expansion ) Tj ET Q q 0 0 0 rg BT 228.07 126.45 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 238.90 126.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.34 126.45 Td ( ) Tj ET Q q 0 0 0 rg BT 270.84 126.45 Td (and ) Tj ET Q q 0 0 0 rg BT 287.78 126.45 Td (other ) Tj ET Q q 0 0 0 rg BT 310.83 126.45 Td (IO ) Tj ET Q q 0 0 0 rg BT 323.88 126.45 Td (development ) Tj ET Q q 0 0 0 rg BT 378.03 126.45 Td (programs. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.35 108.45 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 108.45 Td (Research ) Tj ET Q q 0 0 0 rg BT 99.64 108.45 Td (and ) Tj ET Q q 0 0 0 rg BT 115.72 108.45 Td (development ) Tj ET Q q 0 0 0 rg BT 169.01 108.45 Td (expenses ) Tj ET Q q 0 0 0 rg BT 206.76 108.45 Td (decreased ) Tj ET Q q 0 0 0 rg BT 247.81 108.45 Td (in ) Tj ET Q q 0 0 0 rg BT 257.23 108.45 Td (2016 ) Tj ET Q q 0 0 0 rg BT 278.88 108.45 Td (due ) Tj ET Q q 0 0 0 rg BT 294.96 108.45 Td (to ) Tj ET Q q 0 0 0 rg BT 304.38 108.45 Td (lower ) Tj ET Q q 0 0 0 rg BT 328.79 108.45 Td (license ) Tj ET Q q 0 0 0 rg BT 358.20 108.45 Td (and ) Tj ET Q q 0 0 0 rg BT 374.28 108.45 Td (asset ) Tj ET Q q 0 0 0 rg BT 395.36 108.45 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 440.89 108.45 Td (and ) Tj ET Q q 0 0 0 rg BT 456.97 108.45 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 481.39 108.45 Td (impairment ) Tj ET Q q 0 0 0 rg BT 529.14 108.45 Td (char) Tj ET Q q 0 0 0 rg BT 546.16 108.45 Td (ges, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.35 96.45 Td (partially ) Tj ET Q q 0 0 0 rg BT 97.17 96.45 Td (of) Tj ET Q q 0 0 0 rg BT 105.32 96.45 Td (fset ) Tj ET Q q 0 0 0 rg BT 122.26 96.45 Td (by ) Tj ET Q q 0 0 0 rg BT 134.76 96.45 Td (the ) Tj ET Q q 0 0 0 rg BT 149.47 96.45 Td (acceleration ) Tj ET Q q 0 0 0 rg BT 200.27 96.45 Td (and ) Tj ET Q q 0 0 0 rg BT 217.21 96.45 Td (expansion ) Tj ET Q q 0 0 0 rg BT 260.26 96.45 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 271.09 96.45 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.52 96.45 Td ( ) Tj ET Q q 0 0 0 rg BT 303.02 96.45 Td (development ) Tj ET Q q 0 0 0 rg BT 357.18 96.45 Td (programs.) 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l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 476.6 m 465.5 476.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 476.6 m 547.5 476.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 409.6 m 383.5 409.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 409.6 m 465.5 409.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 409.6 m 547.5 409.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 357.6 m 383.5 357.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 357.6 m 465.5 357.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 357.6 m 547.5 357.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 335.6 m 383.5 335.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 321.6 m 383.5 321.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 319.6 m 383.5 319.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 335.6 m 465.5 335.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 321.6 m 465.5 321.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 402.5 319.6 m 465.5 319.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 335.6 m 547.5 335.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 321.6 m 547.5 321.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 484.5 319.6 m 547.5 319.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 720.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 389.20 720.83 Td (Y) Tj ET Q q 0 0 0 rg BT 394.53 720.83 Td (ear) Tj ET Q q 0 0 0 rg BT 405.12 720.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 465.85 720.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 705.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 351.00 705.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 433.00 705.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 507.50 705.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 691.27 Td (IFM) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.00 691.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 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Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 616.27 Td (50) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 386.00 621.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.65 616.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 616.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 601.27 Td (Ono) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 601.27 Td (40) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 386.00 606.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.65 601.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 601.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 586.27 Td (Padlock) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 586.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.65 586.27 Td (139) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 468.00 591.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 586.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 571.27 Td (Cormorant) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 571.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.65 571.27 Td (35) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 468.00 576.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 571.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 556.27 Td (Nitto Denko) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 556.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.65 556.27 Td (100) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 468.00 561.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 556.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 541.27 Td (Five Prime) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 541.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.65 541.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 541.27 Td (350) Tj ET Q BT /F1 6.50 Tf ET q 0 0 0 rg BT 550.00 546.43 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 526.27 Td (Promedior) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 526.27 Td (—) Tj ET Q BT 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0 rg BT 451.65 362.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 362.27 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 44.00 347.27 Td (Site exit costs and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.65 347.27 Td (383) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.65 347.27 Td (83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.65 347.27 Td (44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 44.00 325.27 Td (Research and development significant char) Tj ET Q q 0 0 0 rg BT 215.97 325.27 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.00 325.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.15 325.27 Td (1,588) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.00 325.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.65 325.27 Td (535) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.00 325.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.15 325.27 Td (1,883) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 311.50 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 54.00 311.50 Td (Upfront payment) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 301.90 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 54.00 301.90 Td (Milestone payment) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 292.30 Td (\(c\) ) Tj ET Q q 0 0 0 rg BT 54.00 292.30 Td (Option fee) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 268.30 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 268.30 Td (License ) Tj ET Q q 0 0 0 rg BT 104.40 268.30 Td (and ) Tj ET Q q 0 0 0 rg BT 120.15 268.30 Td (asset ) Tj ET Q q 0 0 0 rg BT 140.90 268.30 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 186.09 268.30 Td (char) Tj ET Q q 0 0 0 rg BT 203.11 268.30 Td (ges ) Tj ET Q q 0 0 0 rg BT 217.75 268.30 Td (resulted ) Tj ET Q q 0 0 0 rg BT 250.72 268.30 Td (from ) Tj ET Q q 0 0 0 rg BT 271.46 268.30 Td (strategic ) Tj ET Q q 0 0 0 rg BT 306.64 268.30 Td (transactions ) Tj ET Q q 0 0 0 rg BT 355.72 268.30 Td (to ) Tj ET Q q 0 0 0 rg BT 364.80 268.30 Td (acquire ) Tj ET Q q 0 0 0 rg BT 395.54 268.30 Td (or ) Tj ET Q q 0 0 0 rg BT 405.17 268.30 Td (license ) Tj ET Q q 0 0 0 rg BT 434.25 268.30 Td (certain ) Tj ET Q q 0 0 0 rg BT 462.76 268.30 Td (investigational ) Tj ET Q q 0 0 0 rg BT 522.94 268.30 Td (oncology) Tj ET Q q 0 0 0 rg BT 559.51 268.30 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 256.30 Td (cardiovascular) Tj ET Q q 0 0 0 rg BT 129.90 256.30 Td (, ) Tj ET Q q 0 0 0 rg BT 136.59 256.30 Td (immunoscience ) Tj ET Q q 0 0 0 rg BT 203.54 256.30 Td (and ) Tj ET Q q 0 0 0 rg BT 222.17 256.30 Td (fibrotic ) Tj ET Q q 0 0 0 rg BT 255.79 256.30 Td (disease ) Tj ET Q q 0 0 0 rg BT 288.86 256.30 Td (compounds ) Tj ET Q q 0 0 0 rg BT 339.15 256.30 Td (\(or ) Tj ET Q q 0 0 0 rg BT 355.00 256.30 Td (options ) Tj ET Q q 0 0 0 rg BT 388.64 256.30 Td (to ) Tj ET Q q 0 0 0 rg BT 400.61 256.30 Td (acquire ) Tj ET Q q 0 0 0 rg BT 434.22 256.30 Td (or ) Tj ET Q q 0 0 0 rg BT 446.74 256.30 Td (license\) ) Tj ET Q q 0 0 0 rg BT 482.02 256.30 Td (as ) Tj ET Q q 0 0 0 rg BT 494.54 256.30 Td (disclosed ) Tj ET Q q 0 0 0 rg BT 535.95 256.30 Td (in ) Tj ET Q q 0 0 0 rg BT 547.92 256.30 Td ("—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 244.30 Td (Acquisition ) Tj ET Q q 0 0 0 rg BT 121.17 244.30 Td (and ) Tj ET Q q 0 0 0 rg BT 138.10 244.30 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 179.49 244.30 Td (Arrangements".) 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Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 208.30 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 208.30 Td (Site ) Tj ET Q q 0 0 0 rg BT 90.26 208.30 Td (exit ) Tj ET Q q 0 0 0 rg BT 107.96 208.30 Td (costs ) Tj ET Q q 0 0 0 rg BT 130.67 208.30 Td (resulted ) Tj ET Q q 0 0 0 rg BT 165.03 208.30 Td (from ) Tj ET Q q 0 0 0 rg BT 187.18 208.30 Td (the ) Tj ET Q q 0 0 0 rg BT 202.10 208.30 Td (expected ) Tj ET Q q 0 0 0 rg BT 240.34 208.30 Td (exit ) Tj ET Q q 0 0 0 rg BT 258.04 208.30 Td (of ) Tj ET Q q 0 0 0 rg BT 269.08 208.30 Td (R&D ) Tj ET Q q 0 0 0 rg BT 293.46 208.30 Td (sites ) Tj ET Q q 0 0 0 rg BT 313.94 208.30 Td (in ) Tj ET Q q 0 0 0 rg BT 324.42 208.30 Td (the ) Tj ET Q q 0 0 0 rg BT 339.35 208.30 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 359.84 208.30 Td (through ) Tj ET Q q 0 0 0 rg BT 393.65 208.30 Td (2020 ) Tj ET Q q 0 0 0 rg BT 416.36 208.30 Td (primarily ) Tj ET Q q 0 0 0 rg BT 456.28 208.30 Td (due ) Tj ET Q q 0 0 0 rg BT 473.42 208.30 Td (to ) Tj ET Q q 0 0 0 rg BT 483.91 208.30 Td (the ) Tj ET Q q 0 0 0 rg BT 498.83 208.30 Td (reduction ) Tj ET Q q 0 0 0 rg BT 539.30 208.30 Td (in ) Tj ET Q q 0 0 0 rg BT 549.79 208.30 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 196.30 Td (estimated ) Tj ET Q q 0 0 0 rg BT 113.76 196.30 Td (useful ) Tj ET Q q 0 0 0 rg BT 141.63 196.30 Td (lives ) Tj ET Q q 0 0 0 rg BT 163.95 196.30 Td (of ) Tj ET Q q 0 0 0 rg BT 175.72 196.30 Td (the ) Tj ET Q q 0 0 0 rg BT 191.37 196.30 Td (related ) Tj ET Q q 0 0 0 rg BT 222.00 196.30 Td (assets ) Tj ET Q q 0 0 0 rg BT 248.77 196.30 Td (and ) Tj ET Q q 0 0 0 rg BT 266.64 196.30 Td (an ) Tj ET Q q 0 0 0 rg BT 279.52 196.30 Td (impairment ) Tj ET Q q 0 0 0 rg BT 329.05 196.30 Td (char) Tj ET Q q 0 0 0 rg BT 346.08 196.30 Td (ge ) Tj ET Q q 0 0 0 rg BT 358.95 196.30 Td (to ) Tj ET Q q 0 0 0 rg BT 370.16 196.30 Td (reduce ) Tj ET Q q 0 0 0 rg BT 400.24 196.30 Td (the ) Tj ET Q q 0 0 0 rg BT 415.90 196.30 Td (carrying ) Tj ET Q q 0 0 0 rg BT 452.65 196.30 Td (value ) Tj ET Q q 0 0 0 rg BT 477.74 196.30 Td (of ) Tj ET Q q 0 0 0 rg BT 489.50 196.30 Td (a ) Tj ET Q q 0 0 0 rg BT 497.38 196.30 Td (R&D ) Tj ET Q q 0 0 0 rg BT 522.48 196.30 Td (facility ) Tj ET Q q 0 0 0 rg BT 554.24 196.30 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 184.30 Td (W) Tj ET Q q 0 0 0 rg BT 80.64 184.30 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 125.07 184.30 Td (Connecticut.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 158.96699218749995 m 112.083984375 158.96699218749995 l s q 0 0 0 rg BT 36.00 160.30 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.83 160.30 Td (income ) Tj ET Q q 0 0 0 rg BT 93.21 160.30 Td (\(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 136.30 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 136.30 Td (Other ) Tj ET Q q 0 0 0 rg BT 97.45 136.30 Td (income ) Tj ET Q q 0 0 0 rg BT 129.57 136.30 Td (\(net\) ) Tj ET Q q 0 0 0 rg BT 151.13 136.30 Td (increased ) Tj ET Q q 0 0 0 rg BT 191.57 136.30 Td (in ) Tj ET Q q 0 0 0 rg BT 202.03 136.30 Td (2017 ) Tj ET Q q 0 0 0 rg BT 224.72 136.30 Td (primarily ) Tj ET Q q 0 0 0 rg BT 264.62 136.30 Td (due ) Tj ET Q q 0 0 0 rg BT 281.74 136.30 Td (to ) Tj ET Q q 0 0 0 rg BT 292.20 136.30 Td (a ) Tj ET Q q 0 0 0 rg BT 299.32 136.30 Td (patent ) Tj ET Q q 0 0 0 rg BT 326.44 136.30 Td (infringement ) Tj ET Q q 0 0 0 rg BT 380.78 136.30 Td (settlement ) Tj ET Q q 0 0 0 rg BT 424.56 136.30 Td (and ) Tj ET Q q 0 0 0 rg BT 441.68 136.30 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 496.58 136.30 Td (income ) Tj ET Q q 0 0 0 rg BT 528.70 136.30 Td (partially ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 124.30 Td (of) Tj ET Q q 0 0 0 rg BT 80.15 124.30 Td (fset ) Tj ET Q q 0 0 0 rg BT 97.09 124.30 Td (by ) Tj ET Q q 0 0 0 rg BT 109.59 124.30 Td (lower ) Tj ET Q q 0 0 0 rg BT 134.86 124.30 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 179.57 124.30 Td (gains ) Tj ET Q q 0 0 0 rg BT 203.18 124.30 Td (and ) Tj ET Q q 0 0 0 rg BT 220.12 124.30 Td (related ) Tj ET Q q 0 0 0 rg BT 249.82 124.30 Td (service ) Tj ET Q q 0 0 0 rg BT 280.63 124.30 Td (fees ) Tj ET Q q 0 0 0 rg BT 299.23 124.30 Td (and ) Tj ET Q q 0 0 0 rg BT 316.17 124.30 Td (higher ) Tj ET Q q 0 0 0 rg BT 344.22 124.30 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 397.81 124.30 Td (and ) Tj ET Q q 0 0 0 rg BT 414.75 124.30 Td (debt ) Tj ET Q q 0 0 0 rg BT 434.47 124.30 Td (redemption ) Tj ET Q q 0 0 0 rg BT 482.51 124.30 Td (char) Tj ET Q q 0 0 0 rg BT 499.53 124.30 Td (ges.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 112.30 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 112.30 Td (Other ) Tj ET Q q 0 0 0 rg BT 96.94 112.30 Td (income ) Tj ET Q q 0 0 0 rg BT 128.55 112.30 Td (\(net\) ) Tj ET Q q 0 0 0 rg BT 149.60 112.30 Td (increased ) Tj ET Q q 0 0 0 rg BT 189.52 112.30 Td (in ) Tj ET Q q 0 0 0 rg BT 199.48 112.30 Td (2016 ) Tj ET Q q 0 0 0 rg BT 221.65 112.30 Td (primarily ) Tj ET Q q 0 0 0 rg BT 261.03 112.30 Td (due ) Tj ET Q q 0 0 0 rg BT 277.64 112.30 Td (to ) Tj ET Q q 0 0 0 rg BT 287.60 112.30 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 331.98 112.30 Td (gains ) Tj ET Q q 0 0 0 rg BT 355.26 112.30 Td (and ) Tj ET Q q 0 0 0 rg BT 371.87 112.30 Td (related ) Tj ET Q q 0 0 0 rg BT 401.25 112.30 Td (service ) Tj ET Q q 0 0 0 rg BT 431.74 112.30 Td (fees ) Tj ET Q q 0 0 0 rg BT 450.01 112.30 Td (and ) Tj ET Q q 0 0 0 rg BT 466.62 112.30 Td (royalties ) Tj ET Q q 0 0 0 rg BT 503.23 112.30 Td (and ) Tj ET Q q 0 0 0 rg BT 519.84 112.30 Td (lower ) Tj ET Q q 0 0 0 rg BT 544.78 112.30 Td (debt ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 100.30 Td (redemption ) Tj ET Q q 0 0 0 rg BT 120.04 100.30 Td (and ) Tj ET Q q 0 0 0 rg BT 136.98 100.30 Td (litigation ) Tj ET Q q 0 0 0 rg BT 175.59 100.30 Td (char) Tj ET Q q 0 0 0 rg BT 192.62 100.30 Td (ges.) Tj ET Q endstream endobj 81 0 obj <> endobj 82 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 31.60 Td (40) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 742.10 Td (Components ) Tj ET Q q 0 0 0 rg BT 89.06 742.10 Td (of ) Tj ET Q q 0 0 0 rg BT 99.89 742.10 Td (other ) Tj ET Q q 0 0 0 rg BT 122.93 742.10 Td (income ) Tj ET Q q 0 0 0 rg BT 154.87 742.10 Td (\(net\) ) Tj ET Q q 0 0 0 rg BT 176.24 742.10 Td (were ) Tj ET Q q 0 0 0 rg BT 198.17 742.10 Td (as ) Tj ET Q q 0 0 0 rg BT 209.00 742.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 705.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 705.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 705.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 705.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 705.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 705.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 705.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 679.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 679.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 679.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 679.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 679.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 679.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 679.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 653.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 653.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 653.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 653.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 653.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 653.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 653.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 627.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 627.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 627.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 627.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 627.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 627.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 627.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 601.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 601.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 601.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 601.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 601.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 601.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 601.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 575.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 575.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 575.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 575.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 575.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 575.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 575.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 549.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 549.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 549.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 549.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 549.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 549.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 549.60 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 28.50 523.60 331.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 359.50 523.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 523.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 523.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 523.60 65.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 523.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 523.60 67.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 718.6 m 428.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 428.5 718.6 m 432.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 718.6 m 497.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 718.6 m 501.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 718.6 m 568.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 718.6 m 428.5 718.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 705.6 m 428.5 705.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 705.6 m 568.5 705.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 705.6 m 497.5 705.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 705.6 m 568.5 705.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 523.6 m 497.5 523.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 523.6 m 568.5 523.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 523.6 m 428.5 523.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 511.6 m 428.5 511.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 363.5 509.6 m 428.5 509.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 511.6 m 497.5 511.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 509.6 m 497.5 509.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 511.6 m 568.5 511.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 509.6 m 568.5 509.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 31.00 722.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.20 722.83 Td (Y) Tj ET Q q 0 0 0 rg BT 426.09 722.83 Td (ear) Tj ET Q q 0 0 0 rg BT 437.05 722.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 497.78 722.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 31.00 709.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.50 709.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 456.50 709.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 526.50 709.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 696.17 Td (Interest expense) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.00 696.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.65 696.17 Td (196) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 696.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 696.17 Td (167) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 696.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.65 696.17 Td (184) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 683.17 Td (Investment income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.30 683.22 Td (\(154) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 683.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 683.22 Td (\(105) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 683.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 683.17 Td (\(101) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 683.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 670.17 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.65 670.17 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 670.17 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.65 670.17 Td (1) Tj ET Q q 0 0 0 rg BT 554.65 670.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 657.17 Td (Litigation and other settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.30 657.22 Td (\(487) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 657.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 657.17 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.65 657.17 Td (159) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 644.17 Td (Equity in net income of af) Tj ET Q q 0 0 0 rg BT 135.60 644.17 Td (filiates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.30 644.22 Td (\(75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 644.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 644.22 Td (\(77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 644.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 551.30 644.17 Td (\(83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 644.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 631.17 Td (Divestiture gains) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.30 631.22 Td (\(164) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 631.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 631.22 Td (\(576) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 631.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 631.17 Td (\(196) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 631.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 618.17 Td (Royalties and licensing income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.80 618.22 Td (\(1,351) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 618.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 618.22 Td (\(719) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 618.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 618.17 Td (\(383) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 618.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 605.17 Td (T) Tj ET Q q 0 0 0 rg BT 36.93 605.17 Td (ransition and other service fees) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.30 605.22 Td (\(37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 605.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 605.22 Td (\(238) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 605.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 605.17 Td (\(122) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 605.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 592.17 Td (Pension char) Tj ET Q q 0 0 0 rg BT 82.29 592.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.65 592.17 Td (162) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 592.17 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.65 592.17 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 579.17 Td (Intangible asset impairment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.65 579.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 579.17 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.65 579.17 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 566.17 Td (Equity investment impairment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.65 566.17 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 566.17 Td (45) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.65 566.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 553.17 Td (W) Tj ET Q q 0 0 0 rg BT 40.24 553.17 Td (ritten option adjustment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.65 553.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 553.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 553.17 Td (\(123) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 553.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 540.17 Td (Loss on debt redemption) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.65 540.17 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 540.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.65 540.17 Td (180) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 527.17 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.30 527.22 Td (\(16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 527.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 527.22 Td (\(44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 527.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.65 527.17 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 31.00 514.17 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.00 514.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.80 514.22 Td (\(1,519) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 514.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 514.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.80 514.22 Td (\(1,285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 514.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 514.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 514.17 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.65 514.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 487.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 487.10 Td (Restructuring ) Tj ET Q q 0 0 0 rg BT 128.77 487.10 Td (char) Tj ET Q q 0 0 0 rg BT 145.80 487.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 161.46 487.10 Td (relate ) Tj ET Q q 0 0 0 rg BT 186.00 487.10 Td (to ) Tj ET Q q 0 0 0 rg BT 196.12 487.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 230.66 487.10 Td (to ) Tj ET Q q 0 0 0 rg BT 240.77 487.10 Td (the ) Tj ET Q q 0 0 0 rg BT 255.33 487.10 Td (Company's ) Tj ET Q q 0 0 0 rg BT 302.24 487.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 342.34 487.10 Td (model ) Tj ET Q q 0 0 0 rg BT 369.68 487.10 Td (to ) Tj ET Q q 0 0 0 rg BT 379.79 487.10 Td (drive ) Tj ET Q q 0 0 0 rg BT 402.67 487.10 Td (continued ) Tj ET Q q 0 0 0 rg BT 444.44 487.10 Td (success ) Tj ET Q q 0 0 0 rg BT 476.77 487.10 Td (in ) Tj ET Q q 0 0 0 rg BT 486.89 487.10 Td (the ) Tj ET Q q 0 0 0 rg BT 501.44 487.10 Td (near) Tj ET Q q 0 0 0 rg BT 518.45 487.10 Td (- ) Tj ET Q q 0 0 0 rg BT 524.11 487.10 Td (and ) Tj ET Q q 0 0 0 rg BT 540.89 487.10 Td (long-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 475.10 Td (term ) Tj ET Q q 0 0 0 rg BT 92.96 475.10 Td (through ) Tj ET Q q 0 0 0 rg BT 126.71 475.10 Td (a ) Tj ET Q q 0 0 0 rg BT 133.79 475.10 Td (more ) Tj ET Q q 0 0 0 rg BT 156.98 475.10 Td (focused ) Tj ET Q q 0 0 0 rg BT 190.71 475.10 Td (investment ) Tj ET Q q 0 0 0 rg BT 237.23 475.10 Td (in ) Tj ET Q q 0 0 0 rg BT 247.65 475.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 297.49 475.10 Td (opportunities ) Tj ET Q q 0 0 0 rg BT 352.90 475.10 Td (for ) Tj ET Q q 0 0 0 rg BT 367.20 475.10 Td (key ) Tj ET Q q 0 0 0 rg BT 384.28 475.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 413.58 475.10 Td (and ) Tj ET Q q 0 0 0 rg BT 430.65 475.10 Td (markets, ) Tj ET Q q 0 0 0 rg BT 467.45 475.10 Td (a ) Tj ET Q q 0 0 0 rg BT 474.53 475.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 524.37 475.10 Td (and ) Tj ET Q q 0 0 0 rg BT 541.45 475.10 Td (more ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 463.10 Td (agile ) Tj ET Q q 0 0 0 rg BT 94.22 463.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 118.67 463.10 Td (or) Tj ET Q q 0 0 0 rg BT 126.82 463.10 Td (ganization ) Tj ET Q q 0 0 0 rg BT 171.26 463.10 Td (that ) Tj ET Q q 0 0 0 rg BT 189.04 463.10 Td (can ) Tj ET Q q 0 0 0 rg BT 205.70 463.10 Td (accelerate ) Tj ET Q q 0 0 0 rg BT 248.45 463.10 Td (the ) Tj ET Q q 0 0 0 rg BT 263.45 463.10 Td (pipeline, ) Tj ET Q q 0 0 0 rg BT 300.95 463.10 Td (streamline ) Tj ET Q q 0 0 0 rg BT 345.38 463.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 389.82 463.10 Td (and ) Tj ET Q q 0 0 0 rg BT 407.05 463.10 Td (realign ) Tj ET Q q 0 0 0 rg BT 437.60 463.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 498.69 463.10 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 547.01 463.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 451.10 Td (broaden ) Tj ET Q q 0 0 0 rg BT 105.98 451.10 Td (biologics ) Tj ET Q q 0 0 0 rg BT 144.42 451.10 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 191.73 451.10 Td (to ) Tj ET Q q 0 0 0 rg BT 201.29 451.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 228.59 451.10 Td (the ) Tj ET Q q 0 0 0 rg BT 242.59 451.10 Td (current ) Tj ET Q q 0 0 0 rg BT 272.68 451.10 Td (and ) Tj ET Q q 0 0 0 rg BT 288.89 451.10 Td (future ) Tj ET Q q 0 0 0 rg BT 314.54 451.10 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 351.31 451.10 Td (as ) Tj ET Q q 0 0 0 rg BT 361.42 451.10 Td (well ) Tj ET Q q 0 0 0 rg BT 380.41 451.10 Td (as ) Tj ET Q q 0 0 0 rg BT 390.51 451.10 Td (streamline ) Tj ET Q q 0 0 0 rg BT 433.94 451.10 Td (and ) Tj ET Q q 0 0 0 rg BT 450.15 451.10 Td (simplify ) Tj ET Q q 0 0 0 rg BT 485.26 451.10 Td (our ) Tj ET Q q 0 0 0 rg BT 500.37 451.10 Td (small-molecule ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 439.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 100.20 439.10 Td (network. ) Tj ET Q q 0 0 0 rg BT 136.88 439.10 Td (The ) Tj ET Q q 0 0 0 rg BT 153.96 439.10 Td (new ) Tj ET Q q 0 0 0 rg BT 172.15 439.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 211.44 439.10 Td (model ) Tj ET Q q 0 0 0 rg BT 237.96 439.10 Td (is ) Tj ET Q q 0 0 0 rg BT 246.16 439.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 283.22 439.10 Td (to ) Tj ET Q q 0 0 0 rg BT 292.53 439.10 Td (enable ) Tj ET Q q 0 0 0 rg BT 320.15 439.10 Td (the ) Tj ET Q q 0 0 0 rg BT 333.90 439.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 374.31 439.10 Td (to ) Tj ET Q q 0 0 0 rg BT 383.62 439.10 Td (deliver ) Tj ET Q q 0 0 0 rg BT 412.91 439.10 Td (the ) Tj ET Q q 0 0 0 rg BT 426.66 439.10 Td (strategic, ) Tj ET Q q 0 0 0 rg BT 464.56 439.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 501.06 439.10 Td (and ) Tj ET Q q 0 0 0 rg BT 517.03 439.10 Td (operational ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 427.10 Td (flexibility ) Tj ET Q q 0 0 0 rg BT 113.77 427.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 154.97 427.10 Td (to ) Tj ET Q q 0 0 0 rg BT 165.08 427.10 Td (invest ) Tj ET Q q 0 0 0 rg BT 191.30 427.10 Td (in ) Tj ET Q q 0 0 0 rg BT 201.41 427.10 Td (the ) Tj ET Q q 0 0 0 rg BT 215.96 427.10 Td (highest ) Tj ET Q q 0 0 0 rg BT 247.17 427.10 Td (priorities ) Tj ET Q q 0 0 0 rg BT 285.61 427.10 Td (across ) Tj ET Q q 0 0 0 rg BT 312.93 427.10 Td (the ) Tj ET Q q 0 0 0 rg BT 327.48 427.10 Td (Company) Tj ET Q q 0 0 0 rg BT 365.72 427.10 Td (. ) Tj ET Q q 0 0 0 rg BT 370.03 427.10 Td (Aggregate ) Tj ET Q q 0 0 0 rg BT 414.01 427.10 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 467.44 427.10 Td (char) Tj ET Q q 0 0 0 rg BT 484.46 427.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 500.12 427.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.78 427.10 Td ($826 ) Tj ET Q q 0 0 0 rg BT 533.12 427.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 415.10 Td (have ) Tj ET Q q 0 0 0 rg BT 93.61 415.10 Td (been ) Tj ET Q q 0 0 0 rg BT 115.22 415.10 Td (incurred ) Tj ET Q q 0 0 0 rg BT 151.27 415.10 Td (in ) Tj ET Q q 0 0 0 rg BT 161.78 415.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 184.51 415.10 Td (for ) Tj ET Q q 0 0 0 rg BT 198.90 415.10 Td (all ) Tj ET Q q 0 0 0 rg BT 211.63 415.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 242.68 415.10 Td (including ) Tj ET Q q 0 0 0 rg BT 283.19 415.10 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 330.88 415.10 Td (depreciation ) Tj ET Q q 0 0 0 rg BT 383.03 415.10 Td (and ) Tj ET Q q 0 0 0 rg BT 400.20 415.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 449.03 415.10 Td (char) Tj ET Q q 0 0 0 rg BT 466.06 415.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 482.12 415.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 519.84 415.10 Td (from ) Tj ET Q q 0 0 0 rg BT 542.01 415.10 Td (early ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 403.10 Td (site ) Tj ET Q q 0 0 0 rg BT 88.39 403.10 Td (exits.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 391.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 391.10 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 113.91 391.10 Td (and ) Tj ET Q q 0 0 0 rg BT 130.82 391.10 Td (other ) Tj ET Q q 0 0 0 rg BT 153.84 391.10 Td (settlements ) Tj ET Q q 0 0 0 rg BT 201.30 391.10 Td (include ) Tj ET Q q 0 0 0 rg BT 233.21 391.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 262.50 391.10 Td (share ) Tj ET Q q 0 0 0 rg BT 286.07 391.10 Td (of ) Tj ET Q q 0 0 0 rg BT 296.87 391.10 Td (a ) Tj ET Q q 0 0 0 rg BT 303.78 391.10 Td (patent-infringement ) Tj ET Q q 0 0 0 rg BT 385.67 391.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 429.24 391.10 Td (related ) Tj ET Q q 0 0 0 rg BT 458.91 391.10 Td (to ) Tj ET Q q 0 0 0 rg BT 469.16 391.10 Td (Merck's ) Tj ET Q q 0 0 0 rg BT 503.43 391.10 Td (PD-1 ) Tj ET Q q 0 0 0 rg BT 527.01 391.10 Td (antibody ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 72.00 379.10 Td (Keytruda* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 116.75 379.10 Td (in ) Tj ET Q q 0 0 0 rg BT 127.07 379.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 149.60 379.10 Td (as ) Tj ET Q q 0 0 0 rg BT 160.47 379.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 184.13 379.10 Td (and ) Tj ET Q q 0 0 0 rg BT 201.11 379.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 220.86 379.10 Td (signed ) Tj ET Q q 0 0 0 rg BT 249.51 379.10 Td (a ) Tj ET Q q 0 0 0 rg BT 256.48 379.10 Td (global ) Tj ET Q q 0 0 0 rg BT 284.02 379.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 310.99 379.10 Td (license ) Tj ET Q q 0 0 0 rg BT 341.29 379.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 385.46 379.10 Td (with ) Tj ET Q q 0 0 0 rg BT 405.78 379.10 Td (Merck. ) Tj ET Q q 0 0 0 rg BT 436.91 379.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 465.55 379.10 Td (made ) Tj ET Q q 0 0 0 rg BT 489.74 379.10 Td (an ) Tj ET Q q 0 0 0 rg BT 501.72 379.10 Td (initial ) Tj ET Q q 0 0 0 rg BT 527.58 379.10 Td (payment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 367.10 Td (of ) Tj ET Q q 0 0 0 rg BT 83.08 367.10 Td ($625 ) Tj ET Q q 0 0 0 rg BT 105.84 367.10 Td (million ) Tj ET Q q 0 0 0 rg BT 137.48 367.10 Td (to ) Tj ET Q q 0 0 0 rg BT 148.01 367.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 171.89 367.10 Td (and ) Tj ET Q q 0 0 0 rg BT 189.08 367.10 Td (Ono, ) Tj ET Q q 0 0 0 rg BT 211.55 367.10 Td (of ) Tj ET Q q 0 0 0 rg BT 222.64 367.10 Td (which ) Tj ET Q q 0 0 0 rg BT 249.83 367.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 273.70 367.10 Td (received ) Tj ET Q q 0 0 0 rg BT 310.32 367.10 Td ($481 ) Tj ET Q q 0 0 0 rg BT 333.07 367.10 Td (million. ) Tj ET Q q 0 0 0 rg BT 367.22 367.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 396.07 367.10 Td (is ) Tj ET Q q 0 0 0 rg BT 405.49 367.10 Td (also ) Tj ET Q q 0 0 0 rg BT 424.35 367.10 Td (obligated ) Tj ET Q q 0 0 0 rg BT 464.32 367.10 Td (to ) Tj ET Q q 0 0 0 rg BT 474.85 367.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 492.04 367.10 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 527.57 367.10 Td (royalties ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 355.10 Td (on ) Tj ET Q q 0 0 0 rg BT 84.87 355.10 Td (global ) Tj ET Q q 0 0 0 rg BT 112.73 355.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 135.03 355.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 146.23 355.10 Td (Keytruda*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 188.45 355.10 Td ( ) Tj ET Q q 0 0 0 rg BT 191.31 355.10 Td (of ) Tj ET Q q 0 0 0 rg BT 202.51 355.10 Td (6.5% ) Tj ET Q q 0 0 0 rg BT 226.20 355.10 Td (from ) Tj ET Q q 0 0 0 rg BT 248.51 355.10 Td (January ) Tj ET Q q 0 0 0 rg BT 282.47 355.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 292.84 355.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 315.71 355.10 Td (through ) Tj ET Q q 0 0 0 rg BT 349.68 355.10 Td (December ) Tj ET Q q 0 0 0 rg BT 393.63 355.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 409.00 355.10 Td (2023, ) Tj ET Q q 0 0 0 rg BT 434.36 355.10 Td (and ) Tj ET Q q 0 0 0 rg BT 451.67 355.10 Td (2.5% ) Tj ET Q q 0 0 0 rg BT 475.36 355.10 Td (from ) Tj ET Q q 0 0 0 rg BT 497.67 355.10 Td (January ) Tj ET Q q 0 0 0 rg BT 531.63 355.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 542.00 355.10 Td (2024 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 343.10 Td (through ) Tj ET Q q 0 0 0 rg BT 105.29 343.10 Td (December ) Tj ET Q q 0 0 0 rg BT 148.55 343.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 163.22 343.10 Td (2026. ) Tj ET Q q 0 0 0 rg BT 187.74 343.10 Td (The ) Tj ET Q q 0 0 0 rg BT 205.47 343.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 250.41 343.10 Td (also ) Tj ET Q q 0 0 0 rg BT 268.69 343.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 300.85 343.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 330.23 343.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 355.19 343.10 Td (to ) Tj ET Q q 0 0 0 rg BT 365.14 343.10 Td (each ) Tj ET Q q 0 0 0 rg BT 385.63 343.10 Td (other ) Tj ET Q q 0 0 0 rg BT 408.36 343.10 Td (under ) Tj ET Q q 0 0 0 rg BT 433.30 343.10 Td (their ) Tj ET Q q 0 0 0 rg BT 453.81 343.10 Td (respective ) Tj ET Q q 0 0 0 rg BT 496.51 343.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 523.12 343.10 Td (portfolios ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 331.10 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 115.43 331.10 Td (to ) Tj ET Q q 0 0 0 rg BT 126.09 331.10 Td (PD-1. ) Tj ET Q q 0 0 0 rg BT 152.59 331.10 Td (Payments ) Tj ET Q q 0 0 0 rg BT 194.36 331.10 Td (and ) Tj ET Q q 0 0 0 rg BT 211.68 331.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 249.00 331.10 Td (are ) Tj ET Q q 0 0 0 rg BT 264.09 331.10 Td (shared ) Tj ET Q q 0 0 0 rg BT 293.08 331.10 Td (between ) Tj ET Q q 0 0 0 rg BT 329.28 331.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 353.28 331.10 Td (and ) Tj ET Q q 0 0 0 rg BT 370.61 331.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 390.71 331.10 Td (on ) Tj ET Q q 0 0 0 rg BT 403.60 331.10 Td (a ) Tj ET Q q 0 0 0 rg BT 410.92 331.10 Td (75/25 ) Tj ET Q q 0 0 0 rg BT 436.58 331.10 Td (percent ) Tj ET Q q 0 0 0 rg BT 468.89 331.10 Td (allocation, ) Tj ET Q q 0 0 0 rg BT 513.71 331.10 Td (respectively ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 319.10 Td (after ) Tj ET Q q 0 0 0 rg BT 92.82 319.10 Td (adjusting ) Tj ET Q q 0 0 0 rg BT 131.98 319.10 Td (for ) Tj ET Q q 0 0 0 rg BT 146.14 319.10 Td (each ) Tj ET Q q 0 0 0 rg BT 166.96 319.10 Td (parties' ) Tj ET Q q 0 0 0 rg BT 197.91 319.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 219.85 319.10 Td (fees.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 307.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 307.10 Td (Divestiture ) Tj ET Q q 0 0 0 rg BT 119.51 307.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 143.70 307.10 Td (relate ) Tj ET Q q 0 0 0 rg BT 168.99 307.10 Td (to ) Tj ET Q q 0 0 0 rg BT 179.85 307.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 222.92 307.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 268.21 307.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 325.16 307.10 Td (for ) Tj ET Q q 0 0 0 rg BT 339.91 307.10 Td (the ) Tj ET Q q 0 0 0 rg BT 355.20 307.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 391.05 307.10 Td (business ) Tj ET Q q 0 0 0 rg BT 428.02 307.10 Td (in ) Tj ET Q q 0 0 0 rg BT 438.88 307.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 464.46 307.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 494.74 307.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 517.83 307.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 547.57 307.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 295.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 132.42 295.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 150.01 295.10 Td ( ) Tj ET Q q 0 0 0 rg BT 151.56 295.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 193.65 295.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 237.41 295.10 Td (in ) Tj ET Q q 0 0 0 rg BT 246.73 295.10 Td (2016, ) Tj ET Q q 0 0 0 rg BT 270.78 295.10 Td (and ) Tj ET Q q 0 0 0 rg BT 286.76 295.10 Td (the ) Tj ET Q q 0 0 0 rg BT 300.52 295.10 Td (Mount ) Tj ET Q q 0 0 0 rg BT 328.63 295.10 Td (V) Tj ET Q q 0 0 0 rg BT 334.74 295.10 Td (ernon, ) Tj ET Q q 0 0 0 rg BT 361.55 295.10 Td (Indiana ) Tj ET Q q 0 0 0 rg BT 393.08 295.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 452.94 295.10 Td (facility) Tj ET Q q 0 0 0 rg BT 480.61 295.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 484.65 295.10 Td (Erbitux*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.65 295.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 523.69 295.10 Td (Ixempra*) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 283.10 Td (and ) Tj ET Q q 0 0 0 rg BT 88.94 283.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 118.64 283.10 Td (other ) Tj ET Q q 0 0 0 rg BT 141.69 283.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 164.19 283.10 Td (product ) Tj ET Q q 0 0 0 rg BT 197.23 283.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 241.96 283.10 Td (in ) Tj ET Q q 0 0 0 rg BT 252.23 283.10 Td (2015. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 271.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 271.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 112.21 271.10 Td (and ) Tj ET Q q 0 0 0 rg BT 129.09 271.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 167.63 271.10 Td (income ) Tj ET Q q 0 0 0 rg BT 199.50 271.10 Td (include ) Tj ET Q q 0 0 0 rg BT 231.37 271.10 Td (upfront ) Tj ET Q q 0 0 0 rg BT 263.25 271.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 301.79 271.10 Td (fees ) Tj ET Q q 0 0 0 rg BT 320.33 271.10 Td (from ) Tj ET Q q 0 0 0 rg BT 342.20 271.10 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 373.53 271.10 Td (and ) Tj ET Q q 0 0 0 rg BT 390.40 271.10 Td (Roche ) Tj ET Q q 0 0 0 rg BT 418.39 271.10 Td (in ) Tj ET Q q 0 0 0 rg BT 428.61 271.10 Td (connection ) Tj ET Q q 0 0 0 rg BT 474.92 271.10 Td (with ) Tj ET Q q 0 0 0 rg BT 495.13 271.10 Td (the ) Tj ET Q q 0 0 0 rg BT 509.79 271.10 Td (out-licensing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 259.10 Td (of ) Tj ET Q q 0 0 0 rg BT 83.77 259.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 114.42 259.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 176.74 259.10 Td (genetically ) Tj ET Q q 0 0 0 rg BT 224.05 259.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 257.48 259.10 Td (disease ) Tj ET Q q 0 0 0 rg BT 289.80 259.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 339.35 259.10 Td (in ) Tj ET Q q 0 0 0 rg BT 350.58 259.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 376.52 259.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 414.40 259.10 Td (from ) Tj ET Q q 0 0 0 rg BT 437.28 259.10 Td (the ) Tj ET Q q 0 0 0 rg BT 452.94 259.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 482.48 259.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 510.36 259.10 Td (infringement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 247.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 116.35 247.10 Td (in ) Tj ET Q q 0 0 0 rg BT 127.38 247.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 150.64 247.10 Td (and ) Tj ET Q q 0 0 0 rg BT 168.33 247.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 213.79 247.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 270.92 247.10 Td (from ) Tj ET Q q 0 0 0 rg BT 293.61 247.10 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 309.08 247.10 Td (Erbitux* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.33 247.10 Td (and ) Tj ET Q q 0 0 0 rg BT 365.02 247.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 401.04 247.10 Td (business ) Tj ET Q q 0 0 0 rg BT 438.18 247.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 487.54 247.10 Td (in ) Tj ET Q q 0 0 0 rg BT 498.57 247.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 524.33 247.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 547.58 247.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 235.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 97.00 235.10 Td (including ) Tj ET Q q 0 0 0 rg BT 137.27 235.10 Td (the ) Tj ET Q q 0 0 0 rg BT 151.99 235.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 185.03 235.10 Td (of ) Tj ET Q q 0 0 0 rg BT 195.86 235.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 225.56 235.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 256.38 235.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 281.66 235.10 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 324.71 235.10 Td (to ) Tj ET Q q 0 0 0 rg BT 334.43 235.10 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 367.49 235.10 Td (product ) Tj ET Q q 0 0 0 rg BT 400.54 235.10 Td (sales.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 223.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 223.10 Td (T) Tj ET Q q 0 0 0 rg BT 77.76 223.10 Td (ransition ) Tj ET Q q 0 0 0 rg BT 114.26 223.10 Td (and ) Tj ET Q q 0 0 0 rg BT 130.21 223.10 Td (other ) Tj ET Q q 0 0 0 rg BT 152.27 223.10 Td (service ) Tj ET Q q 0 0 0 rg BT 182.10 223.10 Td (fees ) Tj ET Q q 0 0 0 rg BT 199.71 223.10 Td (included ) Tj ET Q q 0 0 0 rg BT 235.65 223.10 Td (fees ) Tj ET Q q 0 0 0 rg BT 253.26 223.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 289.77 223.10 Td (from ) Tj ET Q q 0 0 0 rg BT 310.72 223.10 Td (the ) Tj ET Q q 0 0 0 rg BT 324.45 223.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 368.17 223.10 Td (of ) Tj ET Q q 0 0 0 rg BT 378.01 223.10 Td (the ) Tj ET Q q 0 0 0 rg BT 391.74 223.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 426.01 223.10 Td (and ) Tj ET Q q 0 0 0 rg BT 441.96 223.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 502.35 223.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 519.94 223.10 Td ( ) Tj ET Q q 0 0 0 rg BT 521.46 223.10 Td (medicines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 211.10 Td (businesses. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 199.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 199.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 105.92 199.10 Td (char) Tj ET Q q 0 0 0 rg BT 122.94 199.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 138.52 199.10 Td (consist ) Tj ET Q q 0 0 0 rg BT 168.55 199.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 208.01 199.10 Td (of ) Tj ET Q q 0 0 0 rg BT 218.59 199.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 261.94 199.10 Td (char) Tj ET Q q 0 0 0 rg BT 278.96 199.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 294.54 199.10 Td (due ) Tj ET Q q 0 0 0 rg BT 311.23 199.10 Td (to ) Tj ET Q q 0 0 0 rg BT 321.26 199.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.72 199.10 Td (magnitude ) Tj ET Q q 0 0 0 rg BT 380.18 199.10 Td (of ) Tj ET Q q 0 0 0 rg BT 390.76 199.10 Td (lump ) Tj ET Q q 0 0 0 rg BT 413.56 199.10 Td (sum ) Tj ET Q q 0 0 0 rg BT 432.48 199.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 473.06 199.10 Td (for ) Tj ET Q q 0 0 0 rg BT 486.97 199.10 Td (the ) Tj ET Q q 0 0 0 rg BT 501.43 199.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 539.22 199.10 Td (of ) Tj ET Q q 0 0 0 rg BT 549.80 199.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 187.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 92.28 187.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 125.89 187.10 Td (plan. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 175.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 175.10 Td (W) Tj ET Q q 0 0 0 rg BT 81.04 175.10 Td (ritten ) Tj ET Q q 0 0 0 rg BT 105.35 175.10 Td (option ) Tj ET Q q 0 0 0 rg BT 134.11 175.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 181.20 175.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 217.74 175.10 Td (income ) Tj ET Q q 0 0 0 rg BT 250.38 175.10 Td (of ) Tj ET Q q 0 0 0 rg BT 261.92 175.10 Td ($123 ) Tj ET Q q 0 0 0 rg BT 285.13 175.10 Td (million ) Tj ET Q q 0 0 0 rg BT 317.22 175.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 355.43 175.10 Td (from ) Tj ET Q q 0 0 0 rg BT 378.07 175.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.50 175.10 Td (change ) Tj ET Q q 0 0 0 rg BT 425.02 175.10 Td (in ) Tj ET Q q 0 0 0 rg BT 436.01 175.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 453.09 175.10 Td (value ) Tj ET Q q 0 0 0 rg BT 477.96 175.10 Td (of ) Tj ET Q q 0 0 0 rg BT 489.50 175.10 Td (the ) Tj ET Q q 0 0 0 rg BT 504.92 175.10 Td (written ) Tj ET Q q 0 0 0 rg BT 536.45 175.10 Td (option ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 163.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 105.61 163.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 146.43 163.10 Td (to ) Tj ET Q q 0 0 0 rg BT 156.71 163.10 Td (the ) Tj ET Q q 0 0 0 rg BT 171.42 163.10 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 202.81 163.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 236.39 163.10 Td (in ) Tj ET Q q 0 0 0 rg BT 246.67 163.10 Td (2015.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 151.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 151.10 Td (A) Tj ET Q q 0 0 0 rg BT 78.67 151.10 Td ( ) Tj ET Q q 0 0 0 rg BT 80.34 151.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 97.58 151.10 Td (on ) Tj ET Q q 0 0 0 rg BT 109.26 151.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 128.15 151.10 Td (redemption ) Tj ET Q q 0 0 0 rg BT 175.36 151.10 Td (resulted ) Tj ET Q q 0 0 0 rg BT 208.69 151.10 Td (from ) Tj ET Q q 0 0 0 rg BT 229.81 151.10 Td (the ) Tj ET Q q 0 0 0 rg BT 243.70 151.10 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 288.68 151.10 Td (of ) Tj ET Q q 0 0 0 rg BT 298.68 151.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 327.56 151.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 368.67 151.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 387.56 151.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 433.68 151.10 Td (in ) Tj ET Q q 0 0 0 rg BT 443.13 151.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 464.81 151.10 Td (and ) Tj ET Q q 0 0 0 rg BT 480.92 151.10 Td (the ) Tj ET Q q 0 0 0 rg BT 494.81 151.10 Td (early ) Tj ET Q q 0 0 0 rg BT 516.47 151.10 Td (redemption ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 139.10 Td (of ) Tj ET Q q 0 0 0 rg BT 82.83 139.10 Td (Euro ) Tj ET Q q 0 0 0 rg BT 104.77 139.10 Td (notes ) Tj ET Q q 0 0 0 rg BT 128.38 139.10 Td (and ) Tj ET Q q 0 0 0 rg BT 145.32 139.10 Td (a ) Tj ET Q q 0 0 0 rg BT 152.25 139.10 Td (tender ) Tj ET Q q 0 0 0 rg BT 179.74 139.10 Td (of) Tj ET Q q 0 0 0 rg BT 187.89 139.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 201.49 139.10 Td (for ) Tj ET Q q 0 0 0 rg BT 215.65 139.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 245.35 139.10 Td (other ) Tj ET Q q 0 0 0 rg BT 268.40 139.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 288.11 139.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 328.38 139.10 Td (in ) Tj ET Q q 0 0 0 rg BT 338.66 139.10 Td (2015.) Tj ET Q endstream endobj 83 0 obj <> endobj 84 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (41) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Income T) Tj ET Q q 0 0 0 rg BT 74.80 749.25 Td (axes) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 725.75 343.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 378.50 725.75 63.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 441.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 445.50 725.75 63.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 508.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 725.75 63.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 699.75 343.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 378.50 699.75 63.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 441.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 445.50 699.75 63.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 508.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 699.75 63.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 378.5 725.75 m 441.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 445.5 725.75 m 508.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 725.75 m 575.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 378.5 725.75 m 441.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 445.5 725.75 m 508.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 725.75 m 575.5 725.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 730.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 401.50 729.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 468.50 729.98 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 535.50 729.98 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 716.32 Td (Earnings Before Income ) Tj ET Q q 0 0 0 rg BT 138.15 716.32 Td (T) Tj ET Q q 0 0 0 rg BT 143.82 716.32 Td (axes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.00 716.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 716.32 Td (5,131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.00 716.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.15 716.32 Td (5,915) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.00 716.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.15 716.32 Td (2,077) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 703.32 Td (Provision for income taxes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.15 703.32 Td (4,156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.15 703.32 Td (1,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 551.65 703.32 Td (446) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 690.32 Td (Ef) Tj ET Q q 0 0 0 rg BT 47.26 690.32 Td (fective tax rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.15 690.32 Td (81.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.65 690.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 690.32 Td (23.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 690.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 690.32 Td (21.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 690.32 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 663.25 Td (New ) Tj ET Q q 0 0 0 rg BT 57.56 663.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 72.45 663.25 Td (reform ) Tj ET Q q 0 0 0 rg BT 102.33 663.25 Td (legislation ) Tj ET Q q 0 0 0 rg BT 146.67 663.25 Td (in ) Tj ET Q q 0 0 0 rg BT 157.12 663.25 Td (the ) Tj ET Q q 0 0 0 rg BT 172.01 663.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 192.47 663.25 Td (was ) Tj ET Q q 0 0 0 rg BT 210.69 663.25 Td (enacted ) Tj ET Q q 0 0 0 rg BT 243.90 663.25 Td (on ) Tj ET Q q 0 0 0 rg BT 256.58 663.25 Td (December ) Tj ET Q q 0 0 0 rg BT 300.33 663.25 Td (22, ) Tj ET Q q 0 0 0 rg BT 315.51 663.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 338.18 663.25 Td (known ) Tj ET Q q 0 0 0 rg BT 368.08 663.25 Td (as ) Tj ET Q q 0 0 0 rg BT 379.09 663.25 Td (the ) Tj ET Q q 0 0 0 rg BT 393.78 663.25 Td (T) Tj ET Q q 0 0 0 rg BT 399.19 663.25 Td (ax ) Tj ET Q q 0 0 0 rg BT 411.31 663.25 Td (Cuts ) Tj ET Q q 0 0 0 rg BT 432.32 663.25 Td (and ) Tj ET Q q 0 0 0 rg BT 449.44 663.25 Td (Jobs ) Tj ET Q q 0 0 0 rg BT 469.30 663.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 486.42 663.25 Td (of ) Tj ET Q q 0 0 0 rg BT 497.42 663.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 520.10 663.25 Td (\(the ) Tj ET Q q 0 0 0 rg BT 537.73 663.25 Td (Act\). ) Tj ET Q q 0 0 0 rg BT 560.48 663.25 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 651.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 52.74 651.25 Td (moves ) Tj ET Q q 0 0 0 rg BT 81.16 651.25 Td (from ) Tj ET Q q 0 0 0 rg BT 102.90 651.25 Td (a ) Tj ET Q q 0 0 0 rg BT 109.64 651.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 154.72 651.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 169.24 651.25 Td (system ) Tj ET Q q 0 0 0 rg BT 199.32 651.25 Td (to ) Tj ET Q q 0 0 0 rg BT 209.40 651.25 Td (a ) Tj ET Q q 0 0 0 rg BT 216.15 651.25 Td (quasi-territorial ) Tj ET Q q 0 0 0 rg BT 280.65 651.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 295.17 651.25 Td (system ) Tj ET Q q 0 0 0 rg BT 325.25 651.25 Td (and ) Tj ET Q q 0 0 0 rg BT 342.00 651.25 Td (comprises ) Tj ET Q q 0 0 0 rg BT 384.85 651.25 Td (broad ) Tj ET Q q 0 0 0 rg BT 409.92 651.25 Td (and ) Tj ET Q q 0 0 0 rg BT 426.66 651.25 Td (complex ) Tj ET Q q 0 0 0 rg BT 463.40 651.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 497.91 651.25 Td (to ) Tj ET Q q 0 0 0 rg BT 508.00 651.25 Td (the ) Tj ET Q q 0 0 0 rg BT 522.52 651.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 542.61 651.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 557.13 651.25 Td (code ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 639.25 Td (including, ) Tj ET Q q 0 0 0 rg BT 78.77 639.25 Td (but ) Tj ET Q q 0 0 0 rg BT 94.04 639.25 Td (not ) Tj ET Q q 0 0 0 rg BT 109.32 639.25 Td (limited ) Tj ET Q q 0 0 0 rg BT 140.14 639.25 Td (to, ) Tj ET Q q 0 0 0 rg BT 152.91 639.25 Td (\(1\) ) Tj ET Q q 0 0 0 rg BT 167.07 639.25 Td (reducing ) Tj ET Q q 0 0 0 rg BT 204.55 639.25 Td (the ) Tj ET Q q 0 0 0 rg BT 219.26 639.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 239.54 639.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 254.25 639.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 271.73 639.25 Td (from ) Tj ET Q q 0 0 0 rg BT 293.67 639.25 Td (35% ) Tj ET Q q 0 0 0 rg BT 314.49 639.25 Td (to ) Tj ET Q q 0 0 0 rg BT 324.76 639.25 Td (21%; ) Tj ET Q q 0 0 0 rg BT 348.37 639.25 Td (\(2\) ) Tj ET Q q 0 0 0 rg BT 362.52 639.25 Td (adding ) Tj ET Q q 0 0 0 rg BT 392.24 639.25 Td (a ) Tj ET Q q 0 0 0 rg BT 399.17 639.25 Td (deemed ) Tj ET Q q 0 0 0 rg BT 432.76 639.25 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 481.34 639.25 Td (transition ) Tj ET Q q 0 0 0 rg BT 521.61 639.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 536.32 639.25 Td (on ) Tj ET Q q 0 0 0 rg BT 548.82 639.25 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 627.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 67.66 627.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 104.33 627.25 Td (and ) Tj ET Q q 0 0 0 rg BT 121.55 627.25 Td (profits; ) Tj ET Q q 0 0 0 rg BT 153.23 627.25 Td (\(3\) ) Tj ET Q q 0 0 0 rg BT 167.67 627.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 207.66 627.25 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 256.00 627.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 276.57 627.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 307.11 627.25 Td (income ) Tj ET Q q 0 0 0 rg BT 339.33 627.25 Td (taxes ) Tj ET Q q 0 0 0 rg BT 362.66 627.25 Td (on ) Tj ET Q q 0 0 0 rg BT 375.45 627.25 Td (dividends ) Tj ET Q q 0 0 0 rg BT 417.13 627.25 Td (from ) Tj ET Q q 0 0 0 rg BT 439.35 627.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 471.01 627.25 Td (subsidiaries; ) Tj ET Q q 0 0 0 rg BT 523.80 627.25 Td (\(4\) ) Tj ET Q q 0 0 0 rg BT 538.24 627.25 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 615.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.10 615.25 Td (income ) Tj ET Q q 0 0 0 rg BT 98.42 615.25 Td (of ) Tj ET Q q 0 0 0 rg BT 109.65 615.25 Td (controlled ) Tj ET Q q 0 0 0 rg BT 153.08 615.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 184.85 615.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 230.51 615.25 Td (in ) Tj ET Q q 0 0 0 rg BT 241.18 615.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 261.85 615.25 Td (taxable ) Tj ET Q q 0 0 0 rg BT 293.62 615.25 Td (income; ) Tj ET Q q 0 0 0 rg BT 328.72 615.25 Td (\(5\) ) Tj ET Q q 0 0 0 rg BT 343.28 615.25 Td (creating ) Tj ET Q q 0 0 0 rg BT 378.37 615.25 Td (a ) Tj ET Q q 0 0 0 rg BT 385.70 615.25 Td (new ) Tj ET Q q 0 0 0 rg BT 405.26 615.25 Td (minimum ) Tj ET Q q 0 0 0 rg BT 447.04 615.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 462.15 615.25 Td (referred ) Tj ET Q q 0 0 0 rg BT 496.68 615.25 Td (to ) Tj ET Q q 0 0 0 rg BT 507.35 615.25 Td (as ) Tj ET Q q 0 0 0 rg BT 518.58 615.25 Td (a ) Tj ET Q q 0 0 0 rg BT 525.91 615.25 Td (base ) Tj ET Q q 0 0 0 rg BT 546.57 615.25 Td (erosion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 603.25 Td (anti-abuse ) Tj ET Q q 0 0 0 rg BT 79.59 603.25 Td (income ) Tj ET Q q 0 0 0 rg BT 111.53 603.25 Td (tax; ) Tj ET Q q 0 0 0 rg BT 129.02 603.25 Td (\(6\) ) Tj ET Q q 0 0 0 rg BT 143.18 603.25 Td (limiting ) Tj ET Q q 0 0 0 rg BT 177.35 603.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 207.05 603.25 Td (research-based ) Tj ET Q q 0 0 0 rg BT 268.96 603.25 Td (credits; ) Tj ET Q q 0 0 0 rg BT 300.89 603.25 Td (and ) Tj ET Q q 0 0 0 rg BT 317.83 603.25 Td (\(7\) ) Tj ET Q q 0 0 0 rg BT 331.99 603.25 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 380.04 603.25 Td (the ) Tj ET Q q 0 0 0 rg BT 394.75 603.25 Td (domestic ) Tj ET Q q 0 0 0 rg BT 433.36 603.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 494.17 603.25 Td (deduction.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 579.25 Td (Although ) Tj ET Q q 0 0 0 rg BT 75.94 579.25 Td (many ) Tj ET Q q 0 0 0 rg BT 100.31 579.25 Td (aspects ) Tj ET Q q 0 0 0 rg BT 131.35 579.25 Td (of ) Tj ET Q q 0 0 0 rg BT 141.84 579.25 Td (the ) Tj ET Q q 0 0 0 rg BT 155.74 579.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 172.34 579.25 Td (are ) Tj ET Q q 0 0 0 rg BT 186.71 579.25 Td (not ) Tj ET Q q 0 0 0 rg BT 201.64 579.25 Td (ef) Tj ET Q q 0 0 0 rg BT 209.23 579.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 238.59 579.25 Td (until ) Tj ET Q q 0 0 0 rg BT 259.09 579.25 Td (2018, ) Tj ET Q q 0 0 0 rg BT 283.75 579.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 325.90 579.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 340.27 579.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 374.64 579.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 385.13 579.25 Td ($2.9 ) Tj ET Q q 0 0 0 rg BT 404.79 579.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.90 579.25 Td ( ) Tj ET Q q 0 0 0 rg BT 433.06 579.25 Td (was ) Tj ET Q q 0 0 0 rg BT 450.77 579.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 496.80 579.25 Td (in ) Tj ET Q q 0 0 0 rg BT 506.73 579.25 Td (the ) Tj ET Q q 0 0 0 rg BT 521.11 579.25 Td (fourth ) Tj ET Q q 0 0 0 rg BT 547.71 579.25 Td (quarter ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 567.25 Td (of ) Tj ET Q q 0 0 0 rg BT 47.23 567.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 70.12 567.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 93.02 567.25 Td (enactment ) Tj ET Q q 0 0 0 rg BT 137.01 567.25 Td (of ) Tj ET Q q 0 0 0 rg BT 148.23 567.25 Td (the ) Tj ET Q q 0 0 0 rg BT 162.71 567.25 Td (Act. ) Tj ET Q q 0 0 0 rg BT 182.33 567.25 Td (The ) Tj ET Q q 0 0 0 rg BT 200.78 567.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 243.67 567.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 278.77 567.25 Td (increased ) Tj ET Q q 0 0 0 rg BT 319.42 567.25 Td (the ) Tj ET Q q 0 0 0 rg BT 334.53 567.25 Td (ef) Tj ET Q q 0 0 0 rg BT 342.12 567.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 372.22 567.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 387.33 567.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 405.22 567.25 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.11 567.25 Td (56.7%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.94 567.25 Td ( ) Tj ET Q q 0 0 0 rg BT 446.84 567.25 Td (and ) Tj ET Q q 0 0 0 rg BT 464.18 567.25 Td (included ) Tj ET Q q 0 0 0 rg BT 501.51 567.25 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.84 567.25 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 529.24 567.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.35 567.25 Td ( ) Tj ET Q q 0 0 0 rg BT 558.25 567.25 Td (one-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 555.25 Td (time ) Tj ET Q q 0 0 0 rg BT 56.82 555.25 Td (deemed ) Tj ET Q q 0 0 0 rg BT 90.96 555.25 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 140.10 555.25 Td (transition ) Tj ET Q q 0 0 0 rg BT 180.92 555.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 196.19 555.25 Td (on ) Tj ET Q q 0 0 0 rg BT 209.24 555.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 254.50 555.25 Td (untaxed ) Tj ET Q q 0 0 0 rg BT 289.21 555.25 Td (post-1986 ) Tj ET Q q 0 0 0 rg BT 332.25 555.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 364.18 555.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 401.10 555.25 Td (and ) Tj ET Q q 0 0 0 rg BT 418.59 555.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 447.75 555.25 Td (\(including ) Tj ET Q q 0 0 0 rg BT 491.90 555.25 Td (related ) Tj ET Q q 0 0 0 rg BT 522.15 555.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 537.42 555.25 Td (reserves\). ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 543.25 Td (Those ) Tj ET Q q 0 0 0 rg BT 63.38 543.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 100.20 543.25 Td (were ) Tj ET Q q 0 0 0 rg BT 122.57 543.25 Td (ef) Tj ET Q q 0 0 0 rg BT 130.16 543.25 Td (fectively ) Tj ET Q q 0 0 0 rg BT 168.09 543.25 Td (taxed ) Tj ET Q q 0 0 0 rg BT 192.68 543.25 Td (at ) Tj ET Q q 0 0 0 rg BT 202.84 543.25 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 210.23 543.25 Td (15.5%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 236.06 543.25 Td ( ) Tj ET Q q 0 0 0 rg BT 239.00 543.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 256.93 543.25 Td (to ) Tj ET Q q 0 0 0 rg BT 267.65 543.25 Td (the ) Tj ET Q q 0 0 0 rg BT 282.81 543.25 Td (extent ) Tj ET Q q 0 0 0 rg BT 310.19 543.25 Td (that ) Tj ET Q q 0 0 0 rg BT 328.13 543.25 Td (the ) Tj ET Q q 0 0 0 rg BT 343.29 543.25 Td (specified ) Tj ET Q q 0 0 0 rg BT 382.32 543.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 414.14 543.25 Td (corporations ) Tj ET Q q 0 0 0 rg BT 467.07 543.25 Td (held ) Tj ET Q q 0 0 0 rg BT 487.23 543.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 507.94 543.25 Td (and ) Tj ET Q q 0 0 0 rg BT 525.33 543.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 555.47 543.25 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 531.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 60.85 531.25 Td (and ) Tj ET Q q 0 0 0 rg BT 76.81 531.25 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.77 531.25 Td (8.0%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 108.60 531.25 Td ( ) Tj ET Q q 0 0 0 rg BT 110.12 531.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 126.63 531.25 Td (on ) Tj ET Q q 0 0 0 rg BT 138.15 531.25 Td (the ) Tj ET Q q 0 0 0 rg BT 151.89 531.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 193.95 531.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 229.35 531.25 Td (and ) Tj ET Q q 0 0 0 rg BT 245.31 531.25 Td (profits. ) Tj ET Q q 0 0 0 rg BT 275.33 531.25 Td (The ) Tj ET Q q 0 0 0 rg BT 292.39 531.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 334.46 531.25 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.46 531.25 Td (285 ) Tj ET Q q 0 0 0 rg BT 355.98 531.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.87 531.25 Td ( ) Tj ET Q q 0 0 0 rg BT 386.39 531.25 Td (of ) Tj ET Q q 0 0 0 rg BT 396.24 531.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 437.75 531.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 451.49 531.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 485.22 531.25 Td (included ) Tj ET Q q 0 0 0 rg BT 521.17 531.25 Td (an ) Tj ET Q q 0 0 0 rg BT 532.13 531.25 Td (adjustment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 519.25 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 519.25 Td (measure ) Tj ET Q q 0 0 0 rg BT 82.09 519.25 Td (net ) Tj ET Q q 0 0 0 rg BT 96.81 519.25 Td (deferred ) Tj ET Q q 0 0 0 rg BT 132.62 519.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 147.33 519.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 173.16 519.25 Td (at ) Tj ET Q q 0 0 0 rg BT 182.88 519.25 Td (the ) Tj ET Q q 0 0 0 rg BT 197.60 519.25 Td (new ) Tj ET Q q 0 0 0 rg BT 216.76 519.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 237.04 519.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 251.76 519.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 269.24 519.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 280.07 519.25 Td (21%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.40 519.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 495.25 Td (The ) Tj ET Q q 0 0 0 rg BT 53.90 495.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 100.12 495.25 Td (for ) Tj ET Q q 0 0 0 rg BT 114.13 495.25 Td (the ) Tj ET Q q 0 0 0 rg BT 128.70 495.25 Td (reduction ) Tj ET Q q 0 0 0 rg BT 168.81 495.25 Td (of ) Tj ET Q q 0 0 0 rg BT 179.50 495.25 Td (deferred ) Tj ET Q q 0 0 0 rg BT 215.15 495.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 229.72 495.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 255.40 495.25 Td (to ) Tj ET Q q 0 0 0 rg BT 265.53 495.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 280.10 495.25 Td (21%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.43 495.25 Td ( ) Tj ET Q q 0 0 0 rg BT 300.78 495.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 315.35 495.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 332.68 495.25 Td (is ) Tj ET Q q 0 0 0 rg BT 341.71 495.25 Td (complete. ) Tj ET Q q 0 0 0 rg BT 383.04 495.25 Td (The ) Tj ET Q q 0 0 0 rg BT 400.94 495.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 415.50 495.25 Td (char) Tj ET Q q 0 0 0 rg BT 432.53 495.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 444.32 495.25 Td (for ) Tj ET Q q 0 0 0 rg BT 458.33 495.25 Td (the ) Tj ET Q q 0 0 0 rg BT 472.90 495.25 Td (deemed ) Tj ET Q q 0 0 0 rg BT 506.34 495.25 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 554.78 495.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 569.35 495.25 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 483.25 Td (incomplete, ) Tj ET Q q 0 0 0 rg BT 84.94 483.25 Td (but ) Tj ET Q q 0 0 0 rg BT 99.73 483.25 Td (was ) Tj ET Q q 0 0 0 rg BT 117.29 483.25 Td (recorded ) Tj ET Q q 0 0 0 rg BT 154.27 483.25 Td (as ) Tj ET Q q 0 0 0 rg BT 164.61 483.25 Td (a ) Tj ET Q q 0 0 0 rg BT 171.06 483.25 Td (provisional ) Tj ET Q q 0 0 0 rg BT 218.06 483.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 250.07 483.25 Td (as ) Tj ET Q q 0 0 0 rg BT 260.41 483.25 Td (we ) Tj ET Q q 0 0 0 rg BT 274.08 483.25 Td (were ) Tj ET Q q 0 0 0 rg BT 295.51 483.25 Td (able ) Tj ET Q q 0 0 0 rg BT 314.18 483.25 Td (to ) Tj ET Q q 0 0 0 rg BT 323.97 483.25 Td (make ) Tj ET Q q 0 0 0 rg BT 347.63 483.25 Td (a ) Tj ET Q q 0 0 0 rg BT 354.08 483.25 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 398.84 483.25 Td (estimate ) Tj ET Q q 0 0 0 rg BT 434.17 483.25 Td (of ) Tj ET Q q 0 0 0 rg BT 444.51 483.25 Td (this ) Tj ET Q q 0 0 0 rg BT 460.97 483.25 Td (tax. ) Tj ET Q q 0 0 0 rg BT 477.55 483.25 Td (The ) Tj ET Q q 0 0 0 rg BT 495.11 483.25 Td (provisional ) Tj ET Q q 0 0 0 rg BT 542.11 483.25 Td (amounts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 471.25 Td (may ) Tj ET Q q 0 0 0 rg BT 55.27 471.25 Td (change ) Tj ET Q q 0 0 0 rg BT 85.64 471.25 Td (when ) Tj ET Q q 0 0 0 rg BT 109.36 471.25 Td (completed ) Tj ET Q q 0 0 0 rg BT 153.07 471.25 Td (in ) Tj ET Q q 0 0 0 rg BT 162.90 471.25 Td (2018 ) Tj ET Q q 0 0 0 rg BT 184.96 471.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 207.01 471.25 Td (finalizing ) Tj ET Q q 0 0 0 rg BT 247.39 471.25 Td (untaxed ) Tj ET Q q 0 0 0 rg BT 281.10 471.25 Td (post-1986 ) Tj ET Q q 0 0 0 rg BT 323.15 471.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 354.09 471.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 390.02 471.25 Td (and ) Tj ET Q q 0 0 0 rg BT 406.51 471.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 434.68 471.25 Td (and ) Tj ET Q q 0 0 0 rg BT 451.17 471.25 Td (related ) Tj ET Q q 0 0 0 rg BT 480.43 471.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 500.25 471.25 Td (and ) Tj ET Q q 0 0 0 rg BT 516.75 471.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 546.00 471.25 Td (eligible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 459.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 61.83 459.25 Td (of ) Tj ET Q q 0 0 0 rg BT 72.67 459.25 Td (the ) Tj ET Q q 0 0 0 rg BT 87.39 459.25 Td (specified ) Tj ET Q q 0 0 0 rg BT 125.99 459.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 157.37 459.25 Td (corporations. ) Tj ET Q q 0 0 0 rg BT 212.18 459.25 Td (The ) Tj ET Q q 0 0 0 rg BT 230.23 459.25 Td (provisional ) Tj ET Q q 0 0 0 rg BT 277.73 459.25 Td (amounts ) Tj ET Q q 0 0 0 rg BT 314.12 459.25 Td (may ) Tj ET Q q 0 0 0 rg BT 333.84 459.25 Td (also ) Tj ET Q q 0 0 0 rg BT 352.45 459.25 Td (change ) Tj ET Q q 0 0 0 rg BT 383.27 459.25 Td (if ) Tj ET Q q 0 0 0 rg BT 391.88 459.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 434.37 459.25 Td (guidance ) Tj ET Q q 0 0 0 rg BT 472.97 459.25 Td (of ) Tj ET Q q 0 0 0 rg BT 483.81 459.25 Td (the ) Tj ET Q q 0 0 0 rg BT 498.53 459.25 Td (relevant ) Tj ET Q q 0 0 0 rg BT 533.23 459.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 547.95 459.25 Td (code ) Tj ET Q q 0 0 0 rg BT 569.33 459.25 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 447.25 Td (released.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 423.25 Td (Excluding ) Tj ET Q q 0 0 0 rg BT 81.16 423.25 Td (the ) Tj ET Q q 0 0 0 rg BT 97.44 423.25 Td (above ) Tj ET Q q 0 0 0 rg BT 125.37 423.25 Td (transitional ) Tj ET Q q 0 0 0 rg BT 174.42 423.25 Td (impacts ) Tj ET Q q 0 0 0 rg BT 209.59 423.25 Td (related ) Tj ET Q q 0 0 0 rg BT 240.85 423.25 Td (to ) Tj ET Q q 0 0 0 rg BT 252.69 423.25 Td (the ) Tj ET Q q 0 0 0 rg BT 268.06 423.25 Td (Act, ) Tj ET Q q 0 0 0 rg BT 289.06 423.25 Td (the ) Tj ET Q q 0 0 0 rg BT 305.34 423.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 321.61 423.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 352.89 423.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 395.26 423.25 Td (to ) Tj ET Q q 0 0 0 rg BT 407.10 423.25 Td (non-deductible ) Tj ET Q q 0 0 0 rg BT 471.14 423.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 496.87 423.25 Td (char) Tj ET Q q 0 0 0 rg BT 513.90 423.25 Td (ges, ) Tj ET Q q 0 0 0 rg BT 533.79 423.25 Td (divestiture ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 411.25 Td (transactions ) Tj ET Q q 0 0 0 rg BT 86.21 411.25 Td (and ) Tj ET Q q 0 0 0 rg BT 103.09 411.25 Td (other ) Tj ET Q q 0 0 0 rg BT 126.08 411.25 Td (specified ) Tj ET Q q 0 0 0 rg BT 164.61 411.25 Td (items ) Tj ET Q q 0 0 0 rg BT 188.72 411.25 Td (increased ) Tj ET Q q 0 0 0 rg BT 228.92 411.25 Td (the ) Tj ET Q q 0 0 0 rg BT 243.58 411.25 Td (ef) Tj ET Q q 0 0 0 rg BT 251.17 411.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 280.81 411.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 295.47 411.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 312.90 411.25 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.34 411.25 Td (3.3%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.17 411.25 Td ( ) Tj ET Q q 0 0 0 rg BT 348.62 411.25 Td (in ) Tj ET Q q 0 0 0 rg BT 358.84 411.25 Td (2017, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.78 411.25 Td (1.8%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.61 411.25 Td ( ) Tj ET Q q 0 0 0 rg BT 407.05 411.25 Td (in ) Tj ET Q q 0 0 0 rg BT 417.27 411.25 Td (2016 ) Tj ET Q q 0 0 0 rg BT 439.72 411.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 456.60 411.25 Td (0.3%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.43 411.25 Td ( ) Tj ET Q q 0 0 0 rg BT 479.87 411.25 Td (in ) Tj ET Q q 0 0 0 rg BT 490.09 411.25 Td (2015. ) Tj ET Q q 0 0 0 rg BT 515.03 411.25 Td (No ) Tj ET Q q 0 0 0 rg BT 529.70 411.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 544.36 411.25 Td (benefits ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 399.25 Td (were ) Tj ET Q q 0 0 0 rg BT 57.67 399.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 98.23 399.25 Td (to ) Tj ET Q q 0 0 0 rg BT 108.24 399.25 Td (the ) Tj ET Q q 0 0 0 rg BT 122.70 399.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 146.61 399.25 Td (char) Tj ET Q q 0 0 0 rg BT 163.63 399.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 179.20 399.25 Td (incurred ) Tj ET Q q 0 0 0 rg BT 214.76 399.25 Td (in ) Tj ET Q q 0 0 0 rg BT 224.77 399.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 270.89 399.25 Td (with ) Tj ET Q q 0 0 0 rg BT 290.90 399.25 Td (the ) Tj ET Q q 0 0 0 rg BT 305.36 399.25 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 355.37 399.25 Td (of ) Tj ET Q q 0 0 0 rg BT 365.94 399.25 Td (IFM, ) Tj ET Q q 0 0 0 rg BT 388.46 399.25 Td (Cormorant, ) Tj ET Q q 0 0 0 rg BT 436.52 399.25 Td (Padlock, ) Tj ET Q q 0 0 0 rg BT 473.48 399.25 Td (Cardioxyl, ) Tj ET Q q 0 0 0 rg BT 518.21 399.25 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 547.12 399.25 Td (and ) Tj ET Q q 0 0 0 rg BT 563.80 399.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 387.25 Td (warrant ) Tj ET Q q 0 0 0 rg BT 68.05 387.25 Td (to ) Tj ET Q q 0 0 0 rg BT 77.34 387.25 Td (acquire ) Tj ET Q q 0 0 0 rg BT 108.27 387.25 Td (Promedior) Tj ET Q q 0 0 0 rg BT 149.94 387.25 Td (. ) Tj ET Q q 0 0 0 rg BT 153.95 387.25 Td (Lower ) Tj ET Q q 0 0 0 rg BT 181.56 387.25 Td (non-deductible ) Tj ET Q q 0 0 0 rg BT 243.05 387.25 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 280.12 387.25 Td (allocated ) Tj ET Q q 0 0 0 rg BT 317.72 387.25 Td (to ) Tj ET Q q 0 0 0 rg BT 327.01 387.25 Td (business ) Tj ET Q q 0 0 0 rg BT 362.41 387.25 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 410.03 387.25 Td (and ) Tj ET Q q 0 0 0 rg BT 425.98 387.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 453.03 387.25 Td (valuation ) Tj ET Q q 0 0 0 rg BT 491.76 387.25 Td (allowances ) Tj ET Q q 0 0 0 rg BT 537.69 387.25 Td (attributed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 375.25 Td (to ) Tj ET Q q 0 0 0 rg BT 46.42 375.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 75.70 375.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 93.90 375.25 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 152.62 375.25 Td (released ) Tj ET Q q 0 0 0 rg BT 188.01 375.25 Td (in ) Tj ET Q q 0 0 0 rg BT 198.42 375.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 221.06 375.25 Td (impacted ) Tj ET Q q 0 0 0 rg BT 260.35 375.25 Td (the ) Tj ET Q q 0 0 0 rg BT 275.20 375.25 Td (ef) Tj ET Q q 0 0 0 rg BT 282.79 375.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 312.63 375.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 327.48 375.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 345.10 375.25 Td (in ) Tj ET Q q 0 0 0 rg BT 355.52 375.25 Td (2015. ) Tj ET Q q 0 0 0 rg BT 380.65 375.25 Td (In ) Tj ET Q q 0 0 0 rg BT 391.62 375.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 429.53 375.25 Td (the ) Tj ET Q q 0 0 0 rg BT 444.38 375.25 Td (adoption ) Tj ET Q q 0 0 0 rg BT 482.02 375.25 Td (of ) Tj ET Q q 0 0 0 rg BT 492.98 375.25 Td (amended ) Tj ET Q q 0 0 0 rg BT 531.71 375.25 Td (income ) Tj ET Q q 0 0 0 rg BT 563.78 375.25 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 363.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 81.61 363.25 Td (guidance ) Tj ET Q q 0 0 0 rg BT 119.45 363.25 Td (related ) Tj ET Q q 0 0 0 rg BT 148.39 363.25 Td (to ) Tj ET Q q 0 0 0 rg BT 157.91 363.25 Td (share-based ) Tj ET Q q 0 0 0 rg BT 206.84 363.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 246.91 363.25 Td (and ) Tj ET Q q 0 0 0 rg BT 263.09 363.25 Td (the ) Tj ET Q q 0 0 0 rg BT 277.04 363.25 Td (early ) Tj ET Q q 0 0 0 rg BT 298.77 363.25 Td (adoption ) Tj ET Q q 0 0 0 rg BT 335.50 363.25 Td (of ) Tj ET Q q 0 0 0 rg BT 345.57 363.25 Td (intra-entity ) Tj ET Q q 0 0 0 rg BT 391.74 363.25 Td (transfers ) Tj ET Q q 0 0 0 rg BT 427.91 363.25 Td (of ) Tj ET Q q 0 0 0 rg BT 437.98 363.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 463.05 363.25 Td (other ) Tj ET Q q 0 0 0 rg BT 485.33 363.25 Td (than ) Tj ET Q q 0 0 0 rg BT 504.29 363.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 544.36 363.25 Td (reduced ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 351.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.20 351.25 Td (ef) Tj ET Q q 0 0 0 rg BT 58.79 351.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 88.98 351.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 104.18 351.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 122.15 351.25 Td (by ) Tj ET Q q 0 0 0 rg BT 135.13 351.25 Td (2.4% ) Tj ET Q q 0 0 0 rg BT 158.95 351.25 Td (in ) Tj ET Q q 0 0 0 rg BT 169.71 351.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 195.20 351.25 Td (Earnings ) Tj ET Q q 0 0 0 rg BT 233.73 351.25 Td (mix ) Tj ET Q q 0 0 0 rg BT 252.27 351.25 Td (between ) Tj ET Q q 0 0 0 rg BT 288.57 351.25 Td (high ) Tj ET Q q 0 0 0 rg BT 309.33 351.25 Td (and ) Tj ET Q q 0 0 0 rg BT 326.76 351.25 Td (low ) Tj ET Q q 0 0 0 rg BT 344.74 351.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 359.94 351.25 Td (jurisdictions, ) Tj ET Q q 0 0 0 rg BT 414.87 351.25 Td (domestic ) Tj ET Q q 0 0 0 rg BT 453.96 351.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 515.25 351.25 Td (deductions ) Tj ET Q q 0 0 0 rg BT 561.56 351.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 339.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 64.01 339.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 84.26 339.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 115.60 339.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 130.29 339.25 Td (credits ) Tj ET Q q 0 0 0 rg BT 159.41 339.25 Td (resulting ) Tj ET Q q 0 0 0 rg BT 196.87 339.25 Td (from ) Tj ET Q q 0 0 0 rg BT 218.77 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 233.46 339.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 262.03 339.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 283.38 339.25 Td (excise ) Tj ET Q q 0 0 0 rg BT 310.83 339.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 325.52 339.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 366.30 339.25 Td (to ) Tj ET Q q 0 0 0 rg BT 376.55 339.25 Td (most ) Tj ET Q q 0 0 0 rg BT 398.46 339.25 Td (of ) Tj ET Q q 0 0 0 rg BT 409.26 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 423.94 339.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 466.95 339.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 501.62 339.25 Td (in ) Tj ET Q q 0 0 0 rg BT 511.86 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 526.55 339.25 Td (ef) Tj ET Q q 0 0 0 rg BT 534.13 339.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 563.80 339.25 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 327.25 Td (rates.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 303.25 Td (Prior ) Tj ET Q q 0 0 0 rg BT 58.11 303.25 Td (to ) Tj ET Q q 0 0 0 rg BT 67.99 303.25 Td (the ) Tj ET Q q 0 0 0 rg BT 81.85 303.25 Td (Act, ) Tj ET Q q 0 0 0 rg BT 100.90 303.25 Td (the ) Tj ET Q q 0 0 0 rg BT 115.22 303.25 Td (ef) Tj ET Q q 0 0 0 rg BT 122.81 303.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 152.12 303.25 Td (income ) Tj ET Q q 0 0 0 rg BT 183.66 303.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 197.98 303.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 215.07 303.25 Td (was ) Tj ET Q q 0 0 0 rg BT 232.73 303.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 269.83 303.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 294.71 303.25 Td (than ) Tj ET Q q 0 0 0 rg BT 314.03 303.25 Td (the ) Tj ET Q q 0 0 0 rg BT 328.35 303.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 348.24 303.25 Td (statutory ) Tj ET Q q 0 0 0 rg BT 385.34 303.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 402.44 303.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.87 303.25 Td (35%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.20 303.25 Td ( ) Tj ET Q q 0 0 0 rg BT 433.31 303.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 472.63 303.25 Td (due ) Tj ET Q q 0 0 0 rg BT 489.18 303.25 Td (to ) Tj ET Q q 0 0 0 rg BT 499.06 303.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 535.04 303.25 Td (for ) Tj ET Q q 0 0 0 rg BT 548.81 303.25 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 291.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.31 291.25 Td (our ) Tj ET Q q 0 0 0 rg BT 61.63 291.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 121.92 291.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 165.56 291.25 Td (in ) Tj ET Q q 0 0 0 rg BT 175.32 291.25 Td (low ) Tj ET Q q 0 0 0 rg BT 192.31 291.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 206.51 291.25 Td (jurisdictions ) Tj ET Q q 0 0 0 rg BT 257.94 291.25 Td (such ) Tj ET Q q 0 0 0 rg BT 278.25 291.25 Td (as ) Tj ET Q q 0 0 0 rg BT 288.56 291.25 Td (Switzerland, ) Tj ET Q q 0 0 0 rg BT 340.81 291.25 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 371.11 291.25 Td (and ) Tj ET Q q 0 0 0 rg BT 387.53 291.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 415.63 291.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 436.50 291.25 Td (which ) Tj ET Q q 0 0 0 rg BT 462.92 291.25 Td (were ) Tj ET Q q 0 0 0 rg BT 484.33 291.25 Td (indefinitely ) Tj ET Q q 0 0 0 rg BT 532.41 291.25 Td (reinvested. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 279.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.24 279.25 Td (operates ) Tj ET Q q 0 0 0 rg BT 96.68 279.25 Td (under ) Tj ET Q q 0 0 0 rg BT 122.57 279.25 Td (a ) Tj ET Q q 0 0 0 rg BT 130.13 279.25 Td (favorable ) Tj ET Q q 0 0 0 rg BT 171.00 279.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 186.34 279.25 Td (grant ) Tj ET Q q 0 0 0 rg BT 210.00 279.25 Td (in ) Tj ET Q q 0 0 0 rg BT 220.90 279.25 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 250.13 279.25 Td (Rico ) Tj ET Q q 0 0 0 rg BT 272.14 279.25 Td (not ) Tj ET Q q 0 0 0 rg BT 288.04 279.25 Td (scheduled ) Tj ET Q q 0 0 0 rg BT 331.14 279.25 Td (to ) Tj ET Q q 0 0 0 rg BT 342.04 279.25 Td (expire ) Tj ET Q q 0 0 0 rg BT 370.15 279.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 392.70 279.25 Td (to ) Tj ET Q q 0 0 0 rg BT 403.60 279.25 Td (2023. ) Tj ET Q q 0 0 0 rg BT 428.53 279.25 Td (Although ) Tj ET Q q 0 0 0 rg BT 469.43 279.25 Td (the ) Tj ET Q q 0 0 0 rg BT 484.77 279.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 526.78 279.25 Td (continues ) Tj ET Q q 0 0 0 rg BT 568.22 279.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 267.25 Td (assess ) Tj ET Q q 0 0 0 rg BT 63.06 267.25 Td (the ) Tj ET Q q 0 0 0 rg BT 77.88 267.25 Td (broad ) Tj ET Q q 0 0 0 rg BT 103.27 267.25 Td (and ) Tj ET Q q 0 0 0 rg BT 120.32 267.25 Td (complex ) Tj ET Q q 0 0 0 rg BT 157.36 267.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 192.18 267.25 Td (to ) Tj ET Q q 0 0 0 rg BT 202.57 267.25 Td (the ) Tj ET Q q 0 0 0 rg BT 217.40 267.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 237.80 267.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 252.63 267.25 Td (code, ) Tj ET Q q 0 0 0 rg BT 276.62 267.25 Td (it ) Tj ET Q q 0 0 0 rg BT 284.78 267.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 323.49 267.25 Td (expects ) Tj ET Q q 0 0 0 rg BT 356.09 267.25 Td (no ) Tj ET Q q 0 0 0 rg BT 368.70 267.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 413.52 267.25 Td (net ) Tj ET Q q 0 0 0 rg BT 428.35 267.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 458.18 267.25 Td (of ) Tj ET Q q 0 0 0 rg BT 469.12 267.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 483.95 267.25 Td (reform ) Tj ET Q q 0 0 0 rg BT 513.77 267.25 Td (on ) Tj ET Q q 0 0 0 rg BT 526.38 267.25 Td (the ) Tj ET Q q 0 0 0 rg BT 541.21 267.25 Td (ef) Tj ET Q q 0 0 0 rg BT 548.80 267.25 Td (fective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 255.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.72 255.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 68.20 255.25 Td (in ) Tj ET Q q 0 0 0 rg BT 78.48 255.25 Td (2018. ) Tj ET Q q 0 0 0 rg BT 103.48 255.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 128.19 255.25 Td (to ) Tj ET Q q 0 0 0 rg BT 138.47 255.25 Td ("Item ) Tj ET Q q 0 0 0 rg BT 163.37 255.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 173.37 255.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 213.08 255.25 Td (Statements—Note ) Tj ET Q q 0 0 0 rg BT 288.91 255.25 Td (7. ) Tj ET Q q 0 0 0 rg BT 298.91 255.25 Td (Income ) Tj ET Q q 0 0 0 rg BT 331.21 255.25 Td (T) Tj ET Q q 0 0 0 rg BT 336.62 255.25 Td (axes" ) Tj ET Q q 0 0 0 rg BT 360.97 255.25 Td (for ) Tj ET Q q 0 0 0 rg BT 375.13 255.25 Td (further ) Tj ET Q q 0 0 0 rg BT 404.84 255.25 Td (information.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 231.25 Td (Non-GAAP) Tj ET Q q 0 0 0 rg BT 83.41 231.25 Td ( Financial Measures) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 207.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.37 207.25 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 99.55 207.25 Td ( ) Tj ET Q q 0 0 0 rg BT 102.37 207.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 140.17 207.25 Td (measures, ) Tj ET Q q 0 0 0 rg BT 182.69 207.25 Td (including ) Tj ET Q q 0 0 0 rg BT 223.28 207.25 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 268.47 207.25 Td ( ) Tj ET Q q 0 0 0 rg BT 271.28 207.25 Td (earnings ) Tj ET Q q 0 0 0 rg BT 307.98 207.25 Td (and ) Tj ET Q q 0 0 0 rg BT 325.23 207.25 Td (related ) Tj ET Q q 0 0 0 rg BT 355.25 207.25 Td (EPS ) Tj ET Q q 0 0 0 rg BT 375.30 207.25 Td (information, ) Tj ET Q q 0 0 0 rg BT 427.83 207.25 Td (are ) Tj ET Q q 0 0 0 rg BT 442.85 207.25 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 478.99 207.25 Td (to ) Tj ET Q q 0 0 0 rg BT 489.58 207.25 Td (exclude ) Tj ET Q q 0 0 0 rg BT 523.50 207.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 553.51 207.25 Td (costs, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 195.25 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 76.87 195.25 Td (gains ) Tj ET Q q 0 0 0 rg BT 100.24 195.25 Td (and ) Tj ET Q q 0 0 0 rg BT 116.95 195.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 143.11 195.25 Td (and ) Tj ET Q q 0 0 0 rg BT 159.81 195.25 Td (other ) Tj ET Q q 0 0 0 rg BT 182.63 195.25 Td (specified ) Tj ET Q q 0 0 0 rg BT 220.99 195.25 Td (items ) Tj ET Q q 0 0 0 rg BT 244.92 195.25 Td (that ) Tj ET Q q 0 0 0 rg BT 262.18 195.25 Td (are ) Tj ET Q q 0 0 0 rg BT 276.65 195.25 Td (evaluated ) Tj ET Q q 0 0 0 rg BT 317.23 195.25 Td (on ) Tj ET Q q 0 0 0 rg BT 329.50 195.25 Td (an ) Tj ET Q q 0 0 0 rg BT 341.20 195.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 384.02 195.25 Td (basis. ) Tj ET Q q 0 0 0 rg BT 408.63 195.25 Td (These ) Tj ET Q q 0 0 0 rg BT 434.77 195.25 Td (items ) Tj ET Q q 0 0 0 rg BT 458.70 195.25 Td (are ) Tj ET Q q 0 0 0 rg BT 473.18 195.25 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 508.77 195.25 Td (after ) Tj ET Q q 0 0 0 rg BT 529.35 195.25 Td (considering ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 183.25 Td (their ) Tj ET Q q 0 0 0 rg BT 56.91 183.25 Td (quantitative ) Tj ET Q q 0 0 0 rg BT 106.70 183.25 Td (and ) Tj ET Q q 0 0 0 rg BT 123.72 183.25 Td (qualitative ) Tj ET Q q 0 0 0 rg BT 168.51 183.25 Td (aspects ) Tj ET Q q 0 0 0 rg BT 199.97 183.25 Td (and ) Tj ET Q q 0 0 0 rg BT 216.99 183.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 254.56 183.25 Td (have ) Tj ET Q q 0 0 0 rg BT 276.02 183.25 Td (one ) Tj ET Q q 0 0 0 rg BT 293.05 183.25 Td (or ) Tj ET Q q 0 0 0 rg BT 303.96 183.25 Td (more ) Tj ET Q q 0 0 0 rg BT 327.09 183.25 Td (of ) Tj ET Q q 0 0 0 rg BT 338.00 183.25 Td (the ) Tj ET Q q 0 0 0 rg BT 352.80 183.25 Td (following ) Tj ET Q q 0 0 0 rg BT 394.27 183.25 Td (characteristics, ) Tj ET Q q 0 0 0 rg BT 456.54 183.25 Td (such ) Tj ET Q q 0 0 0 rg BT 477.46 183.25 Td (as ) Tj ET Q q 0 0 0 rg BT 488.37 183.25 Td (being ) Tj ET Q q 0 0 0 rg BT 513.17 183.25 Td (highly ) Tj ET Q q 0 0 0 rg BT 541.31 183.25 Td (variable, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 171.25 Td (dif) Tj ET Q q 0 0 0 rg BT 46.93 171.25 Td (ficult ) Tj ET Q q 0 0 0 rg BT 70.42 171.25 Td (to ) Tj ET Q q 0 0 0 rg BT 80.58 171.25 Td (project, ) Tj ET Q q 0 0 0 rg BT 113.23 171.25 Td (unusual ) Tj ET Q q 0 0 0 rg BT 146.72 171.25 Td (in ) Tj ET Q q 0 0 0 rg BT 156.88 171.25 Td (nature, ) Tj ET Q q 0 0 0 rg BT 186.75 171.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 231.35 171.25 Td (to ) Tj ET Q q 0 0 0 rg BT 241.51 171.25 Td (the ) Tj ET Q q 0 0 0 rg BT 256.11 171.25 Td (results ) Tj ET Q q 0 0 0 rg BT 284.60 171.25 Td (of ) Tj ET Q q 0 0 0 rg BT 295.32 171.25 Td (a ) Tj ET Q q 0 0 0 rg BT 302.14 171.25 Td (particular ) Tj ET Q q 0 0 0 rg BT 342.84 171.25 Td (period ) Tj ET Q q 0 0 0 rg BT 370.77 171.25 Td (or ) Tj ET Q q 0 0 0 rg BT 381.48 171.25 Td (not ) Tj ET Q q 0 0 0 rg BT 396.64 171.25 Td (indicative ) Tj ET Q q 0 0 0 rg BT 438.46 171.25 Td (of ) Tj ET Q q 0 0 0 rg BT 449.17 171.25 Td (future ) Tj ET Q q 0 0 0 rg BT 475.43 171.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 515.58 171.25 Td (results. ) Tj ET Q q 0 0 0 rg BT 546.57 171.25 Td (Similar ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 159.25 Td (char) Tj ET Q q 0 0 0 rg BT 53.03 159.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 69.70 159.25 Td (or ) Tj ET Q q 0 0 0 rg BT 81.36 159.25 Td (gains ) Tj ET Q q 0 0 0 rg BT 105.81 159.25 Td (were ) Tj ET Q q 0 0 0 rg BT 128.58 159.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 175.78 159.25 Td (in ) Tj ET Q q 0 0 0 rg BT 186.90 159.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 209.67 159.25 Td (periods ) Tj ET Q q 0 0 0 rg BT 242.45 159.25 Td (and ) Tj ET Q q 0 0 0 rg BT 260.23 159.25 Td (will ) Tj ET Q q 0 0 0 rg BT 279.13 159.25 Td (likely ) Tj ET Q q 0 0 0 rg BT 305.24 159.25 Td (reoccur ) Tj ET Q q 0 0 0 rg BT 338.55 159.25 Td (in ) Tj ET Q q 0 0 0 rg BT 349.67 159.25 Td (future ) Tj ET Q q 0 0 0 rg BT 376.88 159.25 Td (periods ) Tj ET Q q 0 0 0 rg BT 409.66 159.25 Td (including ) Tj ET Q q 0 0 0 rg BT 450.77 159.25 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 505.21 159.25 Td (costs, ) Tj ET Q q 0 0 0 rg BT 531.05 159.25 Td (accelerated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 147.25 Td (depreciation ) Tj ET Q q 0 0 0 rg BT 87.82 147.25 Td (and ) Tj ET Q q 0 0 0 rg BT 104.66 147.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 153.16 147.25 Td (of ) Tj ET Q q 0 0 0 rg BT 163.89 147.25 Td (property) Tj ET Q q 0 0 0 rg BT 197.11 147.25 Td (, ) Tj ET Q q 0 0 0 rg BT 202.01 147.25 Td (plant ) Tj ET Q q 0 0 0 rg BT 224.41 147.25 Td (and ) Tj ET Q q 0 0 0 rg BT 241.25 147.25 Td (equipment ) Tj ET Q q 0 0 0 rg BT 285.86 147.25 Td (and ) Tj ET Q q 0 0 0 rg BT 302.70 147.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 345.09 147.25 Td (assets, ) Tj ET Q q 0 0 0 rg BT 373.32 147.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 397.39 147.25 Td (char) Tj ET Q q 0 0 0 rg BT 414.41 147.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 430.14 147.25 Td (in ) Tj ET Q q 0 0 0 rg BT 440.32 147.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 486.59 147.25 Td (with ) Tj ET Q q 0 0 0 rg BT 506.77 147.25 Td (the ) Tj ET Q q 0 0 0 rg BT 521.39 147.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 567.67 147.25 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 135.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 75.08 135.25 Td (of ) Tj ET Q q 0 0 0 rg BT 86.39 135.25 Td (third ) Tj ET Q q 0 0 0 rg BT 108.25 135.25 Td (party ) Tj ET Q q 0 0 0 rg BT 131.78 135.25 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 179.18 135.25 Td (property ) Tj ET Q q 0 0 0 rg BT 216.03 135.25 Td (rights, ) Tj ET Q q 0 0 0 rg BT 244.29 135.25 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 289.48 135.25 Td (gains ) Tj ET Q q 0 0 0 rg BT 313.56 135.25 Td (or ) Tj ET Q q 0 0 0 rg BT 324.87 135.25 Td (losses, ) Tj ET Q q 0 0 0 rg BT 354.24 135.25 Td (pension, ) Tj ET Q q 0 0 0 rg BT 390.83 135.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 413.24 135.25 Td (and ) Tj ET Q q 0 0 0 rg BT 430.65 135.25 Td (other ) Tj ET Q q 0 0 0 rg BT 454.18 135.25 Td (contractual ) Tj ET Q q 0 0 0 rg BT 501.58 135.25 Td (settlement ) Tj ET Q q 0 0 0 rg BT 545.65 135.25 Td (char) Tj ET Q q 0 0 0 rg BT 562.68 135.25 Td (ges ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 123.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.28 123.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 73.34 123.25 Td (redemption ) Tj ET Q q 0 0 0 rg BT 121.72 123.25 Td (gains ) Tj ET Q q 0 0 0 rg BT 145.67 123.25 Td (or ) Tj ET Q q 0 0 0 rg BT 156.84 123.25 Td (losses, ) Tj ET Q q 0 0 0 rg BT 186.08 123.25 Td (among ) Tj ET Q q 0 0 0 rg BT 216.14 123.25 Td (other ) Tj ET Q q 0 0 0 rg BT 239.53 123.25 Td (items. ) Tj ET Q q 0 0 0 rg BT 266.53 123.25 Td (Deferred ) Tj ET Q q 0 0 0 rg BT 304.90 123.25 Td (and ) Tj ET Q q 0 0 0 rg BT 322.18 123.25 Td (current ) Tj ET Q q 0 0 0 rg BT 353.34 123.25 Td (income ) Tj ET Q q 0 0 0 rg BT 385.61 123.25 Td (taxes ) Tj ET Q q 0 0 0 rg BT 409.00 123.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 450.17 123.25 Td (to ) Tj ET Q q 0 0 0 rg BT 460.79 123.25 Td (these ) Tj ET Q q 0 0 0 rg BT 484.17 123.25 Td (items ) Tj ET Q q 0 0 0 rg BT 508.68 123.25 Td (are ) Tj ET Q q 0 0 0 rg BT 523.73 123.25 Td (also ) Tj ET Q q 0 0 0 rg BT 542.68 123.25 Td (adjusted ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 111.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 111.25 Td (considering ) Tj ET Q q 0 0 0 rg BT 99.32 111.25 Td (their ) Tj ET Q q 0 0 0 rg BT 120.14 111.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 163.19 111.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 192.90 111.25 Td (to ) Tj ET Q q 0 0 0 rg BT 203.18 111.25 Td (the ) Tj ET Q q 0 0 0 rg BT 217.90 111.25 Td (overall ) Tj ET Q q 0 0 0 rg BT 248.16 111.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 262.88 111.25 Td (expense, ) Tj ET Q q 0 0 0 rg BT 300.09 111.25 Td (deductibility ) Tj ET Q q 0 0 0 rg BT 353.13 111.25 Td (and ) Tj ET Q q 0 0 0 rg BT 370.07 111.25 Td (jurisdictional ) Tj ET Q q 0 0 0 rg BT 425.34 111.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 440.06 111.25 Td (rates. ) Tj ET Q endstream endobj 85 0 obj <> endobj 86 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Non-GAAP) Tj ET Q q 0 0 0 rg BT 83.41 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 85.43 749.10 Td (information ) Tj ET Q q 0 0 0 rg BT 134.67 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 143.37 749.10 Td (intended ) Tj ET Q q 0 0 0 rg BT 179.82 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 189.63 749.10 Td (portray ) Tj ET Q q 0 0 0 rg BT 220.53 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 234.77 749.10 Td (results ) Tj ET Q q 0 0 0 rg BT 262.91 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 273.26 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 288.62 749.10 Td (baseline ) Tj ET Q q 0 0 0 rg BT 323.41 749.10 Td (performance, ) Tj ET Q q 0 0 0 rg BT 378.45 749.10 Td (supplement ) Tj ET Q q 0 0 0 rg BT 426.58 749.10 Td (or ) Tj ET Q q 0 0 0 rg BT 436.94 749.10 Td (enhance ) Tj ET Q q 0 0 0 rg BT 471.72 749.10 Td (management, ) Tj ET Q q 0 0 0 rg BT 527.33 749.10 Td (analysts ) Tj ET Q q 0 0 0 rg BT 561.57 749.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (investors' ) Tj ET Q q 0 0 0 rg BT 75.34 737.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 104.53 737.10 Td (understanding ) Tj ET Q q 0 0 0 rg BT 162.61 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 172.37 737.10 Td (our ) Tj ET Q q 0 0 0 rg BT 187.13 737.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 231.88 737.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 268.29 737.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 320.24 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 336.10 737.10 Td (facilitate ) Tj ET Q q 0 0 0 rg BT 372.50 737.10 Td (comparisons ) Tj ET Q q 0 0 0 rg BT 424.48 737.10 Td (among ) Tj ET Q q 0 0 0 rg BT 453.12 737.10 Td (current, ) Tj ET Q q 0 0 0 rg BT 485.36 737.10 Td (past ) Tj ET Q q 0 0 0 rg BT 502.90 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 518.77 737.10 Td (future ) Tj ET Q q 0 0 0 rg BT 544.07 737.10 Td (periods. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (For ) Tj ET Q q 0 0 0 rg BT 52.16 725.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 90.79 725.10 Td (non-GAAP) Tj ET Q q 0 0 0 rg BT 135.98 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 138.24 725.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 174.38 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 191.09 725.10 Td (EPS ) Tj ET Q q 0 0 0 rg BT 210.58 725.10 Td (information ) Tj ET Q q 0 0 0 rg BT 260.06 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 269.00 725.10 Td (an ) Tj ET Q q 0 0 0 rg BT 280.70 725.10 Td (indication ) Tj ET Q q 0 0 0 rg BT 322.95 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 333.55 725.10 Td (our ) Tj ET Q q 0 0 0 rg BT 349.14 725.10 Td (baseline ) Tj ET Q q 0 0 0 rg BT 384.17 725.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 436.96 725.10 Td (before ) Tj ET Q q 0 0 0 rg BT 464.76 725.10 Td (items ) Tj ET Q q 0 0 0 rg BT 488.69 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 505.95 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 520.42 725.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 566.00 725.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (us ) Tj ET Q q 0 0 0 rg BT 46.84 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 56.57 713.10 Td (not ) Tj ET Q q 0 0 0 rg BT 71.30 713.10 Td (be ) Tj ET Q q 0 0 0 rg BT 82.69 713.10 Td (reflective ) Tj ET Q q 0 0 0 rg BT 122.38 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 132.66 713.10 Td (our ) Tj ET Q q 0 0 0 rg BT 147.94 713.10 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 182.67 713.10 Td (results. ) Tj ET Q q 0 0 0 rg BT 213.23 713.10 Td (In ) Tj ET Q q 0 0 0 rg BT 223.51 713.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 260.73 713.10 Td (this ) Tj ET Q q 0 0 0 rg BT 277.13 713.10 Td (information ) Tj ET Q q 0 0 0 rg BT 326.29 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 334.91 713.10 Td (among ) Tj ET Q q 0 0 0 rg BT 364.08 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 378.25 713.10 Td (primary ) Tj ET Q q 0 0 0 rg BT 411.85 713.10 Td (indicators ) Tj ET Q q 0 0 0 rg BT 453.23 713.10 Td (we ) Tj ET Q q 0 0 0 rg BT 466.84 713.10 Td (use ) Tj ET Q q 0 0 0 rg BT 482.12 713.10 Td (as ) Tj ET Q q 0 0 0 rg BT 492.40 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 498.79 713.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 520.74 713.10 Td (for ) Tj ET Q q 0 0 0 rg BT 534.35 713.10 Td (evaluating ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (performance, ) Tj ET Q q 0 0 0 rg BT 90.44 701.10 Td (allocating ) Tj ET Q q 0 0 0 rg BT 131.29 701.10 Td (resources, ) Tj ET Q q 0 0 0 rg BT 172.97 701.10 Td (setting ) Tj ET Q q 0 0 0 rg BT 201.05 701.10 Td (incentive ) Tj ET Q q 0 0 0 rg BT 239.13 701.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 296.09 701.10 Td (tar) Tj ET Q q 0 0 0 rg BT 306.45 701.10 Td (gets ) Tj ET Q q 0 0 0 rg BT 323.98 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 339.84 701.10 Td (planning ) Tj ET Q q 0 0 0 rg BT 376.25 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 392.11 701.10 Td (forecasting ) Tj ET Q q 0 0 0 rg BT 437.96 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 451.04 701.10 Td (future ) Tj ET Q q 0 0 0 rg BT 476.33 701.10 Td (periods. ) Tj ET Q q 0 0 0 rg BT 509.59 701.10 Td (This ) Tj ET Q q 0 0 0 rg BT 528.79 701.10 Td (information ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 45.17 689.10 Td (not ) Tj ET Q q 0 0 0 rg BT 60.45 689.10 Td (intended ) Tj ET Q q 0 0 0 rg BT 97.38 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 107.66 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 119.60 689.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 165.41 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 175.69 689.10 Td (isolation ) Tj ET Q q 0 0 0 rg BT 212.64 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 223.47 689.10 Td (as ) Tj ET Q q 0 0 0 rg BT 234.30 689.10 Td (a ) Tj ET Q q 0 0 0 rg BT 241.23 689.10 Td (substitute ) Tj ET Q q 0 0 0 rg BT 282.07 689.10 Td (for ) Tj ET Q q 0 0 0 rg BT 296.23 689.10 Td (net ) Tj ET Q q 0 0 0 rg BT 310.95 689.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 347.32 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 358.15 689.10 Td (diluted ) Tj ET Q q 0 0 0 rg BT 388.43 689.10 Td (EPS ) Tj ET Q q 0 0 0 rg BT 408.16 689.10 Td (prepared ) Tj ET Q q 0 0 0 rg BT 445.63 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 455.91 689.10 Td (accordance ) Tj ET Q q 0 0 0 rg BT 503.37 689.10 Td (with ) Tj ET Q q 0 0 0 rg BT 523.65 689.10 Td (GAAP) Tj ET Q q 0 0 0 rg BT 549.77 689.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (Specified items were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 630.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 630.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 630.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 630.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 630.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 630.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 630.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 606.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 606.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 606.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 606.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 606.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 606.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 606.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 586.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 586.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 586.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 586.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 586.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 586.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 586.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 566.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 566.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 566.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 566.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 566.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 566.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 566.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 542.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 542.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 542.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 542.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 542.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 542.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 542.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 518.60 321.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 518.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 518.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 518.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 518.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 518.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 518.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 498.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 498.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 498.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 498.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 498.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 498.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 498.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 474.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 474.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 474.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 474.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 474.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 474.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 474.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 450.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 450.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 450.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 450.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 450.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 450.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 450.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 426.60 321.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 426.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 426.60 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 426.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 426.60 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 426.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 426.60 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 399.60 321.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 399.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 399.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 399.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 399.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 399.60 4.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 399.60 69.00 -8.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 379.60 321.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 379.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 379.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 379.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 379.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 379.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 379.60 69.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 355.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 355.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 355.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 355.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 355.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 355.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 355.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 329.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 329.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 329.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 329.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 303.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 303.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 303.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 303.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 303.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 303.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 303.60 69.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 642.6 m 430.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 642.6 m 434.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 642.6 m 503.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 503.5 642.6 m 507.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 642.6 m 576.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 630.6 m 430.5 630.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 642.6 m 503.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 630.6 m 503.5 630.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 503.5 642.6 m 507.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 642.6 m 576.5 642.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 630.6 m 576.5 630.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 606.6 m 430.5 606.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 606.6 m 503.5 606.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 606.6 m 576.5 606.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 530.6 m 430.5 530.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 530.6 m 503.5 530.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 530.6 m 576.5 530.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 411.6 m 430.5 411.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 411.6 m 503.5 411.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 411.6 m 576.5 411.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 342.6 m 430.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 342.6 m 434.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 342.6 m 503.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 503.5 342.6 m 507.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 342.6 m 576.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 342.6 m 430.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 342.6 m 503.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 342.6 m 576.5 342.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 290.6 m 430.5 290.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 290.6 m 503.5 290.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 290.6 m 576.5 290.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 279.6 m 430.5 279.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 277.6 m 430.5 277.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 279.6 m 503.5 279.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 277.6 m 503.5 277.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 279.6 m 576.5 279.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 277.6 m 576.5 277.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 646.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 424.20 646.68 Td (Y) Tj ET Q q 0 0 0 rg BT 429.53 646.68 Td (ear) Tj ET Q q 0 0 0 rg BT 440.12 646.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 500.85 646.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 634.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.50 634.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 460.50 634.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.50 634.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 621.22 Td (Impairment char) Tj ET Q q 0 0 0 rg BT 105.27 621.22 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 621.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 621.22 Td (146) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 621.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 621.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 621.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 621.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 609.22 Td (Accelerated depreciation and other shutdown costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 609.22 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 609.22 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 609.22 Td (84) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 597.33 Td (Cost of pr) Tj ET Q q 0 0 0 rg BT 81.68 597.33 Td (oducts sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 597.22 Td (149) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 597.22 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 597.22 Td (84) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 577.33 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 577.22 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 577.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 577.22 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 557.22 Td (License and asset acquisition char) Tj ET Q q 0 0 0 rg BT 174.97 557.22 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 557.22 Td (1,130) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 557.22 Td (439) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 557.22 Td (1,679) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 545.22 Td (IPRD impairments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 545.22 Td (75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 545.22 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 545.22 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 533.22 Td (Site exit costs and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 533.22 Td (383) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 533.22 Td (83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 533.22 Td (44) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 521.33 Td (Resear) Tj ET Q q 0 0 0 rg BT 68.34 521.33 Td (ch and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 521.22 Td (1,588) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 521.22 Td (535) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 521.22 Td (1,883) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 501.22 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 501.22 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 501.22 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 501.22 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 501.22 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 489.22 Td (Litigation and other settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.30 489.22 Td (\(481) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 489.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 489.22 Td (40) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 489.22 Td (158) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 477.22 Td (Divestiture gains) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.30 477.22 Td (\(126) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 477.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.30 477.22 Td (\(559) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 477.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 477.22 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 477.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 465.22 Td (Royalties and licensing income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.30 465.22 Td (\(497) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 465.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.30 465.22 Td (\(10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 465.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 465.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 453.22 Td (Pension char) Tj ET Q q 0 0 0 rg BT 90.29 453.22 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 453.22 Td (162) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 453.22 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 453.22 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 441.22 Td (Intangible asset impairment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 441.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 441.22 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 441.22 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 429.22 Td (W) Tj ET Q q 0 0 0 rg BT 48.24 429.22 Td (ritten option adjustment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 429.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 429.22 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 429.22 Td (\(123) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 429.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 417.17 Td (Loss on debt redemption) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 416.27 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 416.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 416.27 Td (180) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 402.33 Td (Other) Tj ET Q q 0 0 0 rg BT 64.46 402.33 Td ( income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.30 402.22 Td (\(540) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 402.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.30 402.22 Td (\(314) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 402.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 402.22 Td (316) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 382.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.24 382.33 Td (ease to pr) Tj ET Q q 0 0 0 rg BT 98.16 382.33 Td (etax income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 382.22 Td (1,198) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 382.22 Td (242) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 382.22 Td (2,293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 358.22 Td (Income taxes on items above) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.30 358.22 Td (\(87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 358.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 358.22 Td (51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 358.22 Td (\(480) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 358.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 346.17 Td (Income taxes attributed to U.S. tax reform) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 346.17 Td (2,91) Tj ET Q q 0 0 0 rg BT 421.65 346.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 346.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 346.17 Td (—) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 333.33 Td (Income taxes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 333.17 Td (2,824) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 333.17 Td (51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 333.17 Td (\(480) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 333.17 Td (\)) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 307.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.24 307.33 Td (ease to net earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 307.17 Td (4,022) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 307.17 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 307.17 Td (1,813) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 294.17 Td (Noncontrolling interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.30 294.22 Td (\(59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 294.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 294.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 294.17 Td (—) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 281.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.15 281.33 Td (ease to net earnings used for) Tj ET Q q 0 0 0 rg BT 177.79 281.33 Td ( Diluted Non-GAAP) Tj ET Q q 0 0 0 rg BT 263.35 281.33 Td ( EPS calculation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 281.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 281.22 Td (3,963) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 281.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 281.22 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 281.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 281.22 Td (1,813) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 255.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 255.10 Td (reconciliations ) Tj ET Q q 0 0 0 rg BT 115.41 255.10 Td (from ) Tj ET Q q 0 0 0 rg BT 137.35 255.10 Td (GAAP) Tj ET Q q 0 0 0 rg BT 164.21 255.10 Td ( ) Tj ET Q q 0 0 0 rg BT 166.71 255.10 Td (to ) Tj ET Q q 0 0 0 rg BT 176.99 255.10 Td (Non-GAAP) Tj ET Q q 0 0 0 rg BT 224.39 255.10 Td ( ) Tj ET Q q 0 0 0 rg BT 226.89 255.10 Td (were ) Tj ET Q q 0 0 0 rg BT 248.82 255.10 Td (as ) Tj ET Q q 0 0 0 rg BT 259.65 255.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 220.60 351.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 220.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 391.50 220.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 220.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 220.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 513.50 220.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 220.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 192.60 351.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 192.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 391.50 192.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 192.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 192.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 513.50 192.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 192.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 164.60 351.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 164.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 391.50 164.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 164.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 164.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 513.50 164.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 164.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 136.60 351.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 136.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 391.50 136.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 136.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 136.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 513.50 136.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 136.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 108.60 351.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 108.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 391.50 108.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 108.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 108.60 59.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 513.50 108.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 108.60 59.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 232.60000000000002 m 450.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 232.60000000000002 m 454.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 232.60000000000002 m 513.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 513.5 232.60000000000002 m 517.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 232.60000000000002 m 576.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 220.60000000000002 m 450.5 220.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 232.60000000000002 m 513.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 220.60000000000002 m 513.5 220.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 513.5 232.60000000000002 m 517.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 232.60000000000002 m 576.5 232.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 220.60000000000002 m 576.5 220.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 192.60000000000002 m 450.5 192.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 192.60000000000002 m 513.5 192.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 192.60000000000002 m 576.5 192.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 179.60000000000002 m 450.5 179.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 177.60000000000002 m 450.5 177.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 179.60000000000002 m 513.5 179.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 177.60000000000002 m 513.5 177.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 179.60000000000002 m 576.5 179.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 177.60000000000002 m 576.5 177.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 108.60000000000002 m 450.5 108.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 108.60000000000002 m 513.5 108.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 108.60000000000002 m 576.5 108.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 108.60000000000002 m 450.5 108.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 95.60000000000002 m 450.5 95.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 391.5 93.60000000000002 m 450.5 93.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 108.60000000000002 m 513.5 108.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 95.60000000000002 m 513.5 95.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 454.5 93.60000000000002 m 513.5 93.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 95.60000000000002 m 576.5 95.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 93.60000000000002 m 576.5 93.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 236.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 439.20 236.68 Td (Y) Tj ET Q q 0 0 0 rg BT 444.53 236.68 Td (ear) Tj ET Q q 0 0 0 rg BT 455.12 236.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 515.85 236.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 224.55 Td (Dollars in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 412.50 224.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 475.50 224.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.50 224.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 211.17 Td (Net Earnings ) Tj ET Q q 0 0 0 rg BT 93.71 211.17 Td (Attributable to BMS used for Diluted EPS Calculation — GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.00 211.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.15 211.17 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.00 211.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.15 211.17 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.00 211.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 211.17 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 197.17 Td (Specified Items) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.15 197.17 Td (3,963) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 197.17 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 197.17 Td (1,813) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 183.17 Td (Net Earnings ) Tj ET Q q 0 0 0 rg BT 93.71 183.17 Td (Attributable to BMS used for Diluted EPS Calculation — Non-GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.00 183.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.15 183.17 Td (4,970) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.00 183.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.15 183.17 Td (4,750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.00 183.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 183.17 Td (3,378) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 155.17 Td (A) Tj ET Q q 0 0 0 rg BT 45.85 155.17 Td (verage Common Shares Outstanding — Diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.15 155.17 Td (1,652) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.15 155.17 Td (1,680) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 155.17 Td (1,679) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 127.17 Td (Diluted EPS ) Tj ET Q q 0 0 0 rg BT 90.95 127.17 Td (Attributable to BMS — GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.00 127.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.15 127.17 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.00 127.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.15 127.17 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.00 127.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 127.17 Td (0.93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 113.17 Td (Diluted EPS ) Tj ET Q q 0 0 0 rg BT 90.95 113.17 Td (Attributable to Specified Items) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.15 113.17 Td (2.40) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.15 113.17 Td (0.18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 113.17 Td (1.08) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 99.17 Td (Diluted EPS ) Tj ET Q q 0 0 0 rg BT 90.67 99.17 Td (Attributable to BMS — Non-GAAP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.00 99.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.15 99.17 Td (3.01) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.00 99.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.15 99.17 Td (2.83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.00 99.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 99.17 Td (2.01) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 87 0 obj <> endobj 88 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (43) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Financial Position, Liquidity and Capital Resour) Tj ET Q q 0 0 0 rg BT 243.64 749.25 Td (ces) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (Our net cash position was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 701.75 375.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 701.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 415.50 701.75 78.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 701.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 701.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 675.75 375.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 675.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 415.50 675.75 78.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 675.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 675.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 649.75 375.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 415.50 649.75 78.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 649.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 649.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 623.75 375.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 415.50 623.75 78.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 623.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 623.75 79.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 701.75 m 493.5 701.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 701.75 m 576.5 701.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 701.75 m 493.5 701.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 701.75 m 576.5 701.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 662.75 m 493.5 662.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 662.75 m 576.5 662.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 623.75 m 493.5 623.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 623.75 m 576.5 623.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 611.75 m 493.5 611.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 415.5 609.75 m 493.5 609.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 611.75 m 576.5 611.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 609.75 m 576.5 609.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 706.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 446.00 705.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.50 705.98 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 692.32 Td (Cash and cash equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.00 692.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 692.32 Td (5,421) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 692.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 692.32 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 679.32 Td (Marketable securities — current) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 679.32 Td (1,391) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 679.32 Td (2,1) Tj ET Q q 0 0 0 rg BT 562.65 679.32 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 666.32 Td (Marketable securities — non-current) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 666.32 Td (2,480) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 666.32 Td (2,719) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 653.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 653.32 Td (otal cash, cash equivalents and marketable securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 653.32 Td (9,292) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 653.32 Td (9,069) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 640.32 Td (Short-term debt obligations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 640.37 Td (\(987) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 640.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 640.32 Td (\(992) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 640.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 627.32 Td (Long-term debt) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 463.80 627.37 Td (\(6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 627.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 627.32 Td (\(5,716) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 627.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 614.32 Td (Net cash position) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.00 614.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 614.32 Td (1,330) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 614.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 614.32 Td (2,361) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 587.25 Td (Cash, ) Tj ET Q q 0 0 0 rg BT 61.37 587.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 82.01 587.25 Td (equivalents ) Tj ET Q q 0 0 0 rg BT 130.42 587.25 Td (and ) Tj ET Q q 0 0 0 rg BT 147.72 587.25 Td (marketable ) Tj ET Q q 0 0 0 rg BT 195.01 587.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 235.64 587.25 Td (held ) Tj ET Q q 0 0 0 rg BT 255.73 587.25 Td (in ) Tj ET Q q 0 0 0 rg BT 266.38 587.25 Td (the ) Tj ET Q q 0 0 0 rg BT 281.46 587.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 302.11 587.25 Td (were ) Tj ET Q q 0 0 0 rg BT 324.41 587.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 385.04 587.25 Td ($4.1 ) Tj ET Q q 0 0 0 rg BT 405.41 587.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.52 587.25 Td ( ) Tj ET Q q 0 0 0 rg BT 434.39 587.25 Td (at ) Tj ET Q q 0 0 0 rg BT 444.47 587.25 Td (December ) Tj ET Q q 0 0 0 rg BT 488.43 587.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 503.80 587.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 529.16 587.25 Td (Most ) Tj ET Q q 0 0 0 rg BT 552.59 587.25 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 587.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 575.25 Td (remaining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 78.71 575.25 Td ($5.2 ) Tj ET Q q 0 0 0 rg BT 98.38 575.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 124.49 575.25 Td ( ) Tj ET Q q 0 0 0 rg BT 126.66 575.25 Td (is ) Tj ET Q q 0 0 0 rg BT 135.50 575.25 Td (held ) Tj ET Q q 0 0 0 rg BT 154.88 575.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 194.26 575.25 Td (in ) Tj ET Q q 0 0 0 rg BT 204.21 575.25 Td (low-tax ) Tj ET Q q 0 0 0 rg BT 236.92 575.25 Td (jurisdictions ) Tj ET Q q 0 0 0 rg BT 288.53 575.25 Td (and ) Tj ET Q q 0 0 0 rg BT 305.14 575.25 Td (is ) Tj ET Q q 0 0 0 rg BT 313.98 575.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 344.47 575.25 Td (to ) Tj ET Q q 0 0 0 rg BT 354.42 575.25 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 401.02 575.25 Td (or ) Tj ET Q q 0 0 0 rg BT 411.52 575.25 Td (withholding ) Tj ET Q q 0 0 0 rg BT 462.02 575.25 Td (taxes ) Tj ET Q q 0 0 0 rg BT 484.74 575.25 Td (in ) Tj ET Q q 0 0 0 rg BT 494.68 575.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 524.05 575.25 Td (jurisdictions. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 563.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 563.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.54 563.25 Td (are ) Tj ET Q q 0 0 0 rg BT 66.20 563.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 96.99 563.25 Td (to ) Tj ET Q q 0 0 0 rg BT 107.23 563.25 Td (a ) Tj ET Q q 0 0 0 rg BT 114.13 563.25 Td (one-time ) Tj ET Q q 0 0 0 rg BT 152.13 563.25 Td (deemed ) Tj ET Q q 0 0 0 rg BT 185.68 563.25 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 234.23 563.25 Td (transition ) Tj ET Q q 0 0 0 rg BT 274.46 563.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 289.14 563.25 Td (of ) Tj ET Q q 0 0 0 rg BT 299.93 563.25 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 319.89 563.25 Td (billion ) Tj ET Q q 0 0 0 rg BT 348.46 563.25 Td (which ) Tj ET Q q 0 0 0 rg BT 375.36 563.25 Td (will ) Tj ET Q q 0 0 0 rg BT 393.38 563.25 Td (be ) Tj ET Q q 0 0 0 rg BT 405.28 563.25 Td (payable ) Tj ET Q q 0 0 0 rg BT 438.83 563.25 Td (over ) Tj ET Q q 0 0 0 rg BT 459.06 563.25 Td (eight ) Tj ET Q q 0 0 0 rg BT 481.51 563.25 Td (years ) Tj ET Q q 0 0 0 rg BT 505.07 563.25 Td (as ) Tj ET Q q 0 0 0 rg BT 515.86 563.25 Td (a ) Tj ET Q q 0 0 0 rg BT 522.76 563.25 Td (result ) Tj ET Q q 0 0 0 rg BT 547.44 563.25 Td (of ) Tj ET Q q 0 0 0 rg BT 558.23 563.25 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 551.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.51 551.25 Td (reform. ) Tj ET Q q 0 0 0 rg BT 82.51 551.25 Td (However) Tj ET Q q 0 0 0 rg BT 118.76 551.25 Td (, ) Tj ET Q q 0 0 0 rg BT 123.55 551.25 Td (we ) Tj ET Q q 0 0 0 rg BT 137.50 551.25 Td (expect ) Tj ET Q q 0 0 0 rg BT 165.89 551.25 Td (to ) Tj ET Q q 0 0 0 rg BT 175.96 551.25 Td (have ) Tj ET Q q 0 0 0 rg BT 197.12 551.25 Td (more ) Tj ET Q q 0 0 0 rg BT 219.96 551.25 Td (flexibility ) Tj ET Q q 0 0 0 rg BT 261.69 551.25 Td (in ) Tj ET Q q 0 0 0 rg BT 271.76 551.25 Td (accessing ) Tj ET Q q 0 0 0 rg BT 312.37 551.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 332.43 551.25 Td (and ) Tj ET Q q 0 0 0 rg BT 349.16 551.25 Td (future ) Tj ET Q q 0 0 0 rg BT 375.33 551.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 395.39 551.25 Td (that ) Tj ET Q q 0 0 0 rg BT 412.67 551.25 Td (may ) Tj ET Q q 0 0 0 rg BT 432.18 551.25 Td (be ) Tj ET Q q 0 0 0 rg BT 443.91 551.25 Td (generated ) Tj ET Q q 0 0 0 rg BT 485.07 551.25 Td (in ) Tj ET Q q 0 0 0 rg BT 495.14 551.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 526.30 551.25 Td (subsidiaries. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 539.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 539.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.37 539.25 Td (believe ) Tj ET Q q 0 0 0 rg BT 82.54 539.25 Td (that ) Tj ET Q q 0 0 0 rg BT 99.83 539.25 Td (our ) Tj ET Q q 0 0 0 rg BT 115.45 539.25 Td (existing ) Tj ET Q q 0 0 0 rg BT 149.41 539.25 Td (cash, ) Tj ET Q q 0 0 0 rg BT 171.97 539.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 192.03 539.25 Td (equivalents ) Tj ET Q q 0 0 0 rg BT 239.87 539.25 Td (and ) Tj ET Q q 0 0 0 rg BT 256.60 539.25 Td (marketable ) Tj ET Q q 0 0 0 rg BT 303.31 539.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 343.37 539.25 Td (together ) Tj ET Q q 0 0 0 rg BT 378.43 539.25 Td (with ) Tj ET Q q 0 0 0 rg BT 398.50 539.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 418.56 539.25 Td (generated ) Tj ET Q q 0 0 0 rg BT 459.72 539.25 Td (from ) Tj ET Q q 0 0 0 rg BT 481.45 539.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 525.40 539.25 Td (and ) Tj ET Q q 0 0 0 rg BT 542.13 539.25 Td (issuance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 527.25 Td (of ) Tj ET Q q 0 0 0 rg BT 47.67 527.25 Td (commercial ) Tj ET Q q 0 0 0 rg BT 98.20 527.25 Td (paper ) Tj ET Q q 0 0 0 rg BT 123.74 527.25 Td (in ) Tj ET Q q 0 0 0 rg BT 134.86 527.25 Td (the ) Tj ET Q q 0 0 0 rg BT 150.41 527.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 171.53 527.25 Td (will ) Tj ET Q q 0 0 0 rg BT 190.42 527.25 Td (be ) Tj ET Q q 0 0 0 rg BT 203.20 527.25 Td (suf) Tj ET Q q 0 0 0 rg BT 215.24 527.25 Td (ficient ) Tj ET Q q 0 0 0 rg BT 244.12 527.25 Td (to ) Tj ET Q q 0 0 0 rg BT 255.23 527.25 Td (satisfy ) Tj ET Q q 0 0 0 rg BT 284.68 527.25 Td (our ) Tj ET Q q 0 0 0 rg BT 301.34 527.25 Td (normal ) Tj ET Q q 0 0 0 rg BT 333.01 527.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 354.11 527.25 Td (requirements ) Tj ET Q q 0 0 0 rg BT 409.65 527.25 Td (for ) Tj ET Q q 0 0 0 rg BT 424.65 527.25 Td (at ) Tj ET Q q 0 0 0 rg BT 435.20 527.25 Td (least ) Tj ET Q q 0 0 0 rg BT 456.86 527.25 Td (the ) Tj ET Q q 0 0 0 rg BT 472.41 527.25 Td (next ) Tj ET Q q 0 0 0 rg BT 492.97 527.25 Td (few ) Tj ET Q q 0 0 0 rg BT 511.29 527.25 Td (years, ) Tj ET Q q 0 0 0 rg BT 538.23 527.25 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 515.25 Td (dividends, ) Tj ET Q q 0 0 0 rg BT 79.19 515.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 107.65 515.25 Td (expenditures, ) Tj ET Q q 0 0 0 rg BT 163.05 515.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 203.74 515.25 Td (payments, ) Tj ET Q q 0 0 0 rg BT 246.37 515.25 Td (working ) Tj ET Q q 0 0 0 rg BT 281.51 515.25 Td (capital, ) Tj ET Q q 0 0 0 rg BT 312.46 515.25 Td (deemed ) Tj ET Q q 0 0 0 rg BT 345.37 515.25 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 393.26 515.25 Td (transition ) Tj ET Q q 0 0 0 rg BT 432.84 515.25 Td (tax ) Tj ET Q q 0 0 0 rg BT 446.86 515.25 Td (and ) Tj ET Q q 0 0 0 rg BT 463.11 515.25 Td (maturities ) Tj ET Q q 0 0 0 rg BT 504.91 515.25 Td (of ) Tj ET Q q 0 0 0 rg BT 515.04 515.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 556.28 515.25 Td (debt.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 491.25 Td (Management ) Tj ET Q q 0 0 0 rg BT 90.50 491.25 Td (continuously ) Tj ET Q q 0 0 0 rg BT 144.46 491.25 Td (evaluates ) Tj ET Q q 0 0 0 rg BT 183.96 491.25 Td (the ) Tj ET Q q 0 0 0 rg BT 198.47 491.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 240.14 491.25 Td (s ) Tj ET Q q 0 0 0 rg BT 246.32 491.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 275.27 491.25 Td (structure ) Tj ET Q q 0 0 0 rg BT 312.55 491.25 Td (to ) Tj ET Q q 0 0 0 rg BT 322.63 491.25 Td (ensure ) Tj ET Q q 0 0 0 rg BT 351.02 491.25 Td (the ) Tj ET Q q 0 0 0 rg BT 365.54 491.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 406.72 491.25 Td (is ) Tj ET Q q 0 0 0 rg BT 415.69 491.25 Td (financed ) Tj ET Q q 0 0 0 rg BT 452.41 491.25 Td (ef) Tj ET Q q 0 0 0 rg BT 459.99 491.25 Td (ficiently) Tj ET Q q 0 0 0 rg BT 492.66 491.25 Td (, ) Tj ET Q q 0 0 0 rg BT 497.46 491.25 Td (which ) Tj ET Q q 0 0 0 rg BT 524.20 491.25 Td (may ) Tj ET Q q 0 0 0 rg BT 543.71 491.25 Td (result ) Tj ET Q q 0 0 0 rg BT 568.22 491.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 479.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.10 479.25 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 97.29 479.25 Td (of ) Tj ET Q q 0 0 0 rg BT 108.50 479.25 Td (common ) Tj ET Q q 0 0 0 rg BT 146.38 479.25 Td (stock ) Tj ET Q q 0 0 0 rg BT 170.37 479.25 Td (and ) Tj ET Q q 0 0 0 rg BT 187.69 479.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 207.79 479.25 Td (securities, ) Tj ET Q q 0 0 0 rg BT 250.94 479.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 299.92 479.25 Td (of ) Tj ET Q q 0 0 0 rg BT 311.14 479.25 Td (interest ) Tj ET Q q 0 0 0 rg BT 343.45 479.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 361.32 479.25 Td (swap ) Tj ET Q q 0 0 0 rg BT 384.76 479.25 Td (contracts ) Tj ET Q q 0 0 0 rg BT 423.73 479.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 446.06 479.25 Td (to ) Tj ET Q q 0 0 0 rg BT 456.72 479.25 Td (maturity ) Tj ET Q q 0 0 0 rg BT 493.48 479.25 Td (and ) Tj ET Q q 0 0 0 rg BT 510.80 479.25 Td (issuance ) Tj ET Q q 0 0 0 rg BT 547.56 479.25 Td (of ) Tj ET Q q 0 0 0 rg BT 558.78 479.25 Td (debt ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 467.25 Td (securities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 443.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.17 443.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 95.68 443.25 Td (repurchased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 146.61 443.25 Td ($2.5 ) Tj ET Q q 0 0 0 rg BT 166.74 443.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 192.85 443.25 Td ( ) Tj ET Q q 0 0 0 rg BT 195.48 443.25 Td (of ) Tj ET Q q 0 0 0 rg BT 206.43 443.25 Td (common ) Tj ET Q q 0 0 0 rg BT 244.05 443.25 Td (stock ) Tj ET Q q 0 0 0 rg BT 267.78 443.25 Td (in ) Tj ET Q q 0 0 0 rg BT 278.19 443.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 300.81 443.25 Td (through ) Tj ET Q q 0 0 0 rg BT 334.54 443.25 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 382.12 443.25 Td (share ) Tj ET Q q 0 0 0 rg BT 405.85 443.25 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 451.78 443.25 Td (agreements, ) Tj ET Q q 0 0 0 rg BT 502.43 443.25 Td (Rule ) Tj ET Q q 0 0 0 rg BT 523.94 443.25 Td (10b5-1 ) Tj ET Q q 0 0 0 rg BT 554.90 443.25 Td (plans ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 431.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.26 431.25 Td (open ) Tj ET Q q 0 0 0 rg BT 75.52 431.25 Td (market ) Tj ET Q q 0 0 0 rg BT 106.10 431.25 Td (purchases. ) Tj ET Q q 0 0 0 rg BT 150.65 431.25 Td (The ) Tj ET Q q 0 0 0 rg BT 169.02 431.25 Td (stock ) Tj ET Q q 0 0 0 rg BT 192.95 431.25 Td (repurchases ) Tj ET Q q 0 0 0 rg BT 242.97 431.25 Td (were ) Tj ET Q q 0 0 0 rg BT 265.22 431.25 Td (funded ) Tj ET Q q 0 0 0 rg BT 295.81 431.25 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 308.63 431.25 Td ($1.5 ) Tj ET Q q 0 0 0 rg BT 328.95 431.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 355.06 431.25 Td ( ) Tj ET Q q 0 0 0 rg BT 357.88 431.25 Td (of ) Tj ET Q q 0 0 0 rg BT 369.04 431.25 Td (new ) Tj ET Q q 0 0 0 rg BT 388.52 431.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 430.77 431.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 450.81 431.25 Td (and ) Tj ET Q q 0 0 0 rg BT 468.07 431.25 Td (cash. ) Tj ET Q q 0 0 0 rg BT 490.96 431.25 Td (The ) Tj ET Q q 0 0 0 rg BT 509.32 431.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 551.03 431.25 Td (repaid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 419.25 Td ($750 ) Tj ET Q q 0 0 0 rg BT 57.75 419.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 86.64 419.25 Td ( ) Tj ET Q q 0 0 0 rg BT 88.40 419.25 Td (of ) Tj ET Q q 0 0 0 rg BT 98.48 419.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 139.66 419.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 158.63 419.25 Td (at ) Tj ET Q q 0 0 0 rg BT 167.60 419.25 Td (maturity ) Tj ET Q q 0 0 0 rg BT 203.23 419.25 Td (and ) Tj ET Q q 0 0 0 rg BT 219.42 419.25 Td (repurchased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.48 419.25 Td ($337 ) Tj ET Q q 0 0 0 rg BT 291.23 419.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.13 419.25 Td ( ) Tj ET Q q 0 0 0 rg BT 321.88 419.25 Td (of ) Tj ET Q q 0 0 0 rg BT 331.96 419.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 373.15 419.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 392.11 419.25 Td (in ) Tj ET Q q 0 0 0 rg BT 401.64 419.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 425.90 419.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 449.86 419.25 Td (to ) Tj ET Q q 0 0 0 rg BT 459.39 419.25 Td (“Item ) Tj ET Q q 0 0 0 rg BT 483.90 419.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 493.15 419.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 532.12 419.25 Td (Statements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 407.25 Td (—Note ) Tj ET Q q 0 0 0 rg BT 67.94 407.25 Td (9. ) Tj ET Q q 0 0 0 rg BT 77.94 407.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 117.65 407.25 Td (Instruments ) Tj ET Q q 0 0 0 rg BT 167.37 407.25 Td (and ) Tj ET Q q 0 0 0 rg BT 184.31 407.25 Td (Fair ) Tj ET Q q 0 0 0 rg BT 202.73 407.25 Td (V) Tj ET Q q 0 0 0 rg BT 208.85 407.25 Td (alue ) Tj ET Q q 0 0 0 rg BT 228.00 407.25 Td (Measurements ) Tj ET Q q 0 0 0 rg BT 288.82 407.25 Td (and ) Tj ET Q q 0 0 0 rg BT 305.76 407.25 Td (Note ) Tj ET Q q 0 0 0 rg BT 327.69 407.25 Td (15. ) Tj ET Q q 0 0 0 rg BT 342.69 407.25 Td (Equity" ) Tj ET Q q 0 0 0 rg BT 375.94 407.25 Td (for ) Tj ET Q q 0 0 0 rg BT 390.10 407.25 Td (further ) Tj ET Q q 0 0 0 rg BT 419.81 407.25 Td (information. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 383.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 383.25 Td (e ) Tj ET Q q 0 0 0 rg BT 51.59 383.25 Td (issued ) Tj ET Q q 0 0 0 rg BT 79.11 383.25 Td (commercial ) Tj ET Q q 0 0 0 rg BT 128.82 383.25 Td (paper ) Tj ET Q q 0 0 0 rg BT 153.54 383.25 Td (to ) Tj ET Q q 0 0 0 rg BT 163.84 383.25 Td (fund ) Tj ET Q q 0 0 0 rg BT 184.69 383.25 Td (near) Tj ET Q q 0 0 0 rg BT 201.69 383.25 Td (-term ) Tj ET Q q 0 0 0 rg BT 225.86 383.25 Td (domestic ) Tj ET Q q 0 0 0 rg BT 264.48 383.25 Td (liquidity ) Tj ET Q q 0 0 0 rg BT 300.89 383.25 Td (requirements ) Tj ET Q q 0 0 0 rg BT 355.61 383.25 Td (during ) Tj ET Q q 0 0 0 rg BT 384.23 383.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 409.07 383.25 Td (The ) Tj ET Q q 0 0 0 rg BT 427.13 383.25 Td (average ) Tj ET Q q 0 0 0 rg BT 460.73 383.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 493.24 383.25 Td (of ) Tj ET Q q 0 0 0 rg BT 504.09 383.25 Td (commercial ) Tj ET Q q 0 0 0 rg BT 553.80 383.25 Td (paper ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 371.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 84.78 371.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 102.45 371.25 Td ($389 ) Tj ET Q q 0 0 0 rg BT 124.56 371.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 153.46 371.25 Td ( ) Tj ET Q q 0 0 0 rg BT 155.57 371.25 Td (at ) Tj ET Q q 0 0 0 rg BT 164.90 371.25 Td (a ) Tj ET Q q 0 0 0 rg BT 171.46 371.25 Td (weighted-average ) Tj ET Q q 0 0 0 rg BT 244.64 371.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 261.74 371.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.19 371.25 Td (1.17%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.02 371.25 Td ( ) Tj ET Q q 0 0 0 rg BT 300.14 371.25 Td (during ) Tj ET Q q 0 0 0 rg BT 328.36 371.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 352.82 371.25 Td (The ) Tj ET Q q 0 0 0 rg BT 370.48 371.25 Td (maximum ) Tj ET Q q 0 0 0 rg BT 413.15 371.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 445.26 371.25 Td (of ) Tj ET Q q 0 0 0 rg BT 455.71 371.25 Td (commercial ) Tj ET Q q 0 0 0 rg BT 505.02 371.25 Td (paper ) Tj ET Q q 0 0 0 rg BT 529.34 371.25 Td (outstanding ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 359.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.05 359.25 Td ($1.3 ) Tj ET Q q 0 0 0 rg BT 74.05 359.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.17 359.25 Td ( ) Tj ET Q q 0 0 0 rg BT 102.67 359.25 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 122.94 359.25 Td ($299 ) Tj ET Q q 0 0 0 rg BT 145.44 359.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 174.33 359.25 Td ( ) Tj ET Q q 0 0 0 rg BT 176.83 359.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 226.00 359.25 Td (at ) Tj ET Q q 0 0 0 rg BT 235.72 359.25 Td (December ) Tj ET Q q 0 0 0 rg BT 279.30 359.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 294.30 359.25 Td (2017.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 335.25 Td (Dividend ) Tj ET Q q 0 0 0 rg BT 75.68 335.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 116.48 335.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 138.37 335.25 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 158.34 335.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 184.45 335.25 Td ( ) Tj ET Q q 0 0 0 rg BT 186.92 335.25 Td (in ) Tj ET Q q 0 0 0 rg BT 197.17 335.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 219.63 335.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 236.54 335.25 Td ($2.5 ) Tj ET Q q 0 0 0 rg BT 256.51 335.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.62 335.25 Td ( ) Tj ET Q q 0 0 0 rg BT 285.09 335.25 Td (in ) Tj ET Q q 0 0 0 rg BT 295.33 335.25 Td (both ) Tj ET Q q 0 0 0 rg BT 315.58 335.25 Td (2016 ) Tj ET Q q 0 0 0 rg BT 338.05 335.25 Td (and ) Tj ET Q q 0 0 0 rg BT 354.95 335.25 Td (2015. ) Tj ET Q q 0 0 0 rg BT 379.92 335.25 Td (Dividend ) Tj ET Q q 0 0 0 rg BT 419.60 335.25 Td (decisions ) Tj ET Q q 0 0 0 rg BT 459.29 335.25 Td (are ) Tj ET Q q 0 0 0 rg BT 473.96 335.25 Td (made ) Tj ET Q q 0 0 0 rg BT 498.08 335.25 Td (on ) Tj ET Q q 0 0 0 rg BT 510.55 335.25 Td (a ) Tj ET Q q 0 0 0 rg BT 517.46 335.25 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 556.02 335.25 Td (basis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 323.25 Td (by ) Tj ET Q q 0 0 0 rg BT 48.59 323.25 Td (our ) Tj ET Q q 0 0 0 rg BT 64.51 323.25 Td (Board ) Tj ET Q q 0 0 0 rg BT 91.54 323.25 Td (of ) Tj ET Q q 0 0 0 rg BT 102.46 323.25 Td (Directors. ) Tj ET Q q 0 0 0 rg BT 144.18 323.25 Td (Annual ) Tj ET Q q 0 0 0 rg BT 176.21 323.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 205.45 323.25 Td (expenditures ) Tj ET Q q 0 0 0 rg BT 259.13 323.25 Td (were ) Tj ET Q q 0 0 0 rg BT 281.15 323.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 341.50 323.25 Td ($1.1 ) Tj ET Q q 0 0 0 rg BT 361.59 323.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.70 323.25 Td ( ) Tj ET Q q 0 0 0 rg BT 390.29 323.25 Td (in ) Tj ET Q q 0 0 0 rg BT 400.66 323.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 425.75 323.25 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.75 323.25 Td (1.2 ) Tj ET Q q 0 0 0 rg BT 445.84 323.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.95 323.25 Td ( ) Tj ET Q q 0 0 0 rg BT 474.54 323.25 Td (in ) Tj ET Q q 0 0 0 rg BT 484.91 323.25 Td (2016 ) Tj ET Q q 0 0 0 rg BT 507.50 323.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.52 323.25 Td ($800 ) Tj ET Q q 0 0 0 rg BT 547.11 323.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 311.25 Td (in ) Tj ET Q q 0 0 0 rg BT 47.24 311.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 70.70 311.25 Td (and ) Tj ET Q q 0 0 0 rg BT 88.60 311.25 Td (are ) Tj ET Q q 0 0 0 rg BT 104.27 311.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 143.27 311.25 Td (to ) Tj ET Q q 0 0 0 rg BT 154.51 311.25 Td (be ) Tj ET Q q 0 0 0 rg BT 167.41 311.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 228.63 311.25 Td ($1.0 ) Tj ET Q q 0 0 0 rg BT 249.59 311.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 275.70 311.25 Td ( ) Tj ET Q q 0 0 0 rg BT 279.16 311.25 Td (in ) Tj ET Q q 0 0 0 rg BT 290.40 311.25 Td (2018 ) Tj ET Q q 0 0 0 rg BT 313.87 311.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.77 311.25 Td ($850 ) Tj ET Q q 0 0 0 rg BT 355.23 311.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.12 311.25 Td ( ) Tj ET Q q 0 0 0 rg BT 387.58 311.25 Td (in ) Tj ET Q q 0 0 0 rg BT 398.82 311.25 Td (2019. ) Tj ET Q q 0 0 0 rg BT 424.53 311.25 Td (W) Tj ET Q q 0 0 0 rg BT 433.17 311.25 Td (e ) Tj ET Q q 0 0 0 rg BT 441.07 311.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 478.97 311.25 Td (to ) Tj ET Q q 0 0 0 rg BT 490.21 311.25 Td (expand ) Tj ET Q q 0 0 0 rg BT 522.55 311.25 Td (our ) Tj ET Q q 0 0 0 rg BT 539.34 311.25 Td (biologics ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 299.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 95.71 299.25 Td (capabilities ) Tj ET Q q 0 0 0 rg BT 142.64 299.25 Td (and ) Tj ET Q q 0 0 0 rg BT 158.48 299.25 Td (other ) Tj ET Q q 0 0 0 rg BT 180.42 299.25 Td (facility-related ) Tj ET Q q 0 0 0 rg BT 240.68 299.25 Td (activities. ) Tj ET Q q 0 0 0 rg BT 280.67 299.25 Td (For ) Tj ET Q q 0 0 0 rg BT 295.96 299.25 Td (example, ) Tj ET Q q 0 0 0 rg BT 333.73 299.25 Td (we ) Tj ET Q q 0 0 0 rg BT 346.79 299.25 Td (are ) Tj ET Q q 0 0 0 rg BT 360.39 299.25 Td (constructing ) Tj ET Q q 0 0 0 rg BT 411.23 299.25 Td (a ) Tj ET Q q 0 0 0 rg BT 417.06 299.25 Td (new ) Tj ET Q q 0 0 0 rg BT 435.12 299.25 Td (lar) Tj ET Q q 0 0 0 rg BT 445.49 299.25 Td (ge-scale ) Tj ET Q q 0 0 0 rg BT 479.64 299.25 Td (biologics ) Tj ET Q q 0 0 0 rg BT 517.70 299.25 Td (manufacturing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 287.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 66.82 287.25 Td (in ) Tj ET Q q 0 0 0 rg BT 77.10 287.25 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 107.91 287.25 Td (that ) Tj ET Q q 0 0 0 rg BT 125.41 287.25 Td (will ) Tj ET Q q 0 0 0 rg BT 143.47 287.25 Td (produce ) Tj ET Q q 0 0 0 rg BT 178.17 287.25 Td (multiple ) Tj ET Q q 0 0 0 rg BT 214.00 287.25 Td (therapies ) Tj ET Q q 0 0 0 rg BT 252.60 287.25 Td (for ) Tj ET Q q 0 0 0 rg BT 266.76 287.25 Td (our ) Tj ET Q q 0 0 0 rg BT 282.59 287.25 Td (growing ) Tj ET Q q 0 0 0 rg BT 318.42 287.25 Td (biologics ) Tj ET Q q 0 0 0 rg BT 357.58 287.25 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 395.08 287.25 Td (when ) Tj ET Q q 0 0 0 rg BT 419.24 287.25 Td (completed ) Tj ET Q q 0 0 0 rg BT 463.39 287.25 Td (in ) Tj ET Q q 0 0 0 rg BT 473.67 287.25 Td (2019. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 263.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.80 263.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 99.93 263.25 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 137.17 263.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 172.74 263.25 Td (non-current ) Tj ET Q q 0 0 0 rg BT 221.63 263.25 Td (marketable ) Tj ET Q q 0 0 0 rg BT 268.29 263.25 Td (securities, ) Tj ET Q q 0 0 0 rg BT 310.80 263.25 Td (which ) Tj ET Q q 0 0 0 rg BT 337.49 263.25 Td (are ) Tj ET Q q 0 0 0 rg BT 351.94 263.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 382.51 263.25 Td (to ) Tj ET Q q 0 0 0 rg BT 392.54 263.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 426.99 263.25 Td (in ) Tj ET Q q 0 0 0 rg BT 437.02 263.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 453.14 263.25 Td (value ) Tj ET Q q 0 0 0 rg BT 477.04 263.25 Td (as ) Tj ET Q q 0 0 0 rg BT 487.62 263.25 Td (a ) Tj ET Q q 0 0 0 rg BT 494.30 263.25 Td (result ) Tj ET Q q 0 0 0 rg BT 518.76 263.25 Td (of ) Tj ET Q q 0 0 0 rg BT 529.34 263.25 Td (interest ) Tj ET Q q 0 0 0 rg BT 561.02 263.25 Td (rate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 251.25 Td (fluctuations ) Tj ET Q q 0 0 0 rg BT 85.84 251.25 Td (and ) Tj ET Q q 0 0 0 rg BT 102.90 251.25 Td (other ) Tj ET Q q 0 0 0 rg BT 126.07 251.25 Td (market ) Tj ET Q q 0 0 0 rg BT 156.46 251.25 Td (factors. ) Tj ET Q q 0 0 0 rg BT 188.79 251.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 206.96 251.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 253.47 251.25 Td (policy ) Tj ET Q q 0 0 0 rg BT 281.08 251.25 Td (establishes ) Tj ET Q q 0 0 0 rg BT 327.03 251.25 Td (limits ) Tj ET Q q 0 0 0 rg BT 352.44 251.25 Td (on ) Tj ET Q q 0 0 0 rg BT 365.06 251.25 Td (the ) Tj ET Q q 0 0 0 rg BT 379.90 251.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 412.52 251.25 Td (and ) Tj ET Q q 0 0 0 rg BT 429.58 251.25 Td (time ) Tj ET Q q 0 0 0 rg BT 449.98 251.25 Td (to ) Tj ET Q q 0 0 0 rg BT 460.38 251.25 Td (maturity ) Tj ET Q q 0 0 0 rg BT 496.89 251.25 Td (of ) Tj ET Q q 0 0 0 rg BT 507.84 251.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 558.24 251.25 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 239.25 Td (any ) Tj ET Q q 0 0 0 rg BT 53.31 239.25 Td (institution. ) Tj ET Q q 0 0 0 rg BT 99.03 239.25 Td (The ) Tj ET Q q 0 0 0 rg BT 117.45 239.25 Td (policy ) Tj ET Q q 0 0 0 rg BT 145.31 239.25 Td (also ) Tj ET Q q 0 0 0 rg BT 164.29 239.25 Td (requires ) Tj ET Q q 0 0 0 rg BT 199.36 239.25 Td (that ) Tj ET Q q 0 0 0 rg BT 217.23 239.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 267.87 239.25 Td (are ) Tj ET Q q 0 0 0 rg BT 282.94 239.25 Td (only ) Tj ET Q q 0 0 0 rg BT 303.59 239.25 Td (entered ) Tj ET Q q 0 0 0 rg BT 335.88 239.25 Td (into ) Tj ET Q q 0 0 0 rg BT 354.31 239.25 Td (with ) Tj ET Q q 0 0 0 rg BT 374.96 239.25 Td (corporate ) Tj ET Q q 0 0 0 rg BT 415.58 239.25 Td (and ) Tj ET Q q 0 0 0 rg BT 432.88 239.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 470.73 239.25 Td (institutions ) Tj ET Q q 0 0 0 rg BT 518.06 239.25 Td (that ) Tj ET Q q 0 0 0 rg BT 535.92 239.25 Td (meet ) Tj ET Q q 0 0 0 rg BT 558.22 239.25 Td (high ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 227.25 Td (credit ) Tj ET Q q 0 0 0 rg BT 60.63 227.25 Td (quality ) Tj ET Q q 0 0 0 rg BT 90.27 227.25 Td (standards. ) Tj ET Q q 0 0 0 rg BT 132.40 227.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 156.47 227.25 Td (to ) Tj ET Q q 0 0 0 rg BT 166.11 227.25 Td (“Item ) Tj ET Q q 0 0 0 rg BT 190.74 227.25 Td (8. ) Tj ET Q q 0 0 0 rg BT 200.10 227.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 239.18 227.25 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.37 227.25 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 319.37 227.25 Td (. ) Tj ET Q q 0 0 0 rg BT 323.73 227.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 362.81 227.25 Td (Instruments ) Tj ET Q q 0 0 0 rg BT 411.89 227.25 Td (and ) Tj ET Q q 0 0 0 rg BT 428.19 227.25 Td (Fair ) Tj ET Q q 0 0 0 rg BT 446.03 227.25 Td (V) Tj ET Q q 0 0 0 rg BT 452.14 227.25 Td (alue ) Tj ET Q q 0 0 0 rg BT 470.66 227.25 Td (Measurements” ) Tj ET Q q 0 0 0 rg BT 535.28 227.25 Td (for ) Tj ET Q q 0 0 0 rg BT 548.80 227.25 Td (further ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 215.25 Td (information.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 191.25 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 191.25 Td (e ) Tj ET Q q 0 0 0 rg BT 52.04 191.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 91.09 191.25 Td (have ) Tj ET Q q 0 0 0 rg BT 112.92 191.25 Td (three ) Tj ET Q q 0 0 0 rg BT 135.87 191.25 Td (separate ) Tj ET Q q 0 0 0 rg BT 171.58 191.25 Td (revolving ) Tj ET Q q 0 0 0 rg BT 212.87 191.25 Td (credit ) Tj ET Q q 0 0 0 rg BT 238.59 191.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 275.98 191.25 Td (totaling ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.49 191.25 Td ($5.0 ) Tj ET Q q 0 0 0 rg BT 329.95 191.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.06 191.25 Td ( ) Tj ET Q q 0 0 0 rg BT 359.02 191.25 Td (from ) Tj ET Q q 0 0 0 rg BT 381.42 191.25 Td (a ) Tj ET Q q 0 0 0 rg BT 388.81 191.25 Td (syndicate ) Tj ET Q q 0 0 0 rg BT 429.54 191.25 Td (of ) Tj ET Q q 0 0 0 rg BT 440.82 191.25 Td (lenders. ) Tj ET Q q 0 0 0 rg BT 474.95 191.25 Td (The ) Tj ET Q q 0 0 0 rg BT 493.45 191.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 530.84 191.25 Td (provide ) Tj ET Q q 0 0 0 rg BT 564.35 191.25 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 179.25 Td (customary ) Tj ET Q q 0 0 0 rg BT 80.27 179.25 Td (terms ) Tj ET Q q 0 0 0 rg BT 105.09 179.25 Td (and ) Tj ET Q q 0 0 0 rg BT 122.14 179.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 166.42 179.25 Td (with ) Tj ET Q q 0 0 0 rg BT 186.81 179.25 Td (no ) Tj ET Q q 0 0 0 rg BT 199.42 179.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 237.01 179.25 Td (covenants. ) Tj ET Q q 0 0 0 rg BT 282.11 179.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 300.27 179.25 Td (364 ) Tj ET Q q 0 0 0 rg BT 317.88 179.25 Td (day ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 334.93 179.25 Td ($2.0 ) Tj ET Q q 0 0 0 rg BT 355.05 179.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.16 179.25 Td ( ) Tj ET Q q 0 0 0 rg BT 383.77 179.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 414.70 179.25 Td (expires ) Tj ET Q q 0 0 0 rg BT 446.19 179.25 Td (in ) Tj ET Q q 0 0 0 rg BT 456.58 179.25 Td (March ) Tj ET Q q 0 0 0 rg BT 485.29 179.25 Td (2018 ) Tj ET Q q 0 0 0 rg BT 507.90 179.25 Td (and ) Tj ET Q q 0 0 0 rg BT 524.95 179.25 Td (our ) Tj ET Q q 0 0 0 rg BT 540.89 179.25 Td (two ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.50 179.25 Td ($1.5 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 167.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 62.11 167.25 Td ( ) Tj ET Q q 0 0 0 rg BT 64.55 167.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 101.42 167.25 Td (were ) Tj ET Q q 0 0 0 rg BT 123.29 167.25 Td (extended ) Tj ET Q q 0 0 0 rg BT 161.82 167.25 Td (to ) Tj ET Q q 0 0 0 rg BT 172.04 167.25 Td (October ) Tj ET Q q 0 0 0 rg BT 206.68 167.25 Td (2021 ) Tj ET Q q 0 0 0 rg BT 229.12 167.25 Td (and ) Tj ET Q q 0 0 0 rg BT 246.00 167.25 Td (July ) Tj ET Q q 0 0 0 rg BT 265.11 167.25 Td (2022. ) Tj ET Q q 0 0 0 rg BT 290.05 167.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 308.04 167.25 Td (two ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.48 167.25 Td ($1.5 ) Tj ET Q q 0 0 0 rg BT 345.42 167.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.53 167.25 Td (, ) Tj ET Q q 0 0 0 rg BT 376.47 167.25 Td (five-year ) Tj ET Q q 0 0 0 rg BT 414.99 167.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 451.86 167.25 Td (are ) Tj ET Q q 0 0 0 rg BT 466.51 167.25 Td (extendable ) Tj ET Q q 0 0 0 rg BT 512.25 167.25 Td (annually ) Tj ET Q q 0 0 0 rg BT 549.13 167.25 Td (by ) Tj ET Q q 0 0 0 rg BT 561.57 167.25 Td (one ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 155.25 Td (year ) Tj ET Q q 0 0 0 rg BT 56.56 155.25 Td (on ) Tj ET Q q 0 0 0 rg BT 69.92 155.25 Td (the ) Tj ET Q q 0 0 0 rg BT 85.49 155.25 Td (anniversary ) Tj ET Q q 0 0 0 rg BT 135.49 155.25 Td (date ) Tj ET Q q 0 0 0 rg BT 155.50 155.25 Td (with ) Tj ET Q q 0 0 0 rg BT 176.64 155.25 Td (the ) Tj ET Q q 0 0 0 rg BT 192.21 155.25 Td (consent ) Tj ET Q q 0 0 0 rg BT 226.11 155.25 Td (of ) Tj ET Q q 0 0 0 rg BT 237.80 155.25 Td (the ) Tj ET Q q 0 0 0 rg BT 253.37 155.25 Td (lenders. ) Tj ET Q q 0 0 0 rg BT 288.11 155.25 Td (No ) Tj ET Q q 0 0 0 rg BT 303.68 155.25 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 352.59 155.25 Td (were ) Tj ET Q q 0 0 0 rg BT 375.38 155.25 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 425.40 155.25 Td (under ) Tj ET Q q 0 0 0 rg BT 451.52 155.25 Td (any ) Tj ET Q q 0 0 0 rg BT 469.32 155.25 Td (revolving ) Tj ET Q q 0 0 0 rg BT 511.00 155.25 Td (credit ) Tj ET Q q 0 0 0 rg BT 537.12 155.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 568.79 155.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 143.25 Td (December ) Tj ET Q q 0 0 0 rg BT 79.58 143.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 94.58 143.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 117.08 143.25 Td (or ) Tj ET Q q 0 0 0 rg BT 127.91 143.25 Td (2016.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 119.25 Td (Additional ) Tj ET Q q 0 0 0 rg BT 81.17 119.25 Td (regulations ) Tj ET Q q 0 0 0 rg BT 127.99 119.25 Td (in ) Tj ET Q q 0 0 0 rg BT 138.16 119.25 Td (the ) Tj ET Q q 0 0 0 rg BT 152.77 119.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 172.94 119.25 Td (could ) Tj ET Q q 0 0 0 rg BT 197.55 119.25 Td (be ) Tj ET Q q 0 0 0 rg BT 209.38 119.25 Td (passed ) Tj ET Q q 0 0 0 rg BT 238.43 119.25 Td (in ) Tj ET Q q 0 0 0 rg BT 248.60 119.25 Td (the ) Tj ET Q q 0 0 0 rg BT 263.21 119.25 Td (future ) Tj ET Q q 0 0 0 rg BT 289.48 119.25 Td (including ) Tj ET Q q 0 0 0 rg BT 329.65 119.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 372.03 119.25 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 415.50 119.25 Td (reform ) Tj ET Q q 0 0 0 rg BT 445.10 119.25 Td (initiatives, ) Tj ET Q q 0 0 0 rg BT 489.43 119.25 Td (further ) Tj ET Q q 0 0 0 rg BT 519.03 119.25 Td (changes ) Tj ET Q q 0 0 0 rg BT 553.62 119.25 Td (to ) Tj ET Q q 0 0 0 rg BT 563.79 119.25 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 107.25 Td (laws, ) Tj ET Q q 0 0 0 rg BT 60.13 107.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 103.42 107.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 135.04 107.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 156.67 107.25 Td (and ) Tj ET Q q 0 0 0 rg BT 174.41 107.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 212.69 107.25 Td (importation ) Tj ET Q q 0 0 0 rg BT 262.65 107.25 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 310.38 107.25 Td (which ) Tj ET Q q 0 0 0 rg BT 338.12 107.25 Td (may ) Tj ET Q q 0 0 0 rg BT 358.64 107.25 Td (reduce ) Tj ET Q q 0 0 0 rg BT 388.58 107.25 Td (our ) Tj ET Q q 0 0 0 rg BT 405.21 107.25 Td (results ) Tj ET Q q 0 0 0 rg BT 434.62 107.25 Td (of ) Tj ET Q q 0 0 0 rg BT 446.24 107.25 Td (operations, ) Tj ET Q q 0 0 0 rg BT 493.70 107.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 534.76 107.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 555.83 107.25 Td (flow) Tj ET Q q 0 0 0 rg BT 573.51 107.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 95.25 Td (liquidity ) Tj ET Q q 0 0 0 rg BT 72.25 95.25 Td (and ) Tj ET Q q 0 0 0 rg BT 89.05 95.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 126.39 95.25 Td (flexibility) Tj ET Q q 0 0 0 rg BT 165.18 95.25 Td (. ) Tj ET Q q 0 0 0 rg BT 169.87 95.25 Td (W) Tj ET Q q 0 0 0 rg BT 178.51 95.25 Td (e ) Tj ET Q q 0 0 0 rg BT 185.30 95.25 Td (continue ) Tj ET Q q 0 0 0 rg BT 222.10 95.25 Td (to ) Tj ET Q q 0 0 0 rg BT 232.24 95.25 Td (monitor ) Tj ET Q q 0 0 0 rg BT 266.26 95.25 Td (the ) Tj ET Q q 0 0 0 rg BT 280.84 95.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 318.19 95.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 347.76 95.25 Td (of ) Tj ET Q q 0 0 0 rg BT 358.45 95.25 Td (the ) Tj ET Q q 0 0 0 rg BT 373.03 95.25 Td (economic ) Tj ET Q q 0 0 0 rg BT 414.26 95.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 458.28 95.25 Td (in ) Tj ET Q q 0 0 0 rg BT 468.42 95.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 497.98 95.25 Td (European ) Tj ET Q q 0 0 0 rg BT 538.66 95.25 Td (and ) Tj ET Q q 0 0 0 rg BT 555.46 95.25 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 83.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 74.04 83.25 Td (and ) Tj ET Q q 0 0 0 rg BT 89.87 83.25 Td (the ) Tj ET Q q 0 0 0 rg BT 103.47 83.25 Td (related ) Tj ET Q q 0 0 0 rg BT 132.06 83.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 160.66 83.25 Td (on ) Tj ET Q q 0 0 0 rg BT 172.04 83.25 Td (prescription ) Tj ET Q q 0 0 0 rg BT 221.20 83.25 Td (trends, ) Tj ET Q q 0 0 0 rg BT 249.52 83.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 279.23 83.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 318.40 83.25 Td (and ) Tj ET Q q 0 0 0 rg BT 334.22 83.25 Td (creditworthiness ) Tj ET Q q 0 0 0 rg BT 401.70 83.25 Td (of ) Tj ET Q q 0 0 0 rg BT 411.42 83.25 Td (our ) Tj ET Q q 0 0 0 rg BT 426.14 83.25 Td (customers. ) Tj ET Q q 0 0 0 rg BT 470.47 83.25 Td (W) Tj ET Q q 0 0 0 rg BT 479.11 83.25 Td (e ) Tj ET Q q 0 0 0 rg BT 484.93 83.25 Td (believe ) Tj ET Q q 0 0 0 rg BT 515.19 83.25 Td (these ) Tj ET Q q 0 0 0 rg BT 537.13 83.25 Td (economic ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 71.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 80.17 71.25 Td (will ) Tj ET Q q 0 0 0 rg BT 98.22 71.25 Td (not ) Tj ET Q q 0 0 0 rg BT 113.50 71.25 Td (have ) Tj ET Q q 0 0 0 rg BT 134.88 71.25 Td (a ) Tj ET Q q 0 0 0 rg BT 141.82 71.25 Td (material ) Tj ET Q q 0 0 0 rg BT 177.07 71.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 206.79 71.25 Td (on ) Tj ET Q q 0 0 0 rg BT 219.29 71.25 Td (our ) Tj ET Q q 0 0 0 rg BT 235.12 71.25 Td (liquidity) Tj ET Q q 0 0 0 rg BT 268.36 71.25 Td (, ) Tj ET Q q 0 0 0 rg BT 273.36 71.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 293.63 71.25 Td (flow ) Tj ET Q q 0 0 0 rg BT 314.46 71.25 Td (or ) Tj ET Q q 0 0 0 rg BT 325.29 71.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 362.77 71.25 Td (flexibility) Tj ET Q q 0 0 0 rg BT 401.56 71.25 Td (.) Tj ET Q endstream endobj 89 0 obj <> endobj 90 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (44) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Cr) Tj ET Q q 0 0 0 rg BT 46.19 749.10 Td (edit Ratings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 65.78 725.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 108.18 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 125.58 725.10 Td (short-term ) Tj ET Q q 0 0 0 rg BT 170.21 725.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 195.93 725.10 Td (ratings ) Tj ET Q q 0 0 0 rg BT 226.12 725.10 Td (assigned ) Tj ET Q q 0 0 0 rg BT 263.52 725.10 Td (by ) Tj ET Q q 0 0 0 rg BT 276.49 725.10 Td (Moody's ) Tj ET Q q 0 0 0 rg BT 314.04 725.10 Td (Investors ) Tj ET Q q 0 0 0 rg BT 353.66 725.10 Td (Service ) Tj ET Q q 0 0 0 rg BT 386.61 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 401.13 725.10 Td (A2 ) Tj ET Q q 0 0 0 rg BT 416.32 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 433.72 725.10 Td (Prime-1, ) Tj ET Q q 0 0 0 rg BT 471.40 725.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 519.06 725.10 Td (, ) Tj ET Q q 0 0 0 rg BT 524.53 725.10 Td (with ) Tj ET Q q 0 0 0 rg BT 545.27 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 552.68 725.10 Td (stable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (rating ) Tj ET Q q 0 0 0 rg BT 61.37 713.10 Td (outlook. ) Tj ET Q q 0 0 0 rg BT 96.48 713.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 125.34 713.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 166.82 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 183.31 713.10 Td (short-term ) Tj ET Q q 0 0 0 rg BT 227.01 713.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 251.82 713.10 Td (ratings ) Tj ET Q q 0 0 0 rg BT 281.08 713.10 Td (assigned ) Tj ET Q q 0 0 0 rg BT 317.57 713.10 Td (by ) Tj ET Q q 0 0 0 rg BT 329.62 713.10 Td (Standard ) Tj ET Q q 0 0 0 rg BT 367.21 713.10 Td (& ) Tj ET Q q 0 0 0 rg BT 377.04 713.10 Td (Poor's ) Tj ET Q q 0 0 0 rg BT 403.67 713.10 Td (are ) Tj ET Q q 0 0 0 rg BT 417.47 713.10 Td (A+ ) Tj ET Q q 0 0 0 rg BT 432.38 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 448.42 713.10 Td (A-1+, ) Tj ET Q q 0 0 0 rg BT 474.15 713.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 521.81 713.10 Td (, ) Tj ET Q q 0 0 0 rg BT 526.36 713.10 Td (with ) Tj ET Q q 0 0 0 rg BT 546.19 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 552.67 713.10 Td (stable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (rating ) Tj ET Q q 0 0 0 rg BT 61.55 701.10 Td (outlook. ) Tj ET Q q 0 0 0 rg BT 96.83 701.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 125.87 701.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 167.52 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 184.19 701.10 Td (short-term ) Tj ET Q q 0 0 0 rg BT 228.06 701.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 253.05 701.10 Td (ratings ) Tj ET Q q 0 0 0 rg BT 282.49 701.10 Td (assigned ) Tj ET Q q 0 0 0 rg BT 319.15 701.10 Td (by ) Tj ET Q q 0 0 0 rg BT 331.38 701.10 Td (Fitch ) Tj ET Q q 0 0 0 rg BT 354.16 701.10 Td (are ) Tj ET Q q 0 0 0 rg BT 368.10 701.10 Td (A- ) Tj ET Q q 0 0 0 rg BT 380.87 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 397.53 701.10 Td (F2, ) Tj ET Q q 0 0 0 rg BT 412.82 701.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 460.48 701.10 Td (, ) Tj ET Q q 0 0 0 rg BT 465.20 701.10 Td (with ) Tj ET Q q 0 0 0 rg BT 485.20 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 491.86 701.10 Td (stable ) Tj ET Q q 0 0 0 rg BT 517.41 701.10 Td (rating ) Tj ET Q q 0 0 0 rg BT 542.96 701.10 Td (outlook. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.53 689.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 96.94 689.10 Td (ratings ) Tj ET Q q 0 0 0 rg BT 127.13 689.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 155.63 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 170.83 689.10 Td (agencies' ) Tj ET Q q 0 0 0 rg BT 210.03 689.10 Td (opinion ) Tj ET Q q 0 0 0 rg BT 243.56 689.10 Td (that ) Tj ET Q q 0 0 0 rg BT 261.53 689.10 Td (we ) Tj ET Q q 0 0 0 rg BT 276.16 689.10 Td (have ) Tj ET Q q 0 0 0 rg BT 298.02 689.10 Td (a ) Tj ET Q q 0 0 0 rg BT 305.43 689.10 Td (low ) Tj ET Q q 0 0 0 rg BT 323.41 689.10 Td (default ) Tj ET Q q 0 0 0 rg BT 354.14 689.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 372.12 689.10 Td (but ) Tj ET Q q 0 0 0 rg BT 387.87 689.10 Td (are ) Tj ET Q q 0 0 0 rg BT 403.05 689.10 Td (somewhat ) Tj ET Q q 0 0 0 rg BT 446.58 689.10 Td (susceptible ) Tj ET Q q 0 0 0 rg BT 493.99 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 504.74 689.10 Td (adverse ) Tj ET Q q 0 0 0 rg BT 538.25 689.10 Td (ef) Tj ET Q q 0 0 0 rg BT 545.84 689.10 Td (fects ) Tj ET Q q 0 0 0 rg BT 567.69 689.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 70.63 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 80.84 677.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 139.90 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 156.77 677.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 198.07 677.10 Td (conditions. ) Tj ET Q q 0 0 0 rg BT 244.66 677.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 262.63 677.10 Td (short-term ) Tj ET Q q 0 0 0 rg BT 306.71 677.10 Td (ratings ) Tj ET Q q 0 0 0 rg BT 336.36 677.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 364.32 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 378.96 677.10 Td (agencies' ) Tj ET Q q 0 0 0 rg BT 417.61 677.10 Td (opinion ) Tj ET Q q 0 0 0 rg BT 450.59 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 468.01 677.10 Td (we ) Tj ET Q q 0 0 0 rg BT 482.10 677.10 Td (have ) Tj ET Q q 0 0 0 rg BT 503.40 677.10 Td (good ) Tj ET Q q 0 0 0 rg BT 525.83 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 536.03 677.10 Td (extremely ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (strong ) Tj ET Q q 0 0 0 rg BT 63.31 665.10 Td (capacity ) Tj ET Q q 0 0 0 rg BT 98.92 665.10 Td (for ) Tj ET Q q 0 0 0 rg BT 112.89 665.10 Td (timely ) Tj ET Q q 0 0 0 rg BT 140.75 665.10 Td (repayment. ) Tj ET Q q 0 0 0 rg BT 187.25 665.10 Td (Any ) Tj ET Q q 0 0 0 rg BT 206.78 665.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 231.85 665.10 Td (rating ) Tj ET Q q 0 0 0 rg BT 257.48 665.10 Td (downgrade ) Tj ET Q q 0 0 0 rg BT 304.22 665.10 Td (may ) Tj ET Q q 0 0 0 rg BT 323.74 665.10 Td (af) Tj ET Q q 0 0 0 rg BT 331.33 665.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 348.62 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.15 665.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 394.89 665.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 412.18 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 422.82 665.10 Td (any ) Tj ET Q q 0 0 0 rg BT 439.56 665.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 459.09 665.10 Td (we ) Tj ET Q q 0 0 0 rg BT 473.05 665.10 Td (may ) Tj ET Q q 0 0 0 rg BT 492.58 665.10 Td (incur) Tj ET Q q 0 0 0 rg BT 512.72 665.10 Td (, ) Tj ET Q q 0 0 0 rg BT 517.53 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 532.06 665.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 548.24 665.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (value ) Tj ET Q q 0 0 0 rg BT 60.16 653.10 Td (of ) Tj ET Q q 0 0 0 rg BT 70.99 653.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 105.15 653.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 124.87 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 141.81 653.10 Td (our ) Tj ET Q q 0 0 0 rg BT 157.64 653.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 185.69 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 195.97 653.10 Td (access ) Tj ET Q q 0 0 0 rg BT 224.00 653.10 Td (the ) Tj ET Q q 0 0 0 rg BT 238.72 653.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 267.87 653.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 302.03 653.10 Td (generally) Tj ET Q q 0 0 0 rg BT 338.58 653.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (Cash Flows) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 612.10 Td (The following is a discussion of cash flow activities:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 589.60 320.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 589.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 589.60 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 589.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 589.60 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 589.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 589.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 561.60 320.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 561.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 561.60 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 561.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 561.60 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 561.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 561.60 70.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 589.6 m 429.5 589.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 589.6 m 502.5 589.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 589.6 m 576.5 589.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 593.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 386.50 593.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 459.50 593.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.00 593.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 580.17 Td (Cash flow provided by/\(used in\):) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 566.17 Td (Operating activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 566.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 566.17 Td (5,275) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 566.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.15 566.17 Td (3,058) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 566.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 566.17 Td (2,105) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 552.17 Td (Investing activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 552.22 Td (\(66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 552.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.15 552.17 Td (1,480) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 552.17 Td (\(1,572) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 552.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 538.17 Td (Financing activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 538.22 Td (\(4,077) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 538.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.80 538.22 Td (\(2,653) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 538.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 538.17 Td (\(3,624) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 538.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 508.7669921875 m 116.634765625 508.7669921875 l s q 0 0 0 rg BT 36.00 510.10 Td (Operating ) Tj ET Q q 0 0 0 rg BT 79.43 510.10 Td (Activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 492.10 Td (Cash ) Tj ET Q q 0 0 0 rg BT 59.11 492.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 80.55 492.10 Td (from ) Tj ET Q q 0 0 0 rg BT 103.09 492.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 143.96 492.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 183.17 492.10 Td (represents ) Tj ET Q q 0 0 0 rg BT 226.82 492.10 Td (the ) Tj ET Q q 0 0 0 rg BT 242.14 492.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 263.02 492.10 Td (receipts ) Tj ET Q q 0 0 0 rg BT 297.22 492.10 Td (and ) Tj ET Q q 0 0 0 rg BT 314.76 492.10 Td (disbursements ) Tj ET Q q 0 0 0 rg BT 375.09 492.10 Td (from ) Tj ET Q q 0 0 0 rg BT 397.64 492.10 Td (all ) Tj ET Q q 0 0 0 rg BT 410.74 492.10 Td (of ) Tj ET Q q 0 0 0 rg BT 422.18 492.10 Td (our ) Tj ET Q q 0 0 0 rg BT 438.61 492.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 477.82 492.10 Td (other ) Tj ET Q q 0 0 0 rg BT 501.48 492.10 Td (than ) Tj ET Q q 0 0 0 rg BT 521.80 492.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 561.57 492.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 480.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 75.91 480.10 Td (activities. ) Tj ET Q q 0 0 0 rg BT 116.66 480.10 Td (Operating ) Tj ET Q q 0 0 0 rg BT 158.79 480.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 178.71 480.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 199.19 480.10 Td (is ) Tj ET Q q 0 0 0 rg BT 208.01 480.10 Td (derived ) Tj ET Q q 0 0 0 rg BT 240.14 480.10 Td (by ) Tj ET Q q 0 0 0 rg BT 252.29 480.10 Td (adjusting ) Tj ET Q q 0 0 0 rg BT 291.10 480.10 Td (net ) Tj ET Q q 0 0 0 rg BT 305.47 480.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 341.49 480.10 Td (for ) Tj ET Q q 0 0 0 rg BT 355.30 480.10 Td (noncontrolling ) Tj ET Q q 0 0 0 rg BT 416.33 480.10 Td (interest, ) Tj ET Q q 0 0 0 rg BT 450.41 480.10 Td (non-cash ) Tj ET Q q 0 0 0 rg BT 488.66 480.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 528.57 480.10 Td (items, ) Tj ET Q q 0 0 0 rg BT 554.89 480.10 Td (gains ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 468.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.59 468.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 78.63 468.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 119.09 468.10 Td (to ) Tj ET Q q 0 0 0 rg BT 129.02 468.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 167.83 468.10 Td (and ) Tj ET Q q 0 0 0 rg BT 184.42 468.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 224.33 468.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 262.57 468.10 Td (and ) Tj ET Q q 0 0 0 rg BT 279.16 468.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 313.51 468.10 Td (in ) Tj ET Q q 0 0 0 rg BT 323.44 468.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 363.35 468.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 388.83 468.10 Td (and ) Tj ET Q q 0 0 0 rg BT 405.42 468.10 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 444.78 468.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 481.92 468.10 Td (from ) Tj ET Q q 0 0 0 rg BT 503.51 468.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 531.77 468.10 Td (dif) Tj ET Q q 0 0 0 rg BT 542.70 468.10 Td (ferences ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 456.10 Td (between ) Tj ET Q q 0 0 0 rg BT 71.72 456.10 Td (the ) Tj ET Q q 0 0 0 rg BT 86.34 456.10 Td (receipts ) Tj ET Q q 0 0 0 rg BT 119.84 456.10 Td (and ) Tj ET Q q 0 0 0 rg BT 136.69 456.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 177.42 456.10 Td (of ) Tj ET Q q 0 0 0 rg BT 188.16 456.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 208.33 456.10 Td (and ) Tj ET Q q 0 0 0 rg BT 225.18 456.10 Td (when ) Tj ET Q q 0 0 0 rg BT 249.24 456.10 Td (the ) Tj ET Q q 0 0 0 rg BT 263.87 456.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 314.04 456.10 Td (are ) Tj ET Q q 0 0 0 rg BT 328.65 456.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 374.92 456.10 Td (in ) Tj ET Q q 0 0 0 rg BT 385.10 456.10 Td (our ) Tj ET Q q 0 0 0 rg BT 400.84 456.10 Td (results ) Tj ET Q q 0 0 0 rg BT 429.35 456.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.09 456.10 Td (operations. ) Tj ET Q q 0 0 0 rg BT 486.12 456.10 Td (As ) Tj ET Q q 0 0 0 rg BT 499.64 456.10 Td (a ) Tj ET Q q 0 0 0 rg BT 506.48 456.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 533.61 456.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 568.22 456.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 444.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 55.96 444.10 Td (from ) Tj ET Q q 0 0 0 rg BT 77.58 444.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 117.53 444.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 155.82 444.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 183.53 444.10 Td (the ) Tj ET Q q 0 0 0 rg BT 197.94 444.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 226.24 444.10 Td (of ) Tj ET Q q 0 0 0 rg BT 236.75 444.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 256.71 444.10 Td (collections ) Tj ET Q q 0 0 0 rg BT 302.22 444.10 Td (from ) Tj ET Q q 0 0 0 rg BT 323.84 444.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 366.57 444.10 Td (and ) Tj ET Q q 0 0 0 rg BT 383.20 444.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 416.47 444.10 Td (partners; ) Tj ET Q q 0 0 0 rg BT 453.65 444.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 494.16 444.10 Td (to ) Tj ET Q q 0 0 0 rg BT 504.12 444.10 Td (suppliers, ) Tj ET Q q 0 0 0 rg BT 544.92 444.10 Td (alliance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 432.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 71.61 432.10 Td (and ) Tj ET Q q 0 0 0 rg BT 89.45 432.10 Td (employees; ) Tj ET Q q 0 0 0 rg BT 138.40 432.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 178.46 432.10 Td (discounts ) Tj ET Q q 0 0 0 rg BT 219.64 432.10 Td (and ) Tj ET Q q 0 0 0 rg BT 237.48 432.10 Td (rebates; ) Tj ET Q q 0 0 0 rg BT 271.98 432.10 Td (and ) Tj ET Q q 0 0 0 rg BT 289.82 432.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 305.44 432.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 347.17 432.10 Td (in ) Tj ET Q q 0 0 0 rg BT 358.35 432.10 Td (the ) Tj ET Q q 0 0 0 rg BT 373.97 432.10 Td (ordinary ) Tj ET Q q 0 0 0 rg BT 411.25 432.10 Td (course ) Tj ET Q q 0 0 0 rg BT 440.75 432.10 Td (of ) Tj ET Q q 0 0 0 rg BT 452.48 432.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 492.28 432.10 Td (For ) Tj ET Q q 0 0 0 rg BT 509.57 432.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 549.35 432.10 Td (annual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 420.10 Td (employee ) Tj ET Q q 0 0 0 rg BT 78.21 420.10 Td (bonuses ) Tj ET Q q 0 0 0 rg BT 113.78 420.10 Td (are ) Tj ET Q q 0 0 0 rg BT 129.33 420.10 Td (typically ) Tj ET Q q 0 0 0 rg BT 167.66 420.10 Td (paid ) Tj ET Q q 0 0 0 rg BT 188.22 420.10 Td (in ) Tj ET Q q 0 0 0 rg BT 199.34 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 214.90 420.10 Td (first ) Tj ET Q q 0 0 0 rg BT 234.35 420.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 266.01 420.10 Td (of ) Tj ET Q q 0 0 0 rg BT 277.68 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 293.24 420.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 341.02 420.10 Td (year) Tj ET Q q 0 0 0 rg BT 357.67 420.10 Td (. ) Tj ET Q q 0 0 0 rg BT 363.52 420.10 Td (In ) Tj ET Q q 0 0 0 rg BT 375.19 420.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 413.81 420.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 434.92 420.10 Td (collections ) Tj ET Q q 0 0 0 rg BT 481.58 420.10 Td (are ) Tj ET Q q 0 0 0 rg BT 497.13 420.10 Td (impacted ) Tj ET Q q 0 0 0 rg BT 537.12 420.10 Td (by ) Tj ET Q q 0 0 0 rg BT 550.46 420.10 Td (longer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 408.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 72.86 408.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 97.50 408.10 Td (for ) Tj ET Q q 0 0 0 rg BT 111.58 408.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 141.21 408.10 Td (biologic ) Tj ET Q q 0 0 0 rg BT 176.41 408.10 Td (products ) Tj ET Q q 0 0 0 rg BT 213.27 408.10 Td (in ) Tj ET Q q 0 0 0 rg BT 223.47 408.10 Td (the ) Tj ET Q q 0 0 0 rg BT 238.11 408.10 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 260.82 408.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 300.46 408.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 330.08 408.10 Td (products ) Tj ET Q q 0 0 0 rg BT 366.95 408.10 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 407.15 408.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.58 408.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 441.51 408.10 Td (Y) Tj ET Q q 0 0 0 rg BT 446.15 408.10 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 468.36 408.10 Td ( ) Tj ET Q q 0 0 0 rg BT 470.78 408.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 487.65 408.10 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.31 408.10 Td ( ) Tj ET Q q 0 0 0 rg BT 526.73 408.10 Td (\(120 ) Tj ET Q q 0 0 0 rg BT 547.48 408.10 Td (days ) Tj ET Q q 0 0 0 rg BT 568.24 408.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 396.10 Td (150 ) Tj ET Q q 0 0 0 rg BT 53.36 396.10 Td (days\). ) Tj ET Q q 0 0 0 rg BT 79.72 396.10 Td (The ) Tj ET Q q 0 0 0 rg BT 97.63 396.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 125.54 396.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 162.34 396.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 186.92 396.10 Td (are ) Tj ET Q q 0 0 0 rg BT 201.49 396.10 Td (used ) Tj ET Q q 0 0 0 rg BT 222.19 396.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.33 396.10 Td (more ) Tj ET Q q 0 0 0 rg BT 255.24 396.10 Td (closely ) Tj ET Q q 0 0 0 rg BT 285.93 396.10 Td (align ) Tj ET Q q 0 0 0 rg BT 308.29 396.10 Td (with ) Tj ET Q q 0 0 0 rg BT 328.44 396.10 Td (the ) Tj ET Q q 0 0 0 rg BT 343.02 396.10 Td (insurance ) Tj ET Q q 0 0 0 rg BT 383.70 396.10 Td (reimbursement ) Tj ET Q q 0 0 0 rg BT 446.04 396.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 474.52 396.10 Td (for ) Tj ET Q q 0 0 0 rg BT 488.55 396.10 Td (physicians ) Tj ET Q q 0 0 0 rg BT 533.13 396.10 Td (and ) Tj ET Q q 0 0 0 rg BT 549.93 396.10 Td (cancer ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 384.10 Td (centers ) Tj ET Q q 0 0 0 rg BT 66.82 384.10 Td (following ) Tj ET Q q 0 0 0 rg BT 108.20 384.10 Td (administration ) Tj ET Q q 0 0 0 rg BT 168.47 384.10 Td (to ) Tj ET Q q 0 0 0 rg BT 178.75 384.10 Td (the ) Tj ET Q q 0 0 0 rg BT 193.47 384.10 Td (patients.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 360.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.62 360.10 Td ($2.2 ) Tj ET Q q 0 0 0 rg BT 75.20 360.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 101.31 360.10 Td ( ) Tj ET Q q 0 0 0 rg BT 104.39 360.10 Td (change ) Tj ET Q q 0 0 0 rg BT 135.78 360.10 Td (in ) Tj ET Q q 0 0 0 rg BT 146.63 360.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 167.48 360.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 188.89 360.10 Td (from ) Tj ET Q q 0 0 0 rg BT 211.40 360.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 252.24 360.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 291.42 360.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 333.92 360.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.77 360.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.77 360.10 Td ( ) Tj ET Q q 0 0 0 rg BT 367.85 360.10 Td (was ) Tj ET Q q 0 0 0 rg BT 386.47 360.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 426.76 360.10 Td (attributable ) Tj ET Q q 0 0 0 rg BT 475.38 360.10 Td (to ) Tj ET Q q 0 0 0 rg BT 486.23 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 501.52 360.10 Td (following ) Tj ET Q q 0 0 0 rg BT 543.49 360.10 Td (items ) Tj ET Q q 0 0 0 rg BT 568.23 360.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 348.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 71.27 348.10 Td (to ) Tj ET Q q 0 0 0 rg BT 81.55 348.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 121.81 348.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 143.74 348.10 Td (and ) Tj ET Q q 0 0 0 rg BT 160.68 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 175.40 348.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 204.01 348.10 Td (of ) Tj ET Q q 0 0 0 rg BT 214.84 348.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 235.11 348.10 Td (collections ) Tj ET Q q 0 0 0 rg BT 280.93 348.10 Td (and ) Tj ET Q q 0 0 0 rg BT 297.87 348.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 338.70 348.10 Td (in ) Tj ET Q q 0 0 0 rg BT 348.97 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.69 348.10 Td (ordinary ) Tj ET Q q 0 0 0 rg BT 400.07 348.10 Td (course ) Tj ET Q q 0 0 0 rg BT 428.67 348.10 Td (of ) Tj ET Q q 0 0 0 rg BT 439.50 348.10 Td (business:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 336.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 336.10 Td (Lower ) Tj ET Q q 0 0 0 rg BT 100.60 336.10 Td (income ) Tj ET Q q 0 0 0 rg BT 132.53 336.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 147.25 336.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 188.07 336.10 Td (of ) Tj ET Q q 0 0 0 rg BT 198.90 336.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.16 336.10 Td ($1.5 ) Tj ET Q q 0 0 0 rg BT 279.16 336.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.28 336.10 Td (;) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 324.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 324.10 Td (Out-licensing ) Tj ET Q q 0 0 0 rg BT 128.93 324.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 166.97 324.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 177.80 324.10 Td ($470 ) Tj ET Q q 0 0 0 rg BT 200.30 324.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.19 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 231.69 324.10 Td (related ) Tj ET Q q 0 0 0 rg BT 261.39 324.10 Td (to ) Tj ET Q q 0 0 0 rg BT 271.67 324.10 Td (the ) Tj ET Q q 0 0 0 rg BT 286.39 324.10 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 317.78 324.10 Td (and ) Tj ET Q q 0 0 0 rg BT 334.71 324.10 Td (Roche ) Tj ET Q q 0 0 0 rg BT 362.76 324.10 Td (transactions; ) Tj ET Q q 0 0 0 rg BT 415.80 324.10 Td (and) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 312.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 312.10 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 113.94 312.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 157.54 312.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 195.57 312.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.40 312.10 Td ($481 ) Tj ET Q q 0 0 0 rg BT 228.90 312.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 257.80 312.10 Td ( ) Tj ET Q q 0 0 0 rg BT 260.30 312.10 Td (related ) Tj ET Q q 0 0 0 rg BT 290.00 312.10 Td (to ) Tj ET Q q 0 0 0 rg BT 300.28 312.10 Td (Merck's ) Tj ET Q q 0 0 0 rg BT 334.57 312.10 Td (PD-1 ) Tj ET Q q 0 0 0 rg BT 358.18 312.10 Td (antibody ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 395.68 312.10 Td (Keytruda*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.89 312.10 Td ( ) Tj ET Q q 0 0 0 rg BT 440.39 312.10 Td (\(BMS's ) Tj ET Q q 0 0 0 rg BT 473.04 312.10 Td (share\)) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 497.47 312.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 300.10 Td (Partially ) Tj ET Q q 0 0 0 rg BT 90.38 300.10 Td (of) Tj ET Q q 0 0 0 rg BT 98.53 300.10 Td (fset ) Tj ET Q q 0 0 0 rg BT 115.47 300.10 Td (by:) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 54.00 288.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 288.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 103.13 288.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 128.17 288.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 167.63 288.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 209.32 288.10 Td (of ) Tj ET Q q 0 0 0 rg BT 221.01 288.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.14 288.10 Td ($400 ) Tj ET Q q 0 0 0 rg BT 305.50 288.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 334.39 288.10 Td ( ) Tj ET Q q 0 0 0 rg BT 337.75 288.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 378.33 288.10 Td (due ) Tj ET Q q 0 0 0 rg BT 396.13 288.10 Td (to ) Tj ET Q q 0 0 0 rg BT 407.27 288.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.85 288.10 Td (CytomX, ) Tj ET Q q 0 0 0 rg BT 463.16 288.10 Td (Halozyme ) Tj ET Q q 0 0 0 rg BT 507.62 288.10 Td (and ) Tj ET Q q 0 0 0 rg BT 525.42 288.10 Td (Nitto ) Tj ET Q q 0 0 0 rg BT 549.34 288.10 Td (Denko ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 276.10 Td (transactions.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 264.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 264.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 102.27 264.10 Td (contributions ) Tj ET Q q 0 0 0 rg BT 157.54 264.10 Td (to ) Tj ET Q q 0 0 0 rg BT 167.82 264.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 201.43 264.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 225.04 264.10 Td (of ) Tj ET Q q 0 0 0 rg BT 235.87 264.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.13 264.10 Td ($300 ) Tj ET Q q 0 0 0 rg BT 318.63 264.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.52 264.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 246.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.62 246.10 Td ($1.0 ) Tj ET Q q 0 0 0 rg BT 75.20 246.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 101.31 246.10 Td ( ) Tj ET Q q 0 0 0 rg BT 104.39 246.10 Td (change ) Tj ET Q q 0 0 0 rg BT 135.78 246.10 Td (in ) Tj ET Q q 0 0 0 rg BT 146.63 246.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 167.48 246.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 188.89 246.10 Td (from ) Tj ET Q q 0 0 0 rg BT 211.40 246.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 252.24 246.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 291.42 246.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 333.92 246.10 Td (to ) Tj ET Q q 0 0 0 rg BT 344.77 246.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 367.85 246.10 Td (was ) Tj ET Q q 0 0 0 rg BT 386.47 246.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 426.76 246.10 Td (attributable ) Tj ET Q q 0 0 0 rg BT 475.38 246.10 Td (to ) Tj ET Q q 0 0 0 rg BT 486.23 246.10 Td (the ) Tj ET Q q 0 0 0 rg BT 501.52 246.10 Td (following ) Tj ET Q q 0 0 0 rg BT 543.49 246.10 Td (items ) Tj ET Q q 0 0 0 rg BT 568.23 246.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 234.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 71.27 234.10 Td (to ) Tj ET Q q 0 0 0 rg BT 81.55 234.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 121.81 234.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 143.74 234.10 Td (and ) Tj ET Q q 0 0 0 rg BT 160.68 234.10 Td (the ) Tj ET Q q 0 0 0 rg BT 175.40 234.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 204.01 234.10 Td (of ) Tj ET Q q 0 0 0 rg BT 214.84 234.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 235.11 234.10 Td (collections ) Tj ET Q q 0 0 0 rg BT 280.93 234.10 Td (and ) Tj ET Q q 0 0 0 rg BT 297.87 234.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 338.70 234.10 Td (in ) Tj ET Q q 0 0 0 rg BT 348.97 234.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.69 234.10 Td (ordinary ) Tj ET Q q 0 0 0 rg BT 400.07 234.10 Td (course ) Tj ET Q q 0 0 0 rg BT 428.67 234.10 Td (of ) Tj ET Q q 0 0 0 rg BT 439.50 234.10 Td (business:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 216.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 216.10 Td (The ) Tj ET Q q 0 0 0 rg BT 85.55 216.10 Td (wind-down ) Tj ET Q q 0 0 0 rg BT 133.60 216.10 Td (of ) Tj ET Q q 0 0 0 rg BT 144.43 216.10 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 159.15 216.10 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 190.81 216.10 Td ( ) Tj ET Q q 0 0 0 rg BT 193.31 216.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 226.89 216.10 Td (in ) Tj ET Q q 0 0 0 rg BT 237.17 216.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 259.67 216.10 Td (of ) Tj ET Q q 0 0 0 rg BT 270.50 216.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 330.76 216.10 Td ($700 ) Tj ET Q q 0 0 0 rg BT 353.26 216.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.15 216.10 Td (; ) Tj ET Q q 0 0 0 rg BT 387.43 216.10 Td (and) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 204.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 204.10 Td (Lower ) Tj ET Q q 0 0 0 rg BT 96.25 204.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 120.58 204.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 159.34 204.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 200.32 204.10 Td (of ) Tj ET Q q 0 0 0 rg BT 211.30 204.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 271.72 204.10 Td ($600 ) Tj ET Q q 0 0 0 rg BT 294.37 204.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.26 204.10 Td ( ) Tj ET Q q 0 0 0 rg BT 325.92 204.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 365.79 204.10 Td (due ) Tj ET Q q 0 0 0 rg BT 382.88 204.10 Td (to ) Tj ET Q q 0 0 0 rg BT 393.31 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 408.19 204.10 Td (Five-Prime ) Tj ET Q q 0 0 0 rg BT 455.84 204.10 Td (and ) Tj ET Q q 0 0 0 rg BT 472.93 204.10 Td (Promedior ) Tj ET Q q 0 0 0 rg BT 517.80 204.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 568.22 204.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 192.10 Td (2015.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 180.10 Td (Partially ) Tj ET Q q 0 0 0 rg BT 90.38 180.10 Td (of) Tj ET Q q 0 0 0 rg BT 98.53 180.10 Td (fset ) Tj ET Q q 0 0 0 rg BT 115.47 180.10 Td (by:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 168.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 168.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 97.77 168.10 Td (income ) Tj ET Q q 0 0 0 rg BT 129.70 168.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 144.42 168.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 185.24 168.10 Td (of ) Tj ET Q q 0 0 0 rg BT 196.07 168.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.33 168.10 Td ($1.4 ) Tj ET Q q 0 0 0 rg BT 276.33 168.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.45 168.10 Td (.) Tj ET Q endstream endobj 91 0 obj <> endobj 92 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (45) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 112.181640625 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Investing ) Tj ET Q q 0 0 0 rg BT 74.97 749.10 Td (Activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 731.10 Td (Cash ) Tj ET Q q 0 0 0 rg BT 58.59 731.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 113.39 731.10 Td (from ) Tj ET Q q 0 0 0 rg BT 135.42 731.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 174.67 731.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 213.36 731.10 Td (include ) Tj ET Q q 0 0 0 rg BT 245.39 731.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 265.75 731.10 Td (used ) Tj ET Q q 0 0 0 rg BT 286.67 731.10 Td (for ) Tj ET Q q 0 0 0 rg BT 300.92 731.10 Td (acquisitions, ) Tj ET Q q 0 0 0 rg BT 353.79 731.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 414.69 731.10 Td (and ) Tj ET Q q 0 0 0 rg BT 431.72 731.10 Td (facility-related ) Tj ET Q q 0 0 0 rg BT 493.17 731.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 522.41 731.10 Td (expenditures, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 719.10 Td (purchases ) Tj ET Q q 0 0 0 rg BT 76.81 719.10 Td (of ) Tj ET Q q 0 0 0 rg BT 86.53 719.10 Td (marketable ) Tj ET Q q 0 0 0 rg BT 132.33 719.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 171.47 719.10 Td (with ) Tj ET Q q 0 0 0 rg BT 190.64 719.10 Td (maturities ) Tj ET Q q 0 0 0 rg BT 232.01 719.10 Td (greater ) Tj ET Q q 0 0 0 rg BT 261.15 719.10 Td (than ) Tj ET Q q 0 0 0 rg BT 279.75 719.10 Td (90 ) Tj ET Q q 0 0 0 rg BT 291.13 719.10 Td (days ) Tj ET Q q 0 0 0 rg BT 310.84 719.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 343.87 719.10 Td (by ) Tj ET Q q 0 0 0 rg BT 355.26 719.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 392.18 719.10 Td (from ) Tj ET Q q 0 0 0 rg BT 413.00 719.10 Td (business ) Tj ET Q q 0 0 0 rg BT 448.27 719.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 495.76 719.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 538.25 719.10 Td (royalties\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 707.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 707.10 Td (the ) Tj ET Q q 0 0 0 rg BT 67.66 707.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 85.70 707.10 Td (and ) Tj ET Q q 0 0 0 rg BT 102.64 707.10 Td (maturity ) Tj ET Q q 0 0 0 rg BT 139.02 707.10 Td (of ) Tj ET Q q 0 0 0 rg BT 149.85 707.10 Td (marketable ) Tj ET Q q 0 0 0 rg BT 196.77 707.10 Td (securities.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 683.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.05 683.10 Td ($1.5 billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.16 683.10 Td ( change in cash flow from investing activities compared to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.76 683.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.76 683.10 Td ( was primarily attributable to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 671.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 671.10 Td (Lower ) Tj ET Q q 0 0 0 rg BT 100.67 671.10 Td (net ) Tj ET Q q 0 0 0 rg BT 115.45 671.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 137.46 671.10 Td (of ) Tj ET Q q 0 0 0 rg BT 148.35 671.10 Td (marketable ) Tj ET Q q 0 0 0 rg BT 195.34 671.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 235.67 671.10 Td (with ) Tj ET Q q 0 0 0 rg BT 256.02 671.10 Td (maturities ) Tj ET Q q 0 0 0 rg BT 298.57 671.10 Td (greater ) Tj ET Q q 0 0 0 rg BT 328.90 671.10 Td (than ) Tj ET Q q 0 0 0 rg BT 348.68 671.10 Td (90 ) Tj ET Q q 0 0 0 rg BT 361.25 671.10 Td (days ) Tj ET Q q 0 0 0 rg BT 382.14 671.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 393.04 671.10 Td ($745 ) Tj ET Q q 0 0 0 rg BT 415.61 671.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.50 671.10 Td ( ) Tj ET Q q 0 0 0 rg BT 447.07 671.10 Td (which ) Tj ET Q q 0 0 0 rg BT 474.07 671.10 Td (were ) Tj ET Q q 0 0 0 rg BT 496.07 671.10 Td (essentially ) Tj ET Q q 0 0 0 rg BT 540.85 671.10 Td (of) Tj ET Q q 0 0 0 rg BT 549.00 671.10 Td (fset ) Tj ET Q q 0 0 0 rg BT 566.00 671.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 659.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 106.71 659.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.99 659.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 137.25 659.10 Td (equivalents;) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 647.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 647.10 Td (Lower ) Tj ET Q q 0 0 0 rg BT 101.08 647.10 Td (business ) Tj ET Q q 0 0 0 rg BT 137.95 647.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 183.14 647.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 221.65 647.10 Td (of ) Tj ET Q q 0 0 0 rg BT 232.96 647.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 293.70 647.10 Td ($600 ) Tj ET Q q 0 0 0 rg BT 316.68 647.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 345.57 647.10 Td ( ) Tj ET Q q 0 0 0 rg BT 348.55 647.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 388.74 647.10 Td (due ) Tj ET Q q 0 0 0 rg BT 406.16 647.10 Td (to ) Tj ET Q q 0 0 0 rg BT 416.91 647.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 447.09 647.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 470.07 647.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 499.71 647.10 Td (and ) Tj ET Q q 0 0 0 rg BT 517.13 647.10 Td (investigational ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 635.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 89.59 635.10 Td ( ) Tj ET Q q 0 0 0 rg BT 92.09 635.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 135.13 635.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 179.86 635.10 Td (in ) Tj ET Q q 0 0 0 rg BT 190.13 635.10 Td (2016; ) Tj ET Q q 0 0 0 rg BT 215.41 635.10 Td (and) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 623.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 623.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 102.27 623.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 124.21 623.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 170.59 623.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 211.41 623.10 Td (of ) Tj ET Q q 0 0 0 rg BT 222.24 623.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 282.50 623.10 Td ($350 ) Tj ET Q q 0 0 0 rg BT 305.00 623.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.89 623.10 Td ( ) Tj ET Q q 0 0 0 rg BT 336.39 623.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 376.11 623.10 Td (due ) Tj ET Q q 0 0 0 rg BT 393.04 623.10 Td (to ) Tj ET Q q 0 0 0 rg BT 403.32 623.10 Td (the ) Tj ET Q q 0 0 0 rg BT 418.04 623.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 464.42 623.10 Td (of ) Tj ET Q q 0 0 0 rg BT 475.25 623.10 Td (IFM ) Tj ET Q q 0 0 0 rg BT 495.54 623.10 Td (in ) Tj ET Q q 0 0 0 rg BT 505.81 623.10 Td (2017.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 599.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.05 599.10 Td ($3.1 ) Tj ET Q q 0 0 0 rg BT 74.05 599.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.16 599.10 Td ( ) Tj ET Q q 0 0 0 rg BT 102.66 599.10 Td (change ) Tj ET Q q 0 0 0 rg BT 133.48 599.10 Td (in ) Tj ET Q q 0 0 0 rg BT 143.75 599.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 164.02 599.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 184.85 599.10 Td (from ) Tj ET Q q 0 0 0 rg BT 206.79 599.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 245.96 599.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 284.55 599.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 326.48 599.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.76 599.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.76 599.10 Td ( ) Tj ET Q q 0 0 0 rg BT 359.26 599.10 Td (was ) Tj ET Q q 0 0 0 rg BT 377.31 599.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 417.02 599.10 Td (attributable ) Tj ET Q q 0 0 0 rg BT 465.06 599.10 Td (to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 587.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 587.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 96.85 587.10 Td (net ) Tj ET Q q 0 0 0 rg BT 110.65 587.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 131.67 587.10 Td (of ) Tj ET Q q 0 0 0 rg BT 141.58 587.10 Td (marketable ) Tj ET Q q 0 0 0 rg BT 187.58 587.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 226.93 587.10 Td (of ) Tj ET Q q 0 0 0 rg BT 236.84 587.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.18 587.10 Td ($2.1 ) Tj ET Q q 0 0 0 rg BT 315.26 587.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 341.38 587.10 Td ( ) Tj ET Q q 0 0 0 rg BT 342.96 587.10 Td (in ) Tj ET Q q 0 0 0 rg BT 352.32 587.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 373.90 587.10 Td (which ) Tj ET Q q 0 0 0 rg BT 399.92 587.10 Td (were ) Tj ET Q q 0 0 0 rg BT 420.93 587.10 Td (reinvested ) Tj ET Q q 0 0 0 rg BT 463.61 587.10 Td (in ) Tj ET Q q 0 0 0 rg BT 472.97 587.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 492.32 587.10 Td (and ) Tj ET Q q 0 0 0 rg BT 508.34 587.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 527.69 587.10 Td (equivalents;) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 575.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 575.10 Td (Lower ) Tj ET Q q 0 0 0 rg BT 96.10 575.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 118.04 575.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 164.42 575.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 205.24 575.10 Td (of ) Tj ET Q q 0 0 0 rg BT 216.07 575.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 276.33 575.10 Td ($800 ) Tj ET Q q 0 0 0 rg BT 298.83 575.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.72 575.10 Td ( ) Tj ET Q q 0 0 0 rg BT 330.22 575.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 369.94 575.10 Td (due ) Tj ET Q q 0 0 0 rg BT 386.88 575.10 Td (to ) Tj ET Q q 0 0 0 rg BT 397.15 575.10 Td (the ) Tj ET Q q 0 0 0 rg BT 411.87 575.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 458.25 575.10 Td (of ) Tj ET Q q 0 0 0 rg BT 469.08 575.10 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 498.25 575.10 Td (in ) Tj ET Q q 0 0 0 rg BT 508.53 575.10 Td (2015; ) Tj ET Q q 0 0 0 rg BT 533.81 575.10 Td (and) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 563.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 563.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 99.18 563.10 Td (business ) Tj ET Q q 0 0 0 rg BT 136.98 563.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 183.10 563.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 222.55 563.10 Td (of ) Tj ET Q q 0 0 0 rg BT 234.79 563.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.46 563.10 Td ($600 ) Tj ET Q q 0 0 0 rg BT 320.37 563.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 349.26 563.10 Td ( ) Tj ET Q q 0 0 0 rg BT 353.17 563.10 Td (including ) Tj ET Q q 0 0 0 rg BT 394.85 563.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 433.20 563.10 Td (and ) Tj ET Q q 0 0 0 rg BT 451.55 563.10 Td (other ) Tj ET Q q 0 0 0 rg BT 476.00 563.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 522.13 563.10 Td (consideration ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 551.10 Td (received ) Tj ET Q q 0 0 0 rg BT 104.53 551.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 152.13 551.10 Td (to ) Tj ET Q q 0 0 0 rg BT 163.08 551.10 Td (the ) Tj ET Q q 0 0 0 rg BT 178.46 551.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 227.73 551.10 Td (of ) Tj ET Q q 0 0 0 rg BT 239.22 551.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 269.59 551.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 292.76 551.10 Td (brands ) Tj ET Q q 0 0 0 rg BT 322.58 551.10 Td (and ) Tj ET Q q 0 0 0 rg BT 340.19 551.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 402.23 551.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 419.82 551.10 Td ( ) Tj ET Q q 0 0 0 rg BT 422.99 551.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 466.69 551.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 512.08 551.10 Td (in ) Tj ET Q q 0 0 0 rg BT 523.02 551.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 546.19 551.10 Td (and ) Tj ET Q q 0 0 0 rg BT 563.79 551.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 539.10 Td (Mount ) Tj ET Q q 0 0 0 rg BT 96.49 539.10 Td (V) Tj ET Q q 0 0 0 rg BT 102.60 539.10 Td (ernon, ) Tj ET Q q 0 0 0 rg BT 130.37 539.10 Td (Indiana ) Tj ET Q q 0 0 0 rg BT 162.86 539.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 223.67 539.10 Td (facility) Tj ET Q q 0 0 0 rg BT 251.34 539.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 256.34 539.10 Td (Ixempra) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 289.66 539.10 Td (* ) Tj ET Q q 0 0 0 rg BT 297.16 539.10 Td (and ) Tj ET Q q 0 0 0 rg BT 314.10 539.10 Td (mature ) Tj ET Q q 0 0 0 rg BT 344.36 539.10 Td (and ) Tj ET Q q 0 0 0 rg BT 361.30 539.10 Td (other ) Tj ET Q q 0 0 0 rg BT 384.35 539.10 Td (OTC ) Tj ET Q q 0 0 0 rg BT 406.85 539.10 Td (product ) Tj ET Q q 0 0 0 rg BT 439.89 539.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 484.61 539.10 Td (in ) Tj ET Q q 0 0 0 rg BT 494.89 539.10 Td (2015.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 527.10 Td (Partially ) Tj ET Q q 0 0 0 rg BT 90.38 527.10 Td (of) Tj ET Q q 0 0 0 rg BT 98.53 527.10 Td (fset ) Tj ET Q q 0 0 0 rg BT 115.47 527.10 Td (by:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 515.10 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 515.10 Td (Higher ) Tj ET Q q 0 0 0 rg BT 97.77 515.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 126.92 515.10 Td (expenditures ) Tj ET Q q 0 0 0 rg BT 180.51 515.10 Td (of ) Tj ET Q q 0 0 0 rg BT 191.34 515.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.60 515.10 Td ($400 ) Tj ET Q q 0 0 0 rg BT 274.10 515.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.99 515.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 492.1669921875 m 116.6298828125 492.1669921875 l s q 0 0 0 rg BT 36.00 493.50 Td (Financing ) Tj ET Q q 0 0 0 rg BT 79.42 493.50 Td (Activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 475.50 Td (Cash ) Tj ET Q q 0 0 0 rg BT 58.12 475.50 Td (requirements ) Tj ET Q q 0 0 0 rg BT 112.45 475.50 Td (from ) Tj ET Q q 0 0 0 rg BT 134.01 475.50 Td (financing ) Tj ET Q q 0 0 0 rg BT 173.90 475.50 Td (activities ) Tj ET Q q 0 0 0 rg BT 212.12 475.50 Td (include ) Tj ET Q q 0 0 0 rg BT 243.68 475.50 Td (cash ) Tj ET Q q 0 0 0 rg BT 263.57 475.50 Td (used ) Tj ET Q q 0 0 0 rg BT 284.03 475.50 Td (to ) Tj ET Q q 0 0 0 rg BT 293.93 475.50 Td (pay ) Tj ET Q q 0 0 0 rg BT 310.49 475.50 Td (dividends, ) Tj ET Q q 0 0 0 rg BT 354.00 475.50 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 399.43 475.50 Td (common ) Tj ET Q q 0 0 0 rg BT 436.55 475.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 459.78 475.50 Td (and ) Tj ET Q q 0 0 0 rg BT 476.35 475.50 Td (repay ) Tj ET Q q 0 0 0 rg BT 500.68 475.50 Td (long-term ) Tj ET Q q 0 0 0 rg BT 542.24 475.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 561.58 475.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 463.50 Td (other ) Tj ET Q q 0 0 0 rg BT 59.05 463.50 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 107.10 463.50 Td (reduced ) Tj ET Q q 0 0 0 rg BT 141.24 463.50 Td (by ) Tj ET Q q 0 0 0 rg BT 153.74 463.50 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 191.78 463.50 Td (from ) Tj ET Q q 0 0 0 rg BT 213.72 463.50 Td (the ) Tj ET Q q 0 0 0 rg BT 228.44 463.50 Td (exercise ) Tj ET Q q 0 0 0 rg BT 263.69 463.50 Td (of ) Tj ET Q q 0 0 0 rg BT 274.52 463.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 298.13 463.50 Td (options ) Tj ET Q q 0 0 0 rg BT 330.08 463.50 Td (and ) Tj ET Q q 0 0 0 rg BT 347.02 463.50 Td (issuance ) Tj ET Q q 0 0 0 rg BT 383.39 463.50 Td (of ) Tj ET Q q 0 0 0 rg BT 394.22 463.50 Td (long-term ) Tj ET Q q 0 0 0 rg BT 436.16 463.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 455.87 463.50 Td (and ) Tj ET Q q 0 0 0 rg BT 472.81 463.50 Td (other ) Tj ET Q q 0 0 0 rg BT 495.86 463.50 Td (borrowings.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 439.50 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.05 439.50 Td ($1.4 ) Tj ET Q q 0 0 0 rg BT 74.05 439.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.16 439.50 Td ( ) Tj ET Q q 0 0 0 rg BT 102.66 439.50 Td (change ) Tj ET Q q 0 0 0 rg BT 133.48 439.50 Td (in ) Tj ET Q q 0 0 0 rg BT 143.75 439.50 Td (cash ) Tj ET Q q 0 0 0 rg BT 164.02 439.50 Td (flow ) Tj ET Q q 0 0 0 rg BT 184.85 439.50 Td (from ) Tj ET Q q 0 0 0 rg BT 206.79 439.50 Td (financing ) Tj ET Q q 0 0 0 rg BT 247.05 439.50 Td (activities ) Tj ET Q q 0 0 0 rg BT 285.65 439.50 Td (compared ) Tj ET Q q 0 0 0 rg BT 327.58 439.50 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.86 439.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.86 439.50 Td ( ) Tj ET Q q 0 0 0 rg BT 360.36 439.50 Td (was ) Tj ET Q q 0 0 0 rg BT 378.41 439.50 Td (primarily ) Tj ET Q q 0 0 0 rg BT 418.12 439.50 Td (attributable ) Tj ET Q q 0 0 0 rg BT 466.16 439.50 Td (to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 427.50 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 427.50 Td (Higher ) Tj ET Q q 0 0 0 rg BT 102.27 427.50 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 148.07 427.50 Td (of ) Tj ET Q q 0 0 0 rg BT 158.90 427.50 Td (common ) Tj ET Q q 0 0 0 rg BT 196.40 427.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 220.01 427.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 230.84 427.50 Td ($2.2 ) Tj ET Q q 0 0 0 rg BT 250.84 427.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 276.95 427.50 Td ( ) Tj ET Q q 0 0 0 rg BT 279.45 427.50 Td (primarily ) Tj ET Q q 0 0 0 rg BT 319.16 427.50 Td (due ) Tj ET Q q 0 0 0 rg BT 336.10 427.50 Td (to ) Tj ET Q q 0 0 0 rg BT 346.38 427.50 Td (the ) Tj ET Q q 0 0 0 rg BT 361.10 427.50 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 408.55 427.50 Td (share ) Tj ET Q q 0 0 0 rg BT 432.15 427.50 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 477.96 427.50 Td (agreements.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 415.50 Td (Partially ) Tj ET Q q 0 0 0 rg BT 90.38 415.50 Td (of) Tj ET Q q 0 0 0 rg BT 98.53 415.50 Td (fset ) Tj ET Q q 0 0 0 rg BT 115.47 415.50 Td (by:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 403.50 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 403.50 Td (Higher ) Tj ET Q q 0 0 0 rg BT 102.27 403.50 Td (net ) Tj ET Q q 0 0 0 rg BT 116.99 403.50 Td (borrowing ) Tj ET Q q 0 0 0 rg BT 161.15 403.50 Td (activity ) Tj ET Q q 0 0 0 rg BT 193.64 403.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 204.47 403.50 Td ($880 ) Tj ET Q q 0 0 0 rg BT 226.97 403.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 255.86 403.50 Td ( ) Tj ET Q q 0 0 0 rg BT 258.36 403.50 Td (primarily ) Tj ET Q q 0 0 0 rg BT 298.07 403.50 Td (to ) Tj ET Q q 0 0 0 rg BT 308.35 403.50 Td (fund ) Tj ET Q q 0 0 0 rg BT 329.18 403.50 Td (the ) Tj ET Q q 0 0 0 rg BT 343.89 403.50 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 389.70 403.50 Td (of ) Tj ET Q q 0 0 0 rg BT 400.53 403.50 Td (common ) Tj ET Q q 0 0 0 rg BT 438.03 403.50 Td (stock.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 379.50 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.05 379.50 Td ($1.0 billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.16 379.50 Td ( change in cash flow from financing activities compared to 2015 was primarily attributable to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 367.50 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 367.50 Td (Higher net borrowing activity of approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.72 367.50 Td ($1.3 billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.84 367.50 Td ( in 2016, primarily due to debt redemptions and reductions in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 355.50 Td (cash overdrafts in 2015.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 343.50 Td (Partially ) Tj ET Q q 0 0 0 rg BT 90.38 343.50 Td (of) Tj ET Q q 0 0 0 rg BT 98.53 343.50 Td (fset ) Tj ET Q q 0 0 0 rg BT 115.47 343.50 Td (by:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 331.50 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 67.50 331.50 Td (Repurchase ) Tj ET Q q 0 0 0 rg BT 116.65 331.50 Td (of ) Tj ET Q q 0 0 0 rg BT 127.48 331.50 Td (common ) Tj ET Q q 0 0 0 rg BT 164.97 331.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 188.58 331.50 Td (of ) Tj ET Q q 0 0 0 rg BT 199.41 331.50 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.67 331.50 Td ($200 ) Tj ET Q q 0 0 0 rg BT 282.17 331.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 311.06 331.50 Td ( ) Tj ET Q q 0 0 0 rg BT 313.56 331.50 Td (in ) Tj ET Q q 0 0 0 rg BT 323.84 331.50 Td (2016 ) Tj ET Q q 0 0 0 rg BT 346.34 331.50 Td (\(none ) Tj ET Q q 0 0 0 rg BT 371.61 331.50 Td (in ) Tj ET Q q 0 0 0 rg BT 381.88 331.50 Td (2015\).) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 307.50 Td (Contractual Obligations and Off-Balance Sheet ) Tj ET Q q 0 0 0 rg BT 240.17 307.50 Td (Arrangements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 290.50 Td (Payments due by period for our contractual obligations at December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.03 290.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.03 290.50 Td ( were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 256.00 163.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 199.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 203.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 253.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 257.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 307.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 256.00 49.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 468.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 256.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 256.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 228.00 163.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 199.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 203.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 253.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 257.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 307.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 228.00 49.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 468.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 228.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 228.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 200.00 163.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 199.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 203.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 253.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 257.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 307.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 200.00 49.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 468.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 200.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 200.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 172.00 163.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 199.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 203.50 172.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 253.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 257.50 172.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 307.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 311.50 172.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 172.00 49.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 172.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 468.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 172.00 50.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 172.00 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 172.00 50.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 203.5 268 m 253.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 253.5 268 m 257.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 257.5 268 m 307.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 307.5 268 m 311.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 311.5 268 m 361.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 268 m 365.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 268 m 414.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 268 m 418.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 418.5 268 m 468.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 468.5 268 m 472.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 472.5 268 m 522.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 522.5 268 m 526.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 268 m 576.5 268 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 203.5 256 m 253.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 257.5 256 m 307.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 311.5 256 m 361.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 256 m 414.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 418.5 256 m 468.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 472.5 256 m 522.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 256 m 576.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 257.5 256 m 307.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 311.5 256 m 361.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 256 m 414.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 418.5 256 m 468.5 256 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 203.5 158 m 253.5 158 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 257.5 158 m 307.5 158 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 311.5 158 m 361.5 158 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 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Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 34.35 122.90 Td (\(b\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 122.90 Td (Includes ) Tj ET Q q 0 0 0 rg BT 90.45 122.90 Td (only ) Tj ET Q q 0 0 0 rg BT 106.67 122.90 Td (short-term ) Tj ET Q q 0 0 0 rg BT 142.00 122.90 Td (uncertain ) Tj ET Q q 0 0 0 rg BT 173.76 122.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 185.53 122.90 Td (benefits ) Tj ET Q q 0 0 0 rg BT 212.86 122.90 Td (because ) Tj ET Q q 0 0 0 rg BT 240.17 122.90 Td (of ) Tj ET Q q 0 0 0 rg BT 248.84 122.90 Td (uncertainties ) Tj ET Q q 0 0 0 rg BT 291.71 122.90 Td (regarding ) Tj ET Q q 0 0 0 rg BT 324.36 122.90 Td (the ) Tj ET Q q 0 0 0 rg BT 336.13 122.90 Td (timing ) Tj ET Q q 0 0 0 rg BT 359.03 122.90 Td (of ) Tj ET Q q 0 0 0 rg BT 367.69 122.90 Td (resolution.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 34.35 113.30 Td (\(c\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 113.30 Td (Excludes ) Tj ET Q q 0 0 0 rg BT 92.67 113.30 Td (pension ) Tj ET Q q 0 0 0 rg BT 119.56 113.30 Td (and ) Tj ET Q q 0 0 0 rg BT 133.11 113.30 Td (other ) Tj ET Q q 0 0 0 rg BT 151.55 113.30 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 183.32 113.30 Td (because ) Tj ET Q q 0 0 0 rg BT 210.64 113.30 Td (of ) Tj ET Q q 0 0 0 rg BT 219.30 113.30 Td (uncertainties ) Tj ET Q q 0 0 0 rg BT 262.17 113.30 Td (regarding ) Tj ET Q q 0 0 0 rg BT 294.83 113.30 Td (the ) Tj ET Q q 0 0 0 rg BT 306.60 113.30 Td (timing ) Tj ET Q q 0 0 0 rg BT 329.49 113.30 Td (of ) Tj ET Q q 0 0 0 rg BT 338.15 113.30 Td (resolution.) Tj ET Q endstream endobj 93 0 obj <> endobj 94 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (46) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (In ) Tj ET Q q 0 0 0 rg BT 45.95 749.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 80.34 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 89.74 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 103.58 749.10 Td (above, ) Tj ET Q q 0 0 0 rg BT 131.58 749.10 Td (we ) Tj ET Q q 0 0 0 rg BT 144.86 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 158.68 749.10 Td (committed ) Tj ET Q q 0 0 0 rg BT 203.07 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 212.47 749.10 Td (an ) Tj ET Q q 0 0 0 rg BT 223.53 749.10 Td (aggregated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.01 749.10 Td ($17.0 ) Tj ET Q q 0 0 0 rg BT 293.13 749.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 319.25 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 320.87 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 330.82 749.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 367.43 749.10 Td (future ) Tj ET Q q 0 0 0 rg BT 392.92 749.10 Td (research ) Tj ET Q q 0 0 0 rg BT 427.85 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 443.91 749.10 Td (development ) Tj ET Q q 0 0 0 rg BT 497.18 749.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 537.68 749.10 Td (payments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 45.76 737.10 Td (third ) Tj ET Q q 0 0 0 rg BT 66.64 737.10 Td (parties ) Tj ET Q q 0 0 0 rg BT 95.28 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 108.93 737.10 Td (in-licensing, ) Tj ET Q q 0 0 0 rg BT 160.62 737.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 182.05 737.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 231.81 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 248.23 737.10 Td (development ) Tj ET Q q 0 0 0 rg BT 301.87 737.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 341.63 737.10 Td (including ) Tj ET Q q 0 0 0 rg BT 381.38 737.10 Td (early-stage ) Tj ET Q q 0 0 0 rg BT 427.23 737.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 471.99 737.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.31 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BT 455.79 725.10 Td (post ) Tj ET Q q 0 0 0 rg BT 474.26 725.10 Td (Phase ) Tj ET Q q 0 0 0 rg BT 499.39 725.10 Td (III ) Tj ET Q q 0 0 0 rg BT 511.18 725.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 542.41 725.10 Td (studies\). ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (Payments ) Tj ET Q q 0 0 0 rg BT 76.63 713.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 115.57 713.10 Td (are ) Tj ET Q q 0 0 0 rg BT 129.52 713.10 Td (due ) Tj ET Q q 0 0 0 rg BT 145.69 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 161.87 713.10 Td (payable ) Tj ET Q q 0 0 0 rg BT 194.71 713.10 Td (only ) Tj ET Q q 0 0 0 rg BT 214.22 713.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 235.96 713.10 Td (achievement ) Tj ET Q q 0 0 0 rg BT 288.23 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 298.30 713.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 327.24 713.10 Td (developmental ) Tj ET Q q 0 0 0 rg BT 387.85 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 404.03 713.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 446.86 713.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 491.37 713.10 Td (for ) Tj ET Q q 0 0 0 rg BT 504.77 713.10 Td (which ) Tj ET Q q 0 0 0 rg BT 530.95 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 544.91 713.10 Td (specific ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 64.34 701.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 93.23 701.10 Td (be ) Tj ET Q q 0 0 0 rg BT 104.90 701.10 Td (predicted. ) Tj ET Q q 0 0 0 rg BT 146.83 701.10 Td (Some ) Tj ET Q q 0 0 0 rg BT 171.84 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 182.40 701.10 Td (these ) Tj ET Q q 0 0 0 rg BT 205.18 701.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 252.94 701.10 Td (also ) Tj ET Q q 0 0 0 rg BT 271.28 701.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 304.06 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 317.95 701.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 365.71 701.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 410.72 701.10 Td (aggregating ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.15 701.10 Td ($3.5 ) Tj ET Q q 0 0 0 rg BT 479.88 701.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 506.00 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 508.23 701.10 Td (that ) Tj ET Q q 0 0 0 rg BT 525.45 701.10 Td (we ) Tj ET Q q 0 0 0 rg BT 539.34 701.10 Td (would ) Tj ET Q q 0 0 0 rg BT 566.57 701.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (obligated ) Tj ET Q q 0 0 0 rg BT 75.19 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 84.94 689.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 101.35 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 111.10 689.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 144.17 689.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 178.35 689.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 200.32 689.10 Td (achievement ) Tj ET Q q 0 0 0 rg BT 252.82 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 263.13 689.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 292.30 689.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 313.72 689.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 339.02 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 348.77 689.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 383.52 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 393.27 689.10 Td (royalties. ) Tj ET Q q 0 0 0 rg BT 432.03 689.10 Td (W) Tj ET Q q 0 0 0 rg BT 440.67 689.10 Td (e ) Tj ET Q q 0 0 0 rg BT 447.08 689.10 Td (also ) Tj ET Q q 0 0 0 rg BT 465.17 689.10 Td (have ) Tj ET Q q 0 0 0 rg BT 486.02 689.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 515.19 689.10 Td (manufacturing, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (development ) Tj ET Q q 0 0 0 rg BT 89.83 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 106.46 677.10 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 183.05 677.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 229.68 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 239.64 677.10 Td (connection ) Tj ET Q q 0 0 0 rg BT 285.70 677.10 Td (with ) Tj ET Q q 0 0 0 rg BT 305.66 677.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 338.93 677.10 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 397.48 677.10 Td (It ) Tj ET Q q 0 0 0 rg BT 405.77 677.10 Td (is ) Tj ET Q q 0 0 0 rg BT 414.62 677.10 Td (not ) Tj ET Q q 0 0 0 rg BT 429.59 677.10 Td (practicable ) Tj ET Q q 0 0 0 rg BT 475.63 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 485.59 677.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 521.10 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 535.50 677.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 567.68 677.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (these ) Tj ET Q q 0 0 0 rg BT 58.86 665.10 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 108.12 665.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 132.64 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 142.73 665.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 167.81 665.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 177.63 665.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 217.15 665.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.79 665.10 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 297.79 665.10 Td (. ) Tj ET Q q 0 0 0 rg BT 302.09 665.10 Td (Alliances” ) Tj ET Q q 0 0 0 rg BT 346.61 665.10 Td (for ) Tj ET Q q 0 0 0 rg BT 360.58 665.10 Td (further ) Tj ET Q q 0 0 0 rg BT 390.10 665.10 Td (information ) Tj ET Q q 0 0 0 rg BT 439.63 665.10 Td (regarding ) Tj ET Q q 0 0 0 rg BT 480.26 665.10 Td (our ) Tj ET Q q 0 0 0 rg BT 495.90 665.10 Td (alliances. ) Tj ET Q q 0 0 0 rg BT 535.53 665.10 Td (W) Tj ET Q q 0 0 0 rg BT 544.17 665.10 Td (e ) Tj ET Q q 0 0 0 rg BT 550.92 665.10 Td (do ) Tj ET Q q 0 0 0 rg BT 563.24 665.10 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (have ) Tj ET Q q 0 0 0 rg BT 57.65 653.10 Td (any ) Tj ET Q q 0 0 0 rg BT 74.86 653.10 Td (of) Tj ET Q q 0 0 0 rg BT 83.00 653.10 Td (f-balance ) Tj ET Q q 0 0 0 rg BT 122.97 653.10 Td (sheet ) Tj ET Q q 0 0 0 rg BT 146.28 653.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 202.92 653.10 Td (that ) Tj ET Q q 0 0 0 rg BT 220.68 653.10 Td (are ) Tj ET Q q 0 0 0 rg BT 235.66 653.10 Td (material ) Tj ET Q q 0 0 0 rg BT 271.19 653.10 Td (or ) Tj ET Q q 0 0 0 rg BT 282.29 653.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 328.37 653.10 Td (likely ) Tj ET Q q 0 0 0 rg BT 353.92 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 364.46 653.10 Td (become ) Tj ET Q q 0 0 0 rg BT 398.33 653.10 Td (material ) Tj ET Q q 0 0 0 rg BT 433.86 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 444.41 653.10 Td (our ) Tj ET Q q 0 0 0 rg BT 460.51 653.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 498.26 653.10 Td (condition ) Tj ET Q q 0 0 0 rg BT 538.80 653.10 Td (or ) Tj ET Q q 0 0 0 rg BT 549.90 653.10 Td (results ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.83 641.10 Td (operations.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (SEC Consent Order) Tj ET Q q 0 0 0 rg BT 121.93 617.10 Td ( / FCP) Tj ET Q q 0 0 0 rg BT 148.41 617.10 Td (A) Tj ET Q q 0 0 0 rg BT 155.08 617.10 Td ( Settlement) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (As ) Tj ET Q q 0 0 0 rg BT 50.17 593.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 95.44 593.10 Td (disclosed, ) Tj ET Q q 0 0 0 rg BT 138.21 593.10 Td (on ) Tj ET Q q 0 0 0 rg BT 150.59 593.10 Td (August 4, ) Tj ET Q q 0 0 0 rg BT 192.53 593.10 Td (2004, ) Tj ET Q q 0 0 0 rg BT 218.08 593.10 Td (we ) Tj ET Q q 0 0 0 rg BT 232.80 593.10 Td (entered ) Tj ET Q q 0 0 0 rg BT 265.27 593.10 Td (into ) Tj ET Q q 0 0 0 rg BT 283.88 593.10 Td (a ) Tj ET Q q 0 0 0 rg BT 291.38 593.10 Td (final ) Tj ET Q q 0 0 0 rg BT 312.75 593.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 356.91 593.10 Td (with ) Tj ET Q q 0 0 0 rg BT 377.74 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.01 593.10 Td (SEC, ) Tj ET Q q 0 0 0 rg BT 416.90 593.10 Td (concluding ) Tj ET Q q 0 0 0 rg BT 464.39 593.10 Td (an ) Tj ET Q q 0 0 0 rg BT 476.88 593.10 Td (investigation ) Tj ET Q q 0 0 0 rg BT 531.59 593.10 Td (concerning ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.00 581.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 112.12 581.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 153.24 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 170.48 581.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 217.15 581.10 Td (matters. ) Tj ET Q q 0 0 0 rg BT 251.68 581.10 Td (The ) Tj ET Q q 0 0 0 rg BT 270.03 581.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 313.92 581.10 Td (was ) Tj ET Q q 0 0 0 rg BT 332.28 581.10 Td (reached ) Tj ET Q q 0 0 0 rg BT 366.16 581.10 Td (through ) Tj ET Q q 0 0 0 rg BT 400.07 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 407.30 581.10 Td (Consent, ) Tj ET Q q 0 0 0 rg BT 445.38 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 452.62 581.10 Td (copy ) Tj ET Q q 0 0 0 rg BT 474.86 581.10 Td (of ) Tj ET Q q 0 0 0 rg BT 485.99 581.10 Td (which ) Tj ET Q q 0 0 0 rg BT 513.22 581.10 Td (was ) Tj ET Q q 0 0 0 rg BT 531.58 581.10 Td (attached ) Tj ET Q q 0 0 0 rg BT 567.69 581.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 67.94 569.10 Td (10 ) Tj ET Q q 0 0 0 rg BT 80.44 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 90.72 569.10 Td (our ) Tj ET Q q 0 0 0 rg BT 106.55 569.10 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 145.15 569.10 Td (report ) Tj ET Q q 0 0 0 rg BT 171.52 569.10 Td (on ) Tj ET Q q 0 0 0 rg BT 184.02 569.10 Td (Form ) Tj ET Q q 0 0 0 rg BT 208.19 569.10 Td (10-Q ) Tj ET Q q 0 0 0 rg BT 231.24 569.10 Td (for ) Tj ET Q q 0 0 0 rg BT 245.40 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 260.12 569.10 Td (period ) Tj ET Q q 0 0 0 rg BT 288.17 569.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 314.54 569.10 Td (September 30, ) Tj ET Q q 0 0 0 rg BT 374.81 569.10 Td (2004.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (Under ) Tj ET Q q 0 0 0 rg BT 62.97 545.10 Td (the ) Tj ET Q q 0 0 0 rg BT 77.16 545.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 101.35 545.10 Td (of ) Tj ET Q q 0 0 0 rg BT 111.65 545.10 Td (the ) Tj ET Q q 0 0 0 rg BT 125.85 545.10 Td (Consent, ) Tj ET Q q 0 0 0 rg BT 163.10 545.10 Td (we ) Tj ET Q q 0 0 0 rg BT 176.73 545.10 Td (agreed, ) Tj ET Q q 0 0 0 rg BT 207.86 545.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 238.16 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 247.91 545.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 277.09 545.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 309.05 545.10 Td (exceptions, ) Tj ET Q q 0 0 0 rg BT 356.29 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 366.04 545.10 Td (limit ) Tj ET Q q 0 0 0 rg BT 386.91 545.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 408.32 545.10 Td (of ) Tj ET Q q 0 0 0 rg BT 418.62 545.10 Td (all ) Tj ET Q q 0 0 0 rg BT 430.59 545.10 Td (products ) Tj ET Q q 0 0 0 rg BT 467.01 545.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 485.65 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 495.41 545.10 Td (our ) Tj ET Q q 0 0 0 rg BT 510.71 545.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 535.45 545.10 Td (customers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 79.85 533.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 132.31 533.10 Td (distributors, ) Tj ET Q q 0 0 0 rg BT 183.12 533.10 Td (hospitals, ) Tj ET Q q 0 0 0 rg BT 223.93 533.10 Td (retail ) Tj ET Q q 0 0 0 rg BT 247.22 533.10 Td (outlets, ) Tj ET Q q 0 0 0 rg BT 279.14 533.10 Td (pharmacies ) Tj ET Q q 0 0 0 rg BT 327.42 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 344.61 533.10 Td (government ) Tj ET Q q 0 0 0 rg BT 395.13 533.10 Td (purchasers\) ) Tj ET Q q 0 0 0 rg BT 443.97 533.10 Td (based ) Tj ET Q q 0 0 0 rg BT 469.49 533.10 Td (on ) Tj ET Q q 0 0 0 rg BT 482.24 533.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 520.52 533.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 554.93 533.10 Td (or ) Tj ET Q q 0 0 0 rg BT 566.01 533.10 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 72.23 521.10 Td (that ) Tj ET Q q 0 0 0 rg BT 89.58 521.10 Td (do ) Tj ET Q q 0 0 0 rg BT 101.92 521.10 Td (not ) Tj ET Q q 0 0 0 rg BT 117.05 521.10 Td (exceed ) Tj ET Q q 0 0 0 rg BT 147.15 521.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 207.26 521.10 Td (one ) Tj ET Q q 0 0 0 rg BT 224.04 521.10 Td (month ) Tj ET Q q 0 0 0 rg BT 251.95 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 262.63 521.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 303.30 521.10 Td (on ) Tj ET Q q 0 0 0 rg BT 315.65 521.10 Td (hand, ) Tj ET Q q 0 0 0 rg BT 339.93 521.10 Td (without ) Tj ET Q q 0 0 0 rg BT 372.84 521.10 Td (making ) Tj ET Q q 0 0 0 rg BT 405.18 521.10 Td (a ) Tj ET Q q 0 0 0 rg BT 411.97 521.10 Td (timely ) Tj ET Q q 0 0 0 rg BT 439.87 521.10 Td (public ) Tj ET Q q 0 0 0 rg BT 467.21 521.10 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 510.10 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 520.78 521.10 Td (any ) Tj ET Q q 0 0 0 rg BT 537.57 521.10 Td (change ) Tj ET Q q 0 0 0 rg BT 568.23 521.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (practice. ) Tj ET Q q 0 0 0 rg BT 72.72 509.10 Td (W) Tj ET Q q 0 0 0 rg BT 81.36 509.10 Td (e ) Tj ET Q q 0 0 0 rg BT 88.58 509.10 Td (also ) Tj ET Q q 0 0 0 rg BT 107.47 509.10 Td (agreed ) Tj ET Q q 0 0 0 rg BT 136.90 509.10 Td (in ) Tj ET Q q 0 0 0 rg BT 147.46 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 162.46 509.10 Td (Consent ) Tj ET Q q 0 0 0 rg BT 198.03 509.10 Td (to ) Tj ET Q q 0 0 0 rg BT 208.59 509.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 238.57 509.10 Td (measures ) Tj ET Q q 0 0 0 rg BT 278.56 509.10 Td (that ) Tj ET Q q 0 0 0 rg BT 296.34 509.10 Td (we ) Tj ET Q q 0 0 0 rg BT 310.78 509.10 Td (have ) Tj ET Q q 0 0 0 rg BT 332.44 509.10 Td (implemented ) Tj ET Q q 0 0 0 rg BT 387.43 509.10 Td (including: ) Tj ET Q q 0 0 0 rg BT 430.77 509.10 Td (\(a\) establishing ) Tj ET Q q 0 0 0 rg BT 494.92 509.10 Td (a ) Tj ET Q q 0 0 0 rg BT 502.15 509.10 Td (formal ) Tj ET Q q 0 0 0 rg BT 531.58 509.10 Td (review ) Tj ET Q q 0 0 0 rg BT 561.58 509.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (certification ) Tj ET Q q 0 0 0 rg BT 88.16 497.10 Td (process ) Tj ET Q q 0 0 0 rg BT 122.00 497.10 Td (of ) Tj ET Q q 0 0 0 rg BT 134.17 497.10 Td (our ) Tj ET Q q 0 0 0 rg BT 151.35 497.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 181.86 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 200.15 497.10 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 240.09 497.10 Td (reports ) Tj ET Q q 0 0 0 rg BT 271.71 497.10 Td (filed ) Tj ET Q q 0 0 0 rg BT 293.88 497.10 Td (with ) Tj ET Q q 0 0 0 rg BT 315.51 497.10 Td (the ) Tj ET Q q 0 0 0 rg BT 331.58 497.10 Td (SEC; ) Tj ET Q q 0 0 0 rg BT 356.55 497.10 Td (\(b\) establishing ) Tj ET Q q 0 0 0 rg BT 422.33 497.10 Td (a ) Tj ET Q q 0 0 0 rg BT 430.62 497.10 Td (business ) Tj ET Q q 0 0 0 rg BT 468.36 497.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 487.21 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 505.50 497.10 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 549.89 497.10 Td (group; ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (\(c\) retaining ) Tj ET Q q 0 0 0 rg BT 88.62 485.10 Td (an ) Tj ET Q q 0 0 0 rg BT 101.53 485.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 133.89 485.10 Td (consultant ) Tj ET Q q 0 0 0 rg BT 178.47 485.10 Td (to ) Tj ET Q q 0 0 0 rg BT 189.73 485.10 Td (comprehensively ) Tj ET Q q 0 0 0 rg BT 261.51 485.10 Td (study ) Tj ET Q q 0 0 0 rg BT 286.66 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 304.57 485.10 Td (help ) Tj ET Q q 0 0 0 rg BT 325.26 485.10 Td (re-engineer ) Tj ET Q q 0 0 0 rg BT 374.26 485.10 Td (our ) Tj ET Q q 0 0 0 rg BT 391.07 485.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 438.42 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 456.33 485.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 494.79 485.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 534.92 485.10 Td (processes; ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (\(d\) publicly ) Tj ET Q q 0 0 0 rg BT 85.45 473.10 Td (disclosing ) Tj ET Q q 0 0 0 rg BT 128.52 473.10 Td (any ) Tj ET Q q 0 0 0 rg BT 145.48 473.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 167.44 473.10 Td (incentives ) Tj ET Q q 0 0 0 rg BT 210.49 473.10 Td (of) Tj ET Q q 0 0 0 rg BT 218.64 473.10 Td (fered ) Tj ET Q q 0 0 0 rg BT 241.70 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 251.99 473.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 277.27 473.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 320.34 473.10 Td (for ) Tj ET Q q 0 0 0 rg BT 334.52 473.10 Td (the ) Tj ET Q q 0 0 0 rg BT 349.25 473.10 Td (purpose ) Tj ET Q q 0 0 0 rg BT 383.43 473.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.27 473.10 Td (inducing ) Tj ET Q q 0 0 0 rg BT 431.79 473.10 Td (them ) Tj ET Q q 0 0 0 rg BT 454.30 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 464.59 473.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 502.65 473.10 Td (products ) Tj ET Q q 0 0 0 rg BT 539.60 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 549.90 473.10 Td (excess ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.98 461.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 85.17 461.10 Td (demand; ) Tj ET Q q 0 0 0 rg BT 122.25 461.10 Td (and ) Tj ET Q q 0 0 0 rg BT 139.35 461.10 Td (\(e\) ensuring ) Tj ET Q q 0 0 0 rg BT 190.04 461.10 Td (that ) Tj ET Q q 0 0 0 rg BT 207.68 461.10 Td (our ) Tj ET Q q 0 0 0 rg BT 223.67 461.10 Td (budget ) Tj ET Q q 0 0 0 rg BT 253.54 461.10 Td (process ) Tj ET Q q 0 0 0 rg BT 286.18 461.10 Td (gives ) Tj ET Q q 0 0 0 rg BT 309.94 461.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 358.13 461.10 Td (weight ) Tj ET Q q 0 0 0 rg BT 388.00 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 398.43 461.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 425.53 461.10 Td (that ) Tj ET Q q 0 0 0 rg BT 443.18 461.10 Td (come ) Tj ET Q q 0 0 0 rg BT 467.48 461.10 Td (from ) Tj ET Q q 0 0 0 rg BT 489.57 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 504.44 461.10 Td (bottom ) Tj ET Q q 0 0 0 rg BT 535.43 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 545.86 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 560.73 461.10 Td (top, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 449.10 Td (not ) Tj ET Q q 0 0 0 rg BT 68.22 449.10 Td (just ) Tj ET Q q 0 0 0 rg BT 85.17 449.10 Td (from ) Tj ET Q q 0 0 0 rg BT 107.10 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 121.82 449.10 Td (top ) Tj ET Q q 0 0 0 rg BT 137.10 449.10 Td (to ) Tj ET Q q 0 0 0 rg BT 147.38 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 162.09 449.10 Td (bottom, ) Tj ET Q q 0 0 0 rg BT 195.43 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 212.37 449.10 Td (adequately ) Tj ET Q q 0 0 0 rg BT 258.18 449.10 Td (documenting ) Tj ET Q q 0 0 0 rg BT 312.89 449.10 Td (that ) Tj ET Q q 0 0 0 rg BT 330.38 449.10 Td (process.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 425.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.68 425.10 Td (have ) Tj ET Q q 0 0 0 rg BT 73.17 425.10 Td (established ) Tj ET Q q 0 0 0 rg BT 120.21 425.10 Td (a ) Tj ET Q q 0 0 0 rg BT 127.25 425.10 Td (company-wide ) Tj ET Q q 0 0 0 rg BT 189.28 425.10 Td (policy ) Tj ET Q q 0 0 0 rg BT 216.88 425.10 Td (to ) Tj ET Q q 0 0 0 rg BT 227.27 425.10 Td (limit ) Tj ET Q q 0 0 0 rg BT 248.77 425.10 Td (our ) Tj ET Q q 0 0 0 rg BT 264.70 425.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 286.75 425.10 Td (to ) Tj ET Q q 0 0 0 rg BT 297.13 425.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 322.50 425.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 365.66 425.10 Td (for ) Tj ET Q q 0 0 0 rg BT 379.92 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 394.75 425.10 Td (purpose ) Tj ET Q q 0 0 0 rg BT 429.01 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 439.95 425.10 Td (complying ) Tj ET Q q 0 0 0 rg BT 485.33 425.10 Td (with ) Tj ET Q q 0 0 0 rg BT 505.71 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 520.54 425.10 Td (Consent. ) Tj ET Q q 0 0 0 rg BT 558.23 425.10 Td (This ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (policy ) Tj ET Q q 0 0 0 rg BT 64.04 413.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 100.42 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 115.69 413.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 153.73 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 165.11 413.10 Td (various ) Tj ET Q q 0 0 0 rg BT 197.60 413.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 244.51 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 255.34 413.10 Td (monitor ) Tj ET Q q 0 0 0 rg BT 290.06 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 307.54 413.10 Td (limit ) Tj ET Q q 0 0 0 rg BT 329.48 413.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 351.97 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 362.80 413.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 388.61 413.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 432.21 413.10 Td (in ) Tj ET Q q 0 0 0 rg BT 443.04 413.10 Td (accordance ) Tj ET Q q 0 0 0 rg BT 491.05 413.10 Td (with ) Tj ET Q q 0 0 0 rg BT 511.87 413.10 Td (the ) Tj ET Q q 0 0 0 rg BT 527.14 413.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 552.41 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 413.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (Consent. ) Tj ET Q q 0 0 0 rg BT 73.80 401.10 Td (These ) Tj ET Q q 0 0 0 rg BT 100.39 401.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 146.98 401.10 Td (include ) Tj ET Q q 0 0 0 rg BT 179.13 401.10 Td (a ) Tj ET Q q 0 0 0 rg BT 186.28 401.10 Td (governance ) Tj ET Q q 0 0 0 rg BT 235.08 401.10 Td (process ) Tj ET Q q 0 0 0 rg BT 267.79 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 278.28 401.10 Td (escalate ) Tj ET Q q 0 0 0 rg BT 312.64 401.10 Td (to ) Tj ET Q q 0 0 0 rg BT 323.13 401.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 371.38 401.10 Td (management ) Tj ET Q q 0 0 0 rg BT 425.19 401.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 451.23 401.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 488.93 401.10 Td (questions ) Tj ET Q q 0 0 0 rg BT 529.43 401.10 Td (or ) Tj ET Q q 0 0 0 rg BT 540.48 401.10 Td (concerns ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (regarding ) Tj ET Q q 0 0 0 rg BT 77.39 389.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 126.56 389.10 Td (with ) Tj ET Q q 0 0 0 rg BT 147.42 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 162.71 389.10 Td (policy ) Tj ET Q q 0 0 0 rg BT 190.78 389.10 Td (and ) Tj ET Q q 0 0 0 rg BT 208.30 389.10 Td (timely ) Tj ET Q q 0 0 0 rg BT 236.93 389.10 Td (resolution ) Tj ET Q q 0 0 0 rg BT 280.00 389.10 Td (of ) Tj ET Q q 0 0 0 rg BT 291.41 389.10 Td (such ) Tj ET Q q 0 0 0 rg BT 312.82 389.10 Td (questions ) Tj ET Q q 0 0 0 rg BT 353.67 389.10 Td (or ) Tj ET Q q 0 0 0 rg BT 365.08 389.10 Td (concerns. ) Tj ET Q q 0 0 0 rg BT 406.19 389.10 Td (In ) Tj ET Q q 0 0 0 rg BT 417.60 389.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 455.95 389.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 505.12 389.10 Td (with ) Tj ET Q q 0 0 0 rg BT 525.98 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 541.27 389.10 Td (policy ) Tj ET Q q 0 0 0 rg BT 569.34 389.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (monitored ) Tj ET Q q 0 0 0 rg BT 79.60 377.10 Td (on ) Tj ET Q q 0 0 0 rg BT 92.10 377.10 Td (a ) Tj ET Q q 0 0 0 rg BT 99.04 377.10 Td (regular ) Tj ET Q q 0 0 0 rg BT 129.86 377.10 Td (basis.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 353.10 Td (e ) Tj ET Q q 0 0 0 rg BT 52.08 353.10 Td (maintain ) Tj ET Q q 0 0 0 rg BT 90.07 353.10 Td (DSAs ) Tj ET Q q 0 0 0 rg BT 116.97 353.10 Td (with ) Tj ET Q q 0 0 0 rg BT 137.75 353.10 Td (our ) Tj ET Q q 0 0 0 rg BT 154.09 353.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 174.87 353.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 238.95 353.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 291.66 353.10 Td (which ) Tj ET Q q 0 0 0 rg BT 319.10 353.10 Td (account ) Tj ET Q q 0 0 0 rg BT 353.20 353.10 Td (for ) Tj ET Q q 0 0 0 rg BT 367.86 353.10 Td (nearly ) Tj ET Q q 0 0 0 rg BT 395.85 353.10 Td (100% ) Tj ET Q q 0 0 0 rg BT 422.18 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 433.51 353.10 Td (our ) Tj ET Q q 0 0 0 rg BT 449.85 353.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 473.96 353.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 494.75 353.10 Td (revenues. ) Tj ET Q q 0 0 0 rg BT 535.79 353.10 Td (Under ) Tj ET Q q 0 0 0 rg BT 563.78 353.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (current ) Tj ET Q q 0 0 0 rg BT 66.73 341.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 91.37 341.10 Td (of ) Tj ET Q q 0 0 0 rg BT 102.12 341.10 Td (the ) Tj ET Q q 0 0 0 rg BT 116.76 341.10 Td (DSAs, ) Tj ET Q q 0 0 0 rg BT 145.57 341.10 Td (our ) Tj ET Q q 0 0 0 rg BT 161.32 341.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 207.06 341.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 250.02 341.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 282.99 341.10 Td (us ) Tj ET Q q 0 0 0 rg BT 294.30 341.10 Td (with ) Tj ET Q q 0 0 0 rg BT 314.50 341.10 Td (weekly ) Tj ET Q q 0 0 0 rg BT 345.79 341.10 Td (information ) Tj ET Q q 0 0 0 rg BT 395.43 341.10 Td (with ) Tj ET Q q 0 0 0 rg BT 415.62 341.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 446.36 341.10 Td (to ) Tj ET Q q 0 0 0 rg BT 456.56 341.10 Td (months ) Tj ET Q q 0 0 0 rg BT 488.42 341.10 Td (on ) Tj ET Q q 0 0 0 rg BT 500.84 341.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 522.70 341.10 Td (product-level ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (inventories ) Tj ET Q q 0 0 0 rg BT 82.73 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 99.47 329.10 Td (the ) Tj ET Q q 0 0 0 rg BT 113.98 329.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 146.27 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 156.90 329.10 Td (out-movement ) Tj ET Q q 0 0 0 rg BT 217.52 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 228.15 329.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 267.22 329.10 Td (The ) Tj ET Q q 0 0 0 rg BT 285.06 329.10 Td (three ) Tj ET Q q 0 0 0 rg BT 307.34 329.10 Td (lar) Tj ET Q q 0 0 0 rg BT 317.71 329.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 336.11 329.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 385.62 329.10 Td (currently ) Tj ET Q q 0 0 0 rg BT 424.01 329.10 Td (account ) Tj ET Q q 0 0 0 rg BT 457.40 329.10 Td (for ) Tj ET Q q 0 0 0 rg BT 471.36 329.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 531.42 329.10 Td (95% ) Tj ET Q q 0 0 0 rg BT 552.04 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 562.67 329.10 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 59.09 317.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 78.85 317.10 Td (revenues. ) Tj ET Q q 0 0 0 rg BT 118.72 317.10 Td (The ) Tj ET Q q 0 0 0 rg BT 136.24 317.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 176.55 317.10 Td (information ) Tj ET Q q 0 0 0 rg BT 225.73 317.10 Td (received ) Tj ET Q q 0 0 0 rg BT 261.57 317.10 Td (from ) Tj ET Q q 0 0 0 rg BT 282.99 317.10 Td (our ) Tj ET Q q 0 0 0 rg BT 298.29 317.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 349.98 317.10 Td (together ) Tj ET Q q 0 0 0 rg BT 384.72 317.10 Td (with ) Tj ET Q q 0 0 0 rg BT 404.47 317.10 Td (our ) Tj ET Q q 0 0 0 rg BT 419.78 317.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 452.30 317.10 Td (information, ) Tj ET Q q 0 0 0 rg BT 503.99 317.10 Td (is ) Tj ET Q q 0 0 0 rg BT 512.63 317.10 Td (used ) Tj ET Q q 0 0 0 rg BT 532.94 317.10 Td (to ) Tj ET Q q 0 0 0 rg BT 542.69 317.10 Td (estimate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (months ) Tj ET Q q 0 0 0 rg BT 66.87 305.10 Td (on ) Tj ET Q q 0 0 0 rg BT 78.30 305.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 99.16 305.10 Td (product ) Tj ET Q q 0 0 0 rg BT 131.14 305.10 Td (level ) Tj ET Q q 0 0 0 rg BT 152.00 305.10 Td (inventories ) Tj ET Q q 0 0 0 rg BT 197.86 305.10 Td (at ) Tj ET Q q 0 0 0 rg BT 206.50 305.10 Td (these ) Tj ET Q q 0 0 0 rg BT 228.47 305.10 Td (wholesalers. ) Tj ET Q q 0 0 0 rg BT 279.50 305.10 Td (W) Tj ET Q q 0 0 0 rg BT 288.14 305.10 Td (e ) Tj ET Q q 0 0 0 rg BT 294.00 305.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 328.75 305.10 Td (months ) Tj ET Q q 0 0 0 rg BT 359.62 305.10 Td (on ) Tj ET Q q 0 0 0 rg BT 371.05 305.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 391.91 305.10 Td (product ) Tj ET Q q 0 0 0 rg BT 423.89 305.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 463.64 305.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 488.39 305.10 Td (for ) Tj ET Q q 0 0 0 rg BT 501.47 305.10 Td (our ) Tj ET Q q 0 0 0 rg BT 516.23 305.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 535.44 305.10 Td (business’) Tj ET Q q 0 0 0 rg BT 572.11 305.10 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 81.86 293.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 124.95 293.10 Td (other ) Tj ET Q q 0 0 0 rg BT 148.04 293.10 Td (than ) Tj ET Q q 0 0 0 rg BT 167.80 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 182.56 293.10 Td (three ) Tj ET Q q 0 0 0 rg BT 205.09 293.10 Td (lar) Tj ET Q q 0 0 0 rg BT 215.46 293.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 234.11 293.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 283.86 293.10 Td (by ) Tj ET Q q 0 0 0 rg BT 296.41 293.10 Td (extrapolating ) Tj ET Q q 0 0 0 rg BT 351.71 293.10 Td (from ) Tj ET Q q 0 0 0 rg BT 373.69 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 388.45 293.10 Td (months ) Tj ET Q q 0 0 0 rg BT 420.44 293.10 Td (on ) Tj ET Q q 0 0 0 rg BT 432.99 293.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 454.97 293.10 Td (calculated ) Tj ET Q q 0 0 0 rg BT 498.04 293.10 Td (for ) Tj ET Q q 0 0 0 rg BT 512.25 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 527.01 293.10 Td (three ) Tj ET Q q 0 0 0 rg BT 549.54 293.10 Td (lar) Tj ET Q q 0 0 0 rg BT 559.90 293.10 Td (gest ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (wholesalers. ) Tj ET Q q 0 0 0 rg BT 88.16 281.10 Td (In ) Tj ET Q q 0 0 0 rg BT 98.95 281.10 Td (contrast, ) Tj ET Q q 0 0 0 rg BT 135.56 281.10 Td (our ) Tj ET Q q 0 0 0 rg BT 151.35 281.10 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 189.92 281.10 Td (business ) Tj ET Q q 0 0 0 rg BT 226.26 281.10 Td (has ) Tj ET Q q 0 0 0 rg BT 242.05 281.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 294.50 281.10 Td (more ) Tj ET Q q 0 0 0 rg BT 317.50 281.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 342.72 281.10 Td (customers, ) Tj ET Q q 0 0 0 rg BT 388.22 281.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 419.01 281.10 Td (information ) Tj ET Q q 0 0 0 rg BT 468.68 281.10 Td (on ) Tj ET Q q 0 0 0 rg BT 481.13 281.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 506.35 281.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 545.46 281.10 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (level ) Tj ET Q q 0 0 0 rg BT 58.58 269.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 100.05 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 117.64 269.10 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 177.99 269.10 Td (out-movement ) Tj ET Q q 0 0 0 rg BT 239.46 269.10 Td (information ) Tj ET Q q 0 0 0 rg BT 289.82 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 307.40 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 322.77 269.10 Td (reliability ) Tj ET Q q 0 0 0 rg BT 364.79 269.10 Td (of ) Tj ET Q q 0 0 0 rg BT 376.27 269.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 422.18 269.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 456.98 269.10 Td (information, ) Tj ET Q q 0 0 0 rg BT 509.84 269.10 Td (where ) Tj ET Q q 0 0 0 rg BT 537.42 269.10 Td (available, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (varies ) Tj ET Q q 0 0 0 rg BT 61.86 257.10 Td (widely) Tj ET Q q 0 0 0 rg BT 88.42 257.10 Td (. ) Tj ET Q q 0 0 0 rg BT 92.47 257.10 Td (Accordingly) Tj ET Q q 0 0 0 rg BT 141.80 257.10 Td (, ) Tj ET Q q 0 0 0 rg BT 146.28 257.10 Td (we ) Tj ET Q q 0 0 0 rg BT 159.92 257.10 Td (rely ) Tj ET Q q 0 0 0 rg BT 177.45 257.10 Td (on ) Tj ET Q q 0 0 0 rg BT 189.43 257.10 Td (a ) Tj ET Q q 0 0 0 rg BT 195.85 257.10 Td (variety ) Tj ET Q q 0 0 0 rg BT 225.59 257.10 Td (of ) Tj ET Q q 0 0 0 rg BT 235.90 257.10 Td (methods ) Tj ET Q q 0 0 0 rg BT 271.77 257.10 Td (to ) Tj ET Q q 0 0 0 rg BT 281.53 257.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 316.83 257.10 Td (months ) Tj ET Q q 0 0 0 rg BT 348.26 257.10 Td (on ) Tj ET Q q 0 0 0 rg BT 360.24 257.10 Td (hand ) Tj ET Q q 0 0 0 rg BT 381.65 257.10 Td (product ) Tj ET Q q 0 0 0 rg BT 414.18 257.10 Td (level ) Tj ET Q q 0 0 0 rg BT 435.59 257.10 Td (inventories ) Tj ET Q q 0 0 0 rg BT 482.01 257.10 Td (for ) Tj ET Q q 0 0 0 rg BT 495.65 257.10 Td (these ) Tj ET Q q 0 0 0 rg BT 518.18 257.10 Td (business ) Tj ET Q q 0 0 0 rg BT 554.05 257.10 Td (units.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 233.10 Td (e ) Tj ET Q q 0 0 0 rg BT 51.58 233.10 Td (believe ) Tj ET Q q 0 0 0 rg BT 82.95 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 97.67 233.10 Td (above-described ) Tj ET Q q 0 0 0 rg BT 165.69 233.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 212.05 233.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 245.10 233.10 Td (a ) Tj ET Q q 0 0 0 rg BT 252.04 233.10 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 297.29 233.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 319.79 233.10 Td (to ) Tj ET Q q 0 0 0 rg BT 330.07 233.10 Td (ensure ) Tj ET Q q 0 0 0 rg BT 358.67 233.10 Td (compliance ) Tj ET Q q 0 0 0 rg BT 407.26 233.10 Td (with ) Tj ET Q q 0 0 0 rg BT 427.54 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 442.25 233.10 Td (Consent.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.81 209.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 84.57 209.10 Td (as ) Tj ET Q q 0 0 0 rg BT 95.38 209.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 140.08 209.10 Td (disclosed, ) Tj ET Q q 0 0 0 rg BT 182.28 209.10 Td (in ) Tj ET Q q 0 0 0 rg BT 192.54 209.10 Td (October ) Tj ET Q q 0 0 0 rg BT 227.23 209.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 252.21 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 266.91 209.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 308.28 209.10 Td (reached ) Tj ET Q q 0 0 0 rg BT 341.84 209.10 Td (a ) Tj ET Q q 0 0 0 rg BT 348.76 209.10 Td (civil ) Tj ET Q q 0 0 0 rg BT 369.02 209.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 412.60 209.10 Td (with ) Tj ET Q q 0 0 0 rg BT 432.86 209.10 Td (the ) Tj ET Q q 0 0 0 rg BT 447.56 209.10 Td (SEC ) Tj ET Q q 0 0 0 rg BT 468.38 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 479.19 209.10 Td (alleged ) Tj ET Q q 0 0 0 rg BT 510.54 209.10 Td (FCP) Tj ET Q q 0 0 0 rg BT 527.42 209.10 Td (A) Tj ET Q q 0 0 0 rg BT 534.09 209.10 Td ( ) Tj ET Q q 0 0 0 rg BT 536.57 209.10 Td (violations ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.12 197.10 Td (which ) Tj ET Q q 0 0 0 rg BT 72.91 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 87.47 197.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 128.71 197.10 Td (agreed ) Tj ET Q q 0 0 0 rg BT 157.70 197.10 Td (to ) Tj ET Q q 0 0 0 rg BT 167.82 197.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 184.61 197.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 244.86 197.10 Td ($14.7 ) Tj ET Q q 0 0 0 rg BT 269.71 197.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.60 197.10 Td ( in ) Tj ET Q q 0 0 0 rg BT 311.23 197.10 Td (disgor) Tj ET Q q 0 0 0 rg BT 336.05 197.10 Td (gement, ) Tj ET Q q 0 0 0 rg BT 370.33 197.10 Td (penalties ) Tj ET Q q 0 0 0 rg BT 408.21 197.10 Td (and ) Tj ET Q q 0 0 0 rg BT 425.00 197.10 Td (interest.  ) Tj ET Q q 0 0 0 rg BT 461.26 197.10 Td (As ) Tj ET Q q 0 0 0 rg BT 474.72 197.10 Td (part ) Tj ET Q q 0 0 0 rg BT 492.61 197.10 Td (of ) Tj ET Q q 0 0 0 rg BT 503.29 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 517.85 197.10 Td (settlement, ) Tj ET Q q 0 0 0 rg BT 563.80 197.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 77.39 185.10 Td (agreed ) Tj ET Q q 0 0 0 rg BT 106.53 185.10 Td (to ) Tj ET Q q 0 0 0 rg BT 116.81 185.10 Td (a ) Tj ET Q q 0 0 0 rg BT 123.75 185.10 Td (two-year ) Tj ET Q q 0 0 0 rg BT 161.79 185.10 Td (self-monitoring ) Tj ET Q q 0 0 0 rg BT 226.50 185.10 Td (period ) Tj ET Q q 0 0 0 rg BT 254.54 185.10 Td (of ) Tj ET Q q 0 0 0 rg BT 265.38 185.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 304.53 185.10 Td (to ) Tj ET Q q 0 0 0 rg BT 314.81 185.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.53 185.10 Td (government ) Tj ET Q q 0 0 0 rg BT 379.79 185.10 Td (which ) Tj ET Q q 0 0 0 rg BT 406.73 185.10 Td (concluded ) Tj ET Q q 0 0 0 rg BT 450.32 185.10 Td (in ) Tj ET Q q 0 0 0 rg BT 460.60 185.10 Td (October ) Tj ET Q q 0 0 0 rg BT 495.31 185.10 Td (2017.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (Recently Issued ) Tj ET Q q 0 0 0 rg BT 104.89 161.10 Td (Accounting Standards) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.10 Td (For ) Tj ET Q q 0 0 0 rg BT 54.28 137.10 Td (recently ) Tj ET Q q 0 0 0 rg BT 90.86 137.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 120.25 137.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 168.50 137.10 Td (standards, ) Tj ET Q q 0 0 0 rg BT 213.16 137.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 236.41 137.10 Td (to ) Tj ET Q q 0 0 0 rg BT 248.57 137.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 275.72 137.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 287.60 137.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 329.20 137.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.90 137.10 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.90 137.10 Td (. ) Tj ET Q q 0 0 0 rg BT 417.82 137.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 468.86 137.10 Td (Policies—Recently ) Tj ET Q q 0 0 0 rg BT 550.45 137.10 Td (Issued ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 85.16 125.10 Td (Standards.”) Tj ET Q endstream endobj 95 0 obj <> endobj 96 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (47) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Critical ) Tj ET Q q 0 0 0 rg BT 70.71 749.25 Td (Accounting Policies) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.87 725.25 Td (preparation ) Tj ET Q q 0 0 0 rg BT 103.72 725.25 Td (of ) Tj ET Q q 0 0 0 rg BT 115.38 725.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 153.68 725.25 Td (statements ) Tj ET Q q 0 0 0 rg BT 199.22 725.25 Td (requires ) Tj ET Q q 0 0 0 rg BT 234.75 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 250.28 725.25 Td (use ) Tj ET Q q 0 0 0 rg BT 266.94 725.25 Td (of ) Tj ET Q q 0 0 0 rg BT 278.59 725.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 319.13 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 336.89 725.25 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 389.66 725.25 Td (that ) Tj ET Q q 0 0 0 rg BT 407.98 725.25 Td (af) Tj ET Q q 0 0 0 rg BT 415.56 725.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 433.87 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 449.41 725.25 Td (reported ) Tj ET Q q 0 0 0 rg BT 486.05 725.25 Td (amounts ) Tj ET Q q 0 0 0 rg BT 523.26 725.25 Td (of ) Tj ET Q q 0 0 0 rg BT 534.91 725.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 561.56 725.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 76.48 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 94.19 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 109.67 713.25 Td (reported ) Tj ET Q q 0 0 0 rg BT 146.25 713.25 Td (amounts ) Tj ET Q q 0 0 0 rg BT 183.41 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 195.00 713.25 Td (revenue ) Tj ET Q q 0 0 0 rg BT 229.92 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 247.62 713.25 Td (expenses. ) Tj ET Q q 0 0 0 rg BT 289.49 713.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 308.30 713.25 Td (critical ) Tj ET Q q 0 0 0 rg BT 339.33 713.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 386.47 713.25 Td (policies ) Tj ET Q q 0 0 0 rg BT 420.84 713.25 Td (are ) Tj ET Q q 0 0 0 rg BT 436.31 713.25 Td (those ) Tj ET Q q 0 0 0 rg BT 460.69 713.25 Td (that ) Tj ET Q q 0 0 0 rg BT 478.95 713.25 Td (significantly ) Tj ET Q q 0 0 0 rg BT 532.21 713.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 562.68 713.25 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 73.14 701.25 Td (condition ) Tj ET Q q 0 0 0 rg BT 113.07 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 129.67 701.25 Td (results ) Tj ET Q q 0 0 0 rg BT 157.94 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 168.43 701.25 Td (operations ) Tj ET Q q 0 0 0 rg BT 212.24 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 228.84 701.25 Td (require ) Tj ET Q q 0 0 0 rg BT 259.32 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 273.69 701.25 Td (most ) Tj ET Q q 0 0 0 rg BT 295.30 701.25 Td (dif) Tj ET Q q 0 0 0 rg BT 306.23 701.25 Td (ficult, ) Tj ET Q q 0 0 0 rg BT 331.99 701.25 Td (subjective ) Tj ET Q q 0 0 0 rg BT 374.69 701.25 Td (or ) Tj ET Q q 0 0 0 rg BT 385.18 701.25 Td (complex ) Tj ET Q q 0 0 0 rg BT 421.78 701.25 Td (judgments, ) Tj ET Q q 0 0 0 rg BT 468.10 701.25 Td (often ) Tj ET Q q 0 0 0 rg BT 490.81 701.25 Td (as ) Tj ET Q q 0 0 0 rg BT 501.30 701.25 Td (a ) Tj ET Q q 0 0 0 rg BT 507.90 701.25 Td (result ) Tj ET Q q 0 0 0 rg BT 532.27 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 542.76 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 557.14 701.25 Td (need ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (to ) Tj ET Q q 0 0 0 rg BT 45.84 689.25 Td (make ) Tj ET Q q 0 0 0 rg BT 69.55 689.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 108.83 689.25 Td (about ) Tj ET Q q 0 0 0 rg BT 133.10 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 147.38 689.25 Td (ef) Tj ET Q q 0 0 0 rg BT 154.97 689.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 172.02 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 182.41 689.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 213.90 689.25 Td (that ) Tj ET Q q 0 0 0 rg BT 230.96 689.25 Td (are ) Tj ET Q q 0 0 0 rg BT 245.22 689.25 Td (inherently ) Tj ET Q q 0 0 0 rg BT 287.83 689.25 Td (uncertain. ) Tj ET Q q 0 0 0 rg BT 329.59 689.25 Td (Because ) Tj ET Q q 0 0 0 rg BT 364.96 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 375.36 689.25 Td (this ) Tj ET Q q 0 0 0 rg BT 391.86 689.25 Td (uncertainty) Tj ET Q q 0 0 0 rg BT 436.20 689.25 Td (, ) Tj ET Q q 0 0 0 rg BT 440.76 689.25 Td (actual ) Tj ET Q q 0 0 0 rg BT 466.69 689.25 Td (results ) Tj ET Q q 0 0 0 rg BT 494.86 689.25 Td (may ) Tj ET Q q 0 0 0 rg BT 514.13 689.25 Td (vary ) Tj ET Q q 0 0 0 rg BT 533.96 689.25 Td (from ) Tj ET Q q 0 0 0 rg BT 555.46 689.25 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (estimates.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (Revenue Recognition) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.44 629.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 101.20 629.25 Td (policy ) Tj ET Q q 0 0 0 rg BT 129.09 629.25 Td (for ) Tj ET Q q 0 0 0 rg BT 143.64 629.25 Td (revenue ) Tj ET Q q 0 0 0 rg BT 178.17 629.25 Td (recognition ) Tj ET Q q 0 0 0 rg BT 226.60 629.25 Td (has ) Tj ET Q q 0 0 0 rg BT 242.82 629.25 Td (a ) Tj ET Q q 0 0 0 rg BT 250.15 629.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 295.82 629.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 325.92 629.25 Td (on ) Tj ET Q q 0 0 0 rg BT 338.81 629.25 Td (reported ) Tj ET Q q 0 0 0 rg BT 375.01 629.25 Td (results ) Tj ET Q q 0 0 0 rg BT 404.01 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 421.34 629.25 Td (relies ) Tj ET Q q 0 0 0 rg BT 445.88 629.25 Td (on ) Tj ET Q q 0 0 0 rg BT 458.77 629.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 488.86 629.25 Td (estimates. ) Tj ET Q q 0 0 0 rg BT 531.47 629.25 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 569.34 629.25 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 81.51 617.25 Td (when ) Tj ET Q q 0 0 0 rg BT 104.82 617.25 Td (persuasive ) Tj ET Q q 0 0 0 rg BT 148.67 617.25 Td (evidence ) Tj ET Q q 0 0 0 rg BT 185.85 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 195.83 617.25 Td (an ) Tj ET Q q 0 0 0 rg BT 206.92 617.25 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 258.54 617.25 Td (exists, ) Tj ET Q q 0 0 0 rg BT 285.46 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 299.33 617.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 320.41 617.25 Td (price ) Tj ET Q q 0 0 0 rg BT 342.05 617.25 Td (is ) Tj ET Q q 0 0 0 rg BT 350.37 617.25 Td (fixed ) Tj ET Q q 0 0 0 rg BT 372.56 617.25 Td (or ) Tj ET Q q 0 0 0 rg BT 382.54 617.25 Td (determinable, ) Tj ET Q q 0 0 0 rg BT 438.88 617.25 Td (collectability ) Tj ET Q q 0 0 0 rg BT 492.73 617.25 Td (is ) Tj ET Q q 0 0 0 rg BT 501.05 617.25 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 546.01 617.25 Td (assured ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.72 605.25 Td (title ) Tj ET Q q 0 0 0 rg BT 72.56 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 90.29 605.25 Td (substantially ) Tj ET Q q 0 0 0 rg BT 144.13 605.25 Td (all ) Tj ET Q q 0 0 0 rg BT 157.41 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 169.02 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 184.53 605.25 Td (risks ) Tj ET Q q 0 0 0 rg BT 206.70 605.25 Td (and ) Tj ET Q q 0 0 0 rg BT 224.43 605.25 Td (rewards ) Tj ET Q q 0 0 0 rg BT 259.36 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 270.98 605.25 Td (ownership ) Tj ET Q q 0 0 0 rg BT 315.93 605.25 Td (have ) Tj ET Q q 0 0 0 rg BT 338.09 605.25 Td (transferred ) Tj ET Q q 0 0 0 rg BT 384.68 605.25 Td (\(generally ) Tj ET Q q 0 0 0 rg BT 428.50 605.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 451.79 605.25 Td (shipment ) Tj ET Q q 0 0 0 rg BT 491.74 605.25 Td (except ) Tj ET Q q 0 0 0 rg BT 521.12 605.25 Td (in ) Tj ET Q q 0 0 0 rg BT 532.18 605.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 562.67 605.25 Td (EU ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 69.32 593.25 Td (which ) Tj ET Q q 0 0 0 rg BT 95.41 593.25 Td (does ) Tj ET Q q 0 0 0 rg BT 115.40 593.25 Td (not ) Tj ET Q q 0 0 0 rg BT 129.84 593.25 Td (occur ) Tj ET Q q 0 0 0 rg BT 153.71 593.25 Td (until ) Tj ET Q q 0 0 0 rg BT 173.71 593.25 Td (delivery ) Tj ET Q q 0 0 0 rg BT 208.13 593.25 Td (of ) Tj ET Q q 0 0 0 rg BT 218.12 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 232.00 593.25 Td (products ) Tj ET Q q 0 0 0 rg BT 268.09 593.25 Td (to ) Tj ET Q q 0 0 0 rg BT 277.53 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 291.41 593.25 Td (customer\). ) Tj ET Q q 0 0 0 rg BT 335.56 593.25 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 372.20 593.25 Td (is ) Tj ET Q q 0 0 0 rg BT 380.53 593.25 Td (also ) Tj ET Q q 0 0 0 rg BT 398.30 593.25 Td (reduced ) Tj ET Q q 0 0 0 rg BT 431.61 593.25 Td (for ) Tj ET Q q 0 0 0 rg BT 444.93 593.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 467.14 593.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 488.24 593.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 537.67 593.25 Td (discussed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (below) Tj ET Q q 0 0 0 rg BT 59.79 581.25 Td (, ) Tj ET Q q 0 0 0 rg BT 64.53 581.25 Td (all ) Tj ET Q q 0 0 0 rg BT 76.76 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 87.33 581.25 Td (which ) Tj ET Q q 0 0 0 rg BT 114.00 581.25 Td (involve ) Tj ET Q q 0 0 0 rg BT 146.24 581.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 190.69 581.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 230.14 581.25 Td (and ) Tj ET Q q 0 0 0 rg BT 246.81 581.25 Td (judgment ) Tj ET Q q 0 0 0 rg BT 286.82 581.25 Td (after ) Tj ET Q q 0 0 0 rg BT 307.38 581.25 Td (considering ) Tj ET Q q 0 0 0 rg BT 356.27 581.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 377.94 581.25 Td (interpretations ) Tj ET Q q 0 0 0 rg BT 437.94 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 448.51 581.25 Td (applicable ) Tj ET Q q 0 0 0 rg BT 491.83 581.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 512.40 581.25 Td (and ) Tj ET Q q 0 0 0 rg BT 529.08 581.25 Td (regulations, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (historical ) Tj ET Q q 0 0 0 rg BT 75.29 569.25 Td (experience, ) Tj ET Q q 0 0 0 rg BT 123.17 569.25 Td (payer ) Tj ET Q q 0 0 0 rg BT 147.46 569.25 Td (channel ) Tj ET Q q 0 0 0 rg BT 180.63 569.25 Td (mix ) Tj ET Q q 0 0 0 rg BT 198.27 569.25 Td (\(e.g. ) Tj ET Q q 0 0 0 rg BT 218.12 569.25 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 257.95 569.25 Td (or ) Tj ET Q q 0 0 0 rg BT 268.36 569.25 Td (Medicaid\), ) Tj ET Q q 0 0 0 rg BT 314.04 569.25 Td (current ) Tj ET Q q 0 0 0 rg BT 344.43 569.25 Td (contract ) Tj ET Q q 0 0 0 rg BT 378.71 569.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 404.67 569.25 Td (under ) Tj ET Q q 0 0 0 rg BT 429.52 569.25 Td (applicable ) Tj ET Q q 0 0 0 rg BT 472.69 569.25 Td (programs, ) Tj ET Q q 0 0 0 rg BT 515.04 569.25 Td (unbilled ) Tj ET Q q 0 0 0 rg BT 549.89 569.25 Td (claims ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.79 557.25 Td (processing ) Tj ET Q q 0 0 0 rg BT 97.92 557.25 Td (time ) Tj ET Q q 0 0 0 rg BT 118.05 557.25 Td (lags ) Tj ET Q q 0 0 0 rg BT 136.51 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 153.30 557.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 193.98 557.25 Td (levels ) Tj ET Q q 0 0 0 rg BT 219.66 557.25 Td (in ) Tj ET Q q 0 0 0 rg BT 229.80 557.25 Td (the ) Tj ET Q q 0 0 0 rg BT 244.37 557.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 292.84 557.25 Td (channel. ) Tj ET Q q 0 0 0 rg BT 328.78 557.25 Td (Estimates ) Tj ET Q q 0 0 0 rg BT 370.02 557.25 Td (are ) Tj ET Q q 0 0 0 rg BT 384.58 557.25 Td (assessed ) Tj ET Q q 0 0 0 rg BT 420.82 557.25 Td (each ) Tj ET Q q 0 0 0 rg BT 441.49 557.25 Td (period ) Tj ET Q q 0 0 0 rg BT 469.39 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 486.19 557.25 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 521.87 557.25 Td (as ) Tj ET Q q 0 0 0 rg BT 532.55 557.25 Td (required ) Tj ET Q q 0 0 0 rg BT 568.22 557.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (revise ) Tj ET Q q 0 0 0 rg BT 62.38 545.25 Td (information ) Tj ET Q q 0 0 0 rg BT 112.09 545.25 Td (or ) Tj ET Q q 0 0 0 rg BT 122.92 545.25 Td (actual ) Tj ET Q q 0 0 0 rg BT 149.29 545.25 Td (experience. ) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 58.68 521.25 Td (Adjustments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td (The ) Tj ET Q q 0 0 0 rg BT 53.85 497.25 Td (following ) Tj ET Q q 0 0 0 rg BT 95.05 497.25 Td (categories ) Tj ET Q q 0 0 0 rg BT 137.88 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 148.52 497.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 171.38 497.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 221.46 497.25 Td (involve ) Tj ET Q q 0 0 0 rg BT 253.76 497.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 298.28 497.25 Td (estimates, ) Tj ET Q q 0 0 0 rg BT 340.30 497.25 Td (judgments ) Tj ET Q q 0 0 0 rg BT 384.27 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 401.01 497.25 Td (information ) Tj ET Q q 0 0 0 rg BT 450.53 497.25 Td (obtained ) Tj ET Q q 0 0 0 rg BT 487.27 497.25 Td (from ) Tj ET Q q 0 0 0 rg BT 509.01 497.25 Td (external ) Tj ET Q q 0 0 0 rg BT 543.52 497.25 Td (sources. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 60.71 485.25 Td (to ) Tj ET Q q 0 0 0 rg BT 70.99 485.25 Td (“—T) Tj ET Q q 0 0 0 rg BT 90.83 485.25 Td (otal ) Tj ET Q q 0 0 0 rg BT 108.33 485.25 Td (Revenues” ) Tj ET Q q 0 0 0 rg BT 154.14 485.25 Td (for ) Tj ET Q q 0 0 0 rg BT 168.30 485.25 Td (further ) Tj ET Q q 0 0 0 rg BT 198.01 485.25 Td (discussion ) Tj ET Q q 0 0 0 rg BT 242.18 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 259.12 485.25 Td (analysis ) Tj ET Q q 0 0 0 rg BT 293.84 485.25 Td (of ) Tj ET Q q 0 0 0 rg BT 304.67 485.25 Td (each ) Tj ET Q q 0 0 0 rg BT 325.48 485.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 370.19 485.25 Td (category ) Tj ET Q q 0 0 0 rg BT 407.12 485.25 Td (of ) Tj ET Q q 0 0 0 rg BT 417.95 485.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 441.00 485.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 462.94 485.25 Td (adjustments.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 459.9169921875 m 170.3359375 459.9169921875 l s q 0 0 0 rg BT 36.00 461.25 Td (Char) Tj ET Q q 0 0 0 rg BT 56.19 461.25 Td (ge-backs and cash discounts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.03 437.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 74.29 437.25 Td (business ) Tj ET Q q 0 0 0 rg BT 110.66 437.25 Td (participates ) Tj ET Q q 0 0 0 rg BT 159.23 437.25 Td (in ) Tj ET Q q 0 0 0 rg BT 169.48 437.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 209.73 437.25 Td (with ) Tj ET Q q 0 0 0 rg BT 229.99 437.25 Td (government ) Tj ET Q q 0 0 0 rg BT 280.23 437.25 Td (entities, ) Tj ET Q q 0 0 0 rg BT 314.09 437.25 Td (the ) Tj ET Q q 0 0 0 rg BT 328.78 437.25 Td (most ) Tj ET Q q 0 0 0 rg BT 350.71 437.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 395.40 437.25 Td (of ) Tj ET Q q 0 0 0 rg BT 406.21 437.25 Td (which ) Tj ET Q q 0 0 0 rg BT 433.12 437.25 Td (are ) Tj ET Q q 0 0 0 rg BT 447.81 437.25 Td (the ) Tj ET Q q 0 0 0 rg BT 462.50 437.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 482.77 437.25 Td (Department ) Tj ET Q q 0 0 0 rg BT 532.45 437.25 Td (of ) Tj ET Q q 0 0 0 rg BT 543.25 437.25 Td (Defense ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.31 425.25 Td (the ) Tj ET Q q 0 0 0 rg BT 66.41 425.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 86.06 425.25 Td (Department ) Tj ET Q q 0 0 0 rg BT 135.14 425.25 Td (of ) Tj ET Q q 0 0 0 rg BT 145.21 425.25 Td (V) Tj ET Q q 0 0 0 rg BT 151.32 425.25 Td (eterans ) Tj ET Q q 0 0 0 rg BT 181.10 425.25 Td (Af) Tj ET Q q 0 0 0 rg BT 191.47 425.25 Td (fairs, ) Tj ET Q q 0 0 0 rg BT 213.62 425.25 Td (and ) Tj ET Q q 0 0 0 rg BT 229.93 425.25 Td (other ) Tj ET Q q 0 0 0 rg BT 252.35 425.25 Td (parties, ) Tj ET Q q 0 0 0 rg BT 283.38 425.25 Td (including ) Tj ET Q q 0 0 0 rg BT 323.03 425.25 Td (covered ) Tj ET Q q 0 0 0 rg BT 356.55 425.25 Td (entities ) Tj ET Q q 0 0 0 rg BT 387.31 425.25 Td (under ) Tj ET Q q 0 0 0 rg BT 411.95 425.25 Td (the ) Tj ET Q q 0 0 0 rg BT 426.04 425.25 Td (340B ) Tj ET Q q 0 0 0 rg BT 449.59 425.25 Td (Drug ) Tj ET Q q 0 0 0 rg BT 472.01 425.25 Td (Pricing ) Tj ET Q q 0 0 0 rg BT 502.78 425.25 Td (Program, ) Tj ET Q q 0 0 0 rg BT 541.59 425.25 Td (whereby ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 66.32 413.25 Td (on ) Tj ET Q q 0 0 0 rg BT 78.31 413.25 Td (products ) Tj ET Q q 0 0 0 rg BT 114.75 413.25 Td (is ) Tj ET Q q 0 0 0 rg BT 123.41 413.25 Td (extended ) Tj ET Q q 0 0 0 rg BT 161.50 413.25 Td (below ) Tj ET Q q 0 0 0 rg BT 187.93 413.25 Td (wholesaler ) Tj ET Q q 0 0 0 rg BT 233.24 413.25 Td (list ) Tj ET Q q 0 0 0 rg BT 247.46 413.25 Td (price ) Tj ET Q q 0 0 0 rg BT 269.44 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 279.22 413.25 Td (participating ) Tj ET Q q 0 0 0 rg BT 331.75 413.25 Td (entities. ) Tj ET Q q 0 0 0 rg BT 364.98 413.25 Td (These ) Tj ET Q q 0 0 0 rg BT 390.85 413.25 Td (entities ) Tj ET Q q 0 0 0 rg BT 421.73 413.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 459.26 413.25 Td (products ) Tj ET Q q 0 0 0 rg BT 495.69 413.25 Td (through ) Tj ET Q q 0 0 0 rg BT 528.80 413.25 Td (wholesalers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (at ) Tj ET Q q 0 0 0 rg BT 45.48 401.25 Td (the ) Tj ET Q q 0 0 0 rg BT 59.96 401.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 84.99 401.25 Td (program ) Tj ET Q q 0 0 0 rg BT 121.13 401.25 Td (price ) Tj ET Q q 0 0 0 rg BT 143.38 401.25 Td (and ) Tj ET Q q 0 0 0 rg BT 160.08 401.25 Td (the ) Tj ET Q q 0 0 0 rg BT 174.56 401.25 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 224.03 401.25 Td (then ) Tj ET Q q 0 0 0 rg BT 243.51 401.25 Td (char) Tj ET Q q 0 0 0 rg BT 260.54 401.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 272.24 401.25 Td (us ) Tj ET Q q 0 0 0 rg BT 283.40 401.25 Td (the ) Tj ET Q q 0 0 0 rg BT 297.88 401.25 Td (dif) Tj ET Q q 0 0 0 rg BT 308.80 401.25 Td (ference ) Tj ET Q q 0 0 0 rg BT 340.48 401.25 Td (between ) Tj ET Q q 0 0 0 rg BT 376.06 401.25 Td (their ) Tj ET Q q 0 0 0 rg BT 396.65 401.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 442.79 401.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 461.16 401.25 Td (and ) Tj ET Q q 0 0 0 rg BT 477.87 401.25 Td (the ) Tj ET Q q 0 0 0 rg BT 492.35 401.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 517.38 401.25 Td (program ) Tj ET Q q 0 0 0 rg BT 553.52 401.25 Td (price. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (Accounts ) Tj ET Q q 0 0 0 rg BT 75.95 389.25 Td (receivable ) Tj ET Q q 0 0 0 rg BT 119.22 389.25 Td (is ) Tj ET Q q 0 0 0 rg BT 128.07 389.25 Td (reduced ) Tj ET Q q 0 0 0 rg BT 161.90 389.25 Td (for ) Tj ET Q q 0 0 0 rg BT 175.74 389.25 Td (the ) Tj ET Q q 0 0 0 rg BT 190.14 389.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 230.65 389.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 262.83 389.25 Td (of ) Tj ET Q q 0 0 0 rg BT 273.34 389.25 Td (unprocessed ) Tj ET Q q 0 0 0 rg BT 324.96 389.25 Td (char) Tj ET Q q 0 0 0 rg BT 341.98 389.25 Td (ge-back ) Tj ET Q q 0 0 0 rg BT 375.81 389.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 404.10 389.25 Td (attributable ) Tj ET Q q 0 0 0 rg BT 451.82 389.25 Td (to ) Tj ET Q q 0 0 0 rg BT 461.78 389.25 Td (a ) Tj ET Q q 0 0 0 rg BT 468.40 389.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 486.14 389.25 Td (\(typically ) Tj ET Q q 0 0 0 rg BT 526.64 389.25 Td (within ) Tj ET Q q 0 0 0 rg BT 554.38 389.25 Td (a ) Tj ET Q q 0 0 0 rg BT 561.00 389.25 Td (two ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.25 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 377.25 Td (four ) Tj ET Q q 0 0 0 rg BT 65.44 377.25 Td (week ) Tj ET Q q 0 0 0 rg BT 89.04 377.25 Td (time ) Tj ET Q q 0 0 0 rg BT 109.31 377.25 Td (lag\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.25 Td (In ) Tj ET Q q 0 0 0 rg BT 47.07 353.25 Td (the ) Tj ET Q q 0 0 0 rg BT 62.03 353.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 82.55 353.25 Td (and ) Tj ET Q q 0 0 0 rg BT 99.73 353.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 129.67 353.25 Td (other ) Tj ET Q q 0 0 0 rg BT 152.96 353.25 Td (countries, ) Tj ET Q q 0 0 0 rg BT 194.86 353.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 215.37 353.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 255.89 353.25 Td (are ) Tj ET Q q 0 0 0 rg BT 270.83 353.25 Td (of) Tj ET Q q 0 0 0 rg BT 278.98 353.25 Td (fered ) Tj ET Q q 0 0 0 rg BT 302.26 353.25 Td (as ) Tj ET Q q 0 0 0 rg BT 313.33 353.25 Td (an ) Tj ET Q q 0 0 0 rg BT 325.51 353.25 Td (incentive ) Tj ET Q q 0 0 0 rg BT 364.90 353.25 Td (for ) Tj ET Q q 0 0 0 rg BT 379.30 353.25 Td (prompt ) Tj ET Q q 0 0 0 rg BT 410.93 353.25 Td (payment, ) Tj ET Q q 0 0 0 rg BT 450.60 353.25 Td (generally ) Tj ET Q q 0 0 0 rg BT 490.55 353.25 Td (approximating ) Tj ET Q q 0 0 0 rg BT 551.61 353.25 Td (2% ) Tj ET Q q 0 0 0 rg BT 567.68 353.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.14 341.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 73.50 341.25 Td (price. ) Tj ET Q q 0 0 0 rg BT 98.27 341.25 Td (Accounts ) Tj ET Q q 0 0 0 rg BT 138.96 341.25 Td (receivable ) Tj ET Q q 0 0 0 rg BT 182.96 341.25 Td (is ) Tj ET Q q 0 0 0 rg BT 192.56 341.25 Td (reduced ) Tj ET Q q 0 0 0 rg BT 227.13 341.25 Td (for ) Tj ET Q q 0 0 0 rg BT 241.71 341.25 Td (the ) Tj ET Q q 0 0 0 rg BT 256.85 341.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 298.09 341.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 331.01 341.25 Td (of ) Tj ET Q q 0 0 0 rg BT 342.27 341.25 Td (unprocessed ) Tj ET Q q 0 0 0 rg BT 394.62 341.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 415.31 341.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 456.01 341.25 Td (\(typically ) Tj ET Q q 0 0 0 rg BT 497.26 341.25 Td (within ) Tj ET Q q 0 0 0 rg BT 525.74 341.25 Td (a ) Tj ET Q q 0 0 0 rg BT 533.10 341.25 Td (one ) Tj ET Q q 0 0 0 rg BT 550.46 341.25 Td (month ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.25 Td (time ) Tj ET Q q 0 0 0 rg BT 56.27 329.25 Td (lag\).) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 303.9169921875 m 163.275390625 303.9169921875 l s q 0 0 0 rg BT 36.00 305.25 Td (Medicaid and Medicar) Tj ET Q q 0 0 0 rg BT 127.27 305.25 Td (e r) Tj ET Q q 0 0 0 rg BT 137.73 305.25 Td (ebates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.25 Td (Our ) Tj ET Q q 0 0 0 rg BT 54.86 281.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 75.95 281.25 Td (business ) Tj ET Q q 0 0 0 rg BT 113.15 281.25 Td (participates ) Tj ET Q q 0 0 0 rg BT 162.55 281.25 Td (in ) Tj ET Q q 0 0 0 rg BT 173.63 281.25 Td (state ) Tj ET Q q 0 0 0 rg BT 195.27 281.25 Td (government ) Tj ET Q q 0 0 0 rg BT 246.34 281.25 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 287.41 281.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 328.49 281.25 Td (and ) Tj ET Q q 0 0 0 rg BT 346.23 281.25 Td (other ) Tj ET Q q 0 0 0 rg BT 370.09 281.25 Td (qualifying ) Tj ET Q q 0 0 0 rg BT 414.50 281.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 447.79 281.25 Td (and ) Tj ET Q q 0 0 0 rg BT 465.54 281.25 Td (state ) Tj ET Q q 0 0 0 rg BT 487.17 281.25 Td (government ) Tj ET Q q 0 0 0 rg BT 538.25 281.25 Td (programs ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.25 Td (requiring ) Tj ET Q q 0 0 0 rg BT 75.79 269.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 116.71 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 134.28 269.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 165.74 269.25 Td (to ) Tj ET Q q 0 0 0 rg BT 176.65 269.25 Td (participating ) Tj ET Q q 0 0 0 rg BT 230.33 269.25 Td (state ) Tj ET Q q 0 0 0 rg BT 251.79 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 269.36 269.25 Td (local ) Tj ET Q q 0 0 0 rg BT 291.94 269.25 Td (government ) Tj ET Q q 0 0 0 rg BT 342.84 269.25 Td (entities. ) Tj ET Q q 0 0 0 rg BT 376.66 269.25 Td (All ) Tj ET Q q 0 0 0 rg BT 392.58 269.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 433.49 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 451.07 269.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 482.52 269.25 Td (provided ) Tj ET Q q 0 0 0 rg BT 521.21 269.25 Td (through ) Tj ET Q q 0 0 0 rg BT 555.45 269.25 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 76.66 257.25 Td (are ) Tj ET Q q 0 0 0 rg BT 91.76 257.25 Td (included ) Tj ET Q q 0 0 0 rg BT 129.09 257.25 Td (in ) Tj ET Q q 0 0 0 rg BT 139.76 257.25 Td (our ) Tj ET Q q 0 0 0 rg BT 155.98 257.25 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 196.63 257.25 Td (rebate ) Tj ET Q q 0 0 0 rg BT 223.95 257.25 Td (accrual. ) Tj ET Q q 0 0 0 rg BT 258.20 257.25 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 298.86 257.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 330.07 257.25 Td (have ) Tj ET Q q 0 0 0 rg BT 351.84 257.25 Td (also ) Tj ET Q q 0 0 0 rg BT 370.84 257.25 Td (been ) Tj ET Q q 0 0 0 rg BT 392.61 257.25 Td (extended ) Tj ET Q q 0 0 0 rg BT 431.59 257.25 Td (to ) Tj ET Q q 0 0 0 rg BT 442.26 257.25 Td (drugs ) Tj ET Q q 0 0 0 rg BT 467.38 257.25 Td (used ) Tj ET Q q 0 0 0 rg BT 488.60 257.25 Td (in ) Tj ET Q q 0 0 0 rg BT 499.27 257.25 Td (managed ) Tj ET Q q 0 0 0 rg BT 538.25 257.25 Td (Medicaid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.25 Td (plans. ) Tj ET Q q 0 0 0 rg BT 61.93 245.25 Td (The ) Tj ET Q q 0 0 0 rg BT 79.97 245.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 120.79 245.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 153.29 245.25 Td (of ) Tj ET Q q 0 0 0 rg BT 164.12 245.25 Td (unpaid ) Tj ET Q q 0 0 0 rg BT 193.84 245.25 Td (or ) Tj ET Q q 0 0 0 rg BT 204.67 245.25 Td (unbilled ) Tj ET Q q 0 0 0 rg BT 239.94 245.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 270.76 245.25 Td (is ) Tj ET Q q 0 0 0 rg BT 279.93 245.25 Td (presented ) Tj ET Q q 0 0 0 rg BT 320.74 245.25 Td (as ) Tj ET Q q 0 0 0 rg BT 331.57 245.25 Td (a ) Tj ET Q q 0 0 0 rg BT 338.51 245.25 Td (liability) Tj ET Q q 0 0 0 rg BT 368.97 245.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.25 Td (Rebates ) Tj ET Q q 0 0 0 rg BT 70.20 221.25 Td (and ) Tj ET Q q 0 0 0 rg BT 87.19 221.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 127.52 221.25 Td (are ) Tj ET Q q 0 0 0 rg BT 142.27 221.25 Td (of) Tj ET Q q 0 0 0 rg BT 150.42 221.25 Td (fered ) Tj ET Q q 0 0 0 rg BT 173.51 221.25 Td (to ) Tj ET Q q 0 0 0 rg BT 183.84 221.25 Td (managed ) Tj ET Q q 0 0 0 rg BT 222.48 221.25 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 266.11 221.25 Td (or) Tj ET Q q 0 0 0 rg BT 274.26 221.25 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 322.35 221.25 Td (in ) Tj ET Q q 0 0 0 rg BT 332.67 221.25 Td (the ) Tj ET Q q 0 0 0 rg BT 347.44 221.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 367.77 221.25 Td (managing ) Tj ET Q q 0 0 0 rg BT 409.75 221.25 Td (prescription ) Tj ET Q q 0 0 0 rg BT 460.07 221.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 480.95 221.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 521.26 221.25 Td (and ) Tj ET Q q 0 0 0 rg BT 538.25 221.25 Td (Medicare ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.25 Td (Advantage ) Tj ET Q q 0 0 0 rg BT 81.35 209.25 Td (prescription ) Tj ET Q q 0 0 0 rg BT 131.15 209.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 151.51 209.25 Td (plans ) Tj ET Q q 0 0 0 rg BT 174.65 209.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 211.67 209.25 Td (the ) Tj ET Q q 0 0 0 rg BT 225.92 209.25 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 265.71 209.25 Td (Part ) Tj ET Q q 0 0 0 rg BT 283.85 209.25 Td (D ) Tj ET Q q 0 0 0 rg BT 293.11 209.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 313.47 209.25 Td (benefit. ) Tj ET Q q 0 0 0 rg BT 345.62 209.25 Td (W) Tj ET Q q 0 0 0 rg BT 354.26 209.25 Td (e ) Tj ET Q q 0 0 0 rg BT 360.73 209.25 Td (also ) Tj ET Q q 0 0 0 rg BT 378.87 209.25 Td (pay ) Tj ET Q q 0 0 0 rg BT 395.35 209.25 Td (a ) Tj ET Q q 0 0 0 rg BT 401.82 209.25 Td (50% ) Tj ET Q q 0 0 0 rg BT 422.18 209.25 Td (point ) Tj ET Q q 0 0 0 rg BT 444.77 209.25 Td (of ) Tj ET Q q 0 0 0 rg BT 455.14 209.25 Td (service ) Tj ET Q q 0 0 0 rg BT 485.48 209.25 Td (discount ) Tj ET Q q 0 0 0 rg BT 521.40 209.25 Td (to ) Tj ET Q q 0 0 0 rg BT 531.22 209.25 Td (the ) Tj ET Q q 0 0 0 rg BT 545.47 209.25 Td (Centers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.25 Td (for ) Tj ET Q q 0 0 0 rg BT 49.73 197.25 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 89.55 197.25 Td (& ) Tj ET Q q 0 0 0 rg BT 99.40 197.25 Td (Medicaid ) Tj ET Q q 0 0 0 rg BT 139.23 197.25 Td (Services ) Tj ET Q q 0 0 0 rg BT 175.18 197.25 Td (when ) Tj ET Q q 0 0 0 rg BT 198.91 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 213.20 197.25 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 253.02 197.25 Td (Part ) Tj ET Q q 0 0 0 rg BT 271.20 197.25 Td (D ) Tj ET Q q 0 0 0 rg BT 280.49 197.25 Td (beneficiaries ) Tj ET Q q 0 0 0 rg BT 333.64 197.25 Td (are ) Tj ET Q q 0 0 0 rg BT 347.91 197.25 Td (in ) Tj ET Q q 0 0 0 rg BT 357.76 197.25 Td (the ) Tj ET Q q 0 0 0 rg BT 372.05 197.25 Td (coverage ) Tj ET Q q 0 0 0 rg BT 410.20 197.25 Td (gap ) Tj ET Q q 0 0 0 rg BT 426.71 197.25 Td (\("donut ) Tj ET Q q 0 0 0 rg BT 458.97 197.25 Td (hole"\). ) Tj ET Q q 0 0 0 rg BT 488.02 197.25 Td (The ) Tj ET Q q 0 0 0 rg BT 505.63 197.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 546.02 197.25 Td (amount ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.83 185.25 Td (unpaid ) Tj ET Q q 0 0 0 rg BT 76.55 185.25 Td (or ) Tj ET Q q 0 0 0 rg BT 87.38 185.25 Td (unbilled ) Tj ET Q q 0 0 0 rg BT 122.65 185.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 153.47 185.25 Td (and ) Tj ET Q q 0 0 0 rg BT 170.40 185.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 210.68 185.25 Td (is ) Tj ET Q q 0 0 0 rg BT 219.85 185.25 Td (presented ) Tj ET Q q 0 0 0 rg BT 260.67 185.25 Td (as ) Tj ET Q q 0 0 0 rg BT 271.50 185.25 Td (a ) Tj ET Q q 0 0 0 rg BT 278.44 185.25 Td (liability) Tj ET Q q 0 0 0 rg BT 308.90 185.25 Td (. ) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 159.9169921875 m 234.974609375 159.9169921875 l s q 0 0 0 rg BT 36.00 161.25 Td (Other r) Tj ET Q q 0 0 0 rg BT 65.35 161.25 Td (ebates, r) Tj ET Q q 0 0 0 rg BT 99.42 161.25 Td (eturns, discounts and adjustments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.25 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.32 137.25 Td (GTN ) Tj ET Q q 0 0 0 rg BT 84.42 137.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 106.41 137.25 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 156.74 137.25 Td (include ) Tj ET Q q 0 0 0 rg BT 188.72 137.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 210.71 137.25 Td (returns ) Tj ET Q q 0 0 0 rg BT 241.03 137.25 Td (and ) Tj ET Q q 0 0 0 rg BT 258.02 137.25 Td (all ) Tj ET Q q 0 0 0 rg BT 270.57 137.25 Td (other ) Tj ET Q q 0 0 0 rg BT 293.67 137.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 333.99 137.25 Td (based ) Tj ET Q q 0 0 0 rg BT 359.31 137.25 Td (on ) Tj ET Q q 0 0 0 rg BT 371.86 137.25 Td (applicable ) Tj ET Q q 0 0 0 rg BT 415.50 137.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 436.38 137.25 Td (and ) Tj ET Q q 0 0 0 rg BT 453.37 137.25 Td (regulations ) Tj ET Q q 0 0 0 rg BT 500.35 137.25 Td (for ) Tj ET Q q 0 0 0 rg BT 514.56 137.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 557.67 137.25 Td (non-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 55.57 125.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 94.02 125.25 Td (as ) Tj ET Q q 0 0 0 rg BT 104.14 125.25 Td (well ) Tj ET Q q 0 0 0 rg BT 123.15 125.25 Td (as ) Tj ET Q q 0 0 0 rg BT 133.27 125.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 163.38 125.25 Td (of) Tj ET Q q 0 0 0 rg BT 171.53 125.25 Td (fered ) Tj ET Q q 0 0 0 rg BT 193.85 125.25 Td (to ) Tj ET Q q 0 0 0 rg BT 203.42 125.25 Td (managed ) Tj ET Q q 0 0 0 rg BT 241.31 125.25 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 284.18 125.25 Td (or) Tj ET Q q 0 0 0 rg BT 292.33 125.25 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 339.66 125.25 Td (in ) Tj ET Q q 0 0 0 rg BT 349.23 125.25 Td (the ) Tj ET Q q 0 0 0 rg BT 363.24 125.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 382.81 125.25 Td (to ) Tj ET Q q 0 0 0 rg BT 392.38 125.25 Td (a ) Tj ET Q q 0 0 0 rg BT 398.61 125.25 Td (lesser ) Tj ET Q q 0 0 0 rg BT 423.17 125.25 Td (extent. ) Tj ET Q q 0 0 0 rg BT 451.77 125.25 Td (The ) Tj ET Q q 0 0 0 rg BT 469.10 125.25 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 507.01 125.25 Td (programs ) Tj ET Q q 0 0 0 rg BT 546.57 125.25 Td (include ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.25 Td (several ) Tj ET Q q 0 0 0 rg BT 66.92 113.25 Td (dif) Tj ET Q q 0 0 0 rg BT 77.85 113.25 Td (ferent ) Tj ET Q q 0 0 0 rg BT 103.77 113.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 134.70 113.25 Td (schemes ) Tj ET Q q 0 0 0 rg BT 171.18 113.25 Td (such ) Tj ET Q q 0 0 0 rg BT 192.11 113.25 Td (as ) Tj ET Q q 0 0 0 rg BT 203.04 113.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 221.76 113.25 Td (caps, ) Tj ET Q q 0 0 0 rg BT 244.63 113.25 Td (volume ) Tj ET Q q 0 0 0 rg BT 277.23 113.25 Td (discounts, ) Tj ET Q q 0 0 0 rg BT 320.11 113.25 Td (outcome-based ) Tj ET Q q 0 0 0 rg BT 383.25 113.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 414.18 113.25 Td (schemes ) Tj ET Q q 0 0 0 rg BT 450.66 113.25 Td (and ) Tj ET Q q 0 0 0 rg BT 467.70 113.25 Td (pricing ) Tj ET Q q 0 0 0 rg BT 498.63 113.25 Td (claw-backs ) Tj ET Q q 0 0 0 rg BT 546.21 113.25 Td (that ) Tj ET Q q 0 0 0 rg BT 563.81 113.25 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.25 Td (based ) Tj ET Q q 0 0 0 rg BT 61.47 101.25 Td (on ) Tj ET Q q 0 0 0 rg BT 74.17 101.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 96.30 101.25 Td (of ) Tj ET Q q 0 0 0 rg BT 107.33 101.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 150.58 101.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 196.05 101.25 Td (or ) Tj ET Q q 0 0 0 rg BT 207.08 101.25 Td (an ) Tj ET Q q 0 0 0 rg BT 219.21 101.25 Td (aggregation ) Tj ET Q q 0 0 0 rg BT 269.12 101.25 Td (of ) Tj ET Q q 0 0 0 rg BT 280.15 101.25 Td (all ) Tj ET Q q 0 0 0 rg BT 292.84 101.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 338.30 101.25 Td (participating ) Tj ET Q q 0 0 0 rg BT 391.54 101.25 Td (in ) Tj ET Q q 0 0 0 rg BT 402.02 101.25 Td (a ) Tj ET Q q 0 0 0 rg BT 409.15 101.25 Td (specific ) Tj ET Q q 0 0 0 rg BT 442.95 101.25 Td (market. ) Tj ET Q q 0 0 0 rg BT 475.71 101.25 Td (The ) Tj ET Q q 0 0 0 rg BT 493.96 101.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 534.98 101.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 567.67 101.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 89.25 Td (unpaid ) Tj ET Q q 0 0 0 rg BT 65.72 89.25 Td (or ) Tj ET Q q 0 0 0 rg BT 76.55 89.25 Td (unbilled ) Tj ET Q q 0 0 0 rg BT 111.82 89.25 Td (rebates ) Tj ET Q q 0 0 0 rg BT 142.64 89.25 Td (and ) Tj ET Q q 0 0 0 rg BT 159.57 89.25 Td (discounts ) Tj ET Q q 0 0 0 rg BT 199.85 89.25 Td (is ) Tj ET Q q 0 0 0 rg BT 209.02 89.25 Td (presented ) Tj ET Q q 0 0 0 rg BT 249.84 89.25 Td (as ) Tj ET Q q 0 0 0 rg BT 260.67 89.25 Td (a ) Tj ET Q q 0 0 0 rg BT 267.61 89.25 Td (liability) Tj ET Q q 0 0 0 rg BT 298.07 89.25 Td (.) Tj ET Q endstream endobj 97 0 obj <> endobj 98 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (48) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 78.95 749.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 109.69 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 124.31 749.10 Td (established ) Tj ET Q q 0 0 0 rg BT 171.71 749.10 Td (products ) Tj ET Q q 0 0 0 rg BT 209.11 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 224.28 749.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 272.23 749.10 Td (after ) Tj ET Q q 0 0 0 rg BT 293.50 749.10 Td (considering ) Tj ET Q q 0 0 0 rg BT 343.12 749.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 383.30 749.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 429.56 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 446.97 749.10 Td (other ) Tj ET Q q 0 0 0 rg BT 470.48 749.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 500.65 749.10 Td (including ) Tj ET Q q 0 0 0 rg BT 541.39 749.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 567.67 749.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 76.05 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 85.56 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 99.51 737.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 147.35 737.10 Td (channel, ) Tj ET Q q 0 0 0 rg BT 182.67 737.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 222.72 737.10 Td (shelf ) Tj ET Q q 0 0 0 rg BT 243.89 737.10 Td (life, ) Tj ET Q q 0 0 0 rg BT 261.44 737.10 Td (product ) Tj ET Q q 0 0 0 rg BT 293.71 737.10 Td (recalls, ) Tj ET Q q 0 0 0 rg BT 324.04 737.10 Td (product ) Tj ET Q q 0 0 0 rg BT 356.31 737.10 Td (discontinuances, ) Tj ET Q q 0 0 0 rg BT 424.41 737.10 Td (price ) Tj ET Q q 0 0 0 rg BT 446.13 737.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 480.06 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 490.12 737.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 539.06 737.10 Td (products, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (introductions ) Tj ET Q q 0 0 0 rg BT 90.39 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 100.34 725.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 131.38 725.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 169.93 725.10 Td (introductions ) Tj ET Q q 0 0 0 rg BT 224.32 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 234.27 725.10 Td (competitive ) Tj ET Q q 0 0 0 rg BT 283.09 725.10 Td (new ) Tj ET Q q 0 0 0 rg BT 301.37 725.10 Td (products ) Tj ET Q q 0 0 0 rg BT 337.42 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 353.48 725.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 377.86 725.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 411.13 725.10 Td (following ) Tj ET Q q 0 0 0 rg BT 451.63 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 465.47 725.10 Td (LOE. ) Tj ET Q q 0 0 0 rg BT 488.91 725.10 Td (The ) Tj ET Q q 0 0 0 rg BT 506.07 725.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 546.01 725.10 Td (amount ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 713.10 Td (product ) Tj ET Q q 0 0 0 rg BT 83.21 713.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 113.48 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 122.65 713.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 163.46 713.10 Td (as ) Tj ET Q q 0 0 0 rg BT 174.29 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 181.23 713.10 Td (liability) Tj ET Q q 0 0 0 rg BT 211.69 713.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 78.36 689.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 108.50 689.10 Td (for ) Tj ET Q q 0 0 0 rg BT 122.54 689.10 Td (new ) Tj ET Q q 0 0 0 rg BT 141.57 689.10 Td (products ) Tj ET Q q 0 0 0 rg BT 178.38 689.10 Td (are ) Tj ET Q q 0 0 0 rg BT 192.96 689.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 240.31 689.10 Td (after ) Tj ET Q q 0 0 0 rg BT 261.00 689.10 Td (considering ) Tj ET Q q 0 0 0 rg BT 310.02 689.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 349.61 689.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 371.42 689.10 Td (return ) Tj ET Q q 0 0 0 rg BT 397.67 689.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 443.34 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 454.04 689.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 484.19 689.10 Td (products, ) Tj ET Q q 0 0 0 rg BT 523.50 689.10 Td (such ) Tj ET Q q 0 0 0 rg BT 544.20 689.10 Td (as ) Tj ET Q q 0 0 0 rg BT 554.90 689.10 Td (those ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (within ) Tj ET Q q 0 0 0 rg BT 64.16 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 78.98 677.10 Td (same ) Tj ET Q q 0 0 0 rg BT 102.14 677.10 Td (product ) Tj ET Q q 0 0 0 rg BT 135.29 677.10 Td (line, ) Tj ET Q q 0 0 0 rg BT 155.39 677.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 185.77 677.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 232.79 677.10 Td (area ) Tj ET Q q 0 0 0 rg BT 252.04 677.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 280.19 677.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 310.57 677.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 359.29 677.10 Td (model. ) Tj ET Q q 0 0 0 rg BT 389.20 677.10 Td (W) Tj ET Q q 0 0 0 rg BT 397.84 677.10 Td (e ) Tj ET Q q 0 0 0 rg BT 404.88 677.10 Td (defer ) Tj ET Q q 0 0 0 rg BT 428.02 677.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 476.17 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 487.11 677.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 521.36 677.10 Td (until ) Tj ET Q q 0 0 0 rg BT 542.30 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 557.12 677.10 Td (right ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 47.37 665.10 Td (return ) Tj ET Q q 0 0 0 rg BT 74.28 665.10 Td (expires, ) Tj ET Q q 0 0 0 rg BT 108.70 665.10 Td (suf) Tj ET Q q 0 0 0 rg BT 120.74 665.10 Td (ficient ) Tj ET Q q 0 0 0 rg BT 149.32 665.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 189.57 665.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 235.91 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 246.73 665.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 283.09 665.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 305.56 665.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 336.37 665.10 Td (is ) Tj ET Q q 0 0 0 rg BT 346.08 665.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 390.21 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 401.03 665.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 432.40 665.10 Td (circumstances, ) Tj ET Q q 0 0 0 rg BT 494.58 665.10 Td (or ) Tj ET Q q 0 0 0 rg BT 505.95 665.10 Td (when ) Tj ET Q q 0 0 0 rg BT 530.64 665.10 Td (insuf) Tj ET Q q 0 0 0 rg BT 550.46 665.10 Td (ficient ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 76.01 653.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 122.11 653.10 Td (with ) Tj ET Q q 0 0 0 rg BT 142.69 653.10 Td (products ) Tj ET Q q 0 0 0 rg BT 179.93 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 190.51 653.10 Td (a ) Tj ET Q q 0 0 0 rg BT 197.75 653.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 228.32 653.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 275.54 653.10 Td (area, ) Tj ET Q q 0 0 0 rg BT 297.49 653.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 346.40 653.10 Td (method ) Tj ET Q q 0 0 0 rg BT 379.20 653.10 Td (or ) Tj ET Q q 0 0 0 rg BT 390.33 653.10 Td (other ) Tj ET Q q 0 0 0 rg BT 413.67 653.10 Td (characteristic ) Tj ET Q q 0 0 0 rg BT 469.77 653.10 Td (is ) Tj ET Q q 0 0 0 rg BT 479.24 653.10 Td (available. ) Tj ET Q q 0 0 0 rg BT 520.43 653.10 Td (This ) Tj ET Q q 0 0 0 rg BT 541.01 653.10 Td (typically ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (occurs ) Tj ET Q q 0 0 0 rg BT 64.69 641.10 Td (when ) Tj ET Q q 0 0 0 rg BT 88.94 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 103.75 641.10 Td (new ) Tj ET Q q 0 0 0 rg BT 123.00 641.10 Td (product ) Tj ET Q q 0 0 0 rg BT 156.14 641.10 Td (is ) Tj ET Q q 0 0 0 rg BT 165.40 641.10 Td (not ) Tj ET Q q 0 0 0 rg BT 180.77 641.10 Td (an ) Tj ET Q q 0 0 0 rg BT 192.80 641.10 Td (extension ) Tj ET Q q 0 0 0 rg BT 233.72 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 244.64 641.10 Td (an ) Tj ET Q q 0 0 0 rg BT 256.67 641.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 290.93 641.10 Td (line ) Tj ET Q q 0 0 0 rg BT 308.52 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 319.44 641.10 Td (product ) Tj ET Q q 0 0 0 rg BT 352.58 641.10 Td (or ) Tj ET Q q 0 0 0 rg BT 363.50 641.10 Td (when ) Tj ET Q q 0 0 0 rg BT 387.75 641.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 427.55 641.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 473.45 641.10 Td (with ) Tj ET Q q 0 0 0 rg BT 493.82 641.10 Td (products ) Tj ET Q q 0 0 0 rg BT 530.85 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 541.22 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 548.25 641.10 Td (similar ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 83.35 629.10 Td (category ) Tj ET Q q 0 0 0 rg BT 120.70 629.10 Td (is ) Tj ET Q q 0 0 0 rg BT 130.29 629.10 Td (lacking. ) Tj ET Q q 0 0 0 rg BT 165.16 629.10 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 208.07 629.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 234.33 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 245.58 629.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 286.83 629.10 Td (in ) Tj ET Q q 0 0 0 rg BT 297.54 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 312.68 629.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 361.73 629.10 Td (channel ) Tj ET Q q 0 0 0 rg BT 395.75 629.10 Td (and ) Tj ET Q q 0 0 0 rg BT 413.11 629.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 453.24 629.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 487.82 629.10 Td (are ) Tj ET Q q 0 0 0 rg BT 502.96 629.10 Td (also ) Tj ET Q q 0 0 0 rg BT 521.99 629.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 568.24 629.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (estimating ) Tj ET Q q 0 0 0 rg BT 80.16 617.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 102.10 617.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 132.37 617.10 Td (for ) Tj ET Q q 0 0 0 rg BT 146.53 617.10 Td (new ) Tj ET Q q 0 0 0 rg BT 165.69 617.10 Td (products.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 591.7669921875 m 200.521484375 591.7669921875 l s q 0 0 0 rg BT 36.00 593.10 Td (Use of information fr) Tj ET Q q 0 0 0 rg BT 120.36 593.10 Td (om external sour) Tj ET Q q 0 0 0 rg BT 187.75 593.10 Td (ces) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (Information ) Tj ET Q q 0 0 0 rg BT 86.48 569.10 Td (from ) Tj ET Q q 0 0 0 rg BT 108.63 569.10 Td (external ) Tj ET Q q 0 0 0 rg BT 143.55 569.10 Td (sources ) Tj ET Q q 0 0 0 rg BT 176.26 569.10 Td (is ) Tj ET Q q 0 0 0 rg BT 185.65 569.10 Td (used ) Tj ET Q q 0 0 0 rg BT 206.69 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 217.19 569.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 253.22 569.10 Td (GTN ) Tj ET Q q 0 0 0 rg BT 276.49 569.10 Td (adjustments. ) Tj ET Q q 0 0 0 rg BT 329.48 569.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 347.75 569.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 383.79 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.83 569.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 435.87 569.10 Td (at ) Tj ET Q q 0 0 0 rg BT 445.81 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 460.74 569.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 510.66 569.10 Td (are ) Tj ET Q q 0 0 0 rg BT 525.59 569.10 Td (based ) Tj ET Q q 0 0 0 rg BT 551.07 569.10 Td (on ) Tj ET Q q 0 0 0 rg BT 563.79 569.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 76.27 557.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 127.10 557.10 Td (demand-based ) Tj ET Q q 0 0 0 rg BT 187.92 557.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 210.42 557.10 Td (for ) Tj ET Q q 0 0 0 rg BT 225.15 557.10 Td (our ) Tj ET Q q 0 0 0 rg BT 241.55 557.10 Td (products ) Tj ET Q q 0 0 0 rg BT 279.05 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 296.56 557.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 336.83 557.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 378.23 557.10 Td (experience, ) Tj ET Q q 0 0 0 rg BT 427.09 557.10 Td (as ) Tj ET Q q 0 0 0 rg BT 438.49 557.10 Td (well ) Tj ET Q q 0 0 0 rg BT 458.77 557.10 Td (as ) Tj ET Q q 0 0 0 rg BT 470.17 557.10 Td (our ) Tj ET Q q 0 0 0 rg BT 486.57 557.10 Td (analysis ) Tj ET Q q 0 0 0 rg BT 521.85 557.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.25 557.10 Td (third-party ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (information, ) Tj ET Q q 0 0 0 rg BT 88.84 545.10 Td (including ) Tj ET Q q 0 0 0 rg BT 129.75 545.10 Td (written ) Tj ET Q q 0 0 0 rg BT 161.20 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 178.77 545.10 Td (oral ) Tj ET Q q 0 0 0 rg BT 197.45 545.10 Td (information ) Tj ET Q q 0 0 0 rg BT 247.79 545.10 Td (obtained ) Tj ET Q q 0 0 0 rg BT 285.35 545.10 Td (from ) Tj ET Q q 0 0 0 rg BT 307.92 545.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 338.25 545.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 388.59 545.10 Td (with ) Tj ET Q q 0 0 0 rg BT 409.50 545.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 440.94 545.10 Td (to ) Tj ET Q q 0 0 0 rg BT 451.85 545.10 Td (their ) Tj ET Q q 0 0 0 rg BT 473.30 545.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 514.76 545.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 541.21 545.10 Td (and ) Tj ET Q q 0 0 0 rg BT 558.78 545.10 Td (sell-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.10 Td (through ) Tj ET Q q 0 0 0 rg BT 70.92 533.10 Td (to ) Tj ET Q q 0 0 0 rg BT 82.51 533.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 126.87 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 145.12 533.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 191.70 533.10 Td (market ) Tj ET Q q 0 0 0 rg BT 223.28 533.10 Td (research ) Tj ET Q q 0 0 0 rg BT 260.40 533.10 Td (data, ) Tj ET Q q 0 0 0 rg BT 283.36 533.10 Td (and ) Tj ET Q q 0 0 0 rg BT 301.62 533.10 Td (our ) Tj ET Q q 0 0 0 rg BT 318.76 533.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 353.11 533.10 Td (information. ) Tj ET Q q 0 0 0 rg BT 406.36 533.10 Td (The ) Tj ET Q q 0 0 0 rg BT 425.72 533.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 467.86 533.10 Td (information ) Tj ET Q q 0 0 0 rg BT 518.89 533.10 Td (received ) Tj ET Q q 0 0 0 rg BT 556.56 533.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 85.20 521.10 Td (is ) Tj ET Q q 0 0 0 rg BT 93.87 521.10 Td (a ) Tj ET Q q 0 0 0 rg BT 100.30 521.10 Td (product ) Tj ET Q q 0 0 0 rg BT 132.84 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 143.17 521.10 Td (their ) Tj ET Q q 0 0 0 rg BT 163.49 521.10 Td (recordkeeping ) Tj ET Q q 0 0 0 rg BT 222.67 521.10 Td (process ) Tj ET Q q 0 0 0 rg BT 254.66 521.10 Td (and ) Tj ET Q q 0 0 0 rg BT 271.09 521.10 Td (excludes ) Tj ET Q q 0 0 0 rg BT 308.07 521.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 348.39 521.10 Td (held ) Tj ET Q q 0 0 0 rg BT 367.60 521.10 Td (by ) Tj ET Q q 0 0 0 rg BT 379.60 521.10 Td (intermediaries ) Tj ET Q q 0 0 0 rg BT 438.79 521.10 Td (to ) Tj ET Q q 0 0 0 rg BT 448.56 521.10 Td (whom ) Tj ET Q q 0 0 0 rg BT 475.56 521.10 Td (they ) Tj ET Q q 0 0 0 rg BT 494.77 521.10 Td (sell, ) Tj ET Q q 0 0 0 rg BT 513.15 521.10 Td (such ) Tj ET Q q 0 0 0 rg BT 533.47 521.10 Td (as ) Tj ET Q q 0 0 0 rg BT 543.80 521.10 Td (retailers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 509.10 Td (hospitals.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 485.10 Td (e ) Tj ET Q q 0 0 0 rg BT 50.63 485.10 Td (have ) Tj ET Q q 0 0 0 rg BT 71.06 485.10 Td (also ) Tj ET Q q 0 0 0 rg BT 88.72 485.10 Td (continued ) Tj ET Q q 0 0 0 rg BT 129.71 485.10 Td (the ) Tj ET Q q 0 0 0 rg BT 143.48 485.10 Td (practice ) Tj ET Q q 0 0 0 rg BT 176.67 485.10 Td (of ) Tj ET Q q 0 0 0 rg BT 186.55 485.10 Td (combining ) Tj ET Q q 0 0 0 rg BT 230.88 485.10 Td (retail ) Tj ET Q q 0 0 0 rg BT 252.97 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 268.96 485.10 Td (mail ) Tj ET Q q 0 0 0 rg BT 288.29 485.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 337.61 485.10 Td (volume ) Tj ET Q q 0 0 0 rg BT 369.15 485.10 Td (on ) Tj ET Q q 0 0 0 rg BT 380.71 485.10 Td (a ) Tj ET Q q 0 0 0 rg BT 386.70 485.10 Td (retail-equivalent ) Tj ET Q q 0 0 0 rg BT 453.77 485.10 Td (basis. ) Tj ET Q q 0 0 0 rg BT 477.71 485.10 Td (W) Tj ET Q q 0 0 0 rg BT 486.35 485.10 Td (e ) Tj ET Q q 0 0 0 rg BT 492.34 485.10 Td (use ) Tj ET Q q 0 0 0 rg BT 507.23 485.10 Td (this ) Tj ET Q q 0 0 0 rg BT 523.23 485.10 Td (methodology ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (for ) Tj ET Q q 0 0 0 rg BT 49.82 473.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 82.53 473.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 116.35 473.10 Td (forecasts. ) Tj ET Q q 0 0 0 rg BT 156.39 473.10 Td (W) Tj ET Q q 0 0 0 rg BT 165.03 473.10 Td (e ) Tj ET Q q 0 0 0 rg BT 171.63 473.10 Td (also ) Tj ET Q q 0 0 0 rg BT 189.90 473.10 Td (use ) Tj ET Q q 0 0 0 rg BT 205.39 473.10 Td (information ) Tj ET Q q 0 0 0 rg BT 254.77 473.10 Td (from ) Tj ET Q q 0 0 0 rg BT 276.37 473.10 Td (external ) Tj ET Q q 0 0 0 rg BT 310.74 473.10 Td (sources ) Tj ET Q q 0 0 0 rg BT 342.89 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 352.83 473.10 Td (identify ) Tj ET Q q 0 0 0 rg BT 386.10 473.10 Td (prescription ) Tj ET Q q 0 0 0 rg BT 436.02 473.10 Td (trends, ) Tj ET Q q 0 0 0 rg BT 465.13 473.10 Td (patient ) Tj ET Q q 0 0 0 rg BT 494.50 473.10 Td (demand ) Tj ET Q q 0 0 0 rg BT 528.32 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 544.92 473.10 Td (average ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 65.64 461.10 Td (prices. ) Tj ET Q q 0 0 0 rg BT 94.98 461.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 113.51 461.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 153.69 461.10 Td (are ) Tj ET Q q 0 0 0 rg BT 168.87 461.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 200.17 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 210.91 461.10 Td (inherent ) Tj ET Q q 0 0 0 rg BT 246.65 461.10 Td (limitations ) Tj ET Q q 0 0 0 rg BT 292.40 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 303.70 461.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 343.88 461.10 Td (that ) Tj ET Q q 0 0 0 rg BT 361.85 461.10 Td (rely ) Tj ET Q q 0 0 0 rg BT 380.37 461.10 Td (on ) Tj ET Q q 0 0 0 rg BT 393.34 461.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 439.07 461.10 Td (information, ) Tj ET Q q 0 0 0 rg BT 491.76 461.10 Td (as ) Tj ET Q q 0 0 0 rg BT 503.06 461.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 533.23 461.10 Td (third-party ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (information ) Tj ET Q q 0 0 0 rg BT 86.54 449.10 Td (was ) Tj ET Q q 0 0 0 rg BT 105.42 449.10 Td (itself ) Tj ET Q q 0 0 0 rg BT 128.74 449.10 Td (in ) Tj ET Q q 0 0 0 rg BT 139.85 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 155.39 449.10 Td (form ) Tj ET Q q 0 0 0 rg BT 178.16 449.10 Td (of ) Tj ET Q q 0 0 0 rg BT 189.82 449.10 Td (estimates, ) Tj ET Q q 0 0 0 rg BT 232.86 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 250.62 449.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 279.48 449.10 Td (other ) Tj ET Q q 0 0 0 rg BT 303.36 449.10 Td (limitations ) Tj ET Q q 0 0 0 rg BT 349.46 449.10 Td (including ) Tj ET Q q 0 0 0 rg BT 390.56 449.10 Td (lags ) Tj ET Q q 0 0 0 rg BT 410.00 449.10 Td (between ) Tj ET Q q 0 0 0 rg BT 446.64 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 462.19 449.10 Td (date ) Tj ET Q q 0 0 0 rg BT 482.17 449.10 Td (as ) Tj ET Q q 0 0 0 rg BT 493.83 449.10 Td (of ) Tj ET Q q 0 0 0 rg BT 505.48 449.10 Td (which ) Tj ET Q q 0 0 0 rg BT 533.25 449.10 Td (third-party ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (information ) Tj ET Q q 0 0 0 rg BT 85.71 437.10 Td (is ) Tj ET Q q 0 0 0 rg BT 94.88 437.10 Td (generated ) Tj ET Q q 0 0 0 rg BT 136.24 437.10 Td (and ) Tj ET Q q 0 0 0 rg BT 153.18 437.10 Td (the ) Tj ET Q q 0 0 0 rg BT 167.90 437.10 Td (date ) Tj ET Q q 0 0 0 rg BT 187.05 437.10 Td (on ) Tj ET Q q 0 0 0 rg BT 199.55 437.10 Td (which ) Tj ET Q q 0 0 0 rg BT 226.49 437.10 Td (we ) Tj ET Q q 0 0 0 rg BT 240.65 437.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 272.02 437.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 317.28 437.10 Td (information.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (Retirement ) Tj ET Q q 0 0 0 rg BT 84.05 413.10 Td (Benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 84.71 389.10 Td (for ) Tj ET Q q 0 0 0 rg BT 98.43 389.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 131.60 389.10 Td (and ) Tj ET Q q 0 0 0 rg BT 148.09 389.10 Td (postretirement ) Tj ET Q q 0 0 0 rg BT 207.91 389.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 237.73 389.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 260.90 389.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 295.17 389.10 Td (actuarial ) Tj ET Q q 0 0 0 rg BT 331.64 389.10 Td (valuations ) Tj ET Q q 0 0 0 rg BT 374.80 389.10 Td (based ) Tj ET Q q 0 0 0 rg BT 399.63 389.10 Td (on ) Tj ET Q q 0 0 0 rg BT 411.69 389.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 455.96 389.10 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 507.46 389.10 Td (for ) Tj ET Q q 0 0 0 rg BT 521.18 389.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 557.13 389.10 Td (rates ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.11 377.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 91.31 377.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 133.41 377.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 154.96 377.10 Td (of ) Tj ET Q q 0 0 0 rg BT 165.95 377.10 Td (return ) Tj ET Q q 0 0 0 rg BT 192.50 377.10 Td (on ) Tj ET Q q 0 0 0 rg BT 205.17 377.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 225.05 377.10 Td (assets. ) Tj ET Q q 0 0 0 rg BT 253.55 377.10 Td (In ) Tj ET Q q 0 0 0 rg BT 264.55 377.10 Td (consultation ) Tj ET Q q 0 0 0 rg BT 316.10 377.10 Td (with ) Tj ET Q q 0 0 0 rg BT 336.55 377.10 Td (our ) Tj ET Q q 0 0 0 rg BT 352.55 377.10 Td (actuaries, ) Tj ET Q q 0 0 0 rg BT 393.25 377.10 Td (these ) Tj ET Q q 0 0 0 rg BT 416.46 377.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 461.34 377.10 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 513.46 377.10 Td (and ) Tj ET Q q 0 0 0 rg BT 530.57 377.10 Td (others ) Tj ET Q q 0 0 0 rg BT 557.67 377.10 Td (such ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (as ) Tj ET Q q 0 0 0 rg BT 47.10 365.10 Td (salary ) Tj ET Q q 0 0 0 rg BT 73.74 365.10 Td (growth, ) Tj ET Q q 0 0 0 rg BT 107.34 365.10 Td (retirement, ) Tj ET Q q 0 0 0 rg BT 153.69 365.10 Td (turnover) Tj ET Q q 0 0 0 rg BT 187.17 365.10 Td (, ) Tj ET Q q 0 0 0 rg BT 192.43 365.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 236.28 365.10 Td (trends ) Tj ET Q q 0 0 0 rg BT 263.48 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 280.69 365.10 Td (mortality ) Tj ET Q q 0 0 0 rg BT 320.11 365.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 341.76 365.10 Td (are ) Tj ET Q q 0 0 0 rg BT 356.73 365.10 Td (evaluated ) Tj ET Q q 0 0 0 rg BT 397.81 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 415.01 365.10 Td (selected ) Tj ET Q q 0 0 0 rg BT 449.98 365.10 Td (based ) Tj ET Q q 0 0 0 rg BT 475.51 365.10 Td (on ) Tj ET Q q 0 0 0 rg BT 488.28 365.10 Td (expectations ) Tj ET Q q 0 0 0 rg BT 541.03 365.10 Td (or ) Tj ET Q q 0 0 0 rg BT 552.12 365.10 Td (actual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 80.95 353.10 Td (during ) Tj ET Q q 0 0 0 rg BT 108.70 353.10 Td (each ) Tj ET Q q 0 0 0 rg BT 128.67 353.10 Td (remeasurement ) Tj ET Q q 0 0 0 rg BT 191.39 353.10 Td (date. ) Tj ET Q q 0 0 0 rg BT 212.19 353.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 245.51 353.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 279.36 353.10 Td (could ) Tj ET Q q 0 0 0 rg BT 303.23 353.10 Td (vary ) Tj ET Q q 0 0 0 rg BT 322.64 353.10 Td (within ) Tj ET Q q 0 0 0 rg BT 349.85 353.10 Td (a ) Tj ET Q q 0 0 0 rg BT 355.93 353.10 Td (range ) Tj ET Q q 0 0 0 rg BT 379.79 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 389.76 353.10 Td (outcomes ) Tj ET Q q 0 0 0 rg BT 429.74 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 445.82 353.10 Td (have ) Tj ET Q q 0 0 0 rg BT 466.35 353.10 Td (a ) Tj ET Q q 0 0 0 rg BT 472.43 353.10 Td (material ) Tj ET Q q 0 0 0 rg BT 506.84 353.10 Td (ef) Tj ET Q q 0 0 0 rg BT 514.42 353.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 531.06 353.10 Td (on ) Tj ET Q q 0 0 0 rg BT 542.70 353.10 Td (reported ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (earnings, ) Tj ET Q q 0 0 0 rg BT 74.53 341.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 113.88 341.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 143.79 341.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 190.39 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 206.97 341.10 Td (future ) Tj ET Q q 0 0 0 rg BT 233.00 341.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 252.92 341.10 Td (funding. ) Tj ET Q q 0 0 0 rg BT 288.20 341.10 Td (Actual ) Tj ET Q q 0 0 0 rg BT 317.01 341.10 Td (results ) Tj ET Q q 0 0 0 rg BT 345.27 341.10 Td (in ) Tj ET Q q 0 0 0 rg BT 355.19 341.10 Td (any ) Tj ET Q q 0 0 0 rg BT 371.78 341.10 Td (given ) Tj ET Q q 0 0 0 rg BT 396.15 341.10 Td (year ) Tj ET Q q 0 0 0 rg BT 415.51 341.10 Td (may ) Tj ET Q q 0 0 0 rg BT 434.87 341.10 Td (dif) Tj ET Q q 0 0 0 rg BT 445.80 341.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 459.05 341.10 Td (from ) Tj ET Q q 0 0 0 rg BT 480.64 341.10 Td (those ) Tj ET Q q 0 0 0 rg BT 503.90 341.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 544.37 341.10 Td (because ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.83 329.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 88.20 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 105.14 329.10 Td (other ) Tj ET Q q 0 0 0 rg BT 128.19 329.10 Td (factors.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.16 305.10 Td (yield ) Tj ET Q q 0 0 0 rg BT 76.77 305.10 Td (on ) Tj ET Q q 0 0 0 rg BT 89.39 305.10 Td (high ) Tj ET Q q 0 0 0 rg BT 109.78 305.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 140.17 305.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 180.54 305.10 Td (bonds ) Tj ET Q q 0 0 0 rg BT 207.04 305.10 Td (that ) Tj ET Q q 0 0 0 rg BT 224.65 305.10 Td (coincides ) Tj ET Q q 0 0 0 rg BT 265.03 305.10 Td (with ) Tj ET Q q 0 0 0 rg BT 285.42 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 300.26 305.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 320.64 305.10 Td (flows ) Tj ET Q q 0 0 0 rg BT 345.48 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 356.42 305.10 Td (the ) Tj ET Q q 0 0 0 rg BT 371.25 305.10 Td (plans’) Tj ET Q q 0 0 0 rg BT 394.95 305.10 Td ( ) Tj ET Q q 0 0 0 rg BT 397.56 305.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 438.50 305.10 Td (payouts ) Tj ET Q q 0 0 0 rg BT 472.22 305.10 Td (is ) Tj ET Q q 0 0 0 rg BT 481.51 305.10 Td (used ) Tj ET Q q 0 0 0 rg BT 502.45 305.10 Td (in ) Tj ET Q q 0 0 0 rg BT 512.84 305.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 563.78 305.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 72.18 293.10 Td (rate. ) Tj ET Q q 0 0 0 rg BT 91.80 293.10 Td (The ) Tj ET Q q 0 0 0 rg BT 109.65 293.10 Td (Citi ) Tj ET Q q 0 0 0 rg BT 126.95 293.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 160.91 293.10 Td (Discount ) Tj ET Q q 0 0 0 rg BT 199.32 293.10 Td (curve ) Tj ET Q q 0 0 0 rg BT 223.82 293.10 Td (is ) Tj ET Q q 0 0 0 rg BT 232.79 293.10 Td (used ) Tj ET Q q 0 0 0 rg BT 253.42 293.10 Td (for ) Tj ET Q q 0 0 0 rg BT 267.38 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 281.89 293.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 301.97 293.10 Td (plans. ) Tj ET Q q 0 0 0 rg BT 327.71 293.10 Td (The ) Tj ET Q q 0 0 0 rg BT 345.56 293.10 Td (present ) Tj ET Q q 0 0 0 rg BT 376.73 293.10 Td (value ) Tj ET Q q 0 0 0 rg BT 400.68 293.10 Td (of ) Tj ET Q q 0 0 0 rg BT 411.31 293.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 441.37 293.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 488.11 293.10 Td (at ) Tj ET Q q 0 0 0 rg BT 497.63 293.10 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.01 293.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (for ) Tj ET Q q 0 0 0 rg BT 49.91 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 64.38 281.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 84.42 281.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 117.78 281.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 141.14 281.10 Td (was ) Tj ET Q q 0 0 0 rg BT 158.95 281.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 206.18 281.10 Td (using ) Tj ET Q q 0 0 0 rg BT 230.11 281.10 Td (a ) Tj ET Q q 0 0 0 rg BT 236.80 281.10 Td (3.5% ) Tj ET Q q 0 0 0 rg BT 259.88 281.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 296.02 281.10 Td (rate. ) Tj ET Q q 0 0 0 rg BT 315.76 281.10 Td (If ) Tj ET Q q 0 0 0 rg BT 324.67 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 339.14 281.10 Td (assumed ) Tj ET Q q 0 0 0 rg BT 375.84 281.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 411.98 281.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 429.22 281.10 Td (used ) Tj ET Q q 0 0 0 rg BT 449.80 281.10 Td (in ) Tj ET Q q 0 0 0 rg BT 459.83 281.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 510.40 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 524.87 281.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 544.91 281.10 Td (pension ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (plans’) Tj ET Q q 0 0 0 rg BT 59.70 269.10 Td ( ) Tj ET Q q 0 0 0 rg BT 61.34 269.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 100.18 269.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 129.59 269.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 171.78 269.10 Td (at ) Tj ET Q q 0 0 0 rg BT 180.64 269.10 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 238.37 269.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 258.37 269.10 Td ( ) Tj ET Q q 0 0 0 rg BT 260.01 269.10 Td (was ) Tj ET Q q 0 0 0 rg BT 277.20 269.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 310.49 269.10 Td (by ) Tj ET Q q 0 0 0 rg BT 322.13 269.10 Td (an ) Tj ET Q q 0 0 0 rg BT 333.21 269.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 374.85 269.10 Td (1%, ) Tj ET Q q 0 0 0 rg BT 392.32 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 406.18 269.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 445.02 269.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 474.43 269.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 516.62 269.10 Td (would ) Tj ET Q q 0 0 0 rg BT 543.26 269.10 Td (increase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (by ) Tj ET Q q 0 0 0 rg BT 48.50 257.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 108.76 257.10 Td ($950 ) Tj ET Q q 0 0 0 rg BT 131.26 257.10 Td (million.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.53 233.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 91.04 233.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 132.46 233.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 149.42 233.10 Td (of ) Tj ET Q q 0 0 0 rg BT 159.74 233.10 Td (return ) Tj ET Q q 0 0 0 rg BT 185.59 233.10 Td (on ) Tj ET Q q 0 0 0 rg BT 197.58 233.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 216.77 233.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 242.08 233.10 Td (is ) Tj ET Q q 0 0 0 rg BT 250.74 233.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 291.04 233.10 Td (considering ) Tj ET Q q 0 0 0 rg BT 339.67 233.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 377.19 233.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 406.94 233.10 Td (for ) Tj ET Q q 0 0 0 rg BT 420.58 233.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 463.11 233.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 484.53 233.10 Td (classes ) Tj ET Q q 0 0 0 rg BT 514.28 233.10 Td (with ) Tj ET Q q 0 0 0 rg BT 534.04 233.10 Td (input ) Tj ET Q q 0 0 0 rg BT 556.58 233.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.10 Td (external ) Tj ET Q q 0 0 0 rg BT 72.05 221.10 Td (advisors. ) Tj ET Q q 0 0 0 rg BT 111.44 221.10 Td (W) Tj ET Q q 0 0 0 rg BT 120.08 221.10 Td (e ) Tj ET Q q 0 0 0 rg BT 128.36 221.10 Td (also ) Tj ET Q q 0 0 0 rg BT 148.31 221.10 Td (consider ) Tj ET Q q 0 0 0 rg BT 186.03 221.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 229.31 221.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 270.36 221.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 301.98 221.10 Td (including ) Tj ET Q q 0 0 0 rg BT 343.59 221.10 Td (actual ) Tj ET Q q 0 0 0 rg BT 371.31 221.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 425.67 221.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 468.94 221.10 Td (to ) Tj ET Q q 0 0 0 rg BT 480.56 221.10 Td (benchmarks ) Tj ET Q q 0 0 0 rg BT 532.72 221.10 Td (for ) Tj ET Q q 0 0 0 rg BT 548.22 221.10 Td (similar ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (investments. ) Tj ET Q q 0 0 0 rg BT 88.42 209.10 Td (The ) Tj ET Q q 0 0 0 rg BT 106.28 209.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 126.37 209.10 Td (plans’) Tj ET Q q 0 0 0 rg BT 150.07 209.10 Td ( ) Tj ET Q q 0 0 0 rg BT 152.38 209.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 185.80 209.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 220.32 209.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 234.29 209.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 254.29 209.10 Td ( ) Tj ET Q q 0 0 0 rg BT 256.60 209.10 Td (was ) Tj ET Q q 0 0 0 rg BT 274.47 209.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 321.76 209.10 Td (using ) Tj ET Q q 0 0 0 rg BT 345.74 209.10 Td (a ) Tj ET Q q 0 0 0 rg BT 352.49 209.10 Td (7.8% ) Tj ET Q q 0 0 0 rg BT 375.64 209.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 413.48 209.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 455.23 209.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 472.52 209.10 Td (of ) Tj ET Q q 0 0 0 rg BT 483.16 209.10 Td (return ) Tj ET Q q 0 0 0 rg BT 509.35 209.10 Td (on ) Tj ET Q q 0 0 0 rg BT 521.67 209.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 541.19 209.10 Td (assets. ) Tj ET Q q 0 0 0 rg BT 569.34 209.10 Td (If ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.90 197.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 89.11 197.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 131.22 197.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 148.89 197.10 Td (of ) Tj ET Q q 0 0 0 rg BT 159.90 197.10 Td (return ) Tj ET Q q 0 0 0 rg BT 186.45 197.10 Td (on ) Tj ET Q q 0 0 0 rg BT 199.13 197.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 219.03 197.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 245.04 197.10 Td (used ) Tj ET Q q 0 0 0 rg BT 266.05 197.10 Td (in ) Tj ET Q q 0 0 0 rg BT 276.51 197.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 327.51 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 342.40 197.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 362.87 197.10 Td (plans’) Tj ET Q q 0 0 0 rg BT 386.56 197.10 Td ( ) Tj ET Q q 0 0 0 rg BT 389.24 197.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 423.03 197.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 457.92 197.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.26 197.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.26 197.10 Td ( ) Tj ET Q q 0 0 0 rg BT 494.94 197.10 Td (was ) Tj ET Q q 0 0 0 rg BT 513.17 197.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 547.49 197.10 Td (by ) Tj ET Q q 0 0 0 rg BT 560.17 197.10 Td (1%, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.10 Td (such ) Tj ET Q q 0 0 0 rg BT 56.83 185.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 91.54 185.10 Td (would ) Tj ET Q q 0 0 0 rg BT 119.04 185.10 Td (increase ) Tj ET Q q 0 0 0 rg BT 154.29 185.10 Td (by ) Tj ET Q q 0 0 0 rg BT 166.79 185.10 Td ($40 ) Tj ET Q q 0 0 0 rg BT 184.29 185.10 Td (million.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (For ) Tj ET Q q 0 0 0 rg BT 53.17 161.10 Td (a ) Tj ET Q q 0 0 0 rg BT 60.88 161.10 Td (more ) Tj ET Q q 0 0 0 rg BT 84.71 161.10 Td (detailed ) Tj ET Q q 0 0 0 rg BT 119.63 161.10 Td (discussion ) Tj ET Q q 0 0 0 rg BT 164.58 161.10 Td (on ) Tj ET Q q 0 0 0 rg BT 177.86 161.10 Td (retirement ) Tj ET Q q 0 0 0 rg BT 222.22 161.10 Td (benefits, ) Tj ET Q q 0 0 0 rg BT 259.65 161.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 281.80 161.10 Td (to ) Tj ET Q q 0 0 0 rg BT 292.85 161.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 318.89 161.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 329.67 161.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 370.16 161.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.75 161.10 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 456.75 161.10 Td (. ) Tj ET Q q 0 0 0 rg BT 462.53 161.10 Td (Pension, ) Tj ET Q q 0 0 0 rg BT 499.97 161.10 Td (Postretirement ) Tj ET Q q 0 0 0 rg BT 561.57 161.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.10 Td (Postemployment ) Tj ET Q q 0 0 0 rg BT 105.72 149.10 Td (Liabilities.”) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (Business Combinations and Divestitures) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.10 Td (Goodwill ) Tj ET Q q 0 0 0 rg BT 76.08 101.10 Td (and ) Tj ET Q q 0 0 0 rg BT 92.82 101.10 Td (other ) Tj ET Q q 0 0 0 rg BT 115.66 101.10 Td (intangible ) Tj ET Q q 0 0 0 rg BT 157.95 101.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 183.58 101.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 220.31 101.10 Td (in ) Tj ET Q q 0 0 0 rg BT 230.38 101.10 Td (business ) Tj ET Q q 0 0 0 rg BT 266.58 101.10 Td (combinations, ) Tj ET Q q 0 0 0 rg BT 325.26 101.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 363.66 101.10 Td (and ) Tj ET Q q 0 0 0 rg BT 380.40 101.10 Td (other ) Tj ET Q q 0 0 0 rg BT 403.25 101.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 453.31 101.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.04 101.10 Td ($8.1 ) Tj ET Q q 0 0 0 rg BT 494.84 101.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.95 101.10 Td ( ) Tj ET Q q 0 0 0 rg BT 523.25 101.10 Td (\(representing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 89.10 Td (24%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.33 89.10 Td ( ) Tj ET Q q 0 0 0 rg BT 56.83 89.10 Td (of ) Tj ET Q q 0 0 0 rg BT 67.66 89.10 Td (total ) Tj ET Q q 0 0 0 rg BT 87.93 89.10 Td (assets\) ) Tj ET Q q 0 0 0 rg BT 117.09 89.10 Td (at ) Tj ET Q q 0 0 0 rg BT 126.81 89.10 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 185.39 89.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.39 89.10 Td (.) Tj ET Q endstream endobj 99 0 obj <> endobj 100 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 85.25 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 99.50 749.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 149.86 749.10 Td (as ) Tj ET Q q 0 0 0 rg BT 160.79 749.10 Td (business ) Tj ET Q q 0 0 0 rg BT 197.27 749.10 Td (combinations ) Tj ET Q q 0 0 0 rg BT 253.75 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 270.78 749.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 319.48 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 328.74 749.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 381.33 749.10 Td (dif) Tj ET Q q 0 0 0 rg BT 392.25 749.10 Td (ferent ) Tj ET Q q 0 0 0 rg BT 418.16 749.10 Td (than ) Tj ET Q q 0 0 0 rg BT 437.98 749.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 460.01 749.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 510.38 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 527.41 749.10 Td (divestitures. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (For ) Tj ET Q q 0 0 0 rg BT 51.99 737.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 90.46 737.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 126.98 737.10 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 151.87 737.10 Td (is ) Tj ET Q q 0 0 0 rg BT 160.63 737.10 Td (capitalized ) Tj ET Q q 0 0 0 rg BT 206.04 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 219.80 737.10 Td (business ) Tj ET Q q 0 0 0 rg BT 255.79 737.10 Td (combinations ) Tj ET Q q 0 0 0 rg BT 311.77 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 328.30 737.10 Td (expensed ) Tj ET Q q 0 0 0 rg BT 367.61 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 381.37 737.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 402.91 737.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 452.78 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 469.32 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 483.63 737.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 499.61 737.10 Td (value ) Tj ET Q q 0 0 0 rg BT 523.36 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.79 737.10 Td (contingent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 92.44 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 109.45 725.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 147.58 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 162.35 725.10 Td (only ) Tj ET Q q 0 0 0 rg BT 182.70 725.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 229.13 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 239.48 725.10 Td (business ) Tj ET Q q 0 0 0 rg BT 275.94 725.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 328.50 725.10 Td (transactions. ) Tj ET Q q 0 0 0 rg BT 381.34 725.10 Td (Likewise, ) Tj ET Q q 0 0 0 rg BT 423.06 725.10 Td (when ) Tj ET Q q 0 0 0 rg BT 447.29 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 454.30 725.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 485.76 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 496.66 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 503.67 725.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 542.89 725.10 Td (unit ) Tj ET Q q 0 0 0 rg BT 561.02 725.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (constitutes ) Tj ET Q q 0 0 0 rg BT 81.10 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 87.86 713.10 Td (business ) Tj ET Q q 0 0 0 rg BT 124.08 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 133.07 713.10 Td (divested, ) Tj ET Q q 0 0 0 rg BT 171.22 713.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 209.10 713.10 Td (associated ) Tj ET Q q 0 0 0 rg BT 252.52 713.10 Td (with ) Tj ET Q q 0 0 0 rg BT 272.62 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 289.94 713.10 Td (business ) Tj ET Q q 0 0 0 rg BT 326.16 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 335.15 713.10 Td (included ) Tj ET Q q 0 0 0 rg BT 371.91 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 382.01 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 396.55 713.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 432.19 713.10 Td (value ) Tj ET Q q 0 0 0 rg BT 456.17 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 466.83 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 481.37 713.10 Td (business ) Tj ET Q q 0 0 0 rg BT 517.58 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 527.68 713.10 Td (determining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.09 701.10 Td (gain ) Tj ET Q q 0 0 0 rg BT 69.17 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 79.37 701.10 Td (loss. ) Tj ET Q q 0 0 0 rg BT 99.31 701.10 Td (Derecognition ) Tj ET Q q 0 0 0 rg BT 158.38 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 168.58 701.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 206.00 701.10 Td (does ) Tj ET Q q 0 0 0 rg BT 226.21 701.10 Td (not ) Tj ET Q q 0 0 0 rg BT 240.85 701.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 264.93 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 274.58 701.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 295.89 701.10 Td (dispositions. ) Tj ET Q q 0 0 0 rg BT 347.63 701.10 Td (As ) Tj ET Q q 0 0 0 rg BT 360.62 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 366.93 701.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 393.51 701.10 Td (it ) Tj ET Q q 0 0 0 rg BT 400.94 701.10 Td (is ) Tj ET Q q 0 0 0 rg BT 409.48 701.10 Td (important ) Tj ET Q q 0 0 0 rg BT 450.23 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 459.88 701.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 501.73 701.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 535.81 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 542.12 701.10 Td (business ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 46.88 689.10 Td (an ) Tj ET Q q 0 0 0 rg BT 58.87 689.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 80.85 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 91.73 689.10 Td (group ) Tj ET Q q 0 0 0 rg BT 117.61 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 128.49 689.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 154.37 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 163.59 689.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 200.56 689.10 Td (or ) Tj ET Q q 0 0 0 rg BT 211.44 689.10 Td (divested. ) Tj ET Q q 0 0 0 rg BT 249.25 689.10 Td (A) Tj ET Q q 0 0 0 rg BT 255.92 689.10 Td ( ) Tj ET Q q 0 0 0 rg BT 258.47 689.10 Td (business ) Tj ET Q q 0 0 0 rg BT 294.91 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 304.13 689.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 336.66 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 346.43 689.10 Td (ASC ) Tj ET Q q 0 0 0 rg BT 368.43 689.10 Td (805 ) Tj ET Q q 0 0 0 rg BT 385.98 689.10 Td (- ) Tj ET Q q 0 0 0 rg BT 391.86 689.10 Td (Business ) Tj ET Q q 0 0 0 rg BT 429.97 689.10 Td (Combinations ) Tj ET Q q 0 0 0 rg BT 488.63 689.10 Td (as ) Tj ET Q q 0 0 0 rg BT 499.51 689.10 Td (an ) Tj ET Q q 0 0 0 rg BT 511.50 689.10 Td (integrated ) Tj ET Q q 0 0 0 rg BT 554.03 689.10 Td (set ) Tj ET Q q 0 0 0 rg BT 567.68 689.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 63.36 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 80.72 677.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 121.95 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 139.86 677.10 Td (are ) Tj ET Q q 0 0 0 rg BT 154.98 677.10 Td (capable ) Tj ET Q q 0 0 0 rg BT 188.43 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 199.68 677.10 Td (generating ) Tj ET Q q 0 0 0 rg BT 244.79 677.10 Td (outputs ) Tj ET Q q 0 0 0 rg BT 277.16 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 295.07 677.10 Td (have ) Tj ET Q q 0 0 0 rg BT 316.86 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 331.99 677.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 360.46 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 371.15 677.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 404.61 677.10 Td (a ) Tj ET Q q 0 0 0 rg BT 411.97 677.10 Td (return ) Tj ET Q q 0 0 0 rg BT 438.76 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 449.45 677.10 Td (its ) Tj ET Q q 0 0 0 rg BT 461.82 677.10 Td (investors ) Tj ET Q q 0 0 0 rg BT 500.84 677.10 Td (or ) Tj ET Q q 0 0 0 rg BT 512.08 677.10 Td (owners. ) Tj ET Q q 0 0 0 rg BT 546.17 677.10 Td (T) Tj ET Q q 0 0 0 rg BT 551.58 677.10 Td (ypical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 63.59 665.10 Td (include ) Tj ET Q q 0 0 0 rg BT 96.16 665.10 Td (long-lived ) Tj ET Q q 0 0 0 rg BT 140.40 665.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 166.87 665.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 211.11 665.10 Td (intangible ) Tj ET Q q 0 0 0 rg BT 254.24 665.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 280.71 665.10 Td (or ) Tj ET Q q 0 0 0 rg BT 292.18 665.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 318.10 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 329.01 665.10 Td (use ) Tj ET Q q 0 0 0 rg BT 345.48 665.10 Td (long-lived ) Tj ET Q q 0 0 0 rg BT 389.72 665.10 Td (assets\), ) Tj ET Q q 0 0 0 rg BT 422.02 665.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 469.58 665.10 Td (property ) Tj ET Q q 0 0 0 rg BT 506.60 665.10 Td (and ) Tj ET Q q 0 0 0 rg BT 524.18 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 539.53 665.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 568.22 665.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (obtain ) Tj ET Q q 0 0 0 rg BT 62.83 653.10 Td (access ) Tj ET Q q 0 0 0 rg BT 90.21 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 99.82 653.10 Td (required ) Tj ET Q q 0 0 0 rg BT 134.98 653.10 Td (resources. ) Tj ET Q q 0 0 0 rg BT 176.94 653.10 Td (T) Tj ET Q q 0 0 0 rg BT 182.35 653.10 Td (ypical ) Tj ET Q q 0 0 0 rg BT 208.62 653.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 248.78 653.10 Td (include ) Tj ET Q q 0 0 0 rg BT 280.05 653.10 Td (strategic, ) Tj ET Q q 0 0 0 rg BT 318.26 653.10 Td (operational ) Tj ET Q q 0 0 0 rg BT 365.08 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 381.35 653.10 Td (resource ) Tj ET Q q 0 0 0 rg BT 417.06 653.10 Td (management ) Tj ET Q q 0 0 0 rg BT 469.98 653.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 510.14 653.10 Td (that ) Tj ET Q q 0 0 0 rg BT 526.97 653.10 Td (are ) Tj ET Q q 0 0 0 rg BT 541.02 653.10 Td (typically ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (documented ) Tj ET Q q 0 0 0 rg BT 87.37 641.10 Td (or ) Tj ET Q q 0 0 0 rg BT 98.20 641.10 Td (evident ) Tj ET Q q 0 0 0 rg BT 130.14 641.10 Td (through ) Tj ET Q q 0 0 0 rg BT 163.74 641.10 Td (an ) Tj ET Q q 0 0 0 rg BT 175.68 641.10 Td (or) Tj ET Q q 0 0 0 rg BT 183.83 641.10 Td (ganized ) Tj ET Q q 0 0 0 rg BT 217.43 641.10 Td (workforce.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 617.10 Td (e ) Tj ET Q q 0 0 0 rg BT 50.36 617.10 Td (consider ) Tj ET Q q 0 0 0 rg BT 85.52 617.10 Td (all ) Tj ET Q q 0 0 0 rg BT 96.80 617.10 Td (of ) Tj ET Q q 0 0 0 rg BT 106.42 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 119.92 617.10 Td (above ) Tj ET Q q 0 0 0 rg BT 145.08 617.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 173.57 617.10 Td (when ) Tj ET Q q 0 0 0 rg BT 196.51 617.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 246.12 617.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 279.61 617.10 Td (a ) Tj ET Q q 0 0 0 rg BT 285.33 617.10 Td (business ) Tj ET Q q 0 0 0 rg BT 320.51 617.10 Td (was ) Tj ET Q q 0 0 0 rg BT 337.34 617.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 373.05 617.10 Td (\(or ) Tj ET Q q 0 0 0 rg BT 386.00 617.10 Td (divested\) ) Tj ET Q q 0 0 0 rg BT 423.93 617.10 Td (as ) Tj ET Q q 0 0 0 rg BT 433.55 617.10 Td (well ) Tj ET Q q 0 0 0 rg BT 452.05 617.10 Td (as ) Tj ET Q q 0 0 0 rg BT 461.66 617.10 Td (the ) Tj ET Q q 0 0 0 rg BT 475.17 617.10 Td (compound's ) Tj ET Q q 0 0 0 rg BT 524.36 617.10 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (phase ) Tj ET Q q 0 0 0 rg BT 61.29 605.10 Td (if ) Tj ET Q q 0 0 0 rg BT 69.92 605.10 Td (no ) Tj ET Q q 0 0 0 rg BT 82.44 605.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 132.16 605.10 Td (products ) Tj ET Q q 0 0 0 rg BT 169.12 605.10 Td (are ) Tj ET Q q 0 0 0 rg BT 183.85 605.10 Td (involved. ) Tj ET Q q 0 0 0 rg BT 223.87 605.10 Td (For ) Tj ET Q q 0 0 0 rg BT 240.28 605.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 279.18 605.10 Td (in ) Tj ET Q q 0 0 0 rg BT 289.48 605.10 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 333.65 605.10 Td (our ) Tj ET Q q 0 0 0 rg BT 349.50 605.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 399.80 605.10 Td (of ) Tj ET Q q 0 0 0 rg BT 410.65 605.10 Td (IFM, ) Tj ET Q q 0 0 0 rg BT 433.45 605.10 Td (Cormorant, ) Tj ET Q q 0 0 0 rg BT 481.80 605.10 Td (Padlock, ) Tj ET Q q 0 0 0 rg BT 519.04 605.10 Td (Cardioxyl ) Tj ET Q q 0 0 0 rg BT 561.56 605.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 64.60 593.10 Td (during ) Tj ET Q q 0 0 0 rg BT 92.63 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 106.77 593.10 Td (past ) Tj ET Q q 0 0 0 rg BT 124.81 593.10 Td (three ) Tj ET Q q 0 0 0 rg BT 146.72 593.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 172.25 593.10 Td (we ) Tj ET Q q 0 0 0 rg BT 185.83 593.10 Td (concluded ) Tj ET Q q 0 0 0 rg BT 228.85 593.10 Td (that ) Tj ET Q q 0 0 0 rg BT 245.77 593.10 Td (no ) Tj ET Q q 0 0 0 rg BT 257.70 593.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 301.84 593.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 342.08 593.10 Td (were ) Tj ET Q q 0 0 0 rg BT 363.44 593.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 408.67 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 418.38 593.10 Td (us, ) Tj ET Q q 0 0 0 rg BT 431.69 593.10 Td (thus ) Tj ET Q q 0 0 0 rg BT 450.29 593.10 Td (the ) Tj ET Q q 0 0 0 rg BT 464.43 593.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 514.12 593.10 Td (were ) Tj ET Q q 0 0 0 rg BT 535.48 593.10 Td (accounted ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.10 581.10 Td (as ) Tj ET Q q 0 0 0 rg BT 60.87 581.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 82.74 581.10 Td (acquisitions. ) Tj ET Q q 0 0 0 rg BT 134.92 581.10 Td (As ) Tj ET Q q 0 0 0 rg BT 148.47 581.10 Td (a ) Tj ET Q q 0 0 0 rg BT 155.34 581.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 182.50 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 197.15 581.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 233.48 581.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 272.00 581.10 Td (to ) Tj ET Q q 0 0 0 rg BT 282.22 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 296.88 581.10 Td (lead ) Tj ET Q q 0 0 0 rg BT 315.97 581.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 377.28 581.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 425.83 581.10 Td (were ) Tj ET Q q 0 0 0 rg BT 447.70 581.10 Td (expensed ) Tj ET Q q 0 0 0 rg BT 487.34 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 504.22 581.10 Td (not ) Tj ET Q q 0 0 0 rg BT 519.44 581.10 Td (capitalized. ) Tj ET Q q 0 0 0 rg BT 567.68 581.10 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 73.19 569.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 117.33 569.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 173.12 569.10 Td (from ) Tj ET Q q 0 0 0 rg BT 194.48 569.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 231.39 569.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 287.46 569.10 Td (regulatory) Tj ET Q q 0 0 0 rg BT 327.91 569.10 Td (, ) Tj ET Q q 0 0 0 rg BT 332.33 569.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 369.24 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 385.60 569.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 433.06 569.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 477.75 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 494.11 569.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 541.57 569.10 Td (royalties ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (were ) Tj ET Q q 0 0 0 rg BT 58.87 557.10 Td (not ) Tj ET Q q 0 0 0 rg BT 75.09 557.10 Td (included ) Tj ET Q q 0 0 0 rg BT 112.96 557.10 Td (in ) Tj ET Q q 0 0 0 rg BT 124.18 557.10 Td (the ) Tj ET Q q 0 0 0 rg BT 139.84 557.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 178.81 557.10 Td (price. ) Tj ET Q q 0 0 0 rg BT 204.74 557.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 230.38 557.10 Td (to ) Tj ET Q q 0 0 0 rg BT 241.60 557.10 Td ("Item ) Tj ET Q q 0 0 0 rg BT 267.45 557.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 278.39 557.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 319.04 557.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 395.80 557.10 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.80 557.10 Td (. ) Tj ET Q q 0 0 0 rg BT 405.98 557.10 Td (Acquisitions ) Tj ET Q q 0 0 0 rg BT 459.98 557.10 Td (and ) Tj ET Q q 0 0 0 rg BT 477.86 557.10 Td (Divestitures" ) Tj ET Q q 0 0 0 rg BT 533.71 557.10 Td (for ) Tj ET Q q 0 0 0 rg BT 548.81 557.10 Td (further ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.10 Td (discussion ) Tj ET Q q 0 0 0 rg BT 80.17 545.10 Td (on ) Tj ET Q q 0 0 0 rg BT 92.67 545.10 Td (our ) Tj ET Q q 0 0 0 rg BT 108.50 545.10 Td (acquisitions. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.10 Td (Similarly) Tj ET Q q 0 0 0 rg BT 72.57 521.10 Td (, ) Tj ET Q q 0 0 0 rg BT 77.56 521.10 Td (in ) Tj ET Q q 0 0 0 rg BT 87.83 521.10 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 131.97 521.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 180.57 521.10 Td (of ) Tj ET Q q 0 0 0 rg BT 191.39 521.10 Td (our ) Tj ET Q q 0 0 0 rg BT 207.21 521.10 Td (small ) Tj ET Q q 0 0 0 rg BT 231.36 521.10 Td (molecule ) Tj ET Q q 0 0 0 rg BT 270.50 521.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 331.30 521.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 375.45 521.10 Td (in ) Tj ET Q q 0 0 0 rg BT 385.72 521.10 Td (Swords, ) Tj ET Q q 0 0 0 rg BT 420.71 521.10 Td (Ireland, ) Tj ET Q q 0 0 0 rg BT 454.02 521.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 515.38 521.10 Td (HIV) Tj ET Q q 0 0 0 rg BT 532.98 521.10 Td ( ) Tj ET Q q 0 0 0 rg BT 535.47 521.10 Td (medicines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.10 Td (business, ) Tj ET Q q 0 0 0 rg BT 76.00 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 91.82 509.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 137.65 509.10 Td (comprising ) Tj ET Q q 0 0 0 rg BT 186.25 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 202.08 509.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 236.78 509.10 Td (with ) Tj ET Q q 0 0 0 rg BT 258.16 509.10 Td (Reckitt, ) Tj ET Q q 0 0 0 rg BT 293.15 509.10 Td (the ) Tj ET Q q 0 0 0 rg BT 308.97 509.10 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 354.24 509.10 Td (Company) Tj ET Q q 0 0 0 rg BT 392.47 509.10 Td (, ) Tj ET Q q 0 0 0 rg BT 398.32 509.10 Td (V) Tj ET Q q 0 0 0 rg BT 404.43 509.10 Td (aleant ) Tj ET Q q 0 0 0 rg BT 431.91 509.10 Td (Pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 501.05 509.10 Td (International, ) Tj ET Q q 0 0 0 rg BT 558.25 509.10 Td (Inc., ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 497.10 Td (Erbitux* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 73.59 497.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 90.62 497.10 Td (Ixempra*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 128.94 497.10 Td (, ) Tj ET Q q 0 0 0 rg BT 134.03 497.10 Td (we ) Tj ET Q q 0 0 0 rg BT 148.29 497.10 Td (concluded ) Tj ET Q q 0 0 0 rg BT 191.97 497.10 Td (that ) Tj ET Q q 0 0 0 rg BT 209.56 497.10 Td (all ) Tj ET Q q 0 0 0 rg BT 222.15 497.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 263.61 497.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 290.65 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 307.68 497.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 348.59 497.10 Td (were ) Tj ET Q q 0 0 0 rg BT 370.61 497.10 Td (transferred, ) Tj ET Q q 0 0 0 rg BT 419.01 497.10 Td (and ) Tj ET Q q 0 0 0 rg BT 436.04 497.10 Td (consequently ) Tj ET Q q 0 0 0 rg BT 491.40 497.10 Td (the ) Tj ET Q q 0 0 0 rg BT 506.21 497.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 556.57 497.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 79.67 485.10 Td (for ) Tj ET Q q 0 0 0 rg BT 94.46 485.10 Td (as ) Tj ET Q q 0 0 0 rg BT 105.93 485.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 128.51 485.10 Td (of ) Tj ET Q q 0 0 0 rg BT 139.97 485.10 Td (businesses, ) Tj ET Q q 0 0 0 rg BT 187.83 485.10 Td (which ) Tj ET Q q 0 0 0 rg BT 215.40 485.10 Td (resulted ) Tj ET Q q 0 0 0 rg BT 250.20 485.10 Td (in ) Tj ET Q q 0 0 0 rg BT 261.11 485.10 Td (the ) Tj ET Q q 0 0 0 rg BT 276.46 485.10 Td (allocation ) Tj ET Q q 0 0 0 rg BT 319.03 485.10 Td (of ) Tj ET Q q 0 0 0 rg BT 330.50 485.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 369.19 485.10 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.52 485.10 Td ($12 ) Tj ET Q q 0 0 0 rg BT 390.65 485.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.55 485.10 Td ( ) Tj ET Q q 0 0 0 rg BT 422.68 485.10 Td (in ) Tj ET Q q 0 0 0 rg BT 433.60 485.10 Td (2017, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.23 485.10 Td ($98 ) Tj ET Q q 0 0 0 rg BT 477.37 485.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 506.26 485.10 Td ( ) Tj ET Q q 0 0 0 rg BT 509.40 485.10 Td (in ) Tj ET Q q 0 0 0 rg BT 520.31 485.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 543.45 485.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.02 485.10 Td ($73 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 67.19 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 77.26 473.10 Td (2015\) ) Tj ET Q q 0 0 0 rg BT 102.88 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 112.96 473.10 Td (the ) Tj ET Q q 0 0 0 rg BT 127.47 473.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 163.08 473.10 Td (value ) Tj ET Q q 0 0 0 rg BT 187.03 473.10 Td (of ) Tj ET Q q 0 0 0 rg BT 197.66 473.10 Td (the ) Tj ET Q q 0 0 0 rg BT 212.17 473.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 256.68 473.10 Td (in ) Tj ET Q q 0 0 0 rg BT 266.76 473.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 317.37 473.10 Td (the ) Tj ET Q q 0 0 0 rg BT 331.88 473.10 Td (gain ) Tj ET Q q 0 0 0 rg BT 351.40 473.10 Td (on ) Tj ET Q q 0 0 0 rg BT 363.69 473.10 Td (sale. ) Tj ET Q q 0 0 0 rg BT 384.03 473.10 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 430.77 473.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 468.60 473.10 Td (related ) Tj ET Q q 0 0 0 rg BT 498.10 473.10 Td (to ) Tj ET Q q 0 0 0 rg BT 508.17 473.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 556.57 473.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (not ) Tj ET Q q 0 0 0 rg BT 51.60 461.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 98.29 461.10 Td (until ) Tj ET Q q 0 0 0 rg BT 119.45 461.10 Td (realized. ) Tj ET Q q 0 0 0 rg BT 156.21 461.10 Td (W) Tj ET Q q 0 0 0 rg BT 164.84 461.10 Td (e ) Tj ET Q q 0 0 0 rg BT 172.11 461.10 Td (also ) Tj ET Q q 0 0 0 rg BT 191.04 461.10 Td (concluded ) Tj ET Q q 0 0 0 rg BT 234.96 461.10 Td (that ) Tj ET Q q 0 0 0 rg BT 252.78 461.10 Td (not ) Tj ET Q q 0 0 0 rg BT 268.38 461.10 Td (all ) Tj ET Q q 0 0 0 rg BT 281.20 461.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 308.47 461.10 Td (and ) Tj ET Q q 0 0 0 rg BT 325.73 461.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 370.77 461.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 411.91 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 422.51 461.10 Td (be ) Tj ET Q q 0 0 0 rg BT 434.77 461.10 Td (capable ) Tj ET Q q 0 0 0 rg BT 468.13 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 479.28 461.10 Td (generating ) Tj ET Q q 0 0 0 rg BT 524.31 461.10 Td (outputs ) Tj ET Q q 0 0 0 rg BT 556.58 461.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 82.37 449.10 Td (in ) Tj ET Q q 0 0 0 rg BT 93.22 449.10 Td (our ) Tj ET Q q 0 0 0 rg BT 109.61 449.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 164.89 449.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 221.82 449.10 Td (with ) Tj ET Q q 0 0 0 rg BT 242.67 449.10 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 274.62 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 292.12 449.10 Td (Roche, ) Tj ET Q q 0 0 0 rg BT 323.24 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 340.74 449.10 Td (consequently ) Tj ET Q q 0 0 0 rg BT 396.57 449.10 Td (these ) Tj ET Q q 0 0 0 rg BT 420.18 449.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 471.01 449.10 Td (were ) Tj ET Q q 0 0 0 rg BT 493.51 449.10 Td (not ) Tj ET Q q 0 0 0 rg BT 509.35 449.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 552.95 449.10 Td (for ) Tj ET Q q 0 0 0 rg BT 567.68 449.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 57.94 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 68.77 437.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 113.49 437.10 Td (in ) Tj ET Q q 0 0 0 rg BT 123.77 437.10 Td (2017.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (Long-lived ) Tj ET Q q 0 0 0 rg BT 82.56 413.10 Td (Assets) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 390.1669921875 m 198.294921875 390.1669921875 l s q 0 0 0 rg BT 36.00 391.50 Td (Other Intangible ) Tj ET Q q 0 0 0 rg BT 105.25 391.50 Td (Assets, including IPRD) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.90 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.47 369.90 Td (intangible ) Tj ET Q q 0 0 0 rg BT 104.15 369.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 130.18 369.90 Td (were ) Tj ET Q q 0 0 0 rg BT 152.30 369.90 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.30 369.90 Td (1.2 ) Tj ET Q q 0 0 0 rg BT 172.50 369.90 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 198.61 369.90 Td ( ) Tj ET Q q 0 0 0 rg BT 201.31 369.90 Td (at ) Tj ET Q q 0 0 0 rg BT 211.23 369.90 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 270.01 369.90 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.01 369.90 Td (, ) Tj ET Q q 0 0 0 rg BT 295.20 369.90 Td (including ) Tj ET Q q 0 0 0 rg BT 335.67 369.90 Td (licenses ) Tj ET Q q 0 0 0 rg BT 370.02 369.90 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.35 369.90 Td ($254 ) Tj ET Q q 0 0 0 rg BT 396.05 369.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.94 369.90 Td ( ) Tj ET Q q 0 0 0 rg BT 427.64 369.90 Td (of ) Tj ET Q q 0 0 0 rg BT 438.67 369.90 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.80 369.90 Td ($152 ) Tj ET Q q 0 0 0 rg BT 488.50 369.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 517.39 369.90 Td ( ) Tj ET Q q 0 0 0 rg BT 520.09 369.90 Td (is ) Tj ET Q q 0 0 0 rg BT 529.45 369.90 Td (allocated ) Tj ET Q q 0 0 0 rg BT 568.24 369.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.90 Td (unapproved ) Tj ET Q q 0 0 0 rg BT 84.68 357.90 Td (products\), ) Tj ET Q q 0 0 0 rg BT 126.42 357.90 Td (developed ) Tj ET Q q 0 0 0 rg BT 168.98 357.90 Td (technology ) Tj ET Q q 0 0 0 rg BT 214.89 357.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 239.14 357.90 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 242.47 357.90 Td ($565 ) Tj ET Q q 0 0 0 rg BT 263.94 357.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.83 357.90 Td (\), ) Tj ET Q q 0 0 0 rg BT 300.13 357.90 Td (capitalized ) Tj ET Q q 0 0 0 rg BT 344.91 357.90 Td (software ) Tj ET Q q 0 0 0 rg BT 380.81 357.90 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.14 357.90 Td ($359 ) Tj ET Q q 0 0 0 rg BT 405.61 357.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.50 357.90 Td (\) ) Tj ET Q q 0 0 0 rg BT 439.30 357.90 Td (and ) Tj ET Q q 0 0 0 rg BT 455.21 357.90 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 479.47 357.90 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.80 357.90 Td ($32 ) Tj ET Q q 0 0 0 rg BT 499.27 357.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.16 357.90 Td (\). ) Tj ET Q q 0 0 0 rg BT 535.46 357.90 Td (Intangible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 61.31 345.90 Td (are ) Tj ET Q q 0 0 0 rg BT 75.50 345.90 Td (assessed ) Tj ET Q q 0 0 0 rg BT 111.36 345.90 Td (for ) Tj ET Q q 0 0 0 rg BT 125.00 345.90 Td (impairment ) Tj ET Q q 0 0 0 rg BT 173.08 345.90 Td (whenever ) Tj ET Q q 0 0 0 rg BT 213.92 345.90 Td (current ) Tj ET Q q 0 0 0 rg BT 244.22 345.90 Td (facts ) Tj ET Q q 0 0 0 rg BT 265.08 345.90 Td (or ) Tj ET Q q 0 0 0 rg BT 275.39 345.90 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 334.01 345.90 Td (warrant ) Tj ET Q q 0 0 0 rg BT 366.52 345.90 Td (a ) Tj ET Q q 0 0 0 rg BT 372.94 345.90 Td (review) Tj ET Q q 0 0 0 rg BT 399.50 345.90 Td (, ) Tj ET Q q 0 0 0 rg BT 403.98 345.90 Td (although ) Tj ET Q q 0 0 0 rg BT 440.96 345.90 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 465.72 345.90 Td (is ) Tj ET Q q 0 0 0 rg BT 474.37 345.90 Td (assessed ) Tj ET Q q 0 0 0 rg BT 510.23 345.90 Td (at ) Tj ET Q q 0 0 0 rg BT 519.43 345.90 Td (least ) Tj ET Q q 0 0 0 rg BT 539.73 345.90 Td (annually) Tj ET Q q 0 0 0 rg BT 573.52 345.90 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.90 Td (Intangible ) Tj ET Q q 0 0 0 rg BT 78.49 333.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 103.77 333.90 Td (are ) Tj ET Q q 0 0 0 rg BT 117.93 333.90 Td (highly ) Tj ET Q q 0 0 0 rg BT 145.43 333.90 Td (vulnerable ) Tj ET Q q 0 0 0 rg BT 189.59 333.90 Td (to ) Tj ET Q q 0 0 0 rg BT 199.31 333.90 Td (impairment ) Tj ET Q q 0 0 0 rg BT 247.36 333.90 Td (char) Tj ET Q q 0 0 0 rg BT 264.39 333.90 Td (ges, ) Tj ET Q q 0 0 0 rg BT 282.17 333.90 Td (particularly ) Tj ET Q q 0 0 0 rg BT 330.21 333.90 Td (newly ) Tj ET Q q 0 0 0 rg BT 356.60 333.90 Td (acquired ) Tj ET Q q 0 0 0 rg BT 392.97 333.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 418.25 333.90 Td (for ) Tj ET Q q 0 0 0 rg BT 431.86 333.90 Td (recently ) Tj ET Q q 0 0 0 rg BT 466.01 333.90 Td (launched ) Tj ET Q q 0 0 0 rg BT 504.05 333.90 Td (products ) Tj ET Q q 0 0 0 rg BT 540.44 333.90 Td (or ) Tj ET Q q 0 0 0 rg BT 550.72 333.90 Td (IPRD. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 321.90 Td (These ) Tj ET Q q 0 0 0 rg BT 62.22 321.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 87.89 321.90 Td (are ) Tj ET Q q 0 0 0 rg BT 102.45 321.90 Td (initially ) Tj ET Q q 0 0 0 rg BT 135.90 321.90 Td (measured ) Tj ET Q q 0 0 0 rg BT 176.56 321.90 Td (at ) Tj ET Q q 0 0 0 rg BT 186.12 321.90 Td (fair ) Tj ET Q q 0 0 0 rg BT 202.34 321.90 Td (value ) Tj ET Q q 0 0 0 rg BT 226.34 321.90 Td (and ) Tj ET Q q 0 0 0 rg BT 243.12 321.90 Td (therefore ) Tj ET Q q 0 0 0 rg BT 281.55 321.90 Td (any ) Tj ET Q q 0 0 0 rg BT 298.33 321.90 Td (reduction ) Tj ET Q q 0 0 0 rg BT 338.44 321.90 Td (in ) Tj ET Q q 0 0 0 rg BT 348.56 321.90 Td (expectations ) Tj ET Q q 0 0 0 rg BT 400.88 321.90 Td (used ) Tj ET Q q 0 0 0 rg BT 421.56 321.90 Td (in ) Tj ET Q q 0 0 0 rg BT 431.68 321.90 Td (the ) Tj ET Q q 0 0 0 rg BT 446.24 321.90 Td (valuations ) Tj ET Q q 0 0 0 rg BT 489.69 321.90 Td (could ) Tj ET Q q 0 0 0 rg BT 514.25 321.90 Td (potentially ) Tj ET Q q 0 0 0 rg BT 559.36 321.90 Td (lead ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.90 Td (to ) Tj ET Q q 0 0 0 rg BT 45.96 309.90 Td (impairment. ) Tj ET Q q 0 0 0 rg BT 96.75 309.90 Td (Some ) Tj ET Q q 0 0 0 rg BT 121.71 309.90 Td (of ) Tj ET Q q 0 0 0 rg BT 132.23 309.90 Td (the ) Tj ET Q q 0 0 0 rg BT 146.63 309.90 Td (more ) Tj ET Q q 0 0 0 rg BT 169.36 309.90 Td (common ) Tj ET Q q 0 0 0 rg BT 206.54 309.90 Td (potential ) Tj ET Q q 0 0 0 rg BT 243.71 309.90 Td (risks ) Tj ET Q q 0 0 0 rg BT 264.79 309.90 Td (leading ) Tj ET Q q 0 0 0 rg BT 296.41 309.90 Td (to ) Tj ET Q q 0 0 0 rg BT 306.37 309.90 Td (impairment ) Tj ET Q q 0 0 0 rg BT 354.66 309.90 Td (include ) Tj ET Q q 0 0 0 rg BT 386.28 309.90 Td (competition, ) Tj ET Q q 0 0 0 rg BT 438.73 309.90 Td (earlier ) Tj ET Q q 0 0 0 rg BT 466.45 309.90 Td (than ) Tj ET Q q 0 0 0 rg BT 485.85 309.90 Td (expected ) Tj ET Q q 0 0 0 rg BT 523.57 309.90 Td (LOE, ) Tj ET Q q 0 0 0 rg BT 547.69 309.90 Td (pricing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.90 Td (pressures, ) Tj ET Q q 0 0 0 rg BT 77.91 297.90 Td (adverse ) Tj ET Q q 0 0 0 rg BT 110.65 297.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 153.95 297.90 Td (changes ) Tj ET Q q 0 0 0 rg BT 188.35 297.90 Td (or ) Tj ET Q q 0 0 0 rg BT 198.89 297.90 Td (clinical ) Tj ET Q q 0 0 0 rg BT 230.52 297.90 Td (study ) Tj ET Q q 0 0 0 rg BT 254.39 297.90 Td (results, ) Tj ET Q q 0 0 0 rg BT 285.20 297.90 Td (delay ) Tj ET Q q 0 0 0 rg BT 309.05 297.90 Td (or ) Tj ET Q q 0 0 0 rg BT 319.58 297.90 Td (failure ) Tj ET Q q 0 0 0 rg BT 347.88 297.90 Td (to ) Tj ET Q q 0 0 0 rg BT 357.86 297.90 Td (obtain ) Tj ET Q q 0 0 0 rg BT 385.05 297.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 428.35 297.90 Td (approval ) Tj ET Q q 0 0 0 rg BT 465.54 297.90 Td (and ) Tj ET Q q 0 0 0 rg BT 482.18 297.90 Td (additional ) Tj ET Q q 0 0 0 rg BT 524.37 297.90 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.90 Td (costs, ) Tj ET Q q 0 0 0 rg BT 62.13 285.90 Td (inability ) Tj ET Q q 0 0 0 rg BT 99.09 285.90 Td (to ) Tj ET Q q 0 0 0 rg BT 110.50 285.90 Td (achieve ) Tj ET Q q 0 0 0 rg BT 144.67 285.90 Td (expected ) Tj ET Q q 0 0 0 rg BT 183.83 285.90 Td (syner) Tj ET Q q 0 0 0 rg BT 205.31 285.90 Td (gies, ) Tj ET Q q 0 0 0 rg BT 227.55 285.90 Td (higher ) Tj ET Q q 0 0 0 rg BT 256.73 285.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 298.13 285.90 Td (costs, ) Tj ET Q q 0 0 0 rg BT 324.26 285.90 Td (changes ) Tj ET Q q 0 0 0 rg BT 360.10 285.90 Td (in ) Tj ET Q q 0 0 0 rg BT 371.51 285.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 387.36 285.90 Td (laws ) Tj ET Q q 0 0 0 rg BT 409.32 285.90 Td (and ) Tj ET Q q 0 0 0 rg BT 427.39 285.90 Td (other ) Tj ET Q q 0 0 0 rg BT 451.57 285.90 Td (macro-economic ) Tj ET Q q 0 0 0 rg BT 522.39 285.90 Td (changes. ) Tj ET Q q 0 0 0 rg BT 560.46 285.90 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.90 Td (complexity ) Tj ET Q q 0 0 0 rg BT 83.49 273.90 Td (in ) Tj ET Q q 0 0 0 rg BT 93.77 273.90 Td (estimating ) Tj ET Q q 0 0 0 rg BT 137.93 273.90 Td (the ) Tj ET Q q 0 0 0 rg BT 152.65 273.90 Td (fair ) Tj ET Q q 0 0 0 rg BT 169.02 273.90 Td (value ) Tj ET Q q 0 0 0 rg BT 193.18 273.90 Td (of ) Tj ET Q q 0 0 0 rg BT 204.01 273.90 Td (intangible ) Tj ET Q q 0 0 0 rg BT 246.50 273.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 272.33 273.90 Td (in ) Tj ET Q q 0 0 0 rg BT 282.61 273.90 Td (connection ) Tj ET Q q 0 0 0 rg BT 328.98 273.90 Td (with ) Tj ET Q q 0 0 0 rg BT 349.26 273.90 Td (an ) Tj ET Q q 0 0 0 rg BT 361.20 273.90 Td (impairment ) Tj ET Q q 0 0 0 rg BT 409.79 273.90 Td (test ) Tj ET Q q 0 0 0 rg BT 426.18 273.90 Td (is ) Tj ET Q q 0 0 0 rg BT 435.35 273.90 Td (similar ) Tj ET Q q 0 0 0 rg BT 465.62 273.90 Td (to ) Tj ET Q q 0 0 0 rg BT 475.90 273.90 Td (the ) Tj ET Q q 0 0 0 rg BT 490.62 273.90 Td (initial ) Tj ET Q q 0 0 0 rg BT 516.45 273.90 Td (valuation.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 249.90 Td (Considering ) Tj ET Q q 0 0 0 rg BT 87.52 249.90 Td (the ) Tj ET Q q 0 0 0 rg BT 102.37 249.90 Td (high ) Tj ET Q q 0 0 0 rg BT 122.78 249.90 Td (risk ) Tj ET Q q 0 0 0 rg BT 140.41 249.90 Td (nature ) Tj ET Q q 0 0 0 rg BT 168.03 249.90 Td (of ) Tj ET Q q 0 0 0 rg BT 178.99 249.90 Td (research ) Tj ET Q q 0 0 0 rg BT 214.93 249.90 Td (and ) Tj ET Q q 0 0 0 rg BT 232.00 249.90 Td (development ) Tj ET Q q 0 0 0 rg BT 286.28 249.90 Td (and ) Tj ET Q q 0 0 0 rg BT 303.35 249.90 Td (the ) Tj ET Q q 0 0 0 rg BT 318.20 249.90 Td (industry’) Tj ET Q q 0 0 0 rg BT 353.75 249.90 Td (s ) Tj ET Q q 0 0 0 rg BT 360.28 249.90 Td (success ) Tj ET Q q 0 0 0 rg BT 392.90 249.90 Td (rate ) Tj ET Q q 0 0 0 rg BT 410.52 249.90 Td (of ) Tj ET Q q 0 0 0 rg BT 421.48 249.90 Td (bringing ) Tj ET Q q 0 0 0 rg BT 458.00 249.90 Td (developmental ) Tj ET Q q 0 0 0 rg BT 519.50 249.90 Td (compounds ) Tj ET Q q 0 0 0 rg BT 568.24 249.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 237.90 Td (market, ) Tj ET Q q 0 0 0 rg BT 68.79 237.90 Td (impairment ) Tj ET Q q 0 0 0 rg BT 117.41 237.90 Td (char) Tj ET Q q 0 0 0 rg BT 134.44 237.90 Td (ges ) Tj ET Q q 0 0 0 rg BT 150.30 237.90 Td (are ) Tj ET Q q 0 0 0 rg BT 165.03 237.90 Td (likely ) Tj ET Q q 0 0 0 rg BT 190.33 237.90 Td (to ) Tj ET Q q 0 0 0 rg BT 200.63 237.90 Td (occur ) Tj ET Q q 0 0 0 rg BT 225.37 237.90 Td (in ) Tj ET Q q 0 0 0 rg BT 235.67 237.90 Td (future ) Tj ET Q q 0 0 0 rg BT 262.07 237.90 Td (periods. ) Tj ET Q q 0 0 0 rg BT 296.35 237.90 Td (W) Tj ET Q q 0 0 0 rg BT 304.99 237.90 Td (e ) Tj ET Q q 0 0 0 rg BT 311.96 237.90 Td (recognized ) Tj ET Q q 0 0 0 rg BT 358.34 237.90 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 365.31 237.90 Td ($75 ) Tj ET Q q 0 0 0 rg BT 382.83 237.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.73 237.90 Td ( ) Tj ET Q q 0 0 0 rg BT 414.25 237.90 Td (char) Tj ET Q q 0 0 0 rg BT 431.28 237.90 Td (ge ) Tj ET Q q 0 0 0 rg BT 443.24 237.90 Td (in ) Tj ET Q q 0 0 0 rg BT 453.55 237.90 Td (2017 ) Tj ET Q q 0 0 0 rg BT 476.07 237.90 Td (for ) Tj ET Q q 0 0 0 rg BT 490.26 237.90 Td (F-Star ) Tj ET Q q 0 0 0 rg BT 517.23 237.90 Td (Alpha's ) Tj ET Q q 0 0 0 rg BT 549.89 237.90 Td (FS102 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 225.90 Td (which ) Tj ET Q q 0 0 0 rg BT 62.97 225.90 Td (was ) Tj ET Q q 0 0 0 rg BT 81.05 225.90 Td (in ) Tj ET Q q 0 0 0 rg BT 91.36 225.90 Td (Phase ) Tj ET Q q 0 0 0 rg BT 117.23 225.90 Td (I ) Tj ET Q q 0 0 0 rg BT 123.09 225.90 Td (development ) Tj ET Q q 0 0 0 rg BT 177.27 225.90 Td (for ) Tj ET Q q 0 0 0 rg BT 191.46 225.90 Td (the ) Tj ET Q q 0 0 0 rg BT 206.21 225.90 Td (treatment ) Tj ET Q q 0 0 0 rg BT 246.50 225.90 Td (of ) Tj ET Q q 0 0 0 rg BT 257.36 225.90 Td (breast ) Tj ET Q q 0 0 0 rg BT 283.77 225.90 Td (and ) Tj ET Q q 0 0 0 rg BT 300.74 225.90 Td (gastric ) Tj ET Q q 0 0 0 rg BT 329.93 225.90 Td (cancer ) Tj ET Q q 0 0 0 rg BT 358.54 225.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.51 225.90 Td ($160 ) Tj ET Q q 0 0 0 rg BT 398.05 225.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.94 225.90 Td ( ) Tj ET Q q 0 0 0 rg BT 429.47 225.90 Td (in ) Tj ET Q q 0 0 0 rg BT 439.78 225.90 Td (2015 ) Tj ET Q q 0 0 0 rg BT 462.31 225.90 Td (for ) Tj ET Q q 0 0 0 rg BT 476.50 225.90 Td (BMS-986020 ) Tj ET Q q 0 0 0 rg BT 533.49 225.90 Td (which ) Tj ET Q q 0 0 0 rg BT 560.46 225.90 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.90 Td (in ) Tj ET Q q 0 0 0 rg BT 46.57 213.90 Td (Phase ) Tj ET Q q 0 0 0 rg BT 72.70 213.90 Td (II ) Tj ET Q q 0 0 0 rg BT 82.15 213.90 Td (development ) Tj ET Q q 0 0 0 rg BT 136.60 213.90 Td (for ) Tj ET Q q 0 0 0 rg BT 151.06 213.90 Td (treatment ) Tj ET Q q 0 0 0 rg BT 191.61 213.90 Td (of ) Tj ET Q q 0 0 0 rg BT 202.74 213.90 Td (IPF) Tj ET Q q 0 0 0 rg BT 216.39 213.90 Td (. ) Tj ET Q q 0 0 0 rg BT 221.68 213.90 Td (For ) Tj ET Q q 0 0 0 rg BT 238.37 213.90 Td (discussion ) Tj ET Q q 0 0 0 rg BT 282.84 213.90 Td (on ) Tj ET Q q 0 0 0 rg BT 295.63 213.90 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 321.21 213.90 Td (impairments, ) Tj ET Q q 0 0 0 rg BT 376.50 213.90 Td ( ) Tj ET Q q 0 0 0 rg BT 379.29 213.90 Td (refer ) Tj ET Q q 0 0 0 rg BT 400.95 213.90 Td (to ) Tj ET Q q 0 0 0 rg BT 411.53 213.90 Td (“Item ) Tj ET Q q 0 0 0 rg BT 437.09 213.90 Td (8. ) Tj ET Q q 0 0 0 rg BT 447.38 213.90 Td (Financial ) Tj ET Q q 0 0 0 rg BT 487.39 213.90 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.50 213.90 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.50 213.90 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.90 Td (Goodwill ) Tj ET Q q 0 0 0 rg BT 76.28 201.90 Td (and ) Tj ET Q q 0 0 0 rg BT 93.22 201.90 Td (Other ) Tj ET Q q 0 0 0 rg BT 118.49 201.90 Td (Intangible ) Tj ET Q q 0 0 0 rg BT 160.98 201.90 Td (Assets.") Tj ET Q endstream endobj 101 0 obj <> endobj 102 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (50) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 160.6142578125 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Pr) Tj ET Q q 0 0 0 rg BT 45.63 749.10 Td (operty) Tj ET Q q 0 0 0 rg BT 70.62 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 75.62 749.10 Td (Plant ) Tj ET Q q 0 0 0 rg BT 99.79 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 117.29 749.10 Td (Equipment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 727.50 Td (Property) Tj ET Q q 0 0 0 rg BT 69.79 727.50 Td (, ) Tj ET Q q 0 0 0 rg BT 74.72 727.50 Td (plant ) Tj ET Q q 0 0 0 rg BT 97.14 727.50 Td (and ) Tj ET Q q 0 0 0 rg BT 114.00 727.50 Td (equipment ) Tj ET Q q 0 0 0 rg BT 158.64 727.50 Td (is ) Tj ET Q q 0 0 0 rg BT 167.74 727.50 Td (tested ) Tj ET Q q 0 0 0 rg BT 193.49 727.50 Td (for ) Tj ET Q q 0 0 0 rg BT 207.58 727.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 256.10 727.50 Td (whenever ) Tj ET Q q 0 0 0 rg BT 297.40 727.50 Td (current ) Tj ET Q q 0 0 0 rg BT 328.14 727.50 Td (facts ) Tj ET Q q 0 0 0 rg BT 349.44 727.50 Td (or ) Tj ET Q q 0 0 0 rg BT 360.20 727.50 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 419.27 727.50 Td (require ) Tj ET Q q 0 0 0 rg BT 450.01 727.50 Td (a ) Tj ET Q q 0 0 0 rg BT 456.87 727.50 Td (review ) Tj ET Q q 0 0 0 rg BT 486.51 727.50 Td (including ) Tj ET Q q 0 0 0 rg BT 526.71 727.50 Td (whether ) Tj ET Q q 0 0 0 rg BT 561.34 727.50 Td (it ) Tj ET Q q 0 0 0 rg BT 569.33 727.50 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 715.50 Td (more ) Tj ET Q q 0 0 0 rg BT 59.36 715.50 Td (likely ) Tj ET Q q 0 0 0 rg BT 84.96 715.50 Td (than ) Tj ET Q q 0 0 0 rg BT 104.99 715.50 Td (not ) Tj ET Q q 0 0 0 rg BT 120.58 715.50 Td (that ) Tj ET Q q 0 0 0 rg BT 138.40 715.50 Td (the ) Tj ET Q q 0 0 0 rg BT 153.43 715.50 Td (asset ) Tj ET Q q 0 0 0 rg BT 175.69 715.50 Td (will ) Tj ET Q q 0 0 0 rg BT 194.06 715.50 Td (be ) Tj ET Q q 0 0 0 rg BT 206.32 715.50 Td (disposed ) Tj ET Q q 0 0 0 rg BT 244.13 715.50 Td (of ) Tj ET Q q 0 0 0 rg BT 255.28 715.50 Td (prior ) Tj ET Q q 0 0 0 rg BT 277.54 715.50 Td (to ) Tj ET Q q 0 0 0 rg BT 288.13 715.50 Td (its ) Tj ET Q q 0 0 0 rg BT 300.40 715.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 341.54 715.50 Td (remaining ) Tj ET Q q 0 0 0 rg BT 384.90 715.50 Td (useful ) Tj ET Q q 0 0 0 rg BT 412.15 715.50 Td (life. ) Tj ET Q q 0 0 0 rg BT 430.17 715.50 Td (Additionally) Tj ET Q q 0 0 0 rg BT 480.08 715.50 Td (, ) Tj ET Q q 0 0 0 rg BT 485.39 715.50 Td (these ) Tj ET Q q 0 0 0 rg BT 508.76 715.50 Td (long-lived ) Tj ET Q q 0 0 0 rg BT 552.68 715.50 Td (assets ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 703.50 Td (are ) Tj ET Q q 0 0 0 rg BT 50.41 703.50 Td (periodically ) Tj ET Q q 0 0 0 rg BT 100.38 703.50 Td (reviewed ) Tj ET Q q 0 0 0 rg BT 139.23 703.50 Td (to ) Tj ET Q q 0 0 0 rg BT 149.22 703.50 Td (determine ) Tj ET Q q 0 0 0 rg BT 191.41 703.50 Td (if ) Tj ET Q q 0 0 0 rg BT 199.72 703.50 Td (any ) Tj ET Q q 0 0 0 rg BT 216.37 703.50 Td (change ) Tj ET Q q 0 0 0 rg BT 246.89 703.50 Td (in ) Tj ET Q q 0 0 0 rg BT 256.87 703.50 Td (facts ) Tj ET Q q 0 0 0 rg BT 277.96 703.50 Td (or ) Tj ET Q q 0 0 0 rg BT 288.50 703.50 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 347.34 703.50 Td (would ) Tj ET Q q 0 0 0 rg BT 374.55 703.50 Td (result ) Tj ET Q q 0 0 0 rg BT 398.97 703.50 Td (in ) Tj ET Q q 0 0 0 rg BT 408.96 703.50 Td (a ) Tj ET Q q 0 0 0 rg BT 415.60 703.50 Td (change ) Tj ET Q q 0 0 0 rg BT 446.13 703.50 Td (to ) Tj ET Q q 0 0 0 rg BT 456.11 703.50 Td (the ) Tj ET Q q 0 0 0 rg BT 470.54 703.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 511.06 703.50 Td (useful ) Tj ET Q q 0 0 0 rg BT 537.71 703.50 Td (life ) Tj ET Q q 0 0 0 rg BT 553.24 703.50 Td (of ) Tj ET Q q 0 0 0 rg BT 563.78 703.50 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 691.50 Td (asset, ) Tj ET Q q 0 0 0 rg BT 60.71 691.50 Td (possibly ) Tj ET Q q 0 0 0 rg BT 96.82 691.50 Td (resulting ) Tj ET Q q 0 0 0 rg BT 134.59 691.50 Td (in ) Tj ET Q q 0 0 0 rg BT 145.14 691.50 Td (the ) Tj ET Q q 0 0 0 rg BT 160.13 691.50 Td (acceleration ) Tj ET Q q 0 0 0 rg BT 211.20 691.50 Td (of ) Tj ET Q q 0 0 0 rg BT 222.30 691.50 Td (depreciation. ) Tj ET Q q 0 0 0 rg BT 276.99 691.50 Td (If ) Tj ET Q q 0 0 0 rg BT 286.43 691.50 Td (such ) Tj ET Q q 0 0 0 rg BT 307.53 691.50 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 366.94 691.50 Td (exist, ) Tj ET Q q 0 0 0 rg BT 391.10 691.50 Td (an ) Tj ET Q q 0 0 0 rg BT 403.31 691.50 Td (estimate ) Tj ET Q q 0 0 0 rg BT 439.40 691.50 Td (of ) Tj ET Q q 0 0 0 rg BT 450.51 691.50 Td (undiscounted ) Tj ET Q q 0 0 0 rg BT 506.60 691.50 Td (future ) Tj ET Q q 0 0 0 rg BT 533.25 691.50 Td (cash ) Tj ET Q q 0 0 0 rg BT 553.79 691.50 Td (flows ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 679.50 Td (generated ) Tj ET Q q 0 0 0 rg BT 76.83 679.50 Td (by ) Tj ET Q q 0 0 0 rg BT 88.80 679.50 Td (the ) Tj ET Q q 0 0 0 rg BT 102.98 679.50 Td (asset, ) Tj ET Q q 0 0 0 rg BT 126.88 679.50 Td (or ) Tj ET Q q 0 0 0 rg BT 137.18 679.50 Td (the ) Tj ET Q q 0 0 0 rg BT 151.37 679.50 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 198.86 679.50 Td (grouping ) Tj ET Q q 0 0 0 rg BT 236.94 679.50 Td (of ) Tj ET Q q 0 0 0 rg BT 247.24 679.50 Td (assets, ) Tj ET Q q 0 0 0 rg BT 275.03 679.50 Td (is ) Tj ET Q q 0 0 0 rg BT 283.67 679.50 Td (compared ) Tj ET Q q 0 0 0 rg BT 325.06 679.50 Td (to ) Tj ET Q q 0 0 0 rg BT 334.81 679.50 Td (the ) Tj ET Q q 0 0 0 rg BT 348.99 679.50 Td (carrying ) Tj ET Q q 0 0 0 rg BT 384.27 679.50 Td (value ) Tj ET Q q 0 0 0 rg BT 407.89 679.50 Td (to ) Tj ET Q q 0 0 0 rg BT 417.64 679.50 Td (determine ) Tj ET Q q 0 0 0 rg BT 459.59 679.50 Td (whether ) Tj ET Q q 0 0 0 rg BT 493.76 679.50 Td (an ) Tj ET Q q 0 0 0 rg BT 505.17 679.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 553.23 679.50 Td (exists ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 667.50 Td (at ) Tj ET Q q 0 0 0 rg BT 45.20 667.50 Td (its ) Tj ET Q q 0 0 0 rg BT 56.63 667.50 Td (lowest ) Tj ET Q q 0 0 0 rg BT 84.72 667.50 Td (level ) Tj ET Q q 0 0 0 rg BT 106.14 667.50 Td (of ) Tj ET Q q 0 0 0 rg BT 116.45 667.50 Td (identifiable ) Tj ET Q q 0 0 0 rg BT 163.97 667.50 Td (cash ) Tj ET Q q 0 0 0 rg BT 183.72 667.50 Td (flows. ) Tj ET Q q 0 0 0 rg BT 210.42 667.50 Td (If ) Tj ET Q q 0 0 0 rg BT 219.07 667.50 Td (an ) Tj ET Q q 0 0 0 rg BT 230.49 667.50 Td (asset ) Tj ET Q q 0 0 0 rg BT 251.91 667.50 Td (is ) Tj ET Q q 0 0 0 rg BT 260.56 667.50 Td (determined ) Tj ET Q q 0 0 0 rg BT 307.52 667.50 Td (to ) Tj ET Q q 0 0 0 rg BT 317.28 667.50 Td (be ) Tj ET Q q 0 0 0 rg BT 328.71 667.50 Td (impaired, ) Tj ET Q q 0 0 0 rg BT 368.73 667.50 Td (the ) Tj ET Q q 0 0 0 rg BT 382.93 667.50 Td (loss ) Tj ET Q q 0 0 0 rg BT 400.47 667.50 Td (is ) Tj ET Q q 0 0 0 rg BT 409.13 667.50 Td (measured ) Tj ET Q q 0 0 0 rg BT 449.42 667.50 Td (based ) Tj ET Q q 0 0 0 rg BT 474.17 667.50 Td (on ) Tj ET Q q 0 0 0 rg BT 486.16 667.50 Td (the ) Tj ET Q q 0 0 0 rg BT 500.36 667.50 Td (dif) Tj ET Q q 0 0 0 rg BT 511.28 667.50 Td (ference ) Tj ET Q q 0 0 0 rg BT 542.68 667.50 Td (between ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 655.50 Td (the ) Tj ET Q q 0 0 0 rg BT 50.86 655.50 Td (asset’) Tj ET Q q 0 0 0 rg BT 73.08 655.50 Td (s ) Tj ET Q q 0 0 0 rg BT 79.62 655.50 Td (fair ) Tj ET Q q 0 0 0 rg BT 96.15 655.50 Td (value ) Tj ET Q q 0 0 0 rg BT 120.45 655.50 Td (and ) Tj ET Q q 0 0 0 rg BT 137.54 655.50 Td (its ) Tj ET Q q 0 0 0 rg BT 149.63 655.50 Td (carrying ) Tj ET Q q 0 0 0 rg BT 185.60 655.50 Td (value. ) Tj ET Q q 0 0 0 rg BT 212.40 655.50 Td (Expectations ) Tj ET Q q 0 0 0 rg BT 266.70 655.50 Td (of ) Tj ET Q q 0 0 0 rg BT 277.67 655.50 Td (future ) Tj ET Q q 0 0 0 rg BT 304.20 655.50 Td (cash ) Tj ET Q q 0 0 0 rg BT 324.62 655.50 Td (flows ) Tj ET Q q 0 0 0 rg BT 349.49 655.50 Td (are ) Tj ET Q q 0 0 0 rg BT 364.34 655.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 395.31 655.50 Td (to ) Tj ET Q q 0 0 0 rg BT 405.74 655.50 Td (change ) Tj ET Q q 0 0 0 rg BT 436.70 655.50 Td (based ) Tj ET Q q 0 0 0 rg BT 462.12 655.50 Td (upon ) Tj ET Q q 0 0 0 rg BT 484.77 655.50 Td (the ) Tj ET Q q 0 0 0 rg BT 499.63 655.50 Td (near ) Tj ET Q q 0 0 0 rg BT 519.49 655.50 Td (and ) Tj ET Q q 0 0 0 rg BT 536.57 655.50 Td (long-term ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 643.50 Td (production ) Tj ET Q q 0 0 0 rg BT 80.90 643.50 Td (volumes ) Tj ET Q q 0 0 0 rg BT 116.35 643.50 Td (and ) Tj ET Q q 0 0 0 rg BT 132.36 643.50 Td (mar) Tj ET Q q 0 0 0 rg BT 147.73 643.50 Td (gins ) Tj ET Q q 0 0 0 rg BT 165.97 643.50 Td (generated ) Tj ET Q q 0 0 0 rg BT 206.40 643.50 Td (by ) Tj ET Q q 0 0 0 rg BT 217.97 643.50 Td (the ) Tj ET Q q 0 0 0 rg BT 231.75 643.50 Td (asset ) Tj ET Q q 0 0 0 rg BT 252.76 643.50 Td (as ) Tj ET Q q 0 0 0 rg BT 262.66 643.50 Td (well ) Tj ET Q q 0 0 0 rg BT 281.45 643.50 Td (as ) Tj ET Q q 0 0 0 rg BT 291.35 643.50 Td (any ) Tj ET Q q 0 0 0 rg BT 307.36 643.50 Td (potential ) Tj ET Q q 0 0 0 rg BT 343.92 643.50 Td (alternative ) Tj ET Q q 0 0 0 rg BT 387.68 643.50 Td (future ) Tj ET Q q 0 0 0 rg BT 413.13 643.50 Td (use. ) Tj ET Q q 0 0 0 rg BT 430.42 643.50 Td (The ) Tj ET Q q 0 0 0 rg BT 447.53 643.50 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 491.32 643.50 Td (of ) Tj ET Q q 0 0 0 rg BT 501.22 643.50 Td (our ) Tj ET Q q 0 0 0 rg BT 516.12 643.50 Td (small ) Tj ET Q q 0 0 0 rg BT 539.35 643.50 Td (molecule ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 631.50 Td (active ) Tj ET Q q 0 0 0 rg BT 62.08 631.50 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 125.36 631.50 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 168.11 631.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 228.63 631.50 Td (operations ) Tj ET Q q 0 0 0 rg BT 272.49 631.50 Td (in ) Tj ET Q q 0 0 0 rg BT 282.47 631.50 Td (Swords, ) Tj ET Q q 0 0 0 rg BT 317.19 631.50 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 347.71 631.50 Td (and ) Tj ET Q q 0 0 0 rg BT 364.35 631.50 Td (sale ) Tj ET Q q 0 0 0 rg BT 382.11 631.50 Td (of ) Tj ET Q q 0 0 0 rg BT 392.65 631.50 Td (our ) Tj ET Q q 0 0 0 rg BT 408.18 631.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 432.06 631.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 462.59 631.50 Td (in ) Tj ET Q q 0 0 0 rg BT 472.41 631.50 Td (W) Tj ET Q q 0 0 0 rg BT 481.05 631.50 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 525.19 631.50 Td (Connecticut, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 619.50 Td (resulted ) Tj ET Q q 0 0 0 rg BT 69.96 619.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 80.05 619.50 Td ($146 ) Tj ET Q q 0 0 0 rg BT 102.36 619.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 131.25 619.50 Td ( ) Tj ET Q q 0 0 0 rg BT 133.56 619.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 150.31 619.50 Td ($79 ) Tj ET Q q 0 0 0 rg BT 167.62 619.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 196.51 619.50 Td ( ) Tj ET Q q 0 0 0 rg BT 198.82 619.50 Td (in ) Tj ET Q q 0 0 0 rg BT 208.91 619.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 257.32 619.50 Td (char) Tj ET Q q 0 0 0 rg BT 274.34 619.50 Td (ges, ) Tj ET Q q 0 0 0 rg BT 292.48 619.50 Td (respectively) Tj ET Q q 0 0 0 rg BT 340.15 619.50 Td (, ) Tj ET Q q 0 0 0 rg BT 344.96 619.50 Td (to ) Tj ET Q q 0 0 0 rg BT 355.04 619.50 Td (reduce ) Tj ET Q q 0 0 0 rg BT 384.00 619.50 Td (the ) Tj ET Q q 0 0 0 rg BT 398.52 619.50 Td (carrying ) Tj ET Q q 0 0 0 rg BT 434.15 619.50 Td (value ) Tj ET Q q 0 0 0 rg BT 458.11 619.50 Td (of ) Tj ET Q q 0 0 0 rg BT 468.75 619.50 Td (assets ) Tj ET Q q 0 0 0 rg BT 494.39 619.50 Td (held-for) Tj ET Q q 0 0 0 rg BT 526.40 619.50 Td (-sale ) Tj ET Q q 0 0 0 rg BT 547.59 619.50 Td (to ) Tj ET Q q 0 0 0 rg BT 557.67 619.50 Td (their ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 607.50 Td (fair ) Tj ET Q q 0 0 0 rg BT 52.78 607.50 Td (value ) Tj ET Q q 0 0 0 rg BT 77.34 607.50 Td (in ) Tj ET Q q 0 0 0 rg BT 88.03 607.50 Td (2017. ) Tj ET Q q 0 0 0 rg BT 112.79 607.50 Td (Accelerated ) Tj ET Q q 0 0 0 rg BT 163.44 607.50 Td (depreciation, ) Tj ET Q q 0 0 0 rg BT 218.26 607.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 267.26 607.50 Td (and ) Tj ET Q q 0 0 0 rg BT 284.61 607.50 Td (other ) Tj ET Q q 0 0 0 rg BT 308.06 607.50 Td (related ) Tj ET Q q 0 0 0 rg BT 338.17 607.50 Td (char) Tj ET Q q 0 0 0 rg BT 355.19 607.50 Td (ges ) Tj ET Q q 0 0 0 rg BT 371.43 607.50 Td (for ) Tj ET Q q 0 0 0 rg BT 385.99 607.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 416.10 607.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 477.32 607.50 Td (and ) Tj ET Q q 0 0 0 rg BT 494.66 607.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 519.24 607.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 556.57 607.50 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 595.50 Td ($533 ) Tj ET Q q 0 0 0 rg BT 57.55 595.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 86.44 595.50 Td ( ) Tj ET Q q 0 0 0 rg BT 87.98 595.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 97.31 595.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 117.31 595.50 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 121.35 595.50 Td ($104 ) Tj ET Q q 0 0 0 rg BT 142.90 595.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 171.79 595.50 Td ( ) Tj ET Q q 0 0 0 rg BT 173.33 595.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 182.66 595.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.66 595.50 Td ( ) Tj ET Q q 0 0 0 rg BT 204.20 595.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 220.19 595.50 Td ($1) Tj ET Q q 0 0 0 rg BT 229.82 595.50 Td (15 ) Tj ET Q q 0 0 0 rg BT 241.36 595.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 270.25 595.50 Td ( ) Tj ET Q q 0 0 0 rg BT 271.80 595.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 281.12 595.50 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.12 595.50 Td (. ) Tj ET Q q 0 0 0 rg BT 304.83 595.50 Td (Additional ) Tj ET Q q 0 0 0 rg BT 349.15 595.50 Td (char) Tj ET Q q 0 0 0 rg BT 366.17 595.50 Td (ges ) Tj ET Q q 0 0 0 rg BT 381.05 595.50 Td (will ) Tj ET Q q 0 0 0 rg BT 398.15 595.50 Td (continue ) Tj ET Q q 0 0 0 rg BT 434.13 595.50 Td (to ) Tj ET Q q 0 0 0 rg BT 443.45 595.50 Td (occur ) Tj ET Q q 0 0 0 rg BT 467.20 595.50 Td (as ) Tj ET Q q 0 0 0 rg BT 477.08 595.50 Td (a ) Tj ET Q q 0 0 0 rg BT 483.06 595.50 Td (result ) Tj ET Q q 0 0 0 rg BT 506.83 595.50 Td (of ) Tj ET Q q 0 0 0 rg BT 516.70 595.50 Td (the ) Tj ET Q q 0 0 0 rg BT 530.46 595.50 Td (Company’) Tj ET Q q 0 0 0 rg BT 572.13 595.50 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 583.50 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 89.59 583.50 Td (actions ) Tj ET Q q 0 0 0 rg BT 120.42 583.50 Td (announced ) Tj ET Q q 0 0 0 rg BT 166.23 583.50 Td (in ) Tj ET Q q 0 0 0 rg BT 176.51 583.50 Td (the ) Tj ET Q q 0 0 0 rg BT 191.23 583.50 Td (fourth ) Tj ET Q q 0 0 0 rg BT 218.17 583.50 Td (quarter ) Tj ET Q q 0 0 0 rg BT 248.98 583.50 Td (of ) Tj ET Q q 0 0 0 rg BT 259.81 583.50 Td (2016.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 560.5669921875 m 118.28515625 560.5669921875 l s q 0 0 0 rg BT 36.00 561.90 Td (Assets Held-for) Tj ET Q q 0 0 0 rg BT 97.74 561.90 Td (-Sale) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 537.90 Td (The ) Tj ET Q q 0 0 0 rg BT 54.22 537.90 Td (following ) Tj ET Q q 0 0 0 rg BT 95.79 537.90 Td (criteria ) Tj ET Q q 0 0 0 rg BT 126.77 537.90 Td (is ) Tj ET Q q 0 0 0 rg BT 136.12 537.90 Td (considered ) Tj ET Q q 0 0 0 rg BT 182.11 537.90 Td (before ) Tj ET Q q 0 0 0 rg BT 210.32 537.90 Td (concluding ) Tj ET Q q 0 0 0 rg BT 257.43 537.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 283.44 537.90 Td (are ) Tj ET Q q 0 0 0 rg BT 298.32 537.90 Td (classified ) Tj ET Q q 0 0 0 rg BT 338.76 537.90 Td (as ) Tj ET Q q 0 0 0 rg BT 349.76 537.90 Td (held-for) Tj ET Q q 0 0 0 rg BT 381.77 537.90 Td (-sale; ) Tj ET Q q 0 0 0 rg BT 406.10 537.90 Td (1\) ) Tj ET Q q 0 0 0 rg BT 417.11 537.90 Td (management’) Tj ET Q q 0 0 0 rg BT 470.98 537.90 Td (s ) Tj ET Q q 0 0 0 rg BT 477.54 537.90 Td (commitment ) Tj ET Q q 0 0 0 rg BT 530.77 537.90 Td (to ) Tj ET Q q 0 0 0 rg BT 541.22 537.90 Td (a ) Tj ET Q q 0 0 0 rg BT 548.33 537.90 Td (plan ) Tj ET Q q 0 0 0 rg BT 568.23 537.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 525.90 Td (sell, ) Tj ET Q q 0 0 0 rg BT 55.06 525.90 Td (2\) ) Tj ET Q q 0 0 0 rg BT 66.06 525.90 Td (availability ) Tj ET Q q 0 0 0 rg BT 113.71 525.90 Td (for ) Tj ET Q q 0 0 0 rg BT 128.04 525.90 Td (immediate ) Tj ET Q q 0 0 0 rg BT 172.92 525.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 191.14 525.90 Td (in ) Tj ET Q q 0 0 0 rg BT 201.58 525.90 Td (its ) Tj ET Q q 0 0 0 rg BT 213.70 525.90 Td (present ) Tj ET Q q 0 0 0 rg BT 245.25 525.90 Td (condition, ) Tj ET Q q 0 0 0 rg BT 288.19 525.90 Td (3\) ) Tj ET Q q 0 0 0 rg BT 299.19 525.90 Td (initiation ) Tj ET Q q 0 0 0 rg BT 337.97 525.90 Td (of ) Tj ET Q q 0 0 0 rg BT 348.97 525.90 Td (an ) Tj ET Q q 0 0 0 rg BT 361.08 525.90 Td (active ) Tj ET Q q 0 0 0 rg BT 387.62 525.90 Td (program ) Tj ET Q q 0 0 0 rg BT 424.17 525.90 Td (to ) Tj ET Q q 0 0 0 rg BT 434.62 525.90 Td (identify ) Tj ET Q q 0 0 0 rg BT 468.39 525.90 Td (a ) Tj ET Q q 0 0 0 rg BT 475.50 525.90 Td (buyer) Tj ET Q q 0 0 0 rg BT 497.87 525.90 Td (, ) Tj ET Q q 0 0 0 rg BT 503.04 525.90 Td (4\) ) Tj ET Q q 0 0 0 rg BT 514.04 525.90 Td (probability ) Tj ET Q q 0 0 0 rg BT 560.59 525.90 Td (of ) Tj ET Q q 0 0 0 rg BT 571.59 525.90 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 513.90 Td (completed ) Tj ET Q q 0 0 0 rg BT 80.24 513.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 98.37 513.90 Td (within ) Tj ET Q q 0 0 0 rg BT 126.52 513.90 Td (one ) Tj ET Q q 0 0 0 rg BT 143.54 513.90 Td (year) Tj ET Q q 0 0 0 rg BT 160.35 513.90 Td (, ) Tj ET Q q 0 0 0 rg BT 165.44 513.90 Td (5\) ) Tj ET Q q 0 0 0 rg BT 176.36 513.90 Td (actively ) Tj ET Q q 0 0 0 rg BT 210.59 513.90 Td (marketed ) Tj ET Q q 0 0 0 rg BT 250.38 513.90 Td (for ) Tj ET Q q 0 0 0 rg BT 264.63 513.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 282.77 513.90 Td (at ) Tj ET Q q 0 0 0 rg BT 292.57 513.90 Td (a ) Tj ET Q q 0 0 0 rg BT 299.60 513.90 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 344.94 513.90 Td (price ) Tj ET Q q 0 0 0 rg BT 367.51 513.90 Td (in ) Tj ET Q q 0 0 0 rg BT 377.88 513.90 Td (relation ) Tj ET Q q 0 0 0 rg BT 411.01 513.90 Td (to ) Tj ET Q q 0 0 0 rg BT 421.38 513.90 Td (its ) Tj ET Q q 0 0 0 rg BT 433.41 513.90 Td (current ) Tj ET Q q 0 0 0 rg BT 464.32 513.90 Td (fair ) Tj ET Q q 0 0 0 rg BT 480.78 513.90 Td (value, ) Tj ET Q q 0 0 0 rg BT 507.52 513.90 Td (and ) Tj ET Q q 0 0 0 rg BT 524.55 513.90 Td (6\) ) Tj ET Q q 0 0 0 rg BT 535.47 513.90 Td (likelihood ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 501.90 Td (of ) Tj ET Q q 0 0 0 rg BT 46.62 501.90 Td (significant ) Tj ET Q q 0 0 0 rg BT 91.12 501.90 Td (changes ) Tj ET Q q 0 0 0 rg BT 125.62 501.90 Td (to ) Tj ET Q q 0 0 0 rg BT 135.68 501.90 Td (the ) Tj ET Q q 0 0 0 rg BT 150.19 501.90 Td (plan ) Tj ET Q q 0 0 0 rg BT 169.70 501.90 Td (will ) Tj ET Q q 0 0 0 rg BT 187.54 501.90 Td (be ) Tj ET Q q 0 0 0 rg BT 199.27 501.90 Td (made ) Tj ET Q q 0 0 0 rg BT 223.21 501.90 Td (or ) Tj ET Q q 0 0 0 rg BT 233.83 501.90 Td (that ) Tj ET Q q 0 0 0 rg BT 251.12 501.90 Td (the ) Tj ET Q q 0 0 0 rg BT 265.62 501.90 Td (plan ) Tj ET Q q 0 0 0 rg BT 285.13 501.90 Td (will ) Tj ET Q q 0 0 0 rg BT 302.97 501.90 Td (be ) Tj ET Q q 0 0 0 rg BT 314.70 501.90 Td (withdrawn. ) Tj ET Q q 0 0 0 rg BT 362.26 501.90 Td (If ) Tj ET Q q 0 0 0 rg BT 371.21 501.90 Td (all ) Tj ET Q q 0 0 0 rg BT 383.49 501.90 Td (of ) Tj ET Q q 0 0 0 rg BT 394.11 501.90 Td (the ) Tj ET Q q 0 0 0 rg BT 408.62 501.90 Td (criteria ) Tj ET Q q 0 0 0 rg BT 439.22 501.90 Td (is ) Tj ET Q q 0 0 0 rg BT 448.18 501.90 Td (met ) Tj ET Q q 0 0 0 rg BT 465.46 501.90 Td (as ) Tj ET Q q 0 0 0 rg BT 476.08 501.90 Td (of ) Tj ET Q q 0 0 0 rg BT 486.70 501.90 Td (the ) Tj ET Q q 0 0 0 rg BT 501.20 501.90 Td (balance ) Tj ET Q q 0 0 0 rg BT 534.03 501.90 Td (sheet ) Tj ET Q q 0 0 0 rg BT 556.86 501.90 Td (date, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 489.90 Td (the ) Tj ET Q q 0 0 0 rg BT 50.76 489.90 Td (net ) Tj ET Q q 0 0 0 rg BT 65.51 489.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 91.39 489.90 Td (are ) Tj ET Q q 0 0 0 rg BT 106.13 489.90 Td (presented ) Tj ET Q q 0 0 0 rg BT 146.99 489.90 Td (separately ) Tj ET Q q 0 0 0 rg BT 190.06 489.90 Td (in ) Tj ET Q q 0 0 0 rg BT 200.38 489.90 Td (the ) Tj ET Q q 0 0 0 rg BT 215.14 489.90 Td (balance ) Tj ET Q q 0 0 0 rg BT 248.21 489.90 Td (sheet ) Tj ET Q q 0 0 0 rg BT 271.30 489.90 Td (as ) Tj ET Q q 0 0 0 rg BT 282.17 489.90 Td (held-for) Tj ET Q q 0 0 0 rg BT 314.18 489.90 Td (-sale ) Tj ET Q q 0 0 0 rg BT 335.59 489.90 Td (at ) Tj ET Q q 0 0 0 rg BT 345.35 489.90 Td (the ) Tj ET Q q 0 0 0 rg BT 360.11 489.90 Td (lower ) Tj ET Q q 0 0 0 rg BT 385.42 489.90 Td (of ) Tj ET Q q 0 0 0 rg BT 396.29 489.90 Td (its ) Tj ET Q q 0 0 0 rg BT 408.28 489.90 Td (carrying ) Tj ET Q q 0 0 0 rg BT 444.13 489.90 Td (amount ) Tj ET Q q 0 0 0 rg BT 476.67 489.90 Td (or ) Tj ET Q q 0 0 0 rg BT 487.54 489.90 Td (fair ) Tj ET Q q 0 0 0 rg BT 503.96 489.90 Td (value ) Tj ET Q q 0 0 0 rg BT 528.15 489.90 Td (less ) Tj ET Q q 0 0 0 rg BT 545.69 489.90 Td (costs ) Tj ET Q q 0 0 0 rg BT 568.23 489.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 477.90 Td (sell ) Tj ET Q q 0 0 0 rg BT 52.49 477.90 Td (and ) Tj ET Q q 0 0 0 rg BT 69.53 477.90 Td (is ) Tj ET Q q 0 0 0 rg BT 78.80 477.90 Td (no ) Tj ET Q q 0 0 0 rg BT 91.41 477.90 Td (longer ) Tj ET Q q 0 0 0 rg BT 119.55 477.90 Td (depreciated ) Tj ET Q q 0 0 0 rg BT 168.24 477.90 Td (or ) Tj ET Q q 0 0 0 rg BT 179.17 477.90 Td (amortized ) Tj ET Q q 0 0 0 rg BT 221.75 477.90 Td (while ) Tj ET Q q 0 0 0 rg BT 246.57 477.90 Td (classified ) Tj ET Q q 0 0 0 rg BT 286.94 477.90 Td (as ) Tj ET Q q 0 0 0 rg BT 297.87 477.90 Td (held-for) Tj ET Q q 0 0 0 rg BT 329.88 477.90 Td (-sale. ) Tj ET Q q 0 0 0 rg BT 353.86 477.90 Td (For ) Tj ET Q q 0 0 0 rg BT 370.35 477.90 Td (example, ) Tj ET Q q 0 0 0 rg BT 409.33 477.90 Td (in ) Tj ET Q q 0 0 0 rg BT 419.71 477.90 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 463.96 477.90 Td (the ) Tj ET Q q 0 0 0 rg BT 478.78 477.90 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 527.48 477.90 Td (of ) Tj ET Q q 0 0 0 rg BT 538.42 477.90 Td (our ) Tj ET Q q 0 0 0 rg BT 554.35 477.90 Td (small ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 465.90 Td (molecule ) Tj ET Q q 0 0 0 rg BT 75.04 465.90 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 135.75 465.90 Td (operations ) Tj ET Q q 0 0 0 rg BT 179.80 465.90 Td (in ) Tj ET Q q 0 0 0 rg BT 189.97 465.90 Td (Swords, ) Tj ET Q q 0 0 0 rg BT 224.87 465.90 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 255.58 465.90 Td (and ) Tj ET Q q 0 0 0 rg BT 272.41 465.90 Td (our ) Tj ET Q q 0 0 0 rg BT 288.14 465.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 306.08 465.90 Td (of ) Tj ET Q q 0 0 0 rg BT 316.80 465.90 Td (our ) Tj ET Q q 0 0 0 rg BT 332.52 465.90 Td (R&D ) Tj ET Q q 0 0 0 rg BT 356.59 465.90 Td (facility ) Tj ET Q q 0 0 0 rg BT 387.30 465.90 Td (in ) Tj ET Q q 0 0 0 rg BT 397.30 465.90 Td (W) Tj ET Q q 0 0 0 rg BT 405.94 465.90 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 450.27 465.90 Td (Connecticut, ) Tj ET Q q 0 0 0 rg BT 503.48 465.90 Td (we ) Tj ET Q q 0 0 0 rg BT 517.54 465.90 Td (concluded ) Tj ET Q q 0 0 0 rg BT 561.02 465.90 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.90 Td (all ) Tj ET Q q 0 0 0 rg BT 48.67 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 63.57 453.90 Td (necessary ) Tj ET Q q 0 0 0 rg BT 105.11 453.90 Td (held-for) Tj ET Q q 0 0 0 rg BT 137.12 453.90 Td (-sale ) Tj ET Q q 0 0 0 rg BT 158.68 453.90 Td (criteria ) Tj ET Q q 0 0 0 rg BT 189.66 453.90 Td (were ) Tj ET Q q 0 0 0 rg BT 211.77 453.90 Td (met ) Tj ET Q q 0 0 0 rg BT 229.44 453.90 Td (in ) Tj ET Q q 0 0 0 rg BT 239.90 453.90 Td (2017 ) Tj ET Q q 0 0 0 rg BT 262.58 453.90 Td (in ) Tj ET Q q 0 0 0 rg BT 273.04 453.90 Td (a ) Tj ET Q q 0 0 0 rg BT 280.15 453.90 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 318.92 453.90 Td (period ) Tj ET Q q 0 0 0 rg BT 347.15 453.90 Td (prior ) Tj ET Q q 0 0 0 rg BT 369.27 453.90 Td (to ) Tj ET Q q 0 0 0 rg BT 379.72 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 394.62 453.90 Td (completed ) Tj ET Q q 0 0 0 rg BT 438.95 453.90 Td (sale. ) Tj ET Q q 0 0 0 rg BT 459.67 453.90 Td (In ) Tj ET Q q 0 0 0 rg BT 470.68 453.90 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 515.01 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 529.90 453.90 Td (divestitures ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.90 Td (of ) Tj ET Q q 0 0 0 rg BT 46.81 441.90 Td (the ) Tj ET Q q 0 0 0 rg BT 61.50 441.90 Td (investigational ) Tj ET Q q 0 0 0 rg BT 122.86 441.90 Td (HIV) Tj ET Q q 0 0 0 rg BT 140.45 441.90 Td ( ) Tj ET Q q 0 0 0 rg BT 142.93 441.90 Td (medicines ) Tj ET Q q 0 0 0 rg BT 185.95 441.90 Td (business, ) Tj ET Q q 0 0 0 rg BT 224.82 441.90 Td (the ) Tj ET Q q 0 0 0 rg BT 239.51 441.90 Td (businesses ) Tj ET Q q 0 0 0 rg BT 284.21 441.90 Td (comprising ) Tj ET Q q 0 0 0 rg BT 331.69 441.90 Td (the ) Tj ET Q q 0 0 0 rg BT 346.38 441.90 Td (alliances ) Tj ET Q q 0 0 0 rg BT 383.84 441.90 Td (with ) Tj ET Q q 0 0 0 rg BT 404.10 441.90 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 435.46 441.90 Td (and ) Tj ET Q q 0 0 0 rg BT 452.37 441.90 Td (Lilly) Tj ET Q q 0 0 0 rg BT 471.17 441.90 Td (, ) Tj ET Q q 0 0 0 rg BT 476.14 441.90 Td (we ) Tj ET Q q 0 0 0 rg BT 490.28 441.90 Td (concluded ) Tj ET Q q 0 0 0 rg BT 533.85 441.90 Td (that ) Tj ET Q q 0 0 0 rg BT 551.33 441.90 Td (all ) Tj ET Q q 0 0 0 rg BT 563.80 441.90 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 429.90 Td (necessary ) Tj ET Q q 0 0 0 rg BT 77.37 429.90 Td (held-for) Tj ET Q q 0 0 0 rg BT 109.37 429.90 Td (-sale ) Tj ET Q q 0 0 0 rg BT 130.75 429.90 Td (criteria ) Tj ET Q q 0 0 0 rg BT 161.56 429.90 Td (were ) Tj ET Q q 0 0 0 rg BT 183.49 429.90 Td (met ) Tj ET Q q 0 0 0 rg BT 200.99 429.90 Td (in ) Tj ET Q q 0 0 0 rg BT 211.26 429.90 Td (2015.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 405.90 Td (Income T) Tj ET Q q 0 0 0 rg BT 74.80 405.90 Td (axes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 381.90 Td (V) Tj ET Q q 0 0 0 rg BT 42.11 381.90 Td (aluation ) Tj ET Q q 0 0 0 rg BT 76.91 381.90 Td (allowances ) Tj ET Q q 0 0 0 rg BT 123.91 381.90 Td (are ) Tj ET Q q 0 0 0 rg BT 138.70 381.90 Td (recognized ) Tj ET Q q 0 0 0 rg BT 185.15 381.90 Td (to ) Tj ET Q q 0 0 0 rg BT 195.51 381.90 Td (reduce ) Tj ET Q q 0 0 0 rg BT 224.73 381.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 260.62 381.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 275.42 381.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 301.33 381.90 Td (when ) Tj ET Q q 0 0 0 rg BT 325.58 381.90 Td (it ) Tj ET Q q 0 0 0 rg BT 333.71 381.90 Td (is ) Tj ET Q q 0 0 0 rg BT 342.97 381.90 Td (more ) Tj ET Q q 0 0 0 rg BT 366.09 381.90 Td (likely ) Tj ET Q q 0 0 0 rg BT 391.45 381.90 Td (than ) Tj ET Q q 0 0 0 rg BT 411.25 381.90 Td (not ) Tj ET Q q 0 0 0 rg BT 426.61 381.90 Td (that ) Tj ET Q q 0 0 0 rg BT 444.19 381.90 Td (a ) Tj ET Q q 0 0 0 rg BT 451.21 381.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 466.01 381.90 Td (benefit ) Tj ET Q q 0 0 0 rg BT 496.35 381.90 Td (will ) Tj ET Q q 0 0 0 rg BT 514.49 381.90 Td (not ) Tj ET Q q 0 0 0 rg BT 529.85 381.90 Td (be ) Tj ET Q q 0 0 0 rg BT 541.87 381.90 Td (realized. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.90 Td (The ) Tj ET Q q 0 0 0 rg BT 54.30 369.90 Td (assessment ) Tj ET Q q 0 0 0 rg BT 101.50 369.90 Td (of ) Tj ET Q q 0 0 0 rg BT 112.58 369.90 Td (whether ) Tj ET Q q 0 0 0 rg BT 147.54 369.90 Td (or ) Tj ET Q q 0 0 0 rg BT 158.63 369.90 Td (not ) Tj ET Q q 0 0 0 rg BT 174.16 369.90 Td (a ) Tj ET Q q 0 0 0 rg BT 181.36 369.90 Td (valuation ) Tj ET Q q 0 0 0 rg BT 221.32 369.90 Td (allowance ) Tj ET Q q 0 0 0 rg BT 264.61 369.90 Td (is ) Tj ET Q q 0 0 0 rg BT 274.04 369.90 Td (required ) Tj ET Q q 0 0 0 rg BT 310.11 369.90 Td (often ) Tj ET Q q 0 0 0 rg BT 333.41 369.90 Td (requires ) Tj ET Q q 0 0 0 rg BT 368.37 369.90 Td (significant ) Tj ET Q q 0 0 0 rg BT 413.34 369.90 Td (judgment ) Tj ET Q q 0 0 0 rg BT 453.87 369.90 Td (including ) Tj ET Q q 0 0 0 rg BT 494.40 369.90 Td (long-range ) Tj ET Q q 0 0 0 rg BT 540.47 369.90 Td (forecasts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.90 Td (of ) Tj ET Q q 0 0 0 rg BT 47.34 357.90 Td (future ) Tj ET Q q 0 0 0 rg BT 74.23 357.90 Td (taxable ) Tj ET Q q 0 0 0 rg BT 106.12 357.90 Td (income ) Tj ET Q q 0 0 0 rg BT 138.56 357.90 Td (and ) Tj ET Q q 0 0 0 rg BT 156.01 357.90 Td (evaluation ) Tj ET Q q 0 0 0 rg BT 200.68 357.90 Td (of ) Tj ET Q q 0 0 0 rg BT 212.02 357.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 227.25 357.90 Td (planning ) Tj ET Q q 0 0 0 rg BT 265.26 357.90 Td (initiatives. ) Tj ET Q q 0 0 0 rg BT 309.54 357.90 Td (Adjustments ) Tj ET Q q 0 0 0 rg BT 363.11 357.90 Td (to ) Tj ET Q q 0 0 0 rg BT 373.90 357.90 Td (the ) Tj ET Q q 0 0 0 rg BT 389.13 357.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 425.45 357.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 440.68 357.90 Td (valuation ) Tj ET Q q 0 0 0 rg BT 480.91 357.90 Td (allowances ) Tj ET Q q 0 0 0 rg BT 528.34 357.90 Td (are ) Tj ET Q q 0 0 0 rg BT 543.56 357.90 Td (made ) Tj ET Q q 0 0 0 rg BT 568.23 357.90 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.90 Td (earnings ) Tj ET Q q 0 0 0 rg BT 71.99 345.90 Td (in ) Tj ET Q q 0 0 0 rg BT 81.89 345.90 Td (the ) Tj ET Q q 0 0 0 rg BT 96.22 345.90 Td (period ) Tj ET Q q 0 0 0 rg BT 123.89 345.90 Td (when ) Tj ET Q q 0 0 0 rg BT 147.66 345.90 Td (such ) Tj ET Q q 0 0 0 rg BT 168.11 345.90 Td (assessments ) Tj ET Q q 0 0 0 rg BT 218.56 345.90 Td (are ) Tj ET Q q 0 0 0 rg BT 232.88 345.90 Td (made. ) Tj ET Q q 0 0 0 rg BT 259.15 345.90 Td (Our ) Tj ET Q q 0 0 0 rg BT 276.82 345.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 312.24 345.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 326.58 345.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 352.02 345.90 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.57 345.90 Td ($2.3 ) Tj ET Q q 0 0 0 rg BT 393.19 345.90 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.30 345.90 Td ( ) Tj ET Q q 0 0 0 rg BT 421.42 345.90 Td (at ) Tj ET Q q 0 0 0 rg BT 430.75 345.90 Td (December ) Tj ET Q q 0 0 0 rg BT 473.95 345.90 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.57 345.90 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.57 345.90 Td ( ) Tj ET Q q 0 0 0 rg BT 510.68 345.90 Td (\(net ) Tj ET Q q 0 0 0 rg BT 528.35 345.90 Td (of ) Tj ET Q q 0 0 0 rg BT 538.79 345.90 Td (valuation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.90 Td (allowances ) Tj ET Q q 0 0 0 rg BT 82.92 333.90 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 93.75 333.90 Td ($2.8 ) Tj ET Q q 0 0 0 rg BT 113.75 333.90 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.87 333.90 Td (\) ) Tj ET Q q 0 0 0 rg BT 145.70 333.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 162.64 333.90 Td ($4.3 ) Tj ET Q q 0 0 0 rg BT 182.64 333.90 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 208.75 333.90 Td ( ) Tj ET Q q 0 0 0 rg BT 211.25 333.90 Td (at ) Tj ET Q q 0 0 0 rg BT 220.97 333.90 Td (December ) Tj ET Q q 0 0 0 rg BT 264.55 333.90 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 279.55 333.90 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 299.55 333.90 Td ( ) Tj ET Q q 0 0 0 rg BT 302.05 333.90 Td (\(net ) Tj ET Q q 0 0 0 rg BT 320.10 333.90 Td (of ) Tj ET Q q 0 0 0 rg BT 330.93 333.90 Td (valuation ) Tj ET Q q 0 0 0 rg BT 370.64 333.90 Td (allowances ) Tj ET Q q 0 0 0 rg BT 417.56 333.90 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.39 333.90 Td ($3.1 ) Tj ET Q q 0 0 0 rg BT 448.39 333.90 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.51 333.90 Td (\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.90 Td (The ) Tj ET Q q 0 0 0 rg BT 54.58 309.90 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 75.39 309.90 Td (Federal ) Tj ET Q q 0 0 0 rg BT 108.41 309.90 Td (net ) Tj ET Q q 0 0 0 rg BT 123.66 309.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 164.46 309.90 Td (loss ) Tj ET Q q 0 0 0 rg BT 183.05 309.90 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 242.16 309.90 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.62 309.90 Td ($317 ) Tj ET Q q 0 0 0 rg BT 287.66 309.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 316.55 309.90 Td ( ) Tj ET Q q 0 0 0 rg BT 319.58 309.90 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 329.83 309.90 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 388.94 309.90 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.94 309.90 Td (. ) Tj ET Q q 0 0 0 rg BT 414.26 309.90 Td (These ) Tj ET Q q 0 0 0 rg BT 441.17 309.90 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 500.28 309.90 Td (were ) Tj ET Q q 0 0 0 rg BT 522.74 309.90 Td (acquired ) Tj ET Q q 0 0 0 rg BT 560.19 309.90 Td (as ) Tj ET Q q 0 0 0 rg BT 571.56 309.90 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.90 Td (result ) Tj ET Q q 0 0 0 rg BT 61.78 297.90 Td (of ) Tj ET Q q 0 0 0 rg BT 73.67 297.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 104.43 297.90 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 155.76 297.90 Td (and ) Tj ET Q q 0 0 0 rg BT 173.76 297.90 Td (are ) Tj ET Q q 0 0 0 rg BT 189.53 297.90 Td (subject ) Tj ET Q q 0 0 0 rg BT 221.41 297.90 Td (to ) Tj ET Q q 0 0 0 rg BT 232.75 297.90 Td (limitations ) Tj ET Q q 0 0 0 rg BT 279.09 297.90 Td (under ) Tj ET Q q 0 0 0 rg BT 305.41 297.90 Td (Section 382 ) Tj ET Q q 0 0 0 rg BT 356.47 297.90 Td (of ) Tj ET Q q 0 0 0 rg BT 368.36 297.90 Td (the ) Tj ET Q q 0 0 0 rg BT 384.13 297.90 Td (Internal ) Tj ET Q q 0 0 0 rg BT 418.79 297.90 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 457.33 297.90 Td (Code. ) Tj ET Q q 0 0 0 rg BT 484.24 297.90 Td (The ) Tj ET Q q 0 0 0 rg BT 503.35 297.90 Td (net ) Tj ET Q q 0 0 0 rg BT 519.13 297.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 560.45 297.90 Td (loss ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.90 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 95.11 285.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 123.13 285.90 Td (in ) Tj ET Q q 0 0 0 rg BT 133.94 285.90 Td (varying ) Tj ET Q q 0 0 0 rg BT 167.51 285.90 Td (amounts ) Tj ET Q q 0 0 0 rg BT 204.43 285.90 Td (beginning ) Tj ET Q q 0 0 0 rg BT 247.46 285.90 Td (in ) Tj ET Q q 0 0 0 rg BT 258.27 285.90 Td (2022. ) Tj ET Q q 0 0 0 rg BT 283.58 285.90 Td (The ) Tj ET Q q 0 0 0 rg BT 302.16 285.90 Td (foreign ) Tj ET Q q 0 0 0 rg BT 334.07 285.90 Td (and ) Tj ET Q q 0 0 0 rg BT 351.54 285.90 Td (state ) Tj ET Q q 0 0 0 rg BT 372.89 285.90 Td (net ) Tj ET Q q 0 0 0 rg BT 388.14 285.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 428.94 285.90 Td (loss ) Tj ET Q q 0 0 0 rg BT 447.53 285.90 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 506.64 285.90 Td (expire ) Tj ET Q q 0 0 0 rg BT 534.66 285.90 Td (in ) Tj ET Q q 0 0 0 rg BT 545.47 285.90 Td (varying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.90 Td (amounts ) Tj ET Q q 0 0 0 rg BT 72.39 273.90 Td (beginning ) Tj ET Q q 0 0 0 rg BT 114.88 273.90 Td (in ) Tj ET Q q 0 0 0 rg BT 125.16 273.90 Td (2018 ) Tj ET Q q 0 0 0 rg BT 147.66 273.90 Td (\(certain ) Tj ET Q q 0 0 0 rg BT 180.69 273.90 Td (amounts ) Tj ET Q q 0 0 0 rg BT 217.08 273.90 Td (have ) Tj ET Q q 0 0 0 rg BT 238.46 273.90 Td (unlimited ) Tj ET Q q 0 0 0 rg BT 279.29 273.90 Td (lives\). ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 249.90 Td (As ) Tj ET Q q 0 0 0 rg BT 49.67 249.90 Td (discussed ) Tj ET Q q 0 0 0 rg BT 90.56 249.90 Td (more ) Tj ET Q q 0 0 0 rg BT 113.66 249.90 Td (fully ) Tj ET Q q 0 0 0 rg BT 135.11 249.90 Td (in ) Tj ET Q q 0 0 0 rg BT 145.44 249.90 Td (the ) Tj ET Q q 0 0 0 rg BT 160.22 249.90 Td (Results ) Tj ET Q q 0 0 0 rg BT 192.22 249.90 Td (of ) Tj ET Q q 0 0 0 rg BT 203.11 249.90 Td (Operations ) Tj ET Q q 0 0 0 rg BT 249.55 249.90 Td (section ) Tj ET Q q 0 0 0 rg BT 280.43 249.90 Td (of ) Tj ET Q q 0 0 0 rg BT 291.32 249.90 Td (this ) Tj ET Q q 0 0 0 rg BT 308.32 249.90 Td (MD&A, ) Tj ET Q q 0 0 0 rg BT 344.49 249.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 359.27 249.90 Td (char) Tj ET Q q 0 0 0 rg BT 376.29 249.90 Td (ges ) Tj ET Q q 0 0 0 rg BT 392.18 249.90 Td (attributed ) Tj ET Q q 0 0 0 rg BT 433.06 249.90 Td (to ) Tj ET Q q 0 0 0 rg BT 443.40 249.90 Td (the ) Tj ET Q q 0 0 0 rg BT 458.17 249.90 Td (one-time ) Tj ET Q q 0 0 0 rg BT 496.27 249.90 Td (deemed ) Tj ET Q q 0 0 0 rg BT 529.92 249.90 Td (repatriation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 237.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.92 237.90 Td (on ) Tj ET Q q 0 0 0 rg BT 63.62 237.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 93.53 237.90 Td (foreign ) Tj ET Q q 0 0 0 rg BT 125.11 237.90 Td (earnings ) Tj ET Q q 0 0 0 rg BT 161.69 237.90 Td (of ) Tj ET Q q 0 0 0 rg BT 172.72 237.90 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 192.92 237.90 Td (billion ) Tj ET Q q 0 0 0 rg BT 221.74 237.90 Td (were ) Tj ET Q q 0 0 0 rg BT 243.87 237.90 Td (recognized ) Tj ET Q q 0 0 0 rg BT 290.43 237.90 Td (in ) Tj ET Q q 0 0 0 rg BT 300.91 237.90 Td (the ) Tj ET Q q 0 0 0 rg BT 315.83 237.90 Td (fourth ) Tj ET Q q 0 0 0 rg BT 342.98 237.90 Td (quarter ) Tj ET Q q 0 0 0 rg BT 373.99 237.90 Td (of ) Tj ET Q q 0 0 0 rg BT 385.03 237.90 Td (2017. ) Tj ET Q q 0 0 0 rg BT 410.03 237.90 Td (The ) Tj ET Q q 0 0 0 rg BT 428.28 237.90 Td (accounting ) Tj ET Q q 0 0 0 rg BT 474.86 237.90 Td (for ) Tj ET Q q 0 0 0 rg BT 489.22 237.90 Td (this ) Tj ET Q q 0 0 0 rg BT 506.37 237.90 Td (income ) Tj ET Q q 0 0 0 rg BT 538.51 237.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 553.43 237.90 Td (ef) Tj ET Q q 0 0 0 rg BT 561.01 237.90 Td (fect ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 225.90 Td (of ) Tj ET Q q 0 0 0 rg BT 46.36 225.90 Td (the ) Tj ET Q q 0 0 0 rg BT 60.16 225.90 Td (Act ) Tj ET Q q 0 0 0 rg BT 76.63 225.90 Td (was ) Tj ET Q q 0 0 0 rg BT 94.21 225.90 Td (incomplete ) Tj ET Q q 0 0 0 rg BT 140.67 225.90 Td (as ) Tj ET Q q 0 0 0 rg BT 151.03 225.90 Td (of ) Tj ET Q q 0 0 0 rg BT 161.39 225.90 Td (the ) Tj ET Q q 0 0 0 rg BT 175.64 225.90 Td (issuance ) Tj ET Q q 0 0 0 rg BT 211.54 225.90 Td (date ) Tj ET Q q 0 0 0 rg BT 230.23 225.90 Td (of ) Tj ET Q q 0 0 0 rg BT 240.59 225.90 Td (the ) Tj ET Q q 0 0 0 rg BT 254.84 225.90 Td (financial ) Tj ET Q q 0 0 0 rg BT 291.85 225.90 Td (statements ) Tj ET Q q 0 0 0 rg BT 336.09 225.90 Td (as ) Tj ET Q q 0 0 0 rg BT 346.45 225.90 Td (we ) Tj ET Q q 0 0 0 rg BT 360.14 225.90 Td (did ) Tj ET Q q 0 0 0 rg BT 374.95 225.90 Td (not ) Tj ET Q q 0 0 0 rg BT 389.76 225.90 Td (have ) Tj ET Q q 0 0 0 rg BT 410.67 225.90 Td (all ) Tj ET Q q 0 0 0 rg BT 422.69 225.90 Td (of ) Tj ET Q q 0 0 0 rg BT 433.05 225.90 Td (the ) Tj ET Q q 0 0 0 rg BT 447.30 225.90 Td (necessary ) Tj ET Q q 0 0 0 rg BT 488.20 225.90 Td (information ) Tj ET Q q 0 0 0 rg BT 537.44 225.90 Td (available, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.90 Td (prepared ) Tj ET Q q 0 0 0 rg BT 73.03 213.90 Td (and ) Tj ET Q q 0 0 0 rg BT 89.52 213.90 Td (analyzed ) Tj ET Q q 0 0 0 rg BT 127.11 213.90 Td (to ) Tj ET Q q 0 0 0 rg BT 136.94 213.90 Td (complete ) Tj ET Q q 0 0 0 rg BT 175.65 213.90 Td (the ) Tj ET Q q 0 0 0 rg BT 189.92 213.90 Td (accounting. ) Tj ET Q q 0 0 0 rg BT 238.35 213.90 Td (However) Tj ET Q q 0 0 0 rg BT 274.60 213.90 Td (, ) Tj ET Q q 0 0 0 rg BT 279.15 213.90 Td (we ) Tj ET Q q 0 0 0 rg BT 292.87 213.90 Td (were ) Tj ET Q q 0 0 0 rg BT 314.35 213.90 Td (able ) Tj ET Q q 0 0 0 rg BT 333.06 213.90 Td (to ) Tj ET Q q 0 0 0 rg BT 342.89 213.90 Td (make ) Tj ET Q q 0 0 0 rg BT 366.60 213.90 Td (a ) Tj ET Q q 0 0 0 rg BT 373.10 213.90 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 417.90 213.90 Td (estimate ) Tj ET Q q 0 0 0 rg BT 453.28 213.90 Td (of ) Tj ET Q q 0 0 0 rg BT 463.66 213.90 Td (this ) Tj ET Q q 0 0 0 rg BT 480.17 213.90 Td (tax, ) Tj ET Q q 0 0 0 rg BT 496.94 213.90 Td (which ) Tj ET Q q 0 0 0 rg BT 523.43 213.90 Td (was ) Tj ET Q q 0 0 0 rg BT 541.04 213.90 Td (recorded ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.90 Td (as ) Tj ET Q q 0 0 0 rg BT 46.42 201.90 Td (a ) Tj ET Q q 0 0 0 rg BT 52.95 201.90 Td (provisional ) Tj ET Q q 0 0 0 rg BT 100.04 201.90 Td (amount. ) Tj ET Q q 0 0 0 rg BT 134.48 201.90 Td (The ) Tj ET Q q 0 0 0 rg BT 152.12 201.90 Td (provisional ) Tj ET Q q 0 0 0 rg BT 199.20 201.90 Td (amount ) Tj ET Q q 0 0 0 rg BT 231.29 201.90 Td (may ) Tj ET Q q 0 0 0 rg BT 250.60 201.90 Td (change ) Tj ET Q q 0 0 0 rg BT 281.01 201.90 Td (when ) Tj ET Q q 0 0 0 rg BT 304.76 201.90 Td (completed ) Tj ET Q q 0 0 0 rg BT 348.50 201.90 Td (in ) Tj ET Q q 0 0 0 rg BT 358.37 201.90 Td (2018 ) Tj ET Q q 0 0 0 rg BT 380.47 201.90 Td (upon ) Tj ET Q q 0 0 0 rg BT 402.56 201.90 Td (finalizing ) Tj ET Q q 0 0 0 rg BT 442.97 201.90 Td (the ) Tj ET Q q 0 0 0 rg BT 457.28 201.90 Td (2017 ) Tj ET Q q 0 0 0 rg BT 479.37 201.90 Td (taxable ) Tj ET Q q 0 0 0 rg BT 510.34 201.90 Td (income, ) Tj ET Q q 0 0 0 rg BT 544.36 201.90 Td (untaxed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.90 Td (post-1986 ) Tj ET Q q 0 0 0 rg BT 78.44 189.90 Td (foreign ) Tj ET Q q 0 0 0 rg BT 109.76 189.90 Td (earnings ) Tj ET Q q 0 0 0 rg BT 146.08 189.90 Td (and ) Tj ET Q q 0 0 0 rg BT 162.96 189.90 Td (profits ) Tj ET Q q 0 0 0 rg BT 191.52 189.90 Td (and ) Tj ET Q q 0 0 0 rg BT 208.40 189.90 Td (related ) Tj ET Q q 0 0 0 rg BT 238.04 189.90 Td (cash ) Tj ET Q q 0 0 0 rg BT 258.25 189.90 Td (and ) Tj ET Q q 0 0 0 rg BT 275.13 189.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 304.78 189.90 Td (eligible ) Tj ET Q q 0 0 0 rg BT 337.21 189.90 Td (assets ) Tj ET Q q 0 0 0 rg BT 362.99 189.90 Td (of ) Tj ET Q q 0 0 0 rg BT 373.76 189.90 Td (the ) Tj ET Q q 0 0 0 rg BT 388.42 189.90 Td (specified ) Tj ET Q q 0 0 0 rg BT 426.95 189.90 Td (foreign ) Tj ET Q q 0 0 0 rg BT 458.27 189.90 Td (corporations. ) Tj ET Q q 0 0 0 rg BT 513.03 189.90 Td (The ) Tj ET Q q 0 0 0 rg BT 531.02 189.90 Td (provisional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 177.90 Td (amounts ) Tj ET Q q 0 0 0 rg BT 72.39 177.90 Td (may ) Tj ET Q q 0 0 0 rg BT 92.10 177.90 Td (also ) Tj ET Q q 0 0 0 rg BT 110.71 177.90 Td (change ) Tj ET Q q 0 0 0 rg BT 141.53 177.90 Td (if ) Tj ET Q q 0 0 0 rg BT 150.14 177.90 Td (additional ) Tj ET Q q 0 0 0 rg BT 192.63 177.90 Td (interpretations ) Tj ET Q q 0 0 0 rg BT 252.88 177.90 Td (of ) Tj ET Q q 0 0 0 rg BT 263.71 177.90 Td (the ) Tj ET Q q 0 0 0 rg BT 278.43 177.90 Td (relevant ) Tj ET Q q 0 0 0 rg BT 313.13 177.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 327.85 177.90 Td (code ) Tj ET Q q 0 0 0 rg BT 349.23 177.90 Td (are ) Tj ET Q q 0 0 0 rg BT 363.93 177.90 Td (released.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 153.90 Td (Prior ) Tj ET Q q 0 0 0 rg BT 58.69 153.90 Td (to ) Tj ET Q q 0 0 0 rg BT 69.15 153.90 Td (the ) Tj ET Q q 0 0 0 rg BT 84.05 153.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 109.51 153.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 144.97 153.90 Td (split-of) Tj ET Q q 0 0 0 rg BT 173.68 153.90 Td (f ) Tj ET Q q 0 0 0 rg BT 179.70 153.90 Td (in ) Tj ET Q q 0 0 0 rg BT 190.16 153.90 Td (2009, ) Tj ET Q q 0 0 0 rg BT 215.35 153.90 Td (the ) Tj ET Q q 0 0 0 rg BT 230.25 153.90 Td (following ) Tj ET Q q 0 0 0 rg BT 271.82 153.90 Td (transactions ) Tj ET Q q 0 0 0 rg BT 322.27 153.90 Td (occurred: ) Tj ET Q q 0 0 0 rg BT 362.71 153.90 Td (\(i\) an ) Tj ET Q q 0 0 0 rg BT 386.77 153.90 Td (internal ) Tj ET Q q 0 0 0 rg BT 420.00 153.90 Td (spin-of) Tj ET Q q 0 0 0 rg BT 448.15 153.90 Td (f ) Tj ET Q q 0 0 0 rg BT 454.16 153.90 Td (of ) Tj ET Q q 0 0 0 rg BT 465.18 153.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 490.63 153.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 526.10 153.90 Td (shares ) Tj ET Q q 0 0 0 rg BT 553.78 153.90 Td (while ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 141.90 Td (still ) Tj ET Q q 0 0 0 rg BT 53.29 141.90 Td (owned ) Tj ET Q q 0 0 0 rg BT 82.23 141.90 Td (by ) Tj ET Q q 0 0 0 rg BT 94.52 141.90 Td (us; ) Tj ET Q q 0 0 0 rg BT 108.47 141.90 Td (\(ii\) conversion ) Tj ET Q q 0 0 0 rg BT 169.35 141.90 Td (of ) Tj ET Q q 0 0 0 rg BT 179.96 141.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 205.02 141.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 240.08 141.90 Td (Class ) Tj ET Q q 0 0 0 rg BT 264.04 141.90 Td (B ) Tj ET Q q 0 0 0 rg BT 272.99 141.90 Td (shares ) Tj ET Q q 0 0 0 rg BT 300.27 141.90 Td (to ) Tj ET Q q 0 0 0 rg BT 310.33 141.90 Td (Class ) Tj ET Q q 0 0 0 rg BT 333.95 141.90 Td (A) Tj ET Q q 0 0 0 rg BT 340.62 141.90 Td ( ) Tj ET Q q 0 0 0 rg BT 342.90 141.90 Td (shares; ) Tj ET Q q 0 0 0 rg BT 372.95 141.90 Td (and; ) Tj ET Q q 0 0 0 rg BT 392.46 141.90 Td (\(iii\) conversion ) Tj ET Q q 0 0 0 rg BT 456.11 141.90 Td (of ) Tj ET Q q 0 0 0 rg BT 466.73 141.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 491.78 141.90 Td (Johnson & ) Tj ET Q q 0 0 0 rg BT 537.12 141.90 Td (Company ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 129.90 Td (to ) Tj ET Q q 0 0 0 rg BT 46.29 129.90 Td (a ) Tj ET Q q 0 0 0 rg BT 53.24 129.90 Td (limited ) Tj ET Q q 0 0 0 rg BT 84.08 129.90 Td (liability ) Tj ET Q q 0 0 0 rg BT 117.70 129.90 Td (company) Tj ET Q q 0 0 0 rg BT 153.71 129.90 Td (. ) Tj ET Q q 0 0 0 rg BT 158.54 129.90 Td (These ) Tj ET Q q 0 0 0 rg BT 184.92 129.90 Td (transactions ) Tj ET Q q 0 0 0 rg BT 235.20 129.90 Td (as ) Tj ET Q q 0 0 0 rg BT 246.04 129.90 Td (well ) Tj ET Q q 0 0 0 rg BT 265.77 129.90 Td (as ) Tj ET Q q 0 0 0 rg BT 276.61 129.90 Td (the ) Tj ET Q q 0 0 0 rg BT 291.34 129.90 Td (split-of) Tj ET Q q 0 0 0 rg BT 320.04 129.90 Td (f ) Tj ET Q q 0 0 0 rg BT 325.88 129.90 Td (of ) Tj ET Q q 0 0 0 rg BT 336.73 129.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 362.01 129.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 397.30 129.90 Td (through ) Tj ET Q q 0 0 0 rg BT 430.92 129.90 Td (the ) Tj ET Q q 0 0 0 rg BT 445.65 129.90 Td (exchange ) Tj ET Q q 0 0 0 rg BT 485.91 129.90 Td (of) Tj ET Q q 0 0 0 rg BT 494.06 129.90 Td (fer ) Tj ET Q q 0 0 0 rg BT 507.67 129.90 Td (should ) Tj ET Q q 0 0 0 rg BT 536.85 129.90 Td (qualify ) Tj ET Q q 0 0 0 rg BT 567.69 129.90 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 117.90 Td (tax-exempt ) Tj ET Q q 0 0 0 rg BT 83.43 117.90 Td (transactions ) Tj ET Q q 0 0 0 rg BT 133.64 117.90 Td (under ) Tj ET Q q 0 0 0 rg BT 158.86 117.90 Td (the ) Tj ET Q q 0 0 0 rg BT 173.53 117.90 Td (Internal ) Tj ET Q q 0 0 0 rg BT 207.07 117.90 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 244.51 117.90 Td (Code ) Tj ET Q q 0 0 0 rg BT 268.07 117.90 Td (based ) Tj ET Q q 0 0 0 rg BT 293.29 117.90 Td (upon ) Tj ET Q q 0 0 0 rg BT 315.74 117.90 Td (a ) Tj ET Q q 0 0 0 rg BT 322.63 117.90 Td (private ) Tj ET Q q 0 0 0 rg BT 352.84 117.90 Td (letter ) Tj ET Q q 0 0 0 rg BT 375.83 117.90 Td (ruling ) Tj ET Q q 0 0 0 rg BT 402.17 117.90 Td (received ) Tj ET Q q 0 0 0 rg BT 438.48 117.90 Td (from ) Tj ET Q q 0 0 0 rg BT 460.37 117.90 Td (the ) Tj ET Q q 0 0 0 rg BT 475.04 117.90 Td (Internal ) Tj ET Q q 0 0 0 rg BT 508.58 117.90 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 546.02 117.90 Td (Service ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 105.90 Td (related ) Tj ET Q q 0 0 0 rg BT 65.70 105.90 Td (to ) Tj ET Q q 0 0 0 rg BT 75.98 105.90 Td (the ) Tj ET Q q 0 0 0 rg BT 90.70 105.90 Td (conversion ) Tj ET Q q 0 0 0 rg BT 137.07 105.90 Td (of ) Tj ET Q q 0 0 0 rg BT 147.90 105.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 173.17 105.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 208.46 105.90 Td (Class ) Tj ET Q q 0 0 0 rg BT 232.63 105.90 Td (B ) Tj ET Q q 0 0 0 rg BT 241.80 105.90 Td (shares ) Tj ET Q q 0 0 0 rg BT 269.29 105.90 Td (to ) Tj ET Q q 0 0 0 rg BT 279.56 105.90 Td (Class ) Tj ET Q q 0 0 0 rg BT 303.18 105.90 Td (A) Tj ET Q q 0 0 0 rg BT 309.85 105.90 Td ( ) Tj ET Q q 0 0 0 rg BT 312.35 105.90 Td (shares, ) Tj ET Q q 0 0 0 rg BT 342.34 105.90 Td (and ) Tj ET Q q 0 0 0 rg BT 359.28 105.90 Td (outside ) Tj ET Q q 0 0 0 rg BT 390.67 105.90 Td (legal ) Tj ET Q q 0 0 0 rg BT 412.60 105.90 Td (opinions. ) Tj ET Q endstream endobj 103 0 obj <> endobj 104 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Certain ) Tj ET Q q 0 0 0 rg BT 67.86 749.10 Td (assumptions, ) Tj ET Q q 0 0 0 rg BT 122.24 749.10 Td (representations ) Tj ET Q q 0 0 0 rg BT 185.21 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 202.08 749.10 Td (covenants ) Tj ET Q q 0 0 0 rg BT 244.49 749.10 Td (by ) Tj ET Q q 0 0 0 rg BT 256.92 749.10 Td (Mead ) Tj ET Q q 0 0 0 rg BT 282.12 749.10 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 317.33 749.10 Td (were ) Tj ET Q q 0 0 0 rg BT 339.19 749.10 Td (relied ) Tj ET Q q 0 0 0 rg BT 364.39 749.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 386.82 749.10 Td (regarding ) Tj ET Q q 0 0 0 rg BT 427.57 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 442.21 749.10 Td (future ) Tj ET Q q 0 0 0 rg BT 468.52 749.10 Td (conduct ) Tj ET Q q 0 0 0 rg BT 502.61 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 513.37 749.10 Td (its ) Tj ET Q q 0 0 0 rg BT 525.25 749.10 Td (business ) Tj ET Q q 0 0 0 rg BT 561.57 749.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 58.74 737.10 Td (matters ) Tj ET Q q 0 0 0 rg BT 90.36 737.10 Td (which ) Tj ET Q q 0 0 0 rg BT 116.99 737.10 Td (could ) Tj ET Q q 0 0 0 rg BT 141.39 737.10 Td (af) Tj ET Q q 0 0 0 rg BT 148.98 737.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 166.15 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 180.56 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 194.97 737.10 Td (treatment ) Tj ET Q q 0 0 0 rg BT 234.91 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 245.43 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 259.84 737.10 Td (exchange. ) Tj ET Q q 0 0 0 rg BT 302.28 737.10 Td (For ) Tj ET Q q 0 0 0 rg BT 318.36 737.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 356.92 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 371.33 737.10 Td (current ) Tj ET Q q 0 0 0 rg BT 401.83 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 416.24 737.10 Td (law ) Tj ET Q q 0 0 0 rg BT 432.87 737.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 472.26 737.10 Td (creates ) Tj ET Q q 0 0 0 rg BT 502.20 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 508.83 737.10 Td (presumption ) Tj ET Q q 0 0 0 rg BT 561.01 737.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.83 725.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 91.19 725.10 Td (would ) Tj ET Q q 0 0 0 rg BT 118.80 725.10 Td (be ) Tj ET Q q 0 0 0 rg BT 130.85 725.10 Td (taxable ) Tj ET Q q 0 0 0 rg BT 162.34 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 172.73 725.10 Td (us, ) Tj ET Q q 0 0 0 rg BT 186.73 725.10 Td (if ) Tj ET Q q 0 0 0 rg BT 195.45 725.10 Td (Mead ) Tj ET Q q 0 0 0 rg BT 220.83 725.10 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 256.22 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 267.17 725.10 Td (its ) Tj ET Q q 0 0 0 rg BT 279.23 725.10 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 332.37 725.10 Td (were ) Tj ET Q q 0 0 0 rg BT 354.41 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 364.80 725.10 Td (engage ) Tj ET Q q 0 0 0 rg BT 395.73 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 406.12 725.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 456.50 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 474.10 725.10 Td (result ) Tj ET Q q 0 0 0 rg BT 498.93 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 509.32 725.10 Td (a ) Tj ET Q q 0 0 0 rg BT 516.37 725.10 Td (50% ) Tj ET Q q 0 0 0 rg BT 537.31 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 548.25 725.10 Td (greater ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (change ) Tj ET Q q 0 0 0 rg BT 67.04 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 77.54 713.10 Td (its ) Tj ET Q q 0 0 0 rg BT 89.71 713.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 113.54 713.10 Td (ownership ) Tj ET Q q 0 0 0 rg BT 157.93 713.10 Td (during ) Tj ET Q q 0 0 0 rg BT 186.76 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 193.92 713.10 Td (four ) Tj ET Q q 0 0 0 rg BT 213.31 713.10 Td (year ) Tj ET Q q 0 0 0 rg BT 233.24 713.10 Td (period ) Tj ET Q q 0 0 0 rg BT 261.51 713.10 Td (beginning ) Tj ET Q q 0 0 0 rg BT 304.23 713.10 Td (two ) Tj ET Q q 0 0 0 rg BT 321.95 713.10 Td (years ) Tj ET Q q 0 0 0 rg BT 345.77 713.10 Td (before ) Tj ET Q q 0 0 0 rg BT 374.03 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 388.97 713.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 429.45 713.10 Td (of) Tj ET Q q 0 0 0 rg BT 437.60 713.10 Td (fer) Tj ET Q q 0 0 0 rg BT 448.30 713.10 Td (, ) Tj ET Q q 0 0 0 rg BT 453.52 713.10 Td (unless ) Tj ET Q q 0 0 0 rg BT 481.25 713.10 Td (it ) Tj ET Q q 0 0 0 rg BT 489.53 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 498.92 713.10 Td (established ) Tj ET Q q 0 0 0 rg BT 546.08 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 563.80 713.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 76.60 701.10 Td (of) Tj ET Q q 0 0 0 rg BT 84.75 701.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 98.69 701.10 Td (were ) Tj ET Q q 0 0 0 rg BT 120.96 701.10 Td (not ) Tj ET Q q 0 0 0 rg BT 136.59 701.10 Td (part ) Tj ET Q q 0 0 0 rg BT 154.98 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 166.15 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 173.43 701.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 193.50 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 204.67 701.10 Td (series ) Tj ET Q q 0 0 0 rg BT 230.28 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 241.46 701.10 Td (related ) Tj ET Q q 0 0 0 rg BT 271.50 701.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 322.11 701.10 Td (to ) Tj ET Q q 0 0 0 rg BT 332.73 701.10 Td (ef) Tj ET Q q 0 0 0 rg BT 340.32 701.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 358.15 701.10 Td (such ) Tj ET Q q 0 0 0 rg BT 379.33 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 386.61 701.10 Td (change ) Tj ET Q q 0 0 0 rg BT 417.77 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 428.39 701.10 Td (ownership. ) Tj ET Q q 0 0 0 rg BT 475.39 701.10 Td (If ) Tj ET Q q 0 0 0 rg BT 484.90 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 499.96 701.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 533.35 701.10 Td (spin-of) Tj ET Q q 0 0 0 rg BT 561.50 701.10 Td (f ) Tj ET Q q 0 0 0 rg BT 567.67 701.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 76.05 689.10 Td (of) Tj ET Q q 0 0 0 rg BT 84.20 689.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 97.60 689.10 Td (were ) Tj ET Q q 0 0 0 rg BT 119.33 689.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 166.61 689.10 Td (not ) Tj ET Q q 0 0 0 rg BT 181.69 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 191.77 689.10 Td (qualify ) Tj ET Q q 0 0 0 rg BT 222.39 689.10 Td (as ) Tj ET Q q 0 0 0 rg BT 233.02 689.10 Td (a ) Tj ET Q q 0 0 0 rg BT 239.76 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 254.28 689.10 Td (exempt ) Tj ET Q q 0 0 0 rg BT 286.01 689.10 Td (transaction, ) Tj ET Q q 0 0 0 rg BT 334.68 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 349.20 689.10 Td (transaction ) Tj ET Q q 0 0 0 rg BT 395.37 689.10 Td (could ) Tj ET Q q 0 0 0 rg BT 419.89 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 431.63 689.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 462.25 689.10 Td (to ) Tj ET Q q 0 0 0 rg BT 472.33 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 486.84 689.10 Td (as ) Tj ET Q q 0 0 0 rg BT 497.47 689.10 Td (if ) Tj ET Q q 0 0 0 rg BT 505.88 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 520.40 689.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 560.45 689.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (a ) Tj ET Q q 0 0 0 rg BT 42.94 677.10 Td (taxable ) Tj ET Q q 0 0 0 rg BT 74.31 677.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 92.36 677.10 Td (by ) Tj ET Q q 0 0 0 rg BT 104.86 677.10 Td (us ) Tj ET Q q 0 0 0 rg BT 116.25 677.10 Td (at ) Tj ET Q q 0 0 0 rg BT 125.97 677.10 Td (market ) Tj ET Q q 0 0 0 rg BT 156.23 677.10 Td (value.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 657.90 Td (In ) Tj ET Q q 0 0 0 rg BT 46.46 657.90 Td (addition, ) Tj ET Q q 0 0 0 rg BT 83.86 657.90 Td (a ) Tj ET Q q 0 0 0 rg BT 90.43 657.90 Td (negative ) Tj ET Q q 0 0 0 rg BT 126.43 657.90 Td (basis ) Tj ET Q q 0 0 0 rg BT 148.55 657.90 Td (or ) Tj ET Q q 0 0 0 rg BT 159.01 657.90 Td (excess ) Tj ET Q q 0 0 0 rg BT 187.24 657.90 Td (loss ) Tj ET Q q 0 0 0 rg BT 204.93 657.90 Td (account ) Tj ET Q q 0 0 0 rg BT 238.15 657.90 Td (\(ELA\) ) Tj ET Q q 0 0 0 rg BT 266.38 657.90 Td (existed ) Tj ET Q q 0 0 0 rg BT 296.83 657.90 Td (in ) Tj ET Q q 0 0 0 rg BT 306.74 657.90 Td (our ) Tj ET Q q 0 0 0 rg BT 322.19 657.90 Td (investment ) Tj ET Q q 0 0 0 rg BT 368.20 657.90 Td (in ) Tj ET Q q 0 0 0 rg BT 378.11 657.90 Td (stock ) Tj ET Q q 0 0 0 rg BT 401.35 657.90 Td (of ) Tj ET Q q 0 0 0 rg BT 411.80 657.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 436.70 657.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 471.61 657.90 Td (prior ) Tj ET Q q 0 0 0 rg BT 493.18 657.90 Td (to ) Tj ET Q q 0 0 0 rg BT 503.08 657.90 Td (these ) Tj ET Q q 0 0 0 rg BT 525.76 657.90 Td (transactions. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 645.90 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 645.90 Td (e ) Tj ET Q q 0 0 0 rg BT 51.34 645.90 Td (received ) Tj ET Q q 0 0 0 rg BT 87.47 645.90 Td (an ) Tj ET Q q 0 0 0 rg BT 99.18 645.90 Td (opinion ) Tj ET Q q 0 0 0 rg BT 132.00 645.90 Td (from ) Tj ET Q q 0 0 0 rg BT 153.71 645.90 Td (outside ) Tj ET Q q 0 0 0 rg BT 184.86 645.90 Td (legal ) Tj ET Q q 0 0 0 rg BT 206.56 645.90 Td (counsel ) Tj ET Q q 0 0 0 rg BT 239.38 645.90 Td (to ) Tj ET Q q 0 0 0 rg BT 249.42 645.90 Td (the ) Tj ET Q q 0 0 0 rg BT 263.91 645.90 Td (ef) Tj ET Q q 0 0 0 rg BT 271.49 645.90 Td (fect ) Tj ET Q q 0 0 0 rg BT 288.75 645.90 Td (that ) Tj ET Q q 0 0 0 rg BT 306.01 645.90 Td (it ) Tj ET Q q 0 0 0 rg BT 313.83 645.90 Td (is ) Tj ET Q q 0 0 0 rg BT 322.77 645.90 Td (more ) Tj ET Q q 0 0 0 rg BT 345.58 645.90 Td (likely ) Tj ET Q q 0 0 0 rg BT 370.62 645.90 Td (than ) Tj ET Q q 0 0 0 rg BT 390.11 645.90 Td (not ) Tj ET Q q 0 0 0 rg BT 405.15 645.90 Td (that ) Tj ET Q q 0 0 0 rg BT 422.41 645.90 Td (we ) Tj ET Q q 0 0 0 rg BT 436.34 645.90 Td (eliminated ) Tj ET Q q 0 0 0 rg BT 480.82 645.90 Td (the ) Tj ET Q q 0 0 0 rg BT 495.30 645.90 Td (ELA) Tj ET Q q 0 0 0 rg BT 514.19 645.90 Td ( ) Tj ET Q q 0 0 0 rg BT 516.45 645.90 Td (as ) Tj ET Q q 0 0 0 rg BT 527.05 645.90 Td (part ) Tj ET Q q 0 0 0 rg BT 544.86 645.90 Td (of ) Tj ET Q q 0 0 0 rg BT 555.46 645.90 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 633.90 Td (transactions ) Tj ET Q q 0 0 0 rg BT 86.39 633.90 Td (and ) Tj ET Q q 0 0 0 rg BT 103.46 633.90 Td (do ) Tj ET Q q 0 0 0 rg BT 116.09 633.90 Td (not ) Tj ET Q q 0 0 0 rg BT 131.50 633.90 Td (have ) Tj ET Q q 0 0 0 rg BT 153.01 633.90 Td (taxable ) Tj ET Q q 0 0 0 rg BT 184.51 633.90 Td (income ) Tj ET Q q 0 0 0 rg BT 216.58 633.90 Td (with ) Tj ET Q q 0 0 0 rg BT 236.99 633.90 Td (respect ) Tj ET Q q 0 0 0 rg BT 267.93 633.90 Td (to ) Tj ET Q q 0 0 0 rg BT 278.34 633.90 Td (the ) Tj ET Q q 0 0 0 rg BT 293.19 633.90 Td (ELA. ) Tj ET Q q 0 0 0 rg BT 317.57 633.90 Td (The ) Tj ET Q q 0 0 0 rg BT 335.75 633.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 350.60 633.90 Td (law ) Tj ET Q q 0 0 0 rg BT 367.67 633.90 Td (in ) Tj ET Q q 0 0 0 rg BT 378.07 633.90 Td (this ) Tj ET Q q 0 0 0 rg BT 395.15 633.90 Td (area ) Tj ET Q q 0 0 0 rg BT 414.43 633.90 Td (is ) Tj ET Q q 0 0 0 rg BT 423.73 633.90 Td (complex ) Tj ET Q q 0 0 0 rg BT 460.79 633.90 Td (and ) Tj ET Q q 0 0 0 rg BT 477.86 633.90 Td (it ) Tj ET Q q 0 0 0 rg BT 486.05 633.90 Td (is ) Tj ET Q q 0 0 0 rg BT 495.35 633.90 Td (possible ) Tj ET Q q 0 0 0 rg BT 530.76 633.90 Td (that ) Tj ET Q q 0 0 0 rg BT 548.39 633.90 Td (even ) Tj ET Q q 0 0 0 rg BT 569.90 633.90 Td (if ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.90 Td (the ) Tj ET Q q 0 0 0 rg BT 50.53 621.90 Td (internal ) Tj ET Q q 0 0 0 rg BT 83.38 621.90 Td (spin-of) Tj ET Q q 0 0 0 rg BT 111.53 621.90 Td (f ) Tj ET Q q 0 0 0 rg BT 117.17 621.90 Td (and ) Tj ET Q q 0 0 0 rg BT 133.92 621.90 Td (the ) Tj ET Q q 0 0 0 rg BT 148.45 621.90 Td (exchange ) Tj ET Q q 0 0 0 rg BT 188.51 621.90 Td (of) Tj ET Q q 0 0 0 rg BT 196.66 621.90 Td (fer ) Tj ET Q q 0 0 0 rg BT 210.07 621.90 Td (is ) Tj ET Q q 0 0 0 rg BT 219.05 621.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 233.58 621.90 Td (exempt ) Tj ET Q q 0 0 0 rg BT 265.33 621.90 Td (under ) Tj ET Q q 0 0 0 rg BT 290.41 621.90 Td (the ) Tj ET Q q 0 0 0 rg BT 304.93 621.90 Td (Internal ) Tj ET Q q 0 0 0 rg BT 338.34 621.90 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 375.63 621.90 Td (Code, ) Tj ET Q q 0 0 0 rg BT 401.55 621.90 Td (the ) Tj ET Q q 0 0 0 rg BT 416.08 621.90 Td (IRS ) Tj ET Q q 0 0 0 rg BT 433.95 621.90 Td (could ) Tj ET Q q 0 0 0 rg BT 458.48 621.90 Td (assert ) Tj ET Q q 0 0 0 rg BT 483.56 621.90 Td (that ) Tj ET Q q 0 0 0 rg BT 500.87 621.90 Td (we ) Tj ET Q q 0 0 0 rg BT 514.84 621.90 Td (have ) Tj ET Q q 0 0 0 rg BT 536.03 621.90 Td (additional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 609.90 Td (taxable ) Tj ET Q q 0 0 0 rg BT 67.75 609.90 Td (income ) Tj ET Q q 0 0 0 rg BT 100.05 609.90 Td (for ) Tj ET Q q 0 0 0 rg BT 114.59 609.90 Td (the ) Tj ET Q q 0 0 0 rg BT 129.68 609.90 Td (period ) Tj ET Q q 0 0 0 rg BT 158.10 609.90 Td (with ) Tj ET Q q 0 0 0 rg BT 178.75 609.90 Td (respect ) Tj ET Q q 0 0 0 rg BT 209.94 609.90 Td (to ) Tj ET Q q 0 0 0 rg BT 220.59 609.90 Td (the ) Tj ET Q q 0 0 0 rg BT 235.68 609.90 Td (ELA. ) Tj ET Q q 0 0 0 rg BT 260.28 609.90 Td (W) Tj ET Q q 0 0 0 rg BT 268.92 609.90 Td (e ) Tj ET Q q 0 0 0 rg BT 276.23 609.90 Td (could ) Tj ET Q q 0 0 0 rg BT 301.32 609.90 Td (be ) Tj ET Q q 0 0 0 rg BT 313.64 609.90 Td (exposed ) Tj ET Q q 0 0 0 rg BT 349.28 609.90 Td (to ) Tj ET Q q 0 0 0 rg BT 359.93 609.90 Td (additional ) Tj ET Q q 0 0 0 rg BT 402.79 609.90 Td (taxes ) Tj ET Q q 0 0 0 rg BT 426.21 609.90 Td (if ) Tj ET Q q 0 0 0 rg BT 435.20 609.90 Td (this ) Tj ET Q q 0 0 0 rg BT 452.52 609.90 Td (were ) Tj ET Q q 0 0 0 rg BT 474.82 609.90 Td (to ) Tj ET Q q 0 0 0 rg BT 485.47 609.90 Td (occur) Tj ET Q q 0 0 0 rg BT 507.13 609.90 Td (. ) Tj ET Q q 0 0 0 rg BT 512.50 609.90 Td (Based ) Tj ET Q q 0 0 0 rg BT 539.81 609.90 Td (upon ) Tj ET Q q 0 0 0 rg BT 562.69 609.90 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 597.90 Td (understanding ) Tj ET Q q 0 0 0 rg BT 94.26 597.90 Td (of ) Tj ET Q q 0 0 0 rg BT 104.20 597.90 Td (the ) Tj ET Q q 0 0 0 rg BT 118.02 597.90 Td (Internal ) Tj ET Q q 0 0 0 rg BT 150.72 597.90 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 187.31 597.90 Td (Code ) Tj ET Q q 0 0 0 rg BT 210.02 597.90 Td (and ) Tj ET Q q 0 0 0 rg BT 226.07 597.90 Td (opinion ) Tj ET Q q 0 0 0 rg BT 258.23 597.90 Td (from ) Tj ET Q q 0 0 0 rg BT 279.27 597.90 Td (outside ) Tj ET Q q 0 0 0 rg BT 309.76 597.90 Td (legal ) Tj ET Q q 0 0 0 rg BT 330.80 597.90 Td (counsel, ) Tj ET Q q 0 0 0 rg BT 365.46 597.90 Td (a ) Tj ET Q q 0 0 0 rg BT 371.50 597.90 Td (tax ) Tj ET Q q 0 0 0 rg BT 385.32 597.90 Td (reserve ) Tj ET Q q 0 0 0 rg BT 415.79 597.90 Td (of ) Tj ET Q q 0 0 0 rg BT 425.73 597.90 Td ($244 ) Tj ET Q q 0 0 0 rg BT 447.34 597.90 Td (million ) Tj ET Q q 0 0 0 rg BT 477.83 597.90 Td (was ) Tj ET Q q 0 0 0 rg BT 494.99 597.90 Td (established ) Tj ET Q q 0 0 0 rg BT 541.03 597.90 Td (reducing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 585.90 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 585.90 Td (gain ) Tj ET Q q 0 0 0 rg BT 70.43 585.90 Td (on ) Tj ET Q q 0 0 0 rg BT 82.93 585.90 Td (disposal ) Tj ET Q q 0 0 0 rg BT 118.21 585.90 Td (of ) Tj ET Q q 0 0 0 rg BT 129.04 585.90 Td (Mead ) Tj ET Q q 0 0 0 rg BT 154.31 585.90 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 189.59 585.90 Td (included ) Tj ET Q q 0 0 0 rg BT 226.53 585.90 Td (in ) Tj ET Q q 0 0 0 rg BT 236.81 585.90 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 290.41 585.90 Td (operations ) Tj ET Q q 0 0 0 rg BT 334.56 585.90 Td (in ) Tj ET Q q 0 0 0 rg BT 344.84 585.90 Td (2009.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 566.70 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 566.70 Td (e ) Tj ET Q q 0 0 0 rg BT 51.39 566.70 Td (agreed ) Tj ET Q q 0 0 0 rg BT 80.34 566.70 Td (to ) Tj ET Q q 0 0 0 rg BT 90.43 566.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 119.94 566.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 134.47 566.70 Td (related ) Tj ET Q q 0 0 0 rg BT 163.98 566.70 Td (indemnities ) Tj ET Q q 0 0 0 rg BT 212.95 566.70 Td (with ) Tj ET Q q 0 0 0 rg BT 233.04 566.70 Td (Mead ) Tj ET Q q 0 0 0 rg BT 258.11 566.70 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 293.21 566.70 Td (as ) Tj ET Q q 0 0 0 rg BT 303.85 566.70 Td (set ) Tj ET Q q 0 0 0 rg BT 317.26 566.70 Td (forth ) Tj ET Q q 0 0 0 rg BT 339.01 566.70 Td (in ) Tj ET Q q 0 0 0 rg BT 349.10 566.70 Td (the ) Tj ET Q q 0 0 0 rg BT 363.63 566.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 378.15 566.70 Td (sharing ) Tj ET Q q 0 0 0 rg BT 409.90 566.70 Td (agreement, ) Tj ET Q q 0 0 0 rg BT 456.35 566.70 Td (including ) Tj ET Q q 0 0 0 rg BT 496.43 566.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 525.95 566.70 Td (taxes ) Tj ET Q q 0 0 0 rg BT 548.80 566.70 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 554.70 Td (to ) Tj ET Q q 0 0 0 rg BT 46.71 554.70 Td (its ) Tj ET Q q 0 0 0 rg BT 59.09 554.70 Td (business ) Tj ET Q q 0 0 0 rg BT 95.92 554.70 Td (prior ) Tj ET Q q 0 0 0 rg BT 118.29 554.70 Td (to ) Tj ET Q q 0 0 0 rg BT 129.00 554.70 Td (the ) Tj ET Q q 0 0 0 rg BT 144.15 554.70 Td (completion ) Tj ET Q q 0 0 0 rg BT 192.08 554.70 Td (of ) Tj ET Q q 0 0 0 rg BT 203.34 554.70 Td (the ) Tj ET Q q 0 0 0 rg BT 218.49 554.70 Td (IPO ) Tj ET Q q 0 0 0 rg BT 237.54 554.70 Td (and ) Tj ET Q q 0 0 0 rg BT 254.91 554.70 Td (created ) Tj ET Q q 0 0 0 rg BT 286.71 554.70 Td (as ) Tj ET Q q 0 0 0 rg BT 297.97 554.70 Td (part ) Tj ET Q q 0 0 0 rg BT 316.45 554.70 Td (of ) Tj ET Q q 0 0 0 rg BT 327.71 554.70 Td (the ) Tj ET Q q 0 0 0 rg BT 342.86 554.70 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 396.89 554.70 Td (to ) Tj ET Q q 0 0 0 rg BT 407.60 554.70 Td (facilitate ) Tj ET Q q 0 0 0 rg BT 445.51 554.70 Td (the ) Tj ET Q q 0 0 0 rg BT 460.66 554.70 Td (IPO. ) Tj ET Q q 0 0 0 rg BT 482.21 554.70 Td (Mead ) Tj ET Q q 0 0 0 rg BT 507.91 554.70 Td (Johnson ) Tj ET Q q 0 0 0 rg BT 543.63 554.70 Td (has ) Tj ET Q q 0 0 0 rg BT 559.89 554.70 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 542.70 Td (agreed ) Tj ET Q q 0 0 0 rg BT 65.53 542.70 Td (to ) Tj ET Q q 0 0 0 rg BT 76.19 542.70 Td (indemnify ) Tj ET Q q 0 0 0 rg BT 120.17 542.70 Td (us ) Tj ET Q q 0 0 0 rg BT 131.94 542.70 Td (for ) Tj ET Q q 0 0 0 rg BT 146.48 542.70 Td (potential ) Tj ET Q q 0 0 0 rg BT 184.35 542.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 199.45 542.70 Td (ef) Tj ET Q q 0 0 0 rg BT 207.04 542.70 Td (fects ) Tj ET Q q 0 0 0 rg BT 228.80 542.70 Td (resulting ) Tj ET Q q 0 0 0 rg BT 266.67 542.70 Td (from ) Tj ET Q q 0 0 0 rg BT 288.99 542.70 Td (the ) Tj ET Q q 0 0 0 rg BT 304.09 542.70 Td (breach ) Tj ET Q q 0 0 0 rg BT 333.62 542.70 Td (of ) Tj ET Q q 0 0 0 rg BT 344.83 542.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 374.91 542.70 Td (representations ) Tj ET Q q 0 0 0 rg BT 438.32 542.70 Td (discussed ) Tj ET Q q 0 0 0 rg BT 479.54 542.70 Td (above ) Tj ET Q q 0 0 0 rg BT 506.29 542.70 Td (as ) Tj ET Q q 0 0 0 rg BT 517.50 542.70 Td (well ) Tj ET Q q 0 0 0 rg BT 537.60 542.70 Td (as ) Tj ET Q q 0 0 0 rg BT 548.81 542.70 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 530.70 Td (transactions ) Tj ET Q q 0 0 0 rg BT 86.26 530.70 Td (related ) Tj ET Q q 0 0 0 rg BT 115.97 530.70 Td (to ) Tj ET Q q 0 0 0 rg BT 126.24 530.70 Td (the ) Tj ET Q q 0 0 0 rg BT 140.96 530.70 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 187.34 530.70 Td (of ) Tj ET Q q 0 0 0 rg BT 198.17 530.70 Td (Mead ) Tj ET Q q 0 0 0 rg BT 223.44 530.70 Td (Johnson’) Tj ET Q q 0 0 0 rg BT 259.00 530.70 Td (s ) Tj ET Q q 0 0 0 rg BT 265.39 530.70 Td (stock ) Tj ET Q q 0 0 0 rg BT 289.00 530.70 Td (or ) Tj ET Q q 0 0 0 rg BT 299.83 530.70 Td (assets.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 511.50 Td (Liabilities ) Tj ET Q q 0 0 0 rg BT 79.18 511.50 Td (are ) Tj ET Q q 0 0 0 rg BT 94.01 511.50 Td (established ) Tj ET Q q 0 0 0 rg BT 141.08 511.50 Td (for ) Tj ET Q q 0 0 0 rg BT 155.37 511.50 Td (possible ) Tj ET Q q 0 0 0 rg BT 190.77 511.50 Td (assessments ) Tj ET Q q 0 0 0 rg BT 241.73 511.50 Td (by ) Tj ET Q q 0 0 0 rg BT 254.36 511.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 269.21 511.50 Td (authorities ) Tj ET Q q 0 0 0 rg BT 314.05 511.50 Td (resulting ) Tj ET Q q 0 0 0 rg BT 351.67 511.50 Td (from ) Tj ET Q q 0 0 0 rg BT 373.74 511.50 Td (known ) Tj ET Q q 0 0 0 rg BT 403.59 511.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 418.44 511.50 Td (exposures ) Tj ET Q q 0 0 0 rg BT 461.06 511.50 Td (including, ) Tj ET Q q 0 0 0 rg BT 503.96 511.50 Td (but ) Tj ET Q q 0 0 0 rg BT 519.37 511.50 Td (not ) Tj ET Q q 0 0 0 rg BT 534.78 511.50 Td (limited ) Tj ET Q q 0 0 0 rg BT 565.74 511.50 Td (to, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 499.50 Td (transfer ) Tj ET Q q 0 0 0 rg BT 70.08 499.50 Td (pricing ) Tj ET Q q 0 0 0 rg BT 101.94 499.50 Td (matters, ) Tj ET Q q 0 0 0 rg BT 137.42 499.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 153.17 499.50 Td (credits ) Tj ET Q q 0 0 0 rg BT 183.37 499.50 Td (and ) Tj ET Q q 0 0 0 rg BT 201.35 499.50 Td (deductibility ) Tj ET Q q 0 0 0 rg BT 255.43 499.50 Td (of ) Tj ET Q q 0 0 0 rg BT 267.30 499.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 298.05 499.50 Td (expenses. ) Tj ET Q q 0 0 0 rg BT 340.18 499.50 Td (Such ) Tj ET Q q 0 0 0 rg BT 363.72 499.50 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 404.48 499.50 Td (represent ) Tj ET Q q 0 0 0 rg BT 444.67 499.50 Td (a ) Tj ET Q q 0 0 0 rg BT 452.65 499.50 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 498.94 499.50 Td (provision ) Tj ET Q q 0 0 0 rg BT 540.26 499.50 Td (for ) Tj ET Q q 0 0 0 rg BT 555.46 499.50 Td (taxes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 487.50 Td (ultimately ) Tj ET Q q 0 0 0 rg BT 79.05 487.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 117.08 487.50 Td (to ) Tj ET Q q 0 0 0 rg BT 127.36 487.50 Td (be ) Tj ET Q q 0 0 0 rg BT 139.30 487.50 Td (paid ) Tj ET Q q 0 0 0 rg BT 159.01 487.50 Td (and ) Tj ET Q q 0 0 0 rg BT 175.95 487.50 Td (may ) Tj ET Q q 0 0 0 rg BT 195.67 487.50 Td (need ) Tj ET Q q 0 0 0 rg BT 217.04 487.50 Td (to ) Tj ET Q q 0 0 0 rg BT 227.32 487.50 Td (be ) Tj ET Q q 0 0 0 rg BT 239.26 487.50 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 275.09 487.50 Td (over ) Tj ET Q q 0 0 0 rg BT 295.36 487.50 Td (time ) Tj ET Q q 0 0 0 rg BT 315.63 487.50 Td (as ) Tj ET Q q 0 0 0 rg BT 326.46 487.50 Td (more ) Tj ET Q q 0 0 0 rg BT 349.51 487.50 Td (information ) Tj ET Q q 0 0 0 rg BT 399.22 487.50 Td (becomes ) Tj ET Q q 0 0 0 rg BT 436.70 487.50 Td (known.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 468.30 Td (For ) Tj ET Q q 0 0 0 rg BT 52.37 468.30 Td (discussions ) Tj ET Q q 0 0 0 rg BT 100.41 468.30 Td (on ) Tj ET Q q 0 0 0 rg BT 112.89 468.30 Td (income ) Tj ET Q q 0 0 0 rg BT 144.80 468.30 Td (taxes, ) Tj ET Q q 0 0 0 rg BT 170.32 468.30 Td (refer ) Tj ET Q q 0 0 0 rg BT 191.67 468.30 Td (to ) Tj ET Q q 0 0 0 rg BT 201.93 468.30 Td (“Item ) Tj ET Q q 0 0 0 rg BT 227.17 468.30 Td (8. ) Tj ET Q q 0 0 0 rg BT 237.15 468.30 Td (Financial ) Tj ET Q q 0 0 0 rg BT 276.83 468.30 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.63 468.30 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.63 468.30 Td (. ) Tj ET Q q 0 0 0 rg BT 362.06 468.30 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 411.20 468.30 Td (Policies—Income ) Tj ET Q q 0 0 0 rg BT 485.15 468.30 Td (T) Tj ET Q q 0 0 0 rg BT 490.56 468.30 Td (axes” ) Tj ET Q q 0 0 0 rg BT 515.24 468.30 Td (and ) Tj ET Q q 0 0 0 rg BT 532.16 468.30 Td (“—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 568.51 468.30 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.51 468.30 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 456.30 Td (Income ) Tj ET Q q 0 0 0 rg BT 68.30 456.30 Td (T) Tj ET Q q 0 0 0 rg BT 73.71 456.30 Td (axes.”) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 432.30 Td (Contingencies) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 410.70 Td (In ) Tj ET Q q 0 0 0 rg BT 46.82 410.70 Td (the ) Tj ET Q q 0 0 0 rg BT 61.54 410.70 Td (normal ) Tj ET Q q 0 0 0 rg BT 92.35 410.70 Td (course ) Tj ET Q q 0 0 0 rg BT 120.95 410.70 Td (of ) Tj ET Q q 0 0 0 rg BT 131.77 410.70 Td (business, ) Tj ET Q q 0 0 0 rg BT 170.66 410.70 Td (we ) Tj ET Q q 0 0 0 rg BT 184.81 410.70 Td (are ) Tj ET Q q 0 0 0 rg BT 199.51 410.70 Td (subject ) Tj ET Q q 0 0 0 rg BT 230.33 410.70 Td (to ) Tj ET Q q 0 0 0 rg BT 240.60 410.70 Td (contingencies, ) Tj ET Q q 0 0 0 rg BT 300.58 410.70 Td (such ) Tj ET Q q 0 0 0 rg BT 321.40 410.70 Td (as ) Tj ET Q q 0 0 0 rg BT 332.23 410.70 Td (legal ) Tj ET Q q 0 0 0 rg BT 354.16 410.70 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 404.96 410.70 Td (and ) Tj ET Q q 0 0 0 rg BT 421.90 410.70 Td (claims ) Tj ET Q q 0 0 0 rg BT 450.50 410.70 Td (arising ) Tj ET Q q 0 0 0 rg BT 480.21 410.70 Td (out ) Tj ET Q q 0 0 0 rg BT 495.48 410.70 Td (of ) Tj ET Q q 0 0 0 rg BT 506.30 410.70 Td (our ) Tj ET Q q 0 0 0 rg BT 522.13 410.70 Td (business, ) Tj ET Q q 0 0 0 rg BT 561.01 410.70 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 398.70 Td (cover ) Tj ET Q q 0 0 0 rg BT 61.31 398.70 Td (a ) Tj ET Q q 0 0 0 rg BT 68.85 398.70 Td (wide ) Tj ET Q q 0 0 0 rg BT 91.39 398.70 Td (range ) Tj ET Q q 0 0 0 rg BT 116.70 398.70 Td (of ) Tj ET Q q 0 0 0 rg BT 128.14 398.70 Td (matters, ) Tj ET Q q 0 0 0 rg BT 163.17 398.70 Td (including, ) Tj ET Q q 0 0 0 rg BT 206.55 398.70 Td (among ) Tj ET Q q 0 0 0 rg BT 236.87 398.70 Td (others, ) Tj ET Q q 0 0 0 rg BT 266.91 398.70 Td (government ) Tj ET Q q 0 0 0 rg BT 317.78 398.70 Td (investigations, ) Tj ET Q q 0 0 0 rg BT 378.93 398.70 Td (shareholder ) Tj ET Q q 0 0 0 rg BT 428.68 398.70 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 467.06 398.70 Td (product ) Tj ET Q q 0 0 0 rg BT 500.71 398.70 Td (and ) Tj ET Q q 0 0 0 rg BT 518.25 398.70 Td (environmental ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 386.70 Td (liability) Tj ET Q q 0 0 0 rg BT 66.46 386.70 Td (, ) Tj ET Q q 0 0 0 rg BT 72.16 386.70 Td (contractual ) Tj ET Q q 0 0 0 rg BT 119.79 386.70 Td (claims ) Tj ET Q q 0 0 0 rg BT 149.10 386.70 Td (and ) Tj ET Q q 0 0 0 rg BT 166.74 386.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 182.16 386.70 Td (matters. ) Tj ET Q q 0 0 0 rg BT 217.07 386.70 Td (W) Tj ET Q q 0 0 0 rg BT 225.70 386.70 Td (e ) Tj ET Q q 0 0 0 rg BT 233.35 386.70 Td (recognize ) Tj ET Q q 0 0 0 rg BT 275.41 386.70 Td (accruals ) Tj ET Q q 0 0 0 rg BT 311.37 386.70 Td (for ) Tj ET Q q 0 0 0 rg BT 326.24 386.70 Td (such ) Tj ET Q q 0 0 0 rg BT 347.77 386.70 Td (contingencies ) Tj ET Q q 0 0 0 rg BT 405.96 386.70 Td (when ) Tj ET Q q 0 0 0 rg BT 430.82 386.70 Td (it ) Tj ET Q q 0 0 0 rg BT 439.58 386.70 Td (is ) Tj ET Q q 0 0 0 rg BT 449.46 386.70 Td (probable ) Tj ET Q q 0 0 0 rg BT 487.65 386.70 Td (that ) Tj ET Q q 0 0 0 rg BT 505.85 386.70 Td (a ) Tj ET Q q 0 0 0 rg BT 513.49 386.70 Td (liability ) Tj ET Q q 0 0 0 rg BT 547.80 386.70 Td (will ) Tj ET Q q 0 0 0 rg BT 566.56 386.70 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 374.70 Td (incurred ) Tj ET Q q 0 0 0 rg BT 71.76 374.70 Td (and ) Tj ET Q q 0 0 0 rg BT 88.65 374.70 Td (the ) Tj ET Q q 0 0 0 rg BT 103.31 374.70 Td (amount ) Tj ET Q q 0 0 0 rg BT 135.76 374.70 Td (of ) Tj ET Q q 0 0 0 rg BT 146.53 374.70 Td (the ) Tj ET Q q 0 0 0 rg BT 161.20 374.70 Td (loss ) Tj ET Q q 0 0 0 rg BT 179.21 374.70 Td (can ) Tj ET Q q 0 0 0 rg BT 195.53 374.70 Td (be ) Tj ET Q q 0 0 0 rg BT 207.42 374.70 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 253.18 374.70 Td (estimated. ) Tj ET Q q 0 0 0 rg BT 296.27 374.70 Td (These ) Tj ET Q q 0 0 0 rg BT 322.60 374.70 Td (estimates ) Tj ET Q q 0 0 0 rg BT 362.26 374.70 Td (are ) Tj ET Q q 0 0 0 rg BT 376.91 374.70 Td (subject ) Tj ET Q q 0 0 0 rg BT 407.69 374.70 Td (to ) Tj ET Q q 0 0 0 rg BT 417.91 374.70 Td (uncertainties ) Tj ET Q q 0 0 0 rg BT 471.45 374.70 Td (that ) Tj ET Q q 0 0 0 rg BT 488.89 374.70 Td (are ) Tj ET Q q 0 0 0 rg BT 503.55 374.70 Td (dif) Tj ET Q q 0 0 0 rg BT 514.47 374.70 Td (ficult ) Tj ET Q q 0 0 0 rg BT 538.02 374.70 Td (to ) Tj ET Q q 0 0 0 rg BT 548.25 374.70 Td (predict ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 362.70 Td (and, ) Tj ET Q q 0 0 0 rg BT 55.44 362.70 Td (as ) Tj ET Q q 0 0 0 rg BT 66.27 362.70 Td (such, ) Tj ET Q q 0 0 0 rg BT 89.60 362.70 Td (actual ) Tj ET Q q 0 0 0 rg BT 115.97 362.70 Td (results ) Tj ET Q q 0 0 0 rg BT 144.58 362.70 Td (could ) Tj ET Q q 0 0 0 rg BT 169.30 362.70 Td (vary ) Tj ET Q q 0 0 0 rg BT 189.56 362.70 Td (from ) Tj ET Q q 0 0 0 rg BT 211.50 362.70 Td (these ) Tj ET Q q 0 0 0 rg BT 234.55 362.70 Td (estimates.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (For ) Tj ET Q q 0 0 0 rg BT 53.11 341.10 Td (discussions ) Tj ET Q q 0 0 0 rg BT 101.88 341.10 Td (on ) Tj ET Q q 0 0 0 rg BT 115.10 341.10 Td (contingencies, ) Tj ET Q q 0 0 0 rg BT 175.79 341.10 Td (refer ) Tj ET Q q 0 0 0 rg BT 197.87 341.10 Td (to ) Tj ET Q q 0 0 0 rg BT 208.87 341.10 Td (“Item ) Tj ET Q q 0 0 0 rg BT 234.84 341.10 Td (8. ) Tj ET Q q 0 0 0 rg BT 245.56 341.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 285.98 341.10 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.52 341.10 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.52 341.10 Td (. ) Tj ET Q q 0 0 0 rg BT 372.52 341.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 422.39 341.10 Td (Policies—Contingencies,” ) Tj ET Q q 0 0 0 rg BT 531.42 341.10 Td (“—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 568.51 341.10 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.51 341.10 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (Income ) Tj ET Q q 0 0 0 rg BT 68.30 329.10 Td (T) Tj ET Q q 0 0 0 rg BT 73.71 329.10 Td (axes” ) Tj ET Q q 0 0 0 rg BT 98.42 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 115.36 329.10 Td (“—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 151.74 329.10 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 161.74 329.10 Td (. ) Tj ET Q q 0 0 0 rg BT 166.74 329.10 Td (Legal ) Tj ET Q q 0 0 0 rg BT 192.00 329.10 Td (Proceedings ) Tj ET Q q 0 0 0 rg BT 243.38 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 260.32 329.10 Td (Contingencies.”) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (Pr) Tj ET Q q 0 0 0 rg BT 46.37 293.10 Td (oduct and Pipeline Developments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 276.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 53.42 276.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 76.96 276.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 116.60 276.10 Td (are ) Tj ET Q q 0 0 0 rg BT 130.68 276.10 Td (managed ) Tj ET Q q 0 0 0 rg BT 168.65 276.10 Td (on ) Tj ET Q q 0 0 0 rg BT 180.52 276.10 Td (a ) Tj ET Q q 0 0 0 rg BT 186.83 276.10 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 223.70 276.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 245.57 276.10 Td (from ) Tj ET Q q 0 0 0 rg BT 266.88 276.10 Td (early ) Tj ET Q q 0 0 0 rg BT 288.74 276.10 Td (discovery ) Tj ET Q q 0 0 0 rg BT 329.48 276.10 Td (through ) Tj ET Q q 0 0 0 rg BT 362.46 276.10 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 402.65 276.10 Td (development ) Tj ET Q q 0 0 0 rg BT 456.17 276.10 Td (and ) Tj ET Q q 0 0 0 rg BT 472.48 276.10 Td (include ) Tj ET Q q 0 0 0 rg BT 503.78 276.10 Td (a ) Tj ET Q q 0 0 0 rg BT 510.09 276.10 Td (balance ) Tj ET Q q 0 0 0 rg BT 542.50 276.10 Td (of ) Tj ET Q q 0 0 0 rg BT 552.70 276.10 Td (early-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 264.10 Td (stage ) Tj ET Q q 0 0 0 rg BT 58.00 264.10 Td (and ) Tj ET Q q 0 0 0 rg BT 73.90 264.10 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 113.66 264.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 152.88 264.10 Td (to ) Tj ET Q q 0 0 0 rg BT 162.12 264.10 Td (support ) Tj ET Q q 0 0 0 rg BT 193.57 264.10 Td (future ) Tj ET Q q 0 0 0 rg BT 218.91 264.10 Td (growth. ) Tj ET Q q 0 0 0 rg BT 251.19 264.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 268.20 264.10 Td (late ) Tj ET Q q 0 0 0 rg BT 284.09 264.10 Td (stage ) Tj ET Q q 0 0 0 rg BT 306.09 264.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 329.21 264.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 368.44 264.10 Td (in ) Tj ET Q q 0 0 0 rg BT 377.67 264.10 Td (Phase ) Tj ET Q q 0 0 0 rg BT 402.46 264.10 Td (III ) Tj ET Q q 0 0 0 rg BT 413.90 264.10 Td (development ) Tj ET Q q 0 0 0 rg BT 467.01 264.10 Td (include ) Tj ET Q q 0 0 0 rg BT 497.89 264.10 Td (both ) Tj ET Q q 0 0 0 rg BT 517.13 264.10 Td (investigational ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 252.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 83.90 252.10 Td (for ) Tj ET Q q 0 0 0 rg BT 97.36 252.10 Td (initial ) Tj ET Q q 0 0 0 rg BT 122.49 252.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 168.16 252.10 Td (and ) Tj ET Q q 0 0 0 rg BT 184.40 252.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 226.18 252.10 Td (indications ) Tj ET Q q 0 0 0 rg BT 271.86 252.10 Td (or ) Tj ET Q q 0 0 0 rg BT 281.99 252.10 Td (formulations ) Tj ET Q q 0 0 0 rg BT 334.89 252.10 Td (for ) Tj ET Q q 0 0 0 rg BT 348.34 252.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 387.34 252.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 426.08 252.10 Td (Spending ) Tj ET Q q 0 0 0 rg BT 465.65 252.10 Td (on ) Tj ET Q q 0 0 0 rg BT 477.45 252.10 Td (these ) Tj ET Q q 0 0 0 rg BT 499.79 252.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 539.35 252.10 Td (represent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 240.10 Td (approximately ) Tj ET Q q 0 0 0 rg BT 96.15 240.10 Td (30-45% ) Tj ET Q q 0 0 0 rg BT 130.20 240.10 Td (of ) Tj ET Q q 0 0 0 rg BT 140.92 240.10 Td (our ) Tj ET Q q 0 0 0 rg BT 156.65 240.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 185.69 240.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 209.75 240.10 Td (expenses ) Tj ET Q q 0 0 0 rg BT 248.24 240.10 Td (in ) Tj ET Q q 0 0 0 rg BT 258.41 240.10 Td (the ) Tj ET Q q 0 0 0 rg BT 273.02 240.10 Td (last ) Tj ET Q q 0 0 0 rg BT 289.30 240.10 Td (three ) Tj ET Q q 0 0 0 rg BT 311.68 240.10 Td (years. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 337.67 240.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.11 240.10 Td ( ) Tj ET Q q 0 0 0 rg BT 369.50 240.10 Td (was ) Tj ET Q q 0 0 0 rg BT 387.44 240.10 Td (the ) Tj ET Q q 0 0 0 rg BT 402.05 240.10 Td (only ) Tj ET Q q 0 0 0 rg BT 422.22 240.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 483.49 240.10 Td (compound ) Tj ET Q q 0 0 0 rg BT 528.10 240.10 Td (or ) Tj ET Q q 0 0 0 rg BT 538.82 240.10 Td (marketed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.10 Td (product ) Tj ET Q q 0 0 0 rg BT 69.85 228.10 Td (that ) Tj ET Q q 0 0 0 rg BT 88.14 228.10 Td (represented ) Tj ET Q q 0 0 0 rg BT 137.53 228.10 Td (greater ) Tj ET Q q 0 0 0 rg BT 168.58 228.10 Td (than ) Tj ET Q q 0 0 0 rg BT 189.10 228.10 Td (10% ) Tj ET Q q 0 0 0 rg BT 210.73 228.10 Td (of ) Tj ET Q q 0 0 0 rg BT 222.36 228.10 Td (our ) Tj ET Q q 0 0 0 rg BT 238.99 228.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 263.96 228.10 Td (expenses ) Tj ET Q q 0 0 0 rg BT 303.35 228.10 Td (in ) Tj ET Q q 0 0 0 rg BT 314.43 228.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.95 228.10 Td (last ) Tj ET Q q 0 0 0 rg BT 347.13 228.10 Td (three ) Tj ET Q q 0 0 0 rg BT 370.42 228.10 Td (years. ) Tj ET Q q 0 0 0 rg BT 397.32 228.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 416.17 228.10 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 457.78 228.10 Td (development ) Tj ET Q q 0 0 0 rg BT 512.73 228.10 Td (programs ) Tj ET Q q 0 0 0 rg BT 553.80 228.10 Td (could ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.10 Td (potentially ) Tj ET Q q 0 0 0 rg BT 81.32 216.10 Td (have ) Tj ET Q q 0 0 0 rg BT 102.74 216.10 Td (an ) Tj ET Q q 0 0 0 rg BT 114.73 216.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 144.49 216.10 Td (on ) Tj ET Q q 0 0 0 rg BT 157.04 216.10 Td (our ) Tj ET Q q 0 0 0 rg BT 172.92 216.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 207.11 216.10 Td (and ) Tj ET Q q 0 0 0 rg BT 224.10 216.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 260.53 216.10 Td (within ) Tj ET Q q 0 0 0 rg BT 288.63 216.10 Td (the ) Tj ET Q q 0 0 0 rg BT 303.40 216.10 Td (next ) Tj ET Q q 0 0 0 rg BT 323.16 216.10 Td (few ) Tj ET Q q 0 0 0 rg BT 340.70 216.10 Td (years ) Tj ET Q q 0 0 0 rg BT 364.35 216.10 Td (if ) Tj ET Q q 0 0 0 rg BT 373.01 216.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 416.65 216.10 Td (approvals ) Tj ET Q q 0 0 0 rg BT 458.08 216.10 Td (are ) Tj ET Q q 0 0 0 rg BT 472.83 216.10 Td (obtained ) Tj ET Q q 0 0 0 rg BT 509.81 216.10 Td (and ) Tj ET Q q 0 0 0 rg BT 526.80 216.10 Td (products ) Tj ET Q q 0 0 0 rg BT 563.79 216.10 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.10 Td (successfully ) Tj ET Q q 0 0 0 rg BT 87.38 204.10 Td (commercialized. ) Tj ET Q q 0 0 0 rg BT 156.05 204.10 Td (The ) Tj ET Q q 0 0 0 rg BT 174.10 204.10 Td (following ) Tj ET Q q 0 0 0 rg BT 215.48 204.10 Td (are ) Tj ET Q q 0 0 0 rg BT 230.19 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 244.91 204.10 Td (developments ) Tj ET Q q 0 0 0 rg BT 302.95 204.10 Td (in ) Tj ET Q q 0 0 0 rg BT 313.23 204.10 Td (our ) Tj ET Q q 0 0 0 rg BT 329.06 204.10 Td (marketed ) Tj ET Q q 0 0 0 rg BT 368.76 204.10 Td (products ) Tj ET Q q 0 0 0 rg BT 405.70 204.10 Td (and ) Tj ET Q q 0 0 0 rg BT 422.64 204.10 Td (our ) Tj ET Q q 0 0 0 rg BT 438.47 204.10 Td (late-stage ) Tj ET Q q 0 0 0 rg BT 479.28 204.10 Td (pipeline:) Tj ET Q endstream endobj 105 0 obj <> endobj 106 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (52) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 755.5 m 35.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 755.5 m 98.5 755.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 755.5 m 98.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 755.5 m 180.5 755.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 755.5 m 180.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 755.5 m 241.5 755.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 755.5 m 241.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 755.5 m 575.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 755.5 m 575.5 755.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 740.5 m 35.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 740.5 m 98.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 740.5 m 98.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 740.5 m 180.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 740.5 m 180.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 740.5 m 241.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 740.5 m 241.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 740.5 m 241.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 740.5 m 575.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 740.5 m 575.5 740.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 708.5 m 35.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 708.5 m 98.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 708.5 m 180.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 708.5 m 180.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 708.5 m 241.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 708.5 m 241.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 708.5 m 241.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 708.5 m 575.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 708.5 m 575.5 708.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 676.5 m 35.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 676.5 m 98.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 676.5 m 180.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 676.5 m 241.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 676.5 m 241.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 676.5 m 241.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 676.5 m 575.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 676.5 m 575.5 676.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 653.5 m 35.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 653.5 m 98.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 653.5 m 180.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 653.5 m 241.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 653.5 m 241.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 653.5 m 241.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 653.5 m 575.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 653.5 m 575.5 653.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 621.5 m 35.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 621.5 m 98.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 621.5 m 180.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 621.5 m 241.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 621.5 m 241.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 621.5 m 241.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 621.5 m 575.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 621.5 m 575.5 621.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 589.5 m 35.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 589.5 m 98.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 589.5 m 180.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 589.5 m 180.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 589.5 m 241.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 589.5 m 241.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 589.5 m 241.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 589.5 m 575.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 589.5 m 575.5 589.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 566.5 m 35.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 566.5 m 98.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 566.5 m 180.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 566.5 m 180.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 566.5 m 241.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 534.5 m 241.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 566.5 m 241.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 566.5 m 575.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 566.5 m 575.5 566.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 534.5 m 575.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 534.5 m 35.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 534.5 m 98.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 534.5 m 180.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 534.5 m 180.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 534.5 m 241.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 534.5 m 241.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 534.5 m 241.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 534.5 m 575.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 534.5 m 575.5 534.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 502.5 m 35.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 502.5 m 98.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 502.5 m 180.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 502.5 m 180.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 502.5 m 241.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 502.5 m 241.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 502.5 m 241.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 502.5 m 575.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 502.5 m 575.5 502.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 479.5 m 35.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 479.5 m 98.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 479.5 m 180.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 479.5 m 180.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 479.5 m 241.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 479.5 m 241.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 479.5 m 241.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 479.5 m 575.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 479.5 m 575.5 479.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 456.5 m 35.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 456.5 m 98.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 456.5 m 180.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 456.5 m 180.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 456.5 m 241.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 456.5 m 241.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 456.5 m 241.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 456.5 m 575.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 456.5 m 575.5 456.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 433.5 m 35.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 433.5 m 98.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 433.5 m 180.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 433.5 m 180.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 401.5 m 180.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 433.5 m 241.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 433.5 m 241.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 433.5 m 241.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 433.5 m 575.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 433.5 m 575.5 433.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 401.5 m 35.5 378.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 401.5 m 98.5 378.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 401.5 m 180.5 378.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 401.5 m 180.5 401.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 378.5 m 180.5 378.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 401.5 m 241.5 378.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 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250.5 m 98.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 250.5 m 180.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 250.5 m 241.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 250.5 m 241.5 250.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 250.5 m 241.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 250.5 m 575.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 250.5 m 575.5 250.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 218.5 m 35.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 218.5 m 98.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 218.5 m 180.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 218.5 m 180.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 218.5 m 241.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 218.5 m 241.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 218.5 m 575.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 218.5 m 575.5 218.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 186.5 m 575.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 186.5 m 35.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 186.5 m 98.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 163.5 m 180.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 186.5 m 180.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 186.5 m 241.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 186.5 m 241.5 186.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 163.5 m 241.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 186.5 m 575.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 163.5 m 575.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 163.5 m 35.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 163.5 m 98.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 163.5 m 180.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 163.5 m 180.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 163.5 m 241.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 163.5 m 241.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 131.5 m 241.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 163.5 m 241.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 163.5 m 575.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 163.5 m 575.5 163.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 131.5 m 35.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 131.5 m 98.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 131.5 m 180.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 131.5 m 241.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 131.5 m 241.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 131.5 m 575.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 131.5 m 575.5 131.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 81.5 m 98.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 81.5 m 180.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 81.5 m 241.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 81.5 m 575.5 81.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 41 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 41 m BT /F2 9.00 Tf ET q 0 0 0 rg BT 51.05 744.95 Td (Pr) Tj ET Q q 0 0 0 rg BT 60.46 744.95 Td (oduct) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 119.20 744.95 Td (Indication) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 201.50 744.95 Td (Date) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 381.00 744.95 Td (Developments) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 53.25 408.95 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 102.25 722.36 Td (Biliary ) Tj ET Q q 0 0 0 rg BT 129.41 722.36 Td (T) Tj ET Q q 0 0 0 rg BT 134.67 722.36 Td (ract Cancer) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 722.36 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 731.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 265.83 731.36 Td (and ) Tj ET Q q 0 0 0 rg BT 281.64 731.36 Td (Ono ) Tj ET Q q 0 0 0 rg BT 299.95 731.36 Td (announced ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 341.75 731.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 368.25 731.36 Td ( ) Tj ET Q q 0 0 0 rg BT 371.06 731.36 Td (was ) Tj ET Q q 0 0 0 rg BT 387.88 731.36 Td (designated ) Tj ET Q q 0 0 0 rg BT 429.18 731.36 Td (for ) Tj ET Q q 0 0 0 rg BT 442.49 731.36 Td (the ) Tj ET Q q 0 0 0 rg BT 456.30 731.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 493.10 731.36 Td (of ) Tj ET Q q 0 0 0 rg BT 503.41 731.36 Td (biliary ) Tj ET Q q 0 0 0 rg BT 529.72 731.36 Td (tract ) Tj ET Q q 0 0 0 rg BT 548.52 731.36 Td (cancer ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 722.36 Td (under ) Tj ET Q q 0 0 0 rg BT 267.85 722.36 Td (the ) Tj ET Q q 0 0 0 rg BT 282.21 722.36 Td (Sakigake ) Tj ET Q q 0 0 0 rg BT 318.56 722.36 Td (Designation ) Tj ET Q q 0 0 0 rg BT 365.42 722.36 Td (System ) Tj ET Q q 0 0 0 rg BT 395.28 722.36 Td (in ) Tj ET Q q 0 0 0 rg BT 405.64 722.36 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 431.75 722.36 Td (which ) Tj ET Q q 0 0 0 rg BT 457.10 722.36 Td (of) Tj ET Q q 0 0 0 rg BT 464.44 722.36 Td (fers ) Tj ET Q q 0 0 0 rg BT 481.29 722.36 Td (priority ) Tj ET Q q 0 0 0 rg BT 511.65 722.36 Td (consultation ) Tj ET Q q 0 0 0 rg BT 559.00 722.36 Td (and ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 713.36 Td (review) Tj ET Q q 0 0 0 rg BT 267.90 713.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 131.15 646.86 Td (cHL) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.00 694.86 Td (December) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 685.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 699.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 265.75 699.36 Td (and ) Tj ET Q q 0 0 0 rg BT 281.48 699.36 Td (Seattle ) Tj ET Q q 0 0 0 rg BT 308.71 699.36 Td (Genetics, ) Tj ET Q q 0 0 0 rg BT 345.18 699.36 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 361.66 699.36 Td (highlighted ) Tj ET Q q 0 0 0 rg BT 405.39 699.36 Td (an ) Tj ET Q q 0 0 0 rg BT 416.62 699.36 Td (updated ) Tj ET Q q 0 0 0 rg BT 447.85 699.36 Td (interim ) Tj ET Q q 0 0 0 rg BT 476.58 699.36 Td (results ) Tj ET Q q 0 0 0 rg BT 502.81 699.36 Td (from ) Tj ET Q q 0 0 0 rg BT 523.05 699.36 Td (the ) Tj ET Q q 0 0 0 rg BT 536.78 699.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 560.51 699.36 Td (I/II ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 690.36 Td (study ) Tj ET Q q 0 0 0 rg BT 267.14 690.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 308.26 690.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 334.75 690.36 Td ( ) Tj ET Q q 0 0 0 rg BT 338.39 690.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 355.02 690.36 Td (Adcetris) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 385.01 690.36 Td (* ) Tj ET Q q 0 0 0 rg BT 393.15 690.36 Td (in ) Tj ET Q q 0 0 0 rg BT 403.79 690.36 Td (relapsed/refractory ) Tj ET Q q 0 0 0 rg BT 475.38 690.36 Td (cHL. ) Tj ET Q q 0 0 0 rg BT 497.26 690.36 Td (Interim ) Tj ET Q q 0 0 0 rg BT 527.38 690.36 Td (results ) Tj ET Q q 0 0 0 rg BT 554.51 690.36 Td (were ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 681.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 284.25 681.36 Td (highlighted ) Tj ET Q q 0 0 0 rg BT 327.49 681.36 Td (in ) Tj ET Q q 0 0 0 rg BT 336.74 681.36 Td (June. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 662.86 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 667.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 264.95 667.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 305.88 667.36 Td (extended ) Tj ET Q q 0 0 0 rg BT 340.30 667.36 Td (follow-up ) Tj ET Q q 0 0 0 rg BT 377.74 667.36 Td (data ) Tj ET Q q 0 0 0 rg BT 394.67 667.36 Td (from ) Tj ET Q q 0 0 0 rg BT 414.10 667.36 Td (CheckMate-205, ) Tj ET Q q 0 0 0 rg BT 476.27 667.36 Td (a ) Tj ET Q q 0 0 0 rg BT 482.21 667.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 505.15 667.36 Td (II ) Tj ET Q q 0 0 0 rg BT 513.08 667.36 Td (study ) Tj ET Q q 0 0 0 rg BT 534.52 667.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 244.00 658.35 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 270.49 658.35 Td ( ) Tj ET Q q 0 0 0 rg BT 272.74 658.35 Td (in ) Tj ET Q q 0 0 0 rg BT 282.00 658.35 Td (patients ) Tj ET Q q 0 0 0 rg BT 312.24 658.35 Td (with ) Tj ET Q q 0 0 0 rg BT 330.49 658.35 Td (relapsed ) Tj ET Q q 0 0 0 rg BT 362.72 658.35 Td (or ) Tj ET Q q 0 0 0 rg BT 372.47 658.35 Td (progressed ) Tj ET Q q 0 0 0 rg BT 413.71 658.35 Td (cHL) Tj ET Q q 0 0 0 rg BT 429.37 658.35 Td ( ) Tj ET Q q 0 0 0 rg BT 431.62 658.35 Td (after ) Tj ET Q q 0 0 0 rg BT 450.35 658.35 Td (autologous ) Tj ET Q q 0 0 0 rg BT 492.10 658.35 Td (stem ) Tj ET Q q 0 0 0 rg BT 511.35 658.35 Td (cell ) Tj ET Q q 0 0 0 rg BT 526.59 658.35 Td (transplant.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 635.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 644.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 267.66 644.36 Td (and ) Tj ET Q q 0 0 0 rg BT 285.30 644.36 Td (Seattle ) Tj ET Q q 0 0 0 rg BT 314.43 644.36 Td (Genetics, ) Tj ET Q q 0 0 0 rg BT 352.82 644.36 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 371.20 644.36 Td (expanded ) Tj ET Q q 0 0 0 rg BT 410.33 644.36 Td (their ) Tj ET Q q 0 0 0 rg BT 431.47 644.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 462.60 644.36 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 514.73 644.36 Td (to ) Tj ET Q q 0 0 0 rg BT 526.38 644.36 Td (evaluate ) Tj ET Q q 0 0 0 rg BT 561.01 644.36 Td (the ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 635.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 291.34 635.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 301.19 635.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 327.69 635.36 Td ( ) Tj ET Q q 0 0 0 rg BT 330.04 635.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 345.39 635.36 Td (Adcetris*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 379.88 635.36 Td ( ) Tj ET Q q 0 0 0 rg BT 382.23 635.36 Td (\(brentuximab ) Tj ET Q q 0 0 0 rg BT 433.07 635.36 Td (vedotin\) ) Tj ET Q q 0 0 0 rg BT 465.41 635.36 Td (in ) Tj ET Q q 0 0 0 rg BT 474.76 635.36 Td (a ) Tj ET Q q 0 0 0 rg BT 481.11 635.36 Td (pivotal ) Tj ET Q q 0 0 0 rg BT 508.46 635.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 531.81 635.36 Td (III ) Tj ET Q q 0 0 0 rg BT 543.15 635.36 Td (study ) Tj ET Q q 0 0 0 rg BT 565.01 635.36 Td (in ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 626.36 Td (relapsed/refractory ) Tj ET Q q 0 0 0 rg BT 314.21 626.36 Td (or ) Tj ET Q q 0 0 0 rg BT 323.95 626.36 Td (transplant ) Tj ET Q q 0 0 0 rg BT 361.69 626.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 397.92 626.36 Td (cHL.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 603.36 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 612.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.51 612.36 Td ( ) Tj ET Q q 0 0 0 rg BT 263.91 612.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 297.79 612.36 Td (for ) Tj ET Q q 0 0 0 rg BT 310.69 612.36 Td (an ) Tj ET Q q 0 0 0 rg BT 321.58 612.36 Td (updated ) Tj ET Q q 0 0 0 rg BT 352.47 612.36 Td (indication ) Tj ET Q q 0 0 0 rg BT 390.86 612.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 403.75 612.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 430.25 612.36 Td ( ) Tj ET Q q 0 0 0 rg BT 432.65 612.36 Td (for ) Tj ET Q q 0 0 0 rg BT 445.54 612.36 Td (the ) Tj ET Q q 0 0 0 rg BT 458.94 612.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 495.32 612.36 Td (of ) Tj ET Q q 0 0 0 rg BT 505.22 612.36 Td (adult ) Tj ET Q q 0 0 0 rg BT 525.61 612.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 612.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 603.36 Td (cHL) Tj ET Q q 0 0 0 rg BT 259.66 603.36 Td ( ) Tj ET Q q 0 0 0 rg BT 261.72 603.36 Td (that ) Tj ET Q q 0 0 0 rg BT 277.29 603.36 Td (have ) Tj ET Q q 0 0 0 rg BT 296.34 603.36 Td (relapsed ) Tj ET Q q 0 0 0 rg BT 328.39 603.36 Td (or ) Tj ET Q q 0 0 0 rg BT 337.96 603.36 Td (progressed ) Tj ET Q q 0 0 0 rg BT 379.01 603.36 Td (after ) Tj ET Q q 0 0 0 rg BT 397.56 603.36 Td (auto-HSCT) Tj ET Q q 0 0 0 rg BT 438.90 603.36 Td ( ) Tj ET Q q 0 0 0 rg BT 440.96 603.36 Td (and ) Tj ET Q q 0 0 0 rg BT 456.02 603.36 Td (brentuximab ) Tj ET Q q 0 0 0 rg BT 503.58 603.36 Td (vedotin, ) Tj ET Q q 0 0 0 rg BT 534.89 603.36 Td (or ) Tj ET Q q 0 0 0 rg BT 544.45 603.36 Td (three ) Tj ET Q q 0 0 0 rg BT 564.51 603.36 Td (or ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 594.36 Td (more ) Tj ET Q q 0 0 0 rg BT 264.74 594.36 Td (lines ) Tj ET Q q 0 0 0 rg BT 283.99 594.36 Td (of ) Tj ET Q q 0 0 0 rg BT 293.74 594.36 Td (systemic ) Tj ET Q q 0 0 0 rg BT 327.48 594.36 Td (therapy ) Tj ET Q q 0 0 0 rg BT 356.72 594.36 Td (that ) Tj ET Q q 0 0 0 rg BT 372.47 594.36 Td (includes ) Tj ET Q q 0 0 0 rg BT 404.71 594.36 Td (auto-HSCT) Tj ET Q q 0 0 0 rg BT 445.54 594.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 126.00 559.86 Td (Gastric) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 580.36 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 571.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 580.36 Td (Approval ) Tj ET Q q 0 0 0 rg BT 281.09 580.36 Td (in ) Tj ET Q q 0 0 0 rg BT 291.19 580.36 Td (Japan ) Tj ET Q q 0 0 0 rg BT 314.78 580.36 Td (for ) Tj ET Q q 0 0 0 rg BT 328.37 580.36 Td (the ) Tj ET Q q 0 0 0 rg BT 342.46 580.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 379.54 580.36 Td (of ) Tj ET Q q 0 0 0 rg BT 390.13 580.36 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 438.20 580.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 475.28 580.36 Td (or ) Tj ET Q q 0 0 0 rg BT 485.87 580.36 Td (recurrent ) Tj ET Q q 0 0 0 rg BT 521.45 580.36 Td (gastric ) Tj ET Q q 0 0 0 rg BT 548.53 580.36 Td (cancer ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 571.36 Td (which ) Tj ET Q q 0 0 0 rg BT 268.24 571.36 Td (has ) Tj ET Q q 0 0 0 rg BT 282.49 571.36 Td (progressed ) Tj ET Q q 0 0 0 rg BT 323.73 571.36 Td (after ) Tj ET Q q 0 0 0 rg BT 342.46 571.36 Td (chemotherapy) Tj ET Q q 0 0 0 rg BT 393.15 571.36 Td (, ) Tj ET Q q 0 0 0 rg BT 397.36 571.36 Td (received ) Tj ET Q q 0 0 0 rg BT 430.08 571.36 Td (by ) Tj ET Q q 0 0 0 rg BT 441.33 571.36 Td (our ) Tj ET Q q 0 0 0 rg BT 455.58 571.36 Td (alliance ) Tj ET Q q 0 0 0 rg BT 485.81 571.36 Td (partner) Tj ET Q q 0 0 0 rg BT 511.11 571.36 Td (, ) Tj ET Q q 0 0 0 rg BT 515.43 571.36 Td (Ono.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 186.35 548.36 Td (January 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 557.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.18 557.36 Td (results ) Tj ET Q q 0 0 0 rg BT 314.37 557.36 Td (of ) Tj ET Q q 0 0 0 rg BT 324.56 557.36 Td (ONO-4538-12, ) Tj ET Q q 0 0 0 rg BT 382.00 557.36 Td (a ) Tj ET Q q 0 0 0 rg BT 388.69 557.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 412.38 557.36 Td (III ) Tj ET Q q 0 0 0 rg BT 424.06 557.36 Td (study ) Tj ET Q q 0 0 0 rg BT 446.25 557.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 486.43 557.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 512.93 557.36 Td ( ) Tj ET Q q 0 0 0 rg BT 515.62 557.36 Td (in ) Tj ET Q q 0 0 0 rg BT 525.31 557.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 557.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 548.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 284.99 548.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 312.47 548.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 349.45 548.36 Td (gastric ) Tj ET Q q 0 0 0 rg BT 376.44 548.36 Td (cancer ) Tj ET Q q 0 0 0 rg BT 402.91 548.36 Td (refractory ) Tj ET Q q 0 0 0 rg BT 441.38 548.36 Td (to ) Tj ET Q q 0 0 0 rg BT 451.38 548.36 Td (or ) Tj ET Q q 0 0 0 rg BT 461.88 548.36 Td (intolerant ) Tj ET Q q 0 0 0 rg BT 499.36 548.36 Td (of ) Tj ET Q q 0 0 0 rg BT 509.86 548.36 Td (standard ) Tj ET Q q 0 0 0 rg BT 543.34 548.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 569.75 548.36 Td (. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 539.36 Td (Ono, ) Tj ET Q q 0 0 0 rg BT 264.00 539.36 Td (our ) Tj ET Q q 0 0 0 rg BT 278.25 539.36 Td (alliance ) Tj ET Q q 0 0 0 rg BT 308.48 539.36 Td (partner) Tj ET Q q 0 0 0 rg BT 333.60 539.36 Td (, ) Tj ET Q q 0 0 0 rg BT 338.10 539.36 Td (conducted ) Tj ET Q q 0 0 0 rg BT 377.33 539.36 Td (the ) Tj ET Q q 0 0 0 rg BT 390.58 539.36 Td (study) Tj ET Q q 0 0 0 rg BT 409.50 539.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 128.70 516.36 Td (GBM) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 516.36 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 525.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.17 525.36 Td (CheckMate-143, ) Tj ET Q q 0 0 0 rg BT 349.09 525.36 Td (a ) Tj ET Q q 0 0 0 rg BT 354.77 525.36 Td (randomized ) Tj ET Q q 0 0 0 rg BT 398.94 525.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 421.62 525.36 Td (III ) Tj ET Q q 0 0 0 rg BT 432.30 525.36 Td (study ) Tj ET Q q 0 0 0 rg BT 453.49 525.36 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 492.66 525.36 Td (the ) Tj ET Q q 0 0 0 rg BT 505.34 525.36 Td (ef) Tj ET Q q 0 0 0 rg BT 512.17 525.36 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 535.83 525.36 Td (and ) Tj ET Q q 0 0 0 rg BT 550.51 525.36 Td (safety ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 516.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 254.57 516.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 281.06 516.36 Td ( ) Tj ET Q q 0 0 0 rg BT 284.14 516.36 Td (in ) Tj ET Q q 0 0 0 rg BT 294.21 516.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 325.27 516.36 Td (with ) Tj ET Q q 0 0 0 rg BT 344.34 516.36 Td (first ) Tj ET Q q 0 0 0 rg BT 361.91 516.36 Td (recurrence ) Tj ET Q q 0 0 0 rg BT 402.95 516.36 Td (of ) Tj ET Q q 0 0 0 rg BT 413.52 516.36 Td (GBM ) Tj ET Q q 0 0 0 rg BT 437.10 516.36 Td (did ) Tj ET Q q 0 0 0 rg BT 451.67 516.36 Td (not ) Tj ET Q q 0 0 0 rg BT 466.24 516.36 Td (meet ) Tj ET Q q 0 0 0 rg BT 486.80 516.36 Td (its ) Tj ET Q q 0 0 0 rg BT 498.38 516.36 Td (primary ) Tj ET Q q 0 0 0 rg BT 529.94 516.36 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 564.51 516.36 Td (of ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 507.36 Td (improved ) Tj ET Q q 0 0 0 rg BT 280.74 507.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 307.98 507.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 339.23 507.36 Td (over ) Tj ET Q q 0 0 0 rg BT 357.47 507.36 Td (bevacizumab ) Tj ET Q q 0 0 0 rg BT 407.19 507.36 Td (monotherapy) Tj ET Q q 0 0 0 rg BT 454.09 507.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.70 488.86 Td (HCC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 493.36 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 484.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 493.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.76 493.36 Td ( ) Tj ET Q q 0 0 0 rg BT 263.57 493.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 297.12 493.36 Td (for ) Tj ET Q q 0 0 0 rg BT 309.67 493.36 Td (the ) Tj ET Q q 0 0 0 rg BT 322.73 493.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 358.77 493.36 Td (of ) Tj ET Q q 0 0 0 rg BT 368.33 493.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 398.38 493.36 Td (with ) Tj ET Q q 0 0 0 rg BT 416.45 493.36 Td (HCC, ) Tj ET Q q 0 0 0 rg BT 439.26 493.36 Td (a ) Tj ET Q q 0 0 0 rg BT 445.32 493.36 Td (type ) Tj ET Q q 0 0 0 rg BT 462.87 493.36 Td (of ) Tj ET Q q 0 0 0 rg BT 472.43 493.36 Td (liver ) Tj ET Q q 0 0 0 rg BT 490.99 493.36 Td (cancer) Tj ET Q q 0 0 0 rg BT 514.28 493.36 Td (, ) Tj ET Q q 0 0 0 rg BT 518.41 493.36 Td (who ) Tj ET Q q 0 0 0 rg BT 535.97 493.36 Td (have ) Tj ET Q q 0 0 0 rg BT 555.02 493.36 Td (been ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 484.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 284.25 484.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 310.98 484.36 Td (with ) Tj ET Q q 0 0 0 rg BT 329.23 484.36 Td (sorafenib.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.45 454.36 Td (HNC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 465.86 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 470.36 Td (EC ) Tj ET Q q 0 0 0 rg BT 258.04 470.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 292.08 470.36 Td (for ) Tj ET Q q 0 0 0 rg BT 305.11 470.36 Td (the ) Tj ET Q q 0 0 0 rg BT 318.65 470.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 355.18 470.36 Td (of ) Tj ET Q q 0 0 0 rg BT 365.22 470.36 Td (SCCHN ) Tj ET Q q 0 0 0 rg BT 397.78 470.36 Td (in ) Tj ET Q q 0 0 0 rg BT 407.32 470.36 Td (adults ) Tj ET Q q 0 0 0 rg BT 431.37 470.36 Td (progressing ) Tj ET Q q 0 0 0 rg BT 475.90 470.36 Td (on ) Tj ET Q q 0 0 0 rg BT 487.45 470.36 Td (or ) Tj ET Q q 0 0 0 rg BT 497.49 470.36 Td (after ) Tj ET Q q 0 0 0 rg BT 516.52 470.36 Td (platinum-based ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 461.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 270.69 461.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 188.60 442.86 Td (March 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 447.36 Td (Approval ) Tj ET Q q 0 0 0 rg BT 279.88 447.36 Td (for ) Tj ET Q q 0 0 0 rg BT 292.26 447.36 Td (the ) Tj ET Q q 0 0 0 rg BT 305.14 447.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 341.00 447.36 Td (of ) Tj ET Q q 0 0 0 rg BT 350.39 447.36 Td (recurrent ) Tj ET Q q 0 0 0 rg BT 384.75 447.36 Td (or ) Tj ET Q q 0 0 0 rg BT 394.13 447.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 432.50 447.36 Td (HNC ) Tj ET Q q 0 0 0 rg BT 453.39 447.36 Td (in ) Tj ET Q q 0 0 0 rg BT 462.27 447.36 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 486.90 447.36 Td (received ) Tj ET Q q 0 0 0 rg BT 519.26 447.36 Td (by ) Tj ET Q q 0 0 0 rg BT 530.15 447.36 Td (our ) Tj ET Q q 0 0 0 rg BT 544.03 447.36 Td (alliance ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 438.36 Td (partner) Tj ET Q q 0 0 0 rg BT 269.30 438.36 Td (, ) Tj ET Q q 0 0 0 rg BT 273.62 438.36 Td (Ono.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 130.05 415.36 Td (HPV) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 415.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 424.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.34 424.36 Td (data ) Tj ET Q q 0 0 0 rg BT 304.19 424.36 Td (from ) Tj ET Q q 0 0 0 rg BT 323.54 424.36 Td (a ) Tj ET Q q 0 0 0 rg BT 329.39 424.36 Td (cohort ) Tj ET Q q 0 0 0 rg BT 354.23 424.36 Td (of ) Tj ET Q q 0 0 0 rg BT 363.58 424.36 Td (the ) Tj ET Q q 0 0 0 rg BT 376.43 424.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 399.29 424.36 Td (I/II ) Tj ET Q q 0 0 0 rg BT 412.63 424.36 Td (CheckMate-358 ) Tj ET Q q 0 0 0 rg BT 472.47 424.36 Td (study ) Tj ET Q q 0 0 0 rg BT 493.82 424.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 533.16 424.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 559.66 424.36 Td ( ) Tj ET Q q 0 0 0 rg BT 561.51 424.36 Td (for ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 415.36 Td (the ) Tj ET Q q 0 0 0 rg BT 257.42 415.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 293.84 415.36 Td (of ) Tj ET Q q 0 0 0 rg BT 303.76 415.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 334.19 415.36 Td (with ) Tj ET Q q 0 0 0 rg BT 352.61 415.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 389.02 415.36 Td (cervical, ) Tj ET Q q 0 0 0 rg BT 422.18 415.36 Td (vaginal ) Tj ET Q q 0 0 0 rg BT 451.10 415.36 Td (and ) Tj ET Q q 0 0 0 rg BT 466.52 415.36 Td (vulvar ) Tj ET Q q 0 0 0 rg BT 491.94 415.36 Td (cancers, ) Tj ET Q q 0 0 0 rg BT 523.60 415.36 Td (all ) Tj ET Q q 0 0 0 rg BT 535.02 415.36 Td (associated ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 406.36 Td (with ) Tj ET Q q 0 0 0 rg BT 262.25 406.36 Td (infection ) Tj ET Q q 0 0 0 rg BT 296.49 406.36 Td (by ) Tj ET Q q 0 0 0 rg BT 307.74 406.36 Td (HPV) Tj ET Q q 0 0 0 rg BT 324.58 406.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 126.45 387.86 Td (mCRC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 187.35 387.86 Td (August 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 392.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.76 392.36 Td ( ) Tj ET Q q 0 0 0 rg BT 263.30 392.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 296.57 392.36 Td (for ) Tj ET Q q 0 0 0 rg BT 308.86 392.36 Td (the ) Tj ET Q q 0 0 0 rg BT 321.64 392.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 357.41 392.36 Td (of ) Tj ET Q q 0 0 0 rg BT 366.70 392.36 Td (adult ) Tj ET Q q 0 0 0 rg BT 386.49 392.36 Td (and ) Tj ET Q q 0 0 0 rg BT 401.27 392.36 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 434.54 392.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 464.33 392.36 Td (with ) Tj ET Q q 0 0 0 rg BT 482.12 392.36 Td (MSI-H ) Tj ET Q q 0 0 0 rg BT 509.41 392.36 Td (or ) Tj ET Q q 0 0 0 rg BT 518.69 392.36 Td (dMMR ) Tj ET Q q 0 0 0 rg BT 546.99 392.36 Td (mCRC ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 383.36 Td (that ) Tj ET Q q 0 0 0 rg BT 259.60 383.36 Td (has ) Tj ET Q q 0 0 0 rg BT 273.71 383.36 Td (progressed ) Tj ET Q q 0 0 0 rg BT 314.81 383.36 Td (following ) Tj ET Q q 0 0 0 rg BT 351.92 383.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 388.01 383.36 Td (with ) Tj ET Q q 0 0 0 rg BT 406.12 383.36 Td (a ) Tj ET Q q 0 0 0 rg BT 412.22 383.36 Td (fluoropyrimidine, ) Tj ET Q q 0 0 0 rg BT 478.07 383.36 Td (oxaliplatin ) Tj ET Q q 0 0 0 rg BT 518.67 383.36 Td (and ) Tj ET Q q 0 0 0 rg BT 533.78 383.36 Td (irinotecan.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 119.75 296.36 Td (Melanoma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.00 364.86 Td (December) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 355.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 369.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.76 369.36 Td ( ) Tj ET Q q 0 0 0 rg BT 264.40 369.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 298.78 369.36 Td (of ) Tj ET Q q 0 0 0 rg BT 309.17 369.36 Td (injection ) Tj ET Q q 0 0 0 rg BT 343.55 369.36 Td (for ) Tj ET Q q 0 0 0 rg BT 356.94 369.36 Td (intravenous ) Tj ET Q q 0 0 0 rg BT 401.82 369.36 Td (use ) Tj ET Q q 0 0 0 rg BT 416.71 369.36 Td (for ) Tj ET Q q 0 0 0 rg BT 430.09 369.36 Td (the ) Tj ET Q q 0 0 0 rg BT 443.98 369.36 Td (adjuvant ) Tj ET Q q 0 0 0 rg BT 477.86 369.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 514.73 369.36 Td (of ) Tj ET Q q 0 0 0 rg BT 525.12 369.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.01 369.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 360.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 284.92 360.36 Td (with ) Tj ET Q q 0 0 0 rg BT 304.35 360.36 Td (involvement ) Tj ET Q q 0 0 0 rg BT 352.77 360.36 Td (of ) Tj ET Q q 0 0 0 rg BT 363.70 360.36 Td (lymph ) Tj ET Q q 0 0 0 rg BT 390.13 360.36 Td (nodes ) Tj ET Q q 0 0 0 rg BT 414.56 360.36 Td (or ) Tj ET Q q 0 0 0 rg BT 425.49 360.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 465.41 360.36 Td (disease ) Tj ET Q q 0 0 0 rg BT 494.83 360.36 Td (who ) Tj ET Q q 0 0 0 rg BT 513.76 360.36 Td (have ) Tj ET Q q 0 0 0 rg BT 534.18 360.36 Td (under) Tj ET Q q 0 0 0 rg BT 554.59 360.36 Td (gone ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 351.36 Td (complete ) Tj ET Q q 0 0 0 rg BT 279.24 351.36 Td (resection.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 185.85 328.36 Td (October 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 337.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.23 337.36 Td (the ) Tj ET Q q 0 0 0 rg BT 301.96 337.36 Td (EMA) Tj ET Q q 0 0 0 rg BT 321.71 337.36 Td ( ) Tj ET Q q 0 0 0 rg BT 324.20 337.36 Td (validated ) Tj ET Q q 0 0 0 rg BT 359.92 337.36 Td (its ) Tj ET Q q 0 0 0 rg BT 371.16 337.36 Td (type ) Tj ET Q q 0 0 0 rg BT 389.40 337.36 Td (II ) Tj ET Q q 0 0 0 rg BT 398.13 337.36 Td (variation ) Tj ET Q q 0 0 0 rg BT 432.85 337.36 Td (application ) Tj ET Q q 0 0 0 rg BT 475.58 337.36 Td (which ) Tj ET Q q 0 0 0 rg BT 500.31 337.36 Td (seeks ) Tj ET Q q 0 0 0 rg BT 522.54 337.36 Td (to ) Tj ET Q q 0 0 0 rg BT 532.28 337.36 Td (expand ) Tj ET Q q 0 0 0 rg BT 561.01 337.36 Td (the ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 328.36 Td (current ) Tj ET Q q 0 0 0 rg BT 271.85 328.36 Td (indications ) Tj ET Q q 0 0 0 rg BT 313.71 328.36 Td (to ) Tj ET Q q 0 0 0 rg BT 323.07 328.36 Td (include ) Tj ET Q q 0 0 0 rg BT 351.93 328.36 Td (the ) Tj ET Q q 0 0 0 rg BT 365.28 328.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 401.63 328.36 Td (of ) Tj ET Q q 0 0 0 rg BT 411.49 328.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 441.85 328.36 Td (with ) Tj ET Q q 0 0 0 rg BT 460.22 328.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 500.06 328.36 Td (who ) Tj ET Q q 0 0 0 rg BT 517.93 328.36 Td (are ) Tj ET Q q 0 0 0 rg BT 531.28 328.36 Td (at ) Tj ET Q q 0 0 0 rg BT 540.14 328.36 Td (high ) Tj ET Q q 0 0 0 rg BT 558.50 328.36 Td (risk ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 319.36 Td (of ) Tj ET Q q 0 0 0 rg BT 253.75 319.36 Td (disease ) Tj ET Q q 0 0 0 rg BT 281.99 319.36 Td (recurrence ) Tj ET Q q 0 0 0 rg BT 322.20 319.36 Td (following ) Tj ET Q q 0 0 0 rg BT 359.45 319.36 Td (complete ) Tj ET Q q 0 0 0 rg BT 394.68 319.36 Td (sur) Tj ET Q q 0 0 0 rg BT 405.60 319.36 Td (gical ) Tj ET Q q 0 0 0 rg BT 425.26 319.36 Td (resection.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 300.86 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 291.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 305.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.45 305.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 325.39 305.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 344.34 305.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 370.84 305.36 Td ( ) Tj ET Q q 0 0 0 rg BT 373.80 305.36 Td (resulted ) Tj ET Q q 0 0 0 rg BT 405.24 305.36 Td (in ) Tj ET Q q 0 0 0 rg BT 415.20 305.36 Td (significant ) Tj ET Q q 0 0 0 rg BT 456.15 305.36 Td (improvement ) Tj ET Q q 0 0 0 rg BT 507.10 305.36 Td (in ) Tj ET Q q 0 0 0 rg BT 517.05 305.36 Td (recurrence-free ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 296.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 275.69 296.36 Td (compared ) Tj ET Q q 0 0 0 rg BT 313.87 296.36 Td (to ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 323.57 296.36 Td (Y) Tj ET Q q 0 0 0 rg BT 327.75 296.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 347.74 296.36 Td ( ) Tj ET Q q 0 0 0 rg BT 350.44 296.36 Td (in ) Tj ET Q q 0 0 0 rg BT 360.13 296.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 390.83 296.36 Td (with ) Tj ET Q q 0 0 0 rg BT 409.52 296.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 430.71 296.36 Td (IIIb/c ) Tj ET Q q 0 0 0 rg BT 453.40 296.36 Td (or ) Tj ET Q q 0 0 0 rg BT 463.59 296.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 484.79 296.36 Td (IV) Tj ET Q q 0 0 0 rg BT 494.12 296.36 Td ( ) Tj ET Q q 0 0 0 rg BT 496.82 296.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 537.00 296.36 Td (following ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 287.36 Td (complete ) Tj ET Q q 0 0 0 rg BT 279.24 287.36 Td (sur) Tj ET Q q 0 0 0 rg BT 290.07 287.36 Td (gical ) Tj ET Q q 0 0 0 rg BT 309.81 287.36 Td (resection.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.85 264.36 Td (July 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 273.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.98 273.36 Td (a ) Tj ET Q q 0 0 0 rg BT 294.47 273.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 317.96 273.36 Td (III ) Tj ET Q q 0 0 0 rg BT 329.45 273.36 Td (study ) Tj ET Q q 0 0 0 rg BT 351.45 273.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 391.42 273.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 417.92 273.36 Td ( ) Tj ET Q q 0 0 0 rg BT 420.41 273.36 Td (versus ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 445.90 273.36 Td (Y) Tj ET Q q 0 0 0 rg BT 450.08 273.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 470.07 273.36 Td ( ) Tj ET Q q 0 0 0 rg BT 472.56 273.36 Td (in ) Tj ET Q q 0 0 0 rg BT 482.06 273.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 512.55 273.36 Td (with ) Tj ET Q q 0 0 0 rg BT 531.04 273.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 552.03 273.36 Td (IIIb/c ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 264.36 Td (or ) Tj ET Q q 0 0 0 rg BT 252.82 264.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 272.63 264.36 Td (IV) Tj ET Q q 0 0 0 rg BT 281.96 264.36 Td ( ) Tj ET Q q 0 0 0 rg BT 283.28 264.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 322.08 264.36 Td (who ) Tj ET Q q 0 0 0 rg BT 338.90 264.36 Td (are ) Tj ET Q q 0 0 0 rg BT 351.20 264.36 Td (at ) Tj ET Q q 0 0 0 rg BT 359.02 264.36 Td (high ) Tj ET Q q 0 0 0 rg BT 376.34 264.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 391.16 264.36 Td (of ) Tj ET Q q 0 0 0 rg BT 399.97 264.36 Td (recurrence ) Tj ET Q q 0 0 0 rg BT 439.25 264.36 Td (following ) Tj ET Q q 0 0 0 rg BT 475.57 264.36 Td (complete ) Tj ET Q q 0 0 0 rg BT 509.87 264.36 Td (sur) Tj ET Q q 0 0 0 rg BT 520.71 264.36 Td (gical ) Tj ET Q q 0 0 0 rg BT 539.52 264.36 Td (resection ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 255.36 Td (met ) Tj ET Q q 0 0 0 rg BT 259.75 255.36 Td (its ) Tj ET Q q 0 0 0 rg BT 270.50 255.36 Td (primary ) Tj ET Q q 0 0 0 rg BT 301.24 255.36 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 334.98 255.36 Td (of ) Tj ET Q q 0 0 0 rg BT 344.73 255.36 Td (recurrence-free ) Tj ET Q q 0 0 0 rg BT 401.93 255.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 433.17 255.36 Td (at ) Tj ET Q q 0 0 0 rg BT 441.92 255.36 Td (a ) Tj ET Q q 0 0 0 rg BT 448.16 255.36 Td (planned ) Tj ET Q q 0 0 0 rg BT 478.90 255.36 Td (interim ) Tj ET Q q 0 0 0 rg BT 507.14 255.36 Td (analysis.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 232.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 241.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.25 241.36 Td (proof-of-concept ) Tj ET Q q 0 0 0 rg BT 349.97 241.36 Td (data ) Tj ET Q q 0 0 0 rg BT 366.72 241.36 Td (from ) Tj ET Q q 0 0 0 rg BT 385.97 241.36 Td (the ) Tj ET Q q 0 0 0 rg BT 398.73 241.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 421.48 241.36 Td (I/IIa ) Tj ET Q q 0 0 0 rg BT 438.73 241.36 Td (study ) Tj ET Q q 0 0 0 rg BT 459.99 241.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 472.24 241.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 498.73 241.36 Td ( ) Tj ET Q q 0 0 0 rg BT 500.49 241.36 Td (in ) Tj ET Q q 0 0 0 rg BT 509.25 241.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 556.00 241.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 232.36 Td (BMS-986016, ) Tj ET Q q 0 0 0 rg BT 297.67 232.36 Td (an ) Tj ET Q q 0 0 0 rg BT 308.57 232.36 Td (investigational ) Tj ET Q q 0 0 0 rg BT 363.96 232.36 Td (anti-LAG-3 ) Tj ET Q q 0 0 0 rg BT 408.86 232.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 435.26 232.36 Td (, ) Tj ET Q q 0 0 0 rg BT 439.92 232.36 Td (in ) Tj ET Q q 0 0 0 rg BT 449.32 232.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 479.72 232.36 Td (with ) Tj ET Q q 0 0 0 rg BT 498.13 232.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 534.52 232.36 Td (melanoma ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 223.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 284.25 223.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 310.98 223.36 Td (with ) Tj ET Q q 0 0 0 rg BT 329.23 223.36 Td (anti-PD-1/PD-L1 ) Tj ET Q q 0 0 0 rg BT 393.97 223.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 420.37 223.36 Td (. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.20 188.86 Td (mUC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 200.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 209.36 Td (EC ) Tj ET Q q 0 0 0 rg BT 260.69 209.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 297.37 209.36 Td (for ) Tj ET Q q 0 0 0 rg BT 313.06 209.36 Td (the ) Tj ET Q q 0 0 0 rg BT 329.24 209.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 368.42 209.36 Td (of ) Tj ET Q q 0 0 0 rg BT 381.10 209.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 414.29 209.36 Td (with ) Tj ET Q q 0 0 0 rg BT 435.48 209.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 478.67 209.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 508.34 209.36 Td (locally ) Tj ET Q q 0 0 0 rg BT 538.02 209.36 Td (advanced ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 200.36 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 290.93 200.36 Td (or ) Tj ET Q q 0 0 0 rg BT 300.39 200.36 Td (mUC, ) Tj ET Q q 0 0 0 rg BT 324.11 200.36 Td (a ) Tj ET Q q 0 0 0 rg BT 330.06 200.36 Td (type ) Tj ET Q q 0 0 0 rg BT 347.52 200.36 Td (of ) Tj ET Q q 0 0 0 rg BT 356.98 200.36 Td (bladder ) Tj ET Q q 0 0 0 rg BT 385.92 200.36 Td (cancer) Tj ET Q q 0 0 0 rg BT 409.22 200.36 Td (, ) Tj ET Q q 0 0 0 rg BT 413.25 200.36 Td (in ) Tj ET Q q 0 0 0 rg BT 422.21 200.36 Td (adults ) Tj ET Q q 0 0 0 rg BT 445.67 200.36 Td (after ) Tj ET Q q 0 0 0 rg BT 464.12 200.36 Td (failure ) Tj ET Q q 0 0 0 rg BT 489.56 200.36 Td (of ) Tj ET Q q 0 0 0 rg BT 499.02 200.36 Td (platinum-containing ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 191.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 270.69 191.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 184.10 172.86 Td (February 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 177.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.51 177.36 Td ( ) Tj ET Q q 0 0 0 rg BT 265.14 177.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 300.26 177.36 Td (for ) Tj ET Q q 0 0 0 rg BT 314.39 177.36 Td (the ) Tj ET Q q 0 0 0 rg BT 329.02 177.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 366.63 177.36 Td (of ) Tj ET Q q 0 0 0 rg BT 377.76 177.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 409.39 177.36 Td (with ) Tj ET Q q 0 0 0 rg BT 429.02 177.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 470.65 177.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 498.77 177.36 Td (locally ) Tj ET Q q 0 0 0 rg BT 526.89 177.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 564.50 177.36 Td (or ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 168.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 282.73 168.36 Td (urothelial ) Tj ET Q q 0 0 0 rg BT 319.47 168.36 Td (carcinoma, ) Tj ET Q q 0 0 0 rg BT 361.45 168.36 Td (a ) Tj ET Q q 0 0 0 rg BT 367.69 168.36 Td (type ) Tj ET Q q 0 0 0 rg BT 385.44 168.36 Td (of ) Tj ET Q q 0 0 0 rg BT 395.19 168.36 Td (bladder ) Tj ET Q q 0 0 0 rg BT 424.42 168.36 Td (cancer) Tj ET Q q 0 0 0 rg BT 447.40 168.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 105.10 120.36 Td (Multiple Myeloma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.00 149.86 Td (December) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 140.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 154.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.75 154.36 Td (the ) Tj ET Q q 0 0 0 rg BT 301.00 154.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 318.51 154.36 Td ( ) Tj ET Q q 0 0 0 rg BT 320.77 154.36 Td (lifted ) Tj ET Q q 0 0 0 rg BT 342.02 154.36 Td (partial ) Tj ET Q q 0 0 0 rg BT 367.26 154.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 396.01 154.36 Td (holds ) Tj ET Q q 0 0 0 rg BT 417.77 154.36 Td (placed ) Tj ET Q q 0 0 0 rg BT 443.51 154.36 Td (on ) Tj ET Q q 0 0 0 rg BT 454.77 154.36 Td (CheckMate-039 ) Tj ET Q q 0 0 0 rg BT 515.01 154.36 Td (and ) Tj ET Q q 0 0 0 rg BT 530.26 154.36 Td (CA204142, ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 145.36 Td (two ) Tj ET Q q 0 0 0 rg BT 260.46 145.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 289.91 145.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 317.87 145.36 Td (investigating) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 364.36 145.36 Td ( ) Tj ET Q q 0 0 0 rg BT 367.32 145.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 393.82 145.36 Td ( ) Tj ET Q q 0 0 0 rg BT 396.78 145.36 Td (based ) Tj ET Q q 0 0 0 rg BT 420.23 145.36 Td (combinations ) Tj ET Q q 0 0 0 rg BT 471.69 145.36 Td (in ) Tj ET Q q 0 0 0 rg BT 481.65 145.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 512.60 145.36 Td (with ) Tj ET Q q 0 0 0 rg BT 531.56 145.36 Td (relapsed ) Tj ET Q q 0 0 0 rg BT 564.51 145.36 Td (or ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 136.36 Td (refractory ) Tj ET Q q 0 0 0 rg BT 281.72 136.36 Td (multiple ) Tj ET Q q 0 0 0 rg BT 313.97 136.36 Td (myeloma.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 108.86 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 99.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 122.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.02 122.36 Td (the ) Tj ET Q q 0 0 0 rg BT 301.55 122.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 319.06 122.36 Td ( ) Tj ET Q q 0 0 0 rg BT 321.60 122.36 Td (placed ) Tj ET Q q 0 0 0 rg BT 347.61 122.36 Td (partial ) Tj ET Q q 0 0 0 rg BT 373.14 122.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 402.16 122.36 Td (holds ) Tj ET Q q 0 0 0 rg BT 424.20 122.36 Td (on ) Tj ET Q q 0 0 0 rg BT 435.73 122.36 Td (CheckMate-602, ) Tj ET Q q 0 0 0 rg BT 498.50 122.36 Td (CheckMate-039 ) Tj ET Q q 0 0 0 rg BT 559.01 122.36 Td (and ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 113.36 Td (CA204142, ) Tj ET Q q 0 0 0 rg BT 288.13 113.36 Td (three ) Tj ET Q q 0 0 0 rg BT 308.50 113.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 337.37 113.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 364.75 113.36 Td (investigating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 413.62 113.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 440.12 113.36 Td ( ) Tj ET Q q 0 0 0 rg BT 442.50 113.36 Td (based ) Tj ET Q q 0 0 0 rg BT 465.37 113.36 Td (combinations ) Tj ET Q q 0 0 0 rg BT 516.25 113.36 Td (in ) Tj ET Q q 0 0 0 rg BT 525.63 113.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 113.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 104.36 Td (relapsed ) Tj ET Q q 0 0 0 rg BT 275.44 104.36 Td (or ) Tj ET Q q 0 0 0 rg BT 284.40 104.36 Td (refractory ) Tj ET Q q 0 0 0 rg BT 321.33 104.36 Td (multiple ) Tj ET Q q 0 0 0 rg BT 352.79 104.36 Td (myeloma. ) Tj ET Q q 0 0 0 rg BT 389.88 104.36 Td (This ) Tj ET Q q 0 0 0 rg BT 407.34 104.36 Td (partial ) Tj ET Q q 0 0 0 rg BT 431.79 104.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 459.73 104.36 Td (hold ) Tj ET Q q 0 0 0 rg BT 477.19 104.36 Td (is ) Tj ET Q q 0 0 0 rg BT 484.65 104.36 Td (related ) Tj ET Q q 0 0 0 rg BT 510.59 104.36 Td (to ) Tj ET Q q 0 0 0 rg BT 519.05 104.36 Td (risks ) Tj ET Q q 0 0 0 rg BT 537.52 104.36 Td (identified ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 95.36 Td (in ) Tj ET Q q 0 0 0 rg BT 255.11 95.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 284.21 95.36 Td (studying ) Tj ET Q q 0 0 0 rg BT 319.32 95.36 Td (another ) Tj ET Q q 0 0 0 rg BT 350.41 95.36 Td (anti-PD-1 ) Tj ET Q q 0 0 0 rg BT 390.01 95.36 Td (agent, ) Tj ET Q q 0 0 0 rg BT 415.86 95.36 Td (pembrolizumab, ) Tj ET Q q 0 0 0 rg BT 478.69 95.36 Td (in ) Tj ET Q q 0 0 0 rg BT 489.80 95.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 521.90 95.36 Td (with ) Tj ET Q q 0 0 0 rg BT 542.00 95.36 Td (multiple ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 86.36 Td (myeloma.) Tj ET Q endstream endobj 107 0 obj <> endobj 108 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (53) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 750.5 m 98.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 750.5 m 180.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 750.5 m 241.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 750.5 m 575.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 750.5 m 35.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 750.5 m 98.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 750.5 m 180.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 750.5 m 241.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 750.5 m 575.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 691.5 m 35.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 691.5 m 98.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 691.5 m 180.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 691.5 m 241.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 691.5 m 241.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 691.5 m 575.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 691.5 m 575.5 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 659.5 m 35.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 659.5 m 98.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 659.5 m 180.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 659.5 m 241.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 659.5 m 241.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 659.5 m 575.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 659.5 m 575.5 659.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 636.5 m 35.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 636.5 m 98.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 636.5 m 180.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 636.5 m 180.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 636.5 m 241.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 636.5 m 241.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 636.5 m 575.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 636.5 m 575.5 636.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 613.5 m 35.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 613.5 m 98.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 613.5 m 180.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 613.5 m 180.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 613.5 m 241.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 613.5 m 241.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 613.5 m 575.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 613.5 m 575.5 613.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 572.5 m 35.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 572.5 m 98.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 572.5 m 180.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 572.5 m 241.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 572.5 m 575.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 572.5 m 575.5 572.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 540.5 m 35.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 508.5 m 98.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 540.5 m 98.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 508.5 m 180.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 540.5 m 180.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 540.5 m 241.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 508.5 m 241.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 540.5 m 241.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 540.5 m 575.5 508.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 540.5 m 575.5 540.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 508.5 m 575.5 508.5 l s BT /F4 9.00 Tf ET q 0 0 0 rg BT 53.25 627.45 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 124.45 691.36 Td (NSCLC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.50 723.36 Td (November) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 714.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 741.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.17 741.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 311.84 741.36 Td (III ) Tj ET Q q 0 0 0 rg BT 323.51 741.36 Td (study ) Tj ET Q q 0 0 0 rg BT 345.69 741.36 Td (Checkmate-078, ) Tj ET Q q 0 0 0 rg BT 407.59 741.36 Td (a ) Tj ET Q q 0 0 0 rg BT 414.26 741.36 Td (multinational, ) Tj ET Q q 0 0 0 rg BT 467.18 741.36 Td (randomized ) Tj ET Q q 0 0 0 rg BT 512.34 741.36 Td (study ) Tj ET Q q 0 0 0 rg BT 534.52 741.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 244.00 732.35 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 270.49 732.35 Td ( ) Tj ET Q q 0 0 0 rg BT 272.62 732.35 Td (versus ) Tj ET Q q 0 0 0 rg BT 297.74 732.35 Td (docetaxel ) Tj ET Q q 0 0 0 rg BT 334.34 732.35 Td (in ) Tj ET Q q 0 0 0 rg BT 343.46 732.35 Td (previously ) Tj ET Q q 0 0 0 rg BT 383.58 732.35 Td (treated ) Tj ET Q q 0 0 0 rg BT 410.18 732.35 Td (advanced ) Tj ET Q q 0 0 0 rg BT 446.28 732.35 Td (or ) Tj ET Q q 0 0 0 rg BT 455.90 732.35 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 494.51 732.35 Td (NSCLC, ) Tj ET Q q 0 0 0 rg BT 527.89 732.35 Td (was ) Tj ET Q q 0 0 0 rg BT 544.01 732.35 Td (stopped ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 723.36 Td (early ) Tj ET Q q 0 0 0 rg BT 269.36 723.36 Td (having ) Tj ET Q q 0 0 0 rg BT 301.22 723.36 Td (met ) Tj ET Q q 0 0 0 rg BT 322.08 723.36 Td (its ) Tj ET Q q 0 0 0 rg BT 337.96 723.36 Td (primary ) Tj ET Q q 0 0 0 rg BT 373.81 723.36 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 412.68 723.36 Td (demonstrating ) Tj ET Q q 0 0 0 rg BT 471.54 723.36 Td (superior ) Tj ET Q q 0 0 0 rg BT 508.40 723.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 540.75 723.36 Td (survival. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 714.36 Td (CheckMate-078 ) Tj ET Q q 0 0 0 rg BT 303.46 714.36 Td (is ) Tj ET Q q 0 0 0 rg BT 310.95 714.36 Td (a ) Tj ET Q q 0 0 0 rg BT 316.42 714.36 Td (multinational ) Tj ET Q q 0 0 0 rg BT 365.90 714.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 388.38 714.36 Td (III ) Tj ET Q q 0 0 0 rg BT 398.85 714.36 Td (study ) Tj ET Q q 0 0 0 rg BT 419.84 714.36 Td (with ) Tj ET Q q 0 0 0 rg BT 437.32 714.36 Td (predominately ) Tj ET Q q 0 0 0 rg BT 490.78 714.36 Td (Chinese ) Tj ET Q q 0 0 0 rg BT 521.26 714.36 Td (patients. ) Tj ET Q q 0 0 0 rg BT 552.99 714.36 Td (BMS ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 705.36 Td (submitted ) Tj ET Q q 0 0 0 rg BT 282.30 705.36 Td (a ) Tj ET Q q 0 0 0 rg BT 289.09 705.36 Td (BLA) Tj ET Q q 0 0 0 rg BT 306.59 705.36 Td ( ) Tj ET Q q 0 0 0 rg BT 309.39 705.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 322.68 705.36 Td (Opdivo ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 351.97 705.36 Td (to ) Tj ET Q q 0 0 0 rg BT 361.77 705.36 Td (the ) Tj ET Q q 0 0 0 rg BT 375.56 705.36 Td (China ) Tj ET Q q 0 0 0 rg BT 399.86 705.36 Td (Food ) Tj ET Q q 0 0 0 rg BT 421.16 705.36 Td (and ) Tj ET Q q 0 0 0 rg BT 436.95 705.36 Td (Drug ) Tj ET Q q 0 0 0 rg BT 457.63 705.36 Td (Administration ) Tj ET Q q 0 0 0 rg BT 514.92 705.36 Td (\(CFDA\) ) Tj ET Q q 0 0 0 rg BT 547.72 705.36 Td (for ) Tj ET Q q 0 0 0 rg BT 561.01 705.36 Td (the ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 696.36 Td (proposed ) Tj ET Q q 0 0 0 rg BT 279.24 696.36 Td (indication ) Tj ET Q q 0 0 0 rg BT 317.49 696.36 Td (of ) Tj ET Q q 0 0 0 rg BT 327.23 696.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 367.48 696.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 394.21 696.36 Td (NSCLC, ) Tj ET Q q 0 0 0 rg BT 427.72 696.36 Td (which ) Tj ET Q q 0 0 0 rg BT 451.96 696.36 Td (has ) Tj ET Q q 0 0 0 rg BT 466.21 696.36 Td (been ) Tj ET Q q 0 0 0 rg BT 485.45 696.36 Td (accepted ) Tj ET Q q 0 0 0 rg BT 519.17 696.36 Td (by ) Tj ET Q q 0 0 0 rg BT 530.42 696.36 Td (the ) Tj ET Q q 0 0 0 rg BT 543.67 696.36 Td (CFDA.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 677.86 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 668.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 682.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.58 682.36 Td (three-year ) Tj ET Q q 0 0 0 rg BT 326.15 682.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 353.23 682.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 384.33 682.36 Td (data ) Tj ET Q q 0 0 0 rg BT 401.41 682.36 Td (from ) Tj ET Q q 0 0 0 rg BT 421.00 682.36 Td (CheckMate-017 ) Tj ET Q q 0 0 0 rg BT 481.08 682.36 Td (and ) Tj ET Q q 0 0 0 rg BT 496.17 682.36 Td (CheckMate-057, ) Tj ET Q q 0 0 0 rg BT 558.50 682.36 Td (two ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 673.36 Td (pivotal ) Tj ET Q q 0 0 0 rg BT 273.16 673.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 298.33 673.36 Td (III ) Tj ET Q q 0 0 0 rg BT 311.48 673.36 Td (randomized ) Tj ET Q q 0 0 0 rg BT 358.13 673.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 387.30 673.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 428.95 673.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 455.44 673.36 Td ( ) Tj ET Q q 0 0 0 rg BT 459.61 673.36 Td (vs. ) Tj ET Q q 0 0 0 rg BT 474.03 673.36 Td (docetaxel ) Tj ET Q q 0 0 0 rg BT 512.67 673.36 Td (in ) Tj ET Q q 0 0 0 rg BT 523.84 673.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 673.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 664.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 284.25 664.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 310.98 664.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 349.71 664.36 Td (NSCLC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 645.86 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 650.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.02 650.36 Td (five-year ) Tj ET Q q 0 0 0 rg BT 321.02 650.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 347.54 650.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 378.06 650.36 Td (data ) Tj ET Q q 0 0 0 rg BT 394.58 650.36 Td (from ) Tj ET Q q 0 0 0 rg BT 413.60 650.36 Td (study ) Tj ET Q q 0 0 0 rg BT 434.63 650.36 Td (CA209-003, ) Tj ET Q q 0 0 0 rg BT 480.91 650.36 Td (a ) Tj ET Q q 0 0 0 rg BT 486.43 650.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 508.96 650.36 Td (I ) Tj ET Q q 0 0 0 rg BT 513.48 650.36 Td (study ) Tj ET Q q 0 0 0 rg BT 534.52 650.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 244.00 641.35 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 270.49 641.35 Td ( ) Tj ET Q q 0 0 0 rg BT 272.74 641.35 Td (in ) Tj ET Q q 0 0 0 rg BT 282.00 641.35 Td (patients ) Tj ET Q q 0 0 0 rg BT 312.24 641.35 Td (with ) Tj ET Q q 0 0 0 rg BT 330.49 641.35 Td (previously ) Tj ET Q q 0 0 0 rg BT 370.73 641.35 Td (treated ) Tj ET Q q 0 0 0 rg BT 397.47 641.35 Td (advanced ) Tj ET Q q 0 0 0 rg BT 433.69 641.35 Td (NSCLC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.95 622.86 Td (RCC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.50 627.36 Td (November) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 618.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 627.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.84 627.36 Td (a ) Tj ET Q q 0 0 0 rg BT 296.19 627.36 Td (three-year ) Tj ET Q q 0 0 0 rg BT 336.01 627.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 364.35 627.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 396.70 627.36 Td (update ) Tj ET Q q 0 0 0 rg BT 424.04 627.36 Td (from ) Tj ET Q q 0 0 0 rg BT 444.88 627.36 Td (CheckMate-025, ) Tj ET Q q 0 0 0 rg BT 508.47 627.36 Td (a ) Tj ET Q q 0 0 0 rg BT 515.81 627.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 540.16 627.36 Td (III ) Tj ET Q q 0 0 0 rg BT 552.51 627.36 Td (study ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 618.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 283.74 618.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 310.23 618.36 Td ( ) Tj ET Q q 0 0 0 rg BT 312.48 618.36 Td (vs. ) Tj ET Q q 0 0 0 rg BT 324.98 618.36 Td (everolimus ) Tj ET Q q 0 0 0 rg BT 367.22 618.36 Td (in ) Tj ET Q q 0 0 0 rg BT 376.47 618.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 416.72 618.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 443.45 618.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 479.68 618.36 Td (RCC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 125.25 558.86 Td (V) Tj ET Q q 0 0 0 rg BT 131.25 558.86 Td (arious) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.85 574.86 Td (July 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 604.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 268.16 604.36 Td (and ) Tj ET Q q 0 0 0 rg BT 286.31 604.36 Td (Clovis ) Tj ET Q q 0 0 0 rg BT 314.97 604.36 Td (Oncology) Tj ET Q q 0 0 0 rg BT 349.88 604.36 Td (, ) Tj ET Q q 0 0 0 rg BT 357.28 604.36 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 376.17 604.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 420.31 604.36 Td (a ) Tj ET Q q 0 0 0 rg BT 429.45 604.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 461.09 604.36 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 513.72 604.36 Td (to ) Tj ET Q q 0 0 0 rg BT 525.88 604.36 Td (evaluate ) Tj ET Q q 0 0 0 rg BT 561.01 604.36 Td (the ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 595.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 291.71 595.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 301.92 595.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 328.41 595.36 Td ( ) Tj ET Q q 0 0 0 rg BT 331.13 595.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 346.84 595.36 Td (Rubraca) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 377.84 595.36 Td (* ) Tj ET Q q 0 0 0 rg BT 385.05 595.36 Td (\(rucaparib\) ) Tj ET Q q 0 0 0 rg BT 427.74 595.36 Td (in ) Tj ET Q q 0 0 0 rg BT 437.46 595.36 Td (pivotal ) Tj ET Q q 0 0 0 rg BT 465.17 595.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 488.88 595.36 Td (III ) Tj ET Q q 0 0 0 rg BT 500.59 595.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 528.30 595.36 Td (in ) Tj ET Q q 0 0 0 rg BT 538.02 595.36 Td (advanced ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 586.36 Td (ovarian ) Tj ET Q q 0 0 0 rg BT 274.03 586.36 Td (cancer ) Tj ET Q q 0 0 0 rg BT 300.56 586.36 Td (and ) Tj ET Q q 0 0 0 rg BT 316.60 586.36 Td (triple-negative ) Tj ET Q q 0 0 0 rg BT 372.12 586.36 Td (breast ) Tj ET Q q 0 0 0 rg BT 396.65 586.36 Td (cancer ) Tj ET Q q 0 0 0 rg BT 423.18 586.36 Td (as ) Tj ET Q q 0 0 0 rg BT 433.72 586.36 Td (well ) Tj ET Q q 0 0 0 rg BT 452.26 586.36 Td (as ) Tj ET Q q 0 0 0 rg BT 462.80 586.36 Td (a ) Tj ET Q q 0 0 0 rg BT 469.84 586.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 493.89 586.36 Td (II ) Tj ET Q q 0 0 0 rg BT 502.93 586.36 Td (study ) Tj ET Q q 0 0 0 rg BT 525.48 586.36 Td (in ) Tj ET Q q 0 0 0 rg BT 535.52 586.36 Td (metastatic ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 577.36 Td (castration-resistant ) Tj ET Q q 0 0 0 rg BT 314.22 577.36 Td (prostate ) Tj ET Q q 0 0 0 rg BT 344.96 577.36 Td (cancer) Tj ET Q q 0 0 0 rg BT 367.94 577.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 563.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.23 563.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 305.74 563.36 Td ( ) Tj ET Q q 0 0 0 rg BT 308.49 563.36 Td (accepted ) Tj ET Q q 0 0 0 rg BT 342.70 563.36 Td (the ) Tj ET Q q 0 0 0 rg BT 356.44 563.36 Td (Company's ) Tj ET Q q 0 0 0 rg BT 399.31 563.36 Td (sBLAs ) Tj ET Q q 0 0 0 rg BT 427.06 563.36 Td (to ) Tj ET Q q 0 0 0 rg BT 436.81 563.36 Td (update ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 463.54 563.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 490.03 563.36 Td ( ) Tj ET Q q 0 0 0 rg BT 492.78 563.36 Td (dosing ) Tj ET Q q 0 0 0 rg BT 519.53 563.36 Td (to ) Tj ET Q q 0 0 0 rg BT 529.27 563.36 Td (include ) Tj ET Q q 0 0 0 rg BT 558.51 563.36 Td (480 ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 554.36 Td (mg ) Tj ET Q q 0 0 0 rg BT 259.34 554.36 Td (infused ) Tj ET Q q 0 0 0 rg BT 289.68 554.36 Td (over ) Tj ET Q q 0 0 0 rg BT 309.51 554.36 Td (30 ) Tj ET Q q 0 0 0 rg BT 322.35 554.36 Td (minutes ) Tj ET Q q 0 0 0 rg BT 354.69 554.36 Td (every ) Tj ET Q q 0 0 0 rg BT 378.52 554.36 Td (four ) Tj ET Q q 0 0 0 rg BT 397.35 554.36 Td (weeks ) Tj ET Q q 0 0 0 rg BT 423.69 554.36 Td (for ) Tj ET Q q 0 0 0 rg BT 438.02 554.36 Td (all ) Tj ET Q q 0 0 0 rg BT 450.86 554.36 Td (currently ) Tj ET Q q 0 0 0 rg BT 487.19 554.36 Td (approved ) Tj ET Q q 0 0 0 rg BT 524.51 554.36 Td (monotherapy ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 545.36 Td (indications. ) Tj ET Q q 0 0 0 rg BT 287.83 545.36 Td (The ) Tj ET Q q 0 0 0 rg BT 304.07 545.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 321.58 545.36 Td ( ) Tj ET Q q 0 0 0 rg BT 323.83 545.36 Td (action ) Tj ET Q q 0 0 0 rg BT 348.07 545.36 Td (date ) Tj ET Q q 0 0 0 rg BT 365.31 545.36 Td (is ) Tj ET Q q 0 0 0 rg BT 373.56 545.36 Td (March ) Tj ET Q q 0 0 0 rg BT 399.30 545.36 Td (5, ) Tj ET Q q 0 0 0 rg BT 408.30 545.36 Td (2018.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 522.36 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 531.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 264.98 531.36 Td (and ) Tj ET Q q 0 0 0 rg BT 279.93 531.36 Td (Incyte ) Tj ET Q q 0 0 0 rg BT 304.39 531.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 345.33 531.36 Td (the ) Tj ET Q q 0 0 0 rg BT 358.29 531.36 Td (companies ) Tj ET Q q 0 0 0 rg BT 398.74 531.36 Td (will ) Tj ET Q q 0 0 0 rg BT 414.71 531.36 Td (advance ) Tj ET Q q 0 0 0 rg BT 446.15 531.36 Td (their ) Tj ET Q q 0 0 0 rg BT 464.61 531.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 493.06 531.36 Td (development ) Tj ET Q q 0 0 0 rg BT 541.51 531.36 Td (program ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 522.36 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 283.78 522.36 Td (the ) Tj ET Q q 0 0 0 rg BT 297.08 522.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 344.37 522.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 354.17 522.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 380.66 522.36 Td ( ) Tj ET Q q 0 0 0 rg BT 382.96 522.36 Td (with ) Tj ET Q q 0 0 0 rg BT 401.26 522.36 Td (epacadostat ) Tj ET Q q 0 0 0 rg BT 445.54 522.36 Td (into ) Tj ET Q q 0 0 0 rg BT 461.84 522.36 Td (a ) Tj ET Q q 0 0 0 rg BT 468.13 522.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 491.43 522.36 Td (III ) Tj ET Q q 0 0 0 rg BT 502.72 522.36 Td (registrational ) Tj ET Q q 0 0 0 rg BT 552.50 522.36 Td (study ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 513.36 Td (in ) Tj ET Q q 0 0 0 rg BT 253.25 513.36 Td (first-line ) Tj ET Q q 0 0 0 rg BT 286.49 513.36 Td (NSCLC ) Tj ET Q q 0 0 0 rg BT 317.75 513.36 Td (across ) Tj ET Q q 0 0 0 rg BT 342.49 513.36 Td (the ) Tj ET Q q 0 0 0 rg BT 355.74 513.36 Td (spectrum ) Tj ET Q q 0 0 0 rg BT 390.98 513.36 Td (of ) Tj ET Q q 0 0 0 rg BT 400.72 513.36 Td (PD-L1 ) Tj ET Q q 0 0 0 rg BT 427.47 513.36 Td (expression ) Tj ET Q q 0 0 0 rg BT 468.21 513.36 Td (and ) Tj ET Q q 0 0 0 rg BT 483.46 513.36 Td (first-line ) Tj ET Q q 0 0 0 rg BT 516.70 513.36 Td (HNC.) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 498.5 m 35.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 498.5 m 98.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 498.5 m 98.5 498.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 498.5 m 180.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 498.5 m 180.5 498.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 498.5 m 241.5 498.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 498.5 m 241.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 498.5 m 575.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 498.5 m 575.5 498.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 466.5 m 35.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 466.5 m 98.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 466.5 m 180.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 466.5 m 180.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 466.5 m 241.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 466.5 m 241.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 466.5 m 575.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 466.5 m 575.5 466.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 443.5 m 35.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 443.5 m 98.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 443.5 m 180.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 443.5 m 241.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 443.5 m 241.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 443.5 m 575.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 443.5 m 575.5 443.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 411.5 m 35.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 411.5 m 98.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 411.5 m 180.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 411.5 m 180.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 411.5 m 241.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 411.5 m 241.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 411.5 m 575.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 411.5 m 575.5 411.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 388.5 m 35.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 388.5 m 98.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 388.5 m 98.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 388.5 m 180.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 388.5 m 180.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 338.5 m 180.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 388.5 m 180.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 388.5 m 241.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 388.5 m 241.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 338.5 m 241.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 388.5 m 241.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 388.5 m 575.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 388.5 m 575.5 388.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 338.5 m 575.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 338.5 m 35.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 338.5 m 98.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 338.5 m 180.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 338.5 m 180.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 338.5 m 241.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 338.5 m 241.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 338.5 m 575.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 338.5 m 575.5 338.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 279.5 m 35.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 279.5 m 98.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 279.5 m 180.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 279.5 m 180.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 279.5 m 241.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 279.5 m 241.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 247.5 m 241.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 279.5 m 241.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 279.5 m 575.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 279.5 m 575.5 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 247.5 m 35.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 247.5 m 98.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 247.5 m 180.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 247.5 m 241.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 247.5 m 241.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 247.5 m 575.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 247.5 m 575.5 247.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 188.5 m 35.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 188.5 m 98.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 188.5 m 180.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 188.5 m 241.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 188.5 m 241.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 188.5 m 575.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 188.5 m 575.5 188.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 156.5 m 35.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 156.5 m 98.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 156.5 m 180.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 156.5 m 241.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 156.5 m 241.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 156.5 m 575.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 156.5 m 575.5 156.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 115.5 m 35.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 115.5 m 98.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 115.5 m 180.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 115.5 m 180.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 83.5 m 180.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 115.5 m 241.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 115.5 m 241.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 115.5 m 575.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 115.5 m 575.5 115.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 83.5 m 35.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 83.5 m 98.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 42.5 m 98.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 83.5 m 180.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 42.5 m 180.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 83.5 m 241.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 42.5 m 241.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 83.5 m 241.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 83.5 m 575.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 83.5 m 575.5 83.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 42.5 m 575.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 42.5 m 98.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 42.5 m 241.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 42.5 m 575.5 42.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 38 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 38 m BT /F4 9.00 Tf ET q 0 0 0 rg BT 38.40 268.45 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 74.52 268.45 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.95 480.36 Td (CRC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 186.35 480.36 Td (January 2018) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 489.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.02 489.36 Td (new ) Tj ET Q q 0 0 0 rg BT 303.55 489.36 Td (data ) Tj ET Q q 0 0 0 rg BT 320.07 489.36 Td (from ) Tj ET Q q 0 0 0 rg BT 339.09 489.36 Td (CheckMate-142, ) Tj ET Q q 0 0 0 rg BT 400.86 489.36 Td (a ) Tj ET Q q 0 0 0 rg BT 406.38 489.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 428.91 489.36 Td (II ) Tj ET Q q 0 0 0 rg BT 436.44 489.36 Td (study ) Tj ET Q q 0 0 0 rg BT 457.47 489.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 496.49 489.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 522.98 489.36 Td ( ) Tj ET Q q 0 0 0 rg BT 524.52 489.36 Td (monotherapy ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 480.36 Td (or ) Tj ET Q q 0 0 0 rg BT 252.68 480.36 Td (in ) Tj ET Q q 0 0 0 rg BT 260.87 480.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 307.04 480.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 324.23 480.36 Td (Y) Tj ET Q q 0 0 0 rg BT 328.41 480.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 348.39 480.36 Td ( ) Tj ET Q q 0 0 0 rg BT 349.58 480.36 Td (for ) Tj ET Q q 0 0 0 rg BT 361.26 480.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 400.44 480.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 426.10 480.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 455.28 480.36 Td (with ) Tj ET Q q 0 0 0 rg BT 472.47 480.36 Td (dMMR ) Tj ET Q q 0 0 0 rg BT 500.16 480.36 Td (or ) Tj ET Q q 0 0 0 rg BT 508.84 480.36 Td (MSI-H ) Tj ET Q q 0 0 0 rg BT 535.53 480.36 Td (metastatic ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 471.36 Td (CRC. ) Tj ET Q q 0 0 0 rg BT 266.51 471.36 Td (Interim ) Tj ET Q q 0 0 0 rg BT 295.25 471.36 Td (data ) Tj ET Q q 0 0 0 rg BT 312.49 471.36 Td (had ) Tj ET Q q 0 0 0 rg BT 327.73 471.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 367.98 471.36 Td (been ) Tj ET Q q 0 0 0 rg BT 387.22 471.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 428.45 471.36 Td (in ) Tj ET Q q 0 0 0 rg BT 437.70 471.36 Td (June ) Tj ET Q q 0 0 0 rg BT 456.45 471.36 Td (2017.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 119.75 436.86 Td (Melanoma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 452.86 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 457.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.52 457.36 Td (ef) Tj ET Q q 0 0 0 rg BT 294.35 457.36 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 318.36 457.36 Td (data ) Tj ET Q q 0 0 0 rg BT 335.37 457.36 Td (from ) Tj ET Q q 0 0 0 rg BT 354.90 457.36 Td (CheckMate-204, ) Tj ET Q q 0 0 0 rg BT 417.16 457.36 Td (a ) Tj ET Q q 0 0 0 rg BT 423.18 457.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 446.21 457.36 Td (II ) Tj ET Q q 0 0 0 rg BT 454.23 457.36 Td (study ) Tj ET Q q 0 0 0 rg BT 475.76 457.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 515.27 457.36 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 552.02 457.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 572.01 457.36 Td ( ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 448.36 Td (as ) Tj ET Q q 0 0 0 rg BT 253.75 448.36 Td (a ) Tj ET Q q 0 0 0 rg BT 259.99 448.36 Td (potential ) Tj ET Q q 0 0 0 rg BT 293.73 448.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 329.97 448.36 Td (for ) Tj ET Q q 0 0 0 rg BT 342.71 448.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 372.95 448.36 Td (with ) Tj ET Q q 0 0 0 rg BT 391.20 448.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 430.94 448.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 469.67 448.36 Td (to ) Tj ET Q q 0 0 0 rg BT 478.92 448.36 Td (the ) Tj ET Q q 0 0 0 rg BT 492.17 448.36 Td (brain.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 425.36 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 434.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.52 434.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 314.54 434.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 345.56 434.36 Td (data ) Tj ET Q q 0 0 0 rg BT 362.59 434.36 Td (from ) Tj ET Q q 0 0 0 rg BT 382.11 434.36 Td (CheckMate-067, ) Tj ET Q q 0 0 0 rg BT 444.37 434.36 Td (a ) Tj ET Q q 0 0 0 rg BT 450.40 434.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 473.43 434.36 Td (III ) Tj ET Q q 0 0 0 rg BT 484.45 434.36 Td (study ) Tj ET Q q 0 0 0 rg BT 505.99 434.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 545.50 434.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 572.00 434.36 Td ( ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 425.36 Td (alone ) Tj ET Q q 0 0 0 rg BT 268.25 425.36 Td (or ) Tj ET Q q 0 0 0 rg BT 280.52 425.36 Td (in ) Tj ET Q q 0 0 0 rg BT 292.28 425.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 342.04 425.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 362.80 425.36 Td (Y) Tj ET Q q 0 0 0 rg BT 366.98 425.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 386.97 425.36 Td ( ) Tj ET Q q 0 0 0 rg BT 391.73 425.36 Td (in ) Tj ET Q q 0 0 0 rg BT 403.49 425.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 436.25 425.36 Td (with ) Tj ET Q q 0 0 0 rg BT 457.02 425.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 499.78 425.36 Td (untreated ) Tj ET Q q 0 0 0 rg BT 538.02 425.36 Td (advanced ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 416.36 Td (melanoma.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 128.45 397.86 Td (MPM) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 397.86 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 402.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 290.03 402.36 Td (results ) Tj ET Q q 0 0 0 rg BT 318.06 402.36 Td (from ) Tj ET Q q 0 0 0 rg BT 340.09 402.36 Td (the ) Tj ET Q q 0 0 0 rg BT 355.62 402.36 Td (IFCT) Tj ET Q q 0 0 0 rg BT 374.30 402.36 Td (-1501 ) Tj ET Q q 0 0 0 rg BT 399.83 402.36 Td (MAPS-2 ) Tj ET Q q 0 0 0 rg BT 436.38 402.36 Td (study ) Tj ET Q q 0 0 0 rg BT 460.42 402.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 502.44 402.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 528.94 402.36 Td ( ) Tj ET Q q 0 0 0 rg BT 533.47 402.36 Td (or ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 545.51 402.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 572.00 402.36 Td ( ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 393.36 Td (combined ) Tj ET Q q 0 0 0 rg BT 281.74 393.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 299.99 393.36 Td (Y) Tj ET Q q 0 0 0 rg BT 304.17 393.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 324.16 393.36 Td ( ) Tj ET Q q 0 0 0 rg BT 326.41 393.36 Td (for ) Tj ET Q q 0 0 0 rg BT 339.15 393.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 379.40 393.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 406.13 393.36 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 453.35 393.36 Td (MPM ) Tj ET Q q 0 0 0 rg BT 476.61 393.36 Td (patients.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 124.45 361.36 Td (NSCLC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 184.10 361.36 Td (February 2018) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 379.76 Td (Announced ) Tj ET Q q 0 0 0 rg BT 291.22 379.76 Td (that ) Tj ET Q q 0 0 0 rg BT 310.45 379.76 Td (the ) Tj ET Q q 0 0 0 rg BT 327.17 379.76 Td (pivotal ) Tj ET Q q 0 0 0 rg BT 357.90 379.76 Td (Phase ) Tj ET Q q 0 0 0 rg BT 384.63 379.76 Td (III ) Tj ET Q q 0 0 0 rg BT 399.35 379.76 Td (CheckMate-227 ) Tj ET Q q 0 0 0 rg BT 463.06 379.76 Td (study ) Tj ET Q q 0 0 0 rg BT 488.29 379.76 Td (demonstrated ) Tj ET Q q 0 0 0 rg BT 542.51 379.76 Td (superior ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 370.76 Td (progression-free ) Tj ET Q q 0 0 0 rg BT 305.62 370.76 Td (survival ) Tj ET Q q 0 0 0 rg BT 337.27 370.76 Td (with ) Tj ET Q q 0 0 0 rg BT 355.92 370.76 Td (the ) Tj ET Q q 0 0 0 rg BT 369.56 370.76 Td (combination ) Tj ET Q q 0 0 0 rg BT 417.20 370.76 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 427.35 370.76 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 453.84 370.76 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 458.92 370.76 Td (Y) Tj ET Q q 0 0 0 rg BT 463.10 370.76 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 483.08 370.76 Td ( ) Tj ET Q q 0 0 0 rg BT 485.73 370.76 Td (versus ) Tj ET Q q 0 0 0 rg BT 511.38 370.76 Td (chemotherapy ) Tj ET Q q 0 0 0 rg BT 565.00 370.76 Td (in ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 361.76 Td (first-line ) Tj ET Q q 0 0 0 rg BT 276.63 361.76 Td (NSCLC ) Tj ET Q q 0 0 0 rg BT 307.28 361.76 Td (patients ) Tj ET Q q 0 0 0 rg BT 336.92 361.76 Td (with ) Tj ET Q q 0 0 0 rg BT 354.56 361.76 Td (high ) Tj ET Q q 0 0 0 rg BT 372.20 361.76 Td (tumor ) Tj ET Q q 0 0 0 rg BT 395.34 361.76 Td (mutation ) Tj ET Q q 0 0 0 rg BT 428.98 361.76 Td (burden, ) Tj ET Q q 0 0 0 rg BT 457.86 361.76 Td (regardless ) Tj ET Q q 0 0 0 rg BT 495.99 361.76 Td (of ) Tj ET Q q 0 0 0 rg BT 505.13 361.76 Td (PD-L1 ) Tj ET Q q 0 0 0 rg BT 531.27 361.76 Td (expression. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 352.76 Td (The ) Tj ET Q q 0 0 0 rg BT 261.06 352.76 Td (study ) Tj ET Q q 0 0 0 rg BT 283.62 352.76 Td (will ) Tj ET Q q 0 0 0 rg BT 300.69 352.76 Td (continue ) Tj ET Q q 0 0 0 rg BT 334.74 352.76 Td (as ) Tj ET Q q 0 0 0 rg BT 345.30 352.76 Td (planned ) Tj ET Q q 0 0 0 rg BT 376.86 352.76 Td (to ) Tj ET Q q 0 0 0 rg BT 386.92 352.76 Td (assess ) Tj ET Q q 0 0 0 rg BT 411.98 352.76 Td (the ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 426.04 352.76 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 452.54 352.76 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 457.61 352.76 Td (Y) Tj ET Q q 0 0 0 rg BT 461.79 352.76 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 481.78 352.76 Td ( ) Tj ET Q q 0 0 0 rg BT 484.84 352.76 Td (combination ) Tj ET Q q 0 0 0 rg BT 532.90 352.76 Td (for ) Tj ET Q q 0 0 0 rg BT 546.46 352.76 Td (the ) Tj ET Q q 0 0 0 rg BT 560.52 352.76 Td (co-) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 343.76 Td (primary ) Tj ET Q q 0 0 0 rg BT 274.74 343.76 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 308.49 343.76 Td (of ) Tj ET Q q 0 0 0 rg BT 318.23 343.76 Td (overall ) Tj ET Q q 0 0 0 rg BT 345.47 343.76 Td (survival ) Tj ET Q q 0 0 0 rg BT 376.71 343.76 Td (in ) Tj ET Q q 0 0 0 rg BT 385.97 343.76 Td (patients ) Tj ET Q q 0 0 0 rg BT 416.21 343.76 Td (who ) Tj ET Q q 0 0 0 rg BT 433.96 343.76 Td (express ) Tj ET Q q 0 0 0 rg BT 463.20 343.76 Td (PD-L1. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.95 224.86 Td (RCC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.00 311.36 Td (December) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 302.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 329.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.00 329.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 305.50 329.36 Td ( ) Tj ET Q q 0 0 0 rg BT 308.01 329.36 Td (accepted ) Tj ET Q q 0 0 0 rg BT 341.99 329.36 Td (the ) Tj ET Q q 0 0 0 rg BT 355.49 329.36 Td (Company's ) Tj ET Q q 0 0 0 rg BT 398.12 329.36 Td (sBLA's ) Tj ET Q q 0 0 0 rg BT 427.26 329.36 Td (for ) Tj ET Q q 0 0 0 rg BT 440.26 329.36 Td (priority ) Tj ET Q q 0 0 0 rg BT 469.76 329.36 Td (review ) Tj ET Q q 0 0 0 rg BT 496.76 329.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 506.76 329.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 533.25 329.36 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 538.33 329.36 Td (Y) Tj ET Q q 0 0 0 rg BT 542.51 329.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 562.50 329.36 Td ( ) Tj ET Q q 0 0 0 rg BT 565.00 329.36 Td (to ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 320.36 Td (treat ) Tj ET Q q 0 0 0 rg BT 262.31 320.36 Td (intermediate ) Tj ET Q q 0 0 0 rg BT 309.61 320.36 Td (and ) Tj ET Q q 0 0 0 rg BT 324.93 320.36 Td (poor) Tj ET Q q 0 0 0 rg BT 341.25 320.36 Td (-risk ) Tj ET Q q 0 0 0 rg BT 360.06 320.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 390.38 320.36 Td (with ) Tj ET Q q 0 0 0 rg BT 408.70 320.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 445.01 320.36 Td (RCC. ) Tj ET Q q 0 0 0 rg BT 467.42 320.36 Td (The ) Tj ET Q q 0 0 0 rg BT 483.73 320.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 501.24 320.36 Td ( ) Tj ET Q q 0 0 0 rg BT 503.56 320.36 Td (action ) Tj ET Q q 0 0 0 rg BT 527.88 320.36 Td (date ) Tj ET Q q 0 0 0 rg BT 545.19 320.36 Td (is ) Tj ET Q q 0 0 0 rg BT 553.00 320.36 Td (April ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 311.36 Td (16, ) Tj ET Q q 0 0 0 rg BT 259.22 311.36 Td (2018. ) Tj ET Q q 0 0 0 rg BT 283.45 311.36 Td (In ) Tj ET Q q 0 0 0 rg BT 294.92 311.36 Td (November) Tj ET Q q 0 0 0 rg BT 332.54 311.36 Td (, ) Tj ET Q q 0 0 0 rg BT 338.77 311.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 381.73 311.36 Td (results ) Tj ET Q q 0 0 0 rg BT 409.20 311.36 Td (from ) Tj ET Q q 0 0 0 rg BT 430.66 311.36 Td (a ) Tj ET Q q 0 0 0 rg BT 438.63 311.36 Td (new ) Tj ET Q q 0 0 0 rg BT 457.60 311.36 Td (exploratory ) Tj ET Q q 0 0 0 rg BT 503.06 311.36 Td (analysis ) Tj ET Q q 0 0 0 rg BT 536.03 311.36 Td (of ) Tj ET Q q 0 0 0 rg BT 547.50 311.36 Td (PD-L1 ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 302.36 Td (expression ) Tj ET Q q 0 0 0 rg BT 284.75 302.36 Td (subgroups ) Tj ET Q q 0 0 0 rg BT 324.01 302.36 Td (of ) Tj ET Q q 0 0 0 rg BT 333.76 302.36 Td (the ) Tj ET Q q 0 0 0 rg BT 347.01 302.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 370.27 302.36 Td (III ) Tj ET Q q 0 0 0 rg BT 381.52 302.36 Td (CheckMate-214 ) Tj ET Q q 0 0 0 rg BT 441.75 302.36 Td (study ) Tj ET Q q 0 0 0 rg BT 463.51 302.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 503.26 302.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 529.75 302.36 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 534.83 302.36 Td (Y) Tj ET Q q 0 0 0 rg BT 539.00 302.36 Td (ervo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.00 302.36 Td (y ) Tj ET Q q 0 0 0 rg BT 561.75 302.36 Td (vs. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 293.36 Td (the ) Tj ET Q q 0 0 0 rg BT 259.11 293.36 Td (standard ) Tj ET Q q 0 0 0 rg BT 293.71 293.36 Td (of ) Tj ET Q q 0 0 0 rg BT 305.33 293.36 Td (care, ) Tj ET Q q 0 0 0 rg BT 326.67 293.36 Td (sunitinib, ) Tj ET Q q 0 0 0 rg BT 364.54 293.36 Td (in ) Tj ET Q q 0 0 0 rg BT 375.66 293.36 Td (intermediate- ) Tj ET Q q 0 0 0 rg BT 427.75 293.36 Td (and ) Tj ET Q q 0 0 0 rg BT 444.85 293.36 Td (poor) Tj ET Q q 0 0 0 rg BT 461.17 293.36 Td (-risk ) Tj ET Q q 0 0 0 rg BT 481.78 293.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 513.89 293.36 Td (with ) Tj ET Q q 0 0 0 rg BT 534.01 293.36 Td (previously ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 284.36 Td (untreated ) Tj ET Q q 0 0 0 rg BT 279.73 284.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 315.96 284.36 Td (or ) Tj ET Q q 0 0 0 rg BT 325.71 284.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 364.44 284.36 Td (RCC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.50 265.86 Td (November) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 256.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 270.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.05 270.36 Td (the ) Tj ET Q q 0 0 0 rg BT 301.61 270.36 Td (EMA) Tj ET Q q 0 0 0 rg BT 321.12 270.36 Td ( ) Tj ET Q q 0 0 0 rg BT 323.68 270.36 Td (validated ) Tj ET Q q 0 0 0 rg BT 359.23 270.36 Td (its ) Tj ET Q q 0 0 0 rg BT 370.30 270.36 Td (type ) Tj ET Q q 0 0 0 rg BT 388.36 270.36 Td (II ) Tj ET Q q 0 0 0 rg BT 396.92 270.36 Td (variation ) Tj ET Q q 0 0 0 rg BT 431.47 270.36 Td (application, ) Tj ET Q q 0 0 0 rg BT 476.27 270.36 Td (which ) Tj ET Q q 0 0 0 rg BT 500.83 270.36 Td (seeks ) Tj ET Q q 0 0 0 rg BT 522.89 270.36 Td (to ) Tj ET Q q 0 0 0 rg BT 532.45 270.36 Td (expand ) Tj ET Q q 0 0 0 rg BT 561.00 270.36 Td (the ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 261.36 Td (current ) Tj ET Q q 0 0 0 rg BT 272.17 261.36 Td (indications ) Tj ET Q q 0 0 0 rg BT 314.35 261.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 327.53 261.36 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 364.28 261.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 384.26 261.36 Td ( ) Tj ET Q q 0 0 0 rg BT 386.95 261.36 Td (to ) Tj ET Q q 0 0 0 rg BT 396.64 261.36 Td (include ) Tj ET Q q 0 0 0 rg BT 425.81 261.36 Td (the ) Tj ET Q q 0 0 0 rg BT 439.49 261.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 476.16 261.36 Td (of ) Tj ET Q q 0 0 0 rg BT 486.35 261.36 Td (intermediate- ) Tj ET Q q 0 0 0 rg BT 537.01 261.36 Td (and ) Tj ET Q q 0 0 0 rg BT 552.69 261.36 Td (poor) Tj ET Q q 0 0 0 rg BT 569.00 261.36 Td (-) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 252.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 259.75 252.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 289.99 252.36 Td (with ) Tj ET Q q 0 0 0 rg BT 308.24 252.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 344.47 252.36 Td (RCC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 220.36 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 211.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 238.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.30 238.36 Td (CheckMate-214, ) Tj ET Q q 0 0 0 rg BT 349.33 238.36 Td (a ) Tj ET Q q 0 0 0 rg BT 355.14 238.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 377.94 238.36 Td (III ) Tj ET Q q 0 0 0 rg BT 388.74 238.36 Td (study ) Tj ET Q q 0 0 0 rg BT 410.05 238.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 449.34 238.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 475.84 238.36 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 480.91 238.36 Td (Y) Tj ET Q q 0 0 0 rg BT 485.09 238.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 505.08 238.36 Td ( ) Tj ET Q q 0 0 0 rg BT 506.88 238.36 Td (versus ) Tj ET Q q 0 0 0 rg BT 531.69 238.36 Td (sunitinib ) Tj ET Q q 0 0 0 rg BT 565.00 238.36 Td (in ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 229.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 273.68 229.36 Td (with ) Tj ET Q q 0 0 0 rg BT 291.37 229.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 331.06 229.36 Td (untreated ) Tj ET Q q 0 0 0 rg BT 366.23 229.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 401.90 229.36 Td (or ) Tj ET Q q 0 0 0 rg BT 411.09 229.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 449.26 229.36 Td (RCC, ) Tj ET Q q 0 0 0 rg BT 471.21 229.36 Td (met ) Tj ET Q q 0 0 0 rg BT 486.39 229.36 Td (its ) Tj ET Q q 0 0 0 rg BT 496.59 229.36 Td (co-primary ) Tj ET Q q 0 0 0 rg BT 538.26 229.36 Td (endpoint, ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 220.36 Td (demonstrating ) Tj ET Q q 0 0 0 rg BT 300.87 220.36 Td (superior ) Tj ET Q q 0 0 0 rg BT 335.74 220.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 366.10 220.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 400.48 220.36 Td (in ) Tj ET Q q 0 0 0 rg BT 412.86 220.36 Td (intermediate- ) Tj ET Q q 0 0 0 rg BT 466.21 220.36 Td (and ) Tj ET Q q 0 0 0 rg BT 484.58 220.36 Td (poor) Tj ET Q q 0 0 0 rg BT 500.90 220.36 Td (-risk ) Tj ET Q q 0 0 0 rg BT 522.78 220.36 Td (patients. ) Tj ET Q q 0 0 0 rg BT 558.01 220.36 Td (The ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 211.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 291.37 211.36 Td (also ) Tj ET Q q 0 0 0 rg BT 308.25 211.36 Td (met ) Tj ET Q q 0 0 0 rg BT 324.13 211.36 Td (a ) Tj ET Q q 0 0 0 rg BT 330.51 211.36 Td (secondary ) Tj ET Q q 0 0 0 rg BT 369.38 211.36 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 403.25 211.36 Td (of ) Tj ET Q q 0 0 0 rg BT 413.13 211.36 Td (improved ) Tj ET Q q 0 0 0 rg BT 450.01 211.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 477.38 211.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 508.76 211.36 Td (in ) Tj ET Q q 0 0 0 rg BT 518.14 211.36 Td (all ) Tj ET Q q 0 0 0 rg BT 529.52 211.36 Td (randomized ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 202.36 Td (patients. ) Tj ET Q q 0 0 0 rg BT 276.66 202.36 Td (Based ) Tj ET Q q 0 0 0 rg BT 301.07 202.36 Td (on ) Tj ET Q q 0 0 0 rg BT 312.49 202.36 Td (a ) Tj ET Q q 0 0 0 rg BT 318.90 202.36 Td (planned ) Tj ET Q q 0 0 0 rg BT 349.80 202.36 Td (interim ) Tj ET Q q 0 0 0 rg BT 378.21 202.36 Td (analysis, ) Tj ET Q q 0 0 0 rg BT 411.87 202.36 Td (an ) Tj ET Q q 0 0 0 rg BT 422.78 202.36 Td (independent ) Tj ET Q q 0 0 0 rg BT 469.18 202.36 Td (Data ) Tj ET Q q 0 0 0 rg BT 488.59 202.36 Td (Monitoring ) Tj ET Q q 0 0 0 rg BT 532.01 202.36 Td (Committee ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 193.36 Td (has ) Tj ET Q q 0 0 0 rg BT 258.25 193.36 Td (recommended ) Tj ET Q q 0 0 0 rg BT 311.47 193.36 Td (that ) Tj ET Q q 0 0 0 rg BT 327.22 193.36 Td (the ) Tj ET Q q 0 0 0 rg BT 340.46 193.36 Td (study ) Tj ET Q q 0 0 0 rg BT 362.22 193.36 Td (be ) Tj ET Q q 0 0 0 rg BT 372.96 193.36 Td (stopped ) Tj ET Q q 0 0 0 rg BT 403.21 193.36 Td (early) Tj ET Q q 0 0 0 rg BT 420.61 193.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 187.35 170.36 Td (August 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 179.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.13 179.36 Td (topline ) Tj ET Q q 0 0 0 rg BT 315.77 179.36 Td (results ) Tj ET Q q 0 0 0 rg BT 341.91 179.36 Td (from ) Tj ET Q q 0 0 0 rg BT 362.05 179.36 Td (CheckMate-214. ) Tj ET Q q 0 0 0 rg BT 424.73 179.36 Td (The ) Tj ET Q q 0 0 0 rg BT 441.36 179.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 489.00 179.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 499.13 179.36 Td (Opdivo+Y) Tj ET Q q 0 0 0 rg BT 535.88 179.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 555.87 179.36 Td ( ) Tj ET Q q 0 0 0 rg BT 558.51 179.36 Td (met ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 170.36 Td (the ) Tj ET Q q 0 0 0 rg BT 256.24 170.36 Td (co-primary ) Tj ET Q q 0 0 0 rg BT 297.46 170.36 Td (endpoint ) Tj ET Q q 0 0 0 rg BT 330.19 170.36 Td (of ) Tj ET Q q 0 0 0 rg BT 338.93 170.36 Td (objective ) Tj ET Q q 0 0 0 rg BT 373.16 170.36 Td (response ) Tj ET Q q 0 0 0 rg BT 405.89 170.36 Td (rate ) Tj ET Q q 0 0 0 rg BT 420.61 170.36 Td (and ) Tj ET Q q 0 0 0 rg BT 434.85 170.36 Td (was ) Tj ET Q q 0 0 0 rg BT 450.09 170.36 Td (favored ) Tj ET Q q 0 0 0 rg BT 478.81 170.36 Td (in ) Tj ET Q q 0 0 0 rg BT 487.05 170.36 Td (the ) Tj ET Q q 0 0 0 rg BT 499.29 170.36 Td (co-primary ) Tj ET Q q 0 0 0 rg BT 540.51 170.36 Td (endpoint ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 161.36 Td (of ) Tj ET Q q 0 0 0 rg BT 253.75 161.36 Td (progression-free ) Tj ET Q q 0 0 0 rg BT 314.97 161.36 Td (survival, ) Tj ET Q q 0 0 0 rg BT 348.47 161.36 Td (however) Tj ET Q q 0 0 0 rg BT 379.09 161.36 Td (, ) Tj ET Q q 0 0 0 rg BT 383.59 161.36 Td (it ) Tj ET Q q 0 0 0 rg BT 390.84 161.36 Td (did ) Tj ET Q q 0 0 0 rg BT 404.59 161.36 Td (not ) Tj ET Q q 0 0 0 rg BT 418.34 161.36 Td (reach ) Tj ET Q q 0 0 0 rg BT 440.08 161.36 Td (statistical ) Tj ET Q q 0 0 0 rg BT 476.32 161.36 Td (significance. ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.85 133.86 Td (July 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 147.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 265.55 147.36 Td (and ) Tj ET Q q 0 0 0 rg BT 281.09 147.36 Td (Exelixis, ) Tj ET Q q 0 0 0 rg BT 315.37 147.36 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 331.65 147.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 373.18 147.36 Td (the ) Tj ET Q q 0 0 0 rg BT 386.71 147.36 Td (initiation ) Tj ET Q q 0 0 0 rg BT 421.75 147.36 Td (of ) Tj ET Q q 0 0 0 rg BT 431.79 147.36 Td (the ) Tj ET Q q 0 0 0 rg BT 445.32 147.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 468.86 147.36 Td (III ) Tj ET Q q 0 0 0 rg BT 480.39 147.36 Td (CheckMate ) Tj ET Q q 0 0 0 rg BT 524.42 147.36 Td (9ER ) Tj ET Q q 0 0 0 rg BT 542.96 147.36 Td (study ) Tj ET Q q 0 0 0 rg BT 565.00 147.36 Td (to ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 138.36 Td (evaluate ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 275.89 138.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 302.39 138.36 Td ( ) Tj ET Q q 0 0 0 rg BT 304.30 138.36 Td (in ) Tj ET Q q 0 0 0 rg BT 313.22 138.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 360.12 138.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 378.04 138.36 Td (Cabometyx) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 418.52 138.36 Td (* ) Tj ET Q q 0 0 0 rg BT 424.94 138.36 Td (\(cabozantinib\), ) Tj ET Q q 0 0 0 rg BT 481.08 138.36 Td (Exelixis's ) Tj ET Q q 0 0 0 rg BT 517.61 138.36 Td (small ) Tj ET Q q 0 0 0 rg BT 539.02 138.36 Td (molecule ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 129.36 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 276.51 129.36 Td (of ) Tj ET Q q 0 0 0 rg BT 285.52 129.36 Td (receptor ) Tj ET Q q 0 0 0 rg BT 316.51 129.36 Td (tyrosine ) Tj ET Q q 0 0 0 rg BT 347.02 129.36 Td (kinases, ) Tj ET Q q 0 0 0 rg BT 377.28 129.36 Td (or ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 386.29 129.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 412.78 129.36 Td ( ) Tj ET Q q 0 0 0 rg BT 414.29 129.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 428.80 129.36 Td (Y) Tj ET Q q 0 0 0 rg BT 432.98 129.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 452.97 129.36 Td ( ) Tj ET Q q 0 0 0 rg BT 454.48 129.36 Td (in ) Tj ET Q q 0 0 0 rg BT 462.99 129.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 509.50 129.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 527.01 129.36 Td (Cabometyx) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 567.50 129.36 Td (* ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 120.36 Td (versus ) Tj ET Q q 0 0 0 rg BT 269.25 120.36 Td (sunitinib ) Tj ET Q q 0 0 0 rg BT 303.00 120.36 Td (in ) Tj ET Q q 0 0 0 rg BT 312.25 120.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 342.49 120.36 Td (with ) Tj ET Q q 0 0 0 rg BT 360.75 120.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 400.99 120.36 Td (untreated, ) Tj ET Q q 0 0 0 rg BT 438.97 120.36 Td (advanced ) Tj ET Q q 0 0 0 rg BT 475.20 120.36 Td (or ) Tj ET Q q 0 0 0 rg BT 484.95 120.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 523.68 120.36 Td (RCC.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 127.70 97.36 Td (SCLC) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 185.85 97.36 Td (October 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 106.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.37 106.36 Td (data ) Tj ET Q q 0 0 0 rg BT 304.25 106.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 343.61 106.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 370.11 106.36 Td ( ) Tj ET Q q 0 0 0 rg BT 371.99 106.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 386.87 106.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 413.36 106.36 Td (+) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 418.44 106.36 Td (Y) Tj ET Q q 0 0 0 rg BT 422.62 106.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 442.61 106.36 Td ( ) Tj ET Q q 0 0 0 rg BT 444.49 106.36 Td (in ) Tj ET Q q 0 0 0 rg BT 453.37 106.36 Td (previously ) Tj ET Q q 0 0 0 rg BT 493.25 106.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 519.62 106.36 Td (SCLC ) Tj ET Q q 0 0 0 rg BT 544.01 106.36 Td (patients ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 97.36 Td (whose ) Tj ET Q q 0 0 0 rg BT 268.67 97.36 Td (tumors ) Tj ET Q q 0 0 0 rg BT 295.35 97.36 Td (were ) Tj ET Q q 0 0 0 rg BT 314.51 97.36 Td (evaluable ) Tj ET Q q 0 0 0 rg BT 350.66 97.36 Td (for ) Tj ET Q q 0 0 0 rg BT 362.83 97.36 Td (tumor ) Tj ET Q q 0 0 0 rg BT 386.01 97.36 Td (mutation ) Tj ET Q q 0 0 0 rg BT 419.68 97.36 Td (burden ) Tj ET Q q 0 0 0 rg BT 446.35 97.36 Td (from ) Tj ET Q q 0 0 0 rg BT 465.52 97.36 Td (the ) Tj ET Q q 0 0 0 rg BT 478.19 97.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 500.86 97.36 Td (I/II ) Tj ET Q q 0 0 0 rg BT 514.02 97.36 Td (CheckMate-032 ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 88.36 Td (study) Tj ET Q q 0 0 0 rg BT 262.92 88.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 125.25 60.86 Td (V) Tj ET Q q 0 0 0 rg BT 131.25 60.86 Td (arious) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 184.10 60.86 Td (February 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 74.36 Td (BMS ) Tj ET Q q 0 0 0 rg BT 265.12 74.36 Td (and ) Tj ET Q q 0 0 0 rg BT 280.23 74.36 Td (Exelixis ) Tj ET Q q 0 0 0 rg BT 311.83 74.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 352.93 74.36 Td (a ) Tj ET Q q 0 0 0 rg BT 359.03 74.36 Td (clinical ) Tj ET Q q 0 0 0 rg BT 387.63 74.36 Td (development ) Tj ET Q q 0 0 0 rg BT 436.22 74.36 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 485.82 74.36 Td (to ) Tj ET Q q 0 0 0 rg BT 494.93 74.36 Td (evaluate ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 527.02 74.36 Td (Cabometyx) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 567.50 74.36 Td (* ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 65.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 261.32 65.36 Td (Opdivo) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 287.82 65.36 Td (, ) Tj ET Q q 0 0 0 rg BT 291.39 65.36 Td (either ) Tj ET Q q 0 0 0 rg BT 313.20 65.36 Td (alone ) Tj ET Q q 0 0 0 rg BT 334.02 65.36 Td (or ) Tj ET Q q 0 0 0 rg BT 342.84 65.36 Td (in ) Tj ET Q q 0 0 0 rg BT 351.16 65.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 397.48 65.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 414.80 65.36 Td (Y) Tj ET Q q 0 0 0 rg BT 418.98 65.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 438.97 65.36 Td (. ) Tj ET Q q 0 0 0 rg BT 442.44 65.36 Td (The ) Tj ET Q q 0 0 0 rg BT 457.76 65.36 Td (agreement ) Tj ET Q q 0 0 0 rg BT 496.56 65.36 Td (is ) Tj ET Q q 0 0 0 rg BT 503.89 65.36 Td (expected ) Tj ET Q q 0 0 0 rg BT 537.19 65.36 Td (to ) Tj ET Q q 0 0 0 rg BT 545.51 65.36 Td (include ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 56.36 Td (a ) Tj ET Q q 0 0 0 rg BT 250.51 56.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 274.02 56.36 Td (III ) Tj ET Q q 0 0 0 rg BT 285.52 56.36 Td (study ) Tj ET Q q 0 0 0 rg BT 307.54 56.36 Td (in ) Tj ET Q q 0 0 0 rg BT 317.05 56.36 Td (first-line ) Tj ET Q q 0 0 0 rg BT 350.55 56.36 Td (RCC ) Tj ET Q q 0 0 0 rg BT 371.07 56.36 Td (with ) Tj ET Q q 0 0 0 rg BT 389.59 56.36 Td (additional ) Tj ET Q q 0 0 0 rg BT 428.09 56.36 Td (studies ) Tj ET Q q 0 0 0 rg BT 455.60 56.36 Td (planned ) Tj ET Q q 0 0 0 rg BT 486.61 56.36 Td (in ) Tj ET Q q 0 0 0 rg BT 496.12 56.36 Td (bladder ) Tj ET Q q 0 0 0 rg BT 525.62 56.36 Td (cancer) Tj ET Q q 0 0 0 rg BT 548.73 56.36 Td (, ) Tj ET Q q 0 0 0 rg BT 553.50 56.36 Td (HCC ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 47.36 Td (and ) Tj ET Q q 0 0 0 rg BT 259.24 47.36 Td (potentially ) Tj ET Q q 0 0 0 rg BT 299.99 47.36 Td (other ) Tj ET Q q 0 0 0 rg BT 320.73 47.36 Td (tumor ) Tj ET Q q 0 0 0 rg BT 344.48 47.36 Td (types.) Tj ET Q endstream endobj 109 0 obj <> endobj 110 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (54) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 755 m 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 750.5 m 35.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 750.5 m 98.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 750.5 m 98.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 750.5 m 180.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 750.5 m 180.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 750.5 m 241.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 750.5 m 241.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 750.5 m 575.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 750.5 m 575.5 750.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 709.5 m 35.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 709.5 m 98.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 709.5 m 180.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 709.5 m 241.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 709.5 m 575.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 709.5 m 575.5 709.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 686.5 m 35.5 645.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 98.5 686.5 m 98.5 645.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 180.5 686.5 m 180.5 645.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 686.5 m 241.5 645.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 575.5 686.5 m 575.5 645.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 241.5 686.5 m 575.5 686.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 645.5 m 35.5 613.5 l s 0 0 0 RG /GS0 gs 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Tj ET Q q 0 0 0 rg BT 380.59 741.36 Td (data ) Tj ET Q q 0 0 0 rg BT 398.11 741.36 Td (analysis ) Tj ET Q q 0 0 0 rg BT 429.63 741.36 Td (of ) Tj ET Q q 0 0 0 rg BT 439.65 741.36 Td (the ) Tj ET Q q 0 0 0 rg BT 453.18 741.36 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 471.71 741.36 Td (Humana ) Tj ET Q q 0 0 0 rg BT 504.72 741.36 Td (database, ) Tj ET Q q 0 0 0 rg BT 540.48 741.36 Td (in ) Tj ET Q q 0 0 0 rg BT 550.01 741.36 Td (which ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 732.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 281.53 732.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 301.09 732.36 Td (Eliquis) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 326.59 732.36 Td ( ) Tj ET Q q 0 0 0 rg BT 330.14 732.36 Td (was ) Tj ET Q q 0 0 0 rg BT 347.69 732.36 Td (associated ) Tj ET Q q 0 0 0 rg BT 388.22 732.36 Td (with ) Tj ET Q q 0 0 0 rg BT 407.78 732.36 Td (a ) Tj ET Q q 0 0 0 rg BT 415.32 732.36 Td (significantly ) Tj ET Q q 0 0 0 rg BT 463.87 732.36 Td (lower ) Tj ET Q q 0 0 0 rg BT 487.91 732.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 504.96 732.36 Td (of ) Tj ET Q q 0 0 0 rg BT 516.01 732.36 Td (stroke/systemic ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 723.36 Td (embolism ) Tj ET Q q 0 0 0 rg BT 281.61 723.36 Td (and ) Tj ET Q q 0 0 0 rg BT 296.72 723.36 Td (lower ) Tj ET Q q 0 0 0 rg BT 319.33 723.36 Td (rates ) Tj ET Q q 0 0 0 rg BT 338.43 723.36 Td (of ) Tj ET Q q 0 0 0 rg BT 348.05 723.36 Td (major ) Tj ET Q q 0 0 0 rg BT 371.15 723.36 Td (bleeding ) Tj ET Q q 0 0 0 rg BT 404.26 723.36 Td (compared ) Tj ET Q q 0 0 0 rg BT 441.85 723.36 Td (to ) Tj ET Q q 0 0 0 rg BT 450.97 723.36 Td (warfarin ) Tj ET Q q 0 0 0 rg BT 483.56 723.36 Td (in ) Tj ET Q q 0 0 0 rg BT 492.68 723.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 522.79 723.36 Td (aged ) Tj ET Q q 0 0 0 rg BT 541.89 723.36 Td (65 ) Tj ET Q q 0 0 0 rg BT 553.01 723.36 Td (years ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 714.36 Td (and ) Tj ET Q q 0 0 0 rg BT 259.24 714.36 Td (older ) Tj ET Q q 0 0 0 rg BT 279.99 714.36 Td (with ) Tj ET Q q 0 0 0 rg BT 298.24 714.36 Td (NV) Tj ET Q q 0 0 0 rg BT 310.08 714.36 Td (AF) Tj ET Q q 0 0 0 rg BT 320.86 714.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 700.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.34 700.36 Td (data ) Tj ET Q q 0 0 0 rg BT 306.17 700.36 Td (from ) Tj ET Q q 0 0 0 rg BT 326.51 700.36 Td (EMANA) Tj ET Q q 0 0 0 rg BT 358.51 700.36 Td (TE, ) Tj ET Q q 0 0 0 rg BT 374.61 700.36 Td (a ) Tj ET Q q 0 0 0 rg BT 381.45 700.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 405.29 700.36 Td (IV) Tj ET Q q 0 0 0 rg BT 414.63 700.36 Td ( ) Tj ET Q q 0 0 0 rg BT 417.47 700.36 Td (study) Tj ET Q q 0 0 0 rg BT 436.39 700.36 Td (, ) Tj ET Q q 0 0 0 rg BT 441.49 700.36 Td (exploring ) Tj ET Q q 0 0 0 rg BT 478.83 700.36 Td (the ) Tj ET Q q 0 0 0 rg BT 492.67 700.36 Td (safety ) Tj ET Q q 0 0 0 rg BT 517.00 700.36 Td (and ) Tj ET Q q 0 0 0 rg BT 532.85 700.36 Td (ef) Tj ET Q q 0 0 0 rg BT 539.67 700.36 Td (ficacy ) Tj ET Q q 0 0 0 rg BT 564.50 700.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 244.00 691.35 Td (Eliquis) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 269.50 691.35 Td ( ) Tj ET Q q 0 0 0 rg BT 271.75 691.35 Td (in ) Tj ET Q q 0 0 0 rg BT 281.00 691.35 Td (patients ) Tj ET Q q 0 0 0 rg BT 311.25 691.35 Td (with ) Tj ET Q q 0 0 0 rg BT 329.50 691.35 Td (NV) Tj ET Q q 0 0 0 rg BT 341.33 691.35 Td (AF ) Tj ET Q q 0 0 0 rg BT 355.09 691.35 Td (under) Tj ET Q q 0 0 0 rg BT 375.42 691.35 Td (going ) Tj ET Q q 0 0 0 rg BT 398.17 691.35 Td (cardioversion.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 677.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.39 677.36 Td (results ) Tj ET Q q 0 0 0 rg BT 314.78 677.36 Td (from ) Tj ET Q q 0 0 0 rg BT 335.17 677.36 Td (a ) Tj ET Q q 0 0 0 rg BT 342.06 677.36 Td (real-world ) Tj ET Q q 0 0 0 rg BT 382.44 677.36 Td (data ) Tj ET Q q 0 0 0 rg BT 400.33 677.36 Td (analysis ) Tj ET Q q 0 0 0 rg BT 432.22 677.36 Td (pooled ) Tj ET Q q 0 0 0 rg BT 459.61 677.36 Td (from ) Tj ET Q q 0 0 0 rg BT 480.00 677.36 Td (four ) Tj ET Q q 0 0 0 rg BT 497.90 677.36 Td (lar) Tj ET Q q 0 0 0 rg BT 507.22 677.36 Td (ge ) Tj ET Q q 0 0 0 rg BT 518.62 677.36 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 537.52 677.36 Td (insurance ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 668.36 Td (claims ) Tj ET Q q 0 0 0 rg BT 269.37 668.36 Td (databases, ) Tj ET Q q 0 0 0 rg BT 307.99 668.36 Td (in ) Tj ET Q q 0 0 0 rg BT 316.87 668.36 Td (which ) Tj ET Q q 0 0 0 rg BT 340.75 668.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 376.61 668.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 394.49 668.36 Td (Eliquis) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 419.99 668.36 Td ( ) Tj ET Q q 0 0 0 rg BT 421.87 668.36 Td (was ) Tj ET Q q 0 0 0 rg BT 437.75 668.36 Td (associated ) Tj ET Q q 0 0 0 rg BT 476.62 668.36 Td (with ) Tj ET Q q 0 0 0 rg BT 494.50 668.36 Td (a ) Tj ET Q q 0 0 0 rg BT 500.37 668.36 Td (lower ) Tj ET Q q 0 0 0 rg BT 522.75 668.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 538.13 668.36 Td (of ) Tj ET Q q 0 0 0 rg BT 547.50 668.36 Td (stroke/) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 659.36 Td (systemic ) Tj ET Q q 0 0 0 rg BT 277.93 659.36 Td (embolism ) Tj ET Q q 0 0 0 rg BT 315.86 659.36 Td (and ) Tj ET Q q 0 0 0 rg BT 331.29 659.36 Td (lower ) Tj ET Q q 0 0 0 rg BT 354.21 659.36 Td (rates ) Tj ET Q q 0 0 0 rg BT 373.63 659.36 Td (of ) Tj ET Q q 0 0 0 rg BT 383.56 659.36 Td (major ) Tj ET Q q 0 0 0 rg BT 406.99 659.36 Td (bleeding ) Tj ET Q q 0 0 0 rg BT 440.41 659.36 Td (compared ) Tj ET Q q 0 0 0 rg BT 478.33 659.36 Td (to ) Tj ET Q q 0 0 0 rg BT 487.76 659.36 Td (warfarin ) Tj ET Q q 0 0 0 rg BT 520.67 659.36 Td (for ) Tj ET Q q 0 0 0 rg BT 533.60 659.36 Td (the ) Tj ET Q q 0 0 0 rg BT 547.03 659.36 Td (overall ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 650.36 Td (population ) Tj ET Q q 0 0 0 rg BT 284.75 650.36 Td (and ) Tj ET Q q 0 0 0 rg BT 299.99 650.36 Td (for ) Tj ET Q q 0 0 0 rg BT 312.73 650.36 Td (each ) Tj ET Q q 0 0 0 rg BT 331.47 650.36 Td (of ) Tj ET Q q 0 0 0 rg BT 341.22 650.36 Td (the ) Tj ET Q q 0 0 0 rg BT 354.46 650.36 Td (selected ) Tj ET Q q 0 0 0 rg BT 385.69 650.36 Td (high-risk ) Tj ET Q q 0 0 0 rg BT 420.44 650.36 Td (patient ) Tj ET Q q 0 0 0 rg BT 447.18 650.36 Td (sub-populations.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 188.60 627.36 Td (March 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 636.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 286.83 636.36 Td (findings ) Tj ET Q q 0 0 0 rg BT 317.67 636.36 Td (from ) Tj ET Q q 0 0 0 rg BT 336.51 636.36 Td (a ) Tj ET Q q 0 0 0 rg BT 341.85 636.36 Td (real-world ) Tj ET Q q 0 0 0 rg BT 380.67 636.36 Td (data ) Tj ET Q q 0 0 0 rg BT 397.01 636.36 Td (analysis ) Tj ET Q q 0 0 0 rg BT 427.34 636.36 Td (of ) Tj ET Q q 0 0 0 rg BT 436.18 636.36 Td (the ) Tj ET Q q 0 0 0 rg BT 448.52 636.36 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 465.87 636.36 Td (Medicare ) Tj ET Q q 0 0 0 rg BT 501.19 636.36 Td (database ) Tj ET Q q 0 0 0 rg BT 533.51 636.36 Td (comparing ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 627.36 Td (the ) Tj ET Q q 0 0 0 rg BT 256.90 627.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 272.31 627.36 Td (of ) Tj ET Q q 0 0 0 rg BT 281.71 627.36 Td (stroke ) Tj ET Q q 0 0 0 rg BT 305.61 627.36 Td (or ) Tj ET Q q 0 0 0 rg BT 315.01 627.36 Td (systemic ) Tj ET Q q 0 0 0 rg BT 348.41 627.36 Td (embolism ) Tj ET Q q 0 0 0 rg BT 385.82 627.36 Td (and ) Tj ET Q q 0 0 0 rg BT 400.72 627.36 Td (rate ) Tj ET Q q 0 0 0 rg BT 416.11 627.36 Td (of ) Tj ET Q q 0 0 0 rg BT 425.51 627.36 Td (major ) Tj ET Q q 0 0 0 rg BT 448.41 627.36 Td (bleeding ) Tj ET Q q 0 0 0 rg BT 481.30 627.36 Td (among ) Tj ET Q q 0 0 0 rg BT 507.70 627.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 537.60 627.36 Td (with ) Tj ET Q q 0 0 0 rg BT 555.51 627.36 Td (non-) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 618.36 Td (valvular ) Tj ET Q q 0 0 0 rg BT 275.74 618.36 Td (atrial ) Tj ET Q q 0 0 0 rg BT 296.48 618.36 Td (fibrillation ) Tj ET Q q 0 0 0 rg BT 337.22 618.36 Td (who ) Tj ET Q q 0 0 0 rg BT 354.97 618.36 Td (were ) Tj ET Q q 0 0 0 rg BT 374.70 618.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 401.43 618.36 Td (with ) Tj ET Q q 0 0 0 rg BT 419.68 618.36 Td (direct ) Tj ET Q q 0 0 0 rg BT 442.42 618.36 Td (oral ) Tj ET Q q 0 0 0 rg BT 458.66 618.36 Td (anticoagulants ) Tj ET Q q 0 0 0 rg BT 512.90 618.36 Td (versus ) Tj ET Q q 0 0 0 rg BT 538.14 618.36 Td (warfarin.) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 51.50 562.45 Td (Orencia) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 131.70 573.86 Td (PsA) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.85 573.86 Td (July 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 594.36 Td (EC ) Tj ET Q q 0 0 0 rg BT 258.44 594.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 292.87 594.36 Td (for ) Tj ET Q q 0 0 0 rg BT 306.30 594.36 Td (the ) Tj ET Q q 0 0 0 rg BT 320.23 594.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 357.15 594.36 Td (of ) Tj ET Q q 0 0 0 rg BT 367.59 594.36 Td (active ) Tj ET Q q 0 0 0 rg BT 392.01 594.36 Td (PsA) Tj ET Q q 0 0 0 rg BT 406.77 594.36 Td ( ) Tj ET Q q 0 0 0 rg BT 409.46 594.36 Td (in ) Tj ET Q q 0 0 0 rg BT 419.40 594.36 Td (adults ) Tj ET Q q 0 0 0 rg BT 443.84 594.36 Td (for ) Tj ET Q q 0 0 0 rg BT 457.27 594.36 Td (whom ) Tj ET Q q 0 0 0 rg BT 482.71 594.36 Td (the ) Tj ET Q q 0 0 0 rg BT 496.65 594.36 Td (response ) Tj ET Q q 0 0 0 rg BT 531.08 594.36 Td (to ) Tj ET Q q 0 0 0 rg BT 541.02 594.36 Td (previous ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 585.36 Td (disease-modifying ) Tj ET Q q 0 0 0 rg BT 312.17 585.36 Td (antirheumatic ) Tj ET Q q 0 0 0 rg BT 363.33 585.36 Td (drug ) Tj ET Q q 0 0 0 rg BT 381.50 585.36 Td (therapy) Tj ET Q q 0 0 0 rg BT 408.20 585.36 Td (, ) Tj ET Q q 0 0 0 rg BT 411.84 585.36 Td (including ) Tj ET Q q 0 0 0 rg BT 447.51 585.36 Td (methotrexate, ) Tj ET Q q 0 0 0 rg BT 498.42 585.36 Td (has ) Tj ET Q q 0 0 0 rg BT 512.10 585.36 Td (been ) Tj ET Q q 0 0 0 rg BT 530.77 585.36 Td (inadequate, ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 576.36 Td (and ) Tj ET Q q 0 0 0 rg BT 259.24 576.36 Td (additional ) Tj ET Q q 0 0 0 rg BT 297.49 576.36 Td (systemic ) Tj ET Q q 0 0 0 rg BT 331.23 576.36 Td (therapy ) Tj ET Q q 0 0 0 rg BT 360.47 576.36 Td (for ) Tj ET Q q 0 0 0 rg BT 373.21 576.36 Td (psoriatic ) Tj ET Q q 0 0 0 rg BT 406.45 576.36 Td (skin ) Tj ET Q q 0 0 0 rg BT 423.71 576.36 Td (lesions ) Tj ET Q q 0 0 0 rg BT 450.96 576.36 Td (is ) Tj ET Q q 0 0 0 rg BT 459.21 576.36 Td (not ) Tj ET Q q 0 0 0 rg BT 472.96 576.36 Td (required.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 562.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.76 562.36 Td ( ) Tj ET Q q 0 0 0 rg BT 263.74 562.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 297.46 562.36 Td (for ) Tj ET Q q 0 0 0 rg BT 310.19 562.36 Td (active ) Tj ET Q q 0 0 0 rg BT 333.91 562.36 Td (PsA) Tj ET Q q 0 0 0 rg BT 348.67 562.36 Td ( ) Tj ET Q q 0 0 0 rg BT 350.65 562.36 Td (in ) Tj ET Q q 0 0 0 rg BT 359.89 562.36 Td (adults, ) Tj ET Q q 0 0 0 rg BT 385.87 562.36 Td (a ) Tj ET Q q 0 0 0 rg BT 392.09 562.36 Td (chronic, ) Tj ET Q q 0 0 0 rg BT 423.56 562.36 Td (inflammatory ) Tj ET Q q 0 0 0 rg BT 474.78 562.36 Td (disease ) Tj ET Q q 0 0 0 rg BT 503.01 562.36 Td (that ) Tj ET Q q 0 0 0 rg BT 518.74 562.36 Td (can ) Tj ET Q q 0 0 0 rg BT 533.46 562.36 Td (af) Tj ET Q q 0 0 0 rg BT 540.37 562.36 Td (fect ) Tj ET Q q 0 0 0 rg BT 556.01 562.36 Td (both ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 553.36 Td (the ) Tj ET Q q 0 0 0 rg BT 257.25 553.36 Td (skin ) Tj ET Q q 0 0 0 rg BT 274.50 553.36 Td (and ) Tj ET Q q 0 0 0 rg BT 289.74 553.36 Td (musculoskeletal ) Tj ET Q q 0 0 0 rg BT 349.98 553.36 Td (system.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 132.70 534.86 Td (JIA) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 188.60 534.86 Td (March 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 539.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.76 539.36 Td ( ) Tj ET Q q 0 0 0 rg BT 263.76 539.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 297.51 539.36 Td (of ) Tj ET Q q 0 0 0 rg BT 307.26 539.36 Td (a ) Tj ET Q q 0 0 0 rg BT 313.51 539.36 Td (new ) Tj ET Q q 0 0 0 rg BT 330.76 539.36 Td (subcutaneous ) Tj ET Q q 0 0 0 rg BT 381.50 539.36 Td (administration ) Tj ET Q q 0 0 0 rg BT 435.75 539.36 Td (option ) Tj ET Q q 0 0 0 rg BT 461.01 539.36 Td (for ) Tj ET Q q 0 0 0 rg BT 473.75 539.36 Td (use ) Tj ET Q q 0 0 0 rg BT 488.01 539.36 Td (in ) Tj ET Q q 0 0 0 rg BT 497.26 539.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 527.51 539.36 Td (two ) Tj ET Q q 0 0 0 rg BT 543.27 539.36 Td (years ) Tj ET Q q 0 0 0 rg BT 564.51 539.36 Td (of ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 530.36 Td (age ) Tj ET Q q 0 0 0 rg BT 258.74 530.36 Td (and ) Tj ET Q q 0 0 0 rg BT 273.98 530.36 Td (older ) Tj ET Q q 0 0 0 rg BT 294.73 530.36 Td (with ) Tj ET Q q 0 0 0 rg BT 312.98 530.36 Td (moderately ) Tj ET Q q 0 0 0 rg BT 355.71 530.36 Td (to ) Tj ET Q q 0 0 0 rg BT 364.96 530.36 Td (severely ) Tj ET Q q 0 0 0 rg BT 397.19 530.36 Td (active ) Tj ET Q q 0 0 0 rg BT 420.93 530.36 Td (polyarticular ) Tj ET Q q 0 0 0 rg BT 469.16 530.36 Td (JIA.) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 52.75 458.45 Td (Sprycel) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 130.40 497.36 Td (ALL) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.00 501.86 Td (December) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 492.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 506.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 289.62 506.36 Td (data ) Tj ET Q q 0 0 0 rg BT 308.74 506.36 Td (from ) Tj ET Q q 0 0 0 rg BT 330.36 506.36 Td (the ) Tj ET Q q 0 0 0 rg BT 345.49 506.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 370.62 506.36 Td (II ) Tj ET Q q 0 0 0 rg BT 380.74 506.36 Td (CA180-372 ) Tj ET Q q 0 0 0 rg BT 427.37 506.36 Td (study ) Tj ET Q q 0 0 0 rg BT 451.00 506.36 Td (in ) Tj ET Q q 0 0 0 rg BT 462.14 506.36 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 497.75 506.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 529.87 506.36 Td (with ) Tj ET Q q 0 0 0 rg BT 550.00 506.36 Td (newly ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 497.36 Td (diagnosed ) Tj ET Q q 0 0 0 rg BT 286.35 497.36 Td (Philadelphia ) Tj ET Q q 0 0 0 rg BT 337.20 497.36 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 419.75 497.36 Td (ALL) Tj ET Q q 0 0 0 rg BT 436.91 497.36 Td ( ) Tj ET Q q 0 0 0 rg BT 442.76 497.36 Td (treated ) Tj ET Q q 0 0 0 rg BT 473.10 497.36 Td (with ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 494.96 497.36 Td (Sprycel) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 521.95 497.36 Td ( ) Tj ET Q q 0 0 0 rg BT 527.80 497.36 Td (added ) Tj ET Q q 0 0 0 rg BT 555.15 497.36 Td (to ) Tj ET Q q 0 0 0 rg BT 568.00 497.36 Td (a ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 488.36 Td (chemotherapy ) Tj ET Q q 0 0 0 rg BT 297.23 488.36 Td (regimen.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.40 442.36 Td (CML) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.50 474.36 Td (November) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 465.36 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 474.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.51 474.36 Td ( ) Tj ET Q q 0 0 0 rg BT 264.32 474.36 Td (expanded ) Tj ET Q q 0 0 0 rg BT 301.62 474.36 Td (the ) Tj ET Q q 0 0 0 rg BT 315.43 474.36 Td (indication ) Tj ET Q q 0 0 0 rg BT 354.24 474.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 367.55 474.36 Td (Sprycel) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 394.53 474.36 Td ( ) Tj ET Q q 0 0 0 rg BT 397.35 474.36 Td (tablets ) Tj ET Q q 0 0 0 rg BT 423.66 474.36 Td (to ) Tj ET Q q 0 0 0 rg BT 433.47 474.36 Td (include ) Tj ET Q q 0 0 0 rg BT 462.78 474.36 Td (the ) Tj ET Q q 0 0 0 rg BT 476.59 474.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 513.39 474.36 Td (of ) Tj ET Q q 0 0 0 rg BT 523.70 474.36 Td (children ) Tj ET Q q 0 0 0 rg BT 556.00 474.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 465.36 Td (Philadelphia ) Tj ET Q q 0 0 0 rg BT 291.24 465.36 Td (chromosome-positive ) Tj ET Q q 0 0 0 rg BT 371.48 465.36 Td (CML) Tj ET Q q 0 0 0 rg BT 390.65 465.36 Td ( ) Tj ET Q q 0 0 0 rg BT 392.90 465.36 Td (in ) Tj ET Q q 0 0 0 rg BT 402.15 465.36 Td (chronic ) Tj ET Q q 0 0 0 rg BT 431.38 465.36 Td (phase.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 446.86 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 451.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.27 451.36 Td (data ) Tj ET Q q 0 0 0 rg BT 304.04 451.36 Td (from ) Tj ET Q q 0 0 0 rg BT 323.31 451.36 Td (the ) Tj ET Q q 0 0 0 rg BT 336.09 451.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 358.86 451.36 Td (II ) Tj ET Q q 0 0 0 rg BT 366.64 451.36 Td (CA180-226 ) Tj ET Q q 0 0 0 rg BT 410.92 451.36 Td (study ) Tj ET Q q 0 0 0 rg BT 432.20 451.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 471.47 451.36 Td (Sprycel) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 498.45 451.36 Td ( ) Tj ET Q q 0 0 0 rg BT 500.23 451.36 Td (in ) Tj ET Q q 0 0 0 rg BT 509.01 451.36 Td (imatinib-resistant ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 442.36 Td (or ) Tj ET Q q 0 0 0 rg BT 253.75 442.36 Td (-intolerant ) Tj ET Q q 0 0 0 rg BT 293.48 442.36 Td (and ) Tj ET Q q 0 0 0 rg BT 308.73 442.36 Td (newly ) Tj ET Q q 0 0 0 rg BT 332.97 442.36 Td (diagnosed ) Tj ET Q q 0 0 0 rg BT 371.71 442.36 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 405.45 442.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 435.69 442.36 Td (with ) Tj ET Q q 0 0 0 rg BT 453.94 442.36 Td (chronic ) Tj ET Q q 0 0 0 rg BT 483.18 442.36 Td (phase ) Tj ET Q q 0 0 0 rg BT 505.92 442.36 Td (CML.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 419.36 Td (May 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 428.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 287.31 428.36 Td (the ) Tj ET Q q 0 0 0 rg BT 300.13 428.36 Td (EMA) Tj ET Q q 0 0 0 rg BT 319.88 428.36 Td ( ) Tj ET Q q 0 0 0 rg BT 321.45 428.36 Td (validated ) Tj ET Q q 0 0 0 rg BT 356.26 428.36 Td (its ) Tj ET Q q 0 0 0 rg BT 366.58 428.36 Td (grouped ) Tj ET Q q 0 0 0 rg BT 397.85 428.36 Td (T) Tj ET Q q 0 0 0 rg BT 402.95 428.36 Td (ype ) Tj ET Q q 0 0 0 rg BT 417.45 428.36 Td (II ) Tj ET Q q 0 0 0 rg BT 425.27 428.36 Td (variation/extension ) Tj ET Q q 0 0 0 rg BT 496.07 428.36 Td (of ) Tj ET Q q 0 0 0 rg BT 505.39 428.36 Td (application ) Tj ET Q q 0 0 0 rg BT 547.20 428.36 Td (to ) Tj ET Q q 0 0 0 rg BT 556.02 428.36 Td (treat ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 419.36 Td (children ) Tj ET Q q 0 0 0 rg BT 274.80 419.36 Td (and ) Tj ET Q q 0 0 0 rg BT 289.11 419.36 Td (adolescents ) Tj ET Q q 0 0 0 rg BT 331.92 419.36 Td (aged ) Tj ET Q q 0 0 0 rg BT 350.22 419.36 Td (1 ) Tj ET Q q 0 0 0 rg BT 356.04 419.36 Td (year ) Tj ET Q q 0 0 0 rg BT 372.84 419.36 Td (to ) Tj ET Q q 0 0 0 rg BT 381.16 419.36 Td (18 ) Tj ET Q q 0 0 0 rg BT 391.47 419.36 Td (years ) Tj ET Q q 0 0 0 rg BT 411.78 419.36 Td (with ) Tj ET Q q 0 0 0 rg BT 429.10 419.36 Td (chronic ) Tj ET Q q 0 0 0 rg BT 457.40 419.36 Td (phase ) Tj ET Q q 0 0 0 rg BT 479.21 419.36 Td (Philadelphia ) Tj ET Q q 0 0 0 rg BT 525.51 419.36 Td (chromosome ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 410.36 Td (positive ) Tj ET Q q 0 0 0 rg BT 274.75 410.36 Td (CML) Tj ET Q q 0 0 0 rg BT 294.08 410.36 Td ( ) Tj ET Q q 0 0 0 rg BT 296.17 410.36 Td (and ) Tj ET Q q 0 0 0 rg BT 311.41 410.36 Td (to ) Tj ET Q q 0 0 0 rg BT 320.66 410.36 Td (include ) Tj ET Q q 0 0 0 rg BT 349.40 410.36 Td (the ) Tj ET Q q 0 0 0 rg BT 362.65 410.36 Td (powder ) Tj ET Q q 0 0 0 rg BT 391.89 410.36 Td (for ) Tj ET Q q 0 0 0 rg BT 404.63 410.36 Td (oral ) Tj ET Q q 0 0 0 rg BT 420.88 410.36 Td (suspension.) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 54.25 333.95 Td (Y) Tj ET Q q 0 0 0 rg BT 59.25 333.95 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 119.75 333.86 Td (Melanoma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 186.35 381.86 Td (January 2018) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 386.36 Td (EC ) Tj ET Q q 0 0 0 rg BT 259.39 386.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 294.76 386.36 Td (of ) Tj ET Q q 0 0 0 rg BT 306.14 386.36 Td (an ) Tj ET Q q 0 0 0 rg BT 318.52 386.36 Td (expanded ) Tj ET Q q 0 0 0 rg BT 356.89 386.36 Td (indication ) Tj ET Q q 0 0 0 rg BT 396.77 386.36 Td (for ) Tj ET Q q 0 0 0 rg BT 411.15 386.36 Td (the ) Tj ET Q q 0 0 0 rg BT 426.03 386.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 463.89 386.36 Td (of ) Tj ET Q q 0 0 0 rg BT 475.28 386.36 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 524.13 386.36 Td (or ) Tj ET Q q 0 0 0 rg BT 535.52 386.36 Td (metastatic ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 377.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 283.74 377.36 Td (in ) Tj ET Q q 0 0 0 rg BT 292.99 377.36 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 326.72 377.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 356.96 377.36 Td (12 ) Tj ET Q q 0 0 0 rg BT 368.21 377.36 Td (years ) Tj ET Q q 0 0 0 rg BT 389.45 377.36 Td (of ) Tj ET Q q 0 0 0 rg BT 399.20 377.36 Td (age ) Tj ET Q q 0 0 0 rg BT 413.94 377.36 Td (and ) Tj ET Q q 0 0 0 rg BT 429.18 377.36 Td (older) Tj ET Q q 0 0 0 rg BT 447.42 377.36 Td (.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 185.85 349.86 Td (October 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 363.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.33 363.36 Td (the ) Tj ET Q q 0 0 0 rg BT 302.17 363.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 319.67 363.36 Td ( ) Tj ET Q q 0 0 0 rg BT 322.52 363.36 Td (added ) Tj ET Q q 0 0 0 rg BT 346.85 363.36 Td (five-year ) Tj ET Q q 0 0 0 rg BT 382.16 363.36 Td (overall ) Tj ET Q q 0 0 0 rg BT 409.99 363.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 441.83 363.36 Td (data ) Tj ET Q q 0 0 0 rg BT 459.66 363.36 Td (from ) Tj ET Q q 0 0 0 rg BT 480.00 363.36 Td (the ) Tj ET Q q 0 0 0 rg BT 493.83 363.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 517.67 363.36 Td (III ) Tj ET Q q 0 0 0 rg BT 529.50 363.36 Td (CA184-029 ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 354.36 Td (study ) Tj ET Q q 0 0 0 rg BT 266.04 354.36 Td (to ) Tj ET Q q 0 0 0 rg BT 275.58 354.36 Td (the ) Tj ET Q q 0 0 0 rg BT 289.12 354.36 Td (prescribing ) Tj ET Q q 0 0 0 rg BT 332.14 354.36 Td (information ) Tj ET Q q 0 0 0 rg BT 377.17 354.36 Td (for ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 389.92 354.36 Td (Y) Tj ET Q q 0 0 0 rg BT 394.09 354.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 414.08 354.36 Td ( for ) Tj ET Q q 0 0 0 rg BT 429.36 354.36 Td (the ) Tj ET Q q 0 0 0 rg BT 442.90 354.36 Td (adjuvant ) Tj ET Q q 0 0 0 rg BT 476.43 354.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 512.95 354.36 Td (of ) Tj ET Q q 0 0 0 rg BT 522.99 354.36 Td (fully ) Tj ET Q q 0 0 0 rg BT 542.52 354.36 Td (resected ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 345.36 Td (cutaneous ) Tj ET Q q 0 0 0 rg BT 282.37 345.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 322.24 345.36 Td (with ) Tj ET Q q 0 0 0 rg BT 340.62 345.36 Td (pathologic ) Tj ET Q q 0 0 0 rg BT 380.99 345.36 Td (involvement ) Tj ET Q q 0 0 0 rg BT 428.36 345.36 Td (of ) Tj ET Q q 0 0 0 rg BT 438.24 345.36 Td (regional ) Tj ET Q q 0 0 0 rg BT 470.11 345.36 Td (lymph ) Tj ET Q q 0 0 0 rg BT 495.49 345.36 Td (nodes ) Tj ET Q q 0 0 0 rg BT 518.87 345.36 Td (of ) Tj ET Q q 0 0 0 rg BT 528.75 345.36 Td (more ) Tj ET Q q 0 0 0 rg BT 549.63 345.36 Td (than ) Tj ET Q q 0 0 0 rg BT 567.50 345.36 Td (1 ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 336.36 Td (mm.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.85 317.86 Td (July 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 322.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 261.51 322.36 Td ( ) Tj ET Q q 0 0 0 rg BT 264.89 322.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 299.76 322.36 Td (of ) Tj ET Q q 0 0 0 rg BT 310.65 322.36 Td (an ) Tj ET Q q 0 0 0 rg BT 322.53 322.36 Td (expanded ) Tj ET Q q 0 0 0 rg BT 360.39 322.36 Td (indication ) Tj ET Q q 0 0 0 rg BT 399.77 322.36 Td (for ) Tj ET Q q 0 0 0 rg BT 413.65 322.36 Td (the ) Tj ET Q q 0 0 0 rg BT 428.03 322.36 Td (treatment ) Tj ET Q q 0 0 0 rg BT 465.40 322.36 Td (of ) Tj ET Q q 0 0 0 rg BT 476.28 322.36 Td (unresectable ) Tj ET Q q 0 0 0 rg BT 524.64 322.36 Td (or ) Tj ET Q q 0 0 0 rg BT 535.52 322.36 Td (metastatic ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 313.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 283.74 313.36 Td (in ) Tj ET Q q 0 0 0 rg BT 292.99 313.36 Td (pediatric ) Tj ET Q q 0 0 0 rg BT 326.72 313.36 Td (patients.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 290.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 299.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 288.11 299.36 Td (relapse-free ) Tj ET Q q 0 0 0 rg BT 333.19 299.36 Td (survival ) Tj ET Q q 0 0 0 rg BT 364.81 299.36 Td (results ) Tj ET Q q 0 0 0 rg BT 390.92 299.36 Td (from ) Tj ET Q q 0 0 0 rg BT 411.04 299.36 Td (a ) Tj ET Q q 0 0 0 rg BT 417.65 299.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 441.27 299.36 Td (III ) Tj ET Q q 0 0 0 rg BT 452.88 299.36 Td (study ) Tj ET Q q 0 0 0 rg BT 475.00 299.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 515.10 299.36 Td (Y) Tj ET Q q 0 0 0 rg BT 519.28 299.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 539.27 299.36 Td ( ) Tj ET Q q 0 0 0 rg BT 541.89 299.36 Td (3 ) Tj ET Q q 0 0 0 rg BT 549.01 299.36 Td (mg/kg ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 290.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 259.57 290.36 Td (Y) Tj ET Q q 0 0 0 rg BT 263.75 290.36 Td (ervoy) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 283.73 290.36 Td ( ) Tj ET Q q 0 0 0 rg BT 286.31 290.36 Td (10mg/kg ) Tj ET Q q 0 0 0 rg BT 320.88 290.36 Td (in ) Tj ET Q q 0 0 0 rg BT 330.45 290.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 361.02 290.36 Td (with ) Tj ET Q q 0 0 0 rg BT 379.59 290.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 400.66 290.36 Td (III ) Tj ET Q q 0 0 0 rg BT 412.22 290.36 Td (or ) Tj ET Q q 0 0 0 rg BT 422.29 290.36 Td (resectable ) Tj ET Q q 0 0 0 rg BT 460.84 290.36 Td (stage ) Tj ET Q q 0 0 0 rg BT 481.91 290.36 Td (IV) Tj ET Q q 0 0 0 rg BT 491.24 290.36 Td ( ) Tj ET Q q 0 0 0 rg BT 493.81 290.36 Td (melanoma ) Tj ET Q q 0 0 0 rg BT 533.87 290.36 Td (who ) Tj ET Q q 0 0 0 rg BT 551.95 290.36 Td (are ) Tj ET Q q 0 0 0 rg BT 565.51 290.36 Td (at ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 281.36 Td (high ) Tj ET Q q 0 0 0 rg BT 262.25 281.36 Td (risk ) Tj ET Q q 0 0 0 rg BT 278.00 281.36 Td (of ) Tj ET Q q 0 0 0 rg BT 287.75 281.36 Td (recurrence ) Tj ET Q q 0 0 0 rg BT 327.96 281.36 Td (following ) Tj ET Q q 0 0 0 rg BT 365.21 281.36 Td (complete ) Tj ET Q q 0 0 0 rg BT 400.45 281.36 Td (sur) Tj ET Q q 0 0 0 rg BT 411.28 281.36 Td (gical ) Tj ET Q q 0 0 0 rg BT 431.02 281.36 Td (resection.) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 49.45 248.45 Td (Empliciti) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 105.10 248.36 Td (Multiple Myeloma) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 192.10 248.36 Td (June 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 257.36 Td (Announced ) Tj ET Q q 0 0 0 rg BT 289.69 257.36 Td (four) Tj ET Q q 0 0 0 rg BT 304.51 257.36 Td (-year ) Tj ET Q q 0 0 0 rg BT 327.20 257.36 Td (follow-up ) Tj ET Q q 0 0 0 rg BT 366.90 257.36 Td (data ) Tj ET Q q 0 0 0 rg BT 386.09 257.36 Td (from ) Tj ET Q q 0 0 0 rg BT 407.80 257.36 Td (a ) Tj ET Q q 0 0 0 rg BT 416.00 257.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 441.20 257.36 Td (III ) Tj ET Q q 0 0 0 rg BT 454.40 257.36 Td (study ) Tj ET Q q 0 0 0 rg BT 478.11 257.36 Td (evaluating ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 519.80 257.36 Td (Empliciti) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 552.79 257.36 Td ( ) Tj ET Q q 0 0 0 rg BT 557.00 257.36 Td (plus ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 248.36 Td (lenalidomide/dexamethasone ) Tj ET Q q 0 0 0 rg BT 355.19 248.36 Td (vs. ) Tj ET Q q 0 0 0 rg BT 371.66 248.36 Td (lenalidomide/dexamethasone ) Tj ET Q q 0 0 0 rg BT 482.85 248.36 Td (alone ) Tj ET Q q 0 0 0 rg BT 508.56 248.36 Td (in ) Tj ET Q q 0 0 0 rg BT 521.78 248.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 248.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 239.36 Td (relapsed/refractory ) Tj ET Q q 0 0 0 rg BT 314.21 239.36 Td (multiple ) Tj ET Q q 0 0 0 rg BT 346.45 239.36 Td (myeloma.) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 44.60 206.45 Td (Hepatitis C) Tj ET Q BT /F2 9.00 Tf ET q 0 0 0 rg BT 47.50 197.45 Td (Franchise) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 129.55 201.86 Td (HCV) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 190.85 201.86 Td (April 2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 215.36 Td (China ) Tj ET Q q 0 0 0 rg BT 270.55 215.36 Td (FDA) Tj ET Q q 0 0 0 rg BT 288.06 215.36 Td ( ) Tj ET Q q 0 0 0 rg BT 293.11 215.36 Td (approval ) Tj ET Q q 0 0 0 rg BT 329.65 215.36 Td (of ) Tj ET Q q 0 0 0 rg BT 342.20 215.36 Td (the ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 358.25 215.36 Td (Daklinza) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 390.75 215.36 Td ( ) Tj ET Q q 0 0 0 rg BT 395.80 215.36 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 413.85 215.36 Td (Sunvepra) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 447.84 215.36 Td ( ) Tj ET Q q 0 0 0 rg BT 452.89 215.36 Td (regimen ) Tj ET Q q 0 0 0 rg BT 487.44 215.36 Td (for ) Tj ET Q q 0 0 0 rg BT 502.98 215.36 Td (treatment-naive ) Tj ET Q q 0 0 0 rg BT 564.51 215.36 Td (or ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 206.36 Td (experienced ) Tj ET Q q 0 0 0 rg BT 290.81 206.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 322.15 206.36 Td (infected ) Tj ET Q q 0 0 0 rg BT 354.47 206.36 Td (with ) Tj ET Q q 0 0 0 rg BT 373.81 206.36 Td (genotype ) Tj ET Q q 0 0 0 rg BT 410.14 206.36 Td (1b ) Tj ET Q q 0 0 0 rg BT 422.48 206.36 Td (chronic ) Tj ET Q q 0 0 0 rg BT 452.81 206.36 Td (HCV) Tj ET Q q 0 0 0 rg BT 470.65 206.36 Td (. ) Tj ET Q q 0 0 0 rg BT 476.24 206.36 Td (In ) Tj ET Q q 0 0 0 rg BT 487.08 206.36 Td (addition, ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 522.17 206.36 Td (Daklinza) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 554.66 206.36 Td ( ) Tj ET Q q 0 0 0 rg BT 558.00 206.36 Td (was ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 197.36 Td (approved ) Tj ET Q q 0 0 0 rg BT 280.52 197.36 Td (in ) Tj ET Q q 0 0 0 rg BT 290.56 197.36 Td (China ) Tj ET Q q 0 0 0 rg BT 315.09 197.36 Td (for ) Tj ET Q q 0 0 0 rg BT 328.62 197.36 Td (combination ) Tj ET Q q 0 0 0 rg BT 376.65 197.36 Td (use ) Tj ET Q q 0 0 0 rg BT 391.68 197.36 Td (with ) Tj ET Q q 0 0 0 rg BT 410.72 197.36 Td (other ) Tj ET Q q 0 0 0 rg BT 432.25 197.36 Td (agents, ) Tj ET Q q 0 0 0 rg BT 460.52 197.36 Td (including ) Tj ET Q q 0 0 0 rg BT 497.55 197.36 Td (sofosbuvir) Tj ET Q q 0 0 0 rg BT 535.19 197.36 Td (, ) Tj ET Q q 0 0 0 rg BT 540.48 197.36 Td (for ) Tj ET Q q 0 0 0 rg BT 554.01 197.36 Td (adult ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 188.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 274.24 188.36 Td (with ) Tj ET Q q 0 0 0 rg BT 292.49 188.36 Td (HCV) Tj ET Q q 0 0 0 rg BT 311.33 188.36 Td ( ) Tj ET Q q 0 0 0 rg BT 313.58 188.36 Td (genotypes ) Tj ET Q q 0 0 0 rg BT 352.33 188.36 Td (1-6 ) Tj ET Q q 0 0 0 rg BT 366.57 188.36 Td (infection.) Tj ET Q BT /F4 9.00 Tf ET q 0 0 0 rg BT 48.25 155.45 Td (Prostvac*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 110.60 155.36 Td (Prostate Cancer) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 191.25 159.86 Td (September) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 201.50 150.86 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 164.36 Td (Bavarian ) Tj ET Q q 0 0 0 rg BT 279.51 164.36 Td (Nordic ) Tj ET Q q 0 0 0 rg BT 306.87 164.36 Td (A/S ) Tj ET Q q 0 0 0 rg BT 323.90 164.36 Td (announced ) Tj ET Q q 0 0 0 rg BT 365.91 164.36 Td (an ) Tj ET Q q 0 0 0 rg BT 377.44 164.36 Td (independent ) Tj ET Q q 0 0 0 rg BT 424.45 164.36 Td (Data ) Tj ET Q q 0 0 0 rg BT 444.47 164.36 Td (Monitoring ) Tj ET Q q 0 0 0 rg BT 488.50 164.36 Td (Committee ) Tj ET Q q 0 0 0 rg BT 531.52 164.36 Td (determined ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 155.36 Td (that ) Tj ET Q q 0 0 0 rg BT 261.46 155.36 Td (the ) Tj ET Q q 0 0 0 rg BT 276.42 155.36 Td (continuation ) Tj ET Q q 0 0 0 rg BT 325.37 155.36 Td (of ) Tj ET Q q 0 0 0 rg BT 336.83 155.36 Td (the ) Tj ET Q q 0 0 0 rg BT 351.79 155.36 Td (Phase ) Tj ET Q q 0 0 0 rg BT 376.75 155.36 Td (III ) Tj ET Q q 0 0 0 rg BT 389.71 155.36 Td (PROSPECT) Tj ET Q q 0 0 0 rg BT 434.06 155.36 Td ( ) Tj ET Q q 0 0 0 rg BT 438.03 155.36 Td (study ) Tj ET Q q 0 0 0 rg BT 461.49 155.36 Td (of ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 472.96 155.36 Td (Pr) Tj ET Q q 0 0 0 rg BT 481.62 155.36 Td (ostvac*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 509.11 155.36 Td ( ) Tj ET Q q 0 0 0 rg BT 513.08 155.36 Td (in ) Tj ET Q q 0 0 0 rg BT 524.04 155.36 Td (patients ) Tj ET Q q 0 0 0 rg BT 556.00 155.36 Td (with ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 244.00 146.36 Td (metastatic ) Tj ET Q q 0 0 0 rg BT 282.73 146.36 Td (castration-resistant ) Tj ET Q q 0 0 0 rg BT 352.96 146.36 Td (prostate ) Tj ET Q q 0 0 0 rg BT 383.70 146.36 Td (cancer ) Tj ET Q q 0 0 0 rg BT 409.42 146.36 Td (is ) Tj ET Q q 0 0 0 rg BT 417.68 146.36 Td (futile.) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 111 0 obj <> endobj 112 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (55) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Special Note Regarding Forward-Looking Statements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 730.05 Td (This ) Tj ET Q q 0 0 0 rg BT 56.19 730.05 Td (annual ) Tj ET Q q 0 0 0 rg BT 85.25 730.05 Td (report ) Tj ET Q q 0 0 0 rg BT 111.53 730.05 Td (on ) Tj ET Q q 0 0 0 rg BT 123.94 730.05 Td (Form ) Tj ET Q q 0 0 0 rg BT 148.02 730.05 Td (10-K ) Tj ET Q q 0 0 0 rg BT 170.98 730.05 Td (\(including ) Tj ET Q q 0 0 0 rg BT 214.49 730.05 Td (documents ) Tj ET Q q 0 0 0 rg BT 260.22 730.05 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 313.16 730.05 Td (by ) Tj ET Q q 0 0 0 rg BT 325.57 730.05 Td (reference\) ) Tj ET Q q 0 0 0 rg BT 368.49 730.05 Td (and ) Tj ET Q q 0 0 0 rg BT 385.33 730.05 Td (other ) Tj ET Q q 0 0 0 rg BT 408.29 730.05 Td (written ) Tj ET Q q 0 0 0 rg BT 439.02 730.05 Td (and ) Tj ET Q q 0 0 0 rg BT 455.86 730.05 Td (oral ) Tj ET Q q 0 0 0 rg BT 473.82 730.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 518.44 730.05 Td (we ) Tj ET Q q 0 0 0 rg BT 532.50 730.05 Td (make ) Tj ET Q q 0 0 0 rg BT 556.57 730.05 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 718.05 Td (time ) Tj ET Q q 0 0 0 rg BT 55.26 718.05 Td (to ) Tj ET Q q 0 0 0 rg BT 64.53 718.05 Td (time ) Tj ET Q q 0 0 0 rg BT 83.79 718.05 Td (contain ) Tj ET Q q 0 0 0 rg BT 114.71 718.05 Td (certain ) Tj ET Q q 0 0 0 rg BT 143.40 718.05 Td (“forward-looking” ) Tj ET Q q 0 0 0 rg BT 219.30 718.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 262.99 718.05 Td (within ) Tj ET Q q 0 0 0 rg BT 290.04 718.05 Td (the ) Tj ET Q q 0 0 0 rg BT 303.74 718.05 Td (meaning ) Tj ET Q q 0 0 0 rg BT 339.66 718.05 Td (of ) Tj ET Q q 0 0 0 rg BT 349.48 718.05 Td (Section 27A) Tj ET Q q 0 0 0 rg BT 398.64 718.05 Td ( ) Tj ET Q q 0 0 0 rg BT 400.13 718.05 Td (of ) Tj ET Q q 0 0 0 rg BT 409.95 718.05 Td (the ) Tj ET Q q 0 0 0 rg BT 423.65 718.05 Td (Securities ) Tj ET Q q 0 0 0 rg BT 464.24 718.05 Td (Act ) Tj ET Q q 0 0 0 rg BT 480.17 718.05 Td (of ) Tj ET Q q 0 0 0 rg BT 489.99 718.05 Td (1933 ) Tj ET Q q 0 0 0 rg BT 511.47 718.05 Td (and ) Tj ET Q q 0 0 0 rg BT 527.40 718.05 Td (Section 21E ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 706.05 Td (of ) Tj ET Q q 0 0 0 rg BT 46.70 706.05 Td (the ) Tj ET Q q 0 0 0 rg BT 61.29 706.05 Td (Securities ) Tj ET Q q 0 0 0 rg BT 103.10 706.05 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 144.37 706.05 Td (Act ) Tj ET Q q 0 0 0 rg BT 161.18 706.05 Td (of ) Tj ET Q q 0 0 0 rg BT 171.88 706.05 Td (1934. ) Tj ET Q q 0 0 0 rg BT 196.40 706.05 Td (Y) Tj ET Q q 0 0 0 rg BT 202.62 706.05 Td (ou ) Tj ET Q q 0 0 0 rg BT 214.99 706.05 Td (can ) Tj ET Q q 0 0 0 rg BT 231.24 706.05 Td (identify ) Tj ET Q q 0 0 0 rg BT 264.72 706.05 Td (these ) Tj ET Q q 0 0 0 rg BT 287.64 706.05 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 355.55 706.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 400.13 706.05 Td (by ) Tj ET Q q 0 0 0 rg BT 412.50 706.05 Td (the ) Tj ET Q q 0 0 0 rg BT 427.09 706.05 Td (fact ) Tj ET Q q 0 0 0 rg BT 444.45 706.05 Td (they ) Tj ET Q q 0 0 0 rg BT 464.04 706.05 Td (use ) Tj ET Q q 0 0 0 rg BT 479.74 706.05 Td (words ) Tj ET Q q 0 0 0 rg BT 506.56 706.05 Td (such ) Tj ET Q q 0 0 0 rg BT 527.26 706.05 Td (as ) Tj ET Q q 0 0 0 rg BT 537.96 706.05 Td (“should”, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 694.05 Td (“expect”, ) Tj ET Q q 0 0 0 rg BT 76.89 694.05 Td (“anticipate”, ) Tj ET Q q 0 0 0 rg BT 130.56 694.05 Td (“estimate”, ) Tj ET Q q 0 0 0 rg BT 178.67 694.05 Td (“tar) Tj ET Q q 0 0 0 rg BT 193.48 694.05 Td (get”, ) Tj ET Q q 0 0 0 rg BT 216.05 694.05 Td (“may”, ) Tj ET Q q 0 0 0 rg BT 248.07 694.05 Td (“project”, ) Tj ET Q q 0 0 0 rg BT 290.63 694.05 Td (“guidance”, ) Tj ET Q q 0 0 0 rg BT 341.52 694.05 Td (“intend”, ) Tj ET Q q 0 0 0 rg BT 381.31 694.05 Td (“plan”, ) Tj ET Q q 0 0 0 rg BT 413.33 694.05 Td (“believe” ) Tj ET Q q 0 0 0 rg BT 454.50 694.05 Td (and ) Tj ET Q q 0 0 0 rg BT 472.35 694.05 Td (other ) Tj ET Q q 0 0 0 rg BT 496.32 694.05 Td (words ) Tj ET Q q 0 0 0 rg BT 524.19 694.05 Td (and ) Tj ET Q q 0 0 0 rg BT 542.04 694.05 Td (terms ) Tj ET Q q 0 0 0 rg BT 567.68 694.05 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 682.05 Td (similar ) Tj ET Q q 0 0 0 rg BT 66.61 682.05 Td (meaning ) Tj ET Q q 0 0 0 rg BT 103.87 682.05 Td (and ) Tj ET Q q 0 0 0 rg BT 121.15 682.05 Td (expression ) Tj ET Q q 0 0 0 rg BT 166.75 682.05 Td (in ) Tj ET Q q 0 0 0 rg BT 177.36 682.05 Td (connection ) Tj ET Q q 0 0 0 rg BT 224.07 682.05 Td (with ) Tj ET Q q 0 0 0 rg BT 244.68 682.05 Td (any ) Tj ET Q q 0 0 0 rg BT 261.95 682.05 Td (discussion ) Tj ET Q q 0 0 0 rg BT 306.45 682.05 Td (of ) Tj ET Q q 0 0 0 rg BT 317.62 682.05 Td (future ) Tj ET Q q 0 0 0 rg BT 344.33 682.05 Td (operating ) Tj ET Q q 0 0 0 rg BT 384.92 682.05 Td (or ) Tj ET Q q 0 0 0 rg BT 396.09 682.05 Td (financial ) Tj ET Q q 0 0 0 rg BT 433.90 682.05 Td (performance. ) Tj ET Q q 0 0 0 rg BT 489.76 682.05 Td (One ) Tj ET Q q 0 0 0 rg BT 509.25 682.05 Td (can ) Tj ET Q q 0 0 0 rg BT 525.96 682.05 Td (also ) Tj ET Q q 0 0 0 rg BT 544.90 682.05 Td (identify ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 670.05 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 104.02 670.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 148.71 670.05 Td (by ) Tj ET Q q 0 0 0 rg BT 161.19 670.05 Td (the ) Tj ET Q q 0 0 0 rg BT 175.89 670.05 Td (fact ) Tj ET Q q 0 0 0 rg BT 193.35 670.05 Td (that ) Tj ET Q q 0 0 0 rg BT 210.83 670.05 Td (they ) Tj ET Q q 0 0 0 rg BT 230.53 670.05 Td (do ) Tj ET Q q 0 0 0 rg BT 243.01 670.05 Td (not ) Tj ET Q q 0 0 0 rg BT 258.27 670.05 Td (relate ) Tj ET Q q 0 0 0 rg BT 282.95 670.05 Td (strictly ) Tj ET Q q 0 0 0 rg BT 313.20 670.05 Td (to ) Tj ET Q q 0 0 0 rg BT 323.46 670.05 Td (historical ) Tj ET Q q 0 0 0 rg BT 363.15 670.05 Td (or ) Tj ET Q q 0 0 0 rg BT 373.96 670.05 Td (current ) Tj ET Q q 0 0 0 rg BT 404.76 670.05 Td (facts. ) Tj ET Q q 0 0 0 rg BT 428.62 670.05 Td (Such ) Tj ET Q q 0 0 0 rg BT 451.10 670.05 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 519.12 670.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 563.81 670.05 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 658.05 Td (based ) Tj ET Q q 0 0 0 rg BT 61.74 658.05 Td (on ) Tj ET Q q 0 0 0 rg BT 74.70 658.05 Td (current ) Tj ET Q q 0 0 0 rg BT 105.99 658.05 Td (expectations ) Tj ET Q q 0 0 0 rg BT 158.94 658.05 Td (and ) Tj ET Q q 0 0 0 rg BT 176.34 658.05 Td (involve ) Tj ET Q q 0 0 0 rg BT 209.30 658.05 Td (inherent ) Tj ET Q q 0 0 0 rg BT 245.04 658.05 Td (risks ) Tj ET Q q 0 0 0 rg BT 266.90 658.05 Td (and ) Tj ET Q q 0 0 0 rg BT 284.30 658.05 Td (uncertainties, ) Tj ET Q q 0 0 0 rg BT 340.86 658.05 Td (including ) Tj ET Q q 0 0 0 rg BT 381.60 658.05 Td (factors ) Tj ET Q q 0 0 0 rg BT 411.77 658.05 Td (that ) Tj ET Q q 0 0 0 rg BT 429.74 658.05 Td (could ) Tj ET Q q 0 0 0 rg BT 454.92 658.05 Td (delay) Tj ET Q q 0 0 0 rg BT 475.93 658.05 Td (, ) Tj ET Q q 0 0 0 rg BT 481.40 658.05 Td (divert ) Tj ET Q q 0 0 0 rg BT 507.69 658.05 Td (or ) Tj ET Q q 0 0 0 rg BT 518.99 658.05 Td (change ) Tj ET Q q 0 0 0 rg BT 550.27 658.05 Td (any ) Tj ET Q q 0 0 0 rg BT 567.68 658.05 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 646.05 Td (them, ) Tj ET Q q 0 0 0 rg BT 61.52 646.05 Td (and ) Tj ET Q q 0 0 0 rg BT 78.99 646.05 Td (could ) Tj ET Q q 0 0 0 rg BT 104.24 646.05 Td (cause ) Tj ET Q q 0 0 0 rg BT 129.47 646.05 Td (actual ) Tj ET Q q 0 0 0 rg BT 156.37 646.05 Td (outcomes ) Tj ET Q q 0 0 0 rg BT 197.73 646.05 Td (to ) Tj ET Q q 0 0 0 rg BT 208.53 646.05 Td (dif) Tj ET Q q 0 0 0 rg BT 219.46 646.05 Td (fer ) Tj ET Q q 0 0 0 rg BT 233.59 646.05 Td (materially ) Tj ET Q q 0 0 0 rg BT 277.16 646.05 Td (from ) Tj ET Q q 0 0 0 rg BT 299.62 646.05 Td (current ) Tj ET Q q 0 0 0 rg BT 330.97 646.05 Td (expectations. ) Tj ET Q q 0 0 0 rg BT 386.26 646.05 Td (These ) Tj ET Q q 0 0 0 rg BT 413.16 646.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 458.40 646.05 Td (are ) Tj ET Q q 0 0 0 rg BT 473.64 646.05 Td (likely ) Tj ET Q q 0 0 0 rg BT 499.44 646.05 Td (to ) Tj ET Q q 0 0 0 rg BT 510.25 646.05 Td (relate ) Tj ET Q q 0 0 0 rg BT 535.48 646.05 Td (to, ) Tj ET Q q 0 0 0 rg BT 548.79 646.05 Td (among ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 634.05 Td (other ) Tj ET Q q 0 0 0 rg BT 58.78 634.05 Td (things, ) Tj ET Q q 0 0 0 rg BT 87.95 634.05 Td (our ) Tj ET Q q 0 0 0 rg BT 103.51 634.05 Td (goals, ) Tj ET Q q 0 0 0 rg BT 129.35 634.05 Td (plans ) Tj ET Q q 0 0 0 rg BT 152.69 634.05 Td (and ) Tj ET Q q 0 0 0 rg BT 169.35 634.05 Td (projections ) Tj ET Q q 0 0 0 rg BT 216.02 634.05 Td (regarding ) Tj ET Q q 0 0 0 rg BT 256.56 634.05 Td (our ) Tj ET Q q 0 0 0 rg BT 272.12 634.05 Td (financial ) Tj ET Q q 0 0 0 rg BT 309.33 634.05 Td (position, ) Tj ET Q q 0 0 0 rg BT 346.29 634.05 Td (results ) Tj ET Q q 0 0 0 rg BT 374.62 634.05 Td (of ) Tj ET Q q 0 0 0 rg BT 385.18 634.05 Td (operations, ) Tj ET Q q 0 0 0 rg BT 431.57 634.05 Td (cash ) Tj ET Q q 0 0 0 rg BT 451.56 634.05 Td (flows, ) Tj ET Q q 0 0 0 rg BT 478.51 634.05 Td (market ) Tj ET Q q 0 0 0 rg BT 508.51 634.05 Td (position, ) Tj ET Q q 0 0 0 rg BT 545.46 634.05 Td (product ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 622.05 Td (development, ) Tj ET Q q 0 0 0 rg BT 92.72 622.05 Td (product ) Tj ET Q q 0 0 0 rg BT 125.84 622.05 Td (approvals, ) Tj ET Q q 0 0 0 rg BT 169.79 622.05 Td (sales ) Tj ET Q q 0 0 0 rg BT 191.80 622.05 Td (ef) Tj ET Q q 0 0 0 rg BT 199.38 622.05 Td (forts, ) Tj ET Q q 0 0 0 rg BT 222.78 622.05 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 263.95 622.05 Td (performance ) Tj ET Q q 0 0 0 rg BT 317.05 622.05 Td (or ) Tj ET Q q 0 0 0 rg BT 327.95 622.05 Td (results ) Tj ET Q q 0 0 0 rg BT 356.63 622.05 Td (of ) Tj ET Q q 0 0 0 rg BT 367.53 622.05 Td (current ) Tj ET Q q 0 0 0 rg BT 398.41 622.05 Td (and ) Tj ET Q q 0 0 0 rg BT 415.42 622.05 Td (anticipated ) Tj ET Q q 0 0 0 rg BT 461.86 622.05 Td (products ) Tj ET Q q 0 0 0 rg BT 498.87 622.05 Td (and ) Tj ET Q q 0 0 0 rg BT 515.88 622.05 Td (the ) Tj ET Q q 0 0 0 rg BT 530.67 622.05 Td (outcome ) Tj ET Q q 0 0 0 rg BT 567.67 622.05 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 610.05 Td (contingencies ) Tj ET Q q 0 0 0 rg BT 93.97 610.05 Td (such ) Tj ET Q q 0 0 0 rg BT 115.29 610.05 Td (as ) Tj ET Q q 0 0 0 rg BT 126.61 610.05 Td (legal ) Tj ET Q q 0 0 0 rg BT 149.03 610.05 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 200.33 610.05 Td (and ) Tj ET Q q 0 0 0 rg BT 217.76 610.05 Td (financial ) Tj ET Q q 0 0 0 rg BT 255.73 610.05 Td (results, ) Tj ET Q q 0 0 0 rg BT 287.32 610.05 Td (which ) Tj ET Q q 0 0 0 rg BT 314.75 610.05 Td (are ) Tj ET Q q 0 0 0 rg BT 329.95 610.05 Td (based ) Tj ET Q q 0 0 0 rg BT 355.70 610.05 Td (on ) Tj ET Q q 0 0 0 rg BT 368.69 610.05 Td (current ) Tj ET Q q 0 0 0 rg BT 399.99 610.05 Td (expectations ) Tj ET Q q 0 0 0 rg BT 452.96 610.05 Td (that ) Tj ET Q q 0 0 0 rg BT 470.95 610.05 Td (involve ) Tj ET Q q 0 0 0 rg BT 503.93 610.05 Td (inherent ) Tj ET Q q 0 0 0 rg BT 539.68 610.05 Td (risks ) Tj ET Q q 0 0 0 rg BT 561.56 610.05 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 598.05 Td (uncertainties, ) Tj ET Q q 0 0 0 rg BT 92.73 598.05 Td (including ) Tj ET Q q 0 0 0 rg BT 133.65 598.05 Td (internal ) Tj ET Q q 0 0 0 rg BT 167.34 598.05 Td (or ) Tj ET Q q 0 0 0 rg BT 178.82 598.05 Td (external ) Tj ET Q q 0 0 0 rg BT 214.17 598.05 Td (factors ) Tj ET Q q 0 0 0 rg BT 244.52 598.05 Td (that ) Tj ET Q q 0 0 0 rg BT 262.66 598.05 Td (could ) Tj ET Q q 0 0 0 rg BT 288.02 598.05 Td (delay) Tj ET Q q 0 0 0 rg BT 309.03 598.05 Td (, ) Tj ET Q q 0 0 0 rg BT 314.68 598.05 Td (divert ) Tj ET Q q 0 0 0 rg BT 341.15 598.05 Td (or ) Tj ET Q q 0 0 0 rg BT 352.62 598.05 Td (change ) Tj ET Q q 0 0 0 rg BT 384.08 598.05 Td (any ) Tj ET Q q 0 0 0 rg BT 401.67 598.05 Td (of ) Tj ET Q q 0 0 0 rg BT 413.14 598.05 Td (them ) Tj ET Q q 0 0 0 rg BT 436.29 598.05 Td (in ) Tj ET Q q 0 0 0 rg BT 447.21 598.05 Td (the ) Tj ET Q q 0 0 0 rg BT 462.57 598.05 Td (next ) Tj ET Q q 0 0 0 rg BT 482.94 598.05 Td (several ) Tj ET Q q 0 0 0 rg BT 514.40 598.05 Td (years. ) Tj ET Q q 0 0 0 rg BT 540.91 598.05 Td (W) Tj ET Q q 0 0 0 rg BT 549.55 598.05 Td (e ) Tj ET Q q 0 0 0 rg BT 557.14 598.05 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 586.05 Td (included ) Tj ET Q q 0 0 0 rg BT 72.69 586.05 Td (important ) Tj ET Q q 0 0 0 rg BT 113.83 586.05 Td (factors ) Tj ET Q q 0 0 0 rg BT 143.29 586.05 Td (in ) Tj ET Q q 0 0 0 rg BT 153.32 586.05 Td (the ) Tj ET Q q 0 0 0 rg BT 167.80 586.05 Td (cautionary ) Tj ET Q q 0 0 0 rg BT 212.25 586.05 Td (statements ) Tj ET Q q 0 0 0 rg BT 256.72 586.05 Td (included ) Tj ET Q q 0 0 0 rg BT 293.41 586.05 Td (in ) Tj ET Q q 0 0 0 rg BT 303.45 586.05 Td (this ) Tj ET Q q 0 0 0 rg BT 319.65 586.05 Td (Annual ) Tj ET Q q 0 0 0 rg BT 351.35 586.05 Td (Report ) Tj ET Q q 0 0 0 rg BT 380.82 586.05 Td (on ) Tj ET Q q 0 0 0 rg BT 393.08 586.05 Td (Form ) Tj ET Q q 0 0 0 rg BT 417.00 586.05 Td (10-K, ) Tj ET Q q 0 0 0 rg BT 442.31 586.05 Td (particularly ) Tj ET Q q 0 0 0 rg BT 490.65 586.05 Td (under ) Tj ET Q q 0 0 0 rg BT 515.68 586.05 Td (“Item ) Tj ET Q q 0 0 0 rg BT 540.70 586.05 Td (1A. ) Tj ET Q q 0 0 0 rg BT 557.67 586.05 Td (Risk ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 574.05 Td (Factors,” ) Tj ET Q q 0 0 0 rg BT 74.88 574.05 Td (that ) Tj ET Q q 0 0 0 rg BT 92.37 574.05 Td (we ) Tj ET Q q 0 0 0 rg BT 106.53 574.05 Td (believe ) Tj ET Q q 0 0 0 rg BT 137.90 574.05 Td (could ) Tj ET Q q 0 0 0 rg BT 162.62 574.05 Td (cause ) Tj ET Q q 0 0 0 rg BT 187.33 574.05 Td (actual ) Tj ET Q q 0 0 0 rg BT 213.70 574.05 Td (results ) Tj ET Q q 0 0 0 rg BT 242.31 574.05 Td (to ) Tj ET Q q 0 0 0 rg BT 252.59 574.05 Td (dif) Tj ET Q q 0 0 0 rg BT 263.51 574.05 Td (fer ) Tj ET Q q 0 0 0 rg BT 277.11 574.05 Td (materially ) Tj ET Q q 0 0 0 rg BT 320.15 574.05 Td (from ) Tj ET Q q 0 0 0 rg BT 342.09 574.05 Td (any ) Tj ET Q q 0 0 0 rg BT 359.03 574.05 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 427.06 574.05 Td (statement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 554.85 Td (Although ) Tj ET Q q 0 0 0 rg BT 76.62 554.85 Td (we ) Tj ET Q q 0 0 0 rg BT 91.12 554.85 Td (believe ) Tj ET Q q 0 0 0 rg BT 122.84 554.85 Td (we ) Tj ET Q q 0 0 0 rg BT 137.34 554.85 Td (have ) Tj ET Q q 0 0 0 rg BT 159.06 554.85 Td (been ) Tj ET Q q 0 0 0 rg BT 180.78 554.85 Td (prudent ) Tj ET Q q 0 0 0 rg BT 214.16 554.85 Td (in ) Tj ET Q q 0 0 0 rg BT 224.78 554.85 Td (our ) Tj ET Q q 0 0 0 rg BT 240.96 554.85 Td (plans ) Tj ET Q q 0 0 0 rg BT 264.91 554.85 Td (and ) Tj ET Q q 0 0 0 rg BT 282.19 554.85 Td (assumptions, ) Tj ET Q q 0 0 0 rg BT 336.98 554.85 Td (no ) Tj ET Q q 0 0 0 rg BT 349.82 554.85 Td (assurance ) Tj ET Q q 0 0 0 rg BT 391.53 554.85 Td (can ) Tj ET Q q 0 0 0 rg BT 408.25 554.85 Td (be ) Tj ET Q q 0 0 0 rg BT 420.53 554.85 Td (given ) Tj ET Q q 0 0 0 rg BT 445.58 554.85 Td (that ) Tj ET Q q 0 0 0 rg BT 463.42 554.85 Td (any ) Tj ET Q q 0 0 0 rg BT 480.70 554.85 Td (goal ) Tj ET Q q 0 0 0 rg BT 500.76 554.85 Td (or ) Tj ET Q q 0 0 0 rg BT 511.93 554.85 Td (plan ) Tj ET Q q 0 0 0 rg BT 531.99 554.85 Td (set ) Tj ET Q q 0 0 0 rg BT 545.94 554.85 Td (forth ) Tj ET Q q 0 0 0 rg BT 568.22 554.85 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 542.85 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 103.81 542.85 Td (statements ) Tj ET Q q 0 0 0 rg BT 148.30 542.85 Td (can ) Tj ET Q q 0 0 0 rg BT 164.46 542.85 Td (be ) Tj ET Q q 0 0 0 rg BT 176.18 542.85 Td (achieved ) Tj ET Q q 0 0 0 rg BT 213.99 542.85 Td (and ) Tj ET Q q 0 0 0 rg BT 230.70 542.85 Td (readers ) Tj ET Q q 0 0 0 rg BT 261.85 542.85 Td (are ) Tj ET Q q 0 0 0 rg BT 276.33 542.85 Td (cautioned ) Tj ET Q q 0 0 0 rg BT 317.48 542.85 Td (not ) Tj ET Q q 0 0 0 rg BT 332.54 542.85 Td (to ) Tj ET Q q 0 0 0 rg BT 342.59 542.85 Td (place ) Tj ET Q q 0 0 0 rg BT 365.97 542.85 Td (undue ) Tj ET Q q 0 0 0 rg BT 392.68 542.85 Td (reliance ) Tj ET Q q 0 0 0 rg BT 426.60 542.85 Td (on ) Tj ET Q q 0 0 0 rg BT 438.88 542.85 Td (such ) Tj ET Q q 0 0 0 rg BT 459.49 542.85 Td (statements, ) Tj ET Q q 0 0 0 rg BT 506.48 542.85 Td (which ) Tj ET Q q 0 0 0 rg BT 533.19 542.85 Td (speak ) Tj ET Q q 0 0 0 rg BT 558.24 542.85 Td (only ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 530.85 Td (as ) Tj ET Q q 0 0 0 rg BT 47.81 530.85 Td (of ) Tj ET Q q 0 0 0 rg BT 59.63 530.85 Td (the ) Tj ET Q q 0 0 0 rg BT 75.33 530.85 Td (date ) Tj ET Q q 0 0 0 rg BT 95.47 530.85 Td (made. ) Tj ET Q q 0 0 0 rg BT 122.85 530.85 Td (W) Tj ET Q q 0 0 0 rg BT 131.49 530.85 Td (e ) Tj ET Q q 0 0 0 rg BT 139.42 530.85 Td (undertake ) Tj ET Q q 0 0 0 rg BT 182.32 530.85 Td (no ) Tj ET Q q 0 0 0 rg BT 195.81 530.85 Td (obligation ) Tj ET Q q 0 0 0 rg BT 239.84 530.85 Td (to ) Tj ET Q q 0 0 0 rg BT 251.10 530.85 Td (release ) Tj ET Q q 0 0 0 rg BT 282.34 530.85 Td (publicly ) Tj ET Q q 0 0 0 rg BT 318.60 530.85 Td (any ) Tj ET Q q 0 0 0 rg BT 336.52 530.85 Td (revisions ) Tj ET Q q 0 0 0 rg BT 376.11 530.85 Td (to ) Tj ET Q q 0 0 0 rg BT 387.38 530.85 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 456.40 530.85 Td (statements ) Tj ET Q q 0 0 0 rg BT 502.09 530.85 Td (as ) Tj ET Q q 0 0 0 rg BT 513.91 530.85 Td (a ) Tj ET Q q 0 0 0 rg BT 521.83 530.85 Td (result ) Tj ET Q q 0 0 0 rg BT 547.53 530.85 Td (of ) Tj ET Q q 0 0 0 rg BT 559.34 530.85 Td (new ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 518.85 Td (information, ) Tj ET Q q 0 0 0 rg BT 88.21 518.85 Td (future ) Tj ET Q q 0 0 0 rg BT 114.59 518.85 Td (events ) Tj ET Q q 0 0 0 rg BT 142.64 518.85 Td (or ) Tj ET Q q 0 0 0 rg BT 153.47 518.85 Td (otherwise.) Tj ET Q endstream endobj 113 0 obj <> endobj 114 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (56) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 746.23 Td (Item 7A.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 746.23 Td (QUANTIT) Tj ET Q q 0 0 0 rg BT 140.93 746.23 Td (A) Tj ET Q q 0 0 0 rg BT 147.41 746.23 Td (TIVE ) Tj ET Q q 0 0 0 rg BT 173.81 746.23 Td (AND QUALIT) Tj ET Q q 0 0 0 rg BT 236.69 746.23 Td (A) Tj ET Q q 0 0 0 rg BT 243.17 746.23 Td (TIVE DISCLOSURES ) Tj ET Q q 0 0 0 rg BT 342.65 746.23 Td (ABOUT) Tj ET Q q 0 0 0 rg BT 378.03 746.23 Td ( MARKET) Tj ET Q q 0 0 0 rg BT 425.35 746.23 Td ( RISK.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 722.80 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 722.80 Td (e ) Tj ET Q q 0 0 0 rg BT 50.61 722.80 Td (are ) Tj ET Q q 0 0 0 rg BT 64.34 722.80 Td (exposed ) Tj ET Q q 0 0 0 rg BT 98.64 722.80 Td (to ) Tj ET Q q 0 0 0 rg BT 107.95 722.80 Td (market ) Tj ET Q q 0 0 0 rg BT 137.25 722.80 Td (risk ) Tj ET Q q 0 0 0 rg BT 153.78 722.80 Td (resulting ) Tj ET Q q 0 0 0 rg BT 190.30 722.80 Td (from ) Tj ET Q q 0 0 0 rg BT 211.27 722.80 Td (changes ) Tj ET Q q 0 0 0 rg BT 245.01 722.80 Td (in ) Tj ET Q q 0 0 0 rg BT 254.32 722.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 290.83 722.80 Td (exchange ) Tj ET Q q 0 0 0 rg BT 330.11 722.80 Td (rates ) Tj ET Q q 0 0 0 rg BT 350.52 722.80 Td (and ) Tj ET Q q 0 0 0 rg BT 366.49 722.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 397.45 722.80 Td (rates. ) Tj ET Q q 0 0 0 rg BT 420.36 722.80 Td (Certain ) Tj ET Q q 0 0 0 rg BT 451.32 722.80 Td (derivative ) Tj ET Q q 0 0 0 rg BT 492.84 722.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 529.35 722.80 Td (instruments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 710.80 Td (are ) Tj ET Q q 0 0 0 rg BT 50.39 710.80 Td (used ) Tj ET Q q 0 0 0 rg BT 70.90 710.80 Td (when ) Tj ET Q q 0 0 0 rg BT 94.73 710.80 Td (available ) Tj ET Q q 0 0 0 rg BT 133.00 710.80 Td (on ) Tj ET Q q 0 0 0 rg BT 145.18 710.80 Td (a ) Tj ET Q q 0 0 0 rg BT 151.80 710.80 Td (cost-ef) Tj ET Q q 0 0 0 rg BT 178.83 710.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 208.21 710.80 Td (basis ) Tj ET Q q 0 0 0 rg BT 230.39 710.80 Td (to ) Tj ET Q q 0 0 0 rg BT 240.34 710.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 266.40 710.80 Td (our ) Tj ET Q q 0 0 0 rg BT 281.91 710.80 Td (underlying ) Tj ET Q q 0 0 0 rg BT 327.41 710.80 Td (economic ) Tj ET Q q 0 0 0 rg BT 368.47 710.80 Td (exposure. ) Tj ET Q q 0 0 0 rg BT 408.76 710.80 Td (All ) Tj ET Q q 0 0 0 rg BT 423.72 710.80 Td (of ) Tj ET Q q 0 0 0 rg BT 434.23 710.80 Td (our ) Tj ET Q q 0 0 0 rg BT 449.74 710.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 486.90 710.80 Td (instruments, ) Tj ET Q q 0 0 0 rg BT 538.24 710.80 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 698.80 Td (derivatives, ) Tj ET Q q 0 0 0 rg BT 83.83 698.80 Td (are ) Tj ET Q q 0 0 0 rg BT 97.50 698.80 Td (subject ) Tj ET Q q 0 0 0 rg BT 127.29 698.80 Td (to ) Tj ET Q q 0 0 0 rg BT 136.53 698.80 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 188.53 698.80 Td (credit ) Tj ET Q q 0 0 0 rg BT 212.75 698.80 Td (risk ) Tj ET Q q 0 0 0 rg BT 229.22 698.80 Td (considered ) Tj ET Q q 0 0 0 rg BT 273.99 698.80 Td (as ) Tj ET Q q 0 0 0 rg BT 283.79 698.80 Td (part ) Tj ET Q q 0 0 0 rg BT 300.79 698.80 Td (of ) Tj ET Q q 0 0 0 rg BT 310.59 698.80 Td (the ) Tj ET Q q 0 0 0 rg BT 324.27 698.80 Td (overall ) Tj ET Q q 0 0 0 rg BT 353.49 698.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 368.83 698.80 Td (value ) Tj ET Q q 0 0 0 rg BT 391.95 698.80 Td (measurement. ) Tj ET Q q 0 0 0 rg BT 449.22 698.80 Td (Derivative ) Tj ET Q q 0 0 0 rg BT 492.89 698.80 Td (financial ) Tj ET Q q 0 0 0 rg BT 529.33 698.80 Td (instruments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 686.80 Td (are ) Tj ET Q q 0 0 0 rg BT 50.71 686.80 Td (not ) Tj ET Q q 0 0 0 rg BT 65.99 686.80 Td (used ) Tj ET Q q 0 0 0 rg BT 86.82 686.80 Td (for ) Tj ET Q q 0 0 0 rg BT 100.98 686.80 Td (trading ) Tj ET Q q 0 0 0 rg BT 131.80 686.80 Td (purposes.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 667.60 Td (For) Tj ET Q q 0 0 0 rg BT 51.37 667.60 Td (eign Exchange Risk) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 648.40 Td (Significant ) Tj ET Q q 0 0 0 rg BT 82.47 648.40 Td (amounts ) Tj ET Q q 0 0 0 rg BT 118.95 648.40 Td (of ) Tj ET Q q 0 0 0 rg BT 129.88 648.40 Td (our ) Tj ET Q q 0 0 0 rg BT 145.80 648.40 Td (revenues, ) Tj ET Q q 0 0 0 rg BT 186.43 648.40 Td (earnings ) Tj ET Q q 0 0 0 rg BT 222.90 648.40 Td (and ) Tj ET Q q 0 0 0 rg BT 239.93 648.40 Td (cash ) Tj ET Q q 0 0 0 rg BT 260.29 648.40 Td (flow ) Tj ET Q q 0 0 0 rg BT 281.21 648.40 Td (are ) Tj ET Q q 0 0 0 rg BT 296.01 648.40 Td (exposed ) Tj ET Q q 0 0 0 rg BT 331.38 648.40 Td (to ) Tj ET Q q 0 0 0 rg BT 341.75 648.40 Td (changes ) Tj ET Q q 0 0 0 rg BT 376.55 648.40 Td (in ) Tj ET Q q 0 0 0 rg BT 386.92 648.40 Td (foreign ) Tj ET Q q 0 0 0 rg BT 418.39 648.40 Td (currency ) Tj ET Q q 0 0 0 rg BT 455.96 648.40 Td (rates. ) Tj ET Q q 0 0 0 rg BT 479.93 648.40 Td (Our ) Tj ET Q q 0 0 0 rg BT 498.07 648.40 Td (primary ) Tj ET Q q 0 0 0 rg BT 532.32 648.40 Td (net ) Tj ET Q q 0 0 0 rg BT 547.13 648.40 Td (foreign ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 636.40 Td (currency ) Tj ET Q q 0 0 0 rg BT 74.21 636.40 Td (translation ) Tj ET Q q 0 0 0 rg BT 119.66 636.40 Td (exposures ) Tj ET Q q 0 0 0 rg BT 162.89 636.40 Td (are ) Tj ET Q q 0 0 0 rg BT 178.33 636.40 Td (the ) Tj ET Q q 0 0 0 rg BT 193.79 636.40 Td (euro ) Tj ET Q q 0 0 0 rg BT 214.79 636.40 Td (and ) Tj ET Q q 0 0 0 rg BT 232.47 636.40 Td (Japanese ) Tj ET Q q 0 0 0 rg BT 271.24 636.40 Td (yen. ) Tj ET Q q 0 0 0 rg BT 291.42 636.40 Td (Foreign ) Tj ET Q q 0 0 0 rg BT 325.77 636.40 Td (currency ) Tj ET Q q 0 0 0 rg BT 363.98 636.40 Td (forward ) Tj ET Q q 0 0 0 rg BT 398.87 636.40 Td (contracts ) Tj ET Q q 0 0 0 rg BT 438.20 636.40 Td (are ) Tj ET Q q 0 0 0 rg BT 453.64 636.40 Td (used ) Tj ET Q q 0 0 0 rg BT 475.21 636.40 Td (to ) Tj ET Q q 0 0 0 rg BT 486.22 636.40 Td (manage ) Tj ET Q q 0 0 0 rg BT 520.56 636.40 Td (risk ) Tj ET Q q 0 0 0 rg BT 538.79 636.40 Td (primarily ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 624.40 Td (arising ) Tj ET Q q 0 0 0 rg BT 66.40 624.40 Td (from ) Tj ET Q q 0 0 0 rg BT 89.02 624.40 Td (certain ) Tj ET Q q 0 0 0 rg BT 119.40 624.40 Td (intercompany ) Tj ET Q q 0 0 0 rg BT 177.56 624.40 Td (purchase ) Tj ET Q q 0 0 0 rg BT 216.28 624.40 Td (transactions; ) Tj ET Q q 0 0 0 rg BT 270.00 624.40 Td (we ) Tj ET Q q 0 0 0 rg BT 284.85 624.40 Td (are ) Tj ET Q q 0 0 0 rg BT 300.23 624.40 Td (also ) Tj ET Q q 0 0 0 rg BT 319.52 624.40 Td (exposed ) Tj ET Q q 0 0 0 rg BT 355.47 624.40 Td (to ) Tj ET Q q 0 0 0 rg BT 366.43 624.40 Td (foreign ) Tj ET Q q 0 0 0 rg BT 398.49 624.40 Td (exchange ) Tj ET Q q 0 0 0 rg BT 439.43 624.40 Td (transaction ) Tj ET Q q 0 0 0 rg BT 486.48 624.40 Td (risk ) Tj ET Q q 0 0 0 rg BT 504.66 624.40 Td (arising ) Tj ET Q q 0 0 0 rg BT 535.06 624.40 Td (from ) Tj ET Q q 0 0 0 rg BT 557.68 624.40 Td (non-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 612.40 Td (functional ) Tj ET Q q 0 0 0 rg BT 78.50 612.40 Td (currency ) Tj ET Q q 0 0 0 rg BT 115.43 612.40 Td (denominated ) Tj ET Q q 0 0 0 rg BT 169.04 612.40 Td (assets ) Tj ET Q q 0 0 0 rg BT 194.33 612.40 Td (and ) Tj ET Q q 0 0 0 rg BT 210.72 612.40 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 249.90 612.40 Td (and ) Tj ET Q q 0 0 0 rg BT 266.29 612.40 Td (earnings ) Tj ET Q q 0 0 0 rg BT 302.13 612.40 Td (denominated ) Tj ET Q q 0 0 0 rg BT 355.73 612.40 Td (in ) Tj ET Q q 0 0 0 rg BT 365.47 612.40 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 403.54 612.40 Td (dollar ) Tj ET Q q 0 0 0 rg BT 428.82 612.40 Td (currencies. ) Tj ET Q q 0 0 0 rg BT 474.36 612.40 Td (Foreign ) Tj ET Q q 0 0 0 rg BT 507.43 612.40 Td (currency ) Tj ET Q q 0 0 0 rg BT 544.36 612.40 Td (forward ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 600.40 Td (contracts ) Tj ET Q q 0 0 0 rg BT 74.59 600.40 Td (are ) Tj ET Q q 0 0 0 rg BT 89.30 600.40 Td (used ) Tj ET Q q 0 0 0 rg BT 110.13 600.40 Td (to ) Tj ET Q q 0 0 0 rg BT 120.41 600.40 Td (of) Tj ET Q q 0 0 0 rg BT 128.56 600.40 Td (fset ) Tj ET Q q 0 0 0 rg BT 145.50 600.40 Td (these ) Tj ET Q q 0 0 0 rg BT 168.54 600.40 Td (exposures ) Tj ET Q q 0 0 0 rg BT 211.03 600.40 Td (but ) Tj ET Q q 0 0 0 rg BT 226.31 600.40 Td (are ) Tj ET Q q 0 0 0 rg BT 241.02 600.40 Td (not ) Tj ET Q q 0 0 0 rg BT 256.30 600.40 Td (designated ) Tj ET Q q 0 0 0 rg BT 301.56 600.40 Td (as ) Tj ET Q q 0 0 0 rg BT 312.39 600.40 Td (hedges.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.20 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 581.20 Td (e ) Tj ET Q q 0 0 0 rg BT 51.77 581.20 Td (estimate ) Tj ET Q q 0 0 0 rg BT 87.78 581.20 Td (that ) Tj ET Q q 0 0 0 rg BT 105.47 581.20 Td (a ) Tj ET Q q 0 0 0 rg BT 112.60 581.20 Td (10% ) Tj ET Q q 0 0 0 rg BT 133.62 581.20 Td (appreciation ) Tj ET Q q 0 0 0 rg BT 185.74 581.20 Td (in ) Tj ET Q q 0 0 0 rg BT 196.21 581.20 Td (the ) Tj ET Q q 0 0 0 rg BT 211.12 581.20 Td (underlying ) Tj ET Q q 0 0 0 rg BT 257.14 581.20 Td (currencies ) Tj ET Q q 0 0 0 rg BT 300.91 581.20 Td (being ) Tj ET Q q 0 0 0 rg BT 325.82 581.20 Td (hedged ) Tj ET Q q 0 0 0 rg BT 357.39 581.20 Td (from ) Tj ET Q q 0 0 0 rg BT 379.52 581.20 Td (their ) Tj ET Q q 0 0 0 rg BT 400.54 581.20 Td (levels ) Tj ET Q q 0 0 0 rg BT 426.56 581.20 Td (against ) Tj ET Q q 0 0 0 rg BT 457.58 581.20 Td (the ) Tj ET Q q 0 0 0 rg BT 472.49 581.20 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 492.96 581.20 Td (dollar ) Tj ET Q q 0 0 0 rg BT 518.98 581.20 Td (\(with ) Tj ET Q q 0 0 0 rg BT 542.78 581.20 Td (all ) Tj ET Q q 0 0 0 rg BT 555.47 581.20 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.20 Td (variables ) Tj ET Q q 0 0 0 rg BT 75.18 569.20 Td (held ) Tj ET Q q 0 0 0 rg BT 95.48 569.20 Td (constant\) ) Tj ET Q q 0 0 0 rg BT 135.21 569.20 Td (would ) Tj ET Q q 0 0 0 rg BT 163.30 569.20 Td (decrease ) Tj ET Q q 0 0 0 rg BT 200.79 569.20 Td (the ) Tj ET Q q 0 0 0 rg BT 216.09 569.20 Td (fair ) Tj ET Q q 0 0 0 rg BT 233.05 569.20 Td (value ) Tj ET Q q 0 0 0 rg BT 257.79 569.20 Td (of ) Tj ET Q q 0 0 0 rg BT 269.20 569.20 Td (foreign ) Tj ET Q q 0 0 0 rg BT 301.16 569.20 Td (exchange ) Tj ET Q q 0 0 0 rg BT 342.00 569.20 Td (forward ) Tj ET Q q 0 0 0 rg BT 376.73 569.20 Td (contracts ) Tj ET Q q 0 0 0 rg BT 415.91 569.20 Td (by ) Tj ET Q q 0 0 0 rg BT 428.99 569.20 Td ($175 ) Tj ET Q q 0 0 0 rg BT 452.07 569.20 Td (million ) Tj ET Q q 0 0 0 rg BT 484.05 569.20 Td (at ) Tj ET Q q 0 0 0 rg BT 494.35 569.20 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.51 569.20 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.51 569.20 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.20 Td (reducing ) Tj ET Q q 0 0 0 rg BT 73.49 557.20 Td (earnings ) Tj ET Q q 0 0 0 rg BT 109.86 557.20 Td (over ) Tj ET Q q 0 0 0 rg BT 130.13 557.20 Td (the ) Tj ET Q q 0 0 0 rg BT 144.85 557.20 Td (remaining ) Tj ET Q q 0 0 0 rg BT 187.89 557.20 Td (life ) Tj ET Q q 0 0 0 rg BT 203.71 557.20 Td (of ) Tj ET Q q 0 0 0 rg BT 214.54 557.20 Td (the ) Tj ET Q q 0 0 0 rg BT 229.26 557.20 Td (contracts.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 538.00 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 538.00 Td (e ) Tj ET Q q 0 0 0 rg BT 52.07 538.00 Td (are ) Tj ET Q q 0 0 0 rg BT 67.28 538.00 Td (also ) Tj ET Q q 0 0 0 rg BT 86.39 538.00 Td (exposed ) Tj ET Q q 0 0 0 rg BT 122.15 538.00 Td (to ) Tj ET Q q 0 0 0 rg BT 132.93 538.00 Td (translation ) Tj ET Q q 0 0 0 rg BT 178.14 538.00 Td (risk ) Tj ET Q q 0 0 0 rg BT 196.14 538.00 Td (on ) Tj ET Q q 0 0 0 rg BT 209.13 538.00 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 248.25 538.00 Td (dollar) Tj ET Q q 0 0 0 rg BT 271.37 538.00 Td (-denominated ) Tj ET Q q 0 0 0 rg BT 329.35 538.00 Td (net ) Tj ET Q q 0 0 0 rg BT 344.56 538.00 Td (assets. ) Tj ET Q q 0 0 0 rg BT 373.39 538.00 Td (Non-U.S. ) Tj ET Q q 0 0 0 rg BT 414.73 538.00 Td (dollar ) Tj ET Q q 0 0 0 rg BT 441.05 538.00 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 489.60 538.00 Td (are ) Tj ET Q q 0 0 0 rg BT 504.80 538.00 Td (used ) Tj ET Q q 0 0 0 rg BT 526.13 538.00 Td (to ) Tj ET Q q 0 0 0 rg BT 536.91 538.00 Td (hedge ) Tj ET Q q 0 0 0 rg BT 563.78 538.00 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 526.00 Td (foreign ) Tj ET Q q 0 0 0 rg BT 66.54 526.00 Td (currency ) Tj ET Q q 0 0 0 rg BT 103.17 526.00 Td (exposures ) Tj ET Q q 0 0 0 rg BT 144.82 526.00 Td (of ) Tj ET Q q 0 0 0 rg BT 154.81 526.00 Td (our ) Tj ET Q q 0 0 0 rg BT 169.80 526.00 Td (net ) Tj ET Q q 0 0 0 rg BT 183.68 526.00 Td (investment ) Tj ET Q q 0 0 0 rg BT 229.22 526.00 Td (in ) Tj ET Q q 0 0 0 rg BT 238.66 526.00 Td (certain ) Tj ET Q q 0 0 0 rg BT 267.52 526.00 Td (foreign ) Tj ET Q q 0 0 0 rg BT 298.06 526.00 Td (af) Tj ET Q q 0 0 0 rg BT 305.65 526.00 Td (filiates ) Tj ET Q q 0 0 0 rg BT 334.52 526.00 Td (and ) Tj ET Q q 0 0 0 rg BT 350.62 526.00 Td (are ) Tj ET Q q 0 0 0 rg BT 364.49 526.00 Td (designated ) Tj ET Q q 0 0 0 rg BT 408.91 526.00 Td (as ) Tj ET Q q 0 0 0 rg BT 418.90 526.00 Td (hedges ) Tj ET Q q 0 0 0 rg BT 448.33 526.00 Td (of ) Tj ET Q q 0 0 0 rg BT 458.32 526.00 Td (net ) Tj ET Q q 0 0 0 rg BT 472.20 526.00 Td (investments. ) Tj ET Q q 0 0 0 rg BT 524.01 526.00 Td (The ) Tj ET Q q 0 0 0 rg BT 541.22 526.00 Td (ef) Tj ET Q q 0 0 0 rg BT 548.80 526.00 Td (fective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 514.00 Td (portion ) Tj ET Q q 0 0 0 rg BT 67.73 514.00 Td (of ) Tj ET Q q 0 0 0 rg BT 78.91 514.00 Td (foreign ) Tj ET Q q 0 0 0 rg BT 110.63 514.00 Td (exchange ) Tj ET Q q 0 0 0 rg BT 151.23 514.00 Td (gains ) Tj ET Q q 0 0 0 rg BT 175.18 514.00 Td (or ) Tj ET Q q 0 0 0 rg BT 186.36 514.00 Td (losses ) Tj ET Q q 0 0 0 rg BT 213.10 514.00 Td (on ) Tj ET Q q 0 0 0 rg BT 225.94 514.00 Td (these ) Tj ET Q q 0 0 0 rg BT 249.34 514.00 Td (hedges ) Tj ET Q q 0 0 0 rg BT 279.95 514.00 Td (is ) Tj ET Q q 0 0 0 rg BT 289.47 514.00 Td (included ) Tj ET Q q 0 0 0 rg BT 326.75 514.00 Td (in ) Tj ET Q q 0 0 0 rg BT 337.37 514.00 Td (the ) Tj ET Q q 0 0 0 rg BT 352.43 514.00 Td (foreign ) Tj ET Q q 0 0 0 rg BT 384.15 514.00 Td (currency ) Tj ET Q q 0 0 0 rg BT 421.98 514.00 Td (translation ) Tj ET Q q 0 0 0 rg BT 467.03 514.00 Td (component ) Tj ET Q q 0 0 0 rg BT 514.31 514.00 Td (of ) Tj ET Q q 0 0 0 rg BT 525.49 514.00 Td (accumulated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 502.00 Td (other ) Tj ET Q q 0 0 0 rg BT 59.69 502.00 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 123.37 502.00 Td (income/\(loss\). ) Tj ET Q q 0 0 0 rg BT 183.45 502.00 Td (If ) Tj ET Q q 0 0 0 rg BT 193.26 502.00 Td (our ) Tj ET Q q 0 0 0 rg BT 209.74 502.00 Td (net ) Tj ET Q q 0 0 0 rg BT 225.10 502.00 Td (investment ) Tj ET Q q 0 0 0 rg BT 272.13 502.00 Td (decreases ) Tj ET Q q 0 0 0 rg BT 313.58 502.00 Td (below ) Tj ET Q q 0 0 0 rg BT 341.17 502.00 Td (the ) Tj ET Q q 0 0 0 rg BT 356.53 502.00 Td (equivalent ) Tj ET Q q 0 0 0 rg BT 401.33 502.00 Td (value ) Tj ET Q q 0 0 0 rg BT 426.13 502.00 Td (of ) Tj ET Q q 0 0 0 rg BT 437.61 502.00 Td (the ) Tj ET Q q 0 0 0 rg BT 452.97 502.00 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 492.23 502.00 Td (debt ) Tj ET Q q 0 0 0 rg BT 512.60 502.00 Td (borrowings, ) Tj ET Q q 0 0 0 rg BT 563.80 502.00 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 490.00 Td (change ) Tj ET Q q 0 0 0 rg BT 66.88 490.00 Td (in ) Tj ET Q q 0 0 0 rg BT 77.22 490.00 Td (the ) Tj ET Q q 0 0 0 rg BT 92.00 490.00 Td (remeasurement ) Tj ET Q q 0 0 0 rg BT 155.64 490.00 Td (basis ) Tj ET Q q 0 0 0 rg BT 178.21 490.00 Td (of ) Tj ET Q q 0 0 0 rg BT 189.10 490.00 Td (the ) Tj ET Q q 0 0 0 rg BT 203.88 490.00 Td (debt ) Tj ET Q q 0 0 0 rg BT 223.66 490.00 Td (would ) Tj ET Q q 0 0 0 rg BT 251.22 490.00 Td (be ) Tj ET Q q 0 0 0 rg BT 263.23 490.00 Td (subject ) Tj ET Q q 0 0 0 rg BT 294.12 490.00 Td (to ) Tj ET Q q 0 0 0 rg BT 304.46 490.00 Td (recognition ) Tj ET Q q 0 0 0 rg BT 352.56 490.00 Td (in ) Tj ET Q q 0 0 0 rg BT 362.90 490.00 Td (income ) Tj ET Q q 0 0 0 rg BT 394.90 490.00 Td (as ) Tj ET Q q 0 0 0 rg BT 405.79 490.00 Td (changes ) Tj ET Q q 0 0 0 rg BT 440.57 490.00 Td (occur) Tj ET Q q 0 0 0 rg BT 462.22 490.00 Td (. ) Tj ET Q q 0 0 0 rg BT 467.28 490.00 Td (For ) Tj ET Q q 0 0 0 rg BT 483.74 490.00 Td (additional ) Tj ET Q q 0 0 0 rg BT 526.29 490.00 Td (information, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 478.00 Td (refer ) Tj ET Q q 0 0 0 rg BT 57.37 478.00 Td (to ) Tj ET Q q 0 0 0 rg BT 67.65 478.00 Td (“Item ) Tj ET Q q 0 0 0 rg BT 92.91 478.00 Td (8. ) Tj ET Q q 0 0 0 rg BT 102.91 478.00 Td (Financial ) Tj ET Q q 0 0 0 rg BT 142.62 478.00 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 218.44 478.00 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.44 478.00 Td (. ) Tj ET Q q 0 0 0 rg BT 228.44 478.00 Td (Financial ) Tj ET Q q 0 0 0 rg BT 268.15 478.00 Td (Instruments ) Tj ET Q q 0 0 0 rg BT 317.87 478.00 Td (and ) Tj ET Q q 0 0 0 rg BT 334.81 478.00 Td (Fair ) Tj ET Q q 0 0 0 rg BT 353.24 478.00 Td (V) Tj ET Q q 0 0 0 rg BT 359.35 478.00 Td (alue ) Tj ET Q q 0 0 0 rg BT 378.50 478.00 Td (Measurements.”) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 458.80 Td (Inter) Tj ET Q q 0 0 0 rg BT 57.48 458.80 Td (est Rate Risk) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 439.60 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 439.60 Td (e ) Tj ET Q q 0 0 0 rg BT 50.77 439.60 Td (use ) Tj ET Q q 0 0 0 rg BT 65.79 439.60 Td (fixed-to-floating ) Tj ET Q q 0 0 0 rg BT 133.57 439.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 164.69 439.60 Td (rate ) Tj ET Q q 0 0 0 rg BT 181.37 439.60 Td (swap ) Tj ET Q q 0 0 0 rg BT 203.61 439.60 Td (contracts ) Tj ET Q q 0 0 0 rg BT 241.40 439.60 Td (designated ) Tj ET Q q 0 0 0 rg BT 285.85 439.60 Td (as ) Tj ET Q q 0 0 0 rg BT 295.87 439.60 Td (fair ) Tj ET Q q 0 0 0 rg BT 311.44 439.60 Td (value ) Tj ET Q q 0 0 0 rg BT 334.79 439.60 Td (hedges ) Tj ET Q q 0 0 0 rg BT 364.25 439.60 Td (to ) Tj ET Q q 0 0 0 rg BT 373.71 439.60 Td (provide ) Tj ET Q q 0 0 0 rg BT 405.95 439.60 Td (an ) Tj ET Q q 0 0 0 rg BT 417.08 439.60 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 464.30 439.60 Td (balance ) Tj ET Q q 0 0 0 rg BT 496.53 439.60 Td (of ) Tj ET Q q 0 0 0 rg BT 506.55 439.60 Td (fixed ) Tj ET Q q 0 0 0 rg BT 528.79 439.60 Td (and ) Tj ET Q q 0 0 0 rg BT 544.92 439.60 Td (floating ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 427.60 Td (rate ) Tj ET Q q 0 0 0 rg BT 53.59 427.60 Td (debt. ) Tj ET Q q 0 0 0 rg BT 75.71 427.60 Td (W) Tj ET Q q 0 0 0 rg BT 84.35 427.60 Td (e ) Tj ET Q q 0 0 0 rg BT 91.39 427.60 Td (estimate ) Tj ET Q q 0 0 0 rg BT 127.31 427.60 Td (that ) Tj ET Q q 0 0 0 rg BT 144.91 427.60 Td (an ) Tj ET Q q 0 0 0 rg BT 156.94 427.60 Td (increase ) Tj ET Q q 0 0 0 rg BT 192.30 427.60 Td (of ) Tj ET Q q 0 0 0 rg BT 203.23 427.60 Td (100 ) Tj ET Q q 0 0 0 rg BT 220.83 427.60 Td (basis ) Tj ET Q q 0 0 0 rg BT 243.43 427.60 Td (points ) Tj ET Q q 0 0 0 rg BT 270.48 427.60 Td (in ) Tj ET Q q 0 0 0 rg BT 280.86 427.60 Td (short-term ) Tj ET Q q 0 0 0 rg BT 325.11 427.60 Td (or ) Tj ET Q q 0 0 0 rg BT 336.04 427.60 Td (long-term ) Tj ET Q q 0 0 0 rg BT 378.08 427.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 410.11 427.60 Td (rates ) Tj ET Q q 0 0 0 rg BT 431.59 427.60 Td (would ) Tj ET Q q 0 0 0 rg BT 459.19 427.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 496.20 427.60 Td (the ) Tj ET Q q 0 0 0 rg BT 511.02 427.60 Td (fair ) Tj ET Q q 0 0 0 rg BT 527.49 427.60 Td (value ) Tj ET Q q 0 0 0 rg BT 551.75 427.60 Td (of ) Tj ET Q q 0 0 0 rg BT 562.68 427.60 Td (our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 415.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 67.93 415.60 Td (rate ) Tj ET Q q 0 0 0 rg BT 85.42 415.60 Td (swap ) Tj ET Q q 0 0 0 rg BT 108.47 415.60 Td (contracts ) Tj ET Q q 0 0 0 rg BT 147.06 415.60 Td (by ) Tj ET Q q 0 0 0 rg BT 159.56 415.60 Td ($25 ) Tj ET Q q 0 0 0 rg BT 177.06 415.60 Td (million, ) Tj ET Q q 0 0 0 rg BT 210.96 415.60 Td (thereby ) Tj ET Q q 0 0 0 rg BT 243.44 415.60 Td (reducing ) Tj ET Q q 0 0 0 rg BT 280.93 415.60 Td (earnings ) Tj ET Q q 0 0 0 rg BT 317.30 415.60 Td (over ) Tj ET Q q 0 0 0 rg BT 337.57 415.60 Td (the ) Tj ET Q q 0 0 0 rg BT 352.29 415.60 Td (remaining ) Tj ET Q q 0 0 0 rg BT 395.33 415.60 Td (life ) Tj ET Q q 0 0 0 rg BT 411.16 415.60 Td (of ) Tj ET Q q 0 0 0 rg BT 421.99 415.60 Td (the ) Tj ET Q q 0 0 0 rg BT 436.70 415.60 Td (contracts.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 391.60 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 391.60 Td (e ) Tj ET Q q 0 0 0 rg BT 52.30 391.60 Td (estimate ) Tj ET Q q 0 0 0 rg BT 88.85 391.60 Td (that ) Tj ET Q q 0 0 0 rg BT 107.07 391.60 Td (an ) Tj ET Q q 0 0 0 rg BT 119.74 391.60 Td (increase ) Tj ET Q q 0 0 0 rg BT 155.72 391.60 Td (of ) Tj ET Q q 0 0 0 rg BT 167.27 391.60 Td (100 ) Tj ET Q q 0 0 0 rg BT 185.50 391.60 Td (basis ) Tj ET Q q 0 0 0 rg BT 208.73 391.60 Td (points ) Tj ET Q q 0 0 0 rg BT 236.40 391.60 Td (in ) Tj ET Q q 0 0 0 rg BT 247.41 391.60 Td (long-term ) Tj ET Q q 0 0 0 rg BT 290.07 391.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 322.73 391.60 Td (rates ) Tj ET Q q 0 0 0 rg BT 344.83 391.60 Td (would ) Tj ET Q q 0 0 0 rg BT 373.06 391.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 410.70 391.60 Td (the ) Tj ET Q q 0 0 0 rg BT 426.14 391.60 Td (fair ) Tj ET Q q 0 0 0 rg BT 443.24 391.60 Td (value ) Tj ET Q q 0 0 0 rg BT 468.13 391.60 Td (of ) Tj ET Q q 0 0 0 rg BT 479.68 391.60 Td (long-term ) Tj ET Q q 0 0 0 rg BT 522.34 391.60 Td (debt ) Tj ET Q q 0 0 0 rg BT 542.79 391.60 Td (by ) Tj ET Q q 0 0 0 rg BT 556.01 391.60 Td ($569 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 379.60 Td (million. ) Tj ET Q q 0 0 0 rg BT 70.23 379.60 Td (Our ) Tj ET Q q 0 0 0 rg BT 88.63 379.60 Td (marketable ) Tj ET Q q 0 0 0 rg BT 135.88 379.60 Td (securities ) Tj ET Q q 0 0 0 rg BT 176.49 379.60 Td (are ) Tj ET Q q 0 0 0 rg BT 191.54 379.60 Td (subject ) Tj ET Q q 0 0 0 rg BT 222.70 379.60 Td (to ) Tj ET Q q 0 0 0 rg BT 233.32 379.60 Td (changes ) Tj ET Q q 0 0 0 rg BT 268.37 379.60 Td (in ) Tj ET Q q 0 0 0 rg BT 278.99 379.60 Td (fair ) Tj ET Q q 0 0 0 rg BT 295.71 379.60 Td (value ) Tj ET Q q 0 0 0 rg BT 320.20 379.60 Td (as ) Tj ET Q q 0 0 0 rg BT 331.37 379.60 Td (a ) Tj ET Q q 0 0 0 rg BT 338.65 379.60 Td (result ) Tj ET Q q 0 0 0 rg BT 363.71 379.60 Td (of ) Tj ET Q q 0 0 0 rg BT 374.88 379.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 407.16 379.60 Td (rate ) Tj ET Q q 0 0 0 rg BT 424.98 379.60 Td (fluctuations ) Tj ET Q q 0 0 0 rg BT 475.04 379.60 Td (and ) Tj ET Q q 0 0 0 rg BT 492.31 379.60 Td (other ) Tj ET Q q 0 0 0 rg BT 515.70 379.60 Td (market ) Tj ET Q q 0 0 0 rg BT 546.31 379.60 Td (factors. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 367.60 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 367.60 Td (e ) Tj ET Q q 0 0 0 rg BT 51.39 367.60 Td (estimate ) Tj ET Q q 0 0 0 rg BT 87.03 367.60 Td (that ) Tj ET Q q 0 0 0 rg BT 104.34 367.60 Td (an ) Tj ET Q q 0 0 0 rg BT 116.10 367.60 Td (increase ) Tj ET Q q 0 0 0 rg BT 151.17 367.60 Td (of ) Tj ET Q q 0 0 0 rg BT 161.82 367.60 Td (100 ) Tj ET Q q 0 0 0 rg BT 179.13 367.60 Td (basis ) Tj ET Q q 0 0 0 rg BT 201.45 367.60 Td (points ) Tj ET Q q 0 0 0 rg BT 228.21 367.60 Td (in ) Tj ET Q q 0 0 0 rg BT 238.31 367.60 Td (interest ) Tj ET Q q 0 0 0 rg BT 270.06 367.60 Td (rates ) Tj ET Q q 0 0 0 rg BT 291.25 367.60 Td (would ) Tj ET Q q 0 0 0 rg BT 318.57 367.60 Td (decrease ) Tj ET Q q 0 0 0 rg BT 355.30 367.60 Td (the ) Tj ET Q q 0 0 0 rg BT 369.84 367.60 Td (fair ) Tj ET Q q 0 0 0 rg BT 386.03 367.60 Td (value ) Tj ET Q q 0 0 0 rg BT 410.00 367.60 Td (of ) Tj ET Q q 0 0 0 rg BT 420.65 367.60 Td (our ) Tj ET Q q 0 0 0 rg BT 436.30 367.60 Td (debt ) Tj ET Q q 0 0 0 rg BT 455.83 367.60 Td (investments ) Tj ET Q q 0 0 0 rg BT 505.92 367.60 Td (by ) Tj ET Q q 0 0 0 rg BT 518.24 367.60 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 355.60 Td ($70 ) Tj ET Q q 0 0 0 rg BT 53.50 355.60 Td (million.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 336.40 Td (Cr) Tj ET Q q 0 0 0 rg BT 47.48 336.40 Td (edit Risk) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.20 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 317.20 Td (e ) Tj ET Q q 0 0 0 rg BT 51.33 317.20 Td (monitor ) Tj ET Q q 0 0 0 rg BT 85.26 317.20 Td (our ) Tj ET Q q 0 0 0 rg BT 100.85 317.20 Td (investments ) Tj ET Q q 0 0 0 rg BT 150.88 317.20 Td (with ) Tj ET Q q 0 0 0 rg BT 170.91 317.20 Td (counterparties ) Tj ET Q q 0 0 0 rg BT 229.81 317.20 Td (with ) Tj ET Q q 0 0 0 rg BT 249.85 317.20 Td (the ) Tj ET Q q 0 0 0 rg BT 264.33 317.20 Td (objective ) Tj ET Q q 0 0 0 rg BT 303.23 317.20 Td (of ) Tj ET Q q 0 0 0 rg BT 313.82 317.20 Td (minimizing ) Tj ET Q q 0 0 0 rg BT 362.19 317.20 Td (concentrations ) Tj ET Q q 0 0 0 rg BT 422.76 317.20 Td (of ) Tj ET Q q 0 0 0 rg BT 433.35 317.20 Td (credit ) Tj ET Q q 0 0 0 rg BT 458.37 317.20 Td (risk. ) Tj ET Q q 0 0 0 rg BT 478.13 317.20 Td (Our ) Tj ET Q q 0 0 0 rg BT 495.94 317.20 Td (investment ) Tj ET Q q 0 0 0 rg BT 542.08 317.20 Td (policy ) Tj ET Q q 0 0 0 rg BT 569.33 317.20 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.20 Td (to ) Tj ET Q q 0 0 0 rg BT 45.37 305.20 Td (invest ) Tj ET Q q 0 0 0 rg BT 70.85 305.20 Td (only ) Tj ET Q q 0 0 0 rg BT 90.23 305.20 Td (in ) Tj ET Q q 0 0 0 rg BT 99.60 305.20 Td (institutions ) Tj ET Q q 0 0 0 rg BT 145.65 305.20 Td (that ) Tj ET Q q 0 0 0 rg BT 162.24 305.20 Td (meet ) Tj ET Q q 0 0 0 rg BT 183.26 305.20 Td (high ) Tj ET Q q 0 0 0 rg BT 202.64 305.20 Td (credit ) Tj ET Q q 0 0 0 rg BT 226.99 305.20 Td (quality ) Tj ET Q q 0 0 0 rg BT 256.36 305.20 Td (standards ) Tj ET Q q 0 0 0 rg BT 295.72 305.20 Td (and ) Tj ET Q q 0 0 0 rg BT 311.76 305.20 Td (establishes ) Tj ET Q q 0 0 0 rg BT 356.68 305.20 Td (limits ) Tj ET Q q 0 0 0 rg BT 381.05 305.20 Td (on ) Tj ET Q q 0 0 0 rg BT 392.65 305.20 Td (the ) Tj ET Q q 0 0 0 rg BT 406.46 305.20 Td (amount ) Tj ET Q q 0 0 0 rg BT 438.05 305.20 Td (and ) Tj ET Q q 0 0 0 rg BT 454.08 305.20 Td (time ) Tj ET Q q 0 0 0 rg BT 473.45 305.20 Td (to ) Tj ET Q q 0 0 0 rg BT 482.82 305.20 Td (maturity ) Tj ET Q q 0 0 0 rg BT 518.30 305.20 Td (of ) Tj ET Q q 0 0 0 rg BT 528.22 305.20 Td (investments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.20 Td (with ) Tj ET Q q 0 0 0 rg BT 55.95 293.20 Td (any ) Tj ET Q q 0 0 0 rg BT 72.55 293.20 Td (individual ) Tj ET Q q 0 0 0 rg BT 115.27 293.20 Td (counterparty) Tj ET Q q 0 0 0 rg BT 165.16 293.20 Td (. ) Tj ET Q q 0 0 0 rg BT 169.67 293.20 Td (The ) Tj ET Q q 0 0 0 rg BT 187.38 293.20 Td (policy ) Tj ET Q q 0 0 0 rg BT 214.54 293.20 Td (also ) Tj ET Q q 0 0 0 rg BT 232.82 293.20 Td (requires ) Tj ET Q q 0 0 0 rg BT 267.20 293.20 Td (that ) Tj ET Q q 0 0 0 rg BT 284.36 293.20 Td (investments ) Tj ET Q q 0 0 0 rg BT 334.30 293.20 Td (are ) Tj ET Q q 0 0 0 rg BT 348.68 293.20 Td (only ) Tj ET Q q 0 0 0 rg BT 368.62 293.20 Td (entered ) Tj ET Q q 0 0 0 rg BT 400.21 293.20 Td (into ) Tj ET Q q 0 0 0 rg BT 417.94 293.20 Td (with ) Tj ET Q q 0 0 0 rg BT 437.88 293.20 Td (corporate ) Tj ET Q q 0 0 0 rg BT 477.81 293.20 Td (and ) Tj ET Q q 0 0 0 rg BT 494.41 293.20 Td (financial ) Tj ET Q q 0 0 0 rg BT 531.56 293.20 Td (institutions ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.20 Td (that ) Tj ET Q q 0 0 0 rg BT 53.50 281.20 Td (meet ) Tj ET Q q 0 0 0 rg BT 75.43 281.20 Td (high ) Tj ET Q q 0 0 0 rg BT 95.71 281.20 Td (credit ) Tj ET Q q 0 0 0 rg BT 120.97 281.20 Td (quality ) Tj ET Q q 0 0 0 rg BT 151.24 281.20 Td (standards.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 262.00 Td (The ) Tj ET Q q 0 0 0 rg BT 53.25 262.00 Td (use ) Tj ET Q q 0 0 0 rg BT 68.28 262.00 Td (of ) Tj ET Q q 0 0 0 rg BT 78.30 262.00 Td (derivative ) Tj ET Q q 0 0 0 rg BT 119.98 262.00 Td (instruments ) Tj ET Q q 0 0 0 rg BT 168.35 262.00 Td (exposes ) Tj ET Q q 0 0 0 rg BT 201.71 262.00 Td (us ) Tj ET Q q 0 0 0 rg BT 212.30 262.00 Td (to ) Tj ET Q q 0 0 0 rg BT 221.78 262.00 Td (credit ) Tj ET Q q 0 0 0 rg BT 246.24 262.00 Td (risk ) Tj ET Q q 0 0 0 rg BT 262.94 262.00 Td (if ) Tj ET Q q 0 0 0 rg BT 270.75 262.00 Td (the ) Tj ET Q q 0 0 0 rg BT 284.66 262.00 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 336.89 262.00 Td (fails ) Tj ET Q q 0 0 0 rg BT 355.81 262.00 Td (to ) Tj ET Q q 0 0 0 rg BT 365.29 262.00 Td (perform ) Tj ET Q q 0 0 0 rg BT 399.19 262.00 Td (when ) Tj ET Q q 0 0 0 rg BT 422.55 262.00 Td (the ) Tj ET Q q 0 0 0 rg BT 436.47 262.00 Td (fair ) Tj ET Q q 0 0 0 rg BT 452.04 262.00 Td (value ) Tj ET Q q 0 0 0 rg BT 475.40 262.00 Td (of ) Tj ET Q q 0 0 0 rg BT 485.43 262.00 Td (a ) Tj ET Q q 0 0 0 rg BT 491.57 262.00 Td (derivative ) Tj ET Q q 0 0 0 rg BT 533.25 262.00 Td (instrument ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 250.00 Td (contract ) Tj ET Q q 0 0 0 rg BT 71.37 250.00 Td (is ) Tj ET Q q 0 0 0 rg BT 81.20 250.00 Td (positive. ) Tj ET Q q 0 0 0 rg BT 118.53 250.00 Td (If ) Tj ET Q q 0 0 0 rg BT 128.36 250.00 Td (the ) Tj ET Q q 0 0 0 rg BT 143.74 250.00 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 197.44 250.00 Td (fails ) Tj ET Q q 0 0 0 rg BT 217.82 250.00 Td (to ) Tj ET Q q 0 0 0 rg BT 228.77 250.00 Td (perform, ) Tj ET Q q 0 0 0 rg BT 266.64 250.00 Td (collateral ) Tj ET Q q 0 0 0 rg BT 307.00 250.00 Td (is ) Tj ET Q q 0 0 0 rg BT 316.84 250.00 Td (not ) Tj ET Q q 0 0 0 rg BT 332.78 250.00 Td (required ) Tj ET Q q 0 0 0 rg BT 369.26 250.00 Td (by ) Tj ET Q q 0 0 0 rg BT 382.43 250.00 Td (any ) Tj ET Q q 0 0 0 rg BT 400.03 250.00 Td (party ) Tj ET Q q 0 0 0 rg BT 423.74 250.00 Td (whether ) Tj ET Q q 0 0 0 rg BT 459.12 250.00 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 506.15 250.00 Td (are ) Tj ET Q q 0 0 0 rg BT 521.53 250.00 Td (in ) Tj ET Q q 0 0 0 rg BT 532.47 250.00 Td (an ) Tj ET Q q 0 0 0 rg BT 545.07 250.00 Td (asset ) Tj ET Q q 0 0 0 rg BT 567.68 250.00 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 238.00 Td (liability ) Tj ET Q q 0 0 0 rg BT 69.86 238.00 Td (position. ) Tj ET Q q 0 0 0 rg BT 107.13 238.00 Td (W) Tj ET Q q 0 0 0 rg BT 115.77 238.00 Td (e ) Tj ET Q q 0 0 0 rg BT 122.96 238.00 Td (have ) Tj ET Q q 0 0 0 rg BT 144.59 238.00 Td (a ) Tj ET Q q 0 0 0 rg BT 151.77 238.00 Td (policy ) Tj ET Q q 0 0 0 rg BT 179.52 238.00 Td (of ) Tj ET Q q 0 0 0 rg BT 190.60 238.00 Td (diversifying ) Tj ET Q q 0 0 0 rg BT 241.67 238.00 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 288.29 238.00 Td (with ) Tj ET Q q 0 0 0 rg BT 308.82 238.00 Td (counterparties ) Tj ET Q q 0 0 0 rg BT 368.21 238.00 Td (to ) Tj ET Q q 0 0 0 rg BT 378.74 238.00 Td (mitigate ) Tj ET Q q 0 0 0 rg BT 414.25 238.00 Td (the ) Tj ET Q q 0 0 0 rg BT 429.22 238.00 Td (overall ) Tj ET Q q 0 0 0 rg BT 459.73 238.00 Td (risk ) Tj ET Q q 0 0 0 rg BT 477.48 238.00 Td (of ) Tj ET Q q 0 0 0 rg BT 488.56 238.00 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 541.84 238.00 Td (defaults. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 226.00 Td (For ) Tj ET Q q 0 0 0 rg BT 52.39 226.00 Td (additional ) Tj ET Q q 0 0 0 rg BT 94.88 226.00 Td (information, ) Tj ET Q q 0 0 0 rg BT 147.09 226.00 Td (refer ) Tj ET Q q 0 0 0 rg BT 168.46 226.00 Td (to ) Tj ET Q q 0 0 0 rg BT 178.74 226.00 Td (“Item ) Tj ET Q q 0 0 0 rg BT 204.00 226.00 Td (8. ) Tj ET Q q 0 0 0 rg BT 214.00 226.00 Td (Financial ) Tj ET Q q 0 0 0 rg BT 253.71 226.00 Td (Statements—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 329.54 226.00 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 334.54 226.00 Td (. ) Tj ET Q q 0 0 0 rg BT 339.54 226.00 Td (Financial ) Tj ET Q q 0 0 0 rg BT 379.25 226.00 Td (Instruments ) Tj ET Q q 0 0 0 rg BT 428.96 226.00 Td (and ) Tj ET Q q 0 0 0 rg BT 445.90 226.00 Td (Fair ) Tj ET Q q 0 0 0 rg BT 464.33 226.00 Td (V) Tj ET Q q 0 0 0 rg BT 470.44 226.00 Td (alue ) Tj ET Q q 0 0 0 rg BT 489.60 226.00 Td (Measurements.”) Tj ET Q endstream endobj 115 0 obj <> endobj 116 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (57) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 746.23 Td (Item 8.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 746.23 Td (FINANCIAL) Tj ET Q q 0 0 0 rg BT 151.12 746.23 Td ( ST) Tj ET Q q 0 0 0 rg BT 165.11 746.23 Td (A) Tj ET Q q 0 0 0 rg BT 171.59 746.23 Td (TEMENTS ) Tj ET Q q 0 0 0 rg BT 222.44 746.23 Td (AND SUPPLEMENT) Tj ET Q q 0 0 0 rg BT 314.20 746.23 Td (AR) Tj ET Q q 0 0 0 rg BT 328.29 746.23 Td (Y) Tj ET Q q 0 0 0 rg BT 335.14 746.23 Td ( DA) Tj ET Q q 0 0 0 rg BT 351.34 746.23 Td (T) Tj ET Q q 0 0 0 rg BT 357.27 746.23 Td (A.) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 551.00 742.00 Td ( ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 217.15 721.00 Td (BRIST) Tj ET Q q 0 0 0 rg BT 246.98 721.00 Td (OL-MYERS SQUIBB COMP) Tj ET Q q 0 0 0 rg BT 373.47 721.00 Td (ANY) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 195.45 709.00 Td (CONSOLIDA) Tj ET Q q 0 0 0 rg BT 255.27 709.00 Td (TED ST) Tj ET Q q 0 0 0 rg BT 289.82 709.00 Td (A) Tj ET Q q 0 0 0 rg BT 296.30 709.00 Td (TEMENTS OF) Tj ET Q q 0 0 0 rg BT 361.22 709.00 Td ( EARNINGS) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 215.20 697.00 Td (Dollars in Millions, Except Per) Tj ET Q q 0 0 0 rg BT 346.40 697.00 Td ( Shar) Tj ET Q q 0 0 0 rg BT 369.28 697.00 Td (e Data) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 649.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 649.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 649.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 649.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 649.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 649.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 649.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 623.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 623.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 623.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 623.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 623.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 623.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 623.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 597.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 597.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 597.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 597.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 597.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 597.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 597.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 571.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 571.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 571.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 571.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 571.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 571.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 571.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 545.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 545.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 545.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 545.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 545.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 545.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 545.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 519.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 519.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 519.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 519.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 519.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 519.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 519.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 493.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 493.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 493.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 493.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 493.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 493.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 493.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 467.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 467.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 467.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 467.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 467.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 467.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 467.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 441.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 441.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 441.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 441.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 441.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 441.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 441.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 415.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 415.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 415.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 415.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 415.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 415.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 415.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 389.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 381.50 389.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 385.50 389.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 389.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 389.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 389.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 389.70 61.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 662.7 m 446.5 662.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 662.7 m 450.5 662.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 662.7 m 511.5 662.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 662.7 m 515.5 662.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 662.7 m 576.5 662.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 649.7 m 446.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 649.7 m 511.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 649.7 m 576.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 649.7 m 446.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 649.7 m 511.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 649.7 m 576.5 649.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 623.7 m 446.5 623.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 623.7 m 511.5 623.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 623.7 m 576.5 623.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 545.7 m 446.5 545.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 545.7 m 511.5 545.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 545.7 m 576.5 545.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 532.7 m 446.5 532.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 532.7 m 511.5 532.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 532.7 m 576.5 532.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 493.7 m 446.5 493.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 493.7 m 511.5 493.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 493.7 m 576.5 493.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 480.7 m 446.5 480.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 480.7 m 511.5 480.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 480.7 m 576.5 480.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 467.7 m 446.5 467.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 467.7 m 511.5 467.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 467.7 m 576.5 467.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 455.7 m 446.5 455.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 385.5 453.7 m 446.5 453.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 455.7 m 511.5 455.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 450.5 453.7 m 511.5 453.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 455.7 m 576.5 455.7 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 453.7 m 576.5 453.7 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 666.95 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 436.20 666.93 Td (Y) Tj ET Q q 0 0 0 rg BT 441.53 666.93 Td (ear) Tj ET Q q 0 0 0 rg BT 452.12 666.93 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 512.85 666.93 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 39.00 653.93 Td (EARNINGS) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 407.50 653.93 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 472.50 653.93 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 537.50 653.93 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 640.27 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.00 640.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.15 640.27 Td (19,258) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 640.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 640.27 Td (17,702) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 640.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 640.27 Td (14,045) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 627.27 Td (Alliance and other revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 627.27 Td (1,518) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 627.27 Td (1,725) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 627.27 Td (2,515) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 614.27 Td (T) Tj ET Q q 0 0 0 rg BT 50.41 614.27 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.15 614.27 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 614.27 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 614.27 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 588.27 Td (Cost of products sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 588.27 Td (6,066) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 588.27 Td (4,946) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 588.27 Td (3,909) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 575.27 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 575.27 Td (4,687) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 575.27 Td (4,91) Tj ET Q q 0 0 0 rg BT 502.65 575.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 575.27 Td (4,841) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 562.27 Td (Research and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 562.27 Td (6,41) Tj ET Q q 0 0 0 rg BT 437.65 562.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 562.27 Td (4,940) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 562.27 Td (5,920) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 549.27 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.80 549.32 Td (\(1,519) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 442.65 549.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 549.32 Td (\(1,285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 549.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 549.27 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 549.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 43.50 536.27 Td (T) Tj ET Q q 0 0 0 rg BT 48.91 536.27 Td (otal Expenses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.15 536.27 Td (15,645) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.15 536.27 Td (13,512) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 536.27 Td (14,483) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 510.27 Td (Earnings Before Income ) Tj ET Q q 0 0 0 rg BT 139.15 510.27 Td (T) Tj ET Q q 0 0 0 rg BT 144.82 510.27 Td (axes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 510.27 Td (5,131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 510.27 Td (5,915) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 510.27 Td (2,077) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 497.27 Td (Provision for Income ) Tj ET Q q 0 0 0 rg BT 126.40 497.27 Td (T) Tj ET Q q 0 0 0 rg BT 132.06 497.27 Td (axes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 497.27 Td (4,156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 497.27 Td (1,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 497.27 Td (446) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 484.27 Td (Net Earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.65 484.27 Td (975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 484.27 Td (4,507) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 484.27 Td (1,631) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 471.27 Td (Noncontrolling Interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.30 471.32 Td (\(32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 442.65 471.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 471.27 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 471.27 Td (66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 458.27 Td (Net Earnings ) Tj ET Q q 0 0 0 rg BT 93.71 458.27 Td (Attributable to BMS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.00 458.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 458.27 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 458.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 458.27 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 458.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 458.27 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 432.27 Td (Earnings per Common Share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 419.27 Td (Basic) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.00 419.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.15 419.27 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 419.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.15 419.27 Td (2.67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 419.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 419.27 Td (0.94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 406.27 Td (Diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.00 406.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.15 406.27 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 406.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.15 406.27 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 406.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 406.27 Td (0.93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 380.27 Td (Cash dividends declared per common share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.00 380.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.15 380.27 Td (1.57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 380.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.15 380.27 Td (1.53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 380.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 380.27 Td (1.49) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 154.75 332.20 Td (CONSOLIDA) Tj ET Q q 0 0 0 rg BT 214.57 332.20 Td (TED ST) Tj ET Q q 0 0 0 rg BT 249.13 332.20 Td (A) Tj ET Q q 0 0 0 rg BT 255.60 332.20 Td (TEMENTS OF) Tj ET Q q 0 0 0 rg BT 320.52 332.20 Td ( COMPREHENSIVE INCOME) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 266.25 320.20 Td (Dollars in Millions) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 274.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 274.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 274.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 445.50 274.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 449.50 274.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 274.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 274.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 248.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 248.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 248.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 445.50 248.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 449.50 248.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 248.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 248.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 222.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 222.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 222.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 445.50 222.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 449.50 222.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 222.70 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 222.70 61.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 196.70 345.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 196.70 4.00 -13.00 re f /GS0 gs 0.8 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ET q 0 0 0 rg BT 561.65 148.27 Td (66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 135.27 Td (Comprehensive Income ) Tj ET Q q 0 0 0 rg BT 135.20 135.27 Td (Attributable to BMS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.00 135.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.15 135.27 Td (1,221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.00 135.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.15 135.27 Td (4,422) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 517.00 135.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 135.27 Td (1,522) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 131.30 111.20 Td (The accompanying notes are an integral part of these consolidated financial statements.) 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1 rg /GS0 gs 501.00 199.00 61.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 723 m 497 723 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497 723 m 501 723 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 723 m 562 723 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 713 m 497 713 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 713 m 562 713 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 641 m 497 641 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 629 m 497 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 641 m 562 641 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 629 m 562 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 557 m 497 557 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 546 m 497 546 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 544 m 497 544 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 557 m 562 557 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 546 m 562 546 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 544 m 562 544 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 451 m 497 451 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 439 m 497 439 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 451 m 562 451 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 439 m 562 439 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 391 m 497 391 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 391 m 562 391 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 380 m 497 380 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 380 m 562 380 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 235 m 497 235 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 235 m 562 235 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 211 m 497 211 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 211 m 562 211 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 199 m 497 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 199 m 562 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 188 m 497 188 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 436 186 m 497 186 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 188 m 562 188 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501 186 m 562 186 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 475.25 725.13 Td (December) Tj ET Q q 0 0 0 rg BT 509.82 725.13 Td ( 31,) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 51.50 714.79 Td (ASSETS) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.00 715.13 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 523.00 715.13 Td (2016) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 704.61 Td (Current ) Tj ET Q q 0 0 0 rg BT 79.36 704.61 Td (Assets:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 692.61 Td (Cash and cash equivalents) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 438.50 692.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 692.61 Td (5,421) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 503.50 692.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 692.61 Td (4,237) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 680.61 Td (Marketable securities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 680.61 Td (1,391) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 680.61 Td (2,1) Tj ET Q q 0 0 0 rg BT 550.13 680.61 Td (13) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 668.61 Td (Receivables) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 668.61 Td (6,300) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 668.61 Td (5,543) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 656.61 Td (Inventories) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 656.61 Td (1,166) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 656.61 Td (1,241) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 644.61 Td (Prepaid expenses and other) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 644.61 Td (576) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 644.61 Td (570) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 81.50 632.61 Td (T) Tj ET Q q 0 0 0 rg BT 86.40 632.61 Td (otal Current ) Tj ET Q q 0 0 0 rg BT 128.83 632.61 Td (Assets) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 632.61 Td (14,854) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 632.61 Td (13,704) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 620.61 Td (Property) Tj ET Q q 0 0 0 rg BT 80.50 620.61 Td (, plant and equipment) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 620.61 Td (5,001) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 620.61 Td (4,980) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 608.61 Td (Goodwill) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 608.61 Td (6,863) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 608.61 Td (6,875) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 596.61 Td (Other intangible assets) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 596.61 Td (1,210) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 596.61 Td (1,385) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 584.61 Td (Deferred income taxes) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 584.61 Td (1,610) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 584.61 Td (2,996) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 572.61 Td (Marketable securities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 572.61 Td (2,480) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 572.61 Td (2,719) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 560.61 Td (Other assets) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 560.61 Td (1,533) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 560.61 Td (1,048) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 548.61 Td (T) Tj ET Q q 0 0 0 rg BT 56.40 548.61 Td (otal ) Tj ET Q q 0 0 0 rg BT 70.74 548.61 Td (Assets) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 438.50 548.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 548.61 Td (33,551) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 503.50 548.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 548.61 Td (33,707) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 51.50 525.74 Td (LIABILITIES) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 514.61 Td (Current Liabilities:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 502.61 Td (Short-term debt obligations) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 438.50 502.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 502.61 Td (987) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 503.50 502.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 502.61 Td (992) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 490.61 Td (Accounts payable) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 490.61 Td (2,248) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 490.61 Td (1,664) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 478.61 Td (Accrued liabilities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 478.61 Td (6,014) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 478.61 Td (5,271) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 466.61 Td (Deferred income) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 485.15 466.61 Td (83) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 466.61 Td (762) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 69.50 454.61 Td (Income taxes payable) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 454.61 Td (231) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 454.61 Td (152) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 81.50 442.61 Td (T) Tj ET Q q 0 0 0 rg BT 86.10 442.61 Td (otal Current Liabilities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 442.61 Td (9,563) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 442.61 Td (8,841) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 430.61 Td (Deferred income) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 430.61 Td (454) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 430.61 Td (547) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 418.61 Td (Income taxes payable) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 418.61 Td (3,548) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 418.61 Td (973) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 406.61 Td (Pension and other liabilities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 406.61 Td (1,164) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 406.61 Td (1,283) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 394.61 Td (Long-term debt) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 394.61 Td (6,975) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 394.61 Td (5,716) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 75.50 382.61 Td (T) Tj ET Q q 0 0 0 rg BT 80.40 382.61 Td (otal Liabilities) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 382.61 Td (21,704) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 382.61 Td (17,360) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 361.61 Td (Commitments and contingencies) Tj ET Q BT /F2 8.50 Tf ET q 0 0 0 rg BT 51.50 340.74 Td (EQUITY) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 327.61 Td (Bristol-Myers Squibb Company Shareholders’) Tj ET Q q 0 0 0 rg BT 209.60 327.61 Td ( Equity:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 315.61 Td (Preferred ) Tj ET Q q 0 0 0 rg BT 98.35 315.61 Td (stock, ) Tj ET Q q 0 0 0 rg BT 121.65 315.61 Td ($2 ) Tj ET Q q 0 0 0 rg BT 133.38 315.61 Td (convertible ) Tj ET Q q 0 0 0 rg BT 174.85 315.61 Td (series, ) Tj ET Q q 0 0 0 rg BT 199.56 315.61 Td (par ) Tj ET Q q 0 0 0 rg BT 213.64 315.61 Td (value ) Tj ET Q q 0 0 0 rg BT 235.28 315.61 Td ($1 ) Tj ET Q q 0 0 0 rg BT 247.01 315.61 Td (per ) Tj ET Q q 0 0 0 rg BT 261.10 315.61 Td (share: ) Tj ET Q q 0 0 0 rg BT 284.15 315.61 Td (Authorized ) Tj ET Q q 0 0 0 rg BT 325.38 315.61 Td (10 ) Tj ET Q q 0 0 0 rg BT 337.12 315.61 Td (million ) Tj ET Q q 0 0 0 rg BT 364.91 315.61 Td (shares; ) Tj ET Q q 0 0 0 rg BT 391.74 315.61 Td (issued ) Tj ET Q q 0 0 0 rg BT 416.22 315.61 Td (and ) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 307.11 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 105.29 307.11 Td (4,070 ) Tj ET Q q 0 0 0 rg BT 126.54 307.11 Td (in ) Tj ET Q q 0 0 0 rg BT 135.28 307.11 Td (2017 ) Tj ET Q q 0 0 0 rg BT 154.40 307.11 Td (and ) Tj ET Q q 0 0 0 rg BT 168.80 307.11 Td (4,129 ) Tj ET Q q 0 0 0 rg BT 190.05 307.11 Td (in ) Tj ET Q q 0 0 0 rg BT 198.79 307.11 Td (2016, ) Tj ET Q q 0 0 0 rg BT 220.04 307.11 Td (liquidation ) Tj ET Q q 0 0 0 rg BT 259.00 307.11 Td (value ) Tj ET Q q 0 0 0 rg BT 279.53 307.11 Td (of ) Tj ET Q q 0 0 0 rg BT 288.73 307.11 Td ($50 ) Tj ET Q q 0 0 0 rg BT 303.61 307.11 Td (per ) Tj ET Q q 0 0 0 rg BT 316.59 307.11 Td (share) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 485.15 307.36 Td (—) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 550.15 307.36 Td (—) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 294.61 Td (Common ) Tj ET Q q 0 0 0 rg BT 97.48 294.61 Td (stock, ) Tj ET Q q 0 0 0 rg BT 119.88 294.61 Td (par ) Tj ET Q q 0 0 0 rg BT 133.08 294.61 Td (value ) Tj ET Q q 0 0 0 rg BT 153.82 294.61 Td (of ) Tj ET Q q 0 0 0 rg BT 163.24 294.61 Td ($0.10 ) Tj ET Q q 0 0 0 rg BT 184.70 294.61 Td (per ) Tj ET Q q 0 0 0 rg BT 197.89 294.61 Td (share: ) Tj ET Q q 0 0 0 rg BT 220.01 294.61 Td (Authorized ) Tj ET Q q 0 0 0 rg BT 260.58 294.61 Td (4.5 ) Tj ET Q q 0 0 0 rg BT 273.54 294.61 Td (billion ) Tj ET Q q 0 0 0 rg BT 298.08 294.61 Td (shares; ) Tj ET Q q 0 0 0 rg BT 324.02 294.61 Td (2.2 ) Tj ET Q q 0 0 0 rg BT 336.98 294.61 Td (billion ) Tj ET Q q 0 0 0 rg BT 361.52 294.61 Td (issued ) Tj ET Q q 0 0 0 rg BT 385.10 294.61 Td (in ) Tj ET Q q 0 0 0 rg BT 394.05 294.61 Td (both ) Tj ET Q q 0 0 0 rg BT 411.50 294.61 Td (2017 ) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 286.11 Td (and ) Tj ET Q q 0 0 0 rg BT 77.90 286.11 Td (2016) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 287.36 Td (221) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 287.36 Td (221) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 274.61 Td (Capital in excess of par value of stock) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 474.50 274.61 Td (1,898) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 539.50 274.61 Td (1,725) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 262.61 Td (Accumulated other comprehensive loss) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 471.65 262.61 Td (\(2,289) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 493.65 262.61 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 536.65 262.61 Td (\(2,503) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 558.65 262.61 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 250.61 Td (Retained earnings) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 250.61 Td (31,160) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 250.61 Td (33,513) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 63.50 238.61 Td (Less cost of treasury stock — 575 million common shares in 2017 and 536 million in 2016) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 467.40 238.61 Td (\(19,249) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 493.65 238.61 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 532.40 238.61 Td (\(16,779) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 558.65 238.61 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 75.50 226.61 Td (T) Tj ET Q q 0 0 0 rg BT 80.10 226.61 Td (otal Bristol-Myers Squibb Company Shareholders' Equity) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 226.61 Td (1) Tj ET Q q 0 0 0 rg BT 474.50 226.61 Td (1,741) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 226.61 Td (16,177) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 214.61 Td (Noncontrolling interest) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 480.90 214.61 Td (106) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 545.90 214.61 Td (170) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 87.50 202.61 Td (T) Tj ET Q q 0 0 0 rg BT 92.10 202.61 Td (otal Equity) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 202.61 Td (1) Tj ET Q q 0 0 0 rg BT 474.50 202.61 Td (1,847) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 202.61 Td (16,347) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 51.50 190.61 Td (T) Tj ET Q q 0 0 0 rg BT 56.10 190.61 Td (otal Liabilities and Equity) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 438.50 190.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 470.25 190.61 Td (33,551) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 503.50 190.61 Td ($) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 535.25 190.61 Td (33,707) Tj ET Q BT /F1 10.00 Tf ET BT /F1 9.00 Tf ET q 0 0 0 rg BT 148.80 165.95 Td (The accompanying notes are an integral part of these consolidated financial statements.) 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10.00 Tf ET q 0 0 0 rg BT 559.15 294.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 70.50 281.57 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.80 281.62 Td (\(22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.15 281.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.15 281.57 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.80 281.62 Td (\(9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.15 281.57 Td (\)) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 88.50 268.73 Td (Net Cash Used in Financing ) Tj ET Q q 0 0 0 rg BT 209.35 268.73 Td (Activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.30 268.62 Td (\(4,077) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.15 268.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 268.62 Td (\(2,653) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 268.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.30 268.62 Td (\(3,624) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.15 268.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 52.50 255.57 Td (Ef) Tj ET Q q 0 0 0 rg BT 61.85 255.57 Td (fect of Exchange Rates on Cash and Cash Equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.15 255.57 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.80 255.62 Td (\(33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 255.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.80 255.62 Td (\(95) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.15 255.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 52.50 242.57 Td (Increase/\(Decrease\) in Cash and Cash Equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 242.57 Td (1,184) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 242.57 Td (1,852) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.30 242.62 Td (\(3,186) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.15 242.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 52.50 229.57 Td (Cash and Cash Equivalents at Beginning of ) Tj ET Q q 0 0 0 rg BT 228.49 229.57 Td (Y) Tj ET Q q 0 0 0 rg BT 234.71 229.57 Td (ear) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 229.57 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 229.57 Td (2,385) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 536.65 229.57 Td (5,571) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 52.50 216.73 Td (Cash and Cash Equivalents at End of ) Tj ET Q q 0 0 0 rg BT 214.13 216.73 Td (Y) Tj ET Q q 0 0 0 rg BT 220.24 216.73 Td (ear) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.50 216.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 216.57 Td (5,421) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.50 216.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 216.57 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.50 216.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 536.65 216.57 Td (2,385) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 131.30 192.50 Td (The accompanying notes are an integral part of these consolidated financial statements.) Tj ET Q endstream endobj 121 0 obj <> endobj 122 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (60) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 737.10 Td (1) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 737.10 Td (. ) Tj ET Q q 0 0 0 rg BT 67.94 737.10 Td (ACCOUNTING ) Tj ET Q q 0 0 0 rg BT 139.89 737.10 Td (POLICIES ) Tj ET Q q 0 0 0 rg BT 189.63 737.10 Td (AND ) Tj ET Q q 0 0 0 rg BT 213.79 737.10 Td (RECENTL) Tj ET Q q 0 0 0 rg BT 261.22 737.10 Td (Y) Tj ET Q q 0 0 0 rg BT 268.07 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 270.57 737.10 Td (ISSUED ) Tj ET Q q 0 0 0 rg BT 308.65 737.10 Td (ACCOUNTING ) Tj ET Q q 0 0 0 rg BT 380.59 737.10 Td (ST) Tj ET Q q 0 0 0 rg BT 392.08 737.10 Td (ANDARDS) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (Basis ) Tj ET Q q 0 0 0 rg BT 60.73 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 71.56 713.10 Td (Consolidation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 693.10 Td (The ) Tj ET Q q 0 0 0 rg BT 55.01 693.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 109.01 693.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 147.46 693.10 Td (statements ) Tj ET Q q 0 0 0 rg BT 193.13 693.10 Td (are ) Tj ET Q q 0 0 0 rg BT 208.80 693.10 Td (prepared ) Tj ET Q q 0 0 0 rg BT 247.24 693.10 Td (in ) Tj ET Q q 0 0 0 rg BT 258.48 693.10 Td (conformity ) Tj ET Q q 0 0 0 rg BT 306.37 693.10 Td (with ) Tj ET Q q 0 0 0 rg BT 327.61 693.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 348.86 693.10 Td (GAAP) Tj ET Q q 0 0 0 rg BT 374.97 693.10 Td (, ) Tj ET Q q 0 0 0 rg BT 380.94 693.10 Td (including ) Tj ET Q q 0 0 0 rg BT 422.17 693.10 Td (the ) Tj ET Q q 0 0 0 rg BT 437.85 693.10 Td (accounts ) Tj ET Q q 0 0 0 rg BT 476.30 693.10 Td (of ) Tj ET Q q 0 0 0 rg BT 488.09 693.10 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 547.66 693.10 Td (Squibb ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 681.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 78.44 681.10 Td (and ) Tj ET Q q 0 0 0 rg BT 96.42 681.10 Td (all ) Tj ET Q q 0 0 0 rg BT 109.97 681.10 Td (of ) Tj ET Q q 0 0 0 rg BT 121.85 681.10 Td (its ) Tj ET Q q 0 0 0 rg BT 134.84 681.10 Td (controlled ) Tj ET Q q 0 0 0 rg BT 178.93 681.10 Td (majority-owned ) Tj ET Q q 0 0 0 rg BT 246.35 681.10 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 297.12 681.10 Td (and ) Tj ET Q q 0 0 0 rg BT 315.11 681.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 345.86 681.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 381.61 681.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 414.59 681.10 Td (entities. ) Tj ET Q q 0 0 0 rg BT 448.74 681.10 Td (All ) Tj ET Q q 0 0 0 rg BT 465.07 681.10 Td (intercompany ) Tj ET Q q 0 0 0 rg BT 523.60 681.10 Td (balances ) Tj ET Q q 0 0 0 rg BT 561.57 681.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 669.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 85.32 669.10 Td (are ) Tj ET Q q 0 0 0 rg BT 99.08 669.10 Td (eliminated. ) Tj ET Q q 0 0 0 rg BT 145.34 669.10 Td (Material ) Tj ET Q q 0 0 0 rg BT 180.77 669.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 226.76 669.10 Td (events ) Tj ET Q q 0 0 0 rg BT 253.86 669.10 Td (are ) Tj ET Q q 0 0 0 rg BT 267.62 669.10 Td (evaluated ) Tj ET Q q 0 0 0 rg BT 307.49 669.10 Td (and ) Tj ET Q q 0 0 0 rg BT 323.48 669.10 Td (disclosed ) Tj ET Q q 0 0 0 rg BT 362.25 669.10 Td (through ) Tj ET Q q 0 0 0 rg BT 394.91 669.10 Td (the ) Tj ET Q q 0 0 0 rg BT 408.68 669.10 Td (report ) Tj ET Q q 0 0 0 rg BT 434.11 669.10 Td (issuance ) Tj ET Q q 0 0 0 rg BT 469.55 669.10 Td (date. ) Tj ET Q q 0 0 0 rg BT 490.26 669.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 514.02 669.10 Td (to ) Tj ET Q q 0 0 0 rg BT 523.35 669.10 Td (the ) Tj ET Q q 0 0 0 rg BT 537.12 669.10 Td (Summary ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 657.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.28 657.10 Td (Abbreviated ) Tj ET Q q 0 0 0 rg BT 98.02 657.10 Td (T) Tj ET Q q 0 0 0 rg BT 103.43 657.10 Td (erms ) Tj ET Q q 0 0 0 rg BT 125.37 657.10 Td (at ) Tj ET Q q 0 0 0 rg BT 135.09 657.10 Td (the ) Tj ET Q q 0 0 0 rg BT 149.80 657.10 Td (end ) Tj ET Q q 0 0 0 rg BT 166.74 657.10 Td (of ) Tj ET Q q 0 0 0 rg BT 177.57 657.10 Td (this ) Tj ET Q q 0 0 0 rg BT 194.52 657.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 217.02 657.10 Td (Form ) Tj ET Q q 0 0 0 rg BT 241.19 657.10 Td (10-K ) Tj ET Q q 0 0 0 rg BT 264.24 657.10 Td (for ) Tj ET Q q 0 0 0 rg BT 278.40 657.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 303.12 657.10 Td (used ) Tj ET Q q 0 0 0 rg BT 323.95 657.10 Td (throughout ) Tj ET Q q 0 0 0 rg BT 370.34 657.10 Td (the ) Tj ET Q q 0 0 0 rg BT 385.05 657.10 Td (document.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 633.10 Td (Alliance ) Tj ET Q q 0 0 0 rg BT 71.64 633.10 Td (and ) Tj ET Q q 0 0 0 rg BT 87.84 633.10 Td (license ) Tj ET Q q 0 0 0 rg BT 117.37 633.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 173.00 633.10 Td (are ) Tj ET Q q 0 0 0 rg BT 186.97 633.10 Td (assessed ) Tj ET Q q 0 0 0 rg BT 222.62 633.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.16 633.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 273.91 633.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 307.88 633.10 Td (the ) Tj ET Q q 0 0 0 rg BT 321.86 633.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 345.84 633.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 378.15 633.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 418.79 633.10 Td (or ) Tj ET Q q 0 0 0 rg BT 428.89 633.10 Td (other ) Tj ET Q q 0 0 0 rg BT 451.20 633.10 Td (control ) Tj ET Q q 0 0 0 rg BT 481.29 633.10 Td (over ) Tj ET Q q 0 0 0 rg BT 500.82 633.10 Td (the ) Tj ET Q q 0 0 0 rg BT 514.80 633.10 Td (entity ) Tj ET Q q 0 0 0 rg BT 539.34 633.10 Td (requiring ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.10 Td (consolidation ) Tj ET Q q 0 0 0 rg BT 92.66 621.10 Td (of ) Tj ET Q q 0 0 0 rg BT 103.77 621.10 Td (an ) Tj ET Q q 0 0 0 rg BT 115.98 621.10 Td (entity) Tj ET Q q 0 0 0 rg BT 138.11 621.10 Td (. ) Tj ET Q q 0 0 0 rg BT 143.38 621.10 Td (Entities ) Tj ET Q q 0 0 0 rg BT 176.71 621.10 Td (controlled ) Tj ET Q q 0 0 0 rg BT 220.03 621.10 Td (by ) Tj ET Q q 0 0 0 rg BT 232.81 621.10 Td (means ) Tj ET Q q 0 0 0 rg BT 261.13 621.10 Td (other ) Tj ET Q q 0 0 0 rg BT 284.46 621.10 Td (than ) Tj ET Q q 0 0 0 rg BT 304.45 621.10 Td (a ) Tj ET Q q 0 0 0 rg BT 311.67 621.10 Td (majority ) Tj ET Q q 0 0 0 rg BT 348.33 621.10 Td (voting ) Tj ET Q q 0 0 0 rg BT 376.66 621.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 408.87 621.10 Td (are ) Tj ET Q q 0 0 0 rg BT 423.86 621.10 Td (referred ) Tj ET Q q 0 0 0 rg BT 458.27 621.10 Td (to ) Tj ET Q q 0 0 0 rg BT 468.83 621.10 Td (as ) Tj ET Q q 0 0 0 rg BT 479.93 621.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 514.91 621.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 547.12 621.10 Td (entities ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 609.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.93 609.10 Td (are ) Tj ET Q q 0 0 0 rg BT 67.63 609.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 120.67 609.10 Td (when ) Tj ET Q q 0 0 0 rg BT 144.82 609.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 168.44 609.10 Td (has ) Tj ET Q q 0 0 0 rg BT 184.27 609.10 Td (both ) Tj ET Q q 0 0 0 rg BT 204.54 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 219.25 609.10 Td (power ) Tj ET Q q 0 0 0 rg BT 246.73 609.10 Td (to ) Tj ET Q q 0 0 0 rg BT 257.01 609.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 282.26 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 296.97 609.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 335.57 609.10 Td (of ) Tj ET Q q 0 0 0 rg BT 346.39 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 361.10 609.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 395.80 609.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 427.73 609.10 Td (entity ) Tj ET Q q 0 0 0 rg BT 452.99 609.10 Td (that ) Tj ET Q q 0 0 0 rg BT 470.48 609.10 Td (most ) Tj ET Q q 0 0 0 rg BT 492.43 609.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 544.91 609.10 Td (impacts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 597.10 Td (its ) Tj ET Q q 0 0 0 rg BT 48.13 597.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 89.68 597.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 142.88 597.10 Td (and ) Tj ET Q q 0 0 0 rg BT 160.00 597.10 Td (the ) Tj ET Q q 0 0 0 rg BT 174.90 597.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 218.13 597.10 Td (to ) Tj ET Q q 0 0 0 rg BT 228.59 597.10 Td (absorb ) Tj ET Q q 0 0 0 rg BT 257.93 597.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 284.50 597.10 Td (or ) Tj ET Q q 0 0 0 rg BT 295.51 597.10 Td (the ) Tj ET Q q 0 0 0 rg BT 310.40 597.10 Td (right ) Tj ET Q q 0 0 0 rg BT 331.97 597.10 Td (to ) Tj ET Q q 0 0 0 rg BT 342.43 597.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 373.97 597.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 408.30 597.10 Td (that ) Tj ET Q q 0 0 0 rg BT 425.98 597.10 Td (could ) Tj ET Q q 0 0 0 rg BT 450.88 597.10 Td (potentially ) Tj ET Q q 0 0 0 rg BT 496.32 597.10 Td (be ) Tj ET Q q 0 0 0 rg BT 508.44 597.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 553.33 597.10 Td (to ) Tj ET Q q 0 0 0 rg BT 563.79 597.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 585.10 Td (entity) Tj ET Q q 0 0 0 rg BT 58.12 585.10 Td (.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 561.10 Td (Use of Estimates and Judgments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 541.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.76 541.10 Td (preparation ) Tj ET Q q 0 0 0 rg BT 103.51 541.10 Td (of ) Tj ET Q q 0 0 0 rg BT 115.06 541.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 153.26 541.10 Td (statements ) Tj ET Q q 0 0 0 rg BT 198.69 541.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 234.12 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 249.55 541.10 Td (use ) Tj ET Q q 0 0 0 rg BT 266.10 541.10 Td (of ) Tj ET Q q 0 0 0 rg BT 277.65 541.10 Td (management ) Tj ET Q q 0 0 0 rg BT 331.95 541.10 Td (estimates, ) Tj ET Q q 0 0 0 rg BT 374.88 541.10 Td (judgments ) Tj ET Q q 0 0 0 rg BT 419.76 541.10 Td (and ) Tj ET Q q 0 0 0 rg BT 437.42 541.10 Td (assumptions. ) Tj ET Q q 0 0 0 rg BT 492.35 541.10 Td (The ) Tj ET Q q 0 0 0 rg BT 511.12 541.10 Td (most ) Tj ET Q q 0 0 0 rg BT 533.79 541.10 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 529.10 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 88.20 529.10 Td (are ) Tj ET Q q 0 0 0 rg BT 103.17 529.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 143.14 529.10 Td (in ) Tj ET Q q 0 0 0 rg BT 153.67 529.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 204.75 529.10 Td (the ) Tj ET Q q 0 0 0 rg BT 219.72 529.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 236.35 529.10 Td (value ) Tj ET Q q 0 0 0 rg BT 260.77 529.10 Td (and ) Tj ET Q q 0 0 0 rg BT 277.96 529.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 315.71 529.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 364.56 529.10 Td (of ) Tj ET Q q 0 0 0 rg BT 375.65 529.10 Td (intangible ) Tj ET Q q 0 0 0 rg BT 418.40 529.10 Td (assets; ) Tj ET Q q 0 0 0 rg BT 447.26 529.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 469.45 529.10 Td (rebate ) Tj ET Q q 0 0 0 rg BT 496.63 529.10 Td (and ) Tj ET Q q 0 0 0 rg BT 513.83 529.10 Td (return ) Tj ET Q q 0 0 0 rg BT 540.46 529.10 Td (accruals; ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 517.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 58.01 517.10 Td (contingencies; ) Tj ET Q q 0 0 0 rg BT 118.35 517.10 Td (income ) Tj ET Q q 0 0 0 rg BT 150.37 517.10 Td (taxes; ) Tj ET Q q 0 0 0 rg BT 176.27 517.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 227.17 517.10 Td (if ) Tj ET Q q 0 0 0 rg BT 235.86 517.10 Td (an ) Tj ET Q q 0 0 0 rg BT 247.88 517.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 294.34 517.10 Td (or ) Tj ET Q q 0 0 0 rg BT 305.26 517.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 350.05 517.10 Td (is ) Tj ET Q q 0 0 0 rg BT 359.30 517.10 Td (a ) Tj ET Q q 0 0 0 rg BT 366.32 517.10 Td (business ) Tj ET Q q 0 0 0 rg BT 402.79 517.10 Td (or ) Tj ET Q q 0 0 0 rg BT 413.70 517.10 Td (an ) Tj ET Q q 0 0 0 rg BT 425.72 517.10 Td (asset; ) Tj ET Q q 0 0 0 rg BT 450.52 517.10 Td (and ) Tj ET Q q 0 0 0 rg BT 467.54 517.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 501.22 517.10 Td (and ) Tj ET Q q 0 0 0 rg BT 518.24 517.10 Td (postretirement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 505.10 Td (benefits. ) Tj ET Q q 0 0 0 rg BT 72.10 505.10 Td (Actual ) Tj ET Q q 0 0 0 rg BT 101.26 505.10 Td (results ) Tj ET Q q 0 0 0 rg BT 129.87 505.10 Td (may ) Tj ET Q q 0 0 0 rg BT 149.58 505.10 Td (dif) Tj ET Q q 0 0 0 rg BT 160.51 505.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 174.11 505.10 Td (from ) Tj ET Q q 0 0 0 rg BT 196.05 505.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 236.87 505.10 Td (results.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 481.10 Td (Reclassifications) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (Certain ) Tj ET Q q 0 0 0 rg BT 68.06 461.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 90.13 461.10 Td (period ) Tj ET Q q 0 0 0 rg BT 118.30 461.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 154.82 461.10 Td (were ) Tj ET Q q 0 0 0 rg BT 176.88 461.10 Td (reclassified ) Tj ET Q q 0 0 0 rg BT 225.04 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 235.44 461.10 Td (conform ) Tj ET Q q 0 0 0 rg BT 271.95 461.10 Td (to ) Tj ET Q q 0 0 0 rg BT 282.36 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 297.20 461.10 Td (current ) Tj ET Q q 0 0 0 rg BT 328.15 461.10 Td (period ) Tj ET Q q 0 0 0 rg BT 356.32 461.10 Td (presentation. ) Tj ET Q q 0 0 0 rg BT 410.13 461.10 Td (The ) Tj ET Q q 0 0 0 rg BT 428.31 461.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 481.48 461.10 Td (statement ) Tj ET Q q 0 0 0 rg BT 522.43 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.38 461.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 553.78 461.10 Td (flows ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 80.16 449.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 120.41 449.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 151.78 449.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 168.71 449.10 Td (swap ) Tj ET Q q 0 0 0 rg BT 191.20 449.10 Td (contract ) Tj ET Q q 0 0 0 rg BT 225.34 449.10 Td (terminations ) Tj ET Q q 0 0 0 rg BT 277.26 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 293.64 449.10 Td (issuance ) Tj ET Q q 0 0 0 rg BT 329.46 449.10 Td (of ) Tj ET Q q 0 0 0 rg BT 339.73 449.10 Td (common ) Tj ET Q q 0 0 0 rg BT 376.66 449.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 399.71 449.10 Td (as ) Tj ET Q q 0 0 0 rg BT 409.97 449.10 Td (separate ) Tj ET Q q 0 0 0 rg BT 444.67 449.10 Td (line ) Tj ET Q q 0 0 0 rg BT 461.60 449.10 Td (items ) Tj ET Q q 0 0 0 rg BT 485.20 449.10 Td (within ) Tj ET Q q 0 0 0 rg BT 512.70 449.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 532.41 449.10 Td (flows ) Tj ET Q q 0 0 0 rg BT 556.57 449.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 76.52 437.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 115.37 437.10 Td (which ) Tj ET Q q 0 0 0 rg BT 142.56 437.10 Td (are ) Tj ET Q q 0 0 0 rg BT 157.51 437.10 Td (now ) Tj ET Q q 0 0 0 rg BT 177.49 437.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 218.55 437.10 Td (as ) Tj ET Q q 0 0 0 rg BT 229.64 437.10 Td (components ) Tj ET Q q 0 0 0 rg BT 280.71 437.10 Td (of ) Tj ET Q q 0 0 0 rg BT 291.79 437.10 Td (other ) Tj ET Q q 0 0 0 rg BT 315.09 437.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 355.61 437.10 Td (activities. ) Tj ET Q q 0 0 0 rg BT 396.76 437.10 Td (The ) Tj ET Q q 0 0 0 rg BT 415.06 437.10 Td (reclassifications ) Tj ET Q q 0 0 0 rg BT 482.23 437.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 515.53 437.10 Td (a ) Tj ET Q q 0 0 0 rg BT 522.72 437.10 Td (more ) Tj ET Q q 0 0 0 rg BT 546.01 437.10 Td (concise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 73.48 425.10 Td (statements ) Tj ET Q q 0 0 0 rg BT 118.19 425.10 Td (presentations ) Tj ET Q q 0 0 0 rg BT 173.46 425.10 Td (and ) Tj ET Q q 0 0 0 rg BT 190.39 425.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 232.88 425.10 Td (information ) Tj ET Q q 0 0 0 rg BT 282.60 425.10 Td (is ) Tj ET Q q 0 0 0 rg BT 291.77 425.10 Td (disclosed ) Tj ET Q q 0 0 0 rg BT 331.48 425.10 Td (in ) Tj ET Q q 0 0 0 rg BT 341.76 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 356.48 425.10 Td (notes ) Tj ET Q q 0 0 0 rg BT 380.09 425.10 Td (if ) Tj ET Q q 0 0 0 rg BT 388.70 425.10 Td (material.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (Revenue Recognition) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 381.10 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 74.39 381.10 Td (is ) Tj ET Q q 0 0 0 rg BT 84.47 381.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 131.73 381.10 Td (when ) Tj ET Q q 0 0 0 rg BT 156.80 381.10 Td (persuasive ) Tj ET Q q 0 0 0 rg BT 202.41 381.10 Td (evidence ) Tj ET Q q 0 0 0 rg BT 241.35 381.10 Td (of ) Tj ET Q q 0 0 0 rg BT 253.09 381.10 Td (an ) Tj ET Q q 0 0 0 rg BT 265.93 381.10 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 319.31 381.10 Td (exists, ) Tj ET Q q 0 0 0 rg BT 347.99 381.10 Td (the ) Tj ET Q q 0 0 0 rg BT 363.61 381.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 386.46 381.10 Td (price ) Tj ET Q q 0 0 0 rg BT 409.85 381.10 Td (is ) Tj ET Q q 0 0 0 rg BT 419.93 381.10 Td (fixed ) Tj ET Q q 0 0 0 rg BT 443.88 381.10 Td (or ) Tj ET Q q 0 0 0 rg BT 455.61 381.10 Td (determinable, ) Tj ET Q q 0 0 0 rg BT 513.72 381.10 Td (collectability ) Tj ET Q q 0 0 0 rg BT 569.33 381.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 81.44 369.10 Td (assured ) Tj ET Q q 0 0 0 rg BT 113.56 369.10 Td (and ) Tj ET Q q 0 0 0 rg BT 130.13 369.10 Td (title ) Tj ET Q q 0 0 0 rg BT 147.81 369.10 Td (and ) Tj ET Q q 0 0 0 rg BT 164.38 369.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 217.06 369.10 Td (all ) Tj ET Q q 0 0 0 rg BT 229.18 369.10 Td (risks ) Tj ET Q q 0 0 0 rg BT 250.20 369.10 Td (and ) Tj ET Q q 0 0 0 rg BT 266.77 369.10 Td (rewards ) Tj ET Q q 0 0 0 rg BT 300.55 369.10 Td (of ) Tj ET Q q 0 0 0 rg BT 311.01 369.10 Td (ownership ) Tj ET Q q 0 0 0 rg BT 354.80 369.10 Td (are ) Tj ET Q q 0 0 0 rg BT 369.13 369.10 Td (transferred, ) Tj ET Q q 0 0 0 rg BT 417.07 369.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 456.40 369.10 Td (at ) Tj ET Q q 0 0 0 rg BT 465.75 369.10 Td (time ) Tj ET Q q 0 0 0 rg BT 485.65 369.10 Td (of ) Tj ET Q q 0 0 0 rg BT 496.11 369.10 Td (shipment ) Tj ET Q q 0 0 0 rg BT 534.90 369.10 Td (\(including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.78 357.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 80.00 357.10 Td (of ) Tj ET Q q 0 0 0 rg BT 90.89 357.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 140.65 357.10 Td (products ) Tj ET Q q 0 0 0 rg BT 177.65 357.10 Td (to ) Tj ET Q q 0 0 0 rg BT 187.98 357.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 221.63 357.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 256.40 357.10 Td (when ) Tj ET Q q 0 0 0 rg BT 280.61 357.10 Td (they ) Tj ET Q q 0 0 0 rg BT 300.39 357.10 Td (are ) Tj ET Q q 0 0 0 rg BT 315.16 357.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.93 357.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 368.03 357.10 Td (in ) Tj ET Q q 0 0 0 rg BT 378.37 357.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.14 357.10 Td (end ) Tj ET Q q 0 0 0 rg BT 410.14 357.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 449.35 357.10 Td (sale\). ) Tj ET Q q 0 0 0 rg BT 473.29 357.10 Td (However) Tj ET Q q 0 0 0 rg BT 509.54 357.10 Td (, ) Tj ET Q q 0 0 0 rg BT 514.60 357.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 544.36 357.10 Td (revenue ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.86 345.10 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 85.51 345.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 130.27 345.10 Td (is ) Tj ET Q q 0 0 0 rg BT 139.47 345.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 185.87 345.10 Td (on ) Tj ET Q q 0 0 0 rg BT 198.40 345.10 Td (the ) Tj ET Q q 0 0 0 rg BT 213.15 345.10 Td (date ) Tj ET Q q 0 0 0 rg BT 232.34 345.10 Td (of ) Tj ET Q q 0 0 0 rg BT 243.21 345.10 Td (receipt ) Tj ET Q q 0 0 0 rg BT 272.94 345.10 Td (by ) Tj ET Q q 0 0 0 rg BT 285.48 345.10 Td (the ) Tj ET Q q 0 0 0 rg BT 300.23 345.10 Td (customer) Tj ET Q q 0 0 0 rg BT 336.33 345.10 Td (. ) Tj ET Q q 0 0 0 rg BT 340.81 345.10 Td (Alliance ) Tj ET Q q 0 0 0 rg BT 377.21 345.10 Td (and ) Tj ET Q q 0 0 0 rg BT 394.19 345.10 Td (other ) Tj ET Q q 0 0 0 rg BT 417.27 345.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 451.45 345.10 Td (related ) Tj ET Q q 0 0 0 rg BT 481.18 345.10 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 491.50 345.10 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.16 345.10 Td ( ) Tj ET Q q 0 0 0 rg BT 525.69 345.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 542.66 345.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 576.00 345.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.10 Td (is ) Tj ET Q q 0 0 0 rg BT 45.42 333.10 Td (not ) Tj ET Q q 0 0 0 rg BT 60.94 333.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 107.55 333.10 Td (until ) Tj ET Q q 0 0 0 rg BT 128.63 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 143.60 333.10 Td (products ) Tj ET Q q 0 0 0 rg BT 180.78 333.10 Td (are ) Tj ET Q q 0 0 0 rg BT 195.73 333.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 215.15 333.10 Td (to ) Tj ET Q q 0 0 0 rg BT 225.68 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 240.64 333.10 Td (end ) Tj ET Q q 0 0 0 rg BT 257.82 333.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 297.23 333.10 Td (by ) Tj ET Q q 0 0 0 rg BT 309.97 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 324.94 333.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 358.77 333.10 Td (partner) Tj ET Q q 0 0 0 rg BT 386.53 333.10 Td (. ) Tj ET Q q 0 0 0 rg BT 391.78 333.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 432.30 333.10 Td (are ) Tj ET Q q 0 0 0 rg BT 447.25 333.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 493.86 333.10 Td (when ) Tj ET Q q 0 0 0 rg BT 518.27 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 533.23 333.10 Td (third-party ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 321.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 57.28 321.10 Td (are ) Tj ET Q q 0 0 0 rg BT 71.33 321.10 Td (reliably ) Tj ET Q q 0 0 0 rg BT 103.71 321.10 Td (measurable ) Tj ET Q q 0 0 0 rg BT 151.08 321.10 Td (and ) Tj ET Q q 0 0 0 rg BT 167.36 321.10 Td (collectability ) Tj ET Q q 0 0 0 rg BT 221.41 321.10 Td (is ) Tj ET Q q 0 0 0 rg BT 229.92 321.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 275.07 321.10 Td (assured. ) Tj ET Q q 0 0 0 rg BT 309.40 321.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 333.45 321.10 Td (to ) Tj ET Q q 0 0 0 rg BT 343.07 321.10 Td (“—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.79 321.10 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.79 321.10 Td (. ) Tj ET Q q 0 0 0 rg BT 387.72 321.10 Td (Alliances” ) Tj ET Q q 0 0 0 rg BT 431.77 321.10 Td (for ) Tj ET Q q 0 0 0 rg BT 445.27 321.10 Td (further ) Tj ET Q q 0 0 0 rg BT 474.31 321.10 Td (detail ) Tj ET Q q 0 0 0 rg BT 498.37 321.10 Td (regarding ) Tj ET Q q 0 0 0 rg BT 538.52 321.10 Td (alliances.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.10 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 74.24 297.10 Td (is ) Tj ET Q q 0 0 0 rg BT 84.17 297.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 119.07 297.10 Td (at ) Tj ET Q q 0 0 0 rg BT 129.54 297.10 Td (the ) Tj ET Q q 0 0 0 rg BT 145.01 297.10 Td (time ) Tj ET Q q 0 0 0 rg BT 166.04 297.10 Td (of ) Tj ET Q q 0 0 0 rg BT 177.63 297.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 226.43 297.10 Td (for ) Tj ET Q q 0 0 0 rg BT 241.34 297.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 280.13 297.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 302.83 297.10 Td (returns, ) Tj ET Q q 0 0 0 rg BT 336.35 297.10 Td (discounts, ) Tj ET Q q 0 0 0 rg BT 379.88 297.10 Td (rebates ) Tj ET Q q 0 0 0 rg BT 411.46 297.10 Td (and ) Tj ET Q q 0 0 0 rg BT 429.15 297.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 451.84 297.10 Td (allowances ) Tj ET Q q 0 0 0 rg BT 499.52 297.10 Td (based ) Tj ET Q q 0 0 0 rg BT 525.55 297.10 Td (on ) Tj ET Q q 0 0 0 rg BT 538.80 297.10 Td (historical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 81.46 285.10 Td (updated ) Tj ET Q q 0 0 0 rg BT 115.27 285.10 Td (for ) Tj ET Q q 0 0 0 rg BT 129.08 285.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 163.44 285.10 Td (in ) Tj ET Q q 0 0 0 rg BT 173.38 285.10 Td (facts ) Tj ET Q q 0 0 0 rg BT 194.41 285.10 Td (and ) Tj ET Q q 0 0 0 rg BT 211.00 285.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 269.80 285.10 Td (including ) Tj ET Q q 0 0 0 rg BT 309.72 285.10 Td (the ) Tj ET Q q 0 0 0 rg BT 324.10 285.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 353.46 285.10 Td (of ) Tj ET Q q 0 0 0 rg BT 363.95 285.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 407.19 285.10 Td (healthcare ) Tj ET Q q 0 0 0 rg BT 450.42 285.10 Td (legislation. ) Tj ET Q q 0 0 0 rg BT 496.74 285.10 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 533.88 285.10 Td (is ) Tj ET Q q 0 0 0 rg BT 542.70 285.10 Td (deferred ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.10 Td (when ) Tj ET Q q 0 0 0 rg BT 60.02 273.10 Td (there ) Tj ET Q q 0 0 0 rg BT 82.37 273.10 Td (is ) Tj ET Q q 0 0 0 rg BT 91.41 273.10 Td (no ) Tj ET Q q 0 0 0 rg BT 103.77 273.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 143.34 273.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 189.01 273.10 Td (with ) Tj ET Q q 0 0 0 rg BT 209.15 273.10 Td (products ) Tj ET Q q 0 0 0 rg BT 245.95 273.10 Td (in ) Tj ET Q q 0 0 0 rg BT 256.09 273.10 Td (a ) Tj ET Q q 0 0 0 rg BT 262.89 273.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 293.03 273.10 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 339.81 273.10 Td (category ) Tj ET Q q 0 0 0 rg BT 376.60 273.10 Td (or ) Tj ET Q q 0 0 0 rg BT 387.29 273.10 Td (with ) Tj ET Q q 0 0 0 rg BT 407.44 273.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 437.57 273.10 Td (operational ) Tj ET Q q 0 0 0 rg BT 484.92 273.10 Td (characteristics, ) Tj ET Q q 0 0 0 rg BT 546.97 273.10 Td (or ) Tj ET Q q 0 0 0 rg BT 557.66 273.10 Td (until ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 261.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 261.10 Td (right ) Tj ET Q q 0 0 0 rg BT 72.10 261.10 Td (of ) Tj ET Q q 0 0 0 rg BT 82.93 261.10 Td (return ) Tj ET Q q 0 0 0 rg BT 109.31 261.10 Td (no ) Tj ET Q q 0 0 0 rg BT 121.81 261.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 149.86 261.10 Td (exists ) Tj ET Q q 0 0 0 rg BT 175.14 261.10 Td (or ) Tj ET Q q 0 0 0 rg BT 185.97 261.10 Td (suf) Tj ET Q q 0 0 0 rg BT 198.01 261.10 Td (ficient ) Tj ET Q q 0 0 0 rg BT 226.05 261.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 265.76 261.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 311.56 261.10 Td (to ) Tj ET Q q 0 0 0 rg BT 321.84 261.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 357.66 261.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 379.60 261.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 409.87 261.10 Td (is ) Tj ET Q q 0 0 0 rg BT 419.04 261.10 Td (developed.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 237.10 Td (Income ) Tj ET Q q 0 0 0 rg BT 69.98 237.10 Td (T) Tj ET Q q 0 0 0 rg BT 75.73 237.10 Td (axes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.21 217.10 Td (provision ) Tj ET Q q 0 0 0 rg BT 94.65 217.10 Td (for ) Tj ET Q q 0 0 0 rg BT 108.97 217.10 Td (income ) Tj ET Q q 0 0 0 rg BT 141.06 217.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 164.27 217.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 200.26 217.10 Td (income ) Tj ET Q q 0 0 0 rg BT 232.35 217.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 255.56 217.10 Td (paid ) Tj ET Q q 0 0 0 rg BT 275.44 217.10 Td (or ) Tj ET Q q 0 0 0 rg BT 286.43 217.10 Td (payable ) Tj ET Q q 0 0 0 rg BT 320.18 217.10 Td (for ) Tj ET Q q 0 0 0 rg BT 334.51 217.10 Td (the ) Tj ET Q q 0 0 0 rg BT 349.38 217.10 Td (current ) Tj ET Q q 0 0 0 rg BT 380.36 217.10 Td (year ) Tj ET Q q 0 0 0 rg BT 400.23 217.10 Td (plus ) Tj ET Q q 0 0 0 rg BT 419.56 217.10 Td (the ) Tj ET Q q 0 0 0 rg BT 434.44 217.10 Td (change ) Tj ET Q q 0 0 0 rg BT 465.41 217.10 Td (in ) Tj ET Q q 0 0 0 rg BT 475.85 217.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 511.82 217.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 535.03 217.10 Td (during ) Tj ET Q q 0 0 0 rg BT 563.80 217.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 205.10 Td (year) Tj ET Q q 0 0 0 rg BT 52.66 205.10 Td (. ) Tj ET Q q 0 0 0 rg BT 57.86 205.10 Td (Deferred ) Tj ET Q q 0 0 0 rg BT 96.09 205.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 119.34 205.10 Td (result ) Tj ET Q q 0 0 0 rg BT 144.26 205.10 Td (from ) Tj ET Q q 0 0 0 rg BT 166.41 205.10 Td (dif) Tj ET Q q 0 0 0 rg BT 177.33 205.10 Td (ferences ) Tj ET Q q 0 0 0 rg BT 213.34 205.10 Td (between ) Tj ET Q q 0 0 0 rg BT 249.36 205.10 Td (the ) Tj ET Q q 0 0 0 rg BT 264.28 205.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 301.97 205.10 Td (and ) Tj ET Q q 0 0 0 rg BT 319.11 205.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 334.03 205.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 356.74 205.10 Td (of ) Tj ET Q q 0 0 0 rg BT 367.77 205.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 393.80 205.10 Td (and ) Tj ET Q q 0 0 0 rg BT 410.95 205.10 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 450.87 205.10 Td (and ) Tj ET Q q 0 0 0 rg BT 468.01 205.10 Td (are ) Tj ET Q q 0 0 0 rg BT 482.92 205.10 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 518.95 205.10 Td (for ) Tj ET Q q 0 0 0 rg BT 533.31 205.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 568.23 205.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 193.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.29 193.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 71.25 193.10 Td (and ) Tj ET Q q 0 0 0 rg BT 87.76 193.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 102.06 193.10 Td (laws ) Tj ET Q q 0 0 0 rg BT 122.46 193.10 Td (when ) Tj ET Q q 0 0 0 rg BT 146.20 193.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 180.48 193.10 Td (are ) Tj ET Q q 0 0 0 rg BT 194.77 193.10 Td (enacted. ) Tj ET Q q 0 0 0 rg BT 229.73 193.10 Td (V) Tj ET Q q 0 0 0 rg BT 235.84 193.10 Td (aluation ) Tj ET Q q 0 0 0 rg BT 270.13 193.10 Td (allowances ) Tj ET Q q 0 0 0 rg BT 316.63 193.10 Td (are ) Tj ET Q q 0 0 0 rg BT 330.91 193.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 376.85 193.10 Td (to ) Tj ET Q q 0 0 0 rg BT 386.71 193.10 Td (reduce ) Tj ET Q q 0 0 0 rg BT 415.43 193.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 450.81 193.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 465.10 193.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 490.51 193.10 Td (when ) Tj ET Q q 0 0 0 rg BT 514.25 193.10 Td (it ) Tj ET Q q 0 0 0 rg BT 521.88 193.10 Td (is ) Tj ET Q q 0 0 0 rg BT 530.63 193.10 Td (more ) Tj ET Q q 0 0 0 rg BT 553.25 193.10 Td (likely ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.10 Td (than ) Tj ET Q q 0 0 0 rg BT 54.96 181.10 Td (not ) Tj ET Q q 0 0 0 rg BT 69.48 181.10 Td (that ) Tj ET Q q 0 0 0 rg BT 86.21 181.10 Td (a ) Tj ET Q q 0 0 0 rg BT 92.39 181.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 106.35 181.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 135.85 181.10 Td (will ) Tj ET Q q 0 0 0 rg BT 153.15 181.10 Td (not ) Tj ET Q q 0 0 0 rg BT 167.67 181.10 Td (be ) Tj ET Q q 0 0 0 rg BT 178.85 181.10 Td (realized. ) Tj ET Q q 0 0 0 rg BT 214.60 181.10 Td (The ) Tj ET Q q 0 0 0 rg BT 231.89 181.10 Td (assessment ) Tj ET Q q 0 0 0 rg BT 278.07 181.10 Td (of ) Tj ET Q q 0 0 0 rg BT 288.14 181.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 322.09 181.10 Td (or ) Tj ET Q q 0 0 0 rg BT 332.16 181.10 Td (not ) Tj ET Q q 0 0 0 rg BT 346.68 181.10 Td (a ) Tj ET Q q 0 0 0 rg BT 352.86 181.10 Td (valuation ) Tj ET Q q 0 0 0 rg BT 391.81 181.10 Td (allowance ) Tj ET Q q 0 0 0 rg BT 434.08 181.10 Td (is ) Tj ET Q q 0 0 0 rg BT 442.50 181.10 Td (required ) Tj ET Q q 0 0 0 rg BT 477.55 181.10 Td (often ) Tj ET Q q 0 0 0 rg BT 499.84 181.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 533.79 181.10 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 169.10 Td (judgment ) Tj ET Q q 0 0 0 rg BT 76.61 169.10 Td (including ) Tj ET Q q 0 0 0 rg BT 117.22 169.10 Td (the ) Tj ET Q q 0 0 0 rg BT 132.27 169.10 Td (long-range ) Tj ET Q q 0 0 0 rg BT 178.43 169.10 Td (forecast ) Tj ET Q q 0 0 0 rg BT 212.91 169.10 Td (of ) Tj ET Q q 0 0 0 rg BT 224.08 169.10 Td (future ) Tj ET Q q 0 0 0 rg BT 250.79 169.10 Td (taxable ) Tj ET Q q 0 0 0 rg BT 282.50 169.10 Td (income ) Tj ET Q q 0 0 0 rg BT 314.77 169.10 Td (and ) Tj ET Q q 0 0 0 rg BT 332.04 169.10 Td (the ) Tj ET Q q 0 0 0 rg BT 347.10 169.10 Td (evaluation ) Tj ET Q q 0 0 0 rg BT 391.59 169.10 Td (of ) Tj ET Q q 0 0 0 rg BT 402.75 169.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 417.81 169.10 Td (planning ) Tj ET Q q 0 0 0 rg BT 455.64 169.10 Td (initiatives. ) Tj ET Q q 0 0 0 rg BT 499.79 169.10 Td (Adjustments ) Tj ET Q q 0 0 0 rg BT 553.18 169.10 Td (to ) Tj ET Q q 0 0 0 rg BT 563.80 169.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 157.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 71.81 157.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 86.52 157.10 Td (valuation ) Tj ET Q q 0 0 0 rg BT 126.23 157.10 Td (allowances ) Tj ET Q q 0 0 0 rg BT 173.16 157.10 Td (are ) Tj ET Q q 0 0 0 rg BT 187.87 157.10 Td (made ) Tj ET Q q 0 0 0 rg BT 212.02 157.10 Td (to ) Tj ET Q q 0 0 0 rg BT 222.30 157.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 258.68 157.10 Td (in ) Tj ET Q q 0 0 0 rg BT 268.95 157.10 Td (the ) Tj ET Q q 0 0 0 rg BT 283.67 157.10 Td (period ) Tj ET Q q 0 0 0 rg BT 311.72 157.10 Td (when ) Tj ET Q q 0 0 0 rg BT 335.88 157.10 Td (such ) Tj ET Q q 0 0 0 rg BT 356.71 157.10 Td (assessments ) Tj ET Q q 0 0 0 rg BT 407.54 157.10 Td (are ) Tj ET Q q 0 0 0 rg BT 422.25 157.10 Td (made.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 133.10 Td (T) Tj ET Q q 0 0 0 rg BT 41.41 133.10 Td (ax ) Tj ET Q q 0 0 0 rg BT 53.92 133.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 88.64 133.10 Td (are ) Tj ET Q q 0 0 0 rg BT 103.91 133.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 150.84 133.10 Td (from ) Tj ET Q q 0 0 0 rg BT 173.35 133.10 Td (an ) Tj ET Q q 0 0 0 rg BT 185.86 133.10 Td (uncertain ) Tj ET Q q 0 0 0 rg BT 226.13 133.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 241.41 133.10 Td (position ) Tj ET Q q 0 0 0 rg BT 276.71 133.10 Td (only ) Tj ET Q q 0 0 0 rg BT 297.55 133.10 Td (if ) Tj ET Q q 0 0 0 rg BT 306.73 133.10 Td (it ) Tj ET Q q 0 0 0 rg BT 315.35 133.10 Td (is ) Tj ET Q q 0 0 0 rg BT 325.09 133.10 Td (more ) Tj ET Q q 0 0 0 rg BT 348.71 133.10 Td (likely ) Tj ET Q q 0 0 0 rg BT 374.55 133.10 Td (than ) Tj ET Q q 0 0 0 rg BT 394.83 133.10 Td (not ) Tj ET Q q 0 0 0 rg BT 410.68 133.10 Td (that ) Tj ET Q q 0 0 0 rg BT 428.74 133.10 Td (the ) Tj ET Q q 0 0 0 rg BT 444.03 133.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 459.31 133.10 Td (position ) Tj ET Q q 0 0 0 rg BT 494.60 133.10 Td (will ) Tj ET Q q 0 0 0 rg BT 513.23 133.10 Td (be ) Tj ET Q q 0 0 0 rg BT 525.74 133.10 Td (sustained ) Tj ET Q q 0 0 0 rg BT 566.02 133.10 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 121.10 Td (examination ) Tj ET Q q 0 0 0 rg BT 87.60 121.10 Td (by ) Tj ET Q q 0 0 0 rg BT 99.77 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 114.15 121.10 Td (taxing ) Tj ET Q q 0 0 0 rg BT 141.32 121.10 Td (authorities ) Tj ET Q q 0 0 0 rg BT 185.70 121.10 Td (based ) Tj ET Q q 0 0 0 rg BT 210.64 121.10 Td (on ) Tj ET Q q 0 0 0 rg BT 222.81 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 237.19 121.10 Td (technical ) Tj ET Q q 0 0 0 rg BT 275.45 121.10 Td (merits ) Tj ET Q q 0 0 0 rg BT 302.62 121.10 Td (of ) Tj ET Q q 0 0 0 rg BT 313.12 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 327.50 121.10 Td (position. ) Tj ET Q q 0 0 0 rg BT 364.24 121.10 Td (The ) Tj ET Q q 0 0 0 rg BT 381.96 121.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 396.34 121.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 426.28 121.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 472.31 121.10 Td (in ) Tj ET Q q 0 0 0 rg BT 482.26 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 496.64 121.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 533.79 121.10 Td (statements ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 109.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 109.10 Td (a ) Tj ET Q q 0 0 0 rg BT 57.10 109.10 Td (particular ) Tj ET Q q 0 0 0 rg BT 97.91 109.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 112.63 109.10 Td (position ) Tj ET Q q 0 0 0 rg BT 147.35 109.10 Td (is ) Tj ET Q q 0 0 0 rg BT 156.52 109.10 Td (based ) Tj ET Q q 0 0 0 rg BT 181.79 109.10 Td (on ) Tj ET Q q 0 0 0 rg BT 194.29 109.10 Td (the ) Tj ET Q q 0 0 0 rg BT 209.01 109.10 Td (lar) Tj ET Q q 0 0 0 rg BT 219.37 109.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 237.98 109.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 268.25 109.10 Td (that ) Tj ET Q q 0 0 0 rg BT 285.74 109.10 Td (is ) Tj ET Q q 0 0 0 rg BT 294.91 109.10 Td (more ) Tj ET Q q 0 0 0 rg BT 317.96 109.10 Td (likely ) Tj ET Q q 0 0 0 rg BT 343.23 109.10 Td (than ) Tj ET Q q 0 0 0 rg BT 362.95 109.10 Td (not ) Tj ET Q q 0 0 0 rg BT 378.23 109.10 Td (to ) Tj ET Q q 0 0 0 rg BT 388.50 109.10 Td (be ) Tj ET Q q 0 0 0 rg BT 400.44 109.10 Td (realized ) Tj ET Q q 0 0 0 rg BT 434.58 109.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 457.08 109.10 Td (settlement.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 85.10 Td (Cash and Cash Equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 65.10 Td (Cash ) Tj ET Q q 0 0 0 rg BT 58.21 65.10 Td (and ) Tj ET Q q 0 0 0 rg BT 74.87 65.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 94.85 65.10 Td (equivalents ) Tj ET Q q 0 0 0 rg BT 142.61 65.10 Td (include ) Tj ET Q q 0 0 0 rg BT 174.25 65.10 Td (bank ) Tj ET Q q 0 0 0 rg BT 195.91 65.10 Td (deposits, ) Tj ET Q q 0 0 0 rg BT 233.40 65.10 Td (time ) Tj ET Q q 0 0 0 rg BT 253.39 65.10 Td (deposits, ) Tj ET Q q 0 0 0 rg BT 290.88 65.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 340.29 65.10 Td (paper ) Tj ET Q q 0 0 0 rg BT 364.71 65.10 Td (and ) Tj ET Q q 0 0 0 rg BT 381.37 65.10 Td (money ) Tj ET Q q 0 0 0 rg BT 410.80 65.10 Td (market ) Tj ET Q q 0 0 0 rg BT 440.78 65.10 Td (funds. ) Tj ET Q q 0 0 0 rg BT 467.71 65.10 Td (Cash ) Tj ET Q q 0 0 0 rg BT 489.93 65.10 Td (equivalents ) Tj ET Q q 0 0 0 rg BT 537.68 65.10 Td (consist ) Tj ET Q q 0 0 0 rg BT 567.67 65.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 53.10 Td (highly ) Tj ET Q q 0 0 0 rg BT 64.96 53.10 Td (liquid ) Tj ET Q q 0 0 0 rg BT 91.70 53.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 142.88 53.10 Td (with ) Tj ET Q q 0 0 0 rg BT 164.07 53.10 Td (original ) Tj ET Q q 0 0 0 rg BT 198.58 53.10 Td (maturities ) Tj ET Q q 0 0 0 rg BT 241.97 53.10 Td (of ) Tj ET Q q 0 0 0 rg BT 253.71 53.10 Td (three ) Tj ET Q q 0 0 0 rg BT 277.10 53.10 Td (months ) Tj ET Q q 0 0 0 rg BT 309.95 53.10 Td (or ) Tj ET Q q 0 0 0 rg BT 321.69 53.10 Td (less ) Tj ET Q q 0 0 0 rg BT 340.09 53.10 Td (at ) Tj ET Q q 0 0 0 rg BT 350.72 53.10 Td (the ) Tj ET Q q 0 0 0 rg BT 366.34 53.10 Td (time ) Tj ET Q q 0 0 0 rg BT 387.52 53.10 Td (of ) Tj ET Q q 0 0 0 rg BT 399.25 53.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 438.20 53.10 Td (and ) Tj ET Q q 0 0 0 rg BT 456.04 53.10 Td (are ) Tj ET Q q 0 0 0 rg BT 471.65 53.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 518.92 53.10 Td (at ) Tj ET Q q 0 0 0 rg BT 529.54 53.10 Td (cost, ) Tj ET Q q 0 0 0 rg BT 551.56 53.10 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 41.10 Td (approximates ) Tj ET Q q 0 0 0 rg BT 92.37 41.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 108.75 41.10 Td (value.) Tj ET Q endstream endobj 123 0 obj <> endobj 124 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (61) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (Marketable ) Tj ET Q q 0 0 0 rg BT 88.49 737.25 Td (Securities ) Tj ET Q q 0 0 0 rg BT 132.64 737.25 Td (and ) Tj ET Q q 0 0 0 rg BT 151.26 737.25 Td (Investments ) Tj ET Q q 0 0 0 rg BT 205.43 737.25 Td (in ) Tj ET Q q 0 0 0 rg BT 216.27 737.25 Td (Other) Tj ET Q q 0 0 0 rg BT 241.63 737.25 Td ( ) Tj ET Q q 0 0 0 rg BT 244.13 737.25 Td (Companies) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 717.25 Td (Marketable ) Tj ET Q q 0 0 0 rg BT 84.41 717.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 125.05 717.25 Td (are ) Tj ET Q q 0 0 0 rg BT 140.13 717.25 Td (classified ) Tj ET Q q 0 0 0 rg BT 180.77 717.25 Td (as ) Tj ET Q q 0 0 0 rg BT 191.97 717.25 Td (“available-for) Tj ET Q q 0 0 0 rg BT 247.29 717.25 Td (-sale” ) Tj ET Q q 0 0 0 rg BT 273.48 717.25 Td (on ) Tj ET Q q 0 0 0 rg BT 286.35 717.25 Td (the ) Tj ET Q q 0 0 0 rg BT 301.45 717.25 Td (date ) Tj ET Q q 0 0 0 rg BT 320.98 717.25 Td (of ) Tj ET Q q 0 0 0 rg BT 332.18 717.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 370.59 717.25 Td (and ) Tj ET Q q 0 0 0 rg BT 387.91 717.25 Td (reported ) Tj ET Q q 0 0 0 rg BT 424.10 717.25 Td (at ) Tj ET Q q 0 0 0 rg BT 434.19 717.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 450.94 717.25 Td (value. ) Tj ET Q q 0 0 0 rg BT 477.97 717.25 Td (Fair ) Tj ET Q q 0 0 0 rg BT 496.96 717.25 Td (value ) Tj ET Q q 0 0 0 rg BT 521.49 717.25 Td (is ) Tj ET Q q 0 0 0 rg BT 531.03 717.25 Td (determined ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 705.25 Td (based ) Tj ET Q q 0 0 0 rg BT 62.55 705.25 Td (on ) Tj ET Q q 0 0 0 rg BT 76.33 705.25 Td (observable ) Tj ET Q q 0 0 0 rg BT 123.43 705.25 Td (market ) Tj ET Q q 0 0 0 rg BT 154.98 705.25 Td (quotes ) Tj ET Q q 0 0 0 rg BT 184.87 705.25 Td (or ) Tj ET Q q 0 0 0 rg BT 196.98 705.25 Td (valuation ) Tj ET Q q 0 0 0 rg BT 237.97 705.25 Td (models ) Tj ET Q q 0 0 0 rg BT 270.64 705.25 Td (using ) Tj ET Q q 0 0 0 rg BT 296.09 705.25 Td (assessments ) Tj ET Q q 0 0 0 rg BT 348.21 705.25 Td (of ) Tj ET Q q 0 0 0 rg BT 360.32 705.25 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 414.63 705.25 Td (credit ) Tj ET Q q 0 0 0 rg BT 441.18 705.25 Td (worthiness, ) Tj ET Q q 0 0 0 rg BT 490.79 705.25 Td (credit ) Tj ET Q q 0 0 0 rg BT 517.34 705.25 Td (default ) Tj ET Q q 0 0 0 rg BT 548.88 705.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 567.67 705.25 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 693.25 Td (underlying ) Tj ET Q q 0 0 0 rg BT 81.83 693.25 Td (security ) Tj ET Q q 0 0 0 rg BT 115.98 693.25 Td (and ) Tj ET Q q 0 0 0 rg BT 132.92 693.25 Td (overall ) Tj ET Q q 0 0 0 rg BT 163.18 693.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 192.33 693.25 Td (market ) Tj ET Q q 0 0 0 rg BT 222.60 693.25 Td (liquidity) Tj ET Q q 0 0 0 rg BT 255.84 693.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 669.25 Td (Investments ) Tj ET Q q 0 0 0 rg BT 87.69 669.25 Td (in ) Tj ET Q q 0 0 0 rg BT 98.84 669.25 Td (50% ) Tj ET Q q 0 0 0 rg BT 120.54 669.25 Td (or ) Tj ET Q q 0 0 0 rg BT 132.24 669.25 Td (less ) Tj ET Q q 0 0 0 rg BT 150.61 669.25 Td (owned ) Tj ET Q q 0 0 0 rg BT 180.64 669.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 226.77 669.25 Td (are ) Tj ET Q q 0 0 0 rg BT 242.35 669.25 Td (accounted ) Tj ET Q q 0 0 0 rg BT 286.25 669.25 Td (for ) Tj ET Q q 0 0 0 rg BT 301.28 669.25 Td (using ) Tj ET Q q 0 0 0 rg BT 326.32 669.25 Td (the ) Tj ET Q q 0 0 0 rg BT 341.90 669.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 370.27 669.25 Td (method ) Tj ET Q q 0 0 0 rg BT 403.63 669.25 Td (of ) Tj ET Q q 0 0 0 rg BT 415.33 669.25 Td (accounting ) Tj ET Q q 0 0 0 rg BT 462.57 669.25 Td (when ) Tj ET Q q 0 0 0 rg BT 487.60 669.25 Td (the ) Tj ET Q q 0 0 0 rg BT 503.19 669.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 532.11 669.25 Td (to ) Tj ET Q q 0 0 0 rg BT 543.26 669.25 Td (exercise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 657.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 81.23 657.25 Td (influence ) Tj ET Q q 0 0 0 rg BT 121.45 657.25 Td (is ) Tj ET Q q 0 0 0 rg BT 131.14 657.25 Td (maintained. ) Tj ET Q q 0 0 0 rg BT 180.86 657.25 Td (The ) Tj ET Q q 0 0 0 rg BT 199.43 657.25 Td (share ) Tj ET Q q 0 0 0 rg BT 223.55 657.25 Td (of ) Tj ET Q q 0 0 0 rg BT 234.89 657.25 Td (net ) Tj ET Q q 0 0 0 rg BT 250.13 657.25 Td (income ) Tj ET Q q 0 0 0 rg BT 282.58 657.25 Td (or ) Tj ET Q q 0 0 0 rg BT 293.93 657.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 320.84 657.25 Td (of ) Tj ET Q q 0 0 0 rg BT 332.18 657.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 360.20 657.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 410.99 657.25 Td (is ) Tj ET Q q 0 0 0 rg BT 420.67 657.25 Td (included ) Tj ET Q q 0 0 0 rg BT 458.13 657.25 Td (in ) Tj ET Q q 0 0 0 rg BT 468.92 657.25 Td (other ) Tj ET Q q 0 0 0 rg BT 492.49 657.25 Td (income ) Tj ET Q q 0 0 0 rg BT 524.94 657.25 Td (\(net\). ) Tj ET Q q 0 0 0 rg BT 549.33 657.25 Td (Equity ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 645.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 86.19 645.25 Td (are ) Tj ET Q q 0 0 0 rg BT 100.81 645.25 Td (reviewed ) Tj ET Q q 0 0 0 rg BT 139.87 645.25 Td (for ) Tj ET Q q 0 0 0 rg BT 153.95 645.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 202.46 645.25 Td (by ) Tj ET Q q 0 0 0 rg BT 214.88 645.25 Td (assessing ) Tj ET Q q 0 0 0 rg BT 254.52 645.25 Td (if ) Tj ET Q q 0 0 0 rg BT 263.04 645.25 Td (the ) Tj ET Q q 0 0 0 rg BT 277.68 645.25 Td (decline ) Tj ET Q q 0 0 0 rg BT 308.96 645.25 Td (in ) Tj ET Q q 0 0 0 rg BT 319.16 645.25 Td (market ) Tj ET Q q 0 0 0 rg BT 349.34 645.25 Td (value ) Tj ET Q q 0 0 0 rg BT 373.41 645.25 Td (of ) Tj ET Q q 0 0 0 rg BT 384.16 645.25 Td (the ) Tj ET Q q 0 0 0 rg BT 398.79 645.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 445.09 645.25 Td (below ) Tj ET Q q 0 0 0 rg BT 471.94 645.25 Td (the ) Tj ET Q q 0 0 0 rg BT 486.57 645.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 522.30 645.25 Td (value ) Tj ET Q q 0 0 0 rg BT 546.38 645.25 Td (is ) Tj ET Q q 0 0 0 rg BT 555.46 645.25 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 633.25 Td (than ) Tj ET Q q 0 0 0 rg BT 55.52 633.25 Td (temporary) Tj ET Q q 0 0 0 rg BT 95.97 633.25 Td (, ) Tj ET Q q 0 0 0 rg BT 100.77 633.25 Td (which ) Tj ET Q q 0 0 0 rg BT 127.52 633.25 Td (considers ) Tj ET Q q 0 0 0 rg BT 167.59 633.25 Td (the ) Tj ET Q q 0 0 0 rg BT 182.12 633.25 Td (intent ) Tj ET Q q 0 0 0 rg BT 207.20 633.25 Td (and ) Tj ET Q q 0 0 0 rg BT 223.94 633.25 Td (ability ) Tj ET Q q 0 0 0 rg BT 251.80 633.25 Td (to ) Tj ET Q q 0 0 0 rg BT 261.88 633.25 Td (retain ) Tj ET Q q 0 0 0 rg BT 286.95 633.25 Td (the ) Tj ET Q q 0 0 0 rg BT 301.48 633.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 347.66 633.25 Td (for ) Tj ET Q q 0 0 0 rg BT 361.63 633.25 Td (a ) Tj ET Q q 0 0 0 rg BT 368.37 633.25 Td (period ) Tj ET Q q 0 0 0 rg BT 396.23 633.25 Td (of ) Tj ET Q q 0 0 0 rg BT 406.86 633.25 Td (time ) Tj ET Q q 0 0 0 rg BT 426.94 633.25 Td (suf) Tj ET Q q 0 0 0 rg BT 438.98 633.25 Td (ficient ) Tj ET Q q 0 0 0 rg BT 466.83 633.25 Td (to ) Tj ET Q q 0 0 0 rg BT 476.92 633.25 Td (allow ) Tj ET Q q 0 0 0 rg BT 501.44 633.25 Td (for ) Tj ET Q q 0 0 0 rg BT 515.41 633.25 Td (any ) Tj ET Q q 0 0 0 rg BT 532.15 633.25 Td (anticipated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.25 Td (recovery ) Tj ET Q q 0 0 0 rg BT 73.48 621.25 Td (in ) Tj ET Q q 0 0 0 rg BT 83.75 621.25 Td (market ) Tj ET Q q 0 0 0 rg BT 114.02 621.25 Td (value, ) Tj ET Q q 0 0 0 rg BT 140.67 621.25 Td (the ) Tj ET Q q 0 0 0 rg BT 155.39 621.25 Td (duration ) Tj ET Q q 0 0 0 rg BT 191.21 621.25 Td (and ) Tj ET Q q 0 0 0 rg BT 208.15 621.25 Td (extent ) Tj ET Q q 0 0 0 rg BT 235.09 621.25 Td (that ) Tj ET Q q 0 0 0 rg BT 252.58 621.25 Td (the ) Tj ET Q q 0 0 0 rg BT 267.30 621.25 Td (market ) Tj ET Q q 0 0 0 rg BT 297.56 621.25 Td (value ) Tj ET Q q 0 0 0 rg BT 321.72 621.25 Td (has ) Tj ET Q q 0 0 0 rg BT 337.55 621.25 Td (been ) Tj ET Q q 0 0 0 rg BT 358.92 621.25 Td (less ) Tj ET Q q 0 0 0 rg BT 376.42 621.25 Td (than ) Tj ET Q q 0 0 0 rg BT 396.14 621.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 414.75 621.25 Td (and ) Tj ET Q q 0 0 0 rg BT 431.69 621.25 Td (the ) Tj ET Q q 0 0 0 rg BT 446.41 621.25 Td (investee's ) Tj ET Q q 0 0 0 rg BT 487.36 621.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 524.84 621.25 Td (condition.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 597.25 Td (Inventory ) Tj ET Q q 0 0 0 rg BT 80.54 597.25 Td (V) Tj ET Q q 0 0 0 rg BT 86.84 597.25 Td (aluation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 577.25 Td (Inventories ) Tj ET Q q 0 0 0 rg BT 83.49 577.25 Td (are ) Tj ET Q q 0 0 0 rg BT 98.19 577.25 Td (stated ) Tj ET Q q 0 0 0 rg BT 124.02 577.25 Td (at ) Tj ET Q q 0 0 0 rg BT 133.73 577.25 Td (the ) Tj ET Q q 0 0 0 rg BT 148.45 577.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 173.72 577.25 Td (of ) Tj ET Q q 0 0 0 rg BT 184.55 577.25 Td (average ) Tj ET Q q 0 0 0 rg BT 218.13 577.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 236.74 577.25 Td (or ) Tj ET Q q 0 0 0 rg BT 247.57 577.25 Td (market.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 553.25 Td (Pr) Tj ET Q q 0 0 0 rg BT 46.37 553.25 Td (operty) Tj ET Q q 0 0 0 rg BT 73.58 553.25 Td (, Plant and Equipment and Depr) Tj ET Q q 0 0 0 rg BT 212.88 553.25 Td (eciation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (Expenditures ) Tj ET Q q 0 0 0 rg BT 90.80 533.25 Td (for ) Tj ET Q q 0 0 0 rg BT 104.50 533.25 Td (additions, ) Tj ET Q q 0 0 0 rg BT 145.70 533.25 Td (renewals ) Tj ET Q q 0 0 0 rg BT 183.27 533.25 Td (and ) Tj ET Q q 0 0 0 rg BT 199.75 533.25 Td (improvements ) Tj ET Q q 0 0 0 rg BT 258.99 533.25 Td (are ) Tj ET Q q 0 0 0 rg BT 273.24 533.25 Td (capitalized ) Tj ET Q q 0 0 0 rg BT 318.58 533.25 Td (at ) Tj ET Q q 0 0 0 rg BT 327.83 533.25 Td (cost. ) Tj ET Q q 0 0 0 rg BT 348.48 533.25 Td (Depreciation ) Tj ET Q q 0 0 0 rg BT 402.15 533.25 Td (is ) Tj ET Q q 0 0 0 rg BT 410.86 533.25 Td (computed ) Tj ET Q q 0 0 0 rg BT 452.33 533.25 Td (on ) Tj ET Q q 0 0 0 rg BT 464.36 533.25 Td (a ) Tj ET Q q 0 0 0 rg BT 470.84 533.25 Td (straight-line ) Tj ET Q q 0 0 0 rg BT 521.20 533.25 Td (method ) Tj ET Q q 0 0 0 rg BT 553.23 533.25 Td (based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 521.25 Td (on ) Tj ET Q q 0 0 0 rg BT 48.55 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 63.31 521.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 104.17 521.25 Td (useful ) Tj ET Q q 0 0 0 rg BT 131.16 521.25 Td (lives ) Tj ET Q q 0 0 0 rg BT 152.59 521.25 Td (of ) Tj ET Q q 0 0 0 rg BT 163.46 521.25 Td (the ) Tj ET Q q 0 0 0 rg BT 178.23 521.25 Td (related ) Tj ET Q q 0 0 0 rg BT 207.97 521.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 233.85 521.25 Td (ranging ) Tj ET Q q 0 0 0 rg BT 266.94 521.25 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.93 521.25 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.93 521.25 Td ( ) Tj ET Q q 0 0 0 rg BT 301.47 521.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 311.80 521.25 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.80 521.25 Td ( ) Tj ET Q q 0 0 0 rg BT 324.34 521.25 Td (years ) Tj ET Q q 0 0 0 rg BT 347.98 521.25 Td (for ) Tj ET Q q 0 0 0 rg BT 362.19 521.25 Td (buildings ) Tj ET Q q 0 0 0 rg BT 401.96 521.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.95 521.25 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.95 521.25 Td ( ) Tj ET Q q 0 0 0 rg BT 426.49 521.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.82 521.25 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.82 521.25 Td ( ) Tj ET Q q 0 0 0 rg BT 449.36 521.25 Td (years ) Tj ET Q q 0 0 0 rg BT 473.00 521.25 Td (for ) Tj ET Q q 0 0 0 rg BT 487.21 521.25 Td (machinery) Tj ET Q q 0 0 0 rg BT 528.76 521.25 Td (, ) Tj ET Q q 0 0 0 rg BT 533.81 521.25 Td (equipment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 509.25 Td (fixtures.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (Impairment of Long-Lived ) Tj ET Q q 0 0 0 rg BT 152.95 485.25 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 465.25 Td (Current ) Tj ET Q q 0 0 0 rg BT 68.65 465.25 Td (facts ) Tj ET Q q 0 0 0 rg BT 89.63 465.25 Td (or ) Tj ET Q q 0 0 0 rg BT 100.06 465.25 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 158.80 465.25 Td (are ) Tj ET Q q 0 0 0 rg BT 173.11 465.25 Td (periodically ) Tj ET Q q 0 0 0 rg BT 222.97 465.25 Td (evaluated ) Tj ET Q q 0 0 0 rg BT 263.38 465.25 Td (to ) Tj ET Q q 0 0 0 rg BT 273.26 465.25 Td (determine ) Tj ET Q q 0 0 0 rg BT 315.34 465.25 Td (if ) Tj ET Q q 0 0 0 rg BT 323.55 465.25 Td (the ) Tj ET Q q 0 0 0 rg BT 337.87 465.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 373.28 465.25 Td (value ) Tj ET Q q 0 0 0 rg BT 397.04 465.25 Td (of ) Tj ET Q q 0 0 0 rg BT 407.47 465.25 Td (depreciable ) Tj ET Q q 0 0 0 rg BT 455.65 465.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 481.08 465.25 Td (to ) Tj ET Q q 0 0 0 rg BT 490.96 465.25 Td (be ) Tj ET Q q 0 0 0 rg BT 502.50 465.25 Td (held ) Tj ET Q q 0 0 0 rg BT 521.82 465.25 Td (and ) Tj ET Q q 0 0 0 rg BT 538.36 465.25 Td (used ) Tj ET Q q 0 0 0 rg BT 558.79 465.25 Td (may ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.25 Td (not ) Tj ET Q q 0 0 0 rg BT 52.20 453.25 Td (be ) Tj ET Q q 0 0 0 rg BT 65.05 453.25 Td (recoverable. ) Tj ET Q q 0 0 0 rg BT 117.60 453.25 Td (If ) Tj ET Q q 0 0 0 rg BT 127.68 453.25 Td (such ) Tj ET Q q 0 0 0 rg BT 149.42 453.25 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 209.48 453.25 Td (exist, ) Tj ET Q q 0 0 0 rg BT 234.28 453.25 Td (an ) Tj ET Q q 0 0 0 rg BT 247.14 453.25 Td (estimate ) Tj ET Q q 0 0 0 rg BT 283.88 453.25 Td (of ) Tj ET Q q 0 0 0 rg BT 295.62 453.25 Td (undiscounted ) Tj ET Q q 0 0 0 rg BT 352.37 453.25 Td (future ) Tj ET Q q 0 0 0 rg BT 379.66 453.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 400.85 453.25 Td (flows ) Tj ET Q q 0 0 0 rg BT 426.48 453.25 Td (generated ) Tj ET Q q 0 0 0 rg BT 468.76 453.25 Td (by ) Tj ET Q q 0 0 0 rg BT 482.18 453.25 Td (the ) Tj ET Q q 0 0 0 rg BT 497.81 453.25 Td (long-lived ) Tj ET Q q 0 0 0 rg BT 542.33 453.25 Td (asset, ) Tj ET Q q 0 0 0 rg BT 567.69 453.25 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.25 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 82.90 441.25 Td (grouping ) Tj ET Q q 0 0 0 rg BT 120.38 441.25 Td (of ) Tj ET Q q 0 0 0 rg BT 130.08 441.25 Td (assets, ) Tj ET Q q 0 0 0 rg BT 157.29 441.25 Td (is ) Tj ET Q q 0 0 0 rg BT 165.33 441.25 Td (compared ) Tj ET Q q 0 0 0 rg BT 206.12 441.25 Td (to ) Tj ET Q q 0 0 0 rg BT 215.27 441.25 Td (the ) Tj ET Q q 0 0 0 rg BT 228.86 441.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 263.54 441.25 Td (value ) Tj ET Q q 0 0 0 rg BT 286.57 441.25 Td (to ) Tj ET Q q 0 0 0 rg BT 295.72 441.25 Td (determine ) Tj ET Q q 0 0 0 rg BT 337.07 441.25 Td (whether ) Tj ET Q q 0 0 0 rg BT 370.65 441.25 Td (an ) Tj ET Q q 0 0 0 rg BT 381.46 441.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 428.93 441.25 Td (exists ) Tj ET Q q 0 0 0 rg BT 453.08 441.25 Td (at ) Tj ET Q q 0 0 0 rg BT 461.67 441.25 Td (its ) Tj ET Q q 0 0 0 rg BT 472.49 441.25 Td (lowest ) Tj ET Q q 0 0 0 rg BT 499.97 441.25 Td (level ) Tj ET Q q 0 0 0 rg BT 520.77 441.25 Td (of ) Tj ET Q q 0 0 0 rg BT 530.47 441.25 Td (identifiable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 429.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 56.52 429.25 Td (flows. ) Tj ET Q q 0 0 0 rg BT 83.98 429.25 Td (If ) Tj ET Q q 0 0 0 rg BT 93.39 429.25 Td (an ) Tj ET Q q 0 0 0 rg BT 105.58 429.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 127.76 429.25 Td (is ) Tj ET Q q 0 0 0 rg BT 137.18 429.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 184.90 429.25 Td (to ) Tj ET Q q 0 0 0 rg BT 195.43 429.25 Td (be ) Tj ET Q q 0 0 0 rg BT 207.61 429.25 Td (impaired, ) Tj ET Q q 0 0 0 rg BT 248.40 429.25 Td (the ) Tj ET Q q 0 0 0 rg BT 263.37 429.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 281.67 429.25 Td (is ) Tj ET Q q 0 0 0 rg BT 291.09 429.25 Td (measured ) Tj ET Q q 0 0 0 rg BT 332.15 429.25 Td (based ) Tj ET Q q 0 0 0 rg BT 357.67 429.25 Td (on ) Tj ET Q q 0 0 0 rg BT 370.41 429.25 Td (the ) Tj ET Q q 0 0 0 rg BT 385.38 429.25 Td (dif) Tj ET Q q 0 0 0 rg BT 396.31 429.25 Td (ference ) Tj ET Q q 0 0 0 rg BT 428.47 429.25 Td (between ) Tj ET Q q 0 0 0 rg BT 464.53 429.25 Td (the ) Tj ET Q q 0 0 0 rg BT 479.49 429.25 Td (asset’) Tj ET Q q 0 0 0 rg BT 501.71 429.25 Td (s ) Tj ET Q q 0 0 0 rg BT 508.35 429.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 524.97 429.25 Td (value ) Tj ET Q q 0 0 0 rg BT 549.37 429.25 Td (and ) Tj ET Q q 0 0 0 rg BT 566.56 429.25 Td (its ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 417.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 72.27 417.25 Td (value. ) Tj ET Q q 0 0 0 rg BT 98.73 417.25 Td (An ) Tj ET Q q 0 0 0 rg BT 113.91 417.25 Td (estimate ) Tj ET Q q 0 0 0 rg BT 150.18 417.25 Td (of ) Tj ET Q q 0 0 0 rg BT 161.47 417.25 Td (the ) Tj ET Q q 0 0 0 rg BT 176.64 417.25 Td (asset’) Tj ET Q q 0 0 0 rg BT 198.86 417.25 Td (s ) Tj ET Q q 0 0 0 rg BT 205.70 417.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 222.54 417.25 Td (value ) Tj ET Q q 0 0 0 rg BT 247.15 417.25 Td (is ) Tj ET Q q 0 0 0 rg BT 256.77 417.25 Td (based ) Tj ET Q q 0 0 0 rg BT 282.50 417.25 Td (on ) Tj ET Q q 0 0 0 rg BT 295.45 417.25 Td (quoted ) Tj ET Q q 0 0 0 rg BT 325.63 417.25 Td (market ) Tj ET Q q 0 0 0 rg BT 356.34 417.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 383.18 417.25 Td (in ) Tj ET Q q 0 0 0 rg BT 393.91 417.25 Td (active ) Tj ET Q q 0 0 0 rg BT 420.74 417.25 Td (markets, ) Tj ET Q q 0 0 0 rg BT 457.85 417.25 Td (if ) Tj ET Q q 0 0 0 rg BT 466.91 417.25 Td (available. ) Tj ET Q q 0 0 0 rg BT 508.46 417.25 Td (If ) Tj ET Q q 0 0 0 rg BT 518.07 417.25 Td (quoted ) Tj ET Q q 0 0 0 rg BT 548.25 417.25 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 62.27 405.25 Td (are ) Tj ET Q q 0 0 0 rg BT 76.86 405.25 Td (not ) Tj ET Q q 0 0 0 rg BT 92.03 405.25 Td (available, ) Tj ET Q q 0 0 0 rg BT 133.01 405.25 Td (the ) Tj ET Q q 0 0 0 rg BT 147.61 405.25 Td (estimate ) Tj ET Q q 0 0 0 rg BT 183.32 405.25 Td (of ) Tj ET Q q 0 0 0 rg BT 194.04 405.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 210.31 405.25 Td (value ) Tj ET Q q 0 0 0 rg BT 234.35 405.25 Td (is ) Tj ET Q q 0 0 0 rg BT 243.41 405.25 Td (based ) Tj ET Q q 0 0 0 rg BT 268.57 405.25 Td (on ) Tj ET Q q 0 0 0 rg BT 280.96 405.25 Td (various ) Tj ET Q q 0 0 0 rg BT 312.79 405.25 Td (valuation ) Tj ET Q q 0 0 0 rg BT 352.39 405.25 Td (techniques ) Tj ET Q q 0 0 0 rg BT 397.54 405.25 Td (using ) Tj ET Q q 0 0 0 rg BT 421.60 405.25 Td (unobservable ) Tj ET Q q 0 0 0 rg BT 477.30 405.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 493.57 405.25 Td (value ) Tj ET Q q 0 0 0 rg BT 517.61 405.25 Td (inputs, ) Tj ET Q q 0 0 0 rg BT 546.95 405.25 Td (such ) Tj ET Q q 0 0 0 rg BT 567.67 405.25 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 393.25 Td (a ) Tj ET Q q 0 0 0 rg BT 42.94 393.25 Td (discounted ) Tj ET Q q 0 0 0 rg BT 88.76 393.25 Td (value ) Tj ET Q q 0 0 0 rg BT 112.92 393.25 Td (of ) Tj ET Q q 0 0 0 rg BT 123.75 393.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 164.57 393.25 Td (future ) Tj ET Q q 0 0 0 rg BT 190.95 393.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 211.21 393.25 Td (flows.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 369.25 Td (Capitalized Softwar) Tj ET Q q 0 0 0 rg BT 121.09 369.25 Td (e) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.25 Td (Eligible ) Tj ET Q q 0 0 0 rg BT 70.16 349.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 92.66 349.25 Td (to ) Tj ET Q q 0 0 0 rg BT 102.94 349.25 Td (obtain ) Tj ET Q q 0 0 0 rg BT 130.43 349.25 Td (internal ) Tj ET Q q 0 0 0 rg BT 163.48 349.25 Td (use ) Tj ET Q q 0 0 0 rg BT 179.31 349.25 Td (software ) Tj ET Q q 0 0 0 rg BT 216.23 349.25 Td (are ) Tj ET Q q 0 0 0 rg BT 230.94 349.25 Td (capitalized ) Tj ET Q q 0 0 0 rg BT 276.75 349.25 Td (and ) Tj ET Q q 0 0 0 rg BT 293.69 349.25 Td (amortized ) Tj ET Q q 0 0 0 rg BT 336.17 349.25 Td (over ) Tj ET Q q 0 0 0 rg BT 356.43 349.25 Td (the ) Tj ET Q q 0 0 0 rg BT 371.15 349.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 411.97 349.25 Td (useful ) Tj ET Q q 0 0 0 rg BT 438.91 349.25 Td (life ) Tj ET Q q 0 0 0 rg BT 454.74 349.25 Td (of ) Tj ET Q q 0 0 0 rg BT 465.57 349.25 Td (the ) Tj ET Q q 0 0 0 rg BT 480.28 349.25 Td (software. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 325.25 Td (Acquisitions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.25 Td (Businesses ) Tj ET Q q 0 0 0 rg BT 82.33 305.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 119.20 305.25 Td (are ) Tj ET Q q 0 0 0 rg BT 133.85 305.25 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 186.84 305.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 209.28 305.25 Td (obtaining ) Tj ET Q q 0 0 0 rg BT 249.50 305.25 Td (control. ) Tj ET Q q 0 0 0 rg BT 282.59 305.25 Td (The ) Tj ET Q q 0 0 0 rg BT 300.58 305.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 316.90 305.25 Td (value ) Tj ET Q q 0 0 0 rg BT 340.99 305.25 Td (of ) Tj ET Q q 0 0 0 rg BT 351.77 305.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 377.54 305.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 414.41 305.25 Td (and ) Tj ET Q q 0 0 0 rg BT 431.29 305.25 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 470.95 305.25 Td (assumed ) Tj ET Q q 0 0 0 rg BT 507.83 305.25 Td (are ) Tj ET Q q 0 0 0 rg BT 522.48 305.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 568.78 305.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.06 293.25 Td (date ) Tj ET Q q 0 0 0 rg BT 68.55 293.25 Td (of ) Tj ET Q q 0 0 0 rg BT 78.72 293.25 Td (acquisition. ) Tj ET Q q 0 0 0 rg BT 126.53 293.25 Td (Any ) Tj ET Q q 0 0 0 rg BT 145.59 293.25 Td (excess ) Tj ET Q q 0 0 0 rg BT 173.53 293.25 Td (of ) Tj ET Q q 0 0 0 rg BT 183.70 293.25 Td (the ) Tj ET Q q 0 0 0 rg BT 197.75 293.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 235.13 293.25 Td (price ) Tj ET Q q 0 0 0 rg BT 256.95 293.25 Td (over ) Tj ET Q q 0 0 0 rg BT 276.56 293.25 Td (the ) Tj ET Q q 0 0 0 rg BT 290.61 293.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 330.77 293.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 346.49 293.25 Td (values ) Tj ET Q q 0 0 0 rg BT 373.87 293.25 Td (of ) Tj ET Q q 0 0 0 rg BT 384.04 293.25 Td (the ) Tj ET Q q 0 0 0 rg BT 398.10 293.25 Td (net ) Tj ET Q q 0 0 0 rg BT 412.15 293.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 437.32 293.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 473.58 293.25 Td (is ) Tj ET Q q 0 0 0 rg BT 482.09 293.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 527.79 293.25 Td (as ) Tj ET Q q 0 0 0 rg BT 537.96 293.25 Td (goodwill. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.25 Td (Business ) Tj ET Q q 0 0 0 rg BT 74.02 281.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 120.36 281.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 142.82 281.25 Td (are ) Tj ET Q q 0 0 0 rg BT 157.48 281.25 Td (expensed ) Tj ET Q q 0 0 0 rg BT 197.15 281.25 Td (when ) Tj ET Q q 0 0 0 rg BT 221.26 281.25 Td (incurred. ) Tj ET Q q 0 0 0 rg BT 259.54 281.25 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 306.44 281.25 Td (consideration ) Tj ET Q q 0 0 0 rg BT 362.77 281.25 Td (from ) Tj ET Q q 0 0 0 rg BT 384.66 281.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 422.11 281.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 478.72 281.25 Td (regulatory) Tj ET Q q 0 0 0 rg BT 519.16 281.25 Td (, ) Tj ET Q q 0 0 0 rg BT 524.12 281.25 Td (approval ) Tj ET Q q 0 0 0 rg BT 561.56 281.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 83.86 269.25 Td (milestones ) Tj ET Q q 0 0 0 rg BT 128.96 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 145.73 269.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 193.59 269.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 230.35 269.25 Td (are ) Tj ET Q q 0 0 0 rg BT 244.88 269.25 Td (included ) Tj ET Q q 0 0 0 rg BT 281.64 269.25 Td (in ) Tj ET Q q 0 0 0 rg BT 291.74 269.25 Td (the ) Tj ET Q q 0 0 0 rg BT 306.29 269.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 344.15 269.25 Td (price ) Tj ET Q q 0 0 0 rg BT 366.46 269.25 Td (for ) Tj ET Q q 0 0 0 rg BT 380.45 269.25 Td (business ) Tj ET Q q 0 0 0 rg BT 416.66 269.25 Td (combinations ) Tj ET Q q 0 0 0 rg BT 472.87 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 489.64 269.25 Td (are ) Tj ET Q q 0 0 0 rg BT 504.17 269.25 Td (excluded ) Tj ET Q q 0 0 0 rg BT 542.59 269.25 Td (for ) Tj ET Q q 0 0 0 rg BT 556.57 269.25 Td (asset ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.25 Td (acquisitions. ) Tj ET Q q 0 0 0 rg BT 88.22 257.25 Td (Amounts ) Tj ET Q q 0 0 0 rg BT 127.39 257.25 Td (allocated ) Tj ET Q q 0 0 0 rg BT 165.98 257.25 Td (to ) Tj ET Q q 0 0 0 rg BT 176.26 257.25 Td (the ) Tj ET Q q 0 0 0 rg BT 190.98 257.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 210.13 257.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 271.51 257.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 320.12 257.25 Td (for ) Tj ET Q q 0 0 0 rg BT 334.28 257.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 356.21 257.25 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 406.49 257.25 Td (are ) Tj ET Q q 0 0 0 rg BT 421.20 257.25 Td (expensed ) Tj ET Q q 0 0 0 rg BT 460.90 257.25 Td (at ) Tj ET Q q 0 0 0 rg BT 470.62 257.25 Td (the ) Tj ET Q q 0 0 0 rg BT 485.34 257.25 Td (date ) Tj ET Q q 0 0 0 rg BT 504.49 257.25 Td (of ) Tj ET Q q 0 0 0 rg BT 515.32 257.25 Td (acquisition. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 233.25 Td (Goodwill, ) Tj ET Q q 0 0 0 rg BT 79.34 233.25 Td (Acquir) Tj ET Q q 0 0 0 rg BT 109.16 233.25 Td (ed In-Pr) Tj ET Q q 0 0 0 rg BT 144.81 233.25 Td (ocess Resear) Tj ET Q q 0 0 0 rg BT 198.22 233.25 Td (ch and Development and Other) Tj ET Q q 0 0 0 rg BT 331.93 233.25 Td ( Intangible ) Tj ET Q q 0 0 0 rg BT 380.28 233.25 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.30 213.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 70.93 213.25 Td (value ) Tj ET Q q 0 0 0 rg BT 95.35 213.25 Td (of ) Tj ET Q q 0 0 0 rg BT 106.43 213.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 143.61 213.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 186.36 213.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 212.44 213.25 Td (is ) Tj ET Q q 0 0 0 rg BT 221.87 213.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 259.61 213.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 307.35 213.25 Td (using ) Tj ET Q q 0 0 0 rg BT 331.77 213.25 Td (the ) Tj ET Q q 0 0 0 rg BT 346.75 213.25 Td (“income ) Tj ET Q q 0 0 0 rg BT 383.37 213.25 Td (method” ) Tj ET Q q 0 0 0 rg BT 420.56 213.25 Td (utilizing ) Tj ET Q q 0 0 0 rg BT 456.65 213.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 482.17 213.25 Td (3 ) Tj ET Q q 0 0 0 rg BT 489.92 213.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 506.55 213.25 Td (value ) Tj ET Q q 0 0 0 rg BT 530.96 213.25 Td (inputs. ) Tj ET Q q 0 0 0 rg BT 560.47 213.25 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.25 Td (market ) Tj ET Q q 0 0 0 rg BT 66.32 201.25 Td (participant ) Tj ET Q q 0 0 0 rg BT 111.64 201.25 Td (valuations ) Tj ET Q q 0 0 0 rg BT 155.30 201.25 Td (assume ) Tj ET Q q 0 0 0 rg BT 187.29 201.25 Td (a ) Tj ET Q q 0 0 0 rg BT 194.29 201.25 Td (global ) Tj ET Q q 0 0 0 rg BT 221.84 201.25 Td (view ) Tj ET Q q 0 0 0 rg BT 243.84 201.25 Td (considering ) Tj ET Q q 0 0 0 rg BT 293.05 201.25 Td (all ) Tj ET Q q 0 0 0 rg BT 305.61 201.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 343.15 201.25 Td (jurisdictions ) Tj ET Q q 0 0 0 rg BT 395.15 201.25 Td (and ) Tj ET Q q 0 0 0 rg BT 412.15 201.25 Td (indications ) Tj ET Q q 0 0 0 rg BT 458.59 201.25 Td (based ) Tj ET Q q 0 0 0 rg BT 483.92 201.25 Td (on ) Tj ET Q q 0 0 0 rg BT 496.47 201.25 Td (discounted ) Tj ET Q q 0 0 0 rg BT 542.36 201.25 Td (after) Tj ET Q q 0 0 0 rg BT 560.47 201.25 Td (-tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 56.27 189.25 Td (flow ) Tj ET Q q 0 0 0 rg BT 77.10 189.25 Td (projections, ) Tj ET Q q 0 0 0 rg BT 126.53 189.25 Td (risk ) Tj ET Q q 0 0 0 rg BT 144.03 189.25 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 179.86 189.25 Td (for ) Tj ET Q q 0 0 0 rg BT 194.02 189.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 234.84 189.25 Td (probability ) Tj ET Q q 0 0 0 rg BT 281.22 189.25 Td (of ) Tj ET Q q 0 0 0 rg BT 292.05 189.25 Td (technical ) Tj ET Q q 0 0 0 rg BT 330.64 189.25 Td (and ) Tj ET Q q 0 0 0 rg BT 347.58 189.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 391.17 189.25 Td (success ) Tj ET Q q 0 0 0 rg BT 423.66 189.25 Td (\(for ) Tj ET Q q 0 0 0 rg BT 441.15 189.25 Td (IPRD\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 165.25 Td (Finite-lived ) Tj ET Q q 0 0 0 rg BT 86.60 165.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 130.53 165.25 Td (assets, ) Tj ET Q q 0 0 0 rg BT 160.30 165.25 Td (including ) Tj ET Q q 0 0 0 rg BT 202.01 165.25 Td (licenses, ) Tj ET Q q 0 0 0 rg BT 240.11 165.25 Td (developed ) Tj ET Q q 0 0 0 rg BT 285.14 165.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 333.51 165.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 360.23 165.25 Td (and ) Tj ET Q q 0 0 0 rg BT 378.61 165.25 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 405.33 165.25 Td (projects ) Tj ET Q q 0 0 0 rg BT 440.93 165.25 Td (that ) Tj ET Q q 0 0 0 rg BT 459.86 165.25 Td (reach ) Tj ET Q q 0 0 0 rg BT 485.45 165.25 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 563.79 165.25 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 153.25 Td (amortized ) Tj ET Q q 0 0 0 rg BT 78.20 153.25 Td (on ) Tj ET Q q 0 0 0 rg BT 90.41 153.25 Td (a ) Tj ET Q q 0 0 0 rg BT 97.07 153.25 Td (straight-line ) Tj ET Q q 0 0 0 rg BT 147.61 153.25 Td (basis ) Tj ET Q q 0 0 0 rg BT 169.82 153.25 Td (over ) Tj ET Q q 0 0 0 rg BT 189.81 153.25 Td (their ) Tj ET Q q 0 0 0 rg BT 210.35 153.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 250.89 153.25 Td (useful ) Tj ET Q q 0 0 0 rg BT 277.54 153.25 Td (life. ) Tj ET Q q 0 0 0 rg BT 295.58 153.25 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 337.79 153.25 Td (useful ) Tj ET Q q 0 0 0 rg BT 364.45 153.25 Td (lives ) Tj ET Q q 0 0 0 rg BT 385.55 153.25 Td (are ) Tj ET Q q 0 0 0 rg BT 399.97 153.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 447.17 153.25 Td (considering ) Tj ET Q q 0 0 0 rg BT 496.04 153.25 Td (the ) Tj ET Q q 0 0 0 rg BT 510.48 153.25 Td (period ) Tj ET Q q 0 0 0 rg BT 538.24 153.25 Td (the ) Tj ET Q q 0 0 0 rg BT 552.67 153.25 Td (assets ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 141.25 Td (are ) Tj ET Q q 0 0 0 rg BT 50.71 141.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 88.74 141.25 Td (to ) Tj ET Q q 0 0 0 rg BT 99.02 141.25 Td (contribute ) Tj ET Q q 0 0 0 rg BT 142.06 141.25 Td (to ) Tj ET Q q 0 0 0 rg BT 152.34 141.25 Td (future ) Tj ET Q q 0 0 0 rg BT 178.71 141.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 198.98 141.25 Td (flows.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 117.25 Td (Goodwill ) Tj ET Q q 0 0 0 rg BT 76.26 117.25 Td (is ) Tj ET Q q 0 0 0 rg BT 85.40 117.25 Td (tested ) Tj ET Q q 0 0 0 rg BT 111.20 117.25 Td (at ) Tj ET Q q 0 0 0 rg BT 120.90 117.25 Td (least ) Tj ET Q q 0 0 0 rg BT 141.70 117.25 Td (annually ) Tj ET Q q 0 0 0 rg BT 178.61 117.25 Td (for ) Tj ET Q q 0 0 0 rg BT 192.75 117.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 241.32 117.25 Td (by ) Tj ET Q q 0 0 0 rg BT 253.80 117.25 Td (assessing ) Tj ET Q q 0 0 0 rg BT 293.50 117.25 Td (qualitative ) Tj ET Q q 0 0 0 rg BT 338.18 117.25 Td (factors ) Tj ET Q q 0 0 0 rg BT 367.87 117.25 Td (or ) Tj ET Q q 0 0 0 rg BT 378.68 117.25 Td (performing ) Tj ET Q q 0 0 0 rg BT 426.14 117.25 Td (a ) Tj ET Q q 0 0 0 rg BT 433.05 117.25 Td (quantitative ) Tj ET Q q 0 0 0 rg BT 482.74 117.25 Td (analysis ) Tj ET Q q 0 0 0 rg BT 517.43 117.25 Td (in ) Tj ET Q q 0 0 0 rg BT 527.69 117.25 Td (determining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 105.25 Td (whether ) Tj ET Q q 0 0 0 rg BT 69.94 105.25 Td (it ) Tj ET Q q 0 0 0 rg BT 77.23 105.25 Td (is ) Tj ET Q q 0 0 0 rg BT 85.64 105.25 Td (more ) Tj ET Q q 0 0 0 rg BT 107.92 105.25 Td (likely ) Tj ET Q q 0 0 0 rg BT 132.43 105.25 Td (than ) Tj ET Q q 0 0 0 rg BT 151.38 105.25 Td (not ) Tj ET Q q 0 0 0 rg BT 165.89 105.25 Td (that ) Tj ET Q q 0 0 0 rg BT 182.62 105.25 Td (the ) Tj ET Q q 0 0 0 rg BT 196.57 105.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 212.19 105.25 Td (value ) Tj ET Q q 0 0 0 rg BT 235.58 105.25 Td (of ) Tj ET Q q 0 0 0 rg BT 245.64 105.25 Td (net ) Tj ET Q q 0 0 0 rg BT 259.59 105.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 284.66 105.25 Td (are ) Tj ET Q q 0 0 0 rg BT 298.60 105.25 Td (below ) Tj ET Q q 0 0 0 rg BT 324.77 105.25 Td (their ) Tj ET Q q 0 0 0 rg BT 344.83 105.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 379.88 105.25 Td (amounts. ) Tj ET Q q 0 0 0 rg BT 418.01 105.25 Td (Examples ) Tj ET Q q 0 0 0 rg BT 459.17 105.25 Td (of ) Tj ET Q q 0 0 0 rg BT 469.24 105.25 Td (qualitative ) Tj ET Q q 0 0 0 rg BT 513.18 105.25 Td (factors ) Tj ET Q q 0 0 0 rg BT 542.12 105.25 Td (assessed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 93.25 Td (include ) Tj ET Q q 0 0 0 rg BT 68.63 93.25 Td (our ) Tj ET Q q 0 0 0 rg BT 85.16 93.25 Td (share ) Tj ET Q q 0 0 0 rg BT 109.46 93.25 Td (price, ) Tj ET Q q 0 0 0 rg BT 135.15 93.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 173.33 93.25 Td (performance ) Tj ET Q q 0 0 0 rg BT 227.05 93.25 Td (compared ) Tj ET Q q 0 0 0 rg BT 269.67 93.25 Td (to ) Tj ET Q q 0 0 0 rg BT 280.65 93.25 Td (budgets, ) Tj ET Q q 0 0 0 rg BT 317.46 93.25 Td (long-term ) Tj ET Q q 0 0 0 rg BT 360.09 93.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 398.27 93.25 Td (plans, ) Tj ET Q q 0 0 0 rg BT 425.08 93.25 Td (macroeconomic, ) Tj ET Q q 0 0 0 rg BT 494.64 93.25 Td (industry ) Tj ET Q q 0 0 0 rg BT 530.62 93.25 Td (and ) Tj ET Q q 0 0 0 rg BT 548.25 93.25 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 81.25 Td (conditions ) Tj ET Q q 0 0 0 rg BT 79.97 81.25 Td (as ) Tj ET Q q 0 0 0 rg BT 90.61 81.25 Td (well ) Tj ET Q q 0 0 0 rg BT 110.13 81.25 Td (as ) Tj ET Q q 0 0 0 rg BT 120.77 81.25 Td (the ) Tj ET Q q 0 0 0 rg BT 135.29 81.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 180.37 81.25 Td (excess ) Tj ET Q q 0 0 0 rg BT 208.77 81.25 Td (of ) Tj ET Q q 0 0 0 rg BT 219.41 81.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 235.59 81.25 Td (value ) Tj ET Q q 0 0 0 rg BT 259.55 81.25 Td (over ) Tj ET Q q 0 0 0 rg BT 279.63 81.25 Td (the ) Tj ET Q q 0 0 0 rg BT 294.15 81.25 Td (carrying ) Tj ET Q q 0 0 0 rg BT 329.77 81.25 Td (value ) Tj ET Q q 0 0 0 rg BT 353.74 81.25 Td (of ) Tj ET Q q 0 0 0 rg BT 364.37 81.25 Td (net ) Tj ET Q q 0 0 0 rg BT 378.89 81.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 404.53 81.25 Td (from ) Tj ET Q q 0 0 0 rg BT 426.28 81.25 Td (the ) Tj ET Q q 0 0 0 rg BT 440.80 81.25 Td (annual ) Tj ET Q q 0 0 0 rg BT 469.76 81.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 518.16 81.25 Td (test ) Tj ET Q q 0 0 0 rg BT 534.36 81.25 Td (performed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 69.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 69.25 Td (a ) Tj ET Q q 0 0 0 rg BT 53.22 69.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 75.16 69.25 Td (year) Tj ET Q q 0 0 0 rg BT 91.81 69.25 Td (. ) Tj ET Q q 0 0 0 rg BT 96.81 69.25 Td (Each ) Tj ET Q q 0 0 0 rg BT 119.30 69.25 Td (relevant ) Tj ET Q q 0 0 0 rg BT 154.00 69.25 Td (factor ) Tj ET Q q 0 0 0 rg BT 179.81 69.25 Td (is ) Tj ET Q q 0 0 0 rg BT 188.98 69.25 Td (assessed ) Tj ET Q q 0 0 0 rg BT 225.37 69.25 Td (both ) Tj ET Q q 0 0 0 rg BT 245.64 69.25 Td (individually ) Tj ET Q q 0 0 0 rg BT 296.47 69.25 Td (and ) Tj ET Q q 0 0 0 rg BT 313.41 69.25 Td (in ) Tj ET Q q 0 0 0 rg BT 323.69 69.25 Td (the ) Tj ET Q q 0 0 0 rg BT 338.41 69.25 Td (aggregate.) Tj ET Q endstream endobj 125 0 obj <> endobj 126 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (62) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 61.83 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 71.55 749.10 Td (tested ) Tj ET Q q 0 0 0 rg BT 97.93 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 112.64 749.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 161.79 749.10 Td (on ) Tj ET Q q 0 0 0 rg BT 174.84 749.10 Td (an ) Tj ET Q q 0 0 0 rg BT 187.33 749.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 217.04 749.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 240.09 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 257.58 749.10 Td (more ) Tj ET Q q 0 0 0 rg BT 281.17 749.10 Td (frequently ) Tj ET Q q 0 0 0 rg BT 325.32 749.10 Td (if ) Tj ET Q q 0 0 0 rg BT 334.48 749.10 Td (events ) Tj ET Q q 0 0 0 rg BT 363.08 749.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 388.33 749.10 Td (or ) Tj ET Q q 0 0 0 rg BT 399.71 749.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 459.41 749.10 Td (change ) Tj ET Q q 0 0 0 rg BT 490.77 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 508.82 749.10 Td (would ) Tj ET Q q 0 0 0 rg BT 536.87 749.10 Td (indicate ) Tj ET Q q 0 0 0 rg BT 571.57 749.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 72.93 737.10 Td (reduction ) Tj ET Q q 0 0 0 rg BT 112.63 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 122.34 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 136.50 737.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 152.31 737.10 Td (values ) Tj ET Q q 0 0 0 rg BT 179.80 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 190.07 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 204.22 737.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 229.49 737.10 Td (below ) Tj ET Q q 0 0 0 rg BT 255.86 737.10 Td (their ) Tj ET Q q 0 0 0 rg BT 276.13 737.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 311.38 737.10 Td (value. ) Tj ET Q q 0 0 0 rg BT 337.47 737.10 Td (Impairment ) Tj ET Q q 0 0 0 rg BT 386.06 737.10 Td (char) Tj ET Q q 0 0 0 rg BT 403.09 737.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 418.35 737.10 Td (are ) Tj ET Q q 0 0 0 rg BT 432.50 737.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 478.30 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 488.01 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 502.17 737.10 Td (extent ) Tj ET Q q 0 0 0 rg BT 528.54 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 542.69 737.10 Td (carrying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (value ) Tj ET Q q 0 0 0 rg BT 60.16 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 70.99 725.10 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 96.27 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 105.44 725.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 152.92 725.10 Td (to ) Tj ET Q q 0 0 0 rg BT 163.20 725.10 Td (exceed ) Tj ET Q q 0 0 0 rg BT 193.45 725.10 Td (its ) Tj ET Q q 0 0 0 rg BT 205.40 725.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 221.78 725.10 Td (value.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (Finite-lived ) Tj ET Q q 0 0 0 rg BT 85.11 701.10 Td (intangible ) Tj ET Q q 0 0 0 rg BT 127.56 701.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 153.34 701.10 Td (are ) Tj ET Q q 0 0 0 rg BT 168.00 701.10 Td (tested ) Tj ET Q q 0 0 0 rg BT 193.78 701.10 Td (for ) Tj ET Q q 0 0 0 rg BT 207.89 701.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 256.45 701.10 Td (when ) Tj ET Q q 0 0 0 rg BT 280.56 701.10 Td (facts ) Tj ET Q q 0 0 0 rg BT 301.89 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 312.67 701.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 371.77 701.10 Td (suggest ) Tj ET Q q 0 0 0 rg BT 404.22 701.10 Td (that ) Tj ET Q q 0 0 0 rg BT 421.67 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 436.34 701.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 472.11 701.10 Td (value ) Tj ET Q q 0 0 0 rg BT 496.22 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 507.00 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 521.67 701.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 543.57 701.10 Td (may ) Tj ET Q q 0 0 0 rg BT 563.24 701.10 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (be ) Tj ET Q q 0 0 0 rg BT 48.31 689.10 Td (recoverable. ) Tj ET Q q 0 0 0 rg BT 100.32 689.10 Td (If ) Tj ET Q q 0 0 0 rg BT 109.86 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 124.95 689.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 161.14 689.10 Td (value ) Tj ET Q q 0 0 0 rg BT 185.67 689.10 Td (exceeds ) Tj ET Q q 0 0 0 rg BT 220.19 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 235.29 689.10 Td (projected ) Tj ET Q q 0 0 0 rg BT 275.37 689.10 Td (undiscounted ) Tj ET Q q 0 0 0 rg BT 331.57 689.10 Td (pretax ) Tj ET Q q 0 0 0 rg BT 359.43 689.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 380.07 689.10 Td (flows ) Tj ET Q q 0 0 0 rg BT 405.17 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 416.38 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 431.47 689.10 Td (intangible ) Tj ET Q q 0 0 0 rg BT 474.33 689.10 Td (asset, ) Tj ET Q q 0 0 0 rg BT 499.15 689.10 Td (an ) Tj ET Q q 0 0 0 rg BT 511.46 689.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 560.44 689.10 Td (loss ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (equal ) Tj ET Q q 0 0 0 rg BT 60.16 677.10 Td (to ) Tj ET Q q 0 0 0 rg BT 70.43 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 85.15 677.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 113.75 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 124.58 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 139.30 677.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 175.11 677.10 Td (value ) Tj ET Q q 0 0 0 rg BT 199.27 677.10 Td (over ) Tj ET Q q 0 0 0 rg BT 219.54 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 234.25 677.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 275.07 677.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 291.45 677.10 Td (value ) Tj ET Q q 0 0 0 rg BT 315.60 677.10 Td (\(discounted ) Tj ET Q q 0 0 0 rg BT 364.76 677.10 Td (after) Tj ET Q q 0 0 0 rg BT 382.88 677.10 Td (-tax ) Tj ET Q q 0 0 0 rg BT 400.92 677.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 421.19 677.10 Td (flows\) ) Tj ET Q q 0 0 0 rg BT 449.24 677.10 Td (is ) Tj ET Q q 0 0 0 rg BT 458.41 677.10 Td (recognized.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (Restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 633.10 Td (Restructuring ) Tj ET Q q 0 0 0 rg BT 93.16 633.10 Td (char) Tj ET Q q 0 0 0 rg BT 110.18 633.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 126.24 633.10 Td (are ) Tj ET Q q 0 0 0 rg BT 141.17 633.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 187.76 633.10 Td (as ) Tj ET Q q 0 0 0 rg BT 198.81 633.10 Td (a ) Tj ET Q q 0 0 0 rg BT 205.98 633.10 Td (result ) Tj ET Q q 0 0 0 rg BT 230.92 633.10 Td (of ) Tj ET Q q 0 0 0 rg BT 241.97 633.10 Td (actions ) Tj ET Q q 0 0 0 rg BT 273.02 633.10 Td (to ) Tj ET Q q 0 0 0 rg BT 283.52 633.10 Td (streamline ) Tj ET Q q 0 0 0 rg BT 327.90 633.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 372.28 633.10 Td (and ) Tj ET Q q 0 0 0 rg BT 389.44 633.10 Td (reduce ) Tj ET Q q 0 0 0 rg BT 418.81 633.10 Td (the ) Tj ET Q q 0 0 0 rg BT 433.75 633.10 Td (number ) Tj ET Q q 0 0 0 rg BT 467.03 633.10 Td (of ) Tj ET Q q 0 0 0 rg BT 478.08 633.10 Td (facilities. ) Tj ET Q q 0 0 0 rg BT 517.73 633.10 Td (Estimating ) Tj ET Q q 0 0 0 rg BT 563.79 633.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 65.22 621.10 Td (of ) Tj ET Q q 0 0 0 rg BT 75.56 621.10 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 128.66 621.10 Td (plans, ) Tj ET Q q 0 0 0 rg BT 154.28 621.10 Td (including ) Tj ET Q q 0 0 0 rg BT 194.06 621.10 Td (future ) Tj ET Q q 0 0 0 rg BT 219.94 621.10 Td (termination ) Tj ET Q q 0 0 0 rg BT 268.05 621.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 301.71 621.10 Td (and ) Tj ET Q q 0 0 0 rg BT 318.16 621.10 Td (other ) Tj ET Q q 0 0 0 rg BT 340.72 621.10 Td (exit ) Tj ET Q q 0 0 0 rg BT 357.72 621.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 379.73 621.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 413.94 621.10 Td (judgment. ) Tj ET Q q 0 0 0 rg BT 455.78 621.10 Td (Actual ) Tj ET Q q 0 0 0 rg BT 484.45 621.10 Td (results ) Tj ET Q q 0 0 0 rg BT 512.56 621.10 Td (could ) Tj ET Q q 0 0 0 rg BT 536.79 621.10 Td (vary ) Tj ET Q q 0 0 0 rg BT 556.56 621.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 609.10 Td (these ) Tj ET Q q 0 0 0 rg BT 59.05 609.10 Td (estimates.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 585.10 Td (Contingencies) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 565.10 Td (Loss ) Tj ET Q q 0 0 0 rg BT 58.01 565.10 Td (contingencies ) Tj ET Q q 0 0 0 rg BT 116.12 565.10 Td (from ) Tj ET Q q 0 0 0 rg BT 138.68 565.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 161.23 565.10 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 212.67 565.10 Td (and ) Tj ET Q q 0 0 0 rg BT 230.23 565.10 Td (claims ) Tj ET Q q 0 0 0 rg BT 259.45 565.10 Td (may ) Tj ET Q q 0 0 0 rg BT 279.79 565.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 305.12 565.10 Td (from ) Tj ET Q q 0 0 0 rg BT 327.68 565.10 Td (government ) Tj ET Q q 0 0 0 rg BT 378.56 565.10 Td (investigations, ) Tj ET Q q 0 0 0 rg BT 439.74 565.10 Td (shareholder ) Tj ET Q q 0 0 0 rg BT 489.51 565.10 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 527.91 565.10 Td (product ) Tj ET Q q 0 0 0 rg BT 561.57 565.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 553.10 Td (environmental ) Tj ET Q q 0 0 0 rg BT 97.01 553.10 Td (liability) Tj ET Q q 0 0 0 rg BT 127.47 553.10 Td (, ) Tj ET Q q 0 0 0 rg BT 133.23 553.10 Td (contractual ) Tj ET Q q 0 0 0 rg BT 180.90 553.10 Td (claims, ) Tj ET Q q 0 0 0 rg BT 212.76 553.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 228.23 553.10 Td (and ) Tj ET Q q 0 0 0 rg BT 245.92 553.10 Td (other ) Tj ET Q q 0 0 0 rg BT 269.72 553.10 Td (matters. ) Tj ET Q q 0 0 0 rg BT 304.19 553.10 Td (Accruals ) Tj ET Q q 0 0 0 rg BT 342.98 553.10 Td (are ) Tj ET Q q 0 0 0 rg BT 358.45 553.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 405.56 553.10 Td (when ) Tj ET Q q 0 0 0 rg BT 430.48 553.10 Td (it ) Tj ET Q q 0 0 0 rg BT 439.29 553.10 Td (is ) Tj ET Q q 0 0 0 rg BT 449.21 553.10 Td (probable ) Tj ET Q q 0 0 0 rg BT 487.45 553.10 Td (that ) Tj ET Q q 0 0 0 rg BT 505.70 553.10 Td (a ) Tj ET Q q 0 0 0 rg BT 513.39 553.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 547.76 553.10 Td (will ) Tj ET Q q 0 0 0 rg BT 566.57 553.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 541.10 Td (incurred ) Tj ET Q q 0 0 0 rg BT 70.91 541.10 Td (and ) Tj ET Q q 0 0 0 rg BT 86.95 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 100.77 541.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 132.36 541.10 Td (of ) Tj ET Q q 0 0 0 rg BT 142.29 541.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 159.45 541.10 Td (can ) Tj ET Q q 0 0 0 rg BT 174.93 541.10 Td (be ) Tj ET Q q 0 0 0 rg BT 185.97 541.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 230.88 541.10 Td (estimated. ) Tj ET Q q 0 0 0 rg BT 273.30 541.10 Td (Gain ) Tj ET Q q 0 0 0 rg BT 294.34 541.10 Td (contingencies ) Tj ET Q q 0 0 0 rg BT 350.92 541.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 393.62 541.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 437.43 541.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 474.57 541.10 Td (related ) Tj ET Q q 0 0 0 rg BT 503.37 541.10 Td (to ) Tj ET Q q 0 0 0 rg BT 512.75 541.10 Td (the ) Tj ET Q q 0 0 0 rg BT 526.56 541.10 Td (divestitures\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 529.10 Td (are ) Tj ET Q q 0 0 0 rg BT 50.71 529.10 Td (not ) Tj ET Q q 0 0 0 rg BT 65.99 529.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 112.35 529.10 Td (until ) Tj ET Q q 0 0 0 rg BT 133.18 529.10 Td (realized. ) Tj ET Q q 0 0 0 rg BT 169.82 529.10 Td (Legal ) Tj ET Q q 0 0 0 rg BT 195.09 529.10 Td (fees ) Tj ET Q q 0 0 0 rg BT 213.69 529.10 Td (are ) Tj ET Q q 0 0 0 rg BT 228.39 529.10 Td (expensed ) Tj ET Q q 0 0 0 rg BT 268.10 529.10 Td (as ) Tj ET Q q 0 0 0 rg BT 278.93 529.10 Td (incurred.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 505.10 Td (Advertising and Pr) Tj ET Q q 0 0 0 rg BT 117.49 505.10 Td (oduct Pr) Tj ET Q q 0 0 0 rg BT 154.25 505.10 Td (omotion Costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.10 Td (Advertising ) Tj ET Q q 0 0 0 rg BT 85.51 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 102.24 485.10 Td (product ) Tj ET Q q 0 0 0 rg BT 135.07 485.10 Td (promotion ) Tj ET Q q 0 0 0 rg BT 179.03 485.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 201.32 485.10 Td (are ) Tj ET Q q 0 0 0 rg BT 215.81 485.10 Td (included ) Tj ET Q q 0 0 0 rg BT 252.54 485.10 Td (in ) Tj ET Q q 0 0 0 rg BT 262.61 485.10 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 307.94 485.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 336.89 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 353.62 485.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 413.12 485.10 Td (expenses ) Tj ET Q q 0 0 0 rg BT 451.51 485.10 Td (and ) Tj ET Q q 0 0 0 rg BT 468.24 485.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.96 485.10 Td ($740 ) Tj ET Q q 0 0 0 rg BT 512.25 485.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 541.14 485.10 Td ( ) Tj ET Q q 0 0 0 rg BT 543.43 485.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.50 485.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.50 485.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.10 Td ($789 ) Tj ET Q q 0 0 0 rg BT 58.50 473.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.39 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 89.89 473.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.17 473.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 120.17 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 122.67 473.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.61 473.10 Td ($825 ) Tj ET Q q 0 0 0 rg BT 162.11 473.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 191.00 473.10 Td ( ) Tj ET Q q 0 0 0 rg BT 193.50 473.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 203.78 473.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.78 473.10 Td (. ) Tj ET Q q 0 0 0 rg BT 228.23 473.10 Td (Advertising ) Tj ET Q q 0 0 0 rg BT 277.94 473.10 Td (and ) Tj ET Q q 0 0 0 rg BT 294.88 473.10 Td (product ) Tj ET Q q 0 0 0 rg BT 327.93 473.10 Td (promotion ) Tj ET Q q 0 0 0 rg BT 372.09 473.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 394.59 473.10 Td (are ) Tj ET Q q 0 0 0 rg BT 409.30 473.10 Td (expensed ) Tj ET Q q 0 0 0 rg BT 449.01 473.10 Td (as ) Tj ET Q q 0 0 0 rg BT 459.84 473.10 Td (incurred. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (For) Tj ET Q q 0 0 0 rg BT 51.37 449.10 Td (eign Curr) Tj ET Q q 0 0 0 rg BT 93.12 449.10 Td (ency ) Tj ET Q q 0 0 0 rg BT 114.88 449.10 Td (T) Tj ET Q q 0 0 0 rg BT 120.81 449.10 Td (ranslation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 429.10 Td (Foreign ) Tj ET Q q 0 0 0 rg BT 70.60 429.10 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 115.21 429.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 152.58 429.10 Td (are ) Tj ET Q q 0 0 0 rg BT 168.29 429.10 Td (translated ) Tj ET Q q 0 0 0 rg BT 210.65 429.10 Td (into ) Tj ET Q q 0 0 0 rg BT 229.71 429.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 250.99 429.10 Td (dollars ) Tj ET Q q 0 0 0 rg BT 281.70 429.10 Td (using ) Tj ET Q q 0 0 0 rg BT 306.86 429.10 Td (average ) Tj ET Q q 0 0 0 rg BT 341.44 429.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 382.69 429.10 Td (rates. ) Tj ET Q q 0 0 0 rg BT 407.31 429.10 Td (The ) Tj ET Q q 0 0 0 rg BT 426.36 429.10 Td (net ) Tj ET Q q 0 0 0 rg BT 442.07 429.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 468.90 429.10 Td (of ) Tj ET Q q 0 0 0 rg BT 480.72 429.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 513.10 429.10 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 563.81 429.10 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 417.10 Td (translated ) Tj ET Q q 0 0 0 rg BT 76.26 417.10 Td (into ) Tj ET Q q 0 0 0 rg BT 93.20 417.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 112.36 417.10 Td (dollars ) Tj ET Q q 0 0 0 rg BT 140.97 417.10 Td (using ) Tj ET Q q 0 0 0 rg BT 164.02 417.10 Td (current ) Tj ET Q q 0 0 0 rg BT 193.72 417.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 232.86 417.10 Td (rates. ) Tj ET Q q 0 0 0 rg BT 255.52 417.10 Td (The ) Tj ET Q q 0 0 0 rg BT 272.45 417.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 291.62 417.10 Td (dollar ) Tj ET Q q 0 0 0 rg BT 316.33 417.10 Td (ef) Tj ET Q q 0 0 0 rg BT 323.92 417.10 Td (fects ) Tj ET Q q 0 0 0 rg BT 344.18 417.10 Td (that ) Tj ET Q q 0 0 0 rg BT 360.56 417.10 Td (arise ) Tj ET Q q 0 0 0 rg BT 380.82 417.10 Td (from ) Tj ET Q q 0 0 0 rg BT 401.64 417.10 Td (translating ) Tj ET Q q 0 0 0 rg BT 445.24 417.10 Td (the ) Tj ET Q q 0 0 0 rg BT 458.84 417.10 Td (net ) Tj ET Q q 0 0 0 rg BT 472.44 417.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 497.15 417.10 Td (of ) Tj ET Q q 0 0 0 rg BT 506.87 417.10 Td (these ) Tj ET Q q 0 0 0 rg BT 528.80 417.10 Td (subsidiaries ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.10 Td (at ) Tj ET Q q 0 0 0 rg BT 45.72 405.10 Td (changing ) Tj ET Q q 0 0 0 rg BT 84.87 405.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 106.25 405.10 Td (are ) Tj ET Q q 0 0 0 rg BT 120.96 405.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 167.32 405.10 Td (in ) Tj ET Q q 0 0 0 rg BT 177.60 405.10 Td (OCI.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 381.10 Td (Resear) Tj ET Q q 0 0 0 rg BT 65.25 381.10 Td (ch and Development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 361.10 Td (Research ) Tj ET Q q 0 0 0 rg BT 75.98 361.10 Td (and ) Tj ET Q q 0 0 0 rg BT 93.74 361.10 Td (development ) Tj ET Q q 0 0 0 rg BT 148.72 361.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 172.05 361.10 Td (are ) Tj ET Q q 0 0 0 rg BT 187.59 361.10 Td (expensed ) Tj ET Q q 0 0 0 rg BT 228.13 361.10 Td (as ) Tj ET Q q 0 0 0 rg BT 239.79 361.10 Td (incurred. ) Tj ET Q q 0 0 0 rg BT 278.93 361.10 Td (Clinical ) Tj ET Q q 0 0 0 rg BT 313.92 361.10 Td (study ) Tj ET Q q 0 0 0 rg BT 338.92 361.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 362.25 361.10 Td (are ) Tj ET Q q 0 0 0 rg BT 377.79 361.10 Td (accrued ) Tj ET Q q 0 0 0 rg BT 412.21 361.10 Td (over ) Tj ET Q q 0 0 0 rg BT 433.30 361.10 Td (the ) Tj ET Q q 0 0 0 rg BT 448.85 361.10 Td (service ) Tj ET Q q 0 0 0 rg BT 480.50 361.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 513.27 361.10 Td (specified ) Tj ET Q q 0 0 0 rg BT 552.69 361.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.80 361.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 75.77 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 93.88 349.10 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 130.87 349.10 Td (as ) Tj ET Q q 0 0 0 rg BT 142.88 349.10 Td (necessary ) Tj ET Q q 0 0 0 rg BT 185.41 349.10 Td (based ) Tj ET Q q 0 0 0 rg BT 211.85 349.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 235.53 349.10 Td (an ) Tj ET Q q 0 0 0 rg BT 248.64 349.10 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 285.09 349.10 Td (review ) Tj ET Q q 0 0 0 rg BT 315.97 349.10 Td (of ) Tj ET Q q 0 0 0 rg BT 327.97 349.10 Td (the ) Tj ET Q q 0 0 0 rg BT 343.86 349.10 Td (level ) Tj ET Q q 0 0 0 rg BT 366.96 349.10 Td (of ) Tj ET Q q 0 0 0 rg BT 378.96 349.10 Td (ef) Tj ET Q q 0 0 0 rg BT 386.55 349.10 Td (fort ) Tj ET Q q 0 0 0 rg BT 404.66 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 422.77 349.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 446.44 349.10 Td (actually ) Tj ET Q q 0 0 0 rg BT 481.77 349.10 Td (incurred. ) Tj ET Q q 0 0 0 rg BT 521.25 349.10 Td (Research ) Tj ET Q q 0 0 0 rg BT 561.57 349.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 337.10 Td (development ) Tj ET Q q 0 0 0 rg BT 90.87 337.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 114.10 337.10 Td (are ) Tj ET Q q 0 0 0 rg BT 129.53 337.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 171.06 337.10 Td (net ) Tj ET Q q 0 0 0 rg BT 186.50 337.10 Td (of ) Tj ET Q q 0 0 0 rg BT 198.06 337.10 Td (reimbursements ) Tj ET Q q 0 0 0 rg BT 265.15 337.10 Td (from ) Tj ET Q q 0 0 0 rg BT 287.81 337.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 322.12 337.10 Td (partners. ) Tj ET Q q 0 0 0 rg BT 360.05 337.10 Td (Upfront ) Tj ET Q q 0 0 0 rg BT 394.94 337.10 Td (and ) Tj ET Q q 0 0 0 rg BT 412.60 337.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 458.03 337.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 500.14 337.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 541.68 337.10 Td (for ) Tj ET Q q 0 0 0 rg BT 556.57 337.10 Td (asset ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 85.93 325.10 Td (of ) Tj ET Q q 0 0 0 rg BT 96.42 325.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 157.45 325.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 205.71 325.10 Td (are ) Tj ET Q q 0 0 0 rg BT 220.07 325.10 Td (also ) Tj ET Q q 0 0 0 rg BT 238.34 325.10 Td (included ) Tj ET Q q 0 0 0 rg BT 274.93 325.10 Td (in ) Tj ET Q q 0 0 0 rg BT 284.86 325.10 Td (research ) Tj ET Q q 0 0 0 rg BT 320.32 325.10 Td (and ) Tj ET Q q 0 0 0 rg BT 336.92 325.10 Td (development ) Tj ET Q q 0 0 0 rg BT 390.72 325.10 Td (expenses ) Tj ET Q q 0 0 0 rg BT 428.98 325.10 Td (if ) Tj ET Q q 0 0 0 rg BT 437.24 325.10 Td (there ) Tj ET Q q 0 0 0 rg BT 459.38 325.10 Td (are ) Tj ET Q q 0 0 0 rg BT 473.75 325.10 Td (no ) Tj ET Q q 0 0 0 rg BT 485.90 325.10 Td (alternative ) Tj ET Q q 0 0 0 rg BT 530.26 325.10 Td (future ) Tj ET Q q 0 0 0 rg BT 556.29 325.10 Td (uses.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 301.10 Td (Cash ) Tj ET Q q 0 0 0 rg BT 60.17 301.10 Td (Flow) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (Payments ) Tj ET Q q 0 0 0 rg BT 77.48 281.10 Td (for ) Tj ET Q q 0 0 0 rg BT 91.73 281.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 130.42 281.10 Td (and ) Tj ET Q q 0 0 0 rg BT 147.45 281.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 169.47 281.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 219.84 281.10 Td (of ) Tj ET Q q 0 0 0 rg BT 230.76 281.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 292.22 281.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 340.92 281.10 Td (are ) Tj ET Q q 0 0 0 rg BT 355.72 281.10 Td (included ) Tj ET Q q 0 0 0 rg BT 392.74 281.10 Td (in ) Tj ET Q q 0 0 0 rg BT 403.11 281.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 443.46 281.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 482.15 281.10 Td (as ) Tj ET Q q 0 0 0 rg BT 493.07 281.10 Td (well ) Tj ET Q q 0 0 0 rg BT 512.87 281.10 Td (as ) Tj ET Q q 0 0 0 rg BT 523.79 281.10 Td (out-licensing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (proceeds. ) Tj ET Q q 0 0 0 rg BT 76.60 269.10 Td (Payments ) Tj ET Q q 0 0 0 rg BT 118.06 269.10 Td (for ) Tj ET Q q 0 0 0 rg BT 132.29 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 147.07 269.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 193.52 269.10 Td (of ) Tj ET Q q 0 0 0 rg BT 204.42 269.10 Td (an ) Tj ET Q q 0 0 0 rg BT 216.42 269.10 Td (ownership ) Tj ET Q q 0 0 0 rg BT 260.65 269.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 292.65 269.10 Td (in ) Tj ET Q q 0 0 0 rg BT 303.00 269.10 Td (a ) Tj ET Q q 0 0 0 rg BT 310.00 269.10 Td (legal ) Tj ET Q q 0 0 0 rg BT 332.00 269.10 Td (entity) Tj ET Q q 0 0 0 rg BT 354.13 269.10 Td (, ) Tj ET Q q 0 0 0 rg BT 359.20 269.10 Td (including ) Tj ET Q q 0 0 0 rg BT 399.54 269.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 449.88 269.10 Td (that ) Tj ET Q q 0 0 0 rg BT 467.44 269.10 Td (do ) Tj ET Q q 0 0 0 rg BT 480.01 269.10 Td (not ) Tj ET Q q 0 0 0 rg BT 495.35 269.10 Td (meet ) Tj ET Q q 0 0 0 rg BT 517.35 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 532.14 269.10 Td (accounting ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (definition ) Tj ET Q q 0 0 0 rg BT 77.85 257.10 Td (of ) Tj ET Q q 0 0 0 rg BT 89.16 257.10 Td (a ) Tj ET Q q 0 0 0 rg BT 96.57 257.10 Td (business ) Tj ET Q q 0 0 0 rg BT 133.43 257.10 Td (are ) Tj ET Q q 0 0 0 rg BT 148.61 257.10 Td (included ) Tj ET Q q 0 0 0 rg BT 186.02 257.10 Td (in ) Tj ET Q q 0 0 0 rg BT 196.77 257.10 Td (investing ) Tj ET Q q 0 0 0 rg BT 236.41 257.10 Td (activities, ) Tj ET Q q 0 0 0 rg BT 277.98 257.10 Td (as ) Tj ET Q q 0 0 0 rg BT 289.28 257.10 Td (well ) Tj ET Q q 0 0 0 rg BT 309.47 257.10 Td (as ) Tj ET Q q 0 0 0 rg BT 320.77 257.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 365.96 257.10 Td (proceeds, ) Tj ET Q q 0 0 0 rg BT 406.97 257.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 444.37 257.10 Td (and ) Tj ET Q q 0 0 0 rg BT 461.79 257.10 Td (other ) Tj ET Q q 0 0 0 rg BT 485.30 257.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 542.15 257.10 Td (received ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 83.27 245.10 Td (to ) Tj ET Q q 0 0 0 rg BT 93.88 245.10 Td (the ) Tj ET Q q 0 0 0 rg BT 108.92 245.10 Td (related ) Tj ET Q q 0 0 0 rg BT 138.95 245.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 157.33 245.10 Td (of ) Tj ET Q q 0 0 0 rg BT 168.49 245.10 Td (the ) Tj ET Q q 0 0 0 rg BT 183.54 245.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 205.80 245.10 Td (or ) Tj ET Q q 0 0 0 rg BT 216.96 245.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 256.19 245.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 281.78 245.10 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 332.39 245.10 Td (reflected ) Tj ET Q q 0 0 0 rg BT 370.19 245.10 Td (in ) Tj ET Q q 0 0 0 rg BT 380.79 245.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 421.39 245.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 460.32 245.10 Td (include ) Tj ET Q q 0 0 0 rg BT 492.58 245.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 537.62 245.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 561.56 245.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 62.16 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 78.87 233.10 Td (related ) Tj ET Q q 0 0 0 rg BT 108.34 233.10 Td (royalties, ) Tj ET Q q 0 0 0 rg BT 147.55 233.10 Td (research ) Tj ET Q q 0 0 0 rg BT 183.12 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 199.83 233.10 Td (development ) Tj ET Q q 0 0 0 rg BT 253.75 233.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 275.46 233.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 321.62 233.10 Td (char) Tj ET Q q 0 0 0 rg BT 338.64 233.10 Td (ges, ) Tj ET Q q 0 0 0 rg BT 356.74 233.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 380.12 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 396.83 233.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 422.99 233.10 Td (on ) Tj ET Q q 0 0 0 rg BT 435.26 233.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 454.75 233.10 Td (redemption ) Tj ET Q q 0 0 0 rg BT 502.56 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 519.27 233.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 553.75 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.80 233.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 52.38 221.10 Td (value ) Tj ET Q q 0 0 0 rg BT 76.53 221.10 Td (of ) Tj ET Q q 0 0 0 rg BT 87.36 221.10 Td (written ) Tj ET Q q 0 0 0 rg BT 118.19 221.10 Td (option ) Tj ET Q q 0 0 0 rg BT 146.24 221.10 Td (liabilities.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (Recently ) Tj ET Q q 0 0 0 rg BT 75.16 197.10 Td (Adopted ) Tj ET Q q 0 0 0 rg BT 113.78 197.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 165.17 197.10 Td (Standards) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 175.76699218750002 m 177.2841796875 175.76699218750002 l s q 0 0 0 rg BT 36.00 177.10 Td (Shar) Tj ET Q q 0 0 0 rg BT 54.52 177.10 Td (e-based ) Tj ET Q q 0 0 0 rg BT 88.12 177.10 Td (Payment ) Tj ET Q q 0 0 0 rg BT 125.60 177.10 Td (T) Tj ET Q q 0 0 0 rg BT 130.61 177.10 Td (ransactions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 162.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.12 162.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 115.46 162.10 Td (for ) Tj ET Q q 0 0 0 rg BT 129.37 162.10 Td (share-based ) Tj ET Q q 0 0 0 rg BT 178.81 162.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 215.49 162.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 265.50 162.10 Td (was ) Tj ET Q q 0 0 0 rg BT 283.29 162.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 317.19 162.10 Td (in ) Tj ET Q q 0 0 0 rg BT 327.22 162.10 Td (the ) Tj ET Q q 0 0 0 rg BT 341.68 162.10 Td (first ) Tj ET Q q 0 0 0 rg BT 360.03 162.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 390.59 162.10 Td (of ) Tj ET Q q 0 0 0 rg BT 401.17 162.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 425.91 162.10 Td (Net ) Tj ET Q q 0 0 0 rg BT 442.60 162.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 470.94 162.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 485.40 162.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 519.30 162.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 529.88 162.10 Td ($39 ) Tj ET Q q 0 0 0 rg BT 547.12 162.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 150.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.53 150.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 69.28 150.10 Td (were ) Tj ET Q q 0 0 0 rg BT 91.46 150.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 138.08 150.10 Td (prospectively ) Tj ET Q q 0 0 0 rg BT 194.70 150.10 Td (as ) Tj ET Q q 0 0 0 rg BT 205.78 150.10 Td (a ) Tj ET Q q 0 0 0 rg BT 212.97 150.10 Td (reduction ) Tj ET Q q 0 0 0 rg BT 253.49 150.10 Td (of ) Tj ET Q q 0 0 0 rg BT 264.57 150.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 279.54 150.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 314.49 150.10 Td (rather ) Tj ET Q q 0 0 0 rg BT 340.56 150.10 Td (than ) Tj ET Q q 0 0 0 rg BT 360.53 150.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 389.93 150.10 Td (in ) Tj ET Q q 0 0 0 rg BT 400.46 150.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 429.31 150.10 Td (of ) Tj ET Q q 0 0 0 rg BT 440.39 150.10 Td (par ) Tj ET Q q 0 0 0 rg BT 455.91 150.10 Td (value ) Tj ET Q q 0 0 0 rg BT 480.32 150.10 Td (of ) Tj ET Q q 0 0 0 rg BT 491.40 150.10 Td (stock. ) Tj ET Q q 0 0 0 rg BT 517.76 150.10 Td (Net ) Tj ET Q q 0 0 0 rg BT 534.95 150.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 563.80 150.10 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 138.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 69.70 138.10 Td (are ) Tj ET Q q 0 0 0 rg BT 83.95 138.10 Td (also ) Tj ET Q q 0 0 0 rg BT 102.11 138.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 142.47 138.10 Td (as ) Tj ET Q q 0 0 0 rg BT 152.85 138.10 Td (an ) Tj ET Q q 0 0 0 rg BT 164.33 138.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 204.14 138.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 223.95 138.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 244.33 138.10 Td (rather ) Tj ET Q q 0 0 0 rg BT 269.69 138.10 Td (than ) Tj ET Q q 0 0 0 rg BT 288.95 138.10 Td (a ) Tj ET Q q 0 0 0 rg BT 295.44 138.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 335.25 138.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 355.06 138.10 Td (flow) Tj ET Q q 0 0 0 rg BT 372.74 138.10 Td (, ) Tj ET Q q 0 0 0 rg BT 377.29 138.10 Td (and ) Tj ET Q q 0 0 0 rg BT 393.77 138.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 413.59 138.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 453.96 138.10 Td (to ) Tj ET Q q 0 0 0 rg BT 463.78 138.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 478.05 138.10 Td (authorities ) Tj ET Q q 0 0 0 rg BT 522.30 138.10 Td (in ) Tj ET Q q 0 0 0 rg BT 532.13 138.10 Td (connection ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 126.10 Td (with ) Tj ET Q q 0 0 0 rg BT 55.78 126.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 82.77 126.10 Td (withheld ) Tj ET Q q 0 0 0 rg BT 119.76 126.10 Td (for ) Tj ET Q q 0 0 0 rg BT 133.42 126.10 Td (statutory ) Tj ET Q q 0 0 0 rg BT 170.42 126.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 184.63 126.10 Td (withholding ) Tj ET Q q 0 0 0 rg BT 234.97 126.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 289.17 126.10 Td (are ) Tj ET Q q 0 0 0 rg BT 303.38 126.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 343.69 126.10 Td (as ) Tj ET Q q 0 0 0 rg BT 354.02 126.10 Td (a ) Tj ET Q q 0 0 0 rg BT 360.46 126.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 400.22 126.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 419.99 126.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 440.32 126.10 Td (rather ) Tj ET Q q 0 0 0 rg BT 465.63 126.10 Td (than ) Tj ET Q q 0 0 0 rg BT 484.85 126.10 Td (an ) Tj ET Q q 0 0 0 rg BT 496.29 126.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 536.05 126.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 555.82 126.10 Td (flow) Tj ET Q q 0 0 0 rg BT 573.50 126.10 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 114.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.60 114.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 89.86 114.10 Td (in ) Tj ET Q q 0 0 0 rg BT 100.69 114.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 121.51 114.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 142.89 114.10 Td (presentation ) Tj ET Q q 0 0 0 rg BT 194.81 114.10 Td (were ) Tj ET Q q 0 0 0 rg BT 217.29 114.10 Td (applied ) Tj ET Q q 0 0 0 rg BT 249.78 114.10 Td (retrospectively ) Tj ET Q q 0 0 0 rg BT 312.25 114.10 Td (and ) Tj ET Q q 0 0 0 rg BT 329.74 114.10 Td (increased ) Tj ET Q q 0 0 0 rg BT 370.55 114.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 411.36 114.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 432.18 114.10 Td (flows ) Tj ET Q q 0 0 0 rg BT 457.46 114.10 Td (and ) Tj ET Q q 0 0 0 rg BT 474.95 114.10 Td (decreased ) Tj ET Q q 0 0 0 rg BT 517.41 114.10 Td (financing ) Tj ET Q q 0 0 0 rg BT 558.23 114.10 Td (cash ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 102.10 Td (flows ) Tj ET Q q 0 0 0 rg BT 60.72 102.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 73.22 102.10 Td ($125 ) Tj ET Q q 0 0 0 rg BT 95.72 102.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 124.61 102.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 129.61 102.10 Td ($208 ) Tj ET Q q 0 0 0 rg BT 152.11 102.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 181.00 102.10 Td ( ) Tj ET Q q 0 0 0 rg BT 183.50 102.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 200.44 102.10 Td ($273 ) Tj ET Q q 0 0 0 rg BT 222.94 102.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.83 102.10 Td ( ) Tj ET Q q 0 0 0 rg BT 254.33 102.10 Td (in ) Tj ET Q q 0 0 0 rg BT 264.61 102.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 289.61 102.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 312.11 102.10 Td (and ) Tj ET Q q 0 0 0 rg BT 329.05 102.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 354.05 102.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 401.71 102.10 Td (.) Tj ET Q endstream endobj 127 0 obj <> endobj 128 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (63) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 359.681640625 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Income ) Tj ET Q q 0 0 0 rg BT 67.93 749.10 Td (T) Tj ET Q q 0 0 0 rg BT 72.57 749.10 Td (ax ) Tj ET Q q 0 0 0 rg BT 84.33 749.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 132.37 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 146.54 749.10 Td (Intra-entity ) Tj ET Q q 0 0 0 rg BT 194.58 749.10 Td (T) Tj ET Q q 0 0 0 rg BT 199.59 749.10 Td (ransfers ) Tj ET Q q 0 0 0 rg BT 234.88 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 244.97 749.10 Td (Assets ) Tj ET Q q 0 0 0 rg BT 272.47 749.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 298.30 749.10 Td (Than ) Tj ET Q q 0 0 0 rg BT 321.37 749.10 Td (Inventory) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 734.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 76.86 734.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 114.93 734.10 Td (on ) Tj ET Q q 0 0 0 rg BT 126.92 734.10 Td (income ) Tj ET Q q 0 0 0 rg BT 158.33 734.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 172.53 734.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 218.38 734.10 Td (for ) Tj ET Q q 0 0 0 rg BT 232.02 734.10 Td (intra-entity ) Tj ET Q q 0 0 0 rg BT 278.43 734.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 314.84 734.10 Td (of ) Tj ET Q q 0 0 0 rg BT 325.16 734.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 350.47 734.10 Td (other ) Tj ET Q q 0 0 0 rg BT 373.00 734.10 Td (than ) Tj ET Q q 0 0 0 rg BT 392.19 734.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 432.50 734.10 Td (was ) Tj ET Q q 0 0 0 rg BT 450.03 734.10 Td (early ) Tj ET Q q 0 0 0 rg BT 472.00 734.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 505.64 734.10 Td (in ) Tj ET Q q 0 0 0 rg BT 515.40 734.10 Td (the ) Tj ET Q q 0 0 0 rg BT 529.59 734.10 Td (first ) Tj ET Q q 0 0 0 rg BT 547.68 734.10 Td (quarter ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.79 722.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 69.25 722.10 Td (on ) Tj ET Q q 0 0 0 rg BT 81.72 722.10 Td (a ) Tj ET Q q 0 0 0 rg BT 88.62 722.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 127.18 722.10 Td (retrospective ) Tj ET Q q 0 0 0 rg BT 181.29 722.10 Td (approach. ) Tj ET Q q 0 0 0 rg BT 222.72 722.10 Td (The ) Tj ET Q q 0 0 0 rg BT 240.73 722.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 279.28 722.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 317.84 722.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 352.51 722.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 367.19 722.10 Td (consequences ) Tj ET Q q 0 0 0 rg BT 424.63 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 435.42 722.10 Td (these ) Tj ET Q q 0 0 0 rg BT 458.43 722.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 495.32 722.10 Td (be ) Tj ET Q q 0 0 0 rg BT 507.22 722.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 553.54 722.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 722.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 710.10 Td (period ) Tj ET Q q 0 0 0 rg BT 64.09 710.10 Td (the ) Tj ET Q q 0 0 0 rg BT 78.84 710.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 111.92 710.10 Td (takes ) Tj ET Q q 0 0 0 rg BT 135.01 710.10 Td (place. ) Tj ET Q q 0 0 0 rg BT 161.14 710.10 Td (Net ) Tj ET Q q 0 0 0 rg BT 178.12 710.10 Td (reductions ) Tj ET Q q 0 0 0 rg BT 222.32 710.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.64 710.10 Td (prepaid ) Tj ET Q q 0 0 0 rg BT 265.16 710.10 Td (and ) Tj ET Q q 0 0 0 rg BT 282.14 710.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 317.99 710.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 332.75 710.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 358.62 710.10 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 401.70 710.10 Td (to ) Tj ET Q q 0 0 0 rg BT 412.02 710.10 Td (pre-2017 ) Tj ET Q q 0 0 0 rg BT 450.66 710.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 483.74 710.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 520.71 710.10 Td (of ) Tj ET Q q 0 0 0 rg BT 531.58 710.10 Td (intellectual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 698.10 Td (property ) Tj ET Q q 0 0 0 rg BT 72.40 698.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 83.25 698.10 Td ($787 ) Tj ET Q q 0 0 0 rg BT 105.77 698.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 134.66 698.10 Td ( ) Tj ET Q q 0 0 0 rg BT 137.18 698.10 Td (were ) Tj ET Q q 0 0 0 rg BT 159.13 698.10 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 194.97 698.10 Td (through ) Tj ET Q q 0 0 0 rg BT 228.60 698.10 Td (retained ) Tj ET Q q 0 0 0 rg BT 263.32 698.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 299.72 698.10 Td (as ) Tj ET Q q 0 0 0 rg BT 310.57 698.10 Td (a ) Tj ET Q q 0 0 0 rg BT 317.52 698.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 364.47 698.10 Td (ef) Tj ET Q q 0 0 0 rg BT 372.06 698.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 389.56 698.10 Td (of ) Tj ET Q q 0 0 0 rg BT 400.41 698.10 Td (an ) Tj ET Q q 0 0 0 rg BT 412.37 698.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 458.76 698.10 Td (change ) Tj ET Q q 0 0 0 rg BT 489.60 698.10 Td (which ) Tj ET Q q 0 0 0 rg BT 516.56 698.10 Td (will ) Tj ET Q q 0 0 0 rg BT 534.63 698.10 Td (reduce ) Tj ET Q q 0 0 0 rg BT 563.80 698.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 686.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 65.59 686.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 80.74 686.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 115.88 686.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 128.81 686.10 Td ($86 ) Tj ET Q q 0 0 0 rg BT 146.74 686.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 175.63 686.10 Td ( ) Tj ET Q q 0 0 0 rg BT 178.56 686.10 Td (beginning ) Tj ET Q q 0 0 0 rg BT 221.49 686.10 Td (in ) Tj ET Q q 0 0 0 rg BT 232.20 686.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 257.63 686.10 Td (In ) Tj ET Q q 0 0 0 rg BT 268.90 686.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 307.10 686.10 Td (the ) Tj ET Q q 0 0 0 rg BT 322.25 686.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 337.40 686.10 Td (consequences ) Tj ET Q q 0 0 0 rg BT 395.31 686.10 Td (of ) Tj ET Q q 0 0 0 rg BT 406.57 686.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 449.49 686.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 482.97 686.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 520.33 686.10 Td (of ) Tj ET Q q 0 0 0 rg BT 531.59 686.10 Td (intellectual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 674.10 Td (property ) Tj ET Q q 0 0 0 rg BT 72.38 674.10 Td (that ) Tj ET Q q 0 0 0 rg BT 89.87 674.10 Td (may ) Tj ET Q q 0 0 0 rg BT 109.59 674.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 134.30 674.10 Td (in ) Tj ET Q q 0 0 0 rg BT 144.57 674.10 Td (the ) Tj ET Q q 0 0 0 rg BT 159.29 674.10 Td (future ) Tj ET Q q 0 0 0 rg BT 185.67 674.10 Td (will ) Tj ET Q q 0 0 0 rg BT 203.72 674.10 Td (be ) Tj ET Q q 0 0 0 rg BT 215.66 674.10 Td (included ) Tj ET Q q 0 0 0 rg BT 252.60 674.10 Td (in ) Tj ET Q q 0 0 0 rg BT 262.88 674.10 Td (income ) Tj ET Q q 0 0 0 rg BT 294.81 674.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 309.53 674.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 344.23 674.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 366.73 674.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 399.77 674.10 Td (and ) Tj ET Q q 0 0 0 rg BT 416.71 674.10 Td (not ) Tj ET Q q 0 0 0 rg BT 431.99 674.10 Td (amortized ) Tj ET Q q 0 0 0 rg BT 474.47 674.10 Td (in ) Tj ET Q q 0 0 0 rg BT 484.75 674.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 531.68 674.10 Td (periods.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 650.10 Td (Recently ) Tj ET Q q 0 0 0 rg BT 75.71 650.10 Td (Issued ) Tj ET Q q 0 0 0 rg BT 104.89 650.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 156.28 650.10 Td (Standards) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 628.7669921875 m 197.8408203125 628.7669921875 l s q 0 0 0 rg BT 36.00 630.10 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 72.36 630.10 Td (fr) Tj ET Q q 0 0 0 rg BT 78.66 630.10 Td (om ) Tj ET Q q 0 0 0 rg BT 93.38 630.10 Td (Contracts ) Tj ET Q q 0 0 0 rg BT 135.33 630.10 Td (with ) Tj ET Q q 0 0 0 rg BT 155.06 630.10 Td (Customers) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 615.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.14 615.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 115.49 615.10 Td (for ) Tj ET Q q 0 0 0 rg BT 129.41 615.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 163.31 615.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 211.11 615.10 Td (will ) Tj ET Q q 0 0 0 rg BT 228.92 615.10 Td (be ) Tj ET Q q 0 0 0 rg BT 240.62 615.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 274.54 615.10 Td (in ) Tj ET Q q 0 0 0 rg BT 284.57 615.10 Td (the ) Tj ET Q q 0 0 0 rg BT 299.05 615.10 Td (first ) Tj ET Q q 0 0 0 rg BT 317.41 615.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 347.99 615.10 Td (of ) Tj ET Q q 0 0 0 rg BT 358.58 615.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 380.83 615.10 Td (using ) Tj ET Q q 0 0 0 rg BT 404.76 615.10 Td (the ) Tj ET Q q 0 0 0 rg BT 419.24 615.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 457.60 615.10 Td (retrospective ) Tj ET Q q 0 0 0 rg BT 511.50 615.10 Td (method ) Tj ET Q q 0 0 0 rg BT 543.75 615.10 Td (with ) Tj ET Q q 0 0 0 rg BT 563.79 615.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 603.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 82.47 603.10 Td (ef) Tj ET Q q 0 0 0 rg BT 90.06 603.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 107.09 603.10 Td (of ) Tj ET Q q 0 0 0 rg BT 117.47 603.10 Td (the ) Tj ET Q q 0 0 0 rg BT 131.73 603.10 Td (change ) Tj ET Q q 0 0 0 rg BT 162.09 603.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 208.00 603.10 Td (in ) Tj ET Q q 0 0 0 rg BT 217.83 603.10 Td (retained ) Tj ET Q q 0 0 0 rg BT 252.07 603.10 Td (earnings. ) Tj ET Q q 0 0 0 rg BT 290.35 603.10 Td (The ) Tj ET Q q 0 0 0 rg BT 307.94 603.10 Td (new ) Tj ET Q q 0 0 0 rg BT 326.65 603.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 364.79 603.10 Td (referred ) Tj ET Q q 0 0 0 rg BT 398.47 603.10 Td (to ) Tj ET Q q 0 0 0 rg BT 408.29 603.10 Td (as ) Tj ET Q q 0 0 0 rg BT 418.22 603.10 Td (ASC ) Tj ET Q q 0 0 0 rg BT 439.72 603.10 Td (606 ) Tj ET Q q 0 0 0 rg BT 456.76 603.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 491.02 603.10 Td (an ) Tj ET Q q 0 0 0 rg BT 502.50 603.10 Td (entity ) Tj ET Q q 0 0 0 rg BT 527.32 603.10 Td (to ) Tj ET Q q 0 0 0 rg BT 537.14 603.10 Td (recognize ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 591.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.52 591.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 82.81 591.10 Td (of ) Tj ET Q q 0 0 0 rg BT 93.44 591.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 127.38 591.10 Td (to ) Tj ET Q q 0 0 0 rg BT 137.46 591.10 Td (which ) Tj ET Q q 0 0 0 rg BT 164.20 591.10 Td (it ) Tj ET Q q 0 0 0 rg BT 172.05 591.10 Td (expects ) Tj ET Q q 0 0 0 rg BT 204.34 591.10 Td (to ) Tj ET Q q 0 0 0 rg BT 214.41 591.10 Td (be ) Tj ET Q q 0 0 0 rg BT 226.15 591.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 258.44 591.10 Td (for ) Tj ET Q q 0 0 0 rg BT 272.40 591.10 Td (the ) Tj ET Q q 0 0 0 rg BT 286.92 591.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 319.75 591.10 Td (of ) Tj ET Q q 0 0 0 rg BT 330.38 591.10 Td (promised ) Tj ET Q q 0 0 0 rg BT 369.90 591.10 Td (goods ) Tj ET Q q 0 0 0 rg BT 396.09 591.10 Td (or ) Tj ET Q q 0 0 0 rg BT 406.71 591.10 Td (services ) Tj ET Q q 0 0 0 rg BT 441.22 591.10 Td (to ) Tj ET Q q 0 0 0 rg BT 451.30 591.10 Td (customers ) Tj ET Q q 0 0 0 rg BT 494.14 591.10 Td (and ) Tj ET Q q 0 0 0 rg BT 510.88 591.10 Td (replaces ) Tj ET Q q 0 0 0 rg BT 545.93 591.10 Td (most ) Tj ET Q q 0 0 0 rg BT 567.68 591.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 579.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.40 579.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 84.26 579.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 118.09 579.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 165.82 579.10 Td (standards ) Tj ET Q q 0 0 0 rg BT 205.78 579.10 Td (in ) Tj ET Q q 0 0 0 rg BT 215.74 579.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 235.71 579.10 Td (GAAP) Tj ET Q q 0 0 0 rg BT 261.83 579.10 Td (. ) Tj ET Q q 0 0 0 rg BT 266.03 579.10 Td (A) Tj ET Q q 0 0 0 rg BT 272.70 579.10 Td ( ) Tj ET Q q 0 0 0 rg BT 274.89 579.10 Td (five ) Tj ET Q q 0 0 0 rg BT 292.63 579.10 Td (step ) Tj ET Q q 0 0 0 rg BT 310.92 579.10 Td (model ) Tj ET Q q 0 0 0 rg BT 338.10 579.10 Td (will ) Tj ET Q q 0 0 0 rg BT 355.85 579.10 Td (be ) Tj ET Q q 0 0 0 rg BT 367.48 579.10 Td (utilized ) Tj ET Q q 0 0 0 rg BT 399.65 579.10 Td (to ) Tj ET Q q 0 0 0 rg BT 409.62 579.10 Td (achieve ) Tj ET Q q 0 0 0 rg BT 442.34 579.10 Td (the ) Tj ET Q q 0 0 0 rg BT 456.74 579.10 Td (core ) Tj ET Q q 0 0 0 rg BT 476.14 579.10 Td (principle; ) Tj ET Q q 0 0 0 rg BT 516.65 579.10 Td (\(1\) ) Tj ET Q q 0 0 0 rg BT 530.49 579.10 Td (identify ) Tj ET Q q 0 0 0 rg BT 563.78 579.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 567.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 75.67 567.10 Td (contract, ) Tj ET Q q 0 0 0 rg BT 113.39 567.10 Td (\(2\) ) Tj ET Q q 0 0 0 rg BT 128.07 567.10 Td (identify ) Tj ET Q q 0 0 0 rg BT 162.19 567.10 Td (the ) Tj ET Q q 0 0 0 rg BT 177.43 567.10 Td (contract’) Tj ET Q q 0 0 0 rg BT 212.41 567.10 Td (s ) Tj ET Q q 0 0 0 rg BT 219.32 567.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 272.86 567.10 Td (obligations, ) Tj ET Q q 0 0 0 rg BT 322.82 567.10 Td (\(3\) ) Tj ET Q q 0 0 0 rg BT 337.49 567.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 380.49 567.10 Td (the ) Tj ET Q q 0 0 0 rg BT 395.73 567.10 Td (transaction ) Tj ET Q q 0 0 0 rg BT 442.62 567.10 Td (price, ) Tj ET Q q 0 0 0 rg BT 468.12 567.10 Td (\(4\) ) Tj ET Q q 0 0 0 rg BT 482.80 567.10 Td (allocate ) Tj ET Q q 0 0 0 rg BT 516.90 567.10 Td (the ) Tj ET Q q 0 0 0 rg BT 532.14 567.10 Td (transaction ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 555.10 Td (price ) Tj ET Q q 0 0 0 rg BT 58.49 555.10 Td (to ) Tj ET Q q 0 0 0 rg BT 68.76 555.10 Td (the ) Tj ET Q q 0 0 0 rg BT 83.48 555.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 136.50 555.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 183.45 555.10 Td (and ) Tj ET Q q 0 0 0 rg BT 200.38 555.10 Td (\(5\) ) Tj ET Q q 0 0 0 rg BT 214.54 555.10 Td (recognize ) Tj ET Q q 0 0 0 rg BT 255.91 555.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 290.05 555.10 Td (when ) Tj ET Q q 0 0 0 rg BT 314.21 555.10 Td (or ) Tj ET Q q 0 0 0 rg BT 325.04 555.10 Td (as ) Tj ET Q q 0 0 0 rg BT 335.87 555.10 Td (a ) Tj ET Q q 0 0 0 rg BT 342.81 555.10 Td (performance ) Tj ET Q q 0 0 0 rg BT 395.83 555.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 438.89 555.10 Td (is ) Tj ET Q q 0 0 0 rg BT 448.06 555.10 Td (satisfied. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 531.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.30 531.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 95.96 531.10 Td (s ) Tj ET Q q 0 0 0 rg BT 102.60 531.10 Td (assessment ) Tj ET Q q 0 0 0 rg BT 149.79 531.10 Td (of ) Tj ET Q q 0 0 0 rg BT 160.87 531.10 Td (the ) Tj ET Q q 0 0 0 rg BT 175.84 531.10 Td (new ) Tj ET Q q 0 0 0 rg BT 195.25 531.10 Td (standard’) Tj ET Q q 0 0 0 rg BT 231.91 531.10 Td (s ) Tj ET Q q 0 0 0 rg BT 238.55 531.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 268.51 531.10 Td (is ) Tj ET Q q 0 0 0 rg BT 277.93 531.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 331.23 531.10 Td (complete. ) Tj ET Q q 0 0 0 rg BT 372.94 531.10 Td (The ) Tj ET Q q 0 0 0 rg BT 391.23 531.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 420.10 531.10 Td (of ) Tj ET Q q 0 0 0 rg BT 431.18 531.10 Td (recognizing ) Tj ET Q q 0 0 0 rg BT 481.13 531.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 515.53 531.10 Td (is ) Tj ET Q q 0 0 0 rg BT 524.95 531.10 Td (not ) Tj ET Q q 0 0 0 rg BT 540.48 531.10 Td (expected ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 519.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.35 519.10 Td (change ) Tj ET Q q 0 0 0 rg BT 77.23 519.10 Td (for ) Tj ET Q q 0 0 0 rg BT 91.46 519.10 Td (typical ) Tj ET Q q 0 0 0 rg BT 121.24 519.10 Td (net ) Tj ET Q q 0 0 0 rg BT 136.02 519.10 Td (product ) Tj ET Q q 0 0 0 rg BT 169.13 519.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 191.14 519.10 Td (to ) Tj ET Q q 0 0 0 rg BT 201.49 519.10 Td (customers, ) Tj ET Q q 0 0 0 rg BT 247.10 519.10 Td (most ) Tj ET Q q 0 0 0 rg BT 269.12 519.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 303.35 519.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 337.00 519.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 393.43 519.10 Td (as ) Tj ET Q q 0 0 0 rg BT 404.33 519.10 Td (well ) Tj ET Q q 0 0 0 rg BT 424.12 519.10 Td (as ) Tj ET Q q 0 0 0 rg BT 435.01 519.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 472.01 519.10 Td (and ) Tj ET Q q 0 0 0 rg BT 489.02 519.10 Td (sale-based ) Tj ET Q q 0 0 0 rg BT 533.23 519.10 Td (milestones ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 507.10 Td (from ) Tj ET Q q 0 0 0 rg BT 57.97 507.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 112.70 507.10 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 171.59 507.10 Td (In ) Tj ET Q q 0 0 0 rg BT 182.45 507.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 220.25 507.10 Td (the ) Tj ET Q q 0 0 0 rg BT 234.99 507.10 Td (timing ) Tj ET Q q 0 0 0 rg BT 263.63 507.10 Td (of ) Tj ET Q q 0 0 0 rg BT 274.49 507.10 Td (recognizing ) Tj ET Q q 0 0 0 rg BT 324.22 507.10 Td (royalties, ) Tj ET Q q 0 0 0 rg BT 363.68 507.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 411.74 507.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 457.04 507.10 Td (and ) Tj ET Q q 0 0 0 rg BT 474.01 507.10 Td (other ) Tj ET Q q 0 0 0 rg BT 497.08 507.10 Td (forms ) Tj ET Q q 0 0 0 rg BT 522.94 507.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.80 507.10 Td (contingent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 495.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 92.37 495.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 129.87 495.10 Td (from ) Tj ET Q q 0 0 0 rg BT 151.81 495.10 Td (the ) Tj ET Q q 0 0 0 rg BT 166.52 495.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 211.23 495.10 Td (of ) Tj ET Q q 0 0 0 rg BT 222.06 495.10 Td (businesses ) Tj ET Q q 0 0 0 rg BT 266.79 495.10 Td (is ) Tj ET Q q 0 0 0 rg BT 275.96 495.10 Td (not ) Tj ET Q q 0 0 0 rg BT 291.23 495.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 329.27 495.10 Td (to ) Tj ET Q q 0 0 0 rg BT 339.54 495.10 Td (change. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 471.10 Td (However) Tj ET Q q 0 0 0 rg BT 72.25 471.10 Td (, ) Tj ET Q q 0 0 0 rg BT 77.52 471.10 Td (transaction ) Tj ET Q q 0 0 0 rg BT 124.15 471.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 150.80 471.10 Td (are ) Tj ET Q q 0 0 0 rg BT 165.77 471.10 Td (no ) Tj ET Q q 0 0 0 rg BT 178.54 471.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 206.85 471.10 Td (required ) Tj ET Q q 0 0 0 rg BT 242.93 471.10 Td (to ) Tj ET Q q 0 0 0 rg BT 253.48 471.10 Td (be ) Tj ET Q q 0 0 0 rg BT 265.68 471.10 Td (fixed ) Tj ET Q q 0 0 0 rg BT 288.99 471.10 Td (or ) Tj ET Q q 0 0 0 rg BT 300.09 471.10 Td (determinable ) Tj ET Q q 0 0 0 rg BT 355.05 471.10 Td (and ) Tj ET Q q 0 0 0 rg BT 372.26 471.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 402.23 471.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 437.19 471.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 493.83 471.10 Td (might ) Tj ET Q q 0 0 0 rg BT 519.93 471.10 Td (be ) Tj ET Q q 0 0 0 rg BT 532.14 471.10 Td (recognized ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 459.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 57.21 459.10 Td (to ) Tj ET Q q 0 0 0 rg BT 66.75 459.10 Td (the ) Tj ET Q q 0 0 0 rg BT 80.74 459.10 Td (occurrence ) Tj ET Q q 0 0 0 rg BT 126.36 459.10 Td (or ) Tj ET Q q 0 0 0 rg BT 136.45 459.10 Td (resolution ) Tj ET Q q 0 0 0 rg BT 178.22 459.10 Td (of ) Tj ET Q q 0 0 0 rg BT 188.31 459.10 Td (the ) Tj ET Q q 0 0 0 rg BT 202.30 459.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 246.28 459.10 Td (event ) Tj ET Q q 0 0 0 rg BT 269.70 459.10 Td (to ) Tj ET Q q 0 0 0 rg BT 279.25 459.10 Td (the ) Tj ET Q q 0 0 0 rg BT 293.23 459.10 Td (extent ) Tj ET Q q 0 0 0 rg BT 319.43 459.10 Td (it ) Tj ET Q q 0 0 0 rg BT 326.76 459.10 Td (is ) Tj ET Q q 0 0 0 rg BT 335.19 459.10 Td (probable ) Tj ET Q q 0 0 0 rg BT 371.95 459.10 Td (that ) Tj ET Q q 0 0 0 rg BT 388.71 459.10 Td (a ) Tj ET Q q 0 0 0 rg BT 394.92 459.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 438.90 459.10 Td (reversal ) Tj ET Q q 0 0 0 rg BT 472.31 459.10 Td (in ) Tj ET Q q 0 0 0 rg BT 481.85 459.10 Td (the ) Tj ET Q q 0 0 0 rg BT 495.84 459.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 527.60 459.10 Td (of ) Tj ET Q q 0 0 0 rg BT 537.70 459.10 Td (estimated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 447.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 83.00 447.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 117.23 447.10 Td (will ) Tj ET Q q 0 0 0 rg BT 135.36 447.10 Td (not ) Tj ET Q q 0 0 0 rg BT 150.71 447.10 Td (occur) Tj ET Q q 0 0 0 rg BT 172.37 447.10 Td (. ) Tj ET Q q 0 0 0 rg BT 177.44 447.10 Td (Certain ) Tj ET Q q 0 0 0 rg BT 209.45 447.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 250.35 447.10 Td (future ) Tj ET Q q 0 0 0 rg BT 276.80 447.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 313.81 447.10 Td (and ) Tj ET Q q 0 0 0 rg BT 330.82 447.10 Td (termination ) Tj ET Q q 0 0 0 rg BT 379.50 447.10 Td (fees ) Tj ET Q q 0 0 0 rg BT 398.17 447.10 Td (for ) Tj ET Q q 0 0 0 rg BT 412.41 447.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 451.09 447.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 476.44 447.10 Td (previously ) Tj ET Q q 0 0 0 rg BT 521.23 447.10 Td (reacquired ) Tj ET Q q 0 0 0 rg BT 566.00 447.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 435.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 70.58 435.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 106.27 435.10 Td (are ) Tj ET Q q 0 0 0 rg BT 121.97 435.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 160.99 435.10 Td (to ) Tj ET Q q 0 0 0 rg BT 172.26 435.10 Td (be ) Tj ET Q q 0 0 0 rg BT 185.18 435.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 232.54 435.10 Td (as ) Tj ET Q q 0 0 0 rg BT 244.35 435.10 Td (contract ) Tj ET Q q 0 0 0 rg BT 280.05 435.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 306.86 435.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 330.35 435.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 368.84 435.10 Td (of ) Tj ET Q q 0 0 0 rg BT 380.66 435.10 Td (the ) Tj ET Q q 0 0 0 rg BT 396.36 435.10 Td (new ) Tj ET Q q 0 0 0 rg BT 416.51 435.10 Td (standard. ) Tj ET Q q 0 0 0 rg BT 456.38 435.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 482.07 435.10 Td (to ) Tj ET Q q 0 0 0 rg BT 493.34 435.10 Td (the ) Tj ET Q q 0 0 0 rg BT 509.04 435.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 538.64 435.10 Td (and ) Tj ET Q q 0 0 0 rg BT 556.57 435.10 Td (Lilly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 423.10 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 92.49 423.10 Td (in ) Tj ET Q q 0 0 0 rg BT 102.89 423.10 Td ("—Note ) Tj ET Q q 0 0 0 rg BT 139.04 423.10 Td (3. ) Tj ET Q q 0 0 0 rg BT 148.59 423.10 Td (Alliances". ) Tj ET Q q 0 0 0 rg BT 194.98 423.10 Td (As ) Tj ET Q q 0 0 0 rg BT 208.72 423.10 Td (a ) Tj ET Q q 0 0 0 rg BT 215.79 423.10 Td (result ) Tj ET Q q 0 0 0 rg BT 240.63 423.10 Td (of ) Tj ET Q q 0 0 0 rg BT 251.59 423.10 Td (the ) Tj ET Q q 0 0 0 rg BT 266.43 423.10 Td (new ) Tj ET Q q 0 0 0 rg BT 285.72 423.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 324.44 423.10 Td (and ) Tj ET Q q 0 0 0 rg BT 341.51 423.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 388.56 423.10 Td (ef) Tj ET Q q 0 0 0 rg BT 396.15 423.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 413.76 423.10 Td (adjustment, ) Tj ET Q q 0 0 0 rg BT 462.77 423.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 497.04 423.10 Td (and ) Tj ET Q q 0 0 0 rg BT 514.11 423.10 Td (other ) Tj ET Q q 0 0 0 rg BT 537.28 423.10 Td (income ) Tj ET Q q 0 0 0 rg BT 569.34 423.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 411.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 73.60 411.10 Td (to ) Tj ET Q q 0 0 0 rg BT 83.45 411.10 Td (be ) Tj ET Q q 0 0 0 rg BT 94.95 411.10 Td (lower ) Tj ET Q q 0 0 0 rg BT 119.79 411.10 Td (in ) Tj ET Q q 0 0 0 rg BT 129.64 411.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 151.70 411.10 Td (by ) Tj ET Q q 0 0 0 rg BT 163.77 411.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.60 411.10 Td ($200 ) Tj ET Q q 0 0 0 rg BT 245.67 411.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 274.56 411.10 Td ( ) Tj ET Q q 0 0 0 rg BT 276.63 411.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 293.13 411.10 Td ($125 ) Tj ET Q q 0 0 0 rg BT 315.20 411.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.09 411.10 Td (, ) Tj ET Q q 0 0 0 rg BT 348.66 411.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 396.32 411.10 Td (, ) Tj ET Q q 0 0 0 rg BT 400.89 411.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 442.38 411.10 Td (to ) Tj ET Q q 0 0 0 rg BT 452.23 411.10 Td (what ) Tj ET Q q 0 0 0 rg BT 473.73 411.10 Td (would ) Tj ET Q q 0 0 0 rg BT 500.80 411.10 Td (have ) Tj ET Q q 0 0 0 rg BT 521.74 411.10 Td (been ) Tj ET Q q 0 0 0 rg BT 542.69 411.10 Td (reported ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 399.10 Td (under ) Tj ET Q q 0 0 0 rg BT 61.27 399.10 Td (the ) Tj ET Q q 0 0 0 rg BT 75.99 399.10 Td (previous ) Tj ET Q q 0 0 0 rg BT 112.92 399.10 Td (standard. ) Tj ET Q q 0 0 0 rg BT 151.80 399.10 Td (No ) Tj ET Q q 0 0 0 rg BT 166.52 399.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 211.23 399.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 245.94 399.10 Td (to ) Tj ET Q q 0 0 0 rg BT 256.22 399.10 Td (business ) Tj ET Q q 0 0 0 rg BT 292.61 399.10 Td (processes, ) Tj ET Q q 0 0 0 rg BT 335.93 399.10 Td (systems ) Tj ET Q q 0 0 0 rg BT 370.10 399.10 Td (and ) Tj ET Q q 0 0 0 rg BT 387.04 399.10 Td (controls ) Tj ET Q q 0 0 0 rg BT 421.76 399.10 Td (are ) Tj ET Q q 0 0 0 rg BT 436.46 399.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 474.50 399.10 Td (to ) Tj ET Q q 0 0 0 rg BT 484.77 399.10 Td (be ) Tj ET Q q 0 0 0 rg BT 496.71 399.10 Td (required. ) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 373.7669921875 m 294.515625 373.7669921875 l s q 0 0 0 rg BT 36.00 375.10 Td (Gains and Losses fr) Tj ET Q q 0 0 0 rg BT 115.37 375.10 Td (om the Der) Tj ET Q q 0 0 0 rg BT 159.98 375.10 Td (ecognition of Nonfinancial ) Tj ET Q q 0 0 0 rg BT 269.52 375.10 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 360.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.48 360.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 116.17 360.10 Td (for ) Tj ET Q q 0 0 0 rg BT 130.43 360.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 154.14 360.10 Td (and ) Tj ET Q q 0 0 0 rg BT 171.18 360.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 197.67 360.10 Td (from ) Tj ET Q q 0 0 0 rg BT 219.71 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 234.53 360.10 Td (derecognition ) Tj ET Q q 0 0 0 rg BT 292.11 360.10 Td (of ) Tj ET Q q 0 0 0 rg BT 303.04 360.10 Td (nonfinancial ) Tj ET Q q 0 0 0 rg BT 355.62 360.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 381.55 360.10 Td (will ) Tj ET Q q 0 0 0 rg BT 399.70 360.10 Td (be ) Tj ET Q q 0 0 0 rg BT 411.74 360.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 446.00 360.10 Td (in ) Tj ET Q q 0 0 0 rg BT 456.38 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 471.19 360.10 Td (first ) Tj ET Q q 0 0 0 rg BT 489.90 360.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 520.82 360.10 Td (of ) Tj ET Q q 0 0 0 rg BT 531.75 360.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 554.35 360.10 Td (using ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.43 348.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 88.74 348.10 Td (retrospective ) Tj ET Q q 0 0 0 rg BT 142.60 348.10 Td (method. ) Tj ET Q q 0 0 0 rg BT 177.14 348.10 Td (The ) Tj ET Q q 0 0 0 rg BT 194.90 348.10 Td (amendments ) Tj ET Q q 0 0 0 rg BT 247.66 348.10 Td (clarify ) Tj ET Q q 0 0 0 rg BT 275.96 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 290.39 348.10 Td (scope ) Tj ET Q q 0 0 0 rg BT 315.37 348.10 Td (of ) Tj ET Q q 0 0 0 rg BT 325.91 348.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 347.56 348.10 Td (derecognition ) Tj ET Q q 0 0 0 rg BT 404.76 348.10 Td (guidance, ) Tj ET Q q 0 0 0 rg BT 445.56 348.10 Td (adds ) Tj ET Q q 0 0 0 rg BT 466.10 348.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 504.41 348.10 Td (for ) Tj ET Q q 0 0 0 rg BT 518.28 348.10 Td (partial ) Tj ET Q q 0 0 0 rg BT 546.04 348.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 567.69 348.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 336.10 Td (nonfinancial ) Tj ET Q q 0 0 0 rg BT 88.92 336.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 115.18 336.10 Td (and ) Tj ET Q q 0 0 0 rg BT 132.55 336.10 Td (clarifies ) Tj ET Q q 0 0 0 rg BT 167.69 336.10 Td (recognizing ) Tj ET Q q 0 0 0 rg BT 217.83 336.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 241.87 336.10 Td (and ) Tj ET Q q 0 0 0 rg BT 259.24 336.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 286.07 336.10 Td (from ) Tj ET Q q 0 0 0 rg BT 308.44 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 323.59 336.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 357.06 336.10 Td (of ) Tj ET Q q 0 0 0 rg BT 368.33 336.10 Td (nonfinancial ) Tj ET Q q 0 0 0 rg BT 421.24 336.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 447.51 336.10 Td (in ) Tj ET Q q 0 0 0 rg BT 458.22 336.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 497.25 336.10 Td (with ) Tj ET Q q 0 0 0 rg BT 517.96 336.10 Td (noncustomers. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 324.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.38 324.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 91.31 324.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 129.23 324.10 Td (clarifies ) Tj ET Q q 0 0 0 rg BT 163.27 324.10 Td (that ) Tj ET Q q 0 0 0 rg BT 180.10 324.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 209.13 324.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 258.73 324.10 Td (such ) Tj ET Q q 0 0 0 rg BT 278.90 324.10 Td (as ) Tj ET Q q 0 0 0 rg BT 289.06 324.10 Td (the ) Tj ET Q q 0 0 0 rg BT 303.11 324.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 320.49 324.10 Td (or ) Tj ET Q q 0 0 0 rg BT 330.65 324.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 384.70 324.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.86 324.10 Td (product ) Tj ET Q q 0 0 0 rg BT 427.24 324.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 451.85 324.10 Td (that ) Tj ET Q q 0 0 0 rg BT 468.68 324.10 Td (do ) Tj ET Q q 0 0 0 rg BT 480.52 324.10 Td (not ) Tj ET Q q 0 0 0 rg BT 495.13 324.10 Td (constitute ) Tj ET Q q 0 0 0 rg BT 535.84 324.10 Td (a ) Tj ET Q q 0 0 0 rg BT 542.12 324.10 Td (business ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 312.10 Td (will ) Tj ET Q q 0 0 0 rg BT 54.54 312.10 Td (require ) Tj ET Q q 0 0 0 rg BT 85.84 312.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 132.70 312.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 163.46 312.10 Td (to ) Tj ET Q q 0 0 0 rg BT 173.57 312.10 Td (ASC ) Tj ET Q q 0 0 0 rg BT 196.00 312.10 Td (606 ) Tj ET Q q 0 0 0 rg BT 213.99 312.10 Td (including ) Tj ET Q q 0 0 0 rg BT 254.75 312.10 Td (the ) Tj ET Q q 0 0 0 rg BT 269.95 312.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 307.93 312.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 356.46 312.10 Td (of ) Tj ET Q q 0 0 0 rg BT 367.77 312.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 402.96 312.10 Td (consideration. ) Tj ET Q q 0 0 0 rg BT 462.10 312.10 Td (The ) Tj ET Q q 0 0 0 rg BT 480.64 312.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 519.71 312.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 558.79 312.10 Td (may ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 300.10 Td (result ) Tj ET Q q 0 0 0 rg BT 60.72 300.10 Td (in ) Tj ET Q q 0 0 0 rg BT 71.00 300.10 Td (earlier ) Tj ET Q q 0 0 0 rg BT 99.03 300.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 147.07 300.10 Td (of ) Tj ET Q q 0 0 0 rg BT 157.90 300.10 Td (variable ) Tj ET Q q 0 0 0 rg BT 192.60 300.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 248.97 300.10 Td (depending ) Tj ET Q q 0 0 0 rg BT 293.13 300.10 Td (on ) Tj ET Q q 0 0 0 rg BT 305.63 300.10 Td (the ) Tj ET Q q 0 0 0 rg BT 320.35 300.10 Td (facts ) Tj ET Q q 0 0 0 rg BT 341.72 300.10 Td (and ) Tj ET Q q 0 0 0 rg BT 358.66 300.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 417.80 300.10 Td (of ) Tj ET Q q 0 0 0 rg BT 428.63 300.10 Td (each ) Tj ET Q q 0 0 0 rg BT 449.45 300.10 Td (transaction.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 278.7669921875 m 298.451171875 278.7669921875 l s q 0 0 0 rg BT 36.00 280.10 Td (Pr) Tj ET Q q 0 0 0 rg BT 45.63 280.10 Td (esentation ) Tj ET Q q 0 0 0 rg BT 89.23 280.10 Td (of ) Tj ET Q q 0 0 0 rg BT 99.51 280.10 Td (Net ) Tj ET Q q 0 0 0 rg BT 115.90 280.10 Td (Periodic ) Tj ET Q q 0 0 0 rg BT 152.83 280.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 187.55 280.10 Td (and ) Tj ET Q q 0 0 0 rg BT 205.05 280.10 Td (Postr) Tj ET Q q 0 0 0 rg BT 226.35 280.10 Td (etir) Tj ET Q q 0 0 0 rg BT 239.86 280.10 Td (ement ) Tj ET Q q 0 0 0 rg BT 266.24 280.10 Td (Benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 265.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.53 265.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 116.29 265.10 Td (requiring ) Tj ET Q q 0 0 0 rg BT 155.60 265.10 Td (all ) Tj ET Q q 0 0 0 rg BT 168.25 265.10 Td (net ) Tj ET Q q 0 0 0 rg BT 183.13 265.10 Td (periodic ) Tj ET Q q 0 0 0 rg BT 218.55 265.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 248.97 265.10 Td (components ) Tj ET Q q 0 0 0 rg BT 299.95 265.10 Td (for ) Tj ET Q q 0 0 0 rg BT 314.27 265.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 346.91 265.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 377.33 265.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 411.10 265.10 Td (and ) Tj ET Q q 0 0 0 rg BT 428.20 265.10 Td (other ) Tj ET Q q 0 0 0 rg BT 451.40 265.10 Td (postretirement ) Tj ET Q q 0 0 0 rg BT 511.82 265.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 535.58 265.10 Td (other ) Tj ET Q q 0 0 0 rg BT 558.79 265.10 Td (than ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 253.10 Td (service ) Tj ET Q q 0 0 0 rg BT 66.04 253.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 87.76 253.10 Td (to ) Tj ET Q q 0 0 0 rg BT 97.26 253.10 Td (be ) Tj ET Q q 0 0 0 rg BT 108.43 253.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 145.13 253.10 Td (outside ) Tj ET Q q 0 0 0 rg BT 175.74 253.10 Td (of ) Tj ET Q q 0 0 0 rg BT 185.79 253.10 Td (income ) Tj ET Q q 0 0 0 rg BT 216.95 253.10 Td (from ) Tj ET Q q 0 0 0 rg BT 238.11 253.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 281.49 253.10 Td (\(other ) Tj ET Q q 0 0 0 rg BT 307.09 253.10 Td (income\) ) Tj ET Q q 0 0 0 rg BT 341.58 253.10 Td (will ) Tj ET Q q 0 0 0 rg BT 358.86 253.10 Td (be ) Tj ET Q q 0 0 0 rg BT 370.02 253.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 403.40 253.10 Td (in ) Tj ET Q q 0 0 0 rg BT 412.90 253.10 Td (the ) Tj ET Q q 0 0 0 rg BT 426.84 253.10 Td (first ) Tj ET Q q 0 0 0 rg BT 444.67 253.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 474.71 253.10 Td (of ) Tj ET Q q 0 0 0 rg BT 484.76 253.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 506.49 253.10 Td (on ) Tj ET Q q 0 0 0 rg BT 518.21 253.10 Td (a ) Tj ET Q q 0 0 0 rg BT 524.37 253.10 Td (retrospective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.10 Td (basis. ) Tj ET Q q 0 0 0 rg BT 61.52 241.10 Td (The ) Tj ET Q q 0 0 0 rg BT 80.33 241.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 122.47 241.10 Td (expects ) Tj ET Q q 0 0 0 rg BT 155.72 241.10 Td (that ) Tj ET Q q 0 0 0 rg BT 173.97 241.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 203.88 241.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 223.25 241.10 Td (of ) Tj ET Q q 0 0 0 rg BT 234.84 241.10 Td (products ) Tj ET Q q 0 0 0 rg BT 272.54 241.10 Td (sold; ) Tj ET Q q 0 0 0 rg BT 295.24 241.10 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 341.54 241.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 371.47 241.10 Td (and ) Tj ET Q q 0 0 0 rg BT 389.16 241.10 Td (administrative; ) Tj ET Q q 0 0 0 rg BT 452.41 241.10 Td (and ) Tj ET Q q 0 0 0 rg BT 470.10 241.10 Td (research ) Tj ET Q q 0 0 0 rg BT 506.67 241.10 Td (and ) Tj ET Q q 0 0 0 rg BT 524.36 241.10 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 229.10 Td (expenses ) Tj ET Q q 0 0 0 rg BT 74.84 229.10 Td (will ) Tj ET Q q 0 0 0 rg BT 93.13 229.10 Td (increase ) Tj ET Q q 0 0 0 rg BT 128.62 229.10 Td (in ) Tj ET Q q 0 0 0 rg BT 139.13 229.10 Td (the ) Tj ET Q q 0 0 0 rg BT 154.09 229.10 Td (aggregate ) Tj ET Q q 0 0 0 rg BT 195.69 229.10 Td (with ) Tj ET Q q 0 0 0 rg BT 216.20 229.10 Td (a ) Tj ET Q q 0 0 0 rg BT 223.38 229.10 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 283.32 229.10 Td (of) Tj ET Q q 0 0 0 rg BT 291.47 229.10 Td (fset ) Tj ET Q q 0 0 0 rg BT 308.65 229.10 Td (in ) Tj ET Q q 0 0 0 rg BT 319.16 229.10 Td (other ) Tj ET Q q 0 0 0 rg BT 342.45 229.10 Td (income. ) Tj ET Q q 0 0 0 rg BT 376.92 229.10 Td (The ) Tj ET Q q 0 0 0 rg BT 395.20 229.10 Td (service ) Tj ET Q q 0 0 0 rg BT 426.25 229.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 445.10 229.10 Td (component ) Tj ET Q q 0 0 0 rg BT 492.27 229.10 Td (will ) Tj ET Q q 0 0 0 rg BT 510.56 229.10 Td (also ) Tj ET Q q 0 0 0 rg BT 529.41 229.10 Td (be ) Tj ET Q q 0 0 0 rg BT 541.58 229.10 Td (included ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 217.10 Td (other ) Tj ET Q q 0 0 0 rg BT 69.33 217.10 Td (income ) Tj ET Q q 0 0 0 rg BT 101.26 217.10 Td (as ) Tj ET Q q 0 0 0 rg BT 112.09 217.10 Td (the ) Tj ET Q q 0 0 0 rg BT 126.81 217.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 163.19 217.10 Td (are ) Tj ET Q q 0 0 0 rg BT 177.90 217.10 Td (not ) Tj ET Q q 0 0 0 rg BT 193.18 217.10 Td (material.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (As ) Tj ET Q q 0 0 0 rg BT 49.61 197.10 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 85.44 197.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 121.83 197.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 144.33 197.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 181.82 197.10 Td (of ) Tj ET Q q 0 0 0 rg BT 192.65 197.10 Td (the ) Tj ET Q q 0 0 0 rg BT 207.37 197.10 Td (new ) Tj ET Q q 0 0 0 rg BT 226.53 197.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 265.12 197.10 Td (are ) Tj ET Q q 0 0 0 rg BT 279.83 197.10 Td (as ) Tj ET Q q 0 0 0 rg BT 290.66 197.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 60.50 138.60 274.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 334.50 138.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 338.50 138.60 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 138.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 392.50 138.60 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 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3 M 338.5 168.60000000000002 m 388.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 168.60000000000002 m 392.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 168.60000000000002 m 442.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 442.5 168.60000000000002 m 446.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 168.60000000000002 m 496.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 168.60000000000002 m 500.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 500.5 168.60000000000002 m 550.5 168.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 338.5 153.60000000000002 m 388.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 153.60000000000002 m 392.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 153.60000000000002 m 442.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 153.60000000000002 m 496.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 153.60000000000002 m 500.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 500.5 153.60000000000002 m 550.5 153.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 338.5 138.60000000000002 m 388.5 138.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 392.5 138.60000000000002 m 442.5 138.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 138.60000000000002 m 496.5 138.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 500.5 138.60000000000002 m 550.5 138.60000000000002 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 399.70 172.83 Td (Y) Tj ET Q q 0 0 0 rg BT 404.59 172.83 Td (ear) Tj ET Q q 0 0 0 rg BT 415.55 172.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 476.28 172.83 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 382.00 157.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 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128.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.15 128.27 Td (4,967) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 113.27 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.15 113.27 Td (4,687) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.15 113.27 Td (4,733) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 113.27 Td (4,91) Tj ET Q q 0 0 0 rg BT 487.65 113.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.15 113.27 Td (4,960) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 98.27 Td (Research and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.15 98.27 Td (6,41) Tj ET Q q 0 0 0 rg BT 379.65 98.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.15 98.27 Td (6,474) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.15 98.27 Td (4,940) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.15 98.27 Td (5,005) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 83.27 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 358.80 83.32 Td (\(1,519) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.65 83.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.80 83.32 Td (\(1,654) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.65 83.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.80 83.32 Td (\(1,285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 83.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.80 83.32 Td (\(1,420) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.65 83.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 129 0 obj <> endobj 130 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (64) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 131.830078125 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Definition ) Tj ET Q q 0 0 0 rg BT 79.05 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 89.33 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 96.83 749.10 Td (Business) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 734.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.52 734.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 116.25 734.10 Td (that ) Tj ET Q q 0 0 0 rg BT 133.89 734.10 Td (revises ) Tj ET Q q 0 0 0 rg BT 164.30 734.10 Td (the ) Tj ET Q q 0 0 0 rg BT 179.16 734.10 Td (definition ) Tj ET Q q 0 0 0 rg BT 220.68 734.10 Td (of ) Tj ET Q q 0 0 0 rg BT 231.65 734.10 Td (a ) Tj ET Q q 0 0 0 rg BT 238.73 734.10 Td (business ) Tj ET Q q 0 0 0 rg BT 275.27 734.10 Td (will ) Tj ET Q q 0 0 0 rg BT 293.47 734.10 Td (be ) Tj ET Q q 0 0 0 rg BT 305.55 734.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 339.84 734.10 Td (prospectively ) Tj ET Q q 0 0 0 rg BT 396.36 734.10 Td (in ) Tj ET Q q 0 0 0 rg BT 406.78 734.10 Td (the ) Tj ET Q q 0 0 0 rg BT 421.63 734.10 Td (first ) Tj ET Q q 0 0 0 rg BT 440.38 734.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 471.34 734.10 Td (of ) Tj ET Q q 0 0 0 rg BT 482.31 734.10 Td (2018. ) Tj ET Q q 0 0 0 rg BT 507.26 734.10 Td (The ) Tj ET Q q 0 0 0 rg BT 525.45 734.10 Td (amendments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 722.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 68.75 722.10 Td (an ) Tj ET Q q 0 0 0 rg BT 80.40 722.10 Td (initial ) Tj ET Q q 0 0 0 rg BT 105.93 722.10 Td (screen ) Tj ET Q q 0 0 0 rg BT 133.68 722.10 Td (that ) Tj ET Q q 0 0 0 rg BT 150.88 722.10 Td (when ) Tj ET Q q 0 0 0 rg BT 174.74 722.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 227.50 722.10 Td (all ) Tj ET Q q 0 0 0 rg BT 239.70 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 250.24 722.10 Td (the ) Tj ET Q q 0 0 0 rg BT 264.66 722.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 280.75 722.10 Td (value ) Tj ET Q q 0 0 0 rg BT 304.61 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 315.14 722.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.57 722.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 352.88 722.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 378.42 722.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 415.05 722.10 Td (or ) Tj ET Q q 0 0 0 rg BT 425.59 722.10 Td (disposed ) Tj ET Q q 0 0 0 rg BT 462.79 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 473.33 722.10 Td (is ) Tj ET Q q 0 0 0 rg BT 482.21 722.10 Td (concentrated ) Tj ET Q q 0 0 0 rg BT 535.49 722.10 Td (in ) Tj ET Q q 0 0 0 rg BT 545.47 722.10 Td (a ) Tj ET Q q 0 0 0 rg BT 552.12 722.10 Td (single ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 710.10 Td (identifiable ) Tj ET Q q 0 0 0 rg BT 84.02 710.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 105.94 710.10 Td (or ) Tj ET Q q 0 0 0 rg BT 116.75 710.10 Td (a ) Tj ET Q q 0 0 0 rg BT 123.67 710.10 Td (group ) Tj ET Q q 0 0 0 rg BT 149.48 710.10 Td (of ) Tj ET Q q 0 0 0 rg BT 160.30 710.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 190.55 710.10 Td (identifiable ) Tj ET Q q 0 0 0 rg BT 238.57 710.10 Td (assets, ) Tj ET Q q 0 0 0 rg BT 266.88 710.10 Td (an ) Tj ET Q q 0 0 0 rg BT 278.80 710.10 Td (integrated ) Tj ET Q q 0 0 0 rg BT 321.27 710.10 Td (set ) Tj ET Q q 0 0 0 rg BT 334.86 710.10 Td (of ) Tj ET Q q 0 0 0 rg BT 345.67 710.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 371.48 710.10 Td (and ) Tj ET Q q 0 0 0 rg BT 388.40 710.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 426.98 710.10 Td (would ) Tj ET Q q 0 0 0 rg BT 454.46 710.10 Td (not ) Tj ET Q q 0 0 0 rg BT 469.72 710.10 Td (represent ) Tj ET Q q 0 0 0 rg BT 508.85 710.10 Td (a ) Tj ET Q q 0 0 0 rg BT 515.77 710.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 554.64 710.10 Td (If ) Tj ET Q q 0 0 0 rg BT 563.79 710.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 698.10 Td (screen ) Tj ET Q q 0 0 0 rg BT 64.54 698.10 Td (is ) Tj ET Q q 0 0 0 rg BT 74.21 698.10 Td (not ) Tj ET Q q 0 0 0 rg BT 89.98 698.10 Td (met, ) Tj ET Q q 0 0 0 rg BT 110.48 698.10 Td (the ) Tj ET Q q 0 0 0 rg BT 125.69 698.10 Td (set ) Tj ET Q q 0 0 0 rg BT 139.80 698.10 Td (must ) Tj ET Q q 0 0 0 rg BT 162.25 698.10 Td (include ) Tj ET Q q 0 0 0 rg BT 194.68 698.10 Td (an ) Tj ET Q q 0 0 0 rg BT 207.12 698.10 Td (input ) Tj ET Q q 0 0 0 rg BT 230.68 698.10 Td (and ) Tj ET Q q 0 0 0 rg BT 248.12 698.10 Td (a ) Tj ET Q q 0 0 0 rg BT 255.55 698.10 Td (substantive ) Tj ET Q q 0 0 0 rg BT 303.55 698.10 Td (process ) Tj ET Q q 0 0 0 rg BT 336.54 698.10 Td (that ) Tj ET Q q 0 0 0 rg BT 354.53 698.10 Td (together ) Tj ET Q q 0 0 0 rg BT 390.30 698.10 Td (significantly ) Tj ET Q q 0 0 0 rg BT 443.29 698.10 Td (contribute ) Tj ET Q q 0 0 0 rg BT 486.83 698.10 Td (to ) Tj ET Q q 0 0 0 rg BT 497.60 698.10 Td (the ) Tj ET Q q 0 0 0 rg BT 512.82 698.10 Td (ability ) Tj ET Q q 0 0 0 rg BT 541.37 698.10 Td (to ) Tj ET Q q 0 0 0 rg BT 552.15 698.10 Td (create ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 686.10 Td (outputs ) Tj ET Q q 0 0 0 rg BT 67.94 686.10 Td (for ) Tj ET Q q 0 0 0 rg BT 82.09 686.10 Td (the ) Tj ET Q q 0 0 0 rg BT 96.80 686.10 Td (set ) Tj ET Q q 0 0 0 rg BT 110.39 686.10 Td (to ) Tj ET Q q 0 0 0 rg BT 120.66 686.10 Td (represent ) Tj ET Q q 0 0 0 rg BT 159.80 686.10 Td (a ) Tj ET Q q 0 0 0 rg BT 166.73 686.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 205.43 686.10 Td (The ) Tj ET Q q 0 0 0 rg BT 223.47 686.10 Td (amendment ) Tj ET Q q 0 0 0 rg BT 272.61 686.10 Td (also ) Tj ET Q q 0 0 0 rg BT 291.21 686.10 Td (narrows ) Tj ET Q q 0 0 0 rg BT 325.91 686.10 Td (the ) Tj ET Q q 0 0 0 rg BT 340.61 686.10 Td (definition ) Tj ET Q q 0 0 0 rg BT 381.99 686.10 Td (of ) Tj ET Q q 0 0 0 rg BT 392.81 686.10 Td (the ) Tj ET Q q 0 0 0 rg BT 407.51 686.10 Td (term ) Tj ET Q q 0 0 0 rg BT 428.33 686.10 Td (output ) Tj ET Q q 0 0 0 rg BT 456.38 686.10 Td (and ) Tj ET Q q 0 0 0 rg BT 473.31 686.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 508.00 686.10 Td (the ) Tj ET Q q 0 0 0 rg BT 522.71 686.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 555.74 686.10 Td (of ) Tj ET Q q 0 0 0 rg BT 566.56 686.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 674.10 Td (or) Tj ET Q q 0 0 0 rg BT 44.15 674.10 Td (ganized ) Tj ET Q q 0 0 0 rg BT 77.50 674.10 Td (work ) Tj ET Q q 0 0 0 rg BT 100.31 674.10 Td (force ) Tj ET Q q 0 0 0 rg BT 123.11 674.10 Td (when ) Tj ET Q q 0 0 0 rg BT 147.03 674.10 Td (outputs ) Tj ET Q q 0 0 0 rg BT 178.74 674.10 Td (do ) Tj ET Q q 0 0 0 rg BT 191.00 674.10 Td (not ) Tj ET Q q 0 0 0 rg BT 206.04 674.10 Td (exist. ) Tj ET Q q 0 0 0 rg BT 229.52 674.10 Td (The ) Tj ET Q q 0 0 0 rg BT 247.33 674.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 285.68 674.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 324.03 674.10 Td (may ) Tj ET Q q 0 0 0 rg BT 343.51 674.10 Td (result ) Tj ET Q q 0 0 0 rg BT 367.99 674.10 Td (in ) Tj ET Q q 0 0 0 rg BT 378.02 674.10 Td (more ) Tj ET Q q 0 0 0 rg BT 400.83 674.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 450.85 674.10 Td (being ) Tj ET Q q 0 0 0 rg BT 475.33 674.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 518.12 674.10 Td (for ) Tj ET Q q 0 0 0 rg BT 532.04 674.10 Td (as ) Tj ET Q q 0 0 0 rg BT 542.63 674.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 568.22 674.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 662.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 662.10 Td (future ) Tj ET Q q 0 0 0 rg BT 77.09 662.10 Td (with ) Tj ET Q q 0 0 0 rg BT 97.37 662.10 Td (the ) Tj ET Q q 0 0 0 rg BT 112.09 662.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 141.80 662.10 Td (to ) Tj ET Q q 0 0 0 rg BT 152.08 662.10 Td (our ) Tj ET Q q 0 0 0 rg BT 167.91 662.10 Td (results ) Tj ET Q q 0 0 0 rg BT 196.52 662.10 Td (of ) Tj ET Q q 0 0 0 rg BT 207.35 662.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 251.50 662.10 Td (dependent ) Tj ET Q q 0 0 0 rg BT 295.10 662.10 Td (on ) Tj ET Q q 0 0 0 rg BT 307.60 662.10 Td (the ) Tj ET Q q 0 0 0 rg BT 322.31 662.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 365.37 662.10 Td (facts ) Tj ET Q q 0 0 0 rg BT 386.74 662.10 Td (and ) Tj ET Q q 0 0 0 rg BT 403.68 662.10 Td (circumstances ) Tj ET Q q 0 0 0 rg BT 462.82 662.10 Td (of ) Tj ET Q q 0 0 0 rg BT 473.65 662.10 Td (each ) Tj ET Q q 0 0 0 rg BT 494.47 662.10 Td (transaction.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 640.7669921875 m 297.9189453125 640.7669921875 l s q 0 0 0 rg BT 36.00 642.10 Td (Recognition ) Tj ET Q q 0 0 0 rg BT 86.82 642.10 Td (and ) Tj ET Q q 0 0 0 rg BT 104.32 642.10 Td (Measur) Tj ET Q q 0 0 0 rg BT 134.50 642.10 Td (ement ) Tj ET Q q 0 0 0 rg BT 160.88 642.10 Td (of ) Tj ET Q q 0 0 0 rg BT 171.16 642.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 212.36 642.10 Td (Assets ) Tj ET Q q 0 0 0 rg BT 239.86 642.10 Td (and ) Tj ET Q q 0 0 0 rg BT 257.36 642.10 Td (Liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 627.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 76.81 627.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 114.85 627.10 Td (for ) Tj ET Q q 0 0 0 rg BT 128.44 627.10 Td (the ) Tj ET Q q 0 0 0 rg BT 142.60 627.10 Td (recognition, ) Tj ET Q q 0 0 0 rg BT 192.58 627.10 Td (measurement, ) Tj ET Q q 0 0 0 rg BT 250.33 627.10 Td (presentation ) Tj ET Q q 0 0 0 rg BT 301.13 627.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.51 627.10 Td (disclosures ) Tj ET Q q 0 0 0 rg BT 363.89 627.10 Td (of ) Tj ET Q q 0 0 0 rg BT 374.15 627.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 411.07 627.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 459.67 627.10 Td (will ) Tj ET Q q 0 0 0 rg BT 477.17 627.10 Td (be ) Tj ET Q q 0 0 0 rg BT 488.54 627.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 522.14 627.10 Td (prospectively ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 615.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.79 615.10 Td (the ) Tj ET Q q 0 0 0 rg BT 62.01 615.10 Td (first ) Tj ET Q q 0 0 0 rg BT 81.12 615.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 112.45 615.10 Td (of ) Tj ET Q q 0 0 0 rg BT 123.78 615.10 Td (2018. ) Tj ET Q q 0 0 0 rg BT 149.07 615.10 Td (The ) Tj ET Q q 0 0 0 rg BT 167.63 615.10 Td (new ) Tj ET Q q 0 0 0 rg BT 187.29 615.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 226.39 615.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 261.61 615.10 Td (that ) Tj ET Q q 0 0 0 rg BT 279.61 615.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 296.49 615.10 Td (value ) Tj ET Q q 0 0 0 rg BT 321.16 615.10 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 371.94 615.10 Td (for ) Tj ET Q q 0 0 0 rg BT 386.60 615.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 414.60 615.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 455.38 615.10 Td (with ) Tj ET Q q 0 0 0 rg BT 476.16 615.10 Td (readily ) Tj ET Q q 0 0 0 rg BT 506.93 615.10 Td (determinable ) Tj ET Q q 0 0 0 rg BT 562.14 615.10 Td (fair ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 603.10 Td (values ) Tj ET Q q 0 0 0 rg BT 64.24 603.10 Td (currently ) Tj ET Q q 0 0 0 rg BT 103.03 603.10 Td (classified ) Tj ET Q q 0 0 0 rg BT 143.49 603.10 Td (as ) Tj ET Q q 0 0 0 rg BT 154.51 603.10 Td (available-for) Tj ET Q q 0 0 0 rg BT 205.39 603.10 Td (-sale ) Tj ET Q q 0 0 0 rg BT 226.96 603.10 Td (be ) Tj ET Q q 0 0 0 rg BT 239.09 603.10 Td (reported ) Tj ET Q q 0 0 0 rg BT 275.10 603.10 Td (through ) Tj ET Q q 0 0 0 rg BT 308.91 603.10 Td (earnings. ) Tj ET Q q 0 0 0 rg BT 347.78 603.10 Td (The ) Tj ET Q q 0 0 0 rg BT 366.02 603.10 Td (new ) Tj ET Q q 0 0 0 rg BT 385.38 603.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 424.17 603.10 Td (also ) Tj ET Q q 0 0 0 rg BT 442.97 603.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 477.87 603.10 Td (a ) Tj ET Q q 0 0 0 rg BT 485.00 603.10 Td (qualitative ) Tj ET Q q 0 0 0 rg BT 529.91 603.10 Td (impairment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 591.10 Td (assessment ) Tj ET Q q 0 0 0 rg BT 82.99 591.10 Td (for ) Tj ET Q q 0 0 0 rg BT 97.20 591.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 124.75 591.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 175.07 591.10 Td (without ) Tj ET Q q 0 0 0 rg BT 208.18 591.10 Td (a ) Tj ET Q q 0 0 0 rg BT 215.17 591.10 Td (readily ) Tj ET Q q 0 0 0 rg BT 245.48 591.10 Td (determinable ) Tj ET Q q 0 0 0 rg BT 300.23 591.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 316.66 591.10 Td (value ) Tj ET Q q 0 0 0 rg BT 340.87 591.10 Td (based ) Tj ET Q q 0 0 0 rg BT 366.19 591.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 388.74 591.10 Td (observable ) Tj ET Q q 0 0 0 rg BT 434.61 591.10 Td (price ) Tj ET Q q 0 0 0 rg BT 457.14 591.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 491.90 591.10 Td (and ) Tj ET Q q 0 0 0 rg BT 508.89 591.10 Td (a ) Tj ET Q q 0 0 0 rg BT 515.88 591.10 Td (char) Tj ET Q q 0 0 0 rg BT 532.91 591.10 Td (ge ) Tj ET Q q 0 0 0 rg BT 544.90 591.10 Td (through ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 579.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 72.22 579.10 Td (if ) Tj ET Q q 0 0 0 rg BT 80.67 579.10 Td (an ) Tj ET Q q 0 0 0 rg BT 92.45 579.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 140.89 579.10 Td (exists. ) Tj ET Q q 0 0 0 rg BT 168.34 579.10 Td (The ) Tj ET Q q 0 0 0 rg BT 186.23 579.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 224.66 579.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 263.10 579.10 Td (is ) Tj ET Q q 0 0 0 rg BT 272.11 579.10 Td (not ) Tj ET Q q 0 0 0 rg BT 287.23 579.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 325.10 579.10 Td (to ) Tj ET Q q 0 0 0 rg BT 335.22 579.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 378.10 579.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 407.65 579.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.21 579.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 463.88 579.10 Td (s ) Tj ET Q q 0 0 0 rg BT 470.11 579.10 Td (results ) Tj ET Q q 0 0 0 rg BT 498.56 579.10 Td (of ) Tj ET Q q 0 0 0 rg BT 509.23 579.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 553.23 579.10 Td (based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 567.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 58.50 567.10 Td (the ) Tj ET Q q 0 0 0 rg BT 73.22 567.10 Td (current ) Tj ET Q q 0 0 0 rg BT 104.03 567.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 131.53 567.10 Td (investment ) Tj ET Q q 0 0 0 rg BT 177.91 567.10 Td (portfolio.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 545.7669921875 m 172.1767578125 545.7669921875 l s q 0 0 0 rg BT 36.00 547.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 84.04 547.10 Td (for ) Tj ET Q q 0 0 0 rg BT 98.21 547.10 Td (Hedging ) Tj ET Q q 0 0 0 rg BT 134.97 547.10 Td (Activities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 532.10 Td (Amended ) Tj ET Q q 0 0 0 rg BT 77.72 532.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 116.65 532.10 Td (for ) Tj ET Q q 0 0 0 rg BT 131.15 532.10 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 177.86 532.10 Td (and ) Tj ET Q q 0 0 0 rg BT 195.14 532.10 Td (hedging ) Tj ET Q q 0 0 0 rg BT 230.19 532.10 Td (will ) Tj ET Q q 0 0 0 rg BT 248.59 532.10 Td (be ) Tj ET Q q 0 0 0 rg BT 260.87 532.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 295.36 532.10 Td (in ) Tj ET Q q 0 0 0 rg BT 305.98 532.10 Td (the ) Tj ET Q q 0 0 0 rg BT 321.04 532.10 Td (first ) Tj ET Q q 0 0 0 rg BT 339.98 532.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 371.14 532.10 Td (of ) Tj ET Q q 0 0 0 rg BT 382.31 532.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 405.15 532.10 Td (on ) Tj ET Q q 0 0 0 rg BT 417.99 532.10 Td (a ) Tj ET Q q 0 0 0 rg BT 425.27 532.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 464.21 532.10 Td (retrospective ) Tj ET Q q 0 0 0 rg BT 518.69 532.10 Td (approach. ) Tj ET Q q 0 0 0 rg BT 560.47 532.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 520.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 73.99 520.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 111.99 520.10 Td (revises ) Tj ET Q q 0 0 0 rg BT 141.66 520.10 Td (and ) Tj ET Q q 0 0 0 rg BT 158.00 520.10 Td (expands ) Tj ET Q q 0 0 0 rg BT 192.67 520.10 Td (items ) Tj ET Q q 0 0 0 rg BT 216.23 520.10 Td (eligible ) Tj ET Q q 0 0 0 rg BT 248.12 520.10 Td (for ) Tj ET Q q 0 0 0 rg BT 261.69 520.10 Td (hedge ) Tj ET Q q 0 0 0 rg BT 287.46 520.10 Td (accounting, ) Tj ET Q q 0 0 0 rg BT 335.74 520.10 Td (simplifies ) Tj ET Q q 0 0 0 rg BT 377.08 520.10 Td (hedge ) Tj ET Q q 0 0 0 rg BT 402.86 520.10 Td (ef) Tj ET Q q 0 0 0 rg BT 410.45 520.10 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 456.77 520.10 Td (testing ) Tj ET Q q 0 0 0 rg BT 485.34 520.10 Td (and ) Tj ET Q q 0 0 0 rg BT 501.68 520.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 535.78 520.10 Td (the ) Tj ET Q q 0 0 0 rg BT 549.90 520.10 Td (timing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 508.10 Td (of ) Tj ET Q q 0 0 0 rg BT 47.10 508.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 95.42 508.10 Td (and ) Tj ET Q q 0 0 0 rg BT 112.63 508.10 Td (presentation ) Tj ET Q q 0 0 0 rg BT 164.27 508.10 Td (for ) Tj ET Q q 0 0 0 rg BT 178.71 508.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 208.68 508.10 Td (hedged ) Tj ET Q q 0 0 0 rg BT 240.33 508.10 Td (items. ) Tj ET Q q 0 0 0 rg BT 267.27 508.10 Td (Certain ) Tj ET Q q 0 0 0 rg BT 299.47 508.10 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 342.79 508.10 Td (requirements ) Tj ET Q q 0 0 0 rg BT 397.77 508.10 Td (are ) Tj ET Q q 0 0 0 rg BT 412.75 508.10 Td (also ) Tj ET Q q 0 0 0 rg BT 431.63 508.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 470.50 508.10 Td (for ) Tj ET Q q 0 0 0 rg BT 484.94 508.10 Td (hedging ) Tj ET Q q 0 0 0 rg BT 519.92 508.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 558.80 508.10 Td (on ) Tj ET Q q 0 0 0 rg BT 571.57 508.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 496.10 Td (prospective ) Tj ET Q q 0 0 0 rg BT 84.59 496.10 Td (basis. ) Tj ET Q q 0 0 0 rg BT 109.41 496.10 Td (The ) Tj ET Q q 0 0 0 rg BT 127.46 496.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 166.05 496.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 204.65 496.10 Td (is ) Tj ET Q q 0 0 0 rg BT 213.82 496.10 Td (not ) Tj ET Q q 0 0 0 rg BT 229.10 496.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 267.13 496.10 Td (to ) Tj ET Q q 0 0 0 rg BT 277.41 496.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 320.44 496.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 350.16 496.10 Td (the ) Tj ET Q q 0 0 0 rg BT 364.87 496.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 406.54 496.10 Td (s ) Tj ET Q q 0 0 0 rg BT 412.93 496.10 Td (results ) Tj ET Q q 0 0 0 rg BT 441.54 496.10 Td (of ) Tj ET Q q 0 0 0 rg BT 452.37 496.10 Td (operations.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 474.7669921875 m 63.2216796875 474.7669921875 l s q 0 0 0 rg BT 36.00 476.10 Td (Leases) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 461.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.99 461.10 Td (February ) Tj ET Q q 0 0 0 rg BT 85.75 461.10 Td (2016, ) Tj ET Q q 0 0 0 rg BT 110.91 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 125.79 461.10 Td (F) Tj ET Q q 0 0 0 rg BT 130.61 461.10 Td (ASB ) Tj ET Q q 0 0 0 rg BT 152.72 461.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 180.38 461.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 219.13 461.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 257.89 461.10 Td (on ) Tj ET Q q 0 0 0 rg BT 270.55 461.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 293.19 461.10 Td (accounting. ) Tj ET Q q 0 0 0 rg BT 342.03 461.10 Td (The ) Tj ET Q q 0 0 0 rg BT 360.24 461.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 398.99 461.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 437.75 461.10 Td (requires ) Tj ET Q q 0 0 0 rg BT 472.61 461.10 Td (the ) Tj ET Q q 0 0 0 rg BT 487.49 461.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 535.69 461.10 Td (of ) Tj ET Q q 0 0 0 rg BT 546.68 461.10 Td (a ) Tj ET Q q 0 0 0 rg BT 553.78 461.10 Td (right-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 449.10 Td (of-use ) Tj ET Q q 0 0 0 rg BT 63.82 449.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 86.08 449.10 Td (and ) Tj ET Q q 0 0 0 rg BT 103.35 449.10 Td (a ) Tj ET Q q 0 0 0 rg BT 110.61 449.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 133.42 449.10 Td (liability) Tj ET Q q 0 0 0 rg BT 163.88 449.10 Td (, ) Tj ET Q q 0 0 0 rg BT 169.21 449.10 Td (initially ) Tj ET Q q 0 0 0 rg BT 203.14 449.10 Td (measured ) Tj ET Q q 0 0 0 rg BT 244.28 449.10 Td (at ) Tj ET Q q 0 0 0 rg BT 254.33 449.10 Td (the ) Tj ET Q q 0 0 0 rg BT 269.37 449.10 Td (present ) Tj ET Q q 0 0 0 rg BT 301.07 449.10 Td (value ) Tj ET Q q 0 0 0 rg BT 325.55 449.10 Td (of ) Tj ET Q q 0 0 0 rg BT 336.71 449.10 Td (future ) Tj ET Q q 0 0 0 rg BT 363.41 449.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 386.22 449.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 427.38 449.10 Td (for ) Tj ET Q q 0 0 0 rg BT 441.86 449.10 Td (leases ) Tj ET Q q 0 0 0 rg BT 468.57 449.10 Td (with ) Tj ET Q q 0 0 0 rg BT 489.17 449.10 Td (a ) Tj ET Q q 0 0 0 rg BT 496.43 449.10 Td (term ) Tj ET Q q 0 0 0 rg BT 517.59 449.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 545.96 449.10 Td (than ) Tj ET Q q 0 0 0 rg BT 566.00 449.10 Td (12 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 437.10 Td (months. ) Tj ET Q q 0 0 0 rg BT 69.78 437.10 Td (The ) Tj ET Q q 0 0 0 rg BT 87.31 437.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 125.38 437.10 Td (is ) Tj ET Q q 0 0 0 rg BT 134.02 437.10 Td (ef) Tj ET Q q 0 0 0 rg BT 141.61 437.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 170.79 437.10 Td (January ) Tj ET Q q 0 0 0 rg BT 203.86 437.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 213.34 437.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 235.32 437.10 Td (with ) Tj ET Q q 0 0 0 rg BT 255.07 437.10 Td (early ) Tj ET Q q 0 0 0 rg BT 277.03 437.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 314.01 437.10 Td (permitted ) Tj ET Q q 0 0 0 rg BT 354.30 437.10 Td (on ) Tj ET Q q 0 0 0 rg BT 366.28 437.10 Td (a ) Tj ET Q q 0 0 0 rg BT 372.69 437.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 410.77 437.10 Td (retrospective ) Tj ET Q q 0 0 0 rg BT 464.39 437.10 Td (approach. ) Tj ET Q q 0 0 0 rg BT 505.37 437.10 Td (W) Tj ET Q q 0 0 0 rg BT 514.01 437.10 Td (e ) Tj ET Q q 0 0 0 rg BT 520.42 437.10 Td (intend ) Tj ET Q q 0 0 0 rg BT 547.39 437.10 Td (to ) Tj ET Q q 0 0 0 rg BT 557.15 437.10 Td (elect ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.39 425.10 Td (available ) Tj ET Q q 0 0 0 rg BT 88.66 425.10 Td (practical ) Tj ET Q q 0 0 0 rg BT 125.25 425.10 Td (expedients ) Tj ET Q q 0 0 0 rg BT 170.19 425.10 Td (on ) Tj ET Q q 0 0 0 rg BT 182.36 425.10 Td (adoption. ) Tj ET Q q 0 0 0 rg BT 221.88 425.10 Td (While ) Tj ET Q q 0 0 0 rg BT 248.49 425.10 Td (our ) Tj ET Q q 0 0 0 rg BT 263.99 425.10 Td (assessment ) Tj ET Q q 0 0 0 rg BT 310.61 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 321.11 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.50 425.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 373.77 425.10 Td (standard ) Tj ET Q q 0 0 0 rg BT 409.82 425.10 Td (remains ) Tj ET Q q 0 0 0 rg BT 443.66 425.10 Td (ongoing, ) Tj ET Q q 0 0 0 rg BT 481.11 425.10 Td (including ) Tj ET Q q 0 0 0 rg BT 521.06 425.10 Td (our ) Tj ET Q q 0 0 0 rg BT 536.56 425.10 Td (continued ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (implementation ) Tj ET Q q 0 0 0 rg BT 101.00 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 111.56 413.10 Td (a ) Tj ET Q q 0 0 0 rg BT 118.23 413.10 Td (leasing ) Tj ET Q q 0 0 0 rg BT 148.78 413.10 Td (software ) Tj ET Q q 0 0 0 rg BT 185.44 413.10 Td (system ) Tj ET Q q 0 0 0 rg BT 215.45 413.10 Td (procured ) Tj ET Q q 0 0 0 rg BT 253.22 413.10 Td (from ) Tj ET Q q 0 0 0 rg BT 274.89 413.10 Td (a ) Tj ET Q q 0 0 0 rg BT 281.56 413.10 Td (3rd ) Tj ET Q q 0 0 0 rg BT 297.12 413.10 Td (party ) Tj ET Q q 0 0 0 rg BT 319.90 413.10 Td (vendor ) Tj ET Q q 0 0 0 rg BT 349.90 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 366.57 413.10 Td (evaluation ) Tj ET Q q 0 0 0 rg BT 410.45 413.10 Td (of ) Tj ET Q q 0 0 0 rg BT 421.01 413.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 458.24 413.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 492.67 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 509.34 413.10 Td (enhancements ) Tj ET Q q 0 0 0 rg BT 568.22 413.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 69.15 401.10 Td (controls, ) Tj ET Q q 0 0 0 rg BT 106.48 401.10 Td (we ) Tj ET Q q 0 0 0 rg BT 120.75 401.10 Td (have ) Tj ET Q q 0 0 0 rg BT 142.24 401.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 195.40 401.10 Td (completed ) Tj ET Q q 0 0 0 rg BT 239.66 401.10 Td (our ) Tj ET Q q 0 0 0 rg BT 255.60 401.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 278.19 401.10 Td (information ) Tj ET Q q 0 0 0 rg BT 328.01 401.10 Td (data ) Tj ET Q q 0 0 0 rg BT 347.28 401.10 Td (gathering ) Tj ET Q q 0 0 0 rg BT 387.65 401.10 Td (and ) Tj ET Q q 0 0 0 rg BT 404.70 401.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 427.30 401.10 Td (data ) Tj ET Q q 0 0 0 rg BT 446.56 401.10 Td (extraction ) Tj ET Q q 0 0 0 rg BT 489.15 401.10 Td (processes ) Tj ET Q q 0 0 0 rg BT 530.08 401.10 Td (and ) Tj ET Q q 0 0 0 rg BT 547.13 401.10 Td (believe ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (our ) Tj ET Q q 0 0 0 rg BT 50.85 389.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 80.13 389.10 Td (implementation ) Tj ET Q q 0 0 0 rg BT 144.41 389.10 Td (ef) Tj ET Q q 0 0 0 rg BT 151.99 389.10 Td (forts ) Tj ET Q q 0 0 0 rg BT 171.84 389.10 Td (remain ) Tj ET Q q 0 0 0 rg BT 201.12 389.10 Td (on ) Tj ET Q q 0 0 0 rg BT 212.64 389.10 Td (schedule. ) Tj ET Q q 0 0 0 rg BT 251.64 389.10 Td (However) Tj ET Q q 0 0 0 rg BT 287.89 389.10 Td (, ) Tj ET Q q 0 0 0 rg BT 291.90 389.10 Td (system ) Tj ET Q q 0 0 0 rg BT 321.20 389.10 Td (readiness ) Tj ET Q q 0 0 0 rg BT 359.92 389.10 Td (remains ) Tj ET Q q 0 0 0 rg BT 393.09 389.10 Td (a ) Tj ET Q q 0 0 0 rg BT 399.05 389.10 Td (critical ) Tj ET Q q 0 0 0 rg BT 428.32 389.10 Td (factor ) Tj ET Q q 0 0 0 rg BT 453.15 389.10 Td (in ) Tj ET Q q 0 0 0 rg BT 462.45 389.10 Td (ensuring ) Tj ET Q q 0 0 0 rg BT 498.40 389.10 Td (successful ) Tj ET Q q 0 0 0 rg BT 541.02 389.10 Td (adoption ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (on ) Tj ET Q q 0 0 0 rg BT 49.12 377.10 Td (January ) Tj ET Q q 0 0 0 rg BT 83.33 377.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 93.95 377.10 Td (2019. ) Tj ET Q q 0 0 0 rg BT 119.34 377.10 Td (The ) Tj ET Q q 0 0 0 rg BT 138.01 377.10 Td (undiscounted ) Tj ET Q q 0 0 0 rg BT 194.45 377.10 Td (value ) Tj ET Q q 0 0 0 rg BT 219.22 377.10 Td (of ) Tj ET Q q 0 0 0 rg BT 230.67 377.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 253.78 377.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 301.34 377.10 Td (is ) Tj ET Q q 0 0 0 rg BT 311.12 377.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.00 377.10 Td ($800 ) Tj ET Q q 0 0 0 rg BT 395.12 377.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.01 377.10 Td ( ) Tj ET Q q 0 0 0 rg BT 427.13 377.10 Td (as ) Tj ET Q q 0 0 0 rg BT 438.58 377.10 Td (of ) Tj ET Q q 0 0 0 rg BT 450.02 377.10 Td (December ) Tj ET Q q 0 0 0 rg BT 494.22 377.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 509.84 377.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 535.46 377.10 Td (consisting ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 75.10 365.10 Td (of ) Tj ET Q q 0 0 0 rg BT 85.33 365.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 115.54 365.10 Td (leases ) Tj ET Q q 0 0 0 rg BT 141.31 365.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 183.73 365.10 Td (for ) Tj ET Q q 0 0 0 rg BT 197.28 365.10 Td (as ) Tj ET Q q 0 0 0 rg BT 207.51 365.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 247.16 365.10 Td (leases. ) Tj ET Q q 0 0 0 rg BT 275.29 365.10 Td (The ) Tj ET Q q 0 0 0 rg BT 292.73 365.10 Td (initial ) Tj ET Q q 0 0 0 rg BT 317.96 365.10 Td (right-of-use ) Tj ET Q q 0 0 0 rg BT 367.05 365.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 388.39 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 404.72 365.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 426.59 365.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 459.59 365.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 495.37 365.10 Td (in ) Tj ET Q q 0 0 0 rg BT 505.04 365.10 Td (the ) Tj ET Q q 0 0 0 rg BT 519.15 365.10 Td (balance ) Tj ET Q q 0 0 0 rg BT 551.58 365.10 Td (sheets ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 58.32 353.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 95.64 353.10 Td (will ) Tj ET Q q 0 0 0 rg BT 113.52 353.10 Td (be ) Tj ET Q q 0 0 0 rg BT 125.28 353.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 155.93 353.10 Td (to ) Tj ET Q q 0 0 0 rg BT 166.03 353.10 Td (several ) Tj ET Q q 0 0 0 rg BT 196.67 353.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 226.20 353.10 Td (including ) Tj ET Q q 0 0 0 rg BT 266.30 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 280.84 353.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 303.15 353.10 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 340.47 353.10 Td (at ) Tj ET Q q 0 0 0 rg BT 350.01 353.10 Td (the ) Tj ET Q q 0 0 0 rg BT 364.55 353.10 Td (date ) Tj ET Q q 0 0 0 rg BT 383.52 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.18 353.10 Td (adoption, ) Tj ET Q q 0 0 0 rg BT 434.00 353.10 Td (selection ) Tj ET Q q 0 0 0 rg BT 471.86 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 482.51 353.10 Td (an ) Tj ET Q q 0 0 0 rg BT 494.28 353.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 542.13 353.10 Td (discount ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 53.95 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 71.35 341.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 122.63 341.10 Td (the ) Tj ET Q q 0 0 0 rg BT 137.81 341.10 Td (fixed ) Tj ET Q q 0 0 0 rg BT 161.31 341.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 184.26 341.10 Td (components ) Tj ET Q q 0 0 0 rg BT 235.55 341.10 Td (and ) Tj ET Q q 0 0 0 rg BT 252.95 341.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 275.90 341.10 Td (renewal ) Tj ET Q q 0 0 0 rg BT 310.50 341.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 342.90 341.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 389.18 341.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 419.34 341.10 Td (to ) Tj ET Q q 0 0 0 rg BT 430.08 341.10 Td (occur) Tj ET Q q 0 0 0 rg BT 451.74 341.10 Td (. ) Tj ET Q q 0 0 0 rg BT 456.98 341.10 Td (The ) Tj ET Q q 0 0 0 rg BT 475.49 341.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 514.55 341.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 553.60 341.10 Td (is ) Tj ET Q q 0 0 0 rg BT 563.23 341.10 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 73.99 329.10 Td (to ) Tj ET Q q 0 0 0 rg BT 84.23 329.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 127.23 329.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 156.90 329.10 Td (the ) Tj ET Q q 0 0 0 rg BT 171.58 329.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 213.24 329.10 Td (s ) Tj ET Q q 0 0 0 rg BT 219.59 329.10 Td (results ) Tj ET Q q 0 0 0 rg BT 248.16 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 258.95 329.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 303.07 329.10 Td (other ) Tj ET Q q 0 0 0 rg BT 326.07 329.10 Td (than ) Tj ET Q q 0 0 0 rg BT 345.75 329.10 Td (the ) Tj ET Q q 0 0 0 rg BT 360.43 329.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 408.43 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 419.22 329.10 Td (the ) Tj ET Q q 0 0 0 rg BT 433.90 329.10 Td (right ) Tj ET Q q 0 0 0 rg BT 455.24 329.10 Td (of ) Tj ET Q q 0 0 0 rg BT 466.03 329.10 Td (use ) Tj ET Q q 0 0 0 rg BT 481.82 329.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 503.72 329.10 Td (and ) Tj ET Q q 0 0 0 rg BT 520.62 329.10 Td (lease ) Tj ET Q q 0 0 0 rg BT 543.06 329.10 Td (liability) Tj ET Q q 0 0 0 rg BT 573.52 329.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 307.7669921875 m 153.4169921875 307.7669921875 l s q 0 0 0 rg BT 36.00 309.10 Td (Goodwill ) Tj ET Q q 0 0 0 rg BT 75.73 309.10 Td (Impairment ) Tj ET Q q 0 0 0 rg BT 124.89 309.10 Td (T) Tj ET Q q 0 0 0 rg BT 129.53 309.10 Td (esting) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 294.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.67 294.10 Td (January ) Tj ET Q q 0 0 0 rg BT 80.11 294.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 104.95 294.10 Td (the ) Tj ET Q q 0 0 0 rg BT 119.51 294.10 Td (F) Tj ET Q q 0 0 0 rg BT 124.33 294.10 Td (ASB ) Tj ET Q q 0 0 0 rg BT 146.12 294.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 173.46 294.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 211.89 294.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 250.33 294.10 Td (that ) Tj ET Q q 0 0 0 rg BT 267.66 294.10 Td (simplifies ) Tj ET Q q 0 0 0 rg BT 309.45 294.10 Td (the ) Tj ET Q q 0 0 0 rg BT 324.00 294.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 371.89 294.10 Td (and ) Tj ET Q q 0 0 0 rg BT 388.67 294.10 Td (measurement ) Tj ET Q q 0 0 0 rg BT 444.32 294.10 Td (of ) Tj ET Q q 0 0 0 rg BT 454.99 294.10 Td (a ) Tj ET Q q 0 0 0 rg BT 461.77 294.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 499.66 294.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 548.10 294.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 566.00 294.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 282.10 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 84.72 282.10 Td (Step ) Tj ET Q q 0 0 0 rg BT 105.67 282.10 Td (2 ) Tj ET Q q 0 0 0 rg BT 113.84 282.10 Td (of ) Tj ET Q q 0 0 0 rg BT 125.34 282.10 Td (the ) Tj ET Q q 0 0 0 rg BT 140.72 282.10 Td (quantitative ) Tj ET Q q 0 0 0 rg BT 191.10 282.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 240.37 282.10 Td (test. ) Tj ET Q q 0 0 0 rg BT 259.23 282.10 Td (As ) Tj ET Q q 0 0 0 rg BT 273.51 282.10 Td (a ) Tj ET Q q 0 0 0 rg BT 281.12 282.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 309.01 282.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 358.28 282.10 Td (char) Tj ET Q q 0 0 0 rg BT 375.30 282.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 391.80 282.10 Td (will ) Tj ET Q q 0 0 0 rg BT 410.53 282.10 Td (be ) Tj ET Q q 0 0 0 rg BT 423.14 282.10 Td (required ) Tj ET Q q 0 0 0 rg BT 459.63 282.10 Td (for ) Tj ET Q q 0 0 0 rg BT 474.46 282.10 Td (the ) Tj ET Q q 0 0 0 rg BT 489.84 282.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 523.01 282.10 Td (by ) Tj ET Q q 0 0 0 rg BT 536.18 282.10 Td (which ) Tj ET Q q 0 0 0 rg BT 563.79 282.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 270.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 74.41 270.10 Td (units ) Tj ET Q q 0 0 0 rg BT 95.61 270.10 Td (carrying ) Tj ET Q q 0 0 0 rg BT 130.67 270.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 162.42 270.10 Td (exceeds ) Tj ET Q q 0 0 0 rg BT 195.82 270.10 Td (its ) Tj ET Q q 0 0 0 rg BT 207.02 270.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 222.65 270.10 Td (value ) Tj ET Q q 0 0 0 rg BT 246.06 270.10 Td (up ) Tj ET Q q 0 0 0 rg BT 257.81 270.10 Td (to ) Tj ET Q q 0 0 0 rg BT 267.34 270.10 Td (the ) Tj ET Q q 0 0 0 rg BT 281.31 270.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 313.05 270.10 Td (of ) Tj ET Q q 0 0 0 rg BT 323.14 270.10 Td (its ) Tj ET Q q 0 0 0 rg BT 334.34 270.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 372.18 270.10 Td (goodwill. ) Tj ET Q q 0 0 0 rg BT 411.86 270.10 Td (The ) Tj ET Q q 0 0 0 rg BT 429.16 270.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 467.00 270.10 Td (is ) Tj ET Q q 0 0 0 rg BT 475.42 270.10 Td (ef) Tj ET Q q 0 0 0 rg BT 483.01 270.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 511.97 270.10 Td (on ) Tj ET Q q 0 0 0 rg BT 523.72 270.10 Td (a ) Tj ET Q q 0 0 0 rg BT 529.91 270.10 Td (prospective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 258.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 58.09 258.10 Td (on ) Tj ET Q q 0 0 0 rg BT 70.18 258.10 Td (January ) Tj ET Q q 0 0 0 rg BT 103.37 258.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 112.96 258.10 Td (2020, ) Tj ET Q q 0 0 0 rg BT 137.55 258.10 Td (with ) Tj ET Q q 0 0 0 rg BT 157.42 258.10 Td (early ) Tj ET Q q 0 0 0 rg BT 179.49 258.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 216.58 258.10 Td (permitted ) Tj ET Q q 0 0 0 rg BT 256.99 258.10 Td (for ) Tj ET Q q 0 0 0 rg BT 270.74 258.10 Td (interim ) Tj ET Q q 0 0 0 rg BT 301.71 258.10 Td (or ) Tj ET Q q 0 0 0 rg BT 312.13 258.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 340.87 258.10 Td (goodwill ) Tj ET Q q 0 0 0 rg BT 378.52 258.10 Td (impairment ) Tj ET Q q 0 0 0 rg BT 426.71 258.10 Td (tests ) Tj ET Q q 0 0 0 rg BT 446.58 258.10 Td (performed ) Tj ET Q q 0 0 0 rg BT 490.31 258.10 Td (after ) Tj ET Q q 0 0 0 rg BT 510.72 258.10 Td (January ) Tj ET Q q 0 0 0 rg BT 543.91 258.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 553.50 258.10 Td (2017. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 246.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 246.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 92.64 246.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 131.23 246.10 Td (is ) Tj ET Q q 0 0 0 rg BT 140.40 246.10 Td (not ) Tj ET Q q 0 0 0 rg BT 155.68 246.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 193.71 246.10 Td (to ) Tj ET Q q 0 0 0 rg BT 203.99 246.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 247.03 246.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 276.74 246.10 Td (the ) Tj ET Q q 0 0 0 rg BT 291.46 246.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 333.12 246.10 Td (s ) Tj ET Q q 0 0 0 rg BT 339.52 246.10 Td (results ) Tj ET Q q 0 0 0 rg BT 368.12 246.10 Td (of ) Tj ET Q q 0 0 0 rg BT 378.95 246.10 Td (operations.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 224.76699218750002 m 254.1298828125 224.76699218750002 l s q 0 0 0 rg BT 36.00 226.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 77.38 226.10 Td (Instruments ) Tj ET Q q 0 0 0 rg BT 127.10 226.10 Td (- ) Tj ET Q q 0 0 0 rg BT 132.93 226.10 Td (Measur) Tj ET Q q 0 0 0 rg BT 163.11 226.10 Td (ement ) Tj ET Q q 0 0 0 rg BT 189.49 226.10 Td (of ) Tj ET Q q 0 0 0 rg BT 199.77 226.10 Td (Cr) Tj ET Q q 0 0 0 rg BT 209.96 226.10 Td (edit ) Tj ET Q q 0 0 0 rg BT 227.46 226.10 Td (Losses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 211.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.43 211.10 Td (June ) Tj ET Q q 0 0 0 rg BT 66.86 211.10 Td (2016, ) Tj ET Q q 0 0 0 rg BT 91.46 211.10 Td (the ) Tj ET Q q 0 0 0 rg BT 105.78 211.10 Td (F) Tj ET Q q 0 0 0 rg BT 110.59 211.10 Td (ASB ) Tj ET Q q 0 0 0 rg BT 132.15 211.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 159.25 211.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 197.44 211.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 235.63 211.10 Td (for ) Tj ET Q q 0 0 0 rg BT 249.39 211.10 Td (the ) Tj ET Q q 0 0 0 rg BT 263.71 211.10 Td (measurement ) Tj ET Q q 0 0 0 rg BT 319.12 211.10 Td (of ) Tj ET Q q 0 0 0 rg BT 329.55 211.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 354.41 211.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 380.40 211.10 Td (on ) Tj ET Q q 0 0 0 rg BT 392.50 211.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 429.58 211.10 Td (instruments. ) Tj ET Q q 0 0 0 rg BT 480.85 211.10 Td (Entities ) Tj ET Q q 0 0 0 rg BT 513.50 211.10 Td (will ) Tj ET Q q 0 0 0 rg BT 531.16 211.10 Td (be ) Tj ET Q q 0 0 0 rg BT 542.69 211.10 Td (required ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 199.10 Td (to ) Tj ET Q q 0 0 0 rg BT 45.92 199.10 Td (use ) Tj ET Q q 0 0 0 rg BT 61.39 199.10 Td (a ) Tj ET Q q 0 0 0 rg BT 67.97 199.10 Td (forward-looking ) Tj ET Q q 0 0 0 rg BT 135.65 199.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 176.11 199.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 193.81 199.10 Td (model. ) Tj ET Q q 0 0 0 rg BT 222.98 199.10 Td (A) Tj ET Q q 0 0 0 rg BT 229.46 199.10 Td (vailable-for) Tj ET Q q 0 0 0 rg BT 275.90 199.10 Td (-sale ) Tj ET Q q 0 0 0 rg BT 296.91 199.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 316.27 199.10 Td (security ) Tj ET Q q 0 0 0 rg BT 350.07 199.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 374.97 199.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 401.01 199.10 Td (will ) Tj ET Q q 0 0 0 rg BT 418.70 199.10 Td (be ) Tj ET Q q 0 0 0 rg BT 430.28 199.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 476.29 199.10 Td (as ) Tj ET Q q 0 0 0 rg BT 486.76 199.10 Td (allowances ) Tj ET Q q 0 0 0 rg BT 533.32 199.10 Td (rather ) Tj ET Q q 0 0 0 rg BT 558.78 199.10 Td (than ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 187.10 Td (a ) Tj ET Q q 0 0 0 rg BT 42.29 187.10 Td (reduction ) Tj ET Q q 0 0 0 rg BT 81.90 187.10 Td (in ) Tj ET Q q 0 0 0 rg BT 91.53 187.10 Td (amortized ) Tj ET Q q 0 0 0 rg BT 133.36 187.10 Td (cost. ) Tj ET Q q 0 0 0 rg BT 153.68 187.10 Td (The ) Tj ET Q q 0 0 0 rg BT 171.08 187.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 209.02 187.10 Td (is ) Tj ET Q q 0 0 0 rg BT 217.54 187.10 Td (ef) Tj ET Q q 0 0 0 rg BT 225.13 187.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 254.18 187.10 Td (January ) Tj ET Q q 0 0 0 rg BT 287.13 187.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 296.48 187.10 Td (2020 ) Tj ET Q q 0 0 0 rg BT 318.33 187.10 Td (with ) Tj ET Q q 0 0 0 rg BT 337.96 187.10 Td (early ) Tj ET Q q 0 0 0 rg BT 359.79 187.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 396.64 187.10 Td (permitted ) Tj ET Q q 0 0 0 rg BT 436.81 187.10 Td (in ) Tj ET Q q 0 0 0 rg BT 446.44 187.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 468.29 187.10 Td (on ) Tj ET Q q 0 0 0 rg BT 480.13 187.10 Td (a ) Tj ET Q q 0 0 0 rg BT 486.42 187.10 Td (modified ) Tj ET Q q 0 0 0 rg BT 524.38 187.10 Td (retrospective ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 175.10 Td (approach. ) Tj ET Q q 0 0 0 rg BT 77.46 175.10 Td (The ) Tj ET Q q 0 0 0 rg BT 95.51 175.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 134.11 175.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 172.70 175.10 Td (is ) Tj ET Q q 0 0 0 rg BT 181.87 175.10 Td (not ) Tj ET Q q 0 0 0 rg BT 197.15 175.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 235.18 175.10 Td (to ) Tj ET Q q 0 0 0 rg BT 245.46 175.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 288.50 175.10 Td (impact ) Tj ET Q q 0 0 0 rg BT 318.21 175.10 Td (the ) Tj ET Q q 0 0 0 rg BT 332.92 175.10 Td (Company’) Tj ET Q q 0 0 0 rg BT 374.59 175.10 Td (s ) Tj ET Q q 0 0 0 rg BT 380.98 175.10 Td (results ) Tj ET Q q 0 0 0 rg BT 409.59 175.10 Td (of ) Tj ET Q q 0 0 0 rg BT 420.42 175.10 Td (operations.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 149.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 149.10 Td (2) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 149.10 Td (. BUSINESS SEGMENT) Tj ET Q q 0 0 0 rg BT 169.18 149.10 Td ( INFORMA) Tj ET Q q 0 0 0 rg BT 219.82 149.10 Td (TION) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 132.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.54 132.10 Td (operates ) Tj ET Q q 0 0 0 rg BT 95.27 132.10 Td (in ) Tj ET Q q 0 0 0 rg BT 105.46 132.10 Td (a ) Tj ET Q q 0 0 0 rg BT 112.32 132.10 Td (single ) Tj ET Q q 0 0 0 rg BT 138.62 132.10 Td (segment ) Tj ET Q q 0 0 0 rg BT 174.36 132.10 Td (engaged ) Tj ET Q q 0 0 0 rg BT 210.09 132.10 Td (in ) Tj ET Q q 0 0 0 rg BT 220.29 132.10 Td (the ) Tj ET Q q 0 0 0 rg BT 234.92 132.10 Td (discovery) Tj ET Q q 0 0 0 rg BT 273.15 132.10 Td (, ) Tj ET Q q 0 0 0 rg BT 278.07 132.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 334.63 132.10 Td (licensing, ) Tj ET Q q 0 0 0 rg BT 375.65 132.10 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 438.88 132.10 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 484.34 132.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 532.87 132.10 Td (and ) Tj ET Q q 0 0 0 rg BT 549.72 132.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 567.68 132.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 120.10 Td (innovative ) Tj ET Q q 0 0 0 rg BT 80.67 120.10 Td (medicines ) Tj ET Q q 0 0 0 rg BT 123.66 120.10 Td (that ) Tj ET Q q 0 0 0 rg BT 141.11 120.10 Td (help ) Tj ET Q q 0 0 0 rg BT 160.79 120.10 Td (patients ) Tj ET Q q 0 0 0 rg BT 194.34 120.10 Td (prevail ) Tj ET Q q 0 0 0 rg BT 224.56 120.10 Td (over ) Tj ET Q q 0 0 0 rg BT 244.79 120.10 Td (serious ) Tj ET Q q 0 0 0 rg BT 275.57 120.10 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 312.75 120.10 Td (A) Tj ET Q q 0 0 0 rg BT 319.42 120.10 Td ( ) Tj ET Q q 0 0 0 rg BT 321.88 120.10 Td (global ) Tj ET Q q 0 0 0 rg BT 349.33 120.10 Td (research ) Tj ET Q q 0 0 0 rg BT 385.09 120.10 Td (and ) Tj ET Q q 0 0 0 rg BT 401.98 120.10 Td (development ) Tj ET Q q 0 0 0 rg BT 456.09 120.10 Td (or) Tj ET Q q 0 0 0 rg BT 464.24 120.10 Td (ganization ) Tj ET Q q 0 0 0 rg BT 508.34 120.10 Td (and ) Tj ET Q q 0 0 0 rg BT 525.24 120.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 554.36 120.10 Td (chain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 108.10 Td (or) Tj ET Q q 0 0 0 rg BT 44.15 108.10 Td (ganization ) Tj ET Q q 0 0 0 rg BT 88.09 108.10 Td (are ) Tj ET Q q 0 0 0 rg BT 102.58 108.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 150.41 108.10 Td (for ) Tj ET Q q 0 0 0 rg BT 164.36 108.10 Td (the ) Tj ET Q q 0 0 0 rg BT 178.86 108.10 Td (discovery) Tj ET Q q 0 0 0 rg BT 217.09 108.10 Td (, ) Tj ET Q q 0 0 0 rg BT 221.88 108.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 278.31 108.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 338.91 108.10 Td (and ) Tj ET Q q 0 0 0 rg BT 355.64 108.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 384.59 108.10 Td (of ) Tj ET Q q 0 0 0 rg BT 395.21 108.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 434.44 108.10 Td (Regional ) Tj ET Q q 0 0 0 rg BT 472.83 108.10 Td (commercial ) Tj ET Q q 0 0 0 rg BT 522.31 108.10 Td (or) Tj ET Q q 0 0 0 rg BT 530.46 108.10 Td (ganizations ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 96.10 Td (market, ) Tj ET Q q 0 0 0 rg BT 69.83 96.10 Td (distribute ) Tj ET Q q 0 0 0 rg BT 111.17 96.10 Td (and ) Tj ET Q q 0 0 0 rg BT 129.17 96.10 Td (sell ) Tj ET Q q 0 0 0 rg BT 146.62 96.10 Td (the ) Tj ET Q q 0 0 0 rg BT 162.40 96.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 202.65 96.10 Td (The ) Tj ET Q q 0 0 0 rg BT 221.76 96.10 Td (business ) Tj ET Q q 0 0 0 rg BT 259.21 96.10 Td (is ) Tj ET Q q 0 0 0 rg BT 269.45 96.10 Td (also ) Tj ET Q q 0 0 0 rg BT 289.12 96.10 Td (supported ) Tj ET Q q 0 0 0 rg BT 332.12 96.10 Td (by ) Tj ET Q q 0 0 0 rg BT 345.69 96.10 Td (global ) Tj ET Q q 0 0 0 rg BT 374.25 96.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 415.57 96.10 Td (staf) Tj ET Q q 0 0 0 rg BT 429.82 96.10 Td (f ) Tj ET Q q 0 0 0 rg BT 436.72 96.10 Td (functions. ) Tj ET Q q 0 0 0 rg BT 480.00 96.10 Td (Segment ) Tj ET Q q 0 0 0 rg BT 518.56 96.10 Td (information ) Tj ET Q q 0 0 0 rg BT 569.34 96.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 84.10 Td (consistent ) Tj ET Q q 0 0 0 rg BT 79.61 84.10 Td (with ) Tj ET Q q 0 0 0 rg BT 101.01 84.10 Td (the ) Tj ET Q q 0 0 0 rg BT 116.84 84.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 155.44 84.10 Td (information ) Tj ET Q q 0 0 0 rg BT 206.27 84.10 Td (regularly ) Tj ET Q q 0 0 0 rg BT 245.99 84.10 Td (reviewed ) Tj ET Q q 0 0 0 rg BT 286.25 84.10 Td (by ) Tj ET Q q 0 0 0 rg BT 299.87 84.10 Td (the ) Tj ET Q q 0 0 0 rg BT 315.70 84.10 Td (chief ) Tj ET Q q 0 0 0 rg BT 339.31 84.10 Td (executive ) Tj ET Q q 0 0 0 rg BT 381.23 84.10 Td (of) Tj ET Q q 0 0 0 rg BT 389.38 84.10 Td (ficer ) Tj ET Q q 0 0 0 rg BT 411.32 84.10 Td (for ) Tj ET Q q 0 0 0 rg BT 426.60 84.10 Td (purposes ) Tj ET Q q 0 0 0 rg BT 465.77 84.10 Td (of ) Tj ET Q q 0 0 0 rg BT 477.71 84.10 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 522.98 84.10 Td (performance, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 72.10 Td (allocating ) Tj ET Q q 0 0 0 rg BT 77.93 72.10 Td (resources, ) Tj ET Q q 0 0 0 rg BT 120.69 72.10 Td (setting ) Tj ET Q q 0 0 0 rg BT 149.85 72.10 Td (incentive ) Tj ET Q q 0 0 0 rg BT 189.00 72.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 247.04 72.10 Td (tar) Tj ET Q q 0 0 0 rg BT 257.41 72.10 Td (gets, ) Tj ET Q q 0 0 0 rg BT 278.52 72.10 Td (and ) Tj ET Q q 0 0 0 rg BT 295.46 72.10 Td (planning ) Tj ET Q q 0 0 0 rg BT 332.95 72.10 Td (and ) Tj ET Q q 0 0 0 rg BT 349.89 72.10 Td (forecasting ) Tj ET Q q 0 0 0 rg BT 396.82 72.10 Td (future ) Tj ET Q q 0 0 0 rg BT 423.19 72.10 Td (periods.) Tj ET Q endstream endobj 131 0 obj <> endobj 132 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Products ) Tj ET Q q 0 0 0 rg BT 72.61 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 86.43 749.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 104.72 749.10 Td (principally ) Tj ET Q q 0 0 0 rg BT 149.65 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 159.04 749.10 Td (wholesalers, ) Tj ET Q q 0 0 0 rg BT 210.37 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 226.42 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 235.81 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 241.86 749.10 Td (lesser ) Tj ET Q q 0 0 0 rg BT 266.24 749.10 Td (extent, ) Tj ET Q q 0 0 0 rg BT 294.79 749.10 Td (directly ) Tj ET Q q 0 0 0 rg BT 326.95 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 336.34 749.10 Td (distributors, ) Tj ET Q q 0 0 0 rg BT 386.01 749.10 Td (retailers, ) Tj ET Q q 0 0 0 rg BT 422.33 749.10 Td (hospitals, ) Tj ET Q q 0 0 0 rg BT 462.00 749.10 Td (clinics, ) Tj ET Q q 0 0 0 rg BT 492.21 749.10 Td (government ) Tj ET Q q 0 0 0 rg BT 541.59 749.10 Td (agencies ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.47 737.10 Td (pharmacies. ) Tj ET Q q 0 0 0 rg BT 102.54 737.10 Td (Gross ) Tj ET Q q 0 0 0 rg BT 127.91 737.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 165.48 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 175.29 737.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 189.54 737.10 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 209.53 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 211.56 737.10 Td (lar) Tj ET Q q 0 0 0 rg BT 221.93 737.10 Td (gest ) Tj ET Q q 0 0 0 rg BT 240.07 737.10 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 303.18 737.10 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 352.42 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 362.23 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 376.48 737.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 396.30 737.10 Td (as ) Tj ET Q q 0 0 0 rg BT 406.66 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 413.13 737.10 Td (percentage ) Tj ET Q q 0 0 0 rg BT 458.47 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 468.83 737.10 Td (global ) Tj ET Q q 0 0 0 rg BT 495.86 737.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 519.01 737.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 556.58 737.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (as ) Tj ET Q q 0 0 0 rg BT 46.83 725.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 701.60 363.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 399.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 403.50 701.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 458.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 701.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 701.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 675.60 363.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 399.50 675.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 403.50 675.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 458.50 675.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 675.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 675.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 675.60 55.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 701.6 m 458.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 701.6 m 517.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 701.6 m 576.5 701.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 422.50 705.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 481.50 705.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 540.50 705.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 692.17 Td (McKesson Corporation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 692.17 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 449.65 692.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 692.17 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 692.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 692.17 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 692.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 679.17 Td (AmerisourceBer) Tj ET Q q 0 0 0 rg BT 104.99 679.17 Td (gen Corporation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 679.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 449.65 679.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 679.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 679.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 679.17 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 679.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 666.17 Td (Cardinal Health, Inc.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 666.17 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 449.65 666.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 666.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 666.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 666.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 666.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 642.10 Td (Selected geographic area information was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 605.60 245.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 281.50 605.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 605.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 340.50 605.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 344.50 605.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 399.50 605.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 403.50 605.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 458.50 605.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 605.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 605.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 605.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 579.60 245.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 281.50 579.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 579.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 340.50 579.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 344.50 579.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 399.50 579.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 403.50 579.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 458.50 579.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 579.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 579.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 579.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 553.60 245.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 281.50 553.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 285.50 553.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 340.50 553.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 344.50 553.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 399.50 553.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 403.50 553.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 458.50 553.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 553.60 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 517.50 553.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 553.60 55.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 618.6 m 340.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 340.5 618.6 m 344.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 618.6 m 399.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 399.5 618.6 m 403.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 618.6 m 458.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 618.6 m 517.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 517.5 618.6 m 521.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 618.6 m 576.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 605.6 m 340.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 605.6 m 399.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 605.6 m 458.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 605.6 m 517.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 605.6 m 576.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 605.6 m 340.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 605.6 m 399.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 605.6 m 458.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 605.6 m 576.5 605.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 553.6 m 340.5 553.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 553.6 m 399.5 553.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 553.6 m 458.5 553.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 553.6 m 517.5 553.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 553.6 m 576.5 553.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 541.6 m 340.5 541.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 285.5 539.6 m 340.5 539.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 541.6 m 399.5 541.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 344.5 539.6 m 399.5 539.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 541.6 m 458.5 541.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 403.5 539.6 m 458.5 539.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 541.6 m 517.5 541.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 539.6 m 517.5 539.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 541.6 m 576.5 541.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 521.5 539.6 m 576.5 539.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 622.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 355.25 622.83 Td (Revenues) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 465.25 622.83 Td (Pr) Tj ET Q q 0 0 0 rg BT 473.62 622.83 Td (operty) Tj ET Q q 0 0 0 rg BT 495.54 622.83 Td (, Plant and Equipment) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 609.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 304.50 609.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 363.50 609.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 422.50 609.83 Td (2015) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 481.50 609.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 540.50 609.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 596.17 Td (United States) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.00 596.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.15 596.17 Td (1) Tj ET Q q 0 0 0 rg BT 314.15 596.17 Td (1,358) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.00 596.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 368.15 596.17 Td (10,720) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.00 596.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.15 596.17 Td (8,188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.00 596.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 596.17 Td (3,617) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 596.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 596.17 Td (3,865) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 583.17 Td (Europe) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.15 583.17 Td (4,988) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.15 583.17 Td (4,215) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.15 583.17 Td (3,491) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 583.17 Td (1,266) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 583.17 Td (1,003) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 570.17 Td (Rest of the ) Tj ET Q q 0 0 0 rg BT 84.64 570.17 Td (W) Tj ET Q q 0 0 0 rg BT 93.28 570.17 Td (orld) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 109.39 574.70 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.15 570.17 Td (3,877) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.15 570.17 Td (3,964) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.15 570.17 Td (4,142) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 570.17 Td (1) Tj ET Q q 0 0 0 rg BT 503.65 570.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 570.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 570.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 557.17 Td (Other) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 61.77 561.70 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 69.35 557.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.65 557.17 Td (553) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 380.65 557.17 Td (528) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 557.17 Td (739) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.65 557.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 557.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 544.17 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 544.17 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.00 544.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.15 544.17 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.00 544.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 368.15 544.17 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.00 544.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.15 544.17 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.00 544.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.15 544.17 Td (5,001) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.00 544.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 544.17 Td (4,980) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 528.50 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 54.00 528.50 Td (Includes Japan which represented ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 163.73 528.50 Td (7%) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 174.40 528.50 Td (, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 178.40 528.50 Td (7%) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 189.06 528.50 Td ( and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 204.61 528.50 Td (10%) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 219.28 528.50 Td ( of total revenues in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 284.81 528.50 Td (2017) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 300.81 528.50 Td (, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 304.81 528.50 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 320.81 528.50 Td ( and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 336.36 528.50 Td (2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 352.36 528.50 Td (, respectively) Tj ET Q q 0 0 0 rg BT 394.49 528.50 Td (. ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 518.90 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 54.00 518.90 Td (Other ) Tj ET Q q 0 0 0 rg BT 74.21 518.90 Td (revenues ) Tj ET Q q 0 0 0 rg BT 104.64 518.90 Td (include ) Tj ET Q q 0 0 0 rg BT 130.19 518.90 Td (royalties ) Tj ET Q q 0 0 0 rg BT 159.74 518.90 Td (and ) Tj ET Q q 0 0 0 rg BT 173.29 518.90 Td (alliance-related ) Tj ET Q q 0 0 0 rg BT 224.59 518.90 Td (revenues ) Tj ET Q q 0 0 0 rg BT 255.02 518.90 Td (for ) Tj ET Q q 0 0 0 rg BT 266.34 518.90 Td (products ) Tj ET Q q 0 0 0 rg BT 295.89 518.90 Td (not ) Tj ET Q q 0 0 0 rg BT 308.12 518.90 Td (sold ) Tj ET Q q 0 0 0 rg BT 323.45 518.90 Td (by ) Tj ET Q q 0 0 0 rg BT 333.45 518.90 Td (our ) Tj ET Q q 0 0 0 rg BT 346.12 518.90 Td (regional ) Tj ET Q q 0 0 0 rg BT 374.33 518.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 414.09 518.90 Td (or) Tj ET Q q 0 0 0 rg BT 420.61 518.90 Td (ganizations.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.90 Td (Product revenues and the composition of total revenues were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 461.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 461.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 461.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 461.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 461.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 461.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 461.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 435.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 435.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 435.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 435.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 435.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 435.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 435.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 409.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 409.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 409.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 409.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 409.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 409.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 409.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 383.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 383.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 383.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 383.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 383.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 383.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 383.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 357.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 357.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 357.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 357.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 357.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 357.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 357.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 331.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 331.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 331.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 331.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 331.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 331.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 331.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 305.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 305.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 305.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 305.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 305.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 305.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 305.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 279.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 279.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 279.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 279.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 279.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 279.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 279.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 253.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 253.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 253.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 253.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 253.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 253.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 253.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 227.40 303.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 339.50 227.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 343.50 227.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 418.50 227.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 227.40 75.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 227.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 227.40 75.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 474.4 m 418.5 474.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 418.5 474.4 m 422.5 474.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 474.4 m 497.5 474.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 474.4 m 501.5 474.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 474.4 m 576.5 474.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 461.4 m 418.5 461.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 461.4 m 497.5 461.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 461.4 m 576.5 461.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 292.4 m 418.5 292.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 280.4 m 418.5 280.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 278.4 m 418.5 278.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 292.4 m 497.5 292.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 280.4 m 497.5 280.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 278.4 m 497.5 278.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 292.4 m 576.5 292.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 280.4 m 576.5 280.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 278.4 m 576.5 278.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 227.39999999999998 m 418.5 227.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 215.39999999999998 m 418.5 215.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 343.5 213.39999999999998 m 418.5 213.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 227.39999999999998 m 497.5 227.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 215.39999999999998 m 497.5 215.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 422.5 213.39999999999998 m 497.5 213.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 227.39999999999998 m 576.5 227.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 215.39999999999998 m 576.5 215.39999999999998 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 213.39999999999998 m 576.5 213.39999999999998 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 478.65 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 415.20 478.63 Td (Y) Tj ET Q q 0 0 0 rg BT 420.53 478.63 Td (ear) Tj ET Q q 0 0 0 rg BT 431.12 478.63 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 491.85 478.63 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 465.65 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 372.50 465.63 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 451.50 465.63 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 530.50 465.63 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 452.13 Td (Prioritized Brands) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 438.96 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.00 438.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 438.97 Td (4,948) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.00 438.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 438.97 Td (3,774) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 438.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 438.97 Td (942) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 425.96 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 425.97 Td (4,872) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 425.97 Td (3,343) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 425.97 Td (1,860) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 412.96 Td (Or) Tj ET Q q 0 0 0 rg BT 49.93 412.96 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 412.97 Td (2,479) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 412.97 Td (2,265) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 412.97 Td (1,885) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 399.96 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 399.97 Td (2,005) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 399.97 Td (1,824) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 399.97 Td (1,620) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 386.96 Td (Y) Tj ET Q q 0 0 0 rg BT 44.10 386.96 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 386.97 Td (1,244) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 386.97 Td (1,053) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 386.97 Td (1,126) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 373.96 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.65 373.97 Td (231) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 373.97 Td (150) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 373.97 Td (3) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 361.13 Td (Established Brands) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 347.96 Td (Baraclude) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 347.97 Td (1,052) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 347.97 Td (1,192) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 347.97 Td (1,312) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 334.96 Td (Sustiva Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.65 334.97 Td (729) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 334.97 Td (1,065) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 334.97 Td (1,252) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 39.00 321.96 Td (Reyataz Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.65 321.97 Td (698) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 321.97 Td (912) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 321.97 Td (1,139) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 308.97 Td (Hepatitis C Franchise) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.65 308.97 Td (406) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 308.97 Td (1,578) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 308.97 Td (1,603) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 295.97 Td (Other Brands) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 295.97 Td (2,1) Tj ET Q q 0 0 0 rg BT 404.65 295.97 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 295.97 Td (2,271) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 295.97 Td (3,818) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 282.97 Td (T) Tj ET Q q 0 0 0 rg BT 56.76 282.97 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.00 282.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.15 282.97 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.00 282.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 282.97 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 282.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 282.97 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 256.97 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.00 256.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.15 256.97 Td (19,258) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.00 256.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 256.97 Td (17,702) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 256.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 256.97 Td (14,045) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 243.97 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.15 243.97 Td (1,294) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.15 243.97 Td (1,629) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 243.97 Td (2,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 230.97 Td (Other revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.65 230.97 Td (224) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 230.97 Td (96) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 230.97 Td (107) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 217.97 Td (T) Tj ET Q q 0 0 0 rg BT 56.41 217.97 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.00 217.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.15 217.97 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.00 217.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 217.97 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.00 217.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 217.97 Td (16,560) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 188.90 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 188.90 Td (3) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 188.90 Td (. ) Tj ET Q q 0 0 0 rg BT 67.94 188.90 Td (ALLIANCES) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 164.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.33 164.90 Td (enters ) Tj ET Q q 0 0 0 rg BT 85.42 164.90 Td (into ) Tj ET Q q 0 0 0 rg BT 103.19 164.90 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 158.16 164.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 214.23 164.90 Td (with ) Tj ET Q q 0 0 0 rg BT 234.22 164.90 Td (third ) Tj ET Q q 0 0 0 rg BT 255.32 164.90 Td (parties ) Tj ET Q q 0 0 0 rg BT 284.19 164.90 Td (for ) Tj ET Q q 0 0 0 rg BT 298.06 164.90 Td (the ) Tj ET Q q 0 0 0 rg BT 312.48 164.90 Td (development ) Tj ET Q q 0 0 0 rg BT 366.35 164.90 Td (and ) Tj ET Q q 0 0 0 rg BT 383.00 164.90 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 459.62 164.90 Td (of ) Tj ET Q q 0 0 0 rg BT 470.16 164.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 499.57 164.90 Td (products. ) Tj ET Q q 0 0 0 rg BT 538.23 164.90 Td (Although ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 152.90 Td (each ) Tj ET Q q 0 0 0 rg BT 57.37 152.90 Td (of ) Tj ET Q q 0 0 0 rg BT 68.75 152.90 Td (these ) Tj ET Q q 0 0 0 rg BT 92.35 152.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 149.26 152.90 Td (is ) Tj ET Q q 0 0 0 rg BT 158.98 152.90 Td (unique ) Tj ET Q q 0 0 0 rg BT 189.25 152.90 Td (in ) Tj ET Q q 0 0 0 rg BT 200.08 152.90 Td (nature, ) Tj ET Q q 0 0 0 rg BT 230.62 152.90 Td (both ) Tj ET Q q 0 0 0 rg BT 251.45 152.90 Td (parties ) Tj ET Q q 0 0 0 rg BT 281.16 152.90 Td (are ) Tj ET Q q 0 0 0 rg BT 296.42 152.90 Td (active ) Tj ET Q q 0 0 0 rg BT 323.34 152.90 Td (participants ) Tj ET Q q 0 0 0 rg BT 373.04 152.90 Td (in ) Tj ET Q q 0 0 0 rg BT 383.87 152.90 Td (the ) Tj ET Q q 0 0 0 rg BT 399.14 152.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 439.96 152.90 Td (activities ) Tj ET Q q 0 0 0 rg BT 479.11 152.90 Td (of ) Tj ET Q q 0 0 0 rg BT 490.49 152.90 Td (the ) Tj ET Q q 0 0 0 rg BT 505.76 152.90 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 561.57 152.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 140.90 Td (exposed ) Tj ET Q q 0 0 0 rg BT 71.42 140.90 Td (to ) Tj ET Q q 0 0 0 rg BT 81.84 140.90 Td (significant ) Tj ET Q q 0 0 0 rg BT 126.70 140.90 Td (risks ) Tj ET Q q 0 0 0 rg BT 148.24 140.90 Td (and ) Tj ET Q q 0 0 0 rg BT 165.33 140.90 Td (rewards ) Tj ET Q q 0 0 0 rg BT 199.63 140.90 Td (depending ) Tj ET Q q 0 0 0 rg BT 243.93 140.90 Td (on ) Tj ET Q q 0 0 0 rg BT 256.58 140.90 Td (the ) Tj ET Q q 0 0 0 rg BT 271.44 140.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 321.29 140.90 Td (success ) Tj ET Q q 0 0 0 rg BT 353.93 140.90 Td (of ) Tj ET Q q 0 0 0 rg BT 364.90 140.90 Td (the ) Tj ET Q q 0 0 0 rg BT 379.77 140.90 Td (activities. ) Tj ET Q q 0 0 0 rg BT 421.02 140.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 444.79 140.90 Td (may ) Tj ET Q q 0 0 0 rg BT 464.65 140.90 Td (either ) Tj ET Q q 0 0 0 rg BT 490.06 140.90 Td (in-license ) Tj ET Q q 0 0 0 rg BT 531.58 140.90 Td (intellectual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 128.90 Td (property ) Tj ET Q q 0 0 0 rg BT 72.78 128.90 Td (owned ) Tj ET Q q 0 0 0 rg BT 102.35 128.90 Td (by ) Tj ET Q q 0 0 0 rg BT 115.25 128.90 Td (the ) Tj ET Q q 0 0 0 rg BT 130.38 128.90 Td (other ) Tj ET Q q 0 0 0 rg BT 153.83 128.90 Td (party ) Tj ET Q q 0 0 0 rg BT 177.28 128.90 Td (or ) Tj ET Q q 0 0 0 rg BT 188.51 128.90 Td (out-license ) Tj ET Q q 0 0 0 rg BT 235.29 128.90 Td (its ) Tj ET Q q 0 0 0 rg BT 247.65 128.90 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 294.97 128.90 Td (property ) Tj ET Q q 0 0 0 rg BT 331.76 128.90 Td (to ) Tj ET Q q 0 0 0 rg BT 342.44 128.90 Td (the ) Tj ET Q q 0 0 0 rg BT 357.56 128.90 Td (other ) Tj ET Q q 0 0 0 rg BT 381.01 128.90 Td (party) Tj ET Q q 0 0 0 rg BT 400.91 128.90 Td (. ) Tj ET Q q 0 0 0 rg BT 406.11 128.90 Td (These ) Tj ET Q q 0 0 0 rg BT 432.89 128.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 489.66 128.90 Td (also ) Tj ET Q q 0 0 0 rg BT 508.67 128.90 Td (typically ) Tj ET Q q 0 0 0 rg BT 546.57 128.90 Td (include ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 116.90 Td (research, ) Tj ET Q q 0 0 0 rg BT 75.02 116.90 Td (development, ) Tj ET Q q 0 0 0 rg BT 132.38 116.90 Td (manufacturing, ) Tj ET Q q 0 0 0 rg BT 196.40 116.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 225.15 116.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 275.56 116.90 Td (activities ) Tj ET Q q 0 0 0 rg BT 314.87 116.90 Td (and ) Tj ET Q q 0 0 0 rg BT 332.51 116.90 Td (can ) Tj ET Q q 0 0 0 rg BT 349.60 116.90 Td (cover ) Tj ET Q q 0 0 0 rg BT 375.02 116.90 Td (a ) Tj ET Q q 0 0 0 rg BT 382.67 116.90 Td (single ) Tj ET Q q 0 0 0 rg BT 409.76 116.90 Td (investigational ) Tj ET Q q 0 0 0 rg BT 471.85 116.90 Td (compound ) Tj ET Q q 0 0 0 rg BT 517.27 116.90 Td (or ) Tj ET Q q 0 0 0 rg BT 528.81 116.90 Td (commercial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 104.90 Td (product ) Tj ET Q q 0 0 0 rg BT 69.51 104.90 Td (or ) Tj ET Q q 0 0 0 rg BT 80.81 104.90 Td (multiple ) Tj ET Q q 0 0 0 rg BT 117.11 104.90 Td (compounds ) Tj ET Q q 0 0 0 rg BT 166.18 104.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 194.69 104.90 Td (products ) Tj ET Q q 0 0 0 rg BT 232.10 104.90 Td (in ) Tj ET Q q 0 0 0 rg BT 242.84 104.90 Td (various ) Tj ET Q q 0 0 0 rg BT 275.25 104.90 Td (life ) Tj ET Q q 0 0 0 rg BT 291.54 104.90 Td (cycle ) Tj ET Q q 0 0 0 rg BT 315.60 104.90 Td (stages. ) Tj ET Q q 0 0 0 rg BT 345.29 104.90 Td (The ) Tj ET Q q 0 0 0 rg BT 363.80 104.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 389.55 104.90 Td (and ) Tj ET Q q 0 0 0 rg BT 406.95 104.90 Td (obligations ) Tj ET Q q 0 0 0 rg BT 454.36 104.90 Td (of ) Tj ET Q q 0 0 0 rg BT 465.66 104.90 Td (the ) Tj ET Q q 0 0 0 rg BT 480.84 104.90 Td (parties ) Tj ET Q q 0 0 0 rg BT 510.46 104.90 Td (can ) Tj ET Q q 0 0 0 rg BT 527.31 104.90 Td (be ) Tj ET Q q 0 0 0 rg BT 539.71 104.90 Td (global ) Tj ET Q q 0 0 0 rg BT 567.67 104.90 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 92.90 Td (limited ) Tj ET Q q 0 0 0 rg BT 66.99 92.90 Td (to ) Tj ET Q q 0 0 0 rg BT 77.44 92.90 Td (geographic ) Tj ET Q q 0 0 0 rg BT 124.52 92.90 Td (regions. ) Tj ET Q q 0 0 0 rg BT 158.93 92.90 Td (W) Tj ET Q q 0 0 0 rg BT 167.57 92.90 Td (e ) Tj ET Q q 0 0 0 rg BT 174.67 92.90 Td (refer ) Tj ET Q q 0 0 0 rg BT 196.20 92.90 Td (to ) Tj ET Q q 0 0 0 rg BT 206.65 92.90 Td (these ) Tj ET Q q 0 0 0 rg BT 229.86 92.90 Td (collaborations ) Tj ET Q q 0 0 0 rg BT 289.17 92.90 Td (as ) Tj ET Q q 0 0 0 rg BT 300.16 92.90 Td (alliances ) Tj ET Q q 0 0 0 rg BT 337.81 92.90 Td (and ) Tj ET Q q 0 0 0 rg BT 354.91 92.90 Td (our ) Tj ET Q q 0 0 0 rg BT 370.90 92.90 Td (partners ) Tj ET Q q 0 0 0 rg BT 405.77 92.90 Td (as ) Tj ET Q q 0 0 0 rg BT 416.77 92.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 450.52 92.90 Td (partners. ) Tj ET Q q 0 0 0 rg BT 487.89 92.90 Td (Products ) Tj ET Q q 0 0 0 rg BT 525.55 92.90 Td (sold ) Tj ET Q q 0 0 0 rg BT 544.89 92.90 Td (through ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 80.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 69.30 80.90 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 125.37 80.90 Td (in ) Tj ET Q q 0 0 0 rg BT 135.36 80.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 164.77 80.90 Td (markets ) Tj ET Q q 0 0 0 rg BT 198.63 80.90 Td (include ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 230.28 80.90 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.72 80.90 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 264.43 80.90 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.76 80.90 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 297.47 80.90 Td (Or) Tj ET Q q 0 0 0 rg BT 308.21 80.90 Td (encia, ) Tj ET Q q 0 0 0 rg BT 334.58 80.90 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.56 80.90 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 369.27 80.90 Td (Y) Tj ET Q q 0 0 0 rg BT 373.92 80.90 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 396.12 80.90 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 400.83 80.90 Td (Empliciti) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.49 80.90 Td (, ) Tj ET Q q 0 0 0 rg BT 442.20 80.90 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 458.85 80.90 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.74 80.90 Td ( ) Tj ET Q q 0 0 0 rg BT 489.95 80.90 Td (\() Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 493.28 80.90 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 526.61 80.90 Td (\) ) Tj ET Q q 0 0 0 rg BT 532.15 80.90 Td (and ) Tj ET Q q 0 0 0 rg BT 548.80 80.90 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 68.90 Td (other ) Tj ET Q q 0 0 0 rg BT 59.05 68.90 Td (brands.) Tj ET Q endstream endobj 133 0 obj <> endobj 134 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Payments ) Tj ET Q q 0 0 0 rg BT 77.50 749.10 Td (between ) Tj ET Q q 0 0 0 rg BT 113.43 749.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 147.14 749.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 181.96 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 196.78 749.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 239.93 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 254.20 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 271.25 749.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 312.18 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 322.58 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 337.41 749.10 Td (results ) Tj ET Q q 0 0 0 rg BT 366.13 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 377.08 749.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 421.35 749.10 Td (after ) Tj ET Q q 0 0 0 rg BT 442.28 749.10 Td (considering ) Tj ET Q q 0 0 0 rg BT 491.55 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 506.38 749.10 Td (specific ) Tj ET Q q 0 0 0 rg BT 540.09 749.10 Td (nature ) Tj ET Q q 0 0 0 rg BT 567.69 749.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.81 737.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 87.84 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 104.88 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 119.69 737.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 165.61 737.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 204.31 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 214.68 737.10 Td (which ) Tj ET Q q 0 0 0 rg BT 241.72 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 256.53 737.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 297.46 737.10 Td (relate. ) Tj ET Q q 0 0 0 rg BT 324.75 737.10 Td (Multiple ) Tj ET Q q 0 0 0 rg BT 361.79 737.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 395.48 737.10 Td (activities, ) Tj ET Q q 0 0 0 rg BT 436.67 737.10 Td (including ) Tj ET Q q 0 0 0 rg BT 477.04 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 491.86 737.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 524.99 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 535.92 737.10 Td (rights, ) Tj ET Q q 0 0 0 rg BT 563.79 737.10 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (only ) Tj ET Q q 0 0 0 rg BT 57.25 725.10 Td (separated ) Tj ET Q q 0 0 0 rg BT 98.48 725.10 Td (into ) Tj ET Q q 0 0 0 rg BT 117.51 725.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 161.54 725.10 Td (units ) Tj ET Q q 0 0 0 rg BT 184.46 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 196.26 725.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 243.61 725.10 Td (if ) Tj ET Q q 0 0 0 rg BT 253.19 725.10 Td (they ) Tj ET Q q 0 0 0 rg BT 273.88 725.10 Td (have ) Tj ET Q q 0 0 0 rg BT 296.23 725.10 Td (standalone ) Tj ET Q q 0 0 0 rg BT 342.47 725.10 Td (value ) Tj ET Q q 0 0 0 rg BT 367.60 725.10 Td (from ) Tj ET Q q 0 0 0 rg BT 390.51 725.10 Td (other ) Tj ET Q q 0 0 0 rg BT 414.54 725.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 454.11 725.10 Td (that ) Tj ET Q q 0 0 0 rg BT 472.58 725.10 Td (occur ) Tj ET Q q 0 0 0 rg BT 498.26 725.10 Td (over ) Tj ET Q q 0 0 0 rg BT 519.50 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 535.19 725.10 Td (life ) Tj ET Q q 0 0 0 rg BT 551.99 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 563.80 725.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 94.75 713.10 Td (In ) Tj ET Q q 0 0 0 rg BT 105.46 713.10 Td (these ) Tj ET Q q 0 0 0 rg BT 128.39 713.10 Td (situations, ) Tj ET Q q 0 0 0 rg BT 171.61 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 186.21 713.10 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 238.57 713.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 294.82 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 303.88 713.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 342.35 713.10 Td (to ) Tj ET Q q 0 0 0 rg BT 352.51 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 367.11 713.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 405.60 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 416.31 713.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 441.47 713.10 Td (on ) Tj ET Q q 0 0 0 rg BT 453.86 713.10 Td (a ) Tj ET Q q 0 0 0 rg BT 460.68 713.10 Td (relative ) Tj ET Q q 0 0 0 rg BT 493.05 713.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 522.10 713.10 Td (price ) Tj ET Q q 0 0 0 rg BT 544.47 713.10 Td (basis. ) Tj ET Q q 0 0 0 rg BT 569.35 713.10 Td (If ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (multiple ) Tj ET Q q 0 0 0 rg BT 71.83 701.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 105.42 701.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 144.02 701.10 Td (or ) Tj ET Q q 0 0 0 rg BT 154.85 701.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 180.13 701.10 Td (do ) Tj ET Q q 0 0 0 rg BT 192.63 701.10 Td (not ) Tj ET Q q 0 0 0 rg BT 207.90 701.10 Td (have ) Tj ET Q q 0 0 0 rg BT 229.28 701.10 Td (standalone ) Tj ET Q q 0 0 0 rg BT 274.54 701.10 Td (value, ) Tj ET Q q 0 0 0 rg BT 301.20 701.10 Td (they ) Tj ET Q q 0 0 0 rg BT 320.92 701.10 Td (are ) Tj ET Q q 0 0 0 rg BT 335.62 701.10 Td (combined ) Tj ET Q q 0 0 0 rg BT 377.56 701.10 Td (into ) Tj ET Q q 0 0 0 rg BT 395.61 701.10 Td (a ) Tj ET Q q 0 0 0 rg BT 402.55 701.10 Td (single ) Tj ET Q q 0 0 0 rg BT 428.94 701.10 Td (unit ) Tj ET Q q 0 0 0 rg BT 447.00 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 457.83 701.10 Td (accounting.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (The most common activities between BMS and its alliance partners are presented in results of operations as follows:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 657.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 657.90 Td (When ) Tj ET Q q 0 0 0 rg BT 98.94 657.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 123.12 657.90 Td (is ) Tj ET Q q 0 0 0 rg BT 132.84 657.90 Td (the ) Tj ET Q q 0 0 0 rg BT 148.12 657.90 Td (principal ) Tj ET Q q 0 0 0 rg BT 186.72 657.90 Td (in ) Tj ET Q q 0 0 0 rg BT 197.56 657.90 Td (the ) Tj ET Q q 0 0 0 rg BT 212.83 657.90 Td (end ) Tj ET Q q 0 0 0 rg BT 230.33 657.90 Td (customer ) Tj ET Q q 0 0 0 rg BT 270.04 657.90 Td (sale, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 291.15 657.90 Td (100%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.48 657.90 Td ( ) Tj ET Q q 0 0 0 rg BT 317.53 657.90 Td (of ) Tj ET Q q 0 0 0 rg BT 328.92 657.90 Td (product ) Tj ET Q q 0 0 0 rg BT 362.53 657.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 385.02 657.90 Td (are ) Tj ET Q q 0 0 0 rg BT 400.29 657.90 Td (included ) Tj ET Q q 0 0 0 rg BT 437.78 657.90 Td (in ) Tj ET Q q 0 0 0 rg BT 448.62 657.90 Td (net ) Tj ET Q q 0 0 0 rg BT 463.89 657.90 Td (product ) Tj ET Q q 0 0 0 rg BT 497.50 657.90 Td (sales. ) Tj ET Q q 0 0 0 rg BT 522.27 657.90 Td (When ) Tj ET Q q 0 0 0 rg BT 549.21 657.90 Td (BMS's ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 645.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 105.33 645.90 Td (partner ) Tj ET Q q 0 0 0 rg BT 135.89 645.90 Td (is ) Tj ET Q q 0 0 0 rg BT 144.81 645.90 Td (the ) Tj ET Q q 0 0 0 rg BT 159.27 645.90 Td (principal ) Tj ET Q q 0 0 0 rg BT 197.06 645.90 Td (in ) Tj ET Q q 0 0 0 rg BT 207.08 645.90 Td (the ) Tj ET Q q 0 0 0 rg BT 221.54 645.90 Td (end ) Tj ET Q q 0 0 0 rg BT 238.23 645.90 Td (customer ) Tj ET Q q 0 0 0 rg BT 277.13 645.90 Td (sale, ) Tj ET Q q 0 0 0 rg BT 297.42 645.90 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 326.48 645.90 Td (contractual ) Tj ET Q q 0 0 0 rg BT 373.15 645.90 Td (share ) Tj ET Q q 0 0 0 rg BT 396.49 645.90 Td (of ) Tj ET Q q 0 0 0 rg BT 407.06 645.90 Td (the ) Tj ET Q q 0 0 0 rg BT 421.53 645.90 Td (third-party ) Tj ET Q q 0 0 0 rg BT 466.54 645.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 488.22 645.90 Td (and/or ) Tj ET Q q 0 0 0 rg BT 516.01 645.90 Td (royalty ) Tj ET Q q 0 0 0 rg BT 546.58 645.90 Td (income ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 633.90 Td (are ) Tj ET Q q 0 0 0 rg BT 87.52 633.90 Td (included ) Tj ET Q q 0 0 0 rg BT 125.27 633.90 Td (in ) Tj ET Q q 0 0 0 rg BT 136.36 633.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 170.76 633.90 Td (revenue ) Tj ET Q q 0 0 0 rg BT 205.72 633.90 Td (as ) Tj ET Q q 0 0 0 rg BT 217.36 633.90 Td (the ) Tj ET Q q 0 0 0 rg BT 232.89 633.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 251.75 633.90 Td (of ) Tj ET Q q 0 0 0 rg BT 263.39 633.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 313.90 633.90 Td (products ) Tj ET Q q 0 0 0 rg BT 351.66 633.90 Td (are ) Tj ET Q q 0 0 0 rg BT 367.18 633.90 Td (considered ) Tj ET Q q 0 0 0 rg BT 413.80 633.90 Td (part ) Tj ET Q q 0 0 0 rg BT 432.66 633.90 Td (of ) Tj ET Q q 0 0 0 rg BT 444.31 633.90 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 474.44 633.90 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 510.53 633.90 Td (major ) Tj ET Q q 0 0 0 rg BT 537.17 633.90 Td (or ) Tj ET Q q 0 0 0 rg BT 548.81 633.90 Td (central ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 621.90 Td (operations. ) Tj ET Q q 0 0 0 rg BT 118.29 621.90 Td (Refer ) Tj ET Q q 0 0 0 rg BT 142.64 621.90 Td (to ) Tj ET Q q 0 0 0 rg BT 152.56 621.90 Td ("Revenue ) Tj ET Q q 0 0 0 rg BT 193.76 621.90 Td (Recognition" ) Tj ET Q q 0 0 0 rg BT 248.87 621.90 Td (included ) Tj ET Q q 0 0 0 rg BT 285.44 621.90 Td (in ) Tj ET Q q 0 0 0 rg BT 295.35 621.90 Td ("—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.01 621.90 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.01 621.90 Td (. ) Tj ET Q q 0 0 0 rg BT 340.18 621.90 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 388.97 621.90 Td (Policies" ) Tj ET Q q 0 0 0 rg BT 426.86 621.90 Td (for ) Tj ET Q q 0 0 0 rg BT 440.66 621.90 Td (information ) Tj ET Q q 0 0 0 rg BT 490.01 621.90 Td (regarding ) Tj ET Q q 0 0 0 rg BT 530.46 621.90 Td (recognition ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 609.90 Td (criteria.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 594.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 594.90 Td (Amounts ) Tj ET Q q 0 0 0 rg BT 110.43 594.90 Td (payable ) Tj ET Q q 0 0 0 rg BT 143.29 594.90 Td (to ) Tj ET Q q 0 0 0 rg BT 152.83 594.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 175.72 594.90 Td (by ) Tj ET Q q 0 0 0 rg BT 187.48 594.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 220.33 594.90 Td (partners ) Tj ET Q q 0 0 0 rg BT 254.30 594.90 Td (\(who ) Tj ET Q q 0 0 0 rg BT 276.61 594.90 Td (are ) Tj ET Q q 0 0 0 rg BT 290.58 594.90 Td (the ) Tj ET Q q 0 0 0 rg BT 304.56 594.90 Td (principal ) Tj ET Q q 0 0 0 rg BT 341.87 594.90 Td (in ) Tj ET Q q 0 0 0 rg BT 351.41 594.90 Td (the ) Tj ET Q q 0 0 0 rg BT 365.39 594.90 Td (end ) Tj ET Q q 0 0 0 rg BT 381.59 594.90 Td (customer ) Tj ET Q q 0 0 0 rg BT 420.01 594.90 Td (sale\) ) Tj ET Q q 0 0 0 rg BT 440.65 594.90 Td (for ) Tj ET Q q 0 0 0 rg BT 454.07 594.90 Td (supply ) Tj ET Q q 0 0 0 rg BT 482.50 594.90 Td (of ) Tj ET Q q 0 0 0 rg BT 492.60 594.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 541.56 594.90 Td (products ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 582.90 Td (are ) Tj ET Q q 0 0 0 rg BT 87.52 582.90 Td (included ) Tj ET Q q 0 0 0 rg BT 125.27 582.90 Td (in ) Tj ET Q q 0 0 0 rg BT 136.36 582.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 170.76 582.90 Td (revenue ) Tj ET Q q 0 0 0 rg BT 205.72 582.90 Td (as ) Tj ET Q q 0 0 0 rg BT 217.36 582.90 Td (the ) Tj ET Q q 0 0 0 rg BT 232.89 582.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 251.75 582.90 Td (of ) Tj ET Q q 0 0 0 rg BT 263.39 582.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 313.90 582.90 Td (products ) Tj ET Q q 0 0 0 rg BT 351.66 582.90 Td (are ) Tj ET Q q 0 0 0 rg BT 367.18 582.90 Td (considered ) Tj ET Q q 0 0 0 rg BT 413.80 582.90 Td (part ) Tj ET Q q 0 0 0 rg BT 432.66 582.90 Td (of ) Tj ET Q q 0 0 0 rg BT 444.31 582.90 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 474.44 582.90 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 510.53 582.90 Td (major ) Tj ET Q q 0 0 0 rg BT 537.17 582.90 Td (or ) Tj ET Q q 0 0 0 rg BT 548.81 582.90 Td (central ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 570.90 Td (operations.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 555.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 555.90 Td (Profit ) Tj ET Q q 0 0 0 rg BT 97.11 555.90 Td (sharing, ) Tj ET Q q 0 0 0 rg BT 131.38 555.90 Td (royalties ) Tj ET Q q 0 0 0 rg BT 168.15 555.90 Td (and ) Tj ET Q q 0 0 0 rg BT 184.92 555.90 Td (other ) Tj ET Q q 0 0 0 rg BT 207.80 555.90 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 255.67 555.90 Td (fees ) Tj ET Q q 0 0 0 rg BT 274.10 555.90 Td (payable ) Tj ET Q q 0 0 0 rg BT 307.53 555.90 Td (by ) Tj ET Q q 0 0 0 rg BT 319.86 555.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 343.32 555.90 Td (to ) Tj ET Q q 0 0 0 rg BT 353.43 555.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 386.85 555.90 Td (partners ) Tj ET Q q 0 0 0 rg BT 421.39 555.90 Td (are ) Tj ET Q q 0 0 0 rg BT 435.93 555.90 Td (included ) Tj ET Q q 0 0 0 rg BT 472.70 555.90 Td (in ) Tj ET Q q 0 0 0 rg BT 482.81 555.90 Td (cost ) Tj ET Q q 0 0 0 rg BT 501.25 555.90 Td (of ) Tj ET Q q 0 0 0 rg BT 511.91 555.90 Td (products ) Tj ET Q q 0 0 0 rg BT 548.69 555.90 Td (sold ) Tj ET Q q 0 0 0 rg BT 567.69 555.90 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 543.90 Td (incurred.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 528.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 528.90 Td (Cost ) Tj ET Q q 0 0 0 rg BT 93.12 528.90 Td (reimbursements ) Tj ET Q q 0 0 0 rg BT 159.77 528.90 Td (between ) Tj ET Q q 0 0 0 rg BT 195.86 528.90 Td (the ) Tj ET Q q 0 0 0 rg BT 210.85 528.90 Td (parties ) Tj ET Q q 0 0 0 rg BT 240.29 528.90 Td (are ) Tj ET Q q 0 0 0 rg BT 255.27 528.90 Td (recognized ) Tj ET Q q 0 0 0 rg BT 301.91 528.90 Td (as ) Tj ET Q q 0 0 0 rg BT 313.02 528.90 Td (incurred ) Tj ET Q q 0 0 0 rg BT 349.11 528.90 Td (and ) Tj ET Q q 0 0 0 rg BT 366.33 528.90 Td (included ) Tj ET Q q 0 0 0 rg BT 403.54 528.90 Td (in ) Tj ET Q q 0 0 0 rg BT 414.09 528.90 Td (cost ) Tj ET Q q 0 0 0 rg BT 432.98 528.90 Td (of ) Tj ET Q q 0 0 0 rg BT 444.09 528.90 Td (products ) Tj ET Q q 0 0 0 rg BT 481.30 528.90 Td (sold; ) Tj ET Q q 0 0 0 rg BT 503.53 528.90 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 549.35 528.90 Td (selling ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 516.90 Td (and ) Tj ET Q q 0 0 0 rg BT 89.56 516.90 Td (administrative ) Tj ET Q q 0 0 0 rg BT 149.90 516.90 Td (expenses; ) Tj ET Q q 0 0 0 rg BT 191.90 516.90 Td (or ) Tj ET Q q 0 0 0 rg BT 203.36 516.90 Td (research ) Tj ET Q q 0 0 0 rg BT 239.79 516.90 Td (and ) Tj ET Q q 0 0 0 rg BT 257.36 516.90 Td (development ) Tj ET Q q 0 0 0 rg BT 312.13 516.90 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 353.86 516.90 Td (based ) Tj ET Q q 0 0 0 rg BT 379.75 516.90 Td (on ) Tj ET Q q 0 0 0 rg BT 392.88 516.90 Td (the ) Tj ET Q q 0 0 0 rg BT 408.22 516.90 Td (underlying ) Tj ET Q q 0 0 0 rg BT 454.67 516.90 Td (nature ) Tj ET Q q 0 0 0 rg BT 482.79 516.90 Td (of ) Tj ET Q q 0 0 0 rg BT 494.24 516.90 Td (the ) Tj ET Q q 0 0 0 rg BT 509.59 516.90 Td (related ) Tj ET Q q 0 0 0 rg BT 539.91 516.90 Td (activities ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 504.90 Td (subject ) Tj ET Q q 0 0 0 rg BT 102.83 504.90 Td (to ) Tj ET Q q 0 0 0 rg BT 113.10 504.90 Td (reimbursement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 489.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 489.90 Td (Upfront ) Tj ET Q q 0 0 0 rg BT 105.12 489.90 Td (and ) Tj ET Q q 0 0 0 rg BT 121.02 489.90 Td (contingent ) Tj ET Q q 0 0 0 rg BT 164.69 489.90 Td (development ) Tj ET Q q 0 0 0 rg BT 217.81 489.90 Td (and ) Tj ET Q q 0 0 0 rg BT 233.71 489.90 Td (approval ) Tj ET Q q 0 0 0 rg BT 270.15 489.90 Td (milestones ) Tj ET Q q 0 0 0 rg BT 314.39 489.90 Td (payable ) Tj ET Q q 0 0 0 rg BT 346.94 489.90 Td (to ) Tj ET Q q 0 0 0 rg BT 356.18 489.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 378.77 489.90 Td (by ) Tj ET Q q 0 0 0 rg BT 390.23 489.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 422.78 489.90 Td (partners ) Tj ET Q q 0 0 0 rg BT 456.45 489.90 Td (for ) Tj ET Q q 0 0 0 rg BT 469.57 489.90 Td (investigational ) Tj ET Q q 0 0 0 rg BT 529.91 489.90 Td (compounds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 477.90 Td (and ) Tj ET Q q 0 0 0 rg BT 89.16 477.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 139.07 477.90 Td (products ) Tj ET Q q 0 0 0 rg BT 176.23 477.90 Td (are ) Tj ET Q q 0 0 0 rg BT 191.15 477.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 227.17 477.90 Td (and ) Tj ET Q q 0 0 0 rg BT 244.33 477.90 Td (amortized ) Tj ET Q q 0 0 0 rg BT 287.03 477.90 Td (over ) Tj ET Q q 0 0 0 rg BT 307.51 477.90 Td (the ) Tj ET Q q 0 0 0 rg BT 322.45 477.90 Td (expected ) Tj ET Q q 0 0 0 rg BT 360.70 477.90 Td (period ) Tj ET Q q 0 0 0 rg BT 388.96 477.90 Td (of ) Tj ET Q q 0 0 0 rg BT 400.01 477.90 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 429.54 477.90 Td (co-promotion ) Tj ET Q q 0 0 0 rg BT 486.69 477.90 Td (obligation ) Tj ET Q q 0 0 0 rg BT 529.96 477.90 Td (through ) Tj ET Q q 0 0 0 rg BT 563.79 477.90 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 465.90 Td (market ) Tj ET Q q 0 0 0 rg BT 102.44 465.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 149.00 465.90 Td (period ) Tj ET Q q 0 0 0 rg BT 177.22 465.90 Td (or ) Tj ET Q q 0 0 0 rg BT 188.23 465.90 Td (the ) Tj ET Q q 0 0 0 rg BT 203.12 465.90 Td (periods ) Tj ET Q q 0 0 0 rg BT 235.23 465.90 Td (in ) Tj ET Q q 0 0 0 rg BT 245.69 465.90 Td (which ) Tj ET Q q 0 0 0 rg BT 272.80 465.90 Td (the ) Tj ET Q q 0 0 0 rg BT 287.69 465.90 Td (related ) Tj ET Q q 0 0 0 rg BT 317.57 465.90 Td (compounds ) Tj ET Q q 0 0 0 rg BT 366.36 465.90 Td (or ) Tj ET Q q 0 0 0 rg BT 377.36 465.90 Td (products ) Tj ET Q q 0 0 0 rg BT 414.48 465.90 Td (are ) Tj ET Q q 0 0 0 rg BT 429.36 465.90 Td (expected ) Tj ET Q q 0 0 0 rg BT 467.57 465.90 Td (to ) Tj ET Q q 0 0 0 rg BT 478.02 465.90 Td (contribute ) Tj ET Q q 0 0 0 rg BT 521.24 465.90 Td (to ) Tj ET Q q 0 0 0 rg BT 531.69 465.90 Td (future ) Tj ET Q q 0 0 0 rg BT 558.25 465.90 Td (cash ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 453.90 Td (flows. ) Tj ET Q q 0 0 0 rg BT 99.28 453.90 Td (The ) Tj ET Q q 0 0 0 rg BT 117.58 453.90 Td (amortization ) Tj ET Q q 0 0 0 rg BT 170.88 453.90 Td (is ) Tj ET Q q 0 0 0 rg BT 180.30 453.90 Td (presented ) Tj ET Q q 0 0 0 rg BT 221.37 453.90 Td (consistent ) Tj ET Q q 0 0 0 rg BT 264.13 453.90 Td (with ) Tj ET Q q 0 0 0 rg BT 284.66 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 299.63 453.90 Td (nature ) Tj ET Q q 0 0 0 rg BT 327.37 453.90 Td (of ) Tj ET Q q 0 0 0 rg BT 338.46 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 353.43 453.90 Td (payment ) Tj ET Q q 0 0 0 rg BT 390.62 453.90 Td (under ) Tj ET Q q 0 0 0 rg BT 416.15 453.90 Td (the ) Tj ET Q q 0 0 0 rg BT 431.12 453.90 Td (arrangement. ) Tj ET Q q 0 0 0 rg BT 486.35 453.90 Td (For ) Tj ET Q q 0 0 0 rg BT 503.00 453.90 Td (example, ) Tj ET Q q 0 0 0 rg BT 542.13 453.90 Td (amounts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 441.90 Td (received ) Tj ET Q q 0 0 0 rg BT 108.01 441.90 Td (for ) Tj ET Q q 0 0 0 rg BT 121.82 441.90 Td (investigational ) Tj ET Q q 0 0 0 rg BT 182.85 441.90 Td (compounds ) Tj ET Q q 0 0 0 rg BT 231.11 441.90 Td (are ) Tj ET Q q 0 0 0 rg BT 245.47 441.90 Td (presented ) Tj ET Q q 0 0 0 rg BT 285.94 441.90 Td (in ) Tj ET Q q 0 0 0 rg BT 295.86 441.90 Td (other ) Tj ET Q q 0 0 0 rg BT 318.56 441.90 Td (income ) Tj ET Q q 0 0 0 rg BT 350.15 441.90 Td (\(net\) ) Tj ET Q q 0 0 0 rg BT 371.17 441.90 Td (as ) Tj ET Q q 0 0 0 rg BT 381.66 441.90 Td (the ) Tj ET Q q 0 0 0 rg BT 396.02 441.90 Td (activities ) Tj ET Q q 0 0 0 rg BT 434.27 441.90 Td (being ) Tj ET Q q 0 0 0 rg BT 458.64 441.90 Td (performed ) Tj ET Q q 0 0 0 rg BT 502.44 441.90 Td (at ) Tj ET Q q 0 0 0 rg BT 511.80 441.90 Td (that ) Tj ET Q q 0 0 0 rg BT 528.95 441.90 Td (time ) Tj ET Q q 0 0 0 rg BT 548.88 441.90 Td (are ) Tj ET Q q 0 0 0 rg BT 563.23 441.90 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 429.90 Td (related ) Tj ET Q q 0 0 0 rg BT 102.20 429.90 Td (to ) Tj ET Q q 0 0 0 rg BT 112.97 429.90 Td (the ) Tj ET Q q 0 0 0 rg BT 128.19 429.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 146.73 429.90 Td (of ) Tj ET Q q 0 0 0 rg BT 158.06 429.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 208.25 429.90 Td (products ) Tj ET Q q 0 0 0 rg BT 245.69 429.90 Td (that ) Tj ET Q q 0 0 0 rg BT 263.68 429.90 Td (are ) Tj ET Q q 0 0 0 rg BT 278.89 429.90 Td (part ) Tj ET Q q 0 0 0 rg BT 297.43 429.90 Td (of ) Tj ET Q q 0 0 0 rg BT 308.76 429.90 Td (BMS’) Tj ET Q q 0 0 0 rg BT 332.66 429.90 Td (s ) Tj ET Q q 0 0 0 rg BT 339.55 429.90 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 375.32 429.90 Td (major ) Tj ET Q q 0 0 0 rg BT 401.64 429.90 Td (or ) Tj ET Q q 0 0 0 rg BT 412.97 429.90 Td (central ) Tj ET Q q 0 0 0 rg BT 443.17 429.90 Td (operations; ) Tj ET Q q 0 0 0 rg BT 490.60 429.90 Td (amounts ) Tj ET Q q 0 0 0 rg BT 527.49 429.90 Td (received ) Tj ET Q q 0 0 0 rg BT 564.34 429.90 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 417.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 121.16 417.90 Td (products ) Tj ET Q q 0 0 0 rg BT 157.56 417.90 Td (are ) Tj ET Q q 0 0 0 rg BT 171.73 417.90 Td (presented ) Tj ET Q q 0 0 0 rg BT 212.01 417.90 Td (in ) Tj ET Q q 0 0 0 rg BT 221.75 417.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 254.80 417.90 Td (revenue ) Tj ET Q q 0 0 0 rg BT 288.40 417.90 Td (as ) Tj ET Q q 0 0 0 rg BT 298.70 417.90 Td (the ) Tj ET Q q 0 0 0 rg BT 312.88 417.90 Td (sale ) Tj ET Q q 0 0 0 rg BT 330.38 417.90 Td (of ) Tj ET Q q 0 0 0 rg BT 340.68 417.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 389.83 417.90 Td (products ) Tj ET Q q 0 0 0 rg BT 426.24 417.90 Td (are ) Tj ET Q q 0 0 0 rg BT 440.40 417.90 Td (considered ) Tj ET Q q 0 0 0 rg BT 485.68 417.90 Td (part ) Tj ET Q q 0 0 0 rg BT 503.19 417.90 Td (of ) Tj ET Q q 0 0 0 rg BT 513.48 417.90 Td (BMS’) Tj ET Q q 0 0 0 rg BT 537.38 417.90 Td (s ) Tj ET Q q 0 0 0 rg BT 543.24 417.90 Td (ongoing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 405.90 Td (major ) Tj ET Q q 0 0 0 rg BT 97.34 405.90 Td (or ) Tj ET Q q 0 0 0 rg BT 107.68 405.90 Td (central ) Tj ET Q q 0 0 0 rg BT 136.89 405.90 Td (operations ) Tj ET Q q 0 0 0 rg BT 180.56 405.90 Td (\(except ) Tj ET Q q 0 0 0 rg BT 211.99 405.90 Td (for ) Tj ET Q q 0 0 0 rg BT 225.66 405.90 Td (the ) Tj ET Q q 0 0 0 rg BT 239.44 405.90 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 291.98 405.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 325.08 405.90 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 367.63 405.90 Td (to ) Tj ET Q q 0 0 0 rg BT 377.42 405.90 Td (the ) Tj ET Q q 0 0 0 rg BT 391.20 405.90 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 423.77 405.90 Td (products ) Tj ET Q q 0 0 0 rg BT 460.22 405.90 Td (- ) Tj ET Q q 0 0 0 rg BT 465.56 405.90 Td (see ) Tj ET Q q 0 0 0 rg BT 480.34 405.90 Td (further ) Tj ET Q q 0 0 0 rg BT 509.56 405.90 Td (discussion ) Tj ET Q q 0 0 0 rg BT 553.24 405.90 Td (under ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 393.90 Td (the ) Tj ET Q q 0 0 0 rg BT 86.72 393.90 Td (specific ) Tj ET Q q 0 0 0 rg BT 119.76 393.90 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 172.78 393.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 206.37 393.90 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 249.42 393.90 Td (herein\). ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 377.40 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 377.40 Td (Upfront ) Tj ET Q q 0 0 0 rg BT 106.25 377.40 Td (and ) Tj ET Q q 0 0 0 rg BT 123.27 377.40 Td (contingent ) Tj ET Q q 0 0 0 rg BT 168.07 377.40 Td (approval ) Tj ET Q q 0 0 0 rg BT 205.65 377.40 Td (milestones ) Tj ET Q q 0 0 0 rg BT 251.01 377.40 Td (payable ) Tj ET Q q 0 0 0 rg BT 284.69 377.40 Td (by ) Tj ET Q q 0 0 0 rg BT 297.28 377.40 Td (BMS ) Tj ET Q q 0 0 0 rg BT 320.99 377.40 Td (to ) Tj ET Q q 0 0 0 rg BT 331.36 377.40 Td (alliance ) Tj ET Q q 0 0 0 rg BT 365.03 377.40 Td (partners ) Tj ET Q q 0 0 0 rg BT 399.83 377.40 Td (for ) Tj ET Q q 0 0 0 rg BT 414.08 377.40 Td (commercial ) Tj ET Q q 0 0 0 rg BT 463.86 377.40 Td (products ) Tj ET Q q 0 0 0 rg BT 500.89 377.40 Td (are ) Tj ET Q q 0 0 0 rg BT 515.68 377.40 Td (capitalized ) Tj ET Q q 0 0 0 rg BT 561.58 377.40 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 365.40 Td (amortized ) Tj ET Q q 0 0 0 rg BT 113.85 365.40 Td (over ) Tj ET Q q 0 0 0 rg BT 133.48 365.40 Td (the ) Tj ET Q q 0 0 0 rg BT 147.57 365.40 Td (shorter ) Tj ET Q q 0 0 0 rg BT 177.20 365.40 Td (of ) Tj ET Q q 0 0 0 rg BT 187.40 365.40 Td (the ) Tj ET Q q 0 0 0 rg BT 201.48 365.40 Td (contractual ) Tj ET Q q 0 0 0 rg BT 247.77 365.40 Td (term ) Tj ET Q q 0 0 0 rg BT 267.96 365.40 Td (or ) Tj ET Q q 0 0 0 rg BT 278.16 365.40 Td (the ) Tj ET Q q 0 0 0 rg BT 292.24 365.40 Td (periods ) Tj ET Q q 0 0 0 rg BT 323.54 365.40 Td (in ) Tj ET Q q 0 0 0 rg BT 333.19 365.40 Td (which ) Tj ET Q q 0 0 0 rg BT 359.49 365.40 Td (the ) Tj ET Q q 0 0 0 rg BT 373.58 365.40 Td (related ) Tj ET Q q 0 0 0 rg BT 402.65 365.40 Td (products ) Tj ET Q q 0 0 0 rg BT 438.95 365.40 Td (are ) Tj ET Q q 0 0 0 rg BT 453.03 365.40 Td (expected ) Tj ET Q q 0 0 0 rg BT 490.42 365.40 Td (to ) Tj ET Q q 0 0 0 rg BT 500.07 365.40 Td (contribute ) Tj ET Q q 0 0 0 rg BT 542.48 365.40 Td (to ) Tj ET Q q 0 0 0 rg BT 552.12 365.40 Td (future ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 353.40 Td (cash ) Tj ET Q q 0 0 0 rg BT 92.27 353.40 Td (flows. ) Tj ET Q q 0 0 0 rg BT 119.31 353.40 Td (The ) Tj ET Q q 0 0 0 rg BT 137.36 353.40 Td (amortization ) Tj ET Q q 0 0 0 rg BT 190.39 353.40 Td (is ) Tj ET Q q 0 0 0 rg BT 199.56 353.40 Td (included ) Tj ET Q q 0 0 0 rg BT 236.50 353.40 Td (in ) Tj ET Q q 0 0 0 rg BT 246.78 353.40 Td (cost ) Tj ET Q q 0 0 0 rg BT 265.38 353.40 Td (of ) Tj ET Q q 0 0 0 rg BT 276.21 353.40 Td (products ) Tj ET Q q 0 0 0 rg BT 313.15 353.40 Td (sold.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 336.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 336.90 Td (Upfront ) Tj ET Q q 0 0 0 rg BT 106.32 336.90 Td (and ) Tj ET Q q 0 0 0 rg BT 123.43 336.90 Td (contingent ) Tj ET Q q 0 0 0 rg BT 168.30 336.90 Td (milestones ) Tj ET Q q 0 0 0 rg BT 213.74 336.90 Td (payable ) Tj ET Q q 0 0 0 rg BT 247.50 336.90 Td (by ) Tj ET Q q 0 0 0 rg BT 260.16 336.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 283.95 336.90 Td (to ) Tj ET Q q 0 0 0 rg BT 294.39 336.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 328.14 336.90 Td (partners ) Tj ET Q q 0 0 0 rg BT 363.01 336.90 Td (prior ) Tj ET Q q 0 0 0 rg BT 385.11 336.90 Td (to ) Tj ET Q q 0 0 0 rg BT 395.55 336.90 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 439.31 336.90 Td (approval ) Tj ET Q q 0 0 0 rg BT 476.96 336.90 Td (are ) Tj ET Q q 0 0 0 rg BT 491.83 336.90 Td (expensed ) Tj ET Q q 0 0 0 rg BT 531.70 336.90 Td (as ) Tj ET Q q 0 0 0 rg BT 542.70 336.90 Td (incurred ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 324.90 Td (and ) Tj ET Q q 0 0 0 rg BT 88.94 324.90 Td (included ) Tj ET Q q 0 0 0 rg BT 125.87 324.90 Td (in ) Tj ET Q q 0 0 0 rg BT 136.15 324.90 Td (research ) Tj ET Q q 0 0 0 rg BT 171.96 324.90 Td (and ) Tj ET Q q 0 0 0 rg BT 188.89 324.90 Td (development ) Tj ET Q q 0 0 0 rg BT 243.04 324.90 Td (expenses.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 308.40 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 308.40 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 112.34 308.40 Td (and ) Tj ET Q q 0 0 0 rg BT 129.34 308.40 Td (other ) Tj ET Q q 0 0 0 rg BT 152.45 308.40 Td (contingent ) Tj ET Q q 0 0 0 rg BT 197.22 308.40 Td (consideration ) Tj ET Q q 0 0 0 rg BT 253.66 308.40 Td (payable ) Tj ET Q q 0 0 0 rg BT 287.32 308.40 Td (to ) Tj ET Q q 0 0 0 rg BT 297.66 308.40 Td (BMS ) Tj ET Q q 0 0 0 rg BT 321.35 308.40 Td (by ) Tj ET Q q 0 0 0 rg BT 333.91 308.40 Td (alliance ) Tj ET Q q 0 0 0 rg BT 367.56 308.40 Td (partners ) Tj ET Q q 0 0 0 rg BT 402.33 308.40 Td (related ) Tj ET Q q 0 0 0 rg BT 432.10 308.40 Td (to ) Tj ET Q q 0 0 0 rg BT 442.44 308.40 Td (the ) Tj ET Q q 0 0 0 rg BT 457.22 308.40 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 502.00 308.40 Td (of ) Tj ET Q q 0 0 0 rg BT 512.89 308.40 Td (such ) Tj ET Q q 0 0 0 rg BT 533.78 308.40 Td (businesses ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 296.40 Td (are ) Tj ET Q q 0 0 0 rg BT 86.71 296.40 Td (included ) Tj ET Q q 0 0 0 rg BT 123.64 296.40 Td (in ) Tj ET Q q 0 0 0 rg BT 133.92 296.40 Td (other ) Tj ET Q q 0 0 0 rg BT 156.97 296.40 Td (income ) Tj ET Q q 0 0 0 rg BT 188.90 296.40 Td (when ) Tj ET Q q 0 0 0 rg BT 213.06 296.40 Td (earned.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 279.90 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 279.90 Td (Equity ) Tj ET Q q 0 0 0 rg BT 101.17 279.90 Td (in ) Tj ET Q q 0 0 0 rg BT 111.44 279.90 Td (net ) Tj ET Q q 0 0 0 rg BT 126.16 279.90 Td (income ) Tj ET Q q 0 0 0 rg BT 158.09 279.90 Td (of ) Tj ET Q q 0 0 0 rg BT 168.92 279.90 Td (af) Tj ET Q q 0 0 0 rg BT 176.51 279.90 Td (filiates ) Tj ET Q q 0 0 0 rg BT 206.22 279.90 Td (is ) Tj ET Q q 0 0 0 rg BT 215.39 279.90 Td (included ) Tj ET Q q 0 0 0 rg BT 252.33 279.90 Td (in ) Tj ET Q q 0 0 0 rg BT 262.61 279.90 Td (other ) Tj ET Q q 0 0 0 rg BT 285.65 279.90 Td (income ) Tj ET Q q 0 0 0 rg BT 317.59 279.90 Td (\(net\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 263.40 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 263.40 Td (All ) Tj ET Q q 0 0 0 rg BT 87.22 263.40 Td (payments ) Tj ET Q q 0 0 0 rg BT 127.98 263.40 Td (between ) Tj ET Q q 0 0 0 rg BT 163.73 263.40 Td (BMS ) Tj ET Q q 0 0 0 rg BT 187.29 263.40 Td (and ) Tj ET Q q 0 0 0 rg BT 204.17 263.40 Td (its ) Tj ET Q q 0 0 0 rg BT 216.06 263.40 Td (alliance ) Tj ET Q q 0 0 0 rg BT 249.58 263.40 Td (partners ) Tj ET Q q 0 0 0 rg BT 284.23 263.40 Td (are ) Tj ET Q q 0 0 0 rg BT 298.87 263.40 Td (presented ) Tj ET Q q 0 0 0 rg BT 339.63 263.40 Td (in ) Tj ET Q q 0 0 0 rg BT 349.84 263.40 Td (cash ) Tj ET Q q 0 0 0 rg BT 370.05 263.40 Td (flows ) Tj ET Q q 0 0 0 rg BT 394.71 263.40 Td (from ) Tj ET Q q 0 0 0 rg BT 416.59 263.40 Td (operating ) Tj ET Q q 0 0 0 rg BT 456.79 263.40 Td (activities, ) Tj ET Q q 0 0 0 rg BT 497.82 263.40 Td (except ) Tj ET Q q 0 0 0 rg BT 526.36 263.40 Td (as ) Tj ET Q q 0 0 0 rg BT 537.12 263.40 Td (otherwise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.00 251.40 Td (described ) Tj ET Q q 0 0 0 rg BT 112.82 251.40 Td (below) Tj ET Q q 0 0 0 rg BT 136.60 251.40 Td (.) Tj ET Q endstream endobj 135 0 obj <> endobj 136 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Selected ) Tj ET Q q 0 0 0 rg BT 72.56 749.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 110.23 749.10 Td (information ) Tj ET Q q 0 0 0 rg BT 160.13 749.10 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 203.35 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 213.82 749.10 Td (our ) Tj ET Q q 0 0 0 rg BT 229.84 749.10 Td (alliances ) Tj ET Q q 0 0 0 rg BT 267.50 749.10 Td (was ) Tj ET Q q 0 0 0 rg BT 285.74 749.10 Td (as ) Tj ET Q q 0 0 0 rg BT 296.76 749.10 Td (follows, ) Tj ET Q q 0 0 0 rg BT 331.95 749.10 Td (including ) Tj ET Q q 0 0 0 rg BT 372.41 749.10 Td (net ) Tj ET Q q 0 0 0 rg BT 387.31 749.10 Td (product ) Tj ET Q q 0 0 0 rg BT 420.55 749.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 442.67 749.10 Td (when ) Tj ET Q q 0 0 0 rg BT 467.02 749.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 490.83 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 500.19 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 515.09 749.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 553.32 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 749.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 81.48 737.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 120.84 737.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 139.10 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 153.48 737.10 Td (products ) Tj ET Q q 0 0 0 rg BT 190.63 737.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 221.66 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.15 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 247.08 737.10 Td (alliance. ) Tj ET Q q 0 0 0 rg BT 283.39 737.10 Td (Expenses ) Tj ET Q q 0 0 0 rg BT 323.87 737.10 Td (summarized ) Tj ET Q q 0 0 0 rg BT 375.45 737.10 Td (below ) Tj ET Q q 0 0 0 rg BT 402.60 737.10 Td (do ) Tj ET Q q 0 0 0 rg BT 415.31 737.10 Td (not ) Tj ET Q q 0 0 0 rg BT 430.80 737.10 Td (include ) Tj ET Q q 0 0 0 rg BT 462.95 737.10 Td (all ) Tj ET Q q 0 0 0 rg BT 475.66 737.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 512.26 737.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 553.29 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 563.78 737.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 74.34 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 88.25 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 102.71 725.10 Td (products ) Tj ET Q q 0 0 0 rg BT 139.39 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 149.42 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 163.88 725.10 Td (alliance, ) Tj ET Q q 0 0 0 rg BT 199.71 725.10 Td (but ) Tj ET Q q 0 0 0 rg BT 214.74 725.10 Td (only ) Tj ET Q q 0 0 0 rg BT 234.76 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 249.22 725.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 289.79 725.10 Td (between ) Tj ET Q q 0 0 0 rg BT 325.35 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 339.82 725.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 373.15 725.10 Td (partners ) Tj ET Q q 0 0 0 rg BT 407.60 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 418.18 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 432.64 725.10 Td (related ) Tj ET Q q 0 0 0 rg BT 462.09 725.10 Td (amortization ) Tj ET Q q 0 0 0 rg BT 514.87 725.10 Td (if ) Tj ET Q q 0 0 0 rg BT 523.22 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 537.68 725.10 Td (payments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (were ) Tj ET Q q 0 0 0 rg BT 57.93 713.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 93.73 713.10 Td (or ) Tj ET Q q 0 0 0 rg BT 104.56 713.10 Td (capitalized.) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 679.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 679.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 679.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 679.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 679.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 679.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 653.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 653.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 653.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 653.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 653.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 653.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 627.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 627.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 627.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 627.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 627.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 627.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 601.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 601.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 601.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 601.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 601.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 601.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 575.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 575.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 575.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 575.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 575.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 575.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 549.60 350.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 386.50 549.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 549.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 549.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 549.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 549.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 690.6 m 446.5 690.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 446.5 690.6 m 451.5 690.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 690.6 m 511.5 690.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 690.6 m 516.5 690.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 690.6 m 576.5 690.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 679.6 m 446.5 679.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 679.6 m 511.5 679.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 679.6 m 576.5 679.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 640.6 m 446.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 640.6 m 511.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 640.6 m 576.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 640.6 m 446.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 628.6 m 446.5 628.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 386.5 626.6 m 446.5 626.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 640.6 m 511.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 628.6 m 511.5 628.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 626.6 m 511.5 626.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 640.6 m 576.5 640.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 628.6 m 576.5 628.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 626.6 m 576.5 626.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 436.70 694.68 Td (Y) Tj ET Q q 0 0 0 rg BT 442.03 694.68 Td (ear) Tj ET Q q 0 0 0 rg BT 452.62 694.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 513.35 694.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 682.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 408.00 682.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 473.00 682.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 682.68 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 670.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.73 670.33 Td (om alliances:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 657.17 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.00 657.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 657.17 Td (6,949) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 657.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 657.17 Td (5,568) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 657.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 657.17 Td (4,308) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 644.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 644.17 Td (1,294) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 644.17 Td (1,629) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 644.17 Td (2,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 631.17 Td (T) Tj ET Q q 0 0 0 rg BT 50.41 631.17 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.00 631.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 631.17 Td (8,243) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 631.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 631.17 Td (7,197) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 631.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 631.17 Td (6,716) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 605.33 Td (Payments to/\(fr) Tj ET Q q 0 0 0 rg BT 105.19 605.33 Td (om\) alliance partners:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 592.17 Td (Cost of products sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.00 592.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.15 592.17 Td (2,723) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 592.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.15 592.17 Td (2,129) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 592.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 592.17 Td (1,655) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 579.17 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.30 579.22 Td (\(58) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 442.65 579.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.30 579.22 Td (\(28) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 579.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 579.17 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 566.17 Td (Research and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.65 566.17 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 566.17 Td (56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 566.17 Td (693) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 553.17 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.30 553.22 Td (\(731) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 442.65 553.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 553.22 Td (\(1,009) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 553.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 553.17 Td (\(733) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 553.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 527.17 Td (Noncontrolling interest, pretax) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.65 527.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 527.17 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 527.17 Td (51) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 491.60 412.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 491.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 491.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 491.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 491.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 465.60 412.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 465.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 465.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 465.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 465.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 502.6 m 512.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 491.6 m 512.5 491.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 502.6 m 576.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 491.6 m 576.5 491.6 l s BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 504.38 Td (Selected ) Tj ET Q q 0 0 0 rg BT 75.93 504.38 Td (Alliance Balance Sheet Information:) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 490.75 505.68 Td (December) Tj ET Q q 0 0 0 rg BT 525.32 505.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 494.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 494.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 494.68 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 482.17 Td (Receivables ) Tj ET Q q 0 0 0 rg BT 89.81 482.17 Td (– ) Tj ET Q q 0 0 0 rg BT 97.31 482.17 Td (from ) Tj ET Q q 0 0 0 rg BT 119.25 482.17 Td (alliance ) Tj ET Q q 0 0 0 rg BT 152.84 482.17 Td (partners) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 482.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 482.17 Td (522) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 482.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 482.17 Td (903) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 469.17 Td (Accounts payable – to alliance partners) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 469.17 Td (878) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 469.17 Td (555) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 456.17 Td (Deferred income from alliances) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 165.88 460.70 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 456.17 Td (467) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 456.17 Td (1,194) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 440.50 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 54.00 440.50 Td (Includes ) Tj ET Q q 0 0 0 rg BT 82.29 440.50 Td (unamortized ) Tj ET Q q 0 0 0 rg BT 123.47 440.50 Td (upfront, ) Tj ET Q q 0 0 0 rg BT 150.21 440.50 Td (milestone ) Tj ET Q q 0 0 0 rg BT 182.50 440.50 Td (and ) Tj ET Q q 0 0 0 rg BT 195.25 440.50 Td (other ) Tj ET Q q 0 0 0 rg BT 212.87 440.50 Td (licensing ) Tj ET Q q 0 0 0 rg BT 242.95 440.50 Td (proceeds, ) Tj ET Q q 0 0 0 rg BT 274.57 440.50 Td (revenue ) Tj ET Q q 0 0 0 rg BT 301.07 440.50 Td (deferrals ) Tj ET Q q 0 0 0 rg BT 330.24 440.50 Td (attributed ) Tj ET Q q 0 0 0 rg BT 362.09 440.50 Td (to ) Tj ET Q BT /F3 8.00 Tf ET q 0 0 0 rg BT 369.50 440.50 Td (Atripla*) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 396.17 440.50 Td ( ) Tj ET Q q 0 0 0 rg BT 397.36 440.50 Td (and ) Tj ET Q q 0 0 0 rg BT 410.10 440.50 Td (undelivered ) Tj ET Q q 0 0 0 rg BT 449.06 440.50 Td (elements ) Tj ET Q q 0 0 0 rg BT 478.68 440.50 Td (of ) Tj ET Q q 0 0 0 rg BT 486.53 440.50 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 513.94 440.50 Td (business ) Tj ET Q q 0 0 0 rg BT 542.24 440.50 Td (divestiture ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 430.90 Td (proceeds. ) Tj ET Q q 0 0 0 rg BT 85.99 430.90 Td (Amortization ) Tj ET Q q 0 0 0 rg BT 130.64 430.90 Td (of ) Tj ET Q q 0 0 0 rg BT 139.31 430.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 167.95 430.90 Td (income ) Tj ET Q q 0 0 0 rg BT 193.50 430.90 Td (\(primarily ) Tj ET Q q 0 0 0 rg BT 227.93 430.90 Td (related ) Tj ET Q q 0 0 0 rg BT 251.70 430.90 Td (to ) Tj ET Q q 0 0 0 rg BT 259.92 430.90 Td (alliances\) ) Tj ET Q q 0 0 0 rg BT 292.57 430.90 Td (was ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 307.01 430.90 Td ($83 ) Tj ET Q q 0 0 0 rg BT 321.01 430.90 Td (million) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 344.12 430.90 Td ( ) Tj ET Q q 0 0 0 rg BT 346.12 430.90 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 354.34 430.90 Td (2017) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 370.34 430.90 Td (, ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 374.34 430.90 Td ($244 ) Tj ET Q q 0 0 0 rg BT 392.34 430.90 Td (million) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 415.46 430.90 Td ( ) Tj ET Q q 0 0 0 rg BT 417.46 430.90 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 425.68 430.90 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 441.68 430.90 Td ( ) Tj ET Q q 0 0 0 rg BT 443.68 430.90 Td (and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 457.23 430.90 Td ($307 ) Tj ET Q q 0 0 0 rg BT 475.23 430.90 Td (million) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 498.34 430.90 Td ( ) Tj ET Q q 0 0 0 rg BT 500.34 430.90 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 508.57 430.90 Td (2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 524.57 430.90 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 406.90 Td (Upfront ) Tj ET Q q 0 0 0 rg BT 69.35 406.90 Td (payments ) Tj ET Q q 0 0 0 rg BT 109.36 406.90 Td (for ) Tj ET Q q 0 0 0 rg BT 122.71 406.90 Td (new ) Tj ET Q q 0 0 0 rg BT 141.05 406.90 Td (licensing ) Tj ET Q q 0 0 0 rg BT 178.84 406.90 Td (and ) Tj ET Q q 0 0 0 rg BT 194.97 406.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 227.75 406.90 Td (agreements ) Tj ET Q q 0 0 0 rg BT 274.96 406.90 Td (\(including ) Tj ET Q q 0 0 0 rg BT 317.76 406.90 Td (options ) Tj ET Q q 0 0 0 rg BT 348.89 406.90 Td (to ) Tj ET Q q 0 0 0 rg BT 358.36 406.90 Td (license ) Tj ET Q q 0 0 0 rg BT 387.81 406.90 Td (or ) Tj ET Q q 0 0 0 rg BT 397.82 406.90 Td (acquire ) Tj ET Q q 0 0 0 rg BT 428.93 406.90 Td (the ) Tj ET Q q 0 0 0 rg BT 442.84 406.90 Td (related ) Tj ET Q q 0 0 0 rg BT 471.73 406.90 Td (assets\) ) Tj ET Q q 0 0 0 rg BT 500.07 406.90 Td (char) Tj ET Q q 0 0 0 rg BT 517.10 406.90 Td (ged ) Tj ET Q q 0 0 0 rg BT 533.23 406.90 Td (to ) Tj ET Q q 0 0 0 rg BT 542.69 406.90 Td (research ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 394.90 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 394.90 Td (development ) Tj ET Q q 0 0 0 rg BT 107.09 394.90 Td (expenses ) Tj ET Q q 0 0 0 rg BT 145.69 394.90 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 167.62 394.90 Td ($41 ) Tj ET Q q 0 0 0 rg BT 185.12 394.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.01 394.90 Td ( ) Tj ET Q q 0 0 0 rg BT 216.51 394.90 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 226.79 394.90 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 246.79 394.90 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.79 394.90 Td ($15 ) Tj ET Q q 0 0 0 rg BT 269.29 394.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.18 394.90 Td ( ) Tj ET Q q 0 0 0 rg BT 300.68 394.90 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.96 394.90 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 330.96 394.90 Td ( ) Tj ET Q q 0 0 0 rg BT 333.46 394.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.39 394.90 Td ($619 ) Tj ET Q q 0 0 0 rg BT 372.89 394.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.79 394.90 Td ( ) Tj ET Q q 0 0 0 rg BT 404.29 394.90 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.56 394.90 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.56 394.90 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 370.90 Td (Specific ) Tj ET Q q 0 0 0 rg BT 70.92 370.90 Td (information ) Tj ET Q q 0 0 0 rg BT 120.29 370.90 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 163.00 370.90 Td (to ) Tj ET Q q 0 0 0 rg BT 172.93 370.90 Td (each ) Tj ET Q q 0 0 0 rg BT 193.41 370.90 Td (of ) Tj ET Q q 0 0 0 rg BT 203.90 370.90 Td (our ) Tj ET Q q 0 0 0 rg BT 219.39 370.90 Td (significant ) Tj ET Q q 0 0 0 rg BT 263.76 370.90 Td (alliances ) Tj ET Q q 0 0 0 rg BT 300.90 370.90 Td (is ) Tj ET Q q 0 0 0 rg BT 309.73 370.90 Td (discussed ) Tj ET Q q 0 0 0 rg BT 350.22 370.90 Td (below) Tj ET Q q 0 0 0 rg BT 374.01 370.90 Td (, ) Tj ET Q q 0 0 0 rg BT 378.67 370.90 Td (including ) Tj ET Q q 0 0 0 rg BT 418.60 370.90 Td (their ) Tj ET Q q 0 0 0 rg BT 439.09 370.90 Td (nature ) Tj ET Q q 0 0 0 rg BT 466.23 370.90 Td (and ) Tj ET Q q 0 0 0 rg BT 482.83 370.90 Td (purpose; ) Tj ET Q q 0 0 0 rg BT 519.43 370.90 Td (the ) Tj ET Q q 0 0 0 rg BT 533.80 370.90 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 358.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 62.68 358.90 Td (and ) Tj ET Q q 0 0 0 rg BT 81.01 358.90 Td (obligations ) Tj ET Q q 0 0 0 rg BT 129.35 358.90 Td (of ) Tj ET Q q 0 0 0 rg BT 141.58 358.90 Td (the ) Tj ET Q q 0 0 0 rg BT 157.69 358.90 Td (parties; ) Tj ET Q q 0 0 0 rg BT 191.03 358.90 Td (specific ) Tj ET Q q 0 0 0 rg BT 226.02 358.90 Td (accounting ) Tj ET Q q 0 0 0 rg BT 273.79 358.90 Td (policy ) Tj ET Q q 0 0 0 rg BT 302.68 358.90 Td (elections; ) Tj ET Q q 0 0 0 rg BT 344.90 358.90 Td (and ) Tj ET Q q 0 0 0 rg BT 363.23 358.90 Td (the ) Tj ET Q q 0 0 0 rg BT 379.35 358.90 Td (income ) Tj ET Q q 0 0 0 rg BT 412.68 358.90 Td (statement ) Tj ET Q q 0 0 0 rg BT 454.90 358.90 Td (classification ) Tj ET Q q 0 0 0 rg BT 511.55 358.90 Td (of ) Tj ET Q q 0 0 0 rg BT 523.78 358.90 Td (and ) Tj ET Q q 0 0 0 rg BT 542.12 358.90 Td (amounts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 346.90 Td (attributable ) Tj ET Q q 0 0 0 rg BT 84.04 346.90 Td (to ) Tj ET Q q 0 0 0 rg BT 94.32 346.90 Td (payments ) Tj ET Q q 0 0 0 rg BT 135.14 346.90 Td (between ) Tj ET Q q 0 0 0 rg BT 170.96 346.90 Td (the ) Tj ET Q q 0 0 0 rg BT 185.67 346.90 Td (parties.) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 321.33505859375 m 61.44189453125 321.33505859375 l s q 0 0 0 rg BT 36.00 322.90 Td (Pfizer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 298.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.79 298.90 Td (and ) Tj ET Q q 0 0 0 rg BT 76.89 298.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 103.43 298.90 Td (jointly ) Tj ET Q q 0 0 0 rg BT 132.20 298.90 Td (develop ) Tj ET Q q 0 0 0 rg BT 166.52 298.90 Td (and ) Tj ET Q q 0 0 0 rg BT 183.62 298.90 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 245.14 298.90 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 273.47 298.90 Td (, ) Tj ET Q q 0 0 0 rg BT 278.63 298.90 Td (an ) Tj ET Q q 0 0 0 rg BT 290.73 298.90 Td (anticoagulant ) Tj ET Q q 0 0 0 rg BT 347.26 298.90 Td (discovered ) Tj ET Q q 0 0 0 rg BT 393.24 298.90 Td (by ) Tj ET Q q 0 0 0 rg BT 405.91 298.90 Td (BMS. ) Tj ET Q q 0 0 0 rg BT 432.19 298.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 458.73 298.90 Td (funds ) Tj ET Q q 0 0 0 rg BT 483.61 298.90 Td (between ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.59 298.90 Td (50%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 537.92 298.90 Td ( ) Tj ET Q q 0 0 0 rg BT 540.59 298.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.69 298.90 Td (60%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 286.90 Td (of ) Tj ET Q q 0 0 0 rg BT 46.53 286.90 Td (all ) Tj ET Q q 0 0 0 rg BT 58.72 286.90 Td (development ) Tj ET Q q 0 0 0 rg BT 112.56 286.90 Td (costs ) Tj ET Q q 0 0 0 rg BT 134.76 286.90 Td (depending ) Tj ET Q q 0 0 0 rg BT 178.61 286.90 Td (on ) Tj ET Q q 0 0 0 rg BT 190.81 286.90 Td (the ) Tj ET Q q 0 0 0 rg BT 205.22 286.90 Td (study) Tj ET Q q 0 0 0 rg BT 226.24 286.90 Td (. ) Tj ET Q q 0 0 0 rg BT 230.94 286.90 Td (Profits ) Tj ET Q q 0 0 0 rg BT 259.80 286.90 Td (and ) Tj ET Q q 0 0 0 rg BT 276.44 286.90 Td (losses ) Tj ET Q q 0 0 0 rg BT 302.53 286.90 Td (are ) Tj ET Q q 0 0 0 rg BT 316.93 286.90 Td (shared ) Tj ET Q q 0 0 0 rg BT 345.23 286.90 Td (equally ) Tj ET Q q 0 0 0 rg BT 376.86 286.90 Td (on ) Tj ET Q q 0 0 0 rg BT 389.05 286.90 Td (a ) Tj ET Q q 0 0 0 rg BT 395.69 286.90 Td (global ) Tj ET Q q 0 0 0 rg BT 422.88 286.90 Td (basis ) Tj ET Q q 0 0 0 rg BT 445.07 286.90 Td (except ) Tj ET Q q 0 0 0 rg BT 473.36 286.90 Td (in ) Tj ET Q q 0 0 0 rg BT 483.34 286.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 512.74 286.90 Td (countries ) Tj ET Q q 0 0 0 rg BT 551.59 286.90 Td (where ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 274.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 62.38 274.90 Td (commercializes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 127.62 274.90 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 155.96 274.90 Td ( ) Tj ET Q q 0 0 0 rg BT 158.46 274.90 Td (and ) Tj ET Q q 0 0 0 rg BT 175.39 274.90 Td (pays ) Tj ET Q q 0 0 0 rg BT 196.22 274.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 219.85 274.90 Td (a ) Tj ET Q q 0 0 0 rg BT 226.79 274.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 248.72 274.90 Td (based ) Tj ET Q q 0 0 0 rg BT 273.99 274.90 Td (fee. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 250.90 Td (Co-exclusive ) Tj ET Q q 0 0 0 rg BT 91.53 250.90 Td (license ) Tj ET Q q 0 0 0 rg BT 122.07 250.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 147.62 250.90 Td (were ) Tj ET Q q 0 0 0 rg BT 169.82 250.90 Td (granted ) Tj ET Q q 0 0 0 rg BT 202.57 250.90 Td (to ) Tj ET Q q 0 0 0 rg BT 213.12 250.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 239.77 250.90 Td (in ) Tj ET Q q 0 0 0 rg BT 250.32 250.90 Td (exchange ) Tj ET Q q 0 0 0 rg BT 290.85 250.90 Td (for ) Tj ET Q q 0 0 0 rg BT 305.28 250.90 Td (an ) Tj ET Q q 0 0 0 rg BT 317.49 250.90 Td (upfront ) Tj ET Q q 0 0 0 rg BT 349.70 250.90 Td (payment ) Tj ET Q q 0 0 0 rg BT 386.90 250.90 Td (and ) Tj ET Q q 0 0 0 rg BT 404.11 250.90 Td (potential ) Tj ET Q q 0 0 0 rg BT 441.87 250.90 Td (milestone ) Tj ET Q q 0 0 0 rg BT 483.52 250.90 Td (payments. ) Tj ET Q q 0 0 0 rg BT 527.12 250.90 Td (Both ) Tj ET Q q 0 0 0 rg BT 549.34 250.90 Td (parties ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 238.90 Td (assumed ) Tj ET Q q 0 0 0 rg BT 72.73 238.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 102.23 238.90 Td (obligations ) Tj ET Q q 0 0 0 rg BT 148.97 238.90 Td (to ) Tj ET Q q 0 0 0 rg BT 159.04 238.90 Td (actively ) Tj ET Q q 0 0 0 rg BT 192.98 238.90 Td (participate ) Tj ET Q q 0 0 0 rg BT 237.47 238.90 Td (in ) Tj ET Q q 0 0 0 rg BT 247.55 238.90 Td (a ) Tj ET Q q 0 0 0 rg BT 254.28 238.90 Td (joint ) Tj ET Q q 0 0 0 rg BT 274.91 238.90 Td (executive ) Tj ET Q q 0 0 0 rg BT 315.51 238.90 Td (committee ) Tj ET Q q 0 0 0 rg BT 360.01 238.90 Td (and ) Tj ET Q q 0 0 0 rg BT 376.75 238.90 Td (various ) Tj ET Q q 0 0 0 rg BT 408.48 238.90 Td (other ) Tj ET Q q 0 0 0 rg BT 431.32 238.90 Td (operating ) Tj ET Q q 0 0 0 rg BT 471.38 238.90 Td (committees ) Tj ET Q q 0 0 0 rg BT 519.77 238.90 Td (and ) Tj ET Q q 0 0 0 rg BT 536.50 238.90 Td (have ) Tj ET Q q 0 0 0 rg BT 557.67 238.90 Td (joint ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 226.90 Td (responsibilities ) Tj ET Q q 0 0 0 rg BT 99.62 226.90 Td (for ) Tj ET Q q 0 0 0 rg BT 114.34 226.90 Td (the ) Tj ET Q q 0 0 0 rg BT 129.63 226.90 Td (research, ) Tj ET Q q 0 0 0 rg BT 168.50 226.90 Td (development, ) Tj ET Q q 0 0 0 rg BT 225.71 226.90 Td (distribution, ) Tj ET Q q 0 0 0 rg BT 277.39 226.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 299.89 226.90 Td (and ) Tj ET Q q 0 0 0 rg BT 317.40 226.90 Td (marketing ) Tj ET Q q 0 0 0 rg BT 361.01 226.90 Td (activities ) Tj ET Q q 0 0 0 rg BT 400.17 226.90 Td (of ) Tj ET Q q 0 0 0 rg BT 411.57 226.90 Td (the ) Tj ET Q q 0 0 0 rg BT 426.85 226.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 461.00 226.90 Td (using ) Tj ET Q q 0 0 0 rg BT 485.74 226.90 Td (resources ) Tj ET Q q 0 0 0 rg BT 526.56 226.90 Td (in ) Tj ET Q q 0 0 0 rg BT 537.41 226.90 Td (their ) Tj ET Q q 0 0 0 rg BT 558.80 226.90 Td (own ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 214.90 Td (infrastructures. ) Tj ET Q q 0 0 0 rg BT 98.09 214.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 121.04 214.90 Td (manufactures ) Tj ET Q q 0 0 0 rg BT 176.74 214.90 Td (the ) Tj ET Q q 0 0 0 rg BT 190.79 214.90 Td (product ) Tj ET Q q 0 0 0 rg BT 223.17 214.90 Td (in ) Tj ET Q q 0 0 0 rg BT 232.78 214.90 Td (the ) Tj ET Q q 0 0 0 rg BT 246.83 214.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 279.75 214.90 Td (and ) Tj ET Q q 0 0 0 rg BT 296.02 214.90 Td (is ) Tj ET Q q 0 0 0 rg BT 304.52 214.90 Td (the ) Tj ET Q q 0 0 0 rg BT 318.57 214.90 Td (principal ) Tj ET Q q 0 0 0 rg BT 355.94 214.90 Td (in ) Tj ET Q q 0 0 0 rg BT 365.56 214.90 Td (the ) Tj ET Q q 0 0 0 rg BT 379.60 214.90 Td (end ) Tj ET Q q 0 0 0 rg BT 395.88 214.90 Td (customer ) Tj ET Q q 0 0 0 rg BT 434.36 214.90 Td (product ) Tj ET Q q 0 0 0 rg BT 466.74 214.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 488.01 214.90 Td (in ) Tj ET Q q 0 0 0 rg BT 497.62 214.90 Td (the ) Tj ET Q q 0 0 0 rg BT 511.67 214.90 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 533.79 214.90 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 202.90 Td (countries ) Tj ET Q q 0 0 0 rg BT 74.71 202.90 Td (in ) Tj ET Q q 0 0 0 rg BT 84.53 202.90 Td (Europe, ) Tj ET Q q 0 0 0 rg BT 117.96 202.90 Td (as ) Tj ET Q q 0 0 0 rg BT 128.34 202.90 Td (well ) Tj ET Q q 0 0 0 rg BT 147.61 202.90 Td (as ) Tj ET Q q 0 0 0 rg BT 157.99 202.90 Td (Canada, ) Tj ET Q q 0 0 0 rg BT 192.07 202.90 Td (Australia, ) Tj ET Q q 0 0 0 rg BT 233.27 202.90 Td (China, ) Tj ET Q q 0 0 0 rg BT 261.71 202.90 Td (Japan ) Tj ET Q q 0 0 0 rg BT 286.53 202.90 Td (and ) Tj ET Q q 0 0 0 rg BT 303.02 202.90 Td (South ) Tj ET Q q 0 0 0 rg BT 328.41 202.90 Td (Korea. ) Tj ET Q q 0 0 0 rg BT 357.39 202.90 Td (In ) Tj ET Q q 0 0 0 rg BT 367.77 202.90 Td (2015, ) Tj ET Q q 0 0 0 rg BT 392.31 202.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 415.49 202.90 Td (transferred ) Tj ET Q q 0 0 0 rg BT 460.84 202.90 Td (full ) Tj ET Q q 0 0 0 rg BT 476.78 202.90 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 553.24 202.90 Td (rights ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 190.90 Td (to ) Tj ET Q q 0 0 0 rg BT 46.38 190.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 72.86 190.90 Td (in ) Tj ET Q q 0 0 0 rg BT 83.23 190.90 Td (certain ) Tj ET Q q 0 0 0 rg BT 113.04 190.90 Td (smaller ) Tj ET Q q 0 0 0 rg BT 145.07 190.90 Td (countries ) Tj ET Q q 0 0 0 rg BT 184.33 190.90 Td (in ) Tj ET Q q 0 0 0 rg BT 194.70 190.90 Td (order ) Tj ET Q q 0 0 0 rg BT 218.40 190.90 Td (to ) Tj ET Q q 0 0 0 rg BT 228.78 190.90 Td (simplify ) Tj ET Q q 0 0 0 rg BT 264.72 190.90 Td (operations. ) Tj ET Q q 0 0 0 rg BT 311.47 190.90 Td (In ) Tj ET Q q 0 0 0 rg BT 322.40 190.90 Td (the ) Tj ET Q q 0 0 0 rg BT 337.22 190.90 Td (transferred ) Tj ET Q q 0 0 0 rg BT 383.12 190.90 Td (countries, ) Tj ET Q q 0 0 0 rg BT 424.88 190.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 448.60 190.90 Td (supplies ) Tj ET Q q 0 0 0 rg BT 483.98 190.90 Td (the ) Tj ET Q q 0 0 0 rg BT 498.80 190.90 Td (product ) Tj ET Q q 0 0 0 rg BT 531.94 190.90 Td (to ) Tj ET Q q 0 0 0 rg BT 542.32 190.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 568.80 190.90 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 178.90 Td (cost ) Tj ET Q q 0 0 0 rg BT 54.61 178.90 Td (plus ) Tj ET Q q 0 0 0 rg BT 73.78 178.90 Td (a ) Tj ET Q q 0 0 0 rg BT 80.72 178.90 Td (percentage ) Tj ET Q q 0 0 0 rg BT 126.52 178.90 Td (of ) Tj ET Q q 0 0 0 rg BT 137.35 178.90 Td (the ) Tj ET Q q 0 0 0 rg BT 152.06 178.90 Td (net ) Tj ET Q q 0 0 0 rg BT 166.78 178.90 Td (sales ) Tj ET Q q 0 0 0 rg BT 188.72 178.90 Td (price ) Tj ET Q q 0 0 0 rg BT 211.21 178.90 Td (to ) Tj ET Q q 0 0 0 rg BT 221.48 178.90 Td (end-customers.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 154.90 Td (The ) Tj ET Q q 0 0 0 rg BT 54.01 154.90 Td (Company ) Tj ET Q q 0 0 0 rg BT 95.37 154.90 Td (determined ) Tj ET Q q 0 0 0 rg BT 142.82 154.90 Td (the ) Tj ET Q q 0 0 0 rg BT 157.50 154.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 182.75 154.90 Td (transferred ) Tj ET Q q 0 0 0 rg BT 228.52 154.90 Td (to ) Tj ET Q q 0 0 0 rg BT 238.76 154.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 265.11 154.90 Td (did ) Tj ET Q q 0 0 0 rg BT 280.35 154.90 Td (not ) Tj ET Q q 0 0 0 rg BT 295.60 154.90 Td (have ) Tj ET Q q 0 0 0 rg BT 316.94 154.90 Td (standalone ) Tj ET Q q 0 0 0 rg BT 362.17 154.90 Td (value ) Tj ET Q q 0 0 0 rg BT 386.30 154.90 Td (as ) Tj ET Q q 0 0 0 rg BT 397.09 154.90 Td (such ) Tj ET Q q 0 0 0 rg BT 417.89 154.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 443.14 154.90 Td (were ) Tj ET Q q 0 0 0 rg BT 465.03 154.90 Td (not ) Tj ET Q q 0 0 0 rg BT 480.28 154.90 Td (sold ) Tj ET Q q 0 0 0 rg BT 499.42 154.90 Td (separately ) Tj ET Q q 0 0 0 rg BT 542.42 154.90 Td (by ) Tj ET Q q 0 0 0 rg BT 554.88 154.90 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 142.90 Td (or ) Tj ET Q q 0 0 0 rg BT 47.11 142.90 Td (any ) Tj ET Q q 0 0 0 rg BT 64.32 142.90 Td (other ) Tj ET Q q 0 0 0 rg BT 87.65 142.90 Td (party) Tj ET Q q 0 0 0 rg BT 107.54 142.90 Td (, ) Tj ET Q q 0 0 0 rg BT 112.82 142.90 Td (nor ) Tj ET Q q 0 0 0 rg BT 128.93 142.90 Td (could ) Tj ET Q q 0 0 0 rg BT 153.92 142.90 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 180.58 142.90 Td (receive ) Tj ET Q q 0 0 0 rg BT 212.22 142.90 Td (any ) Tj ET Q q 0 0 0 rg BT 229.43 142.90 Td (benefit ) Tj ET Q q 0 0 0 rg BT 259.97 142.90 Td (for ) Tj ET Q q 0 0 0 rg BT 274.41 142.90 Td (the ) Tj ET Q q 0 0 0 rg BT 289.41 142.90 Td (delivered ) Tj ET Q q 0 0 0 rg BT 329.39 142.90 Td (rights ) Tj ET Q q 0 0 0 rg BT 354.94 142.90 Td (without ) Tj ET Q q 0 0 0 rg BT 388.28 142.90 Td (the ) Tj ET Q q 0 0 0 rg BT 403.27 142.90 Td (fulfillment ) Tj ET Q q 0 0 0 rg BT 448.82 142.90 Td (of ) Tj ET Q q 0 0 0 rg BT 459.92 142.90 Td (other ) Tj ET Q q 0 0 0 rg BT 483.25 142.90 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 518.80 142.90 Td (obligations ) Tj ET Q q 0 0 0 rg BT 566.02 142.90 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 130.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.48 130.90 Td (under ) Tj ET Q q 0 0 0 rg BT 84.60 130.90 Td (the ) Tj ET Q q 0 0 0 rg BT 99.17 130.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 132.62 130.90 Td (agreement, ) Tj ET Q q 0 0 0 rg BT 179.11 130.90 Td (including ) Tj ET Q q 0 0 0 rg BT 219.24 130.90 Td (the ) Tj ET Q q 0 0 0 rg BT 233.81 130.90 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 273.93 130.90 Td (supply ) Tj ET Q q 0 0 0 rg BT 302.96 130.90 Td (arrangement. ) Tj ET Q q 0 0 0 rg BT 357.26 130.90 Td (As ) Tj ET Q q 0 0 0 rg BT 370.73 130.90 Td (such, ) Tj ET Q q 0 0 0 rg BT 393.92 130.90 Td (the ) Tj ET Q q 0 0 0 rg BT 408.49 130.90 Td (global ) Tj ET Q q 0 0 0 rg BT 435.84 130.90 Td (alliance ) Tj ET Q q 0 0 0 rg BT 469.28 130.90 Td (was ) Tj ET Q q 0 0 0 rg BT 487.19 130.90 Td (treated ) Tj ET Q q 0 0 0 rg BT 516.75 130.90 Td (as ) Tj ET Q q 0 0 0 rg BT 527.43 130.90 Td (a ) Tj ET Q q 0 0 0 rg BT 534.22 130.90 Td (single ) Tj ET Q q 0 0 0 rg BT 560.47 130.90 Td (unit ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 118.90 Td (of ) Tj ET Q q 0 0 0 rg BT 46.55 118.90 Td (accounting ) Tj ET Q q 0 0 0 rg BT 92.65 118.90 Td (and ) Tj ET Q q 0 0 0 rg BT 109.31 118.90 Td (upfront ) Tj ET Q q 0 0 0 rg BT 140.98 118.90 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 178.74 118.90 Td (and ) Tj ET Q q 0 0 0 rg BT 195.40 118.90 Td (any ) Tj ET Q q 0 0 0 rg BT 212.06 118.90 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 258.72 118.90 Td (contingent ) Tj ET Q q 0 0 0 rg BT 303.16 118.90 Td (milestone ) Tj ET Q q 0 0 0 rg BT 344.27 118.90 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 382.03 118.90 Td (are ) Tj ET Q q 0 0 0 rg BT 396.46 118.90 Td (amortized ) Tj ET Q q 0 0 0 rg BT 438.66 118.90 Td (over ) Tj ET Q q 0 0 0 rg BT 458.66 118.90 Td (the ) Tj ET Q q 0 0 0 rg BT 473.10 118.90 Td (expected ) Tj ET Q q 0 0 0 rg BT 510.85 118.90 Td (period ) Tj ET Q q 0 0 0 rg BT 538.62 118.90 Td (of ) Tj ET Q q 0 0 0 rg BT 549.18 118.90 Td (BMS's ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 106.90 Td (co-promotion ) Tj ET Q q 0 0 0 rg BT 93.37 106.90 Td (obligation ) Tj ET Q q 0 0 0 rg BT 136.85 106.90 Td (through ) Tj ET Q q 0 0 0 rg BT 170.89 106.90 Td (the ) Tj ET Q q 0 0 0 rg BT 186.04 106.90 Td (market ) Tj ET Q q 0 0 0 rg BT 216.74 106.90 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 263.56 106.90 Td (period. ) Tj ET Q q 0 0 0 rg BT 294.54 106.90 Td (BMS ) Tj ET Q q 0 0 0 rg BT 318.59 106.90 Td (received ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 355.39 106.90 Td ($884 ) Tj ET Q q 0 0 0 rg BT 378.32 106.90 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.22 106.90 Td ( ) Tj ET Q q 0 0 0 rg BT 410.15 106.90 Td (in ) Tj ET Q q 0 0 0 rg BT 420.86 106.90 Td (non-refundable ) Tj ET Q q 0 0 0 rg BT 484.88 106.90 Td (upfront, ) Tj ET Q q 0 0 0 rg BT 519.75 106.90 Td (milestone ) Tj ET Q q 0 0 0 rg BT 561.57 106.90 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 94.90 Td (other ) Tj ET Q q 0 0 0 rg BT 58.69 94.90 Td (licensing ) Tj ET Q q 0 0 0 rg BT 96.93 94.90 Td (payments ) Tj ET Q q 0 0 0 rg BT 137.39 94.90 Td (related ) Tj ET Q q 0 0 0 rg BT 166.73 94.90 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 176.65 94.90 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 204.98 94.90 Td ( ) Tj ET Q q 0 0 0 rg BT 207.12 94.90 Td (through ) Tj ET Q q 0 0 0 rg BT 240.37 94.90 Td (December ) Tj ET Q q 0 0 0 rg BT 283.59 94.90 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.23 94.90 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.23 94.90 Td (. ) Tj ET Q q 0 0 0 rg BT 322.40 94.90 Td (Amortization ) Tj ET Q q 0 0 0 rg BT 377.86 94.90 Td (of ) Tj ET Q q 0 0 0 rg BT 388.33 94.90 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 402.68 94.90 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.02 94.90 Td ( ) Tj ET Q q 0 0 0 rg BT 433.15 94.90 Td (deferred ) Tj ET Q q 0 0 0 rg BT 468.60 94.90 Td (income ) Tj ET Q q 0 0 0 rg BT 500.17 94.90 Td (is ) Tj ET Q q 0 0 0 rg BT 508.98 94.90 Td (included ) Tj ET Q q 0 0 0 rg BT 545.55 94.90 Td (in ) Tj ET Q q 0 0 0 rg BT 555.47 94.90 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 82.90 Td (income ) Tj ET Q q 0 0 0 rg BT 67.93 82.90 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 78.76 82.90 Td (Eliquis ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 109.60 82.90 Td (was ) Tj ET Q q 0 0 0 rg BT 127.65 82.90 Td (not ) Tj ET Q q 0 0 0 rg BT 142.93 82.90 Td (a ) Tj ET Q q 0 0 0 rg BT 149.87 82.90 Td (commercial ) Tj ET Q q 0 0 0 rg BT 199.56 82.90 Td (product ) Tj ET Q q 0 0 0 rg BT 232.61 82.90 Td (at ) Tj ET Q q 0 0 0 rg BT 242.33 82.90 Td (the ) Tj ET Q q 0 0 0 rg BT 257.04 82.90 Td (commencement ) Tj ET Q q 0 0 0 rg BT 322.85 82.90 Td (of ) Tj ET Q q 0 0 0 rg BT 333.68 82.90 Td (the ) Tj ET Q q 0 0 0 rg BT 348.40 82.90 Td (alliance.) Tj ET Q endstream endobj 137 0 obj <> endobj 138 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (68) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Summarized financial information related to this alliance was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 712.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 686.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 660.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 634.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 634.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 634.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 634.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 725.6 m 448.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 725.6 m 452.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 725.6 m 512.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 725.6 m 516.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 725.6 m 576.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 712.6 m 448.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 712.6 m 512.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 712.6 m 576.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 673.6 m 448.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 661.6 m 448.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 659.6 m 448.5 659.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 673.6 m 512.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 661.6 m 512.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 659.6 m 512.5 659.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 673.6 m 576.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 661.6 m 576.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 659.6 m 576.5 659.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 729.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 729.83 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 729.83 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 729.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 729.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 716.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 716.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 716.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 716.83 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 703.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.73 703.33 Td (om Pfizer) Tj ET Q q 0 0 0 rg BT 130.91 703.33 Td ( alliance:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 690.17 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.15 690.17 Td (4,808) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 690.17 Td (3,306) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 690.17 Td (1,849) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 677.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 677.17 Td (64) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 677.17 Td (37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 677.17 Td (1) Tj ET Q q 0 0 0 rg BT 567.65 677.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 664.17 Td (T) Tj ET Q q 0 0 0 rg BT 50.41 664.17 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.15 664.17 Td (4,872) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 664.17 Td (3,343) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 664.17 Td (1,860) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 638.33 Td (Payments to/\(fr) Tj ET Q q 0 0 0 rg BT 105.19 638.33 Td (om\) Pfizer:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 625.17 Td (Cost of products sold – Profit sharing) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 625.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.15 625.17 Td (2,314) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 625.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.15 625.17 Td (1,595) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 625.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 625.17 Td (895) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 612.17 Td (Other income \(net\) – ) Tj ET Q q 0 0 0 rg BT 124.53 612.17 Td (Amortization of deferred income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.30 612.22 Td (\(55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 612.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.30 612.22 Td (\(55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 612.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 612.17 Td (\(55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 612.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 576.60 412.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 576.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 576.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 576.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 576.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 587.6 m 511.5 587.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 576.6 m 511.5 576.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 587.6 m 575.5 587.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 576.6 m 575.5 576.6 l s BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 589.38 Td (Selected ) Tj ET Q q 0 0 0 rg BT 74.93 589.38 Td (Alliance Balance Sheet Information:) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 489.75 590.68 Td (December) Tj ET Q q 0 0 0 rg BT 524.32 590.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 579.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 473.00 579.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 537.00 579.68 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 567.17 Td (Deferred income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 567.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 567.17 Td (466) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 567.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 567.17 Td (521) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 538.53505859375 m 64.3349609375 538.53505859375 l s q 0 0 0 rg BT 36.00 540.10 Td (Gilead) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 516.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.19 516.10 Td (and ) Tj ET Q q 0 0 0 rg BT 77.69 516.10 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 107.41 516.10 Td (formed ) Tj ET Q q 0 0 0 rg BT 139.35 516.10 Td (a ) Tj ET Q q 0 0 0 rg BT 146.85 516.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 168.25 516.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 201.29 516.10 Td (in ) Tj ET Q q 0 0 0 rg BT 212.13 516.10 Td (the ) Tj ET Q q 0 0 0 rg BT 227.41 516.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 248.26 516.10 Td (and ) Tj ET Q q 0 0 0 rg BT 265.76 516.10 Td (Canada ) Tj ET Q q 0 0 0 rg BT 298.81 516.10 Td (and ) Tj ET Q q 0 0 0 rg BT 316.31 516.10 Td (another ) Tj ET Q q 0 0 0 rg BT 349.36 516.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 370.76 516.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 403.81 516.10 Td (in ) Tj ET Q q 0 0 0 rg BT 414.65 516.10 Td (Europe ) Tj ET Q q 0 0 0 rg BT 446.59 516.10 Td (to ) Tj ET Q q 0 0 0 rg BT 457.43 516.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 492.15 516.10 Td (and ) Tj ET Q q 0 0 0 rg BT 509.65 516.10 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 571.56 516.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 504.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 88.62 504.10 Td (product ) Tj ET Q q 0 0 0 rg BT 121.79 504.10 Td (named ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 151.07 504.10 Td (Atripla*,) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 186.91 504.10 Td ( ) Tj ET Q q 0 0 0 rg BT 189.54 504.10 Td (which ) Tj ET Q q 0 0 0 rg BT 216.60 504.10 Td (combines ) Tj ET Q q 0 0 0 rg BT 257.55 504.10 Td (BMS's ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 287.00 504.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.88 504.10 Td ( ) Tj ET Q q 0 0 0 rg BT 318.51 504.10 Td (with ) Tj ET Q q 0 0 0 rg BT 338.92 504.10 Td (Gilead's ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 373.89 504.10 Td (T) Tj ET Q q 0 0 0 rg BT 378.90 504.10 Td (ruvada*. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.36 504.10 Td (The ) Tj ET Q q 0 0 0 rg BT 435.53 504.10 Td (two ) Tj ET Q q 0 0 0 rg BT 453.16 504.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 474.12 504.10 Td (ventures ) Tj ET Q q 0 0 0 rg BT 510.62 504.10 Td (are ) Tj ET Q q 0 0 0 rg BT 525.46 504.10 Td (consolidated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 492.10 Td (by ) Tj ET Q q 0 0 0 rg BT 48.50 492.10 Td (Gilead.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 468.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.40 468.10 Td (December ) Tj ET Q q 0 0 0 rg BT 89.55 468.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 114.13 468.10 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 142.85 468.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 187.68 468.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 216.57 468.10 Td (participation ) Tj ET Q q 0 0 0 rg BT 269.17 468.10 Td (in ) Tj ET Q q 0 0 0 rg BT 279.02 468.10 Td (the ) Tj ET Q q 0 0 0 rg BT 293.31 468.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 313.16 468.10 Td (and ) Tj ET Q q 0 0 0 rg BT 329.67 468.10 Td (Canada ) Tj ET Q q 0 0 0 rg BT 361.73 468.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 382.13 468.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 414.19 468.10 Td (following ) Tj ET Q q 0 0 0 rg BT 455.15 468.10 Td (the ) Tj ET Q q 0 0 0 rg BT 469.43 468.10 Td (launch ) Tj ET Q q 0 0 0 rg BT 498.16 468.10 Td (of ) Tj ET Q q 0 0 0 rg BT 508.56 468.10 Td (a ) Tj ET Q q 0 0 0 rg BT 515.07 468.10 Td (generic ) Tj ET Q q 0 0 0 rg BT 546.56 468.10 Td (version ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 456.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 46.57 456.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 75.46 456.10 Td ( ) Tj ET Q q 0 0 0 rg BT 77.69 456.10 Td (by ) Tj ET Q q 0 0 0 rg BT 89.93 456.10 Td (a ) Tj ET Q q 0 0 0 rg BT 96.61 456.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 141.61 456.10 Td (in ) Tj ET Q q 0 0 0 rg BT 151.63 456.10 Td (the ) Tj ET Q q 0 0 0 rg BT 166.09 456.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 185.61 456.10 Td (As ) Tj ET Q q 0 0 0 rg BT 198.97 456.10 Td (a ) Tj ET Q q 0 0 0 rg BT 205.64 456.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 232.60 456.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 268.14 456.10 Td (income ) Tj ET Q q 0 0 0 rg BT 299.81 456.10 Td (and ) Tj ET Q q 0 0 0 rg BT 316.49 456.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 349.82 456.10 Td (receivables ) Tj ET Q q 0 0 0 rg BT 397.03 456.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 437.59 456.10 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 447.61 456.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.49 456.10 Td ( ) Tj ET Q q 0 0 0 rg BT 478.73 456.10 Td (product ) Tj ET Q q 0 0 0 rg BT 511.52 456.10 Td (held ) Tj ET Q q 0 0 0 rg BT 530.97 456.10 Td (by ) Tj ET Q q 0 0 0 rg BT 543.21 456.10 Td (the ) Tj ET Q q 0 0 0 rg BT 557.67 456.10 Td (joint ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 444.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 68.64 444.10 Td (at ) Tj ET Q q 0 0 0 rg BT 78.50 444.10 Td (December ) Tj ET Q q 0 0 0 rg BT 122.24 444.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 137.39 444.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 160.04 444.10 Td (was ) Tj ET Q q 0 0 0 rg BT 178.25 444.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 212.54 444.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 225.19 444.10 Td ($438 ) Tj ET Q q 0 0 0 rg BT 247.85 444.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 276.74 444.10 Td ( ) Tj ET Q q 0 0 0 rg BT 279.39 444.10 Td (to ) Tj ET Q q 0 0 0 rg BT 289.82 444.10 Td (reflect ) Tj ET Q q 0 0 0 rg BT 318.00 444.10 Td (the ) Tj ET Q q 0 0 0 rg BT 332.87 444.10 Td (post-termination ) Tj ET Q q 0 0 0 rg BT 401.62 444.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 430.94 444.10 Td (price. ) Tj ET Q q 0 0 0 rg BT 456.07 444.10 Td (In ) Tj ET Q q 0 0 0 rg BT 467.05 444.10 Td (addition ) Tj ET Q q 0 0 0 rg BT 502.48 444.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 526.25 444.10 Td (is ) Tj ET Q q 0 0 0 rg BT 535.58 444.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 568.22 444.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 432.10 Td (a ) Tj ET Q q 0 0 0 rg BT 43.32 432.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 58.41 432.10 Td (equal ) Tj ET Q q 0 0 0 rg BT 82.94 432.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 93.60 432.10 Td (55%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 111.93 432.10 Td ( ) Tj ET Q q 0 0 0 rg BT 114.81 432.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 126.02 432.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.36 432.10 Td ( ) Tj ET Q q 0 0 0 rg BT 162.24 432.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 182.90 432.10 Td (net ) Tj ET Q q 0 0 0 rg BT 198.00 432.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 220.32 432.10 Td (multiplied ) Tj ET Q q 0 0 0 rg BT 264.31 432.10 Td (by ) Tj ET Q q 0 0 0 rg BT 277.19 432.10 Td (the ) Tj ET Q q 0 0 0 rg BT 292.29 432.10 Td (ratio ) Tj ET Q q 0 0 0 rg BT 313.50 432.10 Td (of ) Tj ET Q q 0 0 0 rg BT 324.71 432.10 Td (the ) Tj ET Q q 0 0 0 rg BT 339.80 432.10 Td (dif) Tj ET Q q 0 0 0 rg BT 350.73 432.10 Td (ference ) Tj ET Q q 0 0 0 rg BT 383.03 432.10 Td (in ) Tj ET Q q 0 0 0 rg BT 393.69 432.10 Td (the ) Tj ET Q q 0 0 0 rg BT 408.78 432.10 Td (average ) Tj ET Q q 0 0 0 rg BT 442.75 432.10 Td (net ) Tj ET Q q 0 0 0 rg BT 457.85 432.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 487.39 432.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 514.15 432.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 525.36 432.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.70 432.10 Td ( ) Tj ET Q q 0 0 0 rg BT 561.58 432.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 420.10 Td (T) Tj ET Q q 0 0 0 rg BT 41.01 420.10 Td (ruvada*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 74.34 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 76.41 420.10 Td (to ) Tj ET Q q 0 0 0 rg BT 86.25 420.10 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 100.54 420.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 133.87 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 135.94 420.10 Td (average ) Tj ET Q q 0 0 0 rg BT 169.09 420.10 Td (net ) Tj ET Q q 0 0 0 rg BT 183.38 420.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 212.11 420.10 Td (price ) Tj ET Q q 0 0 0 rg BT 234.16 420.10 Td (in ) Tj ET Q q 0 0 0 rg BT 244.01 420.10 Td (2018. ) Tj ET Q q 0 0 0 rg BT 268.83 420.10 Td (The ) Tj ET Q q 0 0 0 rg BT 286.44 420.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 300.72 420.10 Td (is ) Tj ET Q q 0 0 0 rg BT 309.46 420.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 343.17 420.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.02 420.10 Td (35%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.35 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 373.41 420.10 Td (in ) Tj ET Q q 0 0 0 rg BT 383.26 420.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 405.33 420.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.83 420.10 Td (15%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 440.17 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 442.23 420.10 Td (in ) Tj ET Q q 0 0 0 rg BT 452.08 420.10 Td (2020, ) Tj ET Q q 0 0 0 rg BT 476.65 420.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 487.04 420.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.38 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 522.45 420.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 542.30 420.10 Td (net ) Tj ET Q q 0 0 0 rg BT 556.58 420.10 Td (sales ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 408.10 Td (multiplied ) Tj ET Q q 0 0 0 rg BT 79.07 408.10 Td (by ) Tj ET Q q 0 0 0 rg BT 91.03 408.10 Td (the ) Tj ET Q q 0 0 0 rg BT 105.21 408.10 Td (ratio ) Tj ET Q q 0 0 0 rg BT 125.50 408.10 Td (described ) Tj ET Q q 0 0 0 rg BT 165.78 408.10 Td (above. ) Tj ET Q q 0 0 0 rg BT 194.12 408.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 217.21 408.10 Td (will ) Tj ET Q q 0 0 0 rg BT 234.73 408.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 271.12 408.10 Td (to ) Tj ET Q q 0 0 0 rg BT 280.86 408.10 Td (supply ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 309.50 408.10 Td (Sustiva ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.35 408.10 Td (at ) Tj ET Q q 0 0 0 rg BT 349.53 408.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 367.60 408.10 Td (plus ) Tj ET Q q 0 0 0 rg BT 386.23 408.10 Td (a ) Tj ET Q q 0 0 0 rg BT 392.63 408.10 Td (markup ) Tj ET Q q 0 0 0 rg BT 425.14 408.10 Td (to ) Tj ET Q q 0 0 0 rg BT 434.88 408.10 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 463.50 408.10 Td (during ) Tj ET Q q 0 0 0 rg BT 491.57 408.10 Td (this ) Tj ET Q q 0 0 0 rg BT 507.98 408.10 Td (three-year ) Tj ET Q q 0 0 0 rg BT 550.47 408.10 Td (period ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 396.10 Td (unless ) Tj ET Q q 0 0 0 rg BT 63.50 396.10 Td (either ) Tj ET Q q 0 0 0 rg BT 88.76 396.10 Td (party ) Tj ET Q q 0 0 0 rg BT 111.81 396.10 Td (elects ) Tj ET Q q 0 0 0 rg BT 137.07 396.10 Td (to ) Tj ET Q q 0 0 0 rg BT 147.35 396.10 Td (terminate ) Tj ET Q q 0 0 0 rg BT 187.61 396.10 Td (the ) Tj ET Q q 0 0 0 rg BT 202.33 396.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 231.50 396.10 Td (arrangement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 372.10 Td (Prior ) Tj ET Q q 0 0 0 rg BT 58.26 372.10 Td (to ) Tj ET Q q 0 0 0 rg BT 68.31 372.10 Td (the ) Tj ET Q q 0 0 0 rg BT 82.79 372.10 Td (termination ) Tj ET Q q 0 0 0 rg BT 131.15 372.10 Td (of ) Tj ET Q q 0 0 0 rg BT 141.75 372.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 170.83 372.10 Td (participation ) Tj ET Q q 0 0 0 rg BT 223.63 372.10 Td (in ) Tj ET Q q 0 0 0 rg BT 233.67 372.10 Td (the ) Tj ET Q q 0 0 0 rg BT 248.15 372.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 268.20 372.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 288.80 372.10 Td (venture, ) Tj ET Q q 0 0 0 rg BT 323.55 372.10 Td (both ) Tj ET Q q 0 0 0 rg BT 343.59 372.10 Td (parties ) Tj ET Q q 0 0 0 rg BT 372.51 372.10 Td (actively ) Tj ET Q q 0 0 0 rg BT 406.43 372.10 Td (participated ) Tj ET Q q 0 0 0 rg BT 455.89 372.10 Td (in ) Tj ET Q q 0 0 0 rg BT 465.93 372.10 Td (a ) Tj ET Q q 0 0 0 rg BT 472.64 372.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 493.24 372.10 Td (executive ) Tj ET Q q 0 0 0 rg BT 533.81 372.10 Td (committee ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 360.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.72 360.10 Td (various ) Tj ET Q q 0 0 0 rg BT 84.45 360.10 Td (other ) Tj ET Q q 0 0 0 rg BT 107.28 360.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 147.32 360.10 Td (committees ) Tj ET Q q 0 0 0 rg BT 195.71 360.10 Td (with ) Tj ET Q q 0 0 0 rg BT 215.77 360.10 Td (direct ) Tj ET Q q 0 0 0 rg BT 240.82 360.10 Td (oversight ) Tj ET Q q 0 0 0 rg BT 280.32 360.10 Td (over ) Tj ET Q q 0 0 0 rg BT 300.37 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 314.87 360.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 353.25 360.10 Td (of ) Tj ET Q q 0 0 0 rg BT 363.87 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 378.37 360.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 398.99 360.10 Td (venture. ) Tj ET Q q 0 0 0 rg BT 433.59 360.10 Td (The ) Tj ET Q q 0 0 0 rg BT 451.42 360.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 472.04 360.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 504.31 360.10 Td (purchased ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 547.13 360.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 348.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 52.84 348.10 Td (T) Tj ET Q q 0 0 0 rg BT 57.85 348.10 Td (ruvada*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 91.18 348.10 Td ( ) Tj ET Q q 0 0 0 rg BT 93.06 348.10 Td (API ) Tj ET Q q 0 0 0 rg BT 111.58 348.10 Td (in ) Tj ET Q q 0 0 0 rg BT 121.76 348.10 Td (bulk ) Tj ET Q q 0 0 0 rg BT 141.95 348.10 Td (form ) Tj ET Q q 0 0 0 rg BT 163.79 348.10 Td (from ) Tj ET Q q 0 0 0 rg BT 185.64 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 200.26 348.10 Td (parties ) Tj ET Q q 0 0 0 rg BT 229.32 348.10 Td (and ) Tj ET Q q 0 0 0 rg BT 246.17 348.10 Td (completed ) Tj ET Q q 0 0 0 rg BT 290.22 348.10 Td (the ) Tj ET Q q 0 0 0 rg BT 304.85 348.10 Td (finishing ) Tj ET Q q 0 0 0 rg BT 342.81 348.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 353.55 348.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 386.88 348.10 Td (. ) Tj ET Q q 0 0 0 rg BT 391.61 348.10 Td (The ) Tj ET Q q 0 0 0 rg BT 409.57 348.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 430.31 348.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 462.70 348.10 Td (distributed ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 507.88 348.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 541.21 348.10 Td ( ) Tj ET Q q 0 0 0 rg BT 543.62 348.10 Td (and ) Tj ET Q q 0 0 0 rg BT 560.46 348.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.63 336.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 88.58 336.10 Td (in ) Tj ET Q q 0 0 0 rg BT 98.77 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 113.40 336.10 Td (end ) Tj ET Q q 0 0 0 rg BT 130.25 336.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 169.32 336.10 Td (product ) Tj ET Q q 0 0 0 rg BT 202.28 336.10 Td (sales. ) Tj ET Q q 0 0 0 rg BT 226.63 336.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 250.17 336.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 287.55 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 302.18 336.10 Td (bulk ) Tj ET Q q 0 0 0 rg BT 322.37 336.10 Td (efavirenz ) Tj ET Q q 0 0 0 rg BT 361.98 336.10 Td (component ) Tj ET Q q 0 0 0 rg BT 408.82 336.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 419.56 336.10 Td (Atripla) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 447.90 336.10 Td (* ) Tj ET Q q 0 0 0 rg BT 455.31 336.10 Td (as ) Tj ET Q q 0 0 0 rg BT 466.05 336.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 499.55 336.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 533.61 336.10 Td (which ) Tj ET Q q 0 0 0 rg BT 560.46 336.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 324.10 Td (based ) Tj ET Q q 0 0 0 rg BT 61.12 324.10 Td (on ) Tj ET Q q 0 0 0 rg BT 73.47 324.10 Td (the ) Tj ET Q q 0 0 0 rg BT 88.04 324.10 Td (relative ) Tj ET Q q 0 0 0 rg BT 120.37 324.10 Td (ratio ) Tj ET Q q 0 0 0 rg BT 141.04 324.10 Td (of ) Tj ET Q q 0 0 0 rg BT 151.72 324.10 Td (the ) Tj ET Q q 0 0 0 rg BT 166.29 324.10 Td (average ) Tj ET Q q 0 0 0 rg BT 199.72 324.10 Td (respective ) Tj ET Q q 0 0 0 rg BT 242.60 324.10 Td (net ) Tj ET Q q 0 0 0 rg BT 257.17 324.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 286.19 324.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 312.41 324.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 323.09 324.10 Td (T) Tj ET Q q 0 0 0 rg BT 328.10 324.10 Td (ruvada*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 361.43 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 363.78 324.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 380.57 324.10 Td (Sustiva) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.46 324.10 Td (. ) Tj ET Q q 0 0 0 rg BT 413.79 324.10 Td (Alliance ) Tj ET Q q 0 0 0 rg BT 450.01 324.10 Td (revenue ) Tj ET Q q 0 0 0 rg BT 484.01 324.10 Td (and ) Tj ET Q q 0 0 0 rg BT 500.80 324.10 Td (the ) Tj ET Q q 0 0 0 rg BT 515.36 324.10 Td (related ) Tj ET Q q 0 0 0 rg BT 544.92 324.10 Td (alliance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 312.10 Td (receivable ) Tj ET Q q 0 0 0 rg BT 79.58 312.10 Td (was ) Tj ET Q q 0 0 0 rg BT 97.63 312.10 Td (not ) Tj ET Q q 0 0 0 rg BT 112.91 312.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 159.27 312.10 Td (until ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 180.11 312.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.44 312.10 Td ( ) Tj ET Q q 0 0 0 rg BT 215.94 312.10 Td (was ) Tj ET Q q 0 0 0 rg BT 233.99 312.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 253.16 312.10 Td (to ) Tj ET Q q 0 0 0 rg BT 263.44 312.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 308.71 312.10 Td (customers.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 288.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.85 288.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 74.49 288.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 106.79 288.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.87 288.10 Td (Europe ) Tj ET Q q 0 0 0 rg BT 148.05 288.10 Td (was ) Tj ET Q q 0 0 0 rg BT 165.91 288.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 208.75 288.10 Td (for ) Tj ET Q q 0 0 0 rg BT 222.72 288.10 Td (by ) Tj ET Q q 0 0 0 rg BT 235.02 288.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 258.45 288.10 Td (and ) Tj ET Q q 0 0 0 rg BT 275.20 288.10 Td (continues ) Tj ET Q q 0 0 0 rg BT 315.83 288.10 Td (to ) Tj ET Q q 0 0 0 rg BT 325.91 288.10 Td (operate ) Tj ET Q q 0 0 0 rg BT 357.64 288.10 Td (in ) Tj ET Q q 0 0 0 rg BT 367.73 288.10 Td (a ) Tj ET Q q 0 0 0 rg BT 374.47 288.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 404.55 288.10 Td (manner ) Tj ET Q q 0 0 0 rg BT 436.84 288.10 Td (described ) Tj ET Q q 0 0 0 rg BT 477.46 288.10 Td (above ) Tj ET Q q 0 0 0 rg BT 503.65 288.10 Td (except ) Tj ET Q q 0 0 0 rg BT 532.05 288.10 Td (that ) Tj ET Q q 0 0 0 rg BT 549.35 288.10 Td (Gilead ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 276.10 Td (distributes ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 80.30 276.10 Td (Atripla*, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 118.78 276.10 Td (is ) Tj ET Q q 0 0 0 rg BT 128.08 276.10 Td (the ) Tj ET Q q 0 0 0 rg BT 142.94 276.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 181.12 276.10 Td (in ) Tj ET Q q 0 0 0 rg BT 191.54 276.10 Td (the ) Tj ET Q q 0 0 0 rg BT 206.39 276.10 Td (end ) Tj ET Q q 0 0 0 rg BT 223.47 276.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 262.76 276.10 Td (product ) Tj ET Q q 0 0 0 rg BT 295.95 276.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 318.02 276.10 Td (and ) Tj ET Q q 0 0 0 rg BT 335.10 276.10 Td (the ) Tj ET Q q 0 0 0 rg BT 349.95 276.10 Td (parties ) Tj ET Q q 0 0 0 rg BT 379.25 276.10 Td (no ) Tj ET Q q 0 0 0 rg BT 391.89 276.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 420.07 276.10 Td (coordinate ) Tj ET Q q 0 0 0 rg BT 464.91 276.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 485.88 276.10 Td (promotional ) Tj ET Q q 0 0 0 rg BT 537.40 276.10 Td (activities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 264.10 Td (The ) Tj ET Q q 0 0 0 rg BT 55.01 264.10 Td (European ) Tj ET Q q 0 0 0 rg BT 96.78 264.10 Td (joint ) Tj ET Q q 0 0 0 rg BT 118.58 264.10 Td (venture ) Tj ET Q q 0 0 0 rg BT 152.02 264.10 Td (will ) Tj ET Q q 0 0 0 rg BT 171.04 264.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 208.93 264.10 Td (until ) Tj ET Q q 0 0 0 rg BT 230.72 264.10 Td (either ) Tj ET Q q 0 0 0 rg BT 256.95 264.10 Td (party ) Tj ET Q q 0 0 0 rg BT 280.95 264.10 Td (terminates ) Tj ET Q q 0 0 0 rg BT 326.06 264.10 Td (the ) Tj ET Q q 0 0 0 rg BT 341.74 264.10 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 395.17 264.10 Td (or ) Tj ET Q q 0 0 0 rg BT 406.96 264.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.64 264.10 Td (last ) Tj ET Q q 0 0 0 rg BT 439.98 264.10 Td (patent ) Tj ET Q q 0 0 0 rg BT 467.88 264.10 Td (expires ) Tj ET Q q 0 0 0 rg BT 500.21 264.10 Td (that ) Tj ET Q q 0 0 0 rg BT 518.67 264.10 Td (allows ) Tj ET Q q 0 0 0 rg BT 548.23 264.10 Td (market ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 252.10 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 82.38 252.10 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 92.66 252.10 Td (Atripla*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 126.00 252.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.10 Td (Summarized ) Tj ET Q q 0 0 0 rg BT 89.04 228.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 126.52 228.10 Td (information ) Tj ET Q q 0 0 0 rg BT 176.23 228.10 Td (related ) Tj ET Q q 0 0 0 rg BT 205.94 228.10 Td (to ) Tj ET Q q 0 0 0 rg BT 216.21 228.10 Td (this ) Tj ET Q q 0 0 0 rg BT 233.16 228.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 266.75 228.10 Td (was ) Tj ET Q q 0 0 0 rg BT 284.80 228.10 Td (as ) Tj ET Q q 0 0 0 rg BT 295.63 228.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 193.60 348.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 193.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 193.60 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 193.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 193.60 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 193.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 193.60 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 165.60 348.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 165.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 165.60 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 165.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 165.60 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 165.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 165.60 60.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 205.60000000000002 m 448.5 205.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 205.60000000000002 m 452.5 205.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 205.60000000000002 m 512.5 205.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 205.60000000000002 m 516.5 205.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 205.60000000000002 m 576.5 205.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 193.60000000000002 m 448.5 193.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 193.60000000000002 m 512.5 193.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 193.60000000000002 m 576.5 193.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 209.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 209.68 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 209.68 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 209.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 209.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 197.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 197.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 197.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 197.68 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 184.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.64 184.33 Td (om Gilead alliances:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 170.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 170.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 170.17 Td (623) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 170.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 170.17 Td (934) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 170.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 170.17 Td (1,096) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 142.17 Td (Equity in net loss of af) Tj ET Q q 0 0 0 rg BT 129.64 142.17 Td (filiates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 142.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 142.17 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 142.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 142.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 142.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 142.17 Td (17) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 101.60 412.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 101.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 101.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 101.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 101.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 114.60000000000002 m 512.5 114.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 114.60000000000002 m 516.5 114.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 114.60000000000002 m 576.5 114.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 101.60000000000002 m 512.5 101.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 101.60000000000002 m 576.5 101.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 101.60000000000002 m 512.5 101.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 101.60000000000002 m 576.5 101.60000000000002 l s BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 118.33 Td (Selected ) Tj ET Q q 0 0 0 rg BT 75.93 118.33 Td (Alliance Balance Sheet Information:) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 490.75 118.83 Td (December) Tj ET Q q 0 0 0 rg BT 525.32 118.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 105.85 Td (Dollars ) Tj ET Q q 0 0 0 rg BT 64.55 105.85 Td (in ) Tj ET Q q 0 0 0 rg BT 72.77 105.85 Td (Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 105.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 105.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 92.17 Td (Deferred income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 92.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 92.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 92.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 92.17 Td (634) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 139 0 obj <> endobj 140 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (69) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 747.68505859375 m 67.123046875 747.68505859375 l s q 0 0 0 rg BT 36.00 749.25 Td (Otsuka) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.31 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 75.94 725.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 106.46 725.25 Td (co-promote ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 154.74 725.25 Td (Sprycel ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 186.92 725.25 Td (in ) Tj ET Q q 0 0 0 rg BT 196.88 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 211.29 725.25 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 233.76 725.25 Td (Japan ) Tj ET Q q 0 0 0 rg BT 258.72 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 275.35 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 289.75 725.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 305.27 725.25 Td (\(the ) Tj ET Q q 0 0 0 rg BT 323.01 725.25 Td (Oncology ) Tj ET Q q 0 0 0 rg BT 364.48 725.25 Td (T) Tj ET Q q 0 0 0 rg BT 369.89 725.25 Td (erritory\). ) Tj ET Q q 0 0 0 rg BT 407.89 725.25 Td (Both ) Tj ET Q q 0 0 0 rg BT 429.53 725.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 458.37 725.25 Td (actively ) Tj ET Q q 0 0 0 rg BT 492.21 725.25 Td (participate ) Tj ET Q q 0 0 0 rg BT 536.60 725.25 Td (in ) Tj ET Q q 0 0 0 rg BT 546.56 725.25 Td (various ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (governance ) Tj ET Q q 0 0 0 rg BT 84.26 713.25 Td (committees, ) Tj ET Q q 0 0 0 rg BT 135.03 713.25 Td (however) Tj ET Q q 0 0 0 rg BT 169.06 713.25 Td (, ) Tj ET Q q 0 0 0 rg BT 173.73 713.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 197.03 713.25 Td (has ) Tj ET Q q 0 0 0 rg BT 212.53 713.25 Td (control ) Tj ET Q q 0 0 0 rg BT 243.03 713.25 Td (over ) Tj ET Q q 0 0 0 rg BT 262.97 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 277.36 713.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 312.86 713.25 Td (making. ) Tj ET Q q 0 0 0 rg BT 347.52 713.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 370.82 713.25 Td (is ) Tj ET Q q 0 0 0 rg BT 379.66 713.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 427.38 713.25 Td (for ) Tj ET Q q 0 0 0 rg BT 441.21 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 455.60 713.25 Td (development ) Tj ET Q q 0 0 0 rg BT 509.43 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 526.04 713.25 Td (manufacture ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 47.08 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 62.04 701.25 Td (product ) Tj ET Q q 0 0 0 rg BT 95.34 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 112.52 701.25 Td (is ) Tj ET Q q 0 0 0 rg BT 121.94 701.25 Td (also ) Tj ET Q q 0 0 0 rg BT 140.80 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 155.76 701.25 Td (principal ) Tj ET Q q 0 0 0 rg BT 194.05 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 204.58 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 219.54 701.25 Td (end ) Tj ET Q q 0 0 0 rg BT 236.73 701.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 276.13 701.25 Td (product ) Tj ET Q q 0 0 0 rg BT 309.43 701.25 Td (sales. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 334.12 701.25 Td (Ixempra* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.18 701.25 Td (\(ixabepilone\) ) Tj ET Q q 0 0 0 rg BT 431.24 701.25 Td (was ) Tj ET Q q 0 0 0 rg BT 449.54 701.25 Td (included ) Tj ET Q q 0 0 0 rg BT 486.72 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 497.25 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 512.22 701.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 546.05 701.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 568.24 701.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 65.41 689.25 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 110.22 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 121.15 689.25 Td (that ) Tj ET Q q 0 0 0 rg BT 138.74 689.25 Td (business ) Tj ET Q q 0 0 0 rg BT 175.23 689.25 Td (in ) Tj ET Q q 0 0 0 rg BT 185.60 689.25 Td (2015. ) Tj ET Q q 0 0 0 rg BT 210.13 689.25 Td (A) Tj ET Q q 0 0 0 rg BT 216.80 689.25 Td ( ) Tj ET Q q 0 0 0 rg BT 219.39 689.25 Td (fee ) Tj ET Q q 0 0 0 rg BT 234.20 689.25 Td (is ) Tj ET Q q 0 0 0 rg BT 243.46 689.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 263.28 689.25 Td (to ) Tj ET Q q 0 0 0 rg BT 273.65 689.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 304.58 689.25 Td (based ) Tj ET Q q 0 0 0 rg BT 329.94 689.25 Td (on ) Tj ET Q q 0 0 0 rg BT 342.54 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 357.35 689.25 Td (following ) Tj ET Q q 0 0 0 rg BT 398.84 689.25 Td (percentages ) Tj ET Q q 0 0 0 rg BT 448.63 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 459.55 689.25 Td (combined ) Tj ET Q q 0 0 0 rg BT 501.58 689.25 Td (annual ) Tj ET Q q 0 0 0 rg BT 530.84 689.25 Td (net ) Tj ET Q q 0 0 0 rg BT 545.65 689.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 567.68 689.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (Sprycel ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 68.49 677.25 Td (and) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 82.92 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 85.42 677.25 Td (Ixempra* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 126.24 677.25 Td (in ) Tj ET Q q 0 0 0 rg BT 136.52 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 151.24 677.25 Td (Oncology ) Tj ET Q q 0 0 0 rg BT 193.00 677.25 Td (T) Tj ET Q q 0 0 0 rg BT 198.41 677.25 Td (erritory ) Tj ET Q q 0 0 0 rg BT 230.89 677.25 Td (\(including ) Tj ET Q q 0 0 0 rg BT 274.50 677.25 Td (post ) Tj ET Q q 0 0 0 rg BT 293.67 677.25 Td (divestiture ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 338.38 677.25 Td (Ixempra*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 376.70 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 379.20 677.25 Td (sales\) ) Tj ET Q q 0 0 0 rg BT 404.47 677.25 Td (through ) Tj ET Q q 0 0 0 rg BT 438.08 677.25 Td (2020:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 654.75 446.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 654.75 94.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 630.75 446.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 630.75 94.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 606.75 446.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 606.75 94.00 -12.00 re f /GS0 gs BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 658.70 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 504.00 658.83 Td (% of Net Sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 645.37 Td ($0 to $400 million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.80 645.37 Td (65%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 633.37 Td ($400 million to $600 million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.80 633.37 Td (12%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 621.37 Td ($600 million to $800 million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.30 621.37 Td (3%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 609.37 Td ($800 million to $1.0 billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.30 609.37 Td (2%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 597.37 Td (In excess of $1.0 billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.30 597.37 Td (1%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 571.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.63 571.25 Td (also ) Tj ET Q q 0 0 0 rg BT 78.25 571.25 Td (had ) Tj ET Q q 0 0 0 rg BT 95.20 571.25 Td (a ) Tj ET Q q 0 0 0 rg BT 102.15 571.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 147.43 571.25 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 224.34 571.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 268.50 571.25 Td (with ) Tj ET Q q 0 0 0 rg BT 288.78 571.25 Td (Otsuka, ) Tj ET Q q 0 0 0 rg BT 322.12 571.25 Td (to ) Tj ET Q q 0 0 0 rg BT 332.41 571.25 Td (co-develop ) Tj ET Q q 0 0 0 rg BT 379.34 571.25 Td (and ) Tj ET Q q 0 0 0 rg BT 396.29 571.25 Td (co-promote ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 444.90 571.25 Td (Abilify*, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.57 571.25 Td (excluding ) Tj ET Q q 0 0 0 rg BT 523.51 571.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 552.67 571.25 Td (Asian ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 559.25 Td (countries. ) Tj ET Q q 0 0 0 rg BT 77.73 559.25 Td (The ) Tj ET Q q 0 0 0 rg BT 96.04 559.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 116.60 559.25 Td (portion ) Tj ET Q q 0 0 0 rg BT 148.26 559.25 Td (of ) Tj ET Q q 0 0 0 rg BT 159.36 559.25 Td (the ) Tj ET Q q 0 0 0 rg BT 174.34 559.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 218.76 559.25 Td (expired ) Tj ET Q q 0 0 0 rg BT 251.51 559.25 Td (in ) Tj ET Q q 0 0 0 rg BT 261.45 559.25 Td (April ) Tj ET Q q 0 0 0 rg BT 285.33 559.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 308.10 559.25 Td (and ) Tj ET Q q 0 0 0 rg BT 325.31 559.25 Td (the ) Tj ET Q q 0 0 0 rg BT 340.30 559.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 356.40 559.25 Td (portion ) Tj ET Q q 0 0 0 rg BT 388.06 559.25 Td (expired ) Tj ET Q q 0 0 0 rg BT 420.81 559.25 Td (in ) Tj ET Q q 0 0 0 rg BT 431.36 559.25 Td (June ) Tj ET Q q 0 0 0 rg BT 452.46 559.25 Td (2014. ) Tj ET Q q 0 0 0 rg BT 477.73 559.25 Td (In ) Tj ET Q q 0 0 0 rg BT 488.84 559.25 Td (other ) Tj ET Q q 0 0 0 rg BT 512.15 559.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 551.58 559.25 Td (where ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 547.25 Td (we ) Tj ET Q q 0 0 0 rg BT 49.50 547.25 Td (had ) Tj ET Q q 0 0 0 rg BT 65.77 547.25 Td (the ) Tj ET Q q 0 0 0 rg BT 79.83 547.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 119.43 547.25 Td (right ) Tj ET Q q 0 0 0 rg BT 140.15 547.25 Td (to ) Tj ET Q q 0 0 0 rg BT 149.77 547.25 Td (sell ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 165.49 547.25 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 197.15 547.25 Td (, ) Tj ET Q q 0 0 0 rg BT 201.49 547.25 Td (expiration ) Tj ET Q q 0 0 0 rg BT 243.87 547.25 Td (occurred ) Tj ET Q q 0 0 0 rg BT 280.68 547.25 Td (on ) Tj ET Q q 0 0 0 rg BT 292.52 547.25 Td (a ) Tj ET Q q 0 0 0 rg BT 298.80 547.25 Td (country-by-country ) Tj ET Q q 0 0 0 rg BT 378.39 547.25 Td (basis ) Tj ET Q q 0 0 0 rg BT 400.22 547.25 Td (with ) Tj ET Q q 0 0 0 rg BT 419.84 547.25 Td (the ) Tj ET Q q 0 0 0 rg BT 433.89 547.25 Td (last ) Tj ET Q q 0 0 0 rg BT 449.62 547.25 Td (expiration ) Tj ET Q q 0 0 0 rg BT 492.00 547.25 Td (in ) Tj ET Q q 0 0 0 rg BT 501.61 547.25 Td (Canada ) Tj ET Q q 0 0 0 rg BT 533.44 547.25 Td (in ) Tj ET Q q 0 0 0 rg BT 543.05 547.25 Td (January) Tj ET Q q 0 0 0 rg BT 573.50 547.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 535.25 Td (2018.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 511.25 Td (Both ) Tj ET Q q 0 0 0 rg BT 57.47 511.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 86.14 511.25 Td (actively ) Tj ET Q q 0 0 0 rg BT 119.82 511.25 Td (participated ) Tj ET Q q 0 0 0 rg BT 169.03 511.25 Td (in ) Tj ET Q q 0 0 0 rg BT 178.83 511.25 Td (joint ) Tj ET Q q 0 0 0 rg BT 199.19 511.25 Td (executive ) Tj ET Q q 0 0 0 rg BT 239.52 511.25 Td (governance ) Tj ET Q q 0 0 0 rg BT 287.62 511.25 Td (and ) Tj ET Q q 0 0 0 rg BT 304.08 511.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 343.87 511.25 Td (committees. ) Tj ET Q q 0 0 0 rg BT 394.49 511.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 424.84 511.25 Td (was ) Tj ET Q q 0 0 0 rg BT 442.41 511.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 489.98 511.25 Td (for ) Tj ET Q q 0 0 0 rg BT 503.66 511.25 Td (providing ) Tj ET Q q 0 0 0 rg BT 544.56 511.25 Td (all ) Tj ET Q q 0 0 0 rg BT 556.58 511.25 Td (sales ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 499.25 Td (force ) Tj ET Q q 0 0 0 rg BT 58.69 499.25 Td (ef) Tj ET Q q 0 0 0 rg BT 66.28 499.25 Td (forts ) Tj ET Q q 0 0 0 rg BT 86.77 499.25 Td (in ) Tj ET Q q 0 0 0 rg BT 96.71 499.25 Td (2013, ) Tj ET Q q 0 0 0 rg BT 121.36 499.25 Td (however) Tj ET Q q 0 0 0 rg BT 155.39 499.25 Td (, ) Tj ET Q q 0 0 0 rg BT 160.05 499.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 183.33 499.25 Td (was ) Tj ET Q q 0 0 0 rg BT 201.04 499.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 248.74 499.25 Td (for ) Tj ET Q q 0 0 0 rg BT 262.56 499.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 291.92 499.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 331.84 499.25 Td (expenses ) Tj ET Q q 0 0 0 rg BT 370.09 499.25 Td (up ) Tj ET Q q 0 0 0 rg BT 382.25 499.25 Td (to ) Tj ET Q q 0 0 0 rg BT 392.19 499.25 Td (various ) Tj ET Q q 0 0 0 rg BT 423.78 499.25 Td (annual ) Tj ET Q q 0 0 0 rg BT 452.60 499.25 Td (limits. ) Tj ET Q q 0 0 0 rg BT 480.04 499.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 503.32 499.25 Td (purchased ) Tj ET Q q 0 0 0 rg BT 546.01 499.25 Td (the ) Tj ET Q q 0 0 0 rg BT 559.91 499.25 Td (API ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 487.25 Td (from ) Tj ET Q q 0 0 0 rg BT 58.03 487.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 88.95 487.25 Td (and ) Tj ET Q q 0 0 0 rg BT 105.98 487.25 Td (completed ) Tj ET Q q 0 0 0 rg BT 150.22 487.25 Td (the ) Tj ET Q q 0 0 0 rg BT 165.03 487.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 225.94 487.25 Td (of ) Tj ET Q q 0 0 0 rg BT 236.86 487.25 Td (the ) Tj ET Q q 0 0 0 rg BT 251.67 487.25 Td (product ) Tj ET Q q 0 0 0 rg BT 284.80 487.25 Td (for ) Tj ET Q q 0 0 0 rg BT 299.06 487.25 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 346.09 487.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 364.23 487.25 Td (to ) Tj ET Q q 0 0 0 rg BT 374.60 487.25 Td (third-party ) Tj ET Q q 0 0 0 rg BT 419.95 487.25 Td (customers ) Tj ET Q q 0 0 0 rg BT 463.09 487.25 Td (in ) Tj ET Q q 0 0 0 rg BT 473.46 487.25 Td (the ) Tj ET Q q 0 0 0 rg BT 488.27 487.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 508.64 487.25 Td (and ) Tj ET Q q 0 0 0 rg BT 525.67 487.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 555.47 487.25 Td (other ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 475.25 Td (countries. ) Tj ET Q q 0 0 0 rg BT 78.00 475.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 101.97 475.25 Td (provided ) Tj ET Q q 0 0 0 rg BT 140.37 475.25 Td (other ) Tj ET Q q 0 0 0 rg BT 163.76 475.25 Td (services ) Tj ET Q q 0 0 0 rg BT 198.81 475.25 Td (including ) Tj ET Q q 0 0 0 rg BT 239.43 475.25 Td (distribution, ) Tj ET Q q 0 0 0 rg BT 290.89 475.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 330.39 475.25 Td (management ) Tj ET Q q 0 0 0 rg BT 384.33 475.25 Td (and ) Tj ET Q q 0 0 0 rg BT 401.62 475.25 Td (pharmacovigilance. ) Tj ET Q q 0 0 0 rg BT 483.04 475.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 507.01 475.25 Td (was ) Tj ET Q q 0 0 0 rg BT 525.40 475.25 Td (the ) Tj ET Q q 0 0 0 rg BT 540.47 475.25 Td (principal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 463.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.50 463.25 Td (the ) Tj ET Q q 0 0 0 rg BT 65.57 463.25 Td (end ) Tj ET Q q 0 0 0 rg BT 82.85 463.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 122.35 463.25 Td (product ) Tj ET Q q 0 0 0 rg BT 155.74 463.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 178.02 463.25 Td (where ) Tj ET Q q 0 0 0 rg BT 205.29 463.25 Td (it ) Tj ET Q q 0 0 0 rg BT 213.70 463.25 Td (was ) Tj ET Q q 0 0 0 rg BT 232.09 463.25 Td (the ) Tj ET Q q 0 0 0 rg BT 247.15 463.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 287.76 463.25 Td (distributor ) Tj ET Q q 0 0 0 rg BT 332.27 463.25 Td (for ) Tj ET Q q 0 0 0 rg BT 346.77 463.25 Td (or ) Tj ET Q q 0 0 0 rg BT 357.95 463.25 Td (had ) Tj ET Q q 0 0 0 rg BT 375.23 463.25 Td (an ) Tj ET Q q 0 0 0 rg BT 387.51 463.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 428.12 463.25 Td (right ) Tj ET Q q 0 0 0 rg BT 449.85 463.25 Td (to ) Tj ET Q q 0 0 0 rg BT 460.48 463.25 Td (sell ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 477.21 463.25 Td (Abilify*. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.21 463.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 545.38 463.25 Td (was ) Tj ET Q q 0 0 0 rg BT 563.78 463.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 451.25 Td (principal ) Tj ET Q q 0 0 0 rg BT 74.40 451.25 Td (for ) Tj ET Q q 0 0 0 rg BT 88.93 451.25 Td (the ) Tj ET Q q 0 0 0 rg BT 104.01 451.25 Td (end ) Tj ET Q q 0 0 0 rg BT 121.31 451.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 160.83 451.25 Td (product ) Tj ET Q q 0 0 0 rg BT 194.24 451.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 216.54 451.25 Td (in ) Tj ET Q q 0 0 0 rg BT 227.18 451.25 Td (the ) Tj ET Q q 0 0 0 rg BT 242.26 451.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 262.90 451.25 Td (and ) Tj ET Q q 0 0 0 rg BT 280.21 451.25 Td (in ) Tj ET Q q 0 0 0 rg BT 290.85 451.25 Td (the ) Tj ET Q q 0 0 0 rg BT 305.93 451.25 Td (EU. ) Tj ET Q q 0 0 0 rg BT 323.99 451.25 Td (Alliance ) Tj ET Q q 0 0 0 rg BT 360.72 451.25 Td (revenue ) Tj ET Q q 0 0 0 rg BT 395.23 451.25 Td (was ) Tj ET Q q 0 0 0 rg BT 413.65 451.25 Td (recorded ) Tj ET Q q 0 0 0 rg BT 451.48 451.25 Td (for ) Tj ET Q q 0 0 0 rg BT 466.01 451.25 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 495.69 451.25 Td (share ) Tj ET Q q 0 0 0 rg BT 519.65 451.25 Td (of ) Tj ET Q q 0 0 0 rg BT 530.84 451.25 Td (net ) Tj ET Q q 0 0 0 rg BT 545.92 451.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 568.22 451.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 439.25 Td (third-party ) Tj ET Q q 0 0 0 rg BT 81.66 439.25 Td (customers ) Tj ET Q q 0 0 0 rg BT 125.10 439.25 Td (in ) Tj ET Q q 0 0 0 rg BT 135.78 439.25 Td (the ) Tj ET Q q 0 0 0 rg BT 150.89 439.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 171.57 439.25 Td (and ) Tj ET Q q 0 0 0 rg BT 188.90 439.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 205.13 439.25 Td (when ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 229.68 439.25 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 261.34 439.25 Td ( ) Tj ET Q q 0 0 0 rg BT 264.24 439.25 Td (was ) Tj ET Q q 0 0 0 rg BT 282.68 439.25 Td (shipped ) Tj ET Q q 0 0 0 rg BT 316.69 439.25 Td (and ) Tj ET Q q 0 0 0 rg BT 334.02 439.25 Td (all ) Tj ET Q q 0 0 0 rg BT 346.91 439.25 Td (risks ) Tj ET Q q 0 0 0 rg BT 368.70 439.25 Td (and ) Tj ET Q q 0 0 0 rg BT 386.03 439.25 Td (rewards ) Tj ET Q q 0 0 0 rg BT 420.58 439.25 Td (of ) Tj ET Q q 0 0 0 rg BT 431.81 439.25 Td (ownership ) Tj ET Q q 0 0 0 rg BT 476.36 439.25 Td (transferred ) Tj ET Q q 0 0 0 rg BT 522.56 439.25 Td (to ) Tj ET Q q 0 0 0 rg BT 533.24 439.25 Td (third-party ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 427.25 Td (customers.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 406.25 Td (Summarized ) Tj ET Q q 0 0 0 rg BT 89.04 406.25 Td (financial ) Tj ET Q q 0 0 0 rg BT 126.52 406.25 Td (information ) Tj ET Q q 0 0 0 rg BT 176.23 406.25 Td (related ) Tj ET Q q 0 0 0 rg BT 205.94 406.25 Td (to ) Tj ET Q q 0 0 0 rg BT 216.21 406.25 Td (this ) Tj ET Q q 0 0 0 rg BT 233.16 406.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 266.75 406.25 Td (was ) Tj ET Q q 0 0 0 rg BT 284.80 406.25 Td (as ) Tj ET Q q 0 0 0 rg BT 295.63 406.25 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 369.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 369.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 369.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 369.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 369.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 369.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 369.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 343.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 343.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 343.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 343.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 343.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 343.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 343.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 317.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 317.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 317.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 317.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 317.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 317.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 317.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 291.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 291.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 291.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 291.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 291.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 291.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 291.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 265.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 265.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 265.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 265.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 265.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 265.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 265.75 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 382.75 m 448.5 382.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 382.75 m 452.5 382.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 382.75 m 512.5 382.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 382.75 m 516.5 382.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 382.75 m 576.5 382.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 369.75 m 448.5 369.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 369.75 m 512.5 369.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 369.75 m 576.5 369.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 330.75 m 448.5 330.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 318.75 m 448.5 318.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 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80.53 191.65 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 156.45 191.65 Td (agreement ) Tj ET Q q 0 0 0 rg BT 199.61 191.65 Td (with ) Tj ET Q q 0 0 0 rg BT 218.90 191.65 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 239.85 191.65 Td (through ) Tj ET Q q 0 0 0 rg BT 272.47 191.65 Td (Lilly’) Tj ET Q q 0 0 0 rg BT 294.69 191.65 Td (s ) Tj ET Q q 0 0 0 rg BT 300.09 191.65 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 342.71 191.65 Td (ImClone ) Tj ET Q q 0 0 0 rg BT 379.22 191.65 Td (for ) Tj ET Q q 0 0 0 rg BT 392.39 191.65 Td (the ) Tj ET Q q 0 0 0 rg BT 406.12 191.65 Td (co-development ) Tj ET Q q 0 0 0 rg BT 472.05 191.65 Td (and ) Tj ET Q q 0 0 0 rg BT 488.00 191.65 Td (promotion ) Tj ET Q q 0 0 0 rg BT 531.18 191.65 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 541.02 191.65 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.01 191.65 Td (* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 179.65 Td (in ) Tj ET Q q 0 0 0 rg BT 46.19 179.65 Td (the ) Tj ET Q q 0 0 0 rg BT 60.81 179.65 Td (U.S., ) Tj ET Q q 0 0 0 rg BT 83.50 179.65 Td (Canada ) Tj ET Q q 0 0 0 rg BT 115.89 179.65 Td (and ) Tj ET Q q 0 0 0 rg BT 132.74 179.65 Td (Japan. ) Tj ET Q q 0 0 0 rg BT 160.41 179.65 Td (Both ) Tj ET Q q 0 0 0 rg BT 182.27 179.65 Td (parties ) Tj ET Q q 0 0 0 rg BT 211.33 179.65 Td (actively ) Tj ET Q q 0 0 0 rg BT 245.39 179.65 Td (participated ) Tj ET Q q 0 0 0 rg BT 294.99 179.65 Td (in ) Tj ET Q q 0 0 0 rg BT 305.18 179.65 Td (a ) Tj ET Q q 0 0 0 rg BT 312.03 179.65 Td (joint ) Tj ET Q q 0 0 0 rg BT 332.77 179.65 Td (executive ) Tj ET Q q 0 0 0 rg BT 373.49 179.65 Td (committee ) Tj ET Q q 0 0 0 rg BT 418.10 179.65 Td (and ) Tj ET Q q 0 0 0 rg BT 434.95 179.65 Td (various ) Tj ET Q q 0 0 0 rg BT 466.79 179.65 Td (other ) Tj ET Q q 0 0 0 rg BT 489.75 179.65 Td (operating ) Tj ET Q q 0 0 0 rg BT 529.92 179.65 Td (committees ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 167.65 Td (and ) Tj ET Q q 0 0 0 rg BT 51.72 167.65 Td (shared ) Tj ET Q q 0 0 0 rg BT 79.09 167.65 Td (responsibilities ) Tj ET Q q 0 0 0 rg BT 140.92 167.65 Td (for ) Tj ET Q q 0 0 0 rg BT 153.86 167.65 Td (research ) Tj ET Q q 0 0 0 rg BT 188.45 167.65 Td (and ) Tj ET Q q 0 0 0 rg BT 204.16 167.65 Td (development ) Tj ET Q q 0 0 0 rg BT 257.09 167.65 Td (using ) Tj ET Q q 0 0 0 rg BT 280.04 167.65 Td (resources ) Tj ET Q q 0 0 0 rg BT 319.08 167.65 Td (in ) Tj ET Q q 0 0 0 rg BT 328.13 167.65 Td (their ) Tj ET Q q 0 0 0 rg BT 347.74 167.65 Td (own ) Tj ET Q q 0 0 0 rg BT 366.24 167.65 Td (infrastructures. ) Tj ET Q q 0 0 0 rg BT 427.77 167.65 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 448.49 167.65 Td (manufactured ) Tj ET Q q 0 0 0 rg BT 504.74 167.65 Td (bulk ) Tj ET Q q 0 0 0 rg BT 523.80 167.65 Td (requirements ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 155.65 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 50.49 155.65 Td (Erbitux*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.48 155.65 Td ( ) Tj ET Q q 0 0 0 rg BT 88.31 155.65 Td (in ) Tj ET Q q 0 0 0 rg BT 98.91 155.65 Td (its 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BT 59.99 143.65 Td (had ) Tj ET Q q 0 0 0 rg BT 77.29 143.65 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 117.92 143.65 Td (distribution ) Tj ET Q q 0 0 0 rg BT 166.89 143.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 192.54 143.65 Td (in ) Tj ET Q q 0 0 0 rg BT 203.18 143.65 Td (North ) Tj ET Q q 0 0 0 rg BT 228.74 143.65 Td (America ) Tj ET Q q 0 0 0 rg BT 266.03 143.65 Td (and ) Tj ET Q q 0 0 0 rg BT 283.33 143.65 Td (was ) Tj ET Q q 0 0 0 rg BT 301.75 143.65 Td (responsible ) Tj ET Q q 0 0 0 rg BT 350.16 143.65 Td (for ) Tj ET Q q 0 0 0 rg BT 364.68 143.65 Td (promotional ) Tj ET Q q 0 0 0 rg BT 416.43 143.65 Td (ef) Tj ET Q q 0 0 0 rg BT 424.01 143.65 Td (forts ) Tj ET Q q 0 0 0 rg BT 445.21 143.65 Td (in ) Tj ET Q q 0 0 0 rg BT 455.85 143.65 Td (North ) Tj ET Q q 0 0 0 rg BT 481.41 143.65 Td (America ) Tj ET Q q 0 0 0 rg BT 518.70 143.65 Td (although ) Tj ET Q q 0 0 0 rg BT 556.56 143.65 Td (Lilly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 131.65 Td (had ) Tj ET Q q 0 0 0 rg BT 52.72 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Td (in ) Tj ET Q q 0 0 0 rg BT 516.49 131.65 Td (North ) Tj ET Q q 0 0 0 rg BT 541.60 131.65 Td (America ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 119.65 Td (and ) Tj ET Q q 0 0 0 rg BT 53.26 119.65 Td (paid ) Tj ET Q q 0 0 0 rg BT 73.30 119.65 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 95.57 119.65 Td (a ) Tj ET Q q 0 0 0 rg BT 102.84 119.65 Td (distribution ) Tj ET Q q 0 0 0 rg BT 151.77 119.65 Td (fee ) Tj ET Q q 0 0 0 rg BT 166.81 119.65 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 181.29 119.65 Td (39%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 199.62 119.65 Td ( ) Tj ET Q q 0 0 0 rg BT 202.45 119.65 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 213.60 119.65 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 243.60 119.65 Td (* ) Tj ET Q q 0 0 0 rg BT 251.42 119.65 Td (net ) Tj ET Q q 0 0 0 rg BT 266.46 119.65 Td (sales ) Tj ET Q q 0 0 0 rg BT 288.72 119.65 Td (in ) Tj ET Q q 0 0 0 rg BT 299.33 119.65 Td (North ) Tj ET Q q 0 0 0 rg BT 324.86 119.65 Td (America ) Tj ET Q q 0 0 0 rg BT 362.11 119.65 Td (plus ) Tj ET Q q 0 0 0 rg BT 381.60 119.65 Td (a ) Tj ET Q q 0 0 0 rg BT 388.87 119.65 Td (share ) Tj ET Q q 0 0 0 rg BT 412.79 119.65 Td (of ) Tj ET Q q 0 0 0 rg BT 423.94 119.65 Td (certain ) Tj ET Q q 0 0 0 rg BT 453.97 119.65 Td (royalties ) Tj ET Q q 0 0 0 rg BT 491.23 119.65 Td (paid ) Tj ET Q q 0 0 0 rg BT 511.27 119.65 Td (by ) Tj ET Q q 0 0 0 rg BT 524.09 119.65 Td (Lilly) Tj ET Q q 0 0 0 rg BT 542.89 119.65 Td (. ) Tj ET Q q 0 0 0 rg BT 548.21 119.65 Td (BMS’) Tj ET Q q 0 0 0 rg BT 572.11 119.65 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 107.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 61.28 107.65 Td (and ) Tj ET Q q 0 0 0 rg BT 78.22 107.65 Td (obligations ) Tj ET Q q 0 0 0 rg BT 125.16 107.65 Td (with ) Tj ET Q q 0 0 0 rg BT 145.44 107.65 Td (respect ) Tj ET Q q 0 0 0 rg BT 176.25 107.65 Td (to ) Tj ET Q q 0 0 0 rg BT 186.53 107.65 Td (the ) Tj ET Q q 0 0 0 rg BT 201.25 107.65 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 278.16 107.65 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 288.99 107.65 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.98 107.65 Td (* ) Tj ET Q q 0 0 0 rg BT 326.48 107.65 Td (in ) Tj ET Q q 0 0 0 rg BT 336.76 107.65 Td (North ) Tj ET Q q 0 0 0 rg BT 362.04 107.65 Td (America ) Tj ET Q q 0 0 0 rg BT 398.96 107.65 Td (would ) Tj ET Q q 0 0 0 rg BT 426.46 107.65 Td (have ) Tj ET Q q 0 0 0 rg BT 447.84 107.65 Td (expired ) Tj ET Q q 0 0 0 rg BT 480.33 107.65 Td (in ) Tj ET Q q 0 0 0 rg BT 490.60 107.65 Td (September ) Tj ET Q q 0 0 0 rg BT 535.87 107.65 Td (2018.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 83.65 Td (In ) Tj ET Q q 0 0 0 rg BT 47.41 83.65 Td (October ) Tj ET Q q 0 0 0 rg BT 82.70 83.65 Td (2015, ) Tj ET Q q 0 0 0 rg BT 108.29 83.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 132.49 83.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 178.88 83.65 Td (its ) Tj ET Q q 0 0 0 rg BT 191.42 83.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 217.28 83.65 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 228.14 83.65 Td (Erbitux*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.13 83.65 Td ( ) Tj ET Q q 0 0 0 rg BT 266.22 83.65 Td (in ) Tj ET Q q 0 0 0 rg BT 277.08 83.65 Td (North ) Tj ET Q q 0 0 0 rg BT 302.81 83.65 Td (America ) Tj ET Q q 0 0 0 rg BT 340.32 83.65 Td (to ) Tj ET Q q 0 0 0 rg BT 351.18 83.65 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 373.71 83.65 Td (in ) Tj ET Q q 0 0 0 rg BT 384.57 83.65 Td (exchange ) Tj ET Q q 0 0 0 rg BT 425.41 83.65 Td (for ) Tj ET Q q 0 0 0 rg BT 440.15 83.65 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 488.77 83.65 Td (royalties ) Tj ET Q q 0 0 0 rg BT 526.29 83.65 Td (as ) Tj ET Q q 0 0 0 rg BT 537.70 83.65 Td (described ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 71.65 Td (below) Tj ET Q q 0 0 0 rg BT 59.79 71.65 Td (. ) Tj ET Q q 0 0 0 rg BT 64.64 71.65 Td (The ) Tj ET Q q 0 0 0 rg BT 82.73 71.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 128.58 71.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 153.89 71.65 Td (include, ) Tj ET Q q 0 0 0 rg BT 188.37 71.65 Td (but ) Tj ET Q q 0 0 0 rg BT 203.68 71.65 Td (are ) Tj ET Q q 0 0 0 rg BT 218.43 71.65 Td (not ) Tj ET Q q 0 0 0 rg BT 233.75 71.65 Td (limited ) Tj ET Q q 0 0 0 rg BT 264.62 71.65 Td (to, ) Tj ET Q q 0 0 0 rg BT 277.43 71.65 Td (full ) Tj ET Q q 0 0 0 rg BT 293.86 71.65 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 370.81 71.65 Td (and ) Tj ET Q q 0 0 0 rg BT 387.78 71.65 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 448.63 71.65 Td (responsibilities. ) Tj ET Q q 0 0 0 rg BT 514.04 71.65 Td (The ) Tj ET Q q 0 0 0 rg BT 532.13 71.65 Td (transaction ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 59.65 Td (was ) Tj ET Q q 0 0 0 rg BT 53.94 59.65 Td (accounted ) Tj ET Q q 0 0 0 rg BT 96.86 59.65 Td (for ) Tj ET Q q 0 0 0 rg BT 110.91 59.65 Td (as ) Tj ET Q q 0 0 0 rg BT 121.63 59.65 Td (a ) Tj ET Q q 0 0 0 rg BT 128.46 59.65 Td (business ) Tj ET Q q 0 0 0 rg BT 164.75 59.65 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 209.35 59.65 Td (and ) Tj ET Q q 0 0 0 rg BT 226.18 59.65 Td (resulted ) Tj ET Q q 0 0 0 rg BT 260.22 59.65 Td (in ) Tj ET Q q 0 0 0 rg BT 270.39 59.65 Td (a ) Tj ET Q q 0 0 0 rg BT 277.22 59.65 Td (non-cash ) Tj ET Q q 0 0 0 rg BT 315.71 59.65 Td (char) Tj ET Q q 0 0 0 rg BT 332.73 59.65 Td (ge ) Tj ET Q q 0 0 0 rg BT 344.56 59.65 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 355.28 59.65 Td ($171 ) Tj ET Q q 0 0 0 rg BT 377.67 59.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.56 59.65 Td ( ) Tj ET Q q 0 0 0 rg BT 408.95 59.65 Td (for ) Tj ET Q q 0 0 0 rg BT 423.00 59.65 Td (intangible ) Tj ET Q q 0 0 0 rg BT 465.38 59.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 491.10 59.65 Td (directly ) Tj ET Q q 0 0 0 rg BT 524.04 59.65 Td (related ) Tj ET Q q 0 0 0 rg BT 553.63 59.65 Td (to ) Tj ET Q q 0 0 0 rg BT 563.80 59.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 47.65 Td (business ) Tj ET Q q 0 0 0 rg BT 72.39 47.65 Td (and ) Tj ET Q q 0 0 0 rg BT 89.33 47.65 Td (an ) Tj ET Q q 0 0 0 rg BT 101.27 47.65 Td (allocation ) Tj ET Q q 0 0 0 rg BT 143.20 47.65 Td (of ) Tj ET Q q 0 0 0 rg BT 154.03 47.65 Td (goodwill. ) Tj ET Q endstream endobj 141 0 obj <> endobj 142 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (70) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.89 737.10 Td (will ) Tj ET Q q 0 0 0 rg BT 78.22 737.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 109.85 737.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 147.05 737.10 Td (through ) Tj ET Q q 0 0 0 rg BT 180.93 737.10 Td (September ) Tj ET Q q 0 0 0 rg BT 226.46 737.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 251.73 737.10 Td (which ) Tj ET Q q 0 0 0 rg BT 278.93 737.10 Td (are ) Tj ET Q q 0 0 0 rg BT 293.91 737.10 Td (included ) Tj ET Q q 0 0 0 rg BT 331.11 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 341.66 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 364.97 737.10 Td (income ) Tj ET Q q 0 0 0 rg BT 397.18 737.10 Td (when ) Tj ET Q q 0 0 0 rg BT 421.61 737.10 Td (earned. ) Tj ET Q q 0 0 0 rg BT 453.32 737.10 Td (The ) Tj ET Q q 0 0 0 rg BT 471.63 737.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 502.73 737.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 524.37 737.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 568.23 737.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (North ) Tj ET Q q 0 0 0 rg BT 61.26 725.10 Td (America ) Tj ET Q q 0 0 0 rg BT 98.17 725.10 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 112.85 725.10 Td (38%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 131.18 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 133.66 725.10 Td (on ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 146.14 725.10 Td (Erbitux*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 181.14 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 183.62 725.10 Td (net ) Tj ET Q q 0 0 0 rg BT 198.31 725.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 220.23 725.10 Td (up ) Tj ET Q q 0 0 0 rg BT 232.71 725.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 242.97 725.10 Td ($165 ) Tj ET Q q 0 0 0 rg BT 265.45 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 294.34 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 296.82 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 307.08 725.10 Td (2015, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.06 725.10 Td ($650 ) Tj ET Q q 0 0 0 rg BT 354.53 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.43 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 385.91 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 396.16 725.10 Td (2016, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.14 725.10 Td ($650 ) Tj ET Q q 0 0 0 rg BT 443.62 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.51 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 474.99 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 485.25 725.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 507.73 725.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 524.65 725.10 Td ($480 ) Tj ET Q q 0 0 0 rg BT 547.13 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.37 713.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 71.45 713.10 Td (plus ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 90.71 713.10 Td (20%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 109.04 713.10 Td ( ) Tj ET Q q 0 0 0 rg BT 111.63 713.10 Td (on ) Tj ET Q q 0 0 0 rg BT 124.21 713.10 Td (net ) Tj ET Q q 0 0 0 rg BT 139.02 713.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 161.04 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 171.41 713.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 200.09 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 211.01 713.10 Td (those ) Tj ET Q q 0 0 0 rg BT 234.71 713.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 271.18 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 281.54 713.10 Td (each ) Tj ET Q q 0 0 0 rg BT 302.45 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 313.36 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 328.17 713.10 Td (respective ) Tj ET Q q 0 0 0 rg BT 371.29 713.10 Td (years. ) Tj ET Q q 0 0 0 rg BT 397.47 713.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 437.83 713.10 Td (earned ) Tj ET Q q 0 0 0 rg BT 467.06 713.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.08 713.10 Td ($207 ) Tj ET Q q 0 0 0 rg BT 511.67 713.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 540.56 713.10 Td ( ) Tj ET Q q 0 0 0 rg BT 543.15 713.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.51 713.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.51 713.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td ($227 ) Tj ET Q q 0 0 0 rg BT 58.50 701.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.39 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 89.89 701.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.17 701.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 120.17 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 122.67 701.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.61 701.10 Td ($56 ) Tj ET Q q 0 0 0 rg BT 157.11 701.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 186.00 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 188.50 701.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 198.78 701.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 218.78 701.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.11 677.10 Td (shared ) Tj ET Q q 0 0 0 rg BT 89.20 677.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 114.96 677.10 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 125.73 677.10 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 155.72 677.10 Td (* ) Tj ET Q q 0 0 0 rg BT 163.71 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 174.48 677.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 200.23 677.10 Td (under ) Tj ET Q q 0 0 0 rg BT 225.99 677.10 Td (an ) Tj ET Q q 0 0 0 rg BT 238.41 677.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 283.04 677.10 Td (with ) Tj ET Q q 0 0 0 rg BT 303.81 677.10 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 326.24 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 343.66 677.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 372.75 677.10 Td (KGaA) Tj ET Q q 0 0 0 rg BT 398.30 677.10 Td ( ) Tj ET Q q 0 0 0 rg BT 401.29 677.10 Td (and ) Tj ET Q q 0 0 0 rg BT 418.71 677.10 Td (received ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.56 677.10 Td (50%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.89 677.10 Td ( ) Tj ET Q q 0 0 0 rg BT 476.88 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 488.20 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 503.40 677.10 Td (pretax ) Tj ET Q q 0 0 0 rg BT 531.38 677.10 Td (profit ) Tj ET Q q 0 0 0 rg BT 556.58 677.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 65.09 665.10 Td (KGaA) Tj ET Q q 0 0 0 rg BT 90.09 665.10 Td (’) Tj ET Q q 0 0 0 rg BT 92.86 665.10 Td (s ) Tj ET Q q 0 0 0 rg BT 99.75 665.10 Td (net ) Tj ET Q q 0 0 0 rg BT 114.96 665.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 137.39 665.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 148.71 665.10 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 178.71 665.10 Td (* ) Tj ET Q q 0 0 0 rg BT 186.70 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 197.47 665.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 223.23 665.10 Td (which ) Tj ET Q q 0 0 0 rg BT 250.66 665.10 Td (was ) Tj ET Q q 0 0 0 rg BT 269.20 665.10 Td (further ) Tj ET Q q 0 0 0 rg BT 299.40 665.10 Td (shared ) Tj ET Q q 0 0 0 rg BT 328.49 665.10 Td (equally ) Tj ET Q q 0 0 0 rg BT 360.92 665.10 Td (with ) Tj ET Q q 0 0 0 rg BT 381.69 665.10 Td (Lilly) Tj ET Q q 0 0 0 rg BT 400.48 665.10 Td (. ) Tj ET Q q 0 0 0 rg BT 405.98 665.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 430.09 665.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 476.39 665.10 Td (its ) Tj ET Q q 0 0 0 rg BT 488.83 665.10 Td (co-commercialization ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 61.93 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 72.87 653.10 Td (Japan ) Tj ET Q q 0 0 0 rg BT 98.79 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 109.72 653.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 138.97 653.10 Td (KGaA) Tj ET Q q 0 0 0 rg BT 164.53 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 167.68 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 178.61 653.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 201.77 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 212.70 653.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 253.61 653.10 Td (for ) Tj ET Q q 0 0 0 rg BT 268.42 653.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 317.11 653.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 354.70 653.10 Td (through ) Tj ET Q q 0 0 0 rg BT 388.96 653.10 Td (2032 ) Tj ET Q q 0 0 0 rg BT 412.12 653.10 Td (which ) Tj ET Q q 0 0 0 rg BT 439.71 653.10 Td (is ) Tj ET Q q 0 0 0 rg BT 449.54 653.10 Td (included ) Tj ET Q q 0 0 0 rg BT 487.12 653.10 Td (in ) Tj ET Q q 0 0 0 rg BT 498.06 653.10 Td (other ) Tj ET Q q 0 0 0 rg BT 521.76 653.10 Td (income ) Tj ET Q q 0 0 0 rg BT 554.34 653.10 Td (when ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (earned. ) Tj ET Q q 0 0 0 rg BT 67.45 641.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 107.52 641.10 Td (earned ) Tj ET Q q 0 0 0 rg BT 136.46 641.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 158.19 641.10 Td ($17 ) Tj ET Q q 0 0 0 rg BT 175.49 641.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 204.38 641.10 Td ( ) Tj ET Q q 0 0 0 rg BT 206.68 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 216.76 641.10 Td (2017, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 241.56 641.10 Td ($19 ) Tj ET Q q 0 0 0 rg BT 258.86 641.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 287.75 641.10 Td ( ) Tj ET Q q 0 0 0 rg BT 290.05 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 300.13 641.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 322.43 641.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.17 641.10 Td ($14 ) Tj ET Q q 0 0 0 rg BT 356.47 641.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 385.36 641.10 Td ( ) Tj ET Q q 0 0 0 rg BT 387.66 641.10 Td (in ) Tj ET Q q 0 0 0 rg BT 397.74 641.10 Td (2015. ) Tj ET Q q 0 0 0 rg BT 422.03 641.10 Td (As ) Tj ET Q q 0 0 0 rg BT 435.44 641.10 Td (a ) Tj ET Q q 0 0 0 rg BT 442.18 641.10 Td (result ) Tj ET Q q 0 0 0 rg BT 466.70 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 477.33 641.10 Td (the ) Tj ET Q q 0 0 0 rg BT 491.84 641.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 529.14 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 539.26 641.10 Td (ASC ) Tj ET Q q 0 0 0 rg BT 561.01 641.10 Td (606 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td (in ) Tj ET Q q 0 0 0 rg BT 45.66 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 59.75 629.10 Td (first ) Tj ET Q q 0 0 0 rg BT 77.74 629.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 107.94 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 118.15 629.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 142.53 629.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 182.73 629.10 Td (future ) Tj ET Q q 0 0 0 rg BT 208.49 629.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 244.80 629.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 281.67 629.10 Td (from ) Tj ET Q q 0 0 0 rg BT 302.99 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 317.09 629.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 349.51 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 359.72 629.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 384.37 629.10 Td (to ) Tj ET Q q 0 0 0 rg BT 394.03 629.10 Td (Merck ) Tj ET Q q 0 0 0 rg BT 422.01 629.10 Td (KGaA) Tj ET Q q 0 0 0 rg BT 447.56 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 449.44 629.10 Td (will ) Tj ET Q q 0 0 0 rg BT 466.88 629.10 Td (be ) Tj ET Q q 0 0 0 rg BT 478.20 629.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 515.05 629.10 Td (as ) Tj ET Q q 0 0 0 rg BT 525.26 629.10 Td (a ) Tj ET Q q 0 0 0 rg BT 531.58 629.10 Td (cumulative ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (ef) Tj ET Q q 0 0 0 rg BT 43.59 617.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 61.07 617.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 107.46 617.10 Td (in ) Tj ET Q q 0 0 0 rg BT 117.73 617.10 Td (retained ) Tj ET Q q 0 0 0 rg BT 152.44 617.10 Td (earnings. ) Tj ET Q q 0 0 0 rg BT 191.31 617.10 Td (Subsequent ) Tj ET Q q 0 0 0 rg BT 239.92 617.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 274.63 617.10 Td (in ) Tj ET Q q 0 0 0 rg BT 284.91 617.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 324.62 617.10 Td (will ) Tj ET Q q 0 0 0 rg BT 342.67 617.10 Td (be ) Tj ET Q q 0 0 0 rg BT 354.61 617.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 392.09 617.10 Td (in ) Tj ET Q q 0 0 0 rg BT 402.37 617.10 Td (other ) Tj ET Q q 0 0 0 rg BT 425.41 617.10 Td (income ) Tj ET Q q 0 0 0 rg BT 457.35 617.10 Td (\(net\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.10 Td (Summarized ) Tj ET Q q 0 0 0 rg BT 89.04 593.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 126.52 593.10 Td (information ) Tj ET Q q 0 0 0 rg BT 176.23 593.10 Td (related ) Tj ET Q q 0 0 0 rg BT 205.94 593.10 Td (to ) Tj ET Q q 0 0 0 rg BT 216.21 593.10 Td (this ) Tj ET Q q 0 0 0 rg BT 233.16 593.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 266.75 593.10 Td (was ) Tj ET Q q 0 0 0 rg BT 284.80 593.10 Td (as ) Tj ET Q q 0 0 0 rg BT 295.63 593.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 556.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 556.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 556.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 556.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 556.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 556.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 556.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 528.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 528.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 528.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 528.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 528.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 528.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 528.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 502.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 502.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 502.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 502.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 476.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 476.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 476.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 476.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 450.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 450.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 450.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 450.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 569.6 m 448.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 569.6 m 452.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 569.6 m 512.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 569.6 m 516.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 569.6 m 576.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 556.6 m 448.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 556.6 m 512.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 556.6 m 576.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 556.6 m 448.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 556.6 m 512.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 556.6 m 576.5 556.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 515.6 m 448.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 503.6 m 448.5 503.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 501.6 m 448.5 501.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 515.6 m 512.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 503.6 m 512.5 503.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 501.6 m 512.5 501.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 515.6 m 576.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 503.6 m 576.5 503.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 501.6 m 576.5 501.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 573.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 573.83 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 573.83 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 573.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 573.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 560.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 560.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 560.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 560.83 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 547.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.64 547.33 Td (om Lilly alliance:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 534.17 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 533.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 533.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 533.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 533.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 533.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 533.27 Td (492) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 519.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 519.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 519.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 519.17 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 506.17 Td (T) Tj ET Q q 0 0 0 rg BT 50.41 506.17 Td (otal revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 506.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 506.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 506.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 506.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 506.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 506.17 Td (501) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 480.17 Td (Cost of products sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 480.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 480.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 480.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 480.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 480.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 480.17 Td (261) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 454.17 Td (Other income \(net\):) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 441.17 Td (Royalties) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.30 441.22 Td (\(224) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 441.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.30 441.22 Td (\(246) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 441.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 441.17 Td (\(70) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 441.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 428.17 Td (Divestiture loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 428.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 428.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 428.17 Td (171) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 399.53505859375 m 90.4287109375 399.53505859375 l s q 0 0 0 rg BT 36.00 401.10 Td (AstraZeneca) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (Prior ) Tj ET Q q 0 0 0 rg BT 59.25 377.10 Td (to ) Tj ET Q q 0 0 0 rg BT 70.27 377.10 Td (the ) Tj ET Q q 0 0 0 rg BT 85.74 377.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 121.75 377.10 Td (business ) Tj ET Q q 0 0 0 rg BT 158.89 377.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 204.34 377.10 Td (discussed ) Tj ET Q q 0 0 0 rg BT 245.92 377.10 Td (below) Tj ET Q q 0 0 0 rg BT 269.71 377.10 Td (, ) Tj ET Q q 0 0 0 rg BT 275.46 377.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 299.83 377.10 Td (had ) Tj ET Q q 0 0 0 rg BT 317.51 377.10 Td (an ) Tj ET Q q 0 0 0 rg BT 330.20 377.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 364.54 377.10 Td (with ) Tj ET Q q 0 0 0 rg BT 384.84 377.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 438.61 377.10 Td (consisting ) Tj ET Q q 0 0 0 rg BT 482.42 377.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.99 377.10 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.98 377.10 Td ( ) Tj ET Q q 0 0 0 rg BT 517.23 377.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 563.24 377.10 Td (co-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 365.10 Td (development ) Tj ET Q q 0 0 0 rg BT 89.94 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 106.67 365.10 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 183.37 365.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 231.19 365.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 268.47 365.10 Td (\(1\) ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 282.42 365.10 Td (Onglyza*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.75 365.10 Td ( ) Tj ET Q q 0 0 0 rg BT 323.04 365.10 Td (and ) Tj ET Q q 0 0 0 rg BT 339.76 365.10 Td (related ) Tj ET Q q 0 0 0 rg BT 369.26 365.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 421.54 365.10 Td (products ) Tj ET Q q 0 0 0 rg BT 458.27 365.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 477.23 365.10 Td (under ) Tj ET Q q 0 0 0 rg BT 502.28 365.10 Td (various ) Tj ET Q q 0 0 0 rg BT 534.01 365.10 Td (names, ) Tj ET Q q 0 0 0 rg BT 564.35 365.10 Td (\(2\) ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (Farxiga* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 75.61 353.10 Td (and ) Tj ET Q q 0 0 0 rg BT 92.44 353.10 Td (related ) Tj ET Q q 0 0 0 rg BT 122.04 353.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 174.42 353.10 Td (products ) Tj ET Q q 0 0 0 rg BT 211.25 353.10 Td (and, ) Tj ET Q q 0 0 0 rg BT 230.58 353.10 Td (\(3\) ) Tj ET Q q 0 0 0 rg BT 244.63 353.10 Td (beginning ) Tj ET Q q 0 0 0 rg BT 287.02 353.10 Td (in ) Tj ET Q q 0 0 0 rg BT 296.66 353.10 Td (August ) Tj ET Q q 0 0 0 rg BT 327.95 353.10 Td (2012 ) Tj ET Q q 0 0 0 rg BT 350.34 353.10 Td (after ) Tj ET Q q 0 0 0 rg BT 371.05 353.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 400.26 353.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 446.53 353.10 Td (of ) Tj ET Q q 0 0 0 rg BT 456.73 353.10 Td (Amylin, ) Tj ET Q q 0 0 0 rg BT 491.65 353.10 Td (Amylin's ) Tj ET Q q 0 0 0 rg BT 530.29 353.10 Td (portfolio ) Tj ET Q q 0 0 0 rg BT 567.68 353.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.10 Td (products ) Tj ET Q q 0 0 0 rg BT 73.25 341.10 Td (including ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 113.83 341.10 Td (Bydur) Tj ET Q q 0 0 0 rg BT 137.90 341.10 Td (eon*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.34 341.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 162.65 341.10 Td (Byetta*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 193.19 341.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 198.51 341.10 Td (Symlin* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 233.53 341.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 250.78 341.10 Td (Myalept*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.55 341.10 Td (, ) Tj ET Q q 0 0 0 rg BT 293.86 341.10 Td (as ) Tj ET Q q 0 0 0 rg BT 305.00 341.10 Td (well ) Tj ET Q q 0 0 0 rg BT 325.03 341.10 Td (as ) Tj ET Q q 0 0 0 rg BT 336.17 341.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 366.18 341.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 392.33 341.10 Td (owned ) Tj ET Q q 0 0 0 rg BT 421.80 341.10 Td (by ) Tj ET Q q 0 0 0 rg BT 433.99 341.10 Td (Amylin, ) Tj ET Q q 0 0 0 rg BT 469.86 341.10 Td (including ) Tj ET Q q 0 0 0 rg BT 510.44 341.10 Td (a ) Tj ET Q q 0 0 0 rg BT 517.69 341.10 Td (manufacturing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 66.82 329.10 Td (located ) Tj ET Q q 0 0 0 rg BT 98.19 329.10 Td (in ) Tj ET Q q 0 0 0 rg BT 108.29 329.10 Td (W) Tj ET Q q 0 0 0 rg BT 116.93 329.10 Td (est ) Tj ET Q q 0 0 0 rg BT 130.54 329.10 Td (Chester) Tj ET Q q 0 0 0 rg BT 160.68 329.10 Td (, ) Tj ET Q q 0 0 0 rg BT 165.68 329.10 Td (Ohio.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.61 305.10 Td (February ) Tj ET Q q 0 0 0 rg BT 87.00 305.10 Td (2014, ) Tj ET Q q 0 0 0 rg BT 112.78 305.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 137.19 305.10 Td (and ) Tj ET Q q 0 0 0 rg BT 154.18 305.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 207.99 305.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 254.03 305.10 Td (their ) Tj ET Q q 0 0 0 rg BT 275.64 305.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 310.01 305.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 358.83 305.10 Td (and ) Tj ET Q q 0 0 0 rg BT 376.55 305.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 400.96 305.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 420.91 305.10 Td (to ) Tj ET Q q 0 0 0 rg BT 431.25 305.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 485.06 305.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 538.89 305.10 Td (all ) Tj ET Q q 0 0 0 rg BT 552.17 305.10 Td (of ) Tj ET Q q 0 0 0 rg BT 563.78 305.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 70.15 293.10 Td (business ) Tj ET Q q 0 0 0 rg BT 105.43 293.10 Td (comprising ) Tj ET Q q 0 0 0 rg BT 151.82 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 165.42 293.10 Td (alliance. ) Tj ET Q q 0 0 0 rg BT 200.30 293.10 Td (The ) Tj ET Q q 0 0 0 rg BT 217.24 293.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 260.84 293.10 Td (included ) Tj ET Q q 0 0 0 rg BT 296.66 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 310.27 293.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 336.65 293.10 Td (of ) Tj ET Q q 0 0 0 rg BT 346.06 293.10 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 378.00 293.10 Td (and ) Tj ET Q q 0 0 0 rg BT 393.83 293.10 Td (the ) Tj ET Q q 0 0 0 rg BT 407.44 293.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 443.82 293.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 475.75 293.10 Td (of ) Tj ET Q q 0 0 0 rg BT 485.47 293.10 Td (its ) Tj ET Q q 0 0 0 rg BT 496.31 293.10 Td (Ohio ) Tj ET Q q 0 0 0 rg BT 517.69 293.10 Td (manufacturing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.10 Td (facility; ) Tj ET Q q 0 0 0 rg BT 68.99 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 83.11 281.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 129.43 281.10 Td (property ) Tj ET Q q 0 0 0 rg BT 165.20 281.10 Td (related ) Tj ET Q q 0 0 0 rg BT 194.30 281.10 Td (to) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 202.08 281.10 Td ( ) Tj ET Q q 0 0 0 rg BT 203.97 281.10 Td (Onglyza*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 242.30 281.10 Td ( ) Tj ET Q q 0 0 0 rg BT 244.20 281.10 Td (and) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 258.64 281.10 Td ( ) Tj ET Q q 0 0 0 rg BT 260.53 281.10 Td (Farxiga*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 297.75 281.10 Td ( ) Tj ET Q q 0 0 0 rg BT 299.65 281.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 342.65 281.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 371.36 281.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 402.69 281.10 Td (in ) Tj ET Q q 0 0 0 rg BT 412.36 281.10 Td (the ) Tj ET Q q 0 0 0 rg BT 426.47 281.10 Td (out-licensing ) Tj ET Q q 0 0 0 rg BT 480.58 281.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 524.12 281.10 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 537.68 281.10 Td (Onglyza*) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.10 Td (in ) Tj ET Q q 0 0 0 rg BT 47.04 269.10 Td (Japan\); ) Tj ET Q q 0 0 0 rg BT 79.18 269.10 Td (and ) Tj ET Q q 0 0 0 rg BT 96.88 269.10 Td (the ) Tj ET Q q 0 0 0 rg BT 112.35 269.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 151.15 269.10 Td (of ) Tj ET Q q 0 0 0 rg BT 162.74 269.10 Td (BMS’) Tj ET Q q 0 0 0 rg BT 186.64 269.10 Td (s ) Tj ET Q q 0 0 0 rg BT 193.80 269.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 255.37 269.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 286.95 269.10 Td (located ) Tj ET Q q 0 0 0 rg BT 319.08 269.10 Td (in ) Tj ET Q q 0 0 0 rg BT 330.12 269.10 Td (Mount ) Tj ET Q q 0 0 0 rg BT 359.81 269.10 Td (V) Tj ET Q q 0 0 0 rg BT 365.93 269.10 Td (ernon, ) Tj ET Q q 0 0 0 rg BT 394.46 269.10 Td (Indiana ) Tj ET Q q 0 0 0 rg BT 427.70 269.10 Td (in ) Tj ET Q q 0 0 0 rg BT 438.74 269.10 Td (2015. ) Tj ET Q q 0 0 0 rg BT 464.50 269.10 Td (Substantially ) Tj ET Q q 0 0 0 rg BT 519.99 269.10 Td (all ) Tj ET Q q 0 0 0 rg BT 533.24 269.10 Td (employees ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.10 Td (dedicated ) Tj ET Q q 0 0 0 rg BT 76.81 257.10 Td (to ) Tj ET Q q 0 0 0 rg BT 87.09 257.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.81 257.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 137.07 257.10 Td (business ) Tj ET Q q 0 0 0 rg BT 173.46 257.10 Td (were ) Tj ET Q q 0 0 0 rg BT 195.39 257.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 241.20 257.10 Td (to ) Tj ET Q q 0 0 0 rg BT 250.92 257.10 Td (AstraZeneca.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 58.51 233.10 Td (and ) Tj ET Q q 0 0 0 rg BT 74.03 233.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 125.94 233.10 Td (entered ) Tj ET Q q 0 0 0 rg BT 156.75 233.10 Td (into ) Tj ET Q q 0 0 0 rg BT 173.69 233.10 Td (several ) Tj ET Q q 0 0 0 rg BT 203.39 233.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 250.31 233.10 Td (in ) Tj ET Q q 0 0 0 rg BT 259.48 233.10 Td (connection ) Tj ET Q q 0 0 0 rg BT 304.74 233.10 Td (with ) Tj ET Q q 0 0 0 rg BT 323.90 233.10 Td (the ) Tj ET Q q 0 0 0 rg BT 337.51 233.10 Td (sale, ) Tj ET Q q 0 0 0 rg BT 356.94 233.10 Td (including ) Tj ET Q q 0 0 0 rg BT 396.10 233.10 Td (a ) Tj ET Q q 0 0 0 rg BT 401.92 233.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 429.98 233.10 Td (agreement, ) Tj ET Q q 0 0 0 rg BT 475.51 233.10 Td (a ) Tj ET Q q 0 0 0 rg BT 481.33 233.10 Td (development ) Tj ET Q q 0 0 0 rg BT 534.37 233.10 Td (agreement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.98 221.10 Td (a ) Tj ET Q q 0 0 0 rg BT 61.95 221.10 Td (transitional ) Tj ET Q q 0 0 0 rg BT 110.48 221.10 Td (services ) Tj ET Q q 0 0 0 rg BT 146.22 221.10 Td (agreement. ) Tj ET Q q 0 0 0 rg BT 193.90 221.10 Td (Under ) Tj ET Q q 0 0 0 rg BT 222.43 221.10 Td (those ) Tj ET Q q 0 0 0 rg BT 247.08 221.10 Td (agreements, ) Tj ET Q q 0 0 0 rg BT 298.65 221.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 323.31 221.10 Td (was ) Tj ET Q q 0 0 0 rg BT 342.40 221.10 Td (obligated ) Tj ET Q q 0 0 0 rg BT 383.15 221.10 Td (to ) Tj ET Q q 0 0 0 rg BT 394.46 221.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 424.67 221.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 455.41 221.10 Td (products; ) Tj ET Q q 0 0 0 rg BT 496.16 221.10 Td (to ) Tj ET Q q 0 0 0 rg BT 507.48 221.10 Td (perform ) Tj ET Q q 0 0 0 rg BT 543.22 221.10 Td (ongoing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.10 Td (development ) Tj ET Q q 0 0 0 rg BT 90.72 209.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 129.88 209.10 Td (for ) Tj ET Q q 0 0 0 rg BT 144.61 209.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 174.88 209.10 Td (clinical ) Tj ET Q q 0 0 0 rg BT 207.37 209.10 Td (study ) Tj ET Q q 0 0 0 rg BT 232.11 209.10 Td (programs; ) Tj ET Q q 0 0 0 rg BT 275.72 209.10 Td (and ) Tj ET Q q 0 0 0 rg BT 293.23 209.10 Td (to ) Tj ET Q q 0 0 0 rg BT 304.07 209.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 337.68 209.10 Td (transitional ) Tj ET Q q 0 0 0 rg BT 385.74 209.10 Td (services ) Tj ET Q q 0 0 0 rg BT 421.01 209.10 Td (such ) Tj ET Q q 0 0 0 rg BT 442.41 209.10 Td (as ) Tj ET Q q 0 0 0 rg BT 453.81 209.10 Td (accounting, ) Tj ET Q q 0 0 0 rg BT 503.25 209.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 541.29 209.10 Td (services, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 75.92 197.10 Td (service, ) Tj ET Q q 0 0 0 rg BT 110.01 197.10 Td (distribution, ) Tj ET Q q 0 0 0 rg BT 161.89 197.10 Td (regulatory) Tj ET Q q 0 0 0 rg BT 202.33 197.10 Td (, ) Tj ET Q q 0 0 0 rg BT 208.10 197.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 265.52 197.10 Td (information ) Tj ET Q q 0 0 0 rg BT 316.00 197.10 Td (technology ) Tj ET Q q 0 0 0 rg BT 363.70 197.10 Td (and ) Tj ET Q q 0 0 0 rg BT 381.41 197.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 411.88 197.10 Td (other ) Tj ET Q q 0 0 0 rg BT 435.69 197.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 496.17 197.10 Td (services ) Tj ET Q q 0 0 0 rg BT 531.64 197.10 Td (for ) Tj ET Q q 0 0 0 rg BT 546.57 197.10 Td (various ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 67.94 185.10 Td (in ) Tj ET Q q 0 0 0 rg BT 78.22 185.10 Td (order ) Tj ET Q q 0 0 0 rg BT 101.82 185.10 Td (to ) Tj ET Q q 0 0 0 rg BT 112.09 185.10 Td (facilitate ) Tj ET Q q 0 0 0 rg BT 149.57 185.10 Td (the ) Tj ET Q q 0 0 0 rg BT 164.29 185.10 Td (orderly ) Tj ET Q q 0 0 0 rg BT 195.66 185.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 228.70 185.10 Td (of ) Tj ET Q q 0 0 0 rg BT 239.53 185.10 Td (the ) Tj ET Q q 0 0 0 rg BT 254.25 185.10 Td (business ) Tj ET Q q 0 0 0 rg BT 290.64 185.10 Td (operations.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 161.10 Td (Consideration ) Tj ET Q q 0 0 0 rg BT 94.66 161.10 Td (for ) Tj ET Q q 0 0 0 rg BT 108.89 161.10 Td (the ) Tj ET Q q 0 0 0 rg BT 123.66 161.10 Td (transaction ) Tj ET Q q 0 0 0 rg BT 170.10 161.10 Td (includes ) Tj ET Q q 0 0 0 rg BT 205.98 161.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 212.98 161.10 Td ($2.7 ) Tj ET Q q 0 0 0 rg BT 233.04 161.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.16 161.10 Td ( ) Tj ET Q q 0 0 0 rg BT 261.72 161.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 298.71 161.10 Td (at ) Tj ET Q q 0 0 0 rg BT 308.49 161.10 Td (closing; ) Tj ET Q q 0 0 0 rg BT 342.72 161.10 Td (contingent ) Tj ET Q q 0 0 0 rg BT 387.49 161.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 431.14 161.10 Td (and ) Tj ET Q q 0 0 0 rg BT 448.14 161.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 496.24 161.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 537.68 161.10 Td (payments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.82 149.10 Td (up ) Tj ET Q q 0 0 0 rg BT 59.31 149.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 69.58 149.10 Td ($1.4 ) Tj ET Q q 0 0 0 rg BT 89.58 149.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 115.69 149.10 Td ( ) Tj ET Q q 0 0 0 rg BT 118.18 149.10 Td (\(including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 161.78 149.10 Td ($800 ) Tj ET Q q 0 0 0 rg BT 184.27 149.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.16 149.10 Td ( ) Tj ET Q q 0 0 0 rg BT 215.65 149.10 Td (related ) Tj ET Q q 0 0 0 rg BT 245.34 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 255.61 149.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 293.09 149.10 Td (milestones ) Tj ET Q q 0 0 0 rg BT 338.36 149.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 355.29 149.10 Td ($600 ) Tj ET Q q 0 0 0 rg BT 377.78 149.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.67 149.10 Td ( ) Tj ET Q q 0 0 0 rg BT 409.16 149.10 Td (related ) Tj ET Q q 0 0 0 rg BT 438.86 149.10 Td (to ) Tj ET Q q 0 0 0 rg BT 449.13 149.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 497.15 149.10 Td (milestones, ) Tj ET Q q 0 0 0 rg BT 544.92 149.10 Td (payable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.34 137.10 Td (2020\); ) Tj ET Q q 0 0 0 rg BT 75.00 137.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 105.88 137.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 146.77 137.10 Td (based ) Tj ET Q q 0 0 0 rg BT 172.09 137.10 Td (on ) Tj ET Q q 0 0 0 rg BT 184.65 137.10 Td (net ) Tj ET Q q 0 0 0 rg BT 199.43 137.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 221.42 137.10 Td (through ) Tj ET Q q 0 0 0 rg BT 255.09 137.10 Td (2025 ) Tj ET Q q 0 0 0 rg BT 277.65 137.10 Td (and ) Tj ET Q q 0 0 0 rg BT 294.64 137.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 335.52 137.10 Td (up ) Tj ET Q q 0 0 0 rg BT 348.08 137.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 358.42 137.10 Td ($225 ) Tj ET Q q 0 0 0 rg BT 380.98 137.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.87 137.10 Td ( ) Tj ET Q q 0 0 0 rg BT 412.42 137.10 Td (if ) Tj ET Q q 0 0 0 rg BT 421.09 137.10 Td (and ) Tj ET Q q 0 0 0 rg BT 438.09 137.10 Td (when ) Tj ET Q q 0 0 0 rg BT 462.30 137.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 492.06 137.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 517.95 137.10 Td (are ) Tj ET Q q 0 0 0 rg BT 532.72 137.10 Td (transferred ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 125.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.13 125.10 Td (AstraZeneca. ) Tj ET Q q 0 0 0 rg BT 101.51 125.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 155.05 125.10 Td (will ) Tj ET Q q 0 0 0 rg BT 173.63 125.10 Td (also ) Tj ET Q q 0 0 0 rg BT 192.76 125.10 Td (pay ) Tj ET Q q 0 0 0 rg BT 210.22 125.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 234.37 125.10 Td (for ) Tj ET Q q 0 0 0 rg BT 249.05 125.10 Td (any ) Tj ET Q q 0 0 0 rg BT 266.51 125.10 Td (required ) Tj ET Q q 0 0 0 rg BT 302.84 125.10 Td (product ) Tj ET Q q 0 0 0 rg BT 336.41 125.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 366.10 125.10 Td (at ) Tj ET Q q 0 0 0 rg BT 376.34 125.10 Td (a ) Tj ET Q q 0 0 0 rg BT 383.80 125.10 Td (price ) Tj ET Q q 0 0 0 rg BT 406.81 125.10 Td (approximating ) Tj ET Q q 0 0 0 rg BT 468.15 125.10 Td (the ) Tj ET Q q 0 0 0 rg BT 483.39 125.10 Td (product ) Tj ET Q q 0 0 0 rg BT 516.96 125.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 536.09 125.10 Td (as ) Tj ET Q q 0 0 0 rg BT 547.44 125.10 Td (well ) Tj ET Q q 0 0 0 rg BT 567.68 125.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.10 Td (negotiated ) Tj ET Q q 0 0 0 rg BT 80.15 113.10 Td (transitional ) Tj ET Q q 0 0 0 rg BT 127.64 113.10 Td (service ) Tj ET Q q 0 0 0 rg BT 158.46 113.10 Td (fees.) Tj ET Q endstream endobj 143 0 obj <> endobj 144 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Royalty ) Tj ET Q q 0 0 0 rg BT 70.17 749.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 91.54 749.10 Td (on ) Tj ET Q q 0 0 0 rg BT 104.04 749.10 Td (net ) Tj ET Q q 0 0 0 rg BT 118.76 749.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 140.70 749.10 Td (are ) Tj ET Q q 0 0 0 rg BT 155.40 749.10 Td (as ) Tj ET Q q 0 0 0 rg BT 166.23 749.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 719.60 337.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 372.50 719.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 397.50 719.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 719.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 719.60 26.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 719.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 719.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 719.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 545.50 719.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 550.50 719.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 693.60 337.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 372.50 693.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 397.50 693.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 422.50 693.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 446.50 693.60 26.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 472.50 693.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 693.60 25.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 521.50 693.60 24.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 545.50 693.60 5.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 550.50 693.60 25.00 -13.00 re f /GS0 gs BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 376.5 722.580078125 m 392.5 722.580078125 l s q 0 0 0 rg BT 376.50 723.83 Td (2015) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 401.5 722.580078125 m 417.5 722.580078125 l s q 0 0 0 rg BT 401.50 723.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 426 722.580078125 m 442 722.580078125 l s q 0 0 0 rg BT 426.00 723.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 451 722.580078125 m 467 722.580078125 l s q 0 0 0 rg BT 451.00 723.83 Td (2018) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 476 722.580078125 m 492 722.580078125 l s q 0 0 0 rg BT 476.00 723.83 Td (2019) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 500.5 722.580078125 m 516.5 722.580078125 l s q 0 0 0 rg BT 500.50 723.83 Td (2020) Tj ET Q BT /F2 8.00 Tf ET 0 0 0 RG /GS0 gs 0.76 w 0 i [] 0 d 1 J 1 j 3 M 528.65 722.580078125 m 567.3140625 722.580078125 l s q 0 0 0 rg BT 528.65 723.83 Td (2021 - 2025) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 38.00 710.85 Td (Onglyza* ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 74.75 710.85 Td (and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 89.99 710.85 Td (Farxiga*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 123.49 710.85 Td ( ) Tj ET Q q 0 0 0 rg BT 125.57 710.85 Td (W) Tj ET Q q 0 0 0 rg BT 133.35 710.85 Td (orldwide Net Sales up to $500 million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.65 710.17 Td (35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.65 710.17 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.65 710.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.65 710.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 463.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 710.17 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 710.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 526.65 710.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 536.65 710.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 710.17 Td (-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 710.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 710.17 Td (%) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 38.00 697.85 Td (Onglyza*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 72.50 697.85 Td ( and ) Tj ET Q BT /F3 9.00 Tf ET q 0 0 0 rg BT 89.99 697.85 Td (Farxiga*) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 123.49 697.85 Td ( ) Tj ET Q q 0 0 0 rg BT 125.57 697.85 Td (W) Tj ET Q q 0 0 0 rg BT 133.35 697.85 Td (orldwide Net Sales over $500 million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.65 697.17 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 697.17 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.65 697.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.65 697.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 463.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 697.17 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 697.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 526.65 697.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 536.65 697.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 697.17 Td (-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 697.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 697.17 Td (%) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 38.00 684.86 Td (Amylin products U.S. Net Sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.65 684.17 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 684.17 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.65 684.17 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.65 684.17 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 463.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 684.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 684.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 531.65 684.17 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 536.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.30 684.17 Td (-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 684.17 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 684.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 657.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.24 657.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 76.04 657.10 Td (and ) Tj ET Q q 0 0 0 rg BT 92.17 657.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 113.30 657.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 150.52 657.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 193.86 657.10 Td (contained ) Tj ET Q q 0 0 0 rg BT 234.42 657.10 Td (multiple ) Tj ET Q q 0 0 0 rg BT 269.44 657.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 306.67 657.10 Td (to ) Tj ET Q q 0 0 0 rg BT 316.14 657.10 Td (be ) Tj ET Q q 0 0 0 rg BT 327.27 657.10 Td (delivered ) Tj ET Q q 0 0 0 rg BT 366.16 657.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 412.29 657.10 Td (to ) Tj ET Q q 0 0 0 rg BT 421.76 657.10 Td (the ) Tj ET Q q 0 0 0 rg BT 435.67 657.10 Td (closing ) Tj ET Q q 0 0 0 rg BT 466.25 657.10 Td (of ) Tj ET Q q 0 0 0 rg BT 476.27 657.10 Td (the ) Tj ET Q q 0 0 0 rg BT 490.18 657.10 Td (transaction, ) Tj ET Q q 0 0 0 rg BT 538.24 657.10 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 645.10 Td (the ) Tj ET Q q 0 0 0 rg BT 49.73 645.10 Td (China ) Tj ET Q q 0 0 0 rg BT 75.13 645.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 109.41 645.10 Td (business ) Tj ET Q q 0 0 0 rg BT 144.81 645.10 Td (\(transferred ) Tj ET Q q 0 0 0 rg BT 192.96 645.10 Td (in ) Tj ET Q q 0 0 0 rg BT 202.25 645.10 Td (2014\), ) Tj ET Q q 0 0 0 rg BT 229.59 645.10 Td (the ) Tj ET Q q 0 0 0 rg BT 243.32 645.10 Td (Mount ) Tj ET Q q 0 0 0 rg BT 271.39 645.10 Td (V) Tj ET Q q 0 0 0 rg BT 277.51 645.10 Td (ernon, ) Tj ET Q q 0 0 0 rg BT 304.29 645.10 Td (Indiana ) Tj ET Q q 0 0 0 rg BT 335.79 645.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 395.61 645.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 425.44 645.10 Td (\(transferred ) Tj ET Q q 0 0 0 rg BT 473.59 645.10 Td (in ) Tj ET Q q 0 0 0 rg BT 482.88 645.10 Td (2015\), ) Tj ET Q q 0 0 0 rg BT 510.23 645.10 Td (and ) Tj ET Q q 0 0 0 rg BT 526.18 645.10 Td (the ) Tj ET Q q 0 0 0 rg BT 539.91 645.10 Td (activities ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 633.10 Td (under ) Tj ET Q q 0 0 0 rg BT 61.06 633.10 Td (the ) Tj ET Q q 0 0 0 rg BT 75.58 633.10 Td (development ) Tj ET Q q 0 0 0 rg BT 129.52 633.10 Td (and ) Tj ET Q q 0 0 0 rg BT 146.25 633.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 175.22 633.10 Td (agreements. ) Tj ET Q q 0 0 0 rg BT 225.55 633.10 Td (Each ) Tj ET Q q 0 0 0 rg BT 247.83 633.10 Td (of ) Tj ET Q q 0 0 0 rg BT 258.45 633.10 Td (these ) Tj ET Q q 0 0 0 rg BT 281.29 633.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 319.13 633.10 Td (was ) Tj ET Q q 0 0 0 rg BT 336.98 633.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 384.25 633.10 Td (to ) Tj ET Q q 0 0 0 rg BT 394.33 633.10 Td (have ) Tj ET Q q 0 0 0 rg BT 415.50 633.10 Td (a ) Tj ET Q q 0 0 0 rg BT 422.23 633.10 Td (standalone ) Tj ET Q q 0 0 0 rg BT 467.29 633.10 Td (value. ) Tj ET Q q 0 0 0 rg BT 493.23 633.10 Td (As ) Tj ET Q q 0 0 0 rg BT 506.64 633.10 Td (a ) Tj ET Q q 0 0 0 rg BT 513.37 633.10 Td (result, ) Tj ET Q q 0 0 0 rg BT 540.39 633.10 Td (a ) Tj ET Q q 0 0 0 rg BT 547.12 633.10 Td (portion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 621.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.12 621.10 Td (the ) Tj ET Q q 0 0 0 rg BT 60.14 621.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 115.80 621.10 Td (received ) Tj ET Q q 0 0 0 rg BT 151.46 621.10 Td (at ) Tj ET Q q 0 0 0 rg BT 160.47 621.10 Td (closing ) Tj ET Q q 0 0 0 rg BT 191.15 621.10 Td (was ) Tj ET Q q 0 0 0 rg BT 208.50 621.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 246.38 621.10 Td (to ) Tj ET Q q 0 0 0 rg BT 255.95 621.10 Td (the ) Tj ET Q q 0 0 0 rg BT 269.96 621.10 Td (undelivered ) Tj ET Q q 0 0 0 rg BT 318.96 621.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 356.30 621.10 Td (using ) Tj ET Q q 0 0 0 rg BT 379.76 621.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.77 621.10 Td (relative ) Tj ET Q q 0 0 0 rg BT 425.55 621.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 454.01 621.10 Td (price ) Tj ET Q q 0 0 0 rg BT 475.79 621.10 Td (method ) Tj ET Q q 0 0 0 rg BT 507.58 621.10 Td (after ) Tj ET Q q 0 0 0 rg BT 527.69 621.10 Td (determining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.58 609.10 Td (best ) Tj ET Q q 0 0 0 rg BT 69.04 609.10 Td (estimated ) Tj ET Q q 0 0 0 rg BT 109.72 609.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 138.74 609.10 Td (price ) Tj ET Q q 0 0 0 rg BT 161.09 609.10 Td (for ) Tj ET Q q 0 0 0 rg BT 175.11 609.10 Td (each ) Tj ET Q q 0 0 0 rg BT 195.78 609.10 Td (element. ) Tj ET Q q 0 0 0 rg BT 232.12 609.10 Td (The ) Tj ET Q q 0 0 0 rg BT 250.02 609.10 Td (remaining ) Tj ET Q q 0 0 0 rg BT 292.92 609.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 325.28 609.10 Td (of ) Tj ET Q q 0 0 0 rg BT 335.97 609.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 392.20 609.10 Td (was ) Tj ET Q q 0 0 0 rg BT 410.11 609.10 Td (included ) Tj ET Q q 0 0 0 rg BT 446.90 609.10 Td (in ) Tj ET Q q 0 0 0 rg BT 457.04 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 471.61 609.10 Td (calculation ) Tj ET Q q 0 0 0 rg BT 517.84 609.10 Td (for ) Tj ET Q q 0 0 0 rg BT 531.85 609.10 Td (the ) Tj ET Q q 0 0 0 rg BT 546.43 609.10 Td (gain ) Tj ET Q q 0 0 0 rg BT 566.01 609.10 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 597.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 54.19 597.10 Td (of ) Tj ET Q q 0 0 0 rg BT 65.17 597.10 Td (the ) Tj ET Q q 0 0 0 rg BT 80.03 597.10 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 115.44 597.10 Td (business. ) Tj ET Q q 0 0 0 rg BT 154.48 597.10 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 201.57 597.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 243.10 597.10 Td (and ) Tj ET Q q 0 0 0 rg BT 260.18 597.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 291.16 597.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 332.13 597.10 Td (are ) Tj ET Q q 0 0 0 rg BT 346.98 597.10 Td (similarly ) Tj ET Q q 0 0 0 rg BT 385.18 597.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 423.92 597.10 Td (among ) Tj ET Q q 0 0 0 rg BT 453.78 597.10 Td (the ) Tj ET Q q 0 0 0 rg BT 468.64 597.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 514.61 597.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 552.80 597.10 Td (if ) Tj ET Q q 0 0 0 rg BT 561.56 597.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 585.10 Td (when ) Tj ET Q q 0 0 0 rg BT 60.49 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 75.53 585.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 112.25 585.10 Td (are ) Tj ET Q q 0 0 0 rg BT 127.29 585.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 175.09 585.10 Td (to ) Tj ET Q q 0 0 0 rg BT 185.70 585.10 Td (be ) Tj ET Q q 0 0 0 rg BT 197.97 585.10 Td (payable ) Tj ET Q q 0 0 0 rg BT 231.89 585.10 Td (to ) Tj ET Q q 0 0 0 rg BT 242.50 585.10 Td (BMS. ) Tj ET Q q 0 0 0 rg BT 268.32 585.10 Td (Amounts ) Tj ET Q q 0 0 0 rg BT 307.82 585.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 346.74 585.10 Td (to ) Tj ET Q q 0 0 0 rg BT 357.35 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 372.39 585.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 390.77 585.10 Td (of ) Tj ET Q q 0 0 0 rg BT 401.93 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 416.97 585.10 Td (business ) Tj ET Q q 0 0 0 rg BT 453.69 585.10 Td (are ) Tj ET Q q 0 0 0 rg BT 468.73 585.10 Td (immediately ) Tj ET Q q 0 0 0 rg BT 521.54 585.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 568.23 585.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.47 573.10 Td (results ) Tj ET Q q 0 0 0 rg BT 80.84 573.10 Td (of ) Tj ET Q q 0 0 0 rg BT 92.43 573.10 Td (operations. ) Tj ET Q q 0 0 0 rg BT 139.12 573.10 Td (Amounts ) Tj ET Q q 0 0 0 rg BT 179.05 573.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 218.39 573.10 Td (to ) Tj ET Q q 0 0 0 rg BT 229.43 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 244.90 573.10 Td (other ) Tj ET Q q 0 0 0 rg BT 268.70 573.10 Td (elements ) Tj ET Q q 0 0 0 rg BT 307.50 573.10 Td (are ) Tj ET Q q 0 0 0 rg BT 322.97 573.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 370.09 573.10 Td (in ) Tj ET Q q 0 0 0 rg BT 381.12 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 396.59 573.10 Td (results ) Tj ET Q q 0 0 0 rg BT 425.96 573.10 Td (of ) Tj ET Q q 0 0 0 rg BT 437.55 573.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 482.46 573.10 Td (only ) Tj ET Q q 0 0 0 rg BT 503.49 573.10 Td (to ) Tj ET Q q 0 0 0 rg BT 514.53 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 530.00 573.10 Td (extent ) Tj ET Q q 0 0 0 rg BT 557.69 573.10 Td (each ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 561.10 Td (element ) Tj ET Q q 0 0 0 rg BT 70.15 561.10 Td (has ) Tj ET Q q 0 0 0 rg BT 85.98 561.10 Td (been ) Tj ET Q q 0 0 0 rg BT 107.36 561.10 Td (delivered.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 537.10 Td (Consideration ) Tj ET Q q 0 0 0 rg BT 95.18 537.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 106.59 537.10 Td ($179 ) Tj ET Q q 0 0 0 rg BT 129.66 537.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 158.55 537.10 Td ( ) Tj ET Q q 0 0 0 rg BT 161.63 537.10 Td (was ) Tj ET Q q 0 0 0 rg BT 180.26 537.10 Td (received ) Tj ET Q q 0 0 0 rg BT 217.20 537.10 Td (in ) Tj ET Q q 0 0 0 rg BT 228.05 537.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 251.13 537.10 Td (for ) Tj ET Q q 0 0 0 rg BT 265.86 537.10 Td (the ) Tj ET Q q 0 0 0 rg BT 281.16 537.10 Td (transfer ) Tj ET Q q 0 0 0 rg BT 314.77 537.10 Td (of ) Tj ET Q q 0 0 0 rg BT 326.18 537.10 Td (the ) Tj ET Q q 0 0 0 rg BT 341.47 537.10 Td (Mount ) Tj ET Q q 0 0 0 rg BT 370.99 537.10 Td (V) Tj ET Q q 0 0 0 rg BT 377.11 537.10 Td (ernon, ) Tj ET Q q 0 0 0 rg BT 405.45 537.10 Td (Indiana ) Tj ET Q q 0 0 0 rg BT 438.51 537.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 499.90 537.10 Td (facility ) Tj ET Q q 0 0 0 rg BT 531.30 537.10 Td (and ) Tj ET Q q 0 0 0 rg BT 548.81 537.10 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 525.10 Td (inventories ) Tj ET Q q 0 0 0 rg BT 82.15 525.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 118.86 525.10 Td (in ) Tj ET Q q 0 0 0 rg BT 128.35 525.10 Td (a ) Tj ET Q q 0 0 0 rg BT 134.51 525.10 Td (gain ) Tj ET Q q 0 0 0 rg BT 153.44 525.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 163.48 525.10 Td ($79 ) Tj ET Q q 0 0 0 rg BT 180.20 525.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 209.09 525.10 Td ( ) Tj ET Q q 0 0 0 rg BT 210.81 525.10 Td (for ) Tj ET Q q 0 0 0 rg BT 224.18 525.10 Td (the ) Tj ET Q q 0 0 0 rg BT 238.11 525.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 273.72 525.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 311.52 525.10 Td (to ) Tj ET Q q 0 0 0 rg BT 321.01 525.10 Td (the ) Tj ET Q q 0 0 0 rg BT 334.95 525.10 Td (delivered ) Tj ET Q q 0 0 0 rg BT 373.86 525.10 Td (elements. ) Tj ET Q q 0 0 0 rg BT 413.62 525.10 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 459.78 525.10 Td (consideration ) Tj ET Q q 0 0 0 rg BT 515.37 525.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.41 525.10 Td ($100 ) Tj ET Q q 0 0 0 rg BT 547.13 525.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 513.10 Td (was ) Tj ET Q q 0 0 0 rg BT 54.05 513.10 Td (received ) Tj ET Q q 0 0 0 rg BT 90.41 513.10 Td (in ) Tj ET Q q 0 0 0 rg BT 100.69 513.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 123.19 513.10 Td (from ) Tj ET Q q 0 0 0 rg BT 144.58 513.10 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 197.60 513.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 220.10 513.10 Td (achievement ) Tj ET Q q 0 0 0 rg BT 273.13 513.10 Td (of ) Tj ET Q q 0 0 0 rg BT 283.96 513.10 Td (a ) Tj ET Q q 0 0 0 rg BT 290.90 513.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 334.49 513.10 Td (approval ) Tj ET Q q 0 0 0 rg BT 371.98 513.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 413.36 513.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 450.85 513.10 Td (in ) Tj ET Q q 0 0 0 rg BT 461.13 513.10 Td (an ) Tj ET Q q 0 0 0 rg BT 473.07 513.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 515.56 513.10 Td (gain.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 489.10 Td (Consideration ) Tj ET Q q 0 0 0 rg BT 94.70 489.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 133.39 489.10 Td (to ) Tj ET Q q 0 0 0 rg BT 143.77 489.10 Td (the ) Tj ET Q q 0 0 0 rg BT 158.58 489.10 Td (development ) Tj ET Q q 0 0 0 rg BT 212.83 489.10 Td (and ) Tj ET Q q 0 0 0 rg BT 229.87 489.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 259.14 489.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 307.27 489.10 Td (was ) Tj ET Q q 0 0 0 rg BT 325.42 489.10 Td (amortized ) Tj ET Q q 0 0 0 rg BT 368.00 489.10 Td (over ) Tj ET Q q 0 0 0 rg BT 388.37 489.10 Td (the ) Tj ET Q q 0 0 0 rg BT 403.19 489.10 Td (applicable ) Tj ET Q q 0 0 0 rg BT 446.87 489.10 Td (service ) Tj ET Q q 0 0 0 rg BT 477.79 489.10 Td (periods. ) Tj ET Q q 0 0 0 rg BT 511.75 489.10 Td (Amortization ) Tj ET Q q 0 0 0 rg BT 567.67 489.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 477.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 71.48 477.10 Td (income ) Tj ET Q q 0 0 0 rg BT 103.10 477.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 143.60 477.10 Td (to ) Tj ET Q q 0 0 0 rg BT 153.55 477.10 Td (the ) Tj ET Q q 0 0 0 rg BT 167.95 477.10 Td (development ) Tj ET Q q 0 0 0 rg BT 221.78 477.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 265.60 477.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 291.66 477.10 Td (in ) Tj ET Q q 0 0 0 rg BT 301.61 477.10 Td (December ) Tj ET Q q 0 0 0 rg BT 344.88 477.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 367.06 477.10 Td (and ) Tj ET Q q 0 0 0 rg BT 383.67 477.10 Td (was ) Tj ET Q q 0 0 0 rg BT 401.40 477.10 Td (included ) Tj ET Q q 0 0 0 rg BT 438.02 477.10 Td (in ) Tj ET Q q 0 0 0 rg BT 447.98 477.10 Td (other ) Tj ET Q q 0 0 0 rg BT 470.70 477.10 Td (income ) Tj ET Q q 0 0 0 rg BT 502.31 477.10 Td (as ) Tj ET Q q 0 0 0 rg BT 512.82 477.10 Td (the ) Tj ET Q q 0 0 0 rg BT 527.22 477.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 544.95 477.10 Td (of ) Tj ET Q q 0 0 0 rg BT 555.45 477.10 Td (these ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 465.10 Td (services ) Tj ET Q q 0 0 0 rg BT 70.30 465.10 Td (was ) Tj ET Q q 0 0 0 rg BT 87.95 465.10 Td (not ) Tj ET Q q 0 0 0 rg BT 102.82 465.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 148.23 465.10 Td (part ) Tj ET Q q 0 0 0 rg BT 165.87 465.10 Td (of ) Tj ET Q q 0 0 0 rg BT 176.29 465.10 Td (BMS’) Tj ET Q q 0 0 0 rg BT 200.19 465.10 Td (s ) Tj ET Q q 0 0 0 rg BT 206.18 465.10 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 241.05 465.10 Td (major ) Tj ET Q q 0 0 0 rg BT 266.47 465.10 Td (or ) Tj ET Q q 0 0 0 rg BT 276.89 465.10 Td (central ) Tj ET Q q 0 0 0 rg BT 306.19 465.10 Td (operations. ) Tj ET Q q 0 0 0 rg BT 351.98 465.10 Td (Amortization ) Tj ET Q q 0 0 0 rg BT 407.39 465.10 Td (of ) Tj ET Q q 0 0 0 rg BT 417.81 465.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 453.21 465.10 Td (income ) Tj ET Q q 0 0 0 rg BT 484.74 465.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 525.15 465.10 Td (to ) Tj ET Q q 0 0 0 rg BT 535.03 465.10 Td (the ) Tj ET Q q 0 0 0 rg BT 549.34 465.10 Td (supply ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 80.11 453.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 106.45 453.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.69 453.10 Td (December ) Tj ET Q q 0 0 0 rg BT 160.24 453.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 182.71 453.10 Td (and ) Tj ET Q q 0 0 0 rg BT 199.61 453.10 Td (was ) Tj ET Q q 0 0 0 rg BT 217.63 453.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 255.07 453.10 Td (in ) Tj ET Q q 0 0 0 rg BT 265.32 453.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 298.87 453.10 Td (revenues. ) Tj ET Q q 0 0 0 rg BT 339.37 453.10 Td (Revenues ) Tj ET Q q 0 0 0 rg BT 380.72 453.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 421.50 453.10 Td (to ) Tj ET Q q 0 0 0 rg BT 431.75 453.10 Td (the ) Tj ET Q q 0 0 0 rg BT 446.43 453.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 475.57 453.10 Td (agreement ) Tj ET Q q 0 0 0 rg BT 519.67 453.10 Td (were ) Tj ET Q q 0 0 0 rg BT 541.57 453.10 Td (included ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 441.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 79.87 441.10 Td (revenues.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 417.10 Td (Consideration ) Tj ET Q q 0 0 0 rg BT 93.68 417.10 Td (for ) Tj ET Q q 0 0 0 rg BT 106.92 417.10 Td (the ) Tj ET Q q 0 0 0 rg BT 120.72 417.10 Td (transaction ) Tj ET Q q 0 0 0 rg BT 166.17 417.10 Td (is ) Tj ET Q q 0 0 0 rg BT 174.42 417.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 214.31 417.10 Td (for ) Tj ET Q q 0 0 0 rg BT 227.55 417.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 246.90 417.10 Td (flow ) Tj ET Q q 0 0 0 rg BT 266.80 417.10 Td (purposes ) Tj ET Q q 0 0 0 rg BT 303.93 417.10 Td (based ) Tj ET Q q 0 0 0 rg BT 328.28 417.10 Td (on ) Tj ET Q q 0 0 0 rg BT 339.86 417.10 Td (the ) Tj ET Q q 0 0 0 rg BT 353.66 417.10 Td (allocation ) Tj ET Q q 0 0 0 rg BT 394.66 417.10 Td (process ) Tj ET Q q 0 0 0 rg BT 426.23 417.10 Td (described ) Tj ET Q q 0 0 0 rg BT 466.13 417.10 Td (above, ) Tj ET Q q 0 0 0 rg BT 494.08 417.10 Td (either ) Tj ET Q q 0 0 0 rg BT 518.42 417.10 Td (as ) Tj ET Q q 0 0 0 rg BT 528.33 417.10 Td (an ) Tj ET Q q 0 0 0 rg BT 539.35 417.10 Td (investing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.10 Td (activity ) Tj ET Q q 0 0 0 rg BT 68.26 405.10 Td (if ) Tj ET Q q 0 0 0 rg BT 76.63 405.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 117.22 405.10 Td (to ) Tj ET Q q 0 0 0 rg BT 127.26 405.10 Td (the ) Tj ET Q q 0 0 0 rg BT 141.74 405.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 159.55 405.10 Td (of ) Tj ET Q q 0 0 0 rg BT 170.15 405.10 Td (the ) Tj ET Q q 0 0 0 rg BT 184.63 405.10 Td (business ) Tj ET Q q 0 0 0 rg BT 220.79 405.10 Td (or ) Tj ET Q q 0 0 0 rg BT 231.39 405.10 Td (related ) Tj ET Q q 0 0 0 rg BT 260.85 405.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 286.45 405.10 Td (or ) Tj ET Q q 0 0 0 rg BT 297.04 405.10 Td (as ) Tj ET Q q 0 0 0 rg BT 307.64 405.10 Td (an ) Tj ET Q q 0 0 0 rg BT 319.34 405.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 359.37 405.10 Td (activity ) Tj ET Q q 0 0 0 rg BT 391.63 405.10 Td (if ) Tj ET Q q 0 0 0 rg BT 400.00 405.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 440.59 405.10 Td (to ) Tj ET Q q 0 0 0 rg BT 450.63 405.10 Td (the ) Tj ET Q q 0 0 0 rg BT 465.12 405.10 Td (transitional ) Tj ET Q q 0 0 0 rg BT 512.37 405.10 Td (services, ) Tj ET Q q 0 0 0 rg BT 549.34 405.10 Td (supply ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 393.10 Td (arrangement ) Tj ET Q q 0 0 0 rg BT 88.47 393.10 Td (or ) Tj ET Q q 0 0 0 rg BT 99.30 393.10 Td (development ) Tj ET Q q 0 0 0 rg BT 153.45 393.10 Td (agreement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.43 369.10 Td (September ) Tj ET Q q 0 0 0 rg BT 93.30 369.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 118.90 369.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 143.13 369.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 189.53 369.10 Td (a ) Tj ET Q q 0 0 0 rg BT 197.07 369.10 Td (percentage ) Tj ET Q q 0 0 0 rg BT 243.48 369.10 Td (of ) Tj ET Q q 0 0 0 rg BT 254.91 369.10 Td (its ) Tj ET Q q 0 0 0 rg BT 267.46 369.10 Td (future ) Tj ET Q q 0 0 0 rg BT 294.44 369.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 325.86 369.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 351.75 369.10 Td (on ) Tj ET Q q 0 0 0 rg BT 364.16 369.10 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 397.82 369.10 Td (net ) Tj ET Q q 0 0 0 rg BT 413.14 369.10 Td (product ) Tj ET Q q 0 0 0 rg BT 446.79 369.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 469.33 369.10 Td (in ) Tj ET Q q 0 0 0 rg BT 480.21 369.10 Td (the ) Tj ET Q q 0 0 0 rg BT 495.53 369.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 516.41 369.10 Td (to ) Tj ET Q q 0 0 0 rg BT 527.29 369.10 Td (CPPIB. ) Tj ET Q q 0 0 0 rg BT 560.46 369.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 82.60 357.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 108.68 357.10 Td (represent ) Tj ET Q q 0 0 0 rg BT 148.62 357.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 209.68 357.10 Td (70%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 228.01 357.10 Td ( ) Tj ET Q q 0 0 0 rg BT 231.31 357.10 Td (of ) Tj ET Q q 0 0 0 rg BT 242.94 357.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 281.23 357.10 Td (future ) Tj ET Q q 0 0 0 rg BT 308.40 357.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 346.13 357.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 370.56 357.10 Td (is ) Tj ET Q q 0 0 0 rg BT 380.52 357.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 413.81 357.10 Td (to ) Tj ET Q q 0 0 0 rg BT 424.89 357.10 Td (in ) Tj ET Q q 0 0 0 rg BT 435.97 357.10 Td (2019 ) Tj ET Q q 0 0 0 rg BT 459.26 357.10 Td (to ) Tj ET Q q 0 0 0 rg BT 470.34 357.10 Td (2025. ) Tj ET Q q 0 0 0 rg BT 496.14 357.10 Td (In ) Tj ET Q q 0 0 0 rg BT 507.77 357.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 548.82 357.10 Td (for ) Tj ET Q q 0 0 0 rg BT 563.78 357.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.10 Td (transfer) Tj ET Q q 0 0 0 rg BT 66.14 345.10 Td (, ) Tj ET Q q 0 0 0 rg BT 70.85 345.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.19 345.10 Td (will ) Tj ET Q q 0 0 0 rg BT 111.97 345.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 143.05 345.10 Td (an ) Tj ET Q q 0 0 0 rg BT 154.70 345.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 196.91 345.10 Td (tiered-based ) Tj ET Q q 0 0 0 rg BT 247.99 345.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 278.53 345.10 Td (on ) Tj ET Q q 0 0 0 rg BT 290.26 345.10 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 323.03 345.10 Td (net ) Tj ET Q q 0 0 0 rg BT 337.46 345.10 Td (product ) Tj ET Q q 0 0 0 rg BT 370.23 345.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 391.88 345.10 Td (in ) Tj ET Q q 0 0 0 rg BT 401.88 345.10 Td (the ) Tj ET Q q 0 0 0 rg BT 416.31 345.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 436.31 345.10 Td (from ) Tj ET Q q 0 0 0 rg BT 457.97 345.10 Td (CPPIB ) Tj ET Q q 0 0 0 rg BT 487.98 345.10 Td (in ) Tj ET Q q 0 0 0 rg BT 497.97 345.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 520.19 345.10 Td (through ) Tj ET Q q 0 0 0 rg BT 553.51 345.10 Td (2018. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.10 Td (These ) Tj ET Q q 0 0 0 rg BT 62.38 333.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 99.31 333.10 Td (are ) Tj ET Q q 0 0 0 rg BT 114.02 333.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 154.83 333.10 Td (in ) Tj ET Q q 0 0 0 rg BT 165.11 333.10 Td (other ) Tj ET Q q 0 0 0 rg BT 188.16 333.10 Td (income ) Tj ET Q q 0 0 0 rg BT 220.09 333.10 Td (and ) Tj ET Q q 0 0 0 rg BT 237.03 333.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 258.96 333.10 Td ($97 ) Tj ET Q q 0 0 0 rg BT 276.46 333.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.35 333.10 Td ( ) Tj ET Q q 0 0 0 rg BT 307.85 333.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.13 333.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 338.13 333.10 Td ( ) Tj ET Q q 0 0 0 rg BT 340.63 333.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.57 333.10 Td ($134 ) Tj ET Q q 0 0 0 rg BT 380.07 333.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.96 333.10 Td ( ) Tj ET Q q 0 0 0 rg BT 411.46 333.10 Td (in ) Tj ET Q q 0 0 0 rg BT 421.74 333.10 Td (2016. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.10 Td (In ) Tj ET Q q 0 0 0 rg BT 46.62 309.10 Td (November ) Tj ET Q q 0 0 0 rg BT 91.12 309.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 115.91 309.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 139.33 309.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 184.93 309.10 Td (a ) Tj ET Q q 0 0 0 rg BT 191.66 309.10 Td (percentage ) Tj ET Q q 0 0 0 rg BT 237.25 309.10 Td (of ) Tj ET Q q 0 0 0 rg BT 247.88 309.10 Td (its ) Tj ET Q q 0 0 0 rg BT 259.62 309.10 Td (future ) Tj ET Q q 0 0 0 rg BT 285.79 309.10 Td (royalty ) Tj ET Q q 0 0 0 rg BT 316.40 309.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 341.47 309.10 Td (on ) Tj ET Q q 0 0 0 rg BT 353.77 309.10 Td (a ) Tj ET Q q 0 0 0 rg BT 360.50 309.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 391.68 309.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 402.30 309.10 Td (Onglyza*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 440.63 309.10 Td ( ) Tj ET Q q 0 0 0 rg BT 442.92 309.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 459.65 309.10 Td (Farxiga*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.87 309.10 Td ( ) Tj ET Q q 0 0 0 rg BT 499.16 309.10 Td (net ) Tj ET Q q 0 0 0 rg BT 513.67 309.10 Td (product ) Tj ET Q q 0 0 0 rg BT 546.51 309.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 568.24 309.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.10 Td (Royalty ) Tj ET Q q 0 0 0 rg BT 70.56 297.10 Td (Pharma. ) Tj ET Q q 0 0 0 rg BT 106.30 297.10 Td (The ) Tj ET Q q 0 0 0 rg BT 124.74 297.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 170.95 297.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 196.62 297.10 Td (represent ) Tj ET Q q 0 0 0 rg BT 236.17 297.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.82 297.10 Td (20%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.15 297.10 Td ( ) Tj ET Q q 0 0 0 rg BT 318.05 297.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.73 297.10 Td (25%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.06 297.10 Td ( ) Tj ET Q q 0 0 0 rg BT 349.96 297.10 Td (of ) Tj ET Q q 0 0 0 rg BT 361.18 297.10 Td (potential ) Tj ET Q q 0 0 0 rg BT 399.07 297.10 Td (future ) Tj ET Q q 0 0 0 rg BT 425.85 297.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 463.18 297.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 487.20 297.10 Td (is ) Tj ET Q q 0 0 0 rg BT 496.77 297.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 529.66 297.10 Td (to ) Tj ET Q q 0 0 0 rg BT 540.33 297.10 Td (for ) Tj ET Q q 0 0 0 rg BT 554.89 297.10 Td (those ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.10 Td (products ) Tj ET Q q 0 0 0 rg BT 73.08 285.10 Td 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Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 538.78 285.10 Td (Farxiga*) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.10 Td (net ) Tj ET Q q 0 0 0 rg BT 50.72 273.10 Td (product ) Tj ET Q q 0 0 0 rg BT 83.76 273.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 105.70 273.10 Td (from ) Tj ET Q q 0 0 0 rg BT 127.64 273.10 Td (Royalty ) Tj ET Q q 0 0 0 rg BT 161.81 273.10 Td (Pharma ) Tj ET Q q 0 0 0 rg BT 194.85 273.10 Td (in ) Tj ET Q q 0 0 0 rg BT 205.13 273.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 227.63 273.10 Td (and ) Tj ET Q q 0 0 0 rg BT 244.57 273.10 Td (2019, ) Tj ET Q q 0 0 0 rg BT 269.57 273.10 Td (which ) Tj ET Q q 0 0 0 rg BT 296.51 273.10 Td (will ) Tj ET Q q 0 0 0 rg BT 314.56 273.10 Td (be ) Tj ET Q q 0 0 0 rg BT 326.50 273.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 367.32 273.10 Td (in ) Tj ET Q q 0 0 0 rg BT 377.60 273.10 Td (other ) Tj ET Q q 0 0 0 rg BT 400.64 273.10 Td (income ) Tj ET Q q 0 0 0 rg BT 432.58 273.10 Td (when ) Tj ET Q q 0 0 0 rg BT 456.74 273.10 Td (earned.) 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10.00 Tf ET q 0 0 0 rg BT 57.00 532.17 Td (Divestiture and other proceeds) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 532.17 Td (302) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 532.17 Td (216) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 532.17 Td (374) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 492.60 412.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 492.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 492.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 492.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 492.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 505.6 m 512.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 505.6 m 516.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 505.6 m 576.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 505.6 m 512.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 492.6 m 512.5 492.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 505.6 m 516.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 505.6 m 576.5 505.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 492.6 m 576.5 492.6 l s BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 509.33 Td (Selected ) Tj ET Q q 0 0 0 rg BT 75.93 509.33 Td (Alliance Balance Sheet Information:) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 490.75 509.83 Td (December) Tj ET Q q 0 0 0 rg BT 525.32 509.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 496.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 496.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 496.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 483.17 Td (Deferred income – Services not yet performed for ) Tj ET Q q 0 0 0 rg BT 240.59 483.17 Td (AstraZeneca) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 483.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 483.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 483.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 483.17 Td (38) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 454.53505859375 m 63.2314453125 454.53505859375 l s q 0 0 0 rg BT 36.00 456.10 Td (Sanofi) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 432.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.19 432.10 Td (and ) Tj ET Q q 0 0 0 rg BT 77.70 432.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 106.88 432.10 Td (have ) Tj ET Q q 0 0 0 rg BT 128.83 432.10 Td (co-development ) Tj ET Q q 0 0 0 rg BT 196.32 432.10 Td (and ) Tj ET Q q 0 0 0 rg BT 213.83 432.10 Td (co-commercialization ) Tj ET Q q 0 0 0 rg BT 304.07 432.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 352.68 432.10 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 367.41 432.10 Td (Plavix* ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.02 432.10 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 418.53 432.10 Td (A) Tj ET Q q 0 0 0 rg BT 424.08 432.10 Td (vapr) Tj ET Q q 0 0 0 rg BT 442.04 432.10 Td (o*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.04 432.10 Td (/) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 454.82 432.10 Td (A) Tj ET Q q 0 0 0 rg BT 460.38 432.10 Td (valide*.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.31 432.10 Td ( ) Tj ET Q q 0 0 0 rg BT 495.38 432.10 Td (Ef) Tj ET Q q 0 0 0 rg BT 504.64 432.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 534.91 432.10 Td (January 1, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 420.10 Td (2013, ) Tj ET Q q 0 0 0 rg BT 61.46 420.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 90.52 420.10 Td (assumed ) Tj ET Q q 0 0 0 rg BT 127.92 420.10 Td (essentially ) Tj ET Q q 0 0 0 rg BT 173.08 420.10 Td (all ) Tj ET Q q 0 0 0 rg BT 186.04 420.10 Td (of ) Tj ET Q q 0 0 0 rg BT 197.32 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 212.50 420.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 258.22 420.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 302.83 420.10 Td (of ) Tj ET Q q 0 0 0 rg BT 314.12 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 329.29 420.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 363.34 420.10 Td (with ) Tj ET Q q 0 0 0 rg BT 384.07 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 399.25 420.10 Td (exception ) Tj ET Q q 0 0 0 rg BT 441.08 420.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 452.36 420.10 Td (Plavix*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.90 420.10 Td ( ) Tj ET Q q 0 0 0 rg BT 485.86 420.10 Td (in ) Tj ET Q q 0 0 0 rg BT 496.60 420.10 Td (the ) Tj ET Q q 0 0 0 rg BT 511.77 420.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 532.51 420.10 Td (and ) Tj ET Q q 0 0 0 rg BT 549.90 420.10 Td (Puerto ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 408.10 Td (Rico ) Tj ET Q q 0 0 0 rg BT 56.81 408.10 Td (where ) Tj ET Q q 0 0 0 rg BT 83.17 408.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 106.21 408.10 Td (is ) Tj ET Q q 0 0 0 rg BT 114.81 408.10 Td (the ) Tj ET Q q 0 0 0 rg BT 128.95 408.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 168.64 408.10 Td (partner ) Tj ET Q q 0 0 0 rg BT 198.88 408.10 Td (with ) Tj ET Q q 0 0 0 rg BT 218.58 408.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 224.95 408.10 Td (50.1%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 250.78 408.10 Td ( ) Tj ET Q q 0 0 0 rg BT 252.70 408.10 Td (controlling ) Tj ET Q q 0 0 0 rg BT 298.51 408.10 Td (interest. ) Tj ET Q q 0 0 0 rg BT 332.37 408.10 Td (In ) Tj ET Q q 0 0 0 rg BT 342.63 408.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 382.30 408.10 Td (for ) Tj ET Q q 0 0 0 rg BT 395.89 408.10 Td (the ) Tj ET Q q 0 0 0 rg BT 410.03 408.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 434.74 408.10 Td (transferred ) Tj ET Q q 0 0 0 rg BT 479.97 408.10 Td (to ) Tj ET Q q 0 0 0 rg BT 489.67 408.10 Td (Sanofi, ) Tj ET Q q 0 0 0 rg BT 520.20 408.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 543.25 408.10 Td (receives ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 396.10 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 74.02 396.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 110.38 396.10 Td (from ) Tj ET Q q 0 0 0 rg BT 131.74 396.10 Td (January 1, ) Tj ET Q q 0 0 0 rg BT 174.77 396.10 Td (2013 ) Tj ET Q q 0 0 0 rg BT 196.69 396.10 Td (until ) Tj ET Q q 0 0 0 rg BT 216.95 396.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 274.96 396.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 296.89 396.10 Td (and ) Tj ET Q q 0 0 0 rg BT 313.25 396.10 Td (a ) Tj ET Q q 0 0 0 rg BT 319.61 396.10 Td (terminal ) Tj ET Q q 0 0 0 rg BT 354.86 396.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 391.22 396.10 Td (from ) Tj ET Q q 0 0 0 rg BT 412.58 396.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 440.62 396.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.87 396.10 Td ($200 ) Tj ET Q q 0 0 0 rg BT 472.80 396.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.69 396.10 Td ( ) Tj ET Q q 0 0 0 rg BT 503.61 396.10 Td (at ) Tj ET Q q 0 0 0 rg BT 512.75 396.10 Td (the ) Tj ET Q q 0 0 0 rg BT 526.90 396.10 Td (end ) Tj ET Q q 0 0 0 rg BT 543.26 396.10 Td (of ) Tj ET Q q 0 0 0 rg BT 553.52 396.10 Td (2018. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 384.10 Td (As ) Tj ET Q q 0 0 0 rg BT 49.64 384.10 Td (a ) Tj ET Q q 0 0 0 rg BT 56.61 384.10 Td (result ) Tj ET Q q 0 0 0 rg BT 81.36 384.10 Td (of ) Tj ET Q q 0 0 0 rg BT 92.22 384.10 Td (the ) Tj ET Q q 0 0 0 rg BT 106.96 384.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 144.49 384.10 Td (of ) Tj ET Q q 0 0 0 rg BT 154.79 384.10 Td (ASC ) Tj ET Q q 0 0 0 rg BT 176.77 384.10 Td (606 ) Tj ET Q q 0 0 0 rg BT 194.30 384.10 Td (in ) Tj ET Q q 0 0 0 rg BT 204.61 384.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 229.64 384.10 Td (future ) Tj ET Q q 0 0 0 rg BT 256.04 384.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 293.01 384.10 Td (will ) Tj ET Q q 0 0 0 rg BT 311.09 384.10 Td (no ) Tj ET Q q 0 0 0 rg BT 323.62 384.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 351.70 384.10 Td (be ) Tj ET Q q 0 0 0 rg BT 363.66 384.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 401.17 384.10 Td (in ) Tj ET Q q 0 0 0 rg BT 411.48 384.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 445.10 384.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 483.16 384.10 Td (and ) Tj ET Q q 0 0 0 rg BT 500.13 384.10 Td (will ) Tj ET Q q 0 0 0 rg BT 518.22 384.10 Td (be ) Tj ET Q q 0 0 0 rg BT 530.18 384.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 567.69 384.10 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 372.10 Td (a ) Tj ET Q q 0 0 0 rg BT 43.66 372.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 91.30 372.10 Td (ef) Tj ET Q q 0 0 0 rg BT 98.89 372.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 117.09 372.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 164.19 372.10 Td (in ) Tj ET Q q 0 0 0 rg BT 175.19 372.10 Td (the ) Tj ET Q q 0 0 0 rg BT 190.62 372.10 Td (first ) Tj ET Q q 0 0 0 rg BT 209.95 372.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 241.48 372.10 Td (of ) Tj ET Q q 0 0 0 rg BT 253.03 372.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 276.25 372.10 Td (with ) Tj ET Q q 0 0 0 rg BT 297.25 372.10 Td (a ) Tj ET Q q 0 0 0 rg BT 304.90 372.10 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 365.33 372.10 Td (contract ) Tj ET Q q 0 0 0 rg BT 400.75 372.10 Td (asset. ) Tj ET Q q 0 0 0 rg BT 425.90 372.10 Td (In ) Tj ET Q q 0 0 0 rg BT 437.45 372.10 Td (addition, ) Tj ET Q q 0 0 0 rg BT 475.94 372.10 Td (a ) Tj ET Q q 0 0 0 rg BT 483.60 372.10 Td (portion ) Tj ET Q q 0 0 0 rg BT 515.70 372.10 Td (of ) Tj ET Q q 0 0 0 rg BT 527.25 372.10 Td (the ) Tj ET Q q 0 0 0 rg BT 542.68 372.10 Td (terminal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 360.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 72.93 360.10 Td (will ) Tj ET Q q 0 0 0 rg BT 90.99 360.10 Td (be ) Tj ET Q q 0 0 0 rg BT 102.93 360.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 140.40 360.10 Td (as ) Tj ET Q q 0 0 0 rg BT 151.23 360.10 Td (a ) Tj ET Q q 0 0 0 rg BT 158.17 360.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 205.10 360.10 Td (ef) Tj ET Q q 0 0 0 rg BT 212.69 360.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 230.17 360.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 276.56 360.10 Td (in ) Tj ET Q q 0 0 0 rg BT 286.83 360.10 Td (the ) Tj ET Q q 0 0 0 rg BT 301.55 360.10 Td (first ) Tj ET Q q 0 0 0 rg BT 320.16 360.10 Td (quarter ) Tj ET Q q 0 0 0 rg BT 350.98 360.10 Td (of ) Tj ET Q q 0 0 0 rg BT 361.81 360.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 384.31 360.10 Td (with ) Tj ET Q q 0 0 0 rg BT 404.58 360.10 Td (a ) Tj ET Q q 0 0 0 rg BT 411.52 360.10 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 471.23 360.10 Td (contract ) Tj ET Q q 0 0 0 rg BT 505.93 360.10 Td (asset.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 336.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 76.20 336.10 Td (received ) Tj ET Q q 0 0 0 rg BT 112.49 336.10 Td (from ) Tj ET Q q 0 0 0 rg BT 134.35 336.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 162.89 336.10 Td (in ) Tj ET Q q 0 0 0 rg BT 173.09 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 187.74 336.10 Td (territory ) Tj ET Q q 0 0 0 rg BT 222.93 336.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 260.34 336.10 Td (the ) Tj ET Q q 0 0 0 rg BT 274.45 336.10 Td (Americas ) Tj ET Q q 0 0 0 rg BT 315.19 336.10 Td (and ) Tj ET Q q 0 0 0 rg BT 331.52 336.10 Td (Australia, ) Tj ET Q q 0 0 0 rg BT 373.10 336.10 Td (opt-out ) Tj ET Q q 0 0 0 rg BT 404.42 336.10 Td (markets, ) Tj ET Q q 0 0 0 rg BT 441.00 336.10 Td (and ) Tj ET Q q 0 0 0 rg BT 457.86 336.10 Td (former ) Tj ET Q q 0 0 0 rg BT 487.50 336.10 Td (development ) Tj ET Q q 0 0 0 rg BT 541.57 336.10 Td (royalties ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 324.10 Td (are ) Tj ET Q q 0 0 0 rg BT 50.88 324.10 Td (presented ) Tj ET Q q 0 0 0 rg BT 91.86 324.10 Td (in ) Tj ET Q q 0 0 0 rg BT 102.31 324.10 Td (alliance ) Tj ET Q q 0 0 0 rg BT 136.06 324.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 174.27 324.10 Td (and ) Tj ET Q q 0 0 0 rg BT 191.38 324.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.47 324.10 Td ($200 ) Tj ET Q q 0 0 0 rg BT 236.14 324.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 265.03 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 267.70 324.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 278.15 324.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.15 324.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.32 324.10 Td ($195 ) Tj ET Q q 0 0 0 rg BT 325.99 324.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.88 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 357.55 324.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.99 324.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.99 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 390.66 324.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.77 324.10 Td ($21) Tj ET Q q 0 0 0 rg BT 422.40 324.10 Td (1 ) Tj ET Q q 0 0 0 rg BT 430.06 324.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.96 324.10 Td ( ) Tj ET Q q 0 0 0 rg BT 461.63 324.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.07 324.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.07 324.10 Td (. ) Tj ET Q q 0 0 0 rg BT 497.24 324.10 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 537.68 324.10 Td (attributed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 312.10 Td (to ) Tj ET Q q 0 0 0 rg BT 46.45 312.10 Td (the ) Tj ET Q q 0 0 0 rg BT 61.33 312.10 Td (territory ) Tj ET Q q 0 0 0 rg BT 96.76 312.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 134.41 312.10 Td (Europe ) Tj ET Q q 0 0 0 rg BT 165.96 312.10 Td (and ) Tj ET Q q 0 0 0 rg BT 182.48 312.10 Td (Asia ) Tj ET Q q 0 0 0 rg BT 203.47 312.10 Td (continue ) Tj ET Q q 0 0 0 rg BT 240.57 312.10 Td (to ) Tj ET Q q 0 0 0 rg BT 251.02 312.10 Td (be ) Tj ET Q q 0 0 0 rg BT 263.13 312.10 Td (earned ) Tj ET Q q 0 0 0 rg BT 292.44 312.10 Td (by ) Tj ET Q q 0 0 0 rg BT 305.11 312.10 Td (the ) Tj ET Q q 0 0 0 rg BT 319.99 312.10 Td (territory ) Tj ET Q q 0 0 0 rg BT 355.42 312.10 Td (partnership ) Tj ET Q q 0 0 0 rg BT 403.07 312.10 Td (and ) Tj ET Q q 0 0 0 rg BT 420.18 312.10 Td (are ) Tj ET Q q 0 0 0 rg BT 435.06 312.10 Td (included ) Tj ET Q q 0 0 0 rg BT 472.16 312.10 Td (in ) Tj ET Q q 0 0 0 rg BT 482.60 312.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 510.26 312.10 Td (in ) Tj ET Q q 0 0 0 rg BT 520.71 312.10 Td (net ) Tj ET Q q 0 0 0 rg BT 535.59 312.10 Td (income ) Tj ET Q q 0 0 0 rg BT 567.70 312.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 300.10 Td (af) Tj ET Q q 0 0 0 rg BT 43.59 300.10 Td (filiates. ) Tj ET Q q 0 0 0 rg BT 75.25 300.10 Td (Alliance ) Tj ET Q q 0 0 0 rg BT 111.62 300.10 Td (revenues ) Tj ET Q q 0 0 0 rg BT 149.66 300.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 190.48 300.10 Td (to ) Tj ET Q q 0 0 0 rg BT 200.76 300.10 Td (the ) Tj ET Q q 0 0 0 rg BT 215.47 300.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 244.64 300.10 Td (of ) Tj ET Q q 0 0 0 rg BT 255.47 300.10 Td (irbesartan ) Tj ET Q q 0 0 0 rg BT 296.84 300.10 Td (API ) Tj ET Q q 0 0 0 rg BT 315.46 300.10 Td (to ) Tj ET Q q 0 0 0 rg BT 325.74 300.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 354.34 300.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 376.27 300.10 Td ($80 ) Tj ET Q q 0 0 0 rg BT 393.77 300.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.67 300.10 Td ( ) Tj ET Q q 0 0 0 rg BT 425.17 300.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.44 300.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.44 300.10 Td (. ) Tj ET Q endstream endobj 147 0 obj <> endobj 148 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (73) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Summarized financial information related to this alliance was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 712.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 712.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 712.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 686.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 686.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 686.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 660.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 660.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 660.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 634.60 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 634.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 634.60 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 634.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 634.60 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 725.6 m 448.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 725.6 m 452.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 725.6 m 512.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 725.6 m 516.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 725.6 m 576.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 712.6 m 448.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 712.6 m 512.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 712.6 m 576.5 712.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 673.6 m 448.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 661.6 m 448.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 659.6 m 448.5 659.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 673.6 m 512.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 661.6 m 512.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 659.6 m 512.5 659.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 673.6 m 576.5 673.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 661.6 m 576.5 661.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 659.6 m 576.5 659.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 729.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 729.83 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 729.83 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 729.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 729.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 716.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 716.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 716.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 716.83 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 703.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.73 703.33 Td (om Sanofi alliances:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 690.17 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 690.17 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 690.17 Td (38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 690.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 690.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 690.17 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 677.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 677.17 Td (207) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 677.17 Td (200) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 677.17 Td (296) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.00 664.17 Td (T) Tj ET Q q 0 0 0 rg BT 50.41 664.17 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 664.17 Td (234) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 664.17 Td (238) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 664.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 664.17 Td (406) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 638.33 Td (Payments to/\(fr) Tj ET Q q 0 0 0 rg BT 105.19 638.33 Td (om\) Sanofi:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 625.17 Td (Equity in net income of af) Tj ET Q q 0 0 0 rg BT 143.60 625.17 Td (filiates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.30 625.22 Td (\(95) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.65 625.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.30 625.22 Td (\(95) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 625.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 625.17 Td (\(104) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 625.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 612.17 Td (Noncontrolling interest – pretax) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 612.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 612.17 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 612.17 Td (51) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 585.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.61 585.10 Td (following ) Tj ET Q q 0 0 0 rg BT 96.56 585.10 Td (is ) Tj ET Q q 0 0 0 rg BT 106.30 585.10 Td (summarized ) Tj ET Q q 0 0 0 rg BT 158.23 585.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 196.28 585.10 Td (information ) Tj ET Q q 0 0 0 rg BT 246.55 585.10 Td (for ) Tj ET Q q 0 0 0 rg BT 261.28 585.10 Td (interests ) Tj ET Q q 0 0 0 rg BT 297.67 585.10 Td (in ) Tj ET Q q 0 0 0 rg BT 308.51 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 323.79 585.10 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 375.73 585.10 Td (with ) Tj ET Q q 0 0 0 rg BT 396.57 585.10 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 425.74 585.10 Td (for ) Tj ET Q q 0 0 0 rg BT 440.47 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 455.75 585.10 Td (territory ) Tj ET Q q 0 0 0 rg BT 491.58 585.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 529.63 585.10 Td (Europe ) Tj ET Q q 0 0 0 rg BT 561.57 585.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 573.10 Td (Asia, ) Tj ET Q q 0 0 0 rg BT 59.33 573.10 Td (which ) Tj ET Q q 0 0 0 rg BT 86.27 573.10 Td (are ) Tj ET Q q 0 0 0 rg BT 100.98 573.10 Td (not ) Tj ET Q q 0 0 0 rg BT 116.25 573.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 169.30 573.10 Td (but ) Tj ET Q q 0 0 0 rg BT 184.57 573.10 Td (are ) Tj ET Q q 0 0 0 rg BT 199.28 573.10 Td (accounted ) Tj ET Q q 0 0 0 rg BT 242.31 573.10 Td (for ) Tj ET Q q 0 0 0 rg BT 256.47 573.10 Td (using ) Tj ET Q q 0 0 0 rg BT 280.64 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 295.36 573.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 322.86 573.10 Td (method:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 536.60 348.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 536.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 536.60 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 536.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 536.60 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 536.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 536.60 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 512.60 348.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 512.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 512.60 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 512.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 512.60 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 512.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 512.60 60.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 549.6 m 448.5 549.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 549.6 m 452.5 549.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 549.6 m 512.5 549.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 549.6 m 516.5 549.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 549.6 m 576.5 549.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 536.6 m 448.5 536.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 536.6 m 512.5 536.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 536.6 m 576.5 536.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 553.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 553.83 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 553.83 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 553.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 553.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 540.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 540.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 540.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 540.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 527.22 Td (Net sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 527.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 527.22 Td (231) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 527.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 527.22 Td (235) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 527.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 527.22 Td (257) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 515.22 Td (Gross profit) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 515.22 Td (192) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 515.22 Td (195) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 515.22 Td (213) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 503.22 Td (Net income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 503.22 Td (189) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 503.22 Td (192) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 503.22 Td (209) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 475.53505859375 m 54.33984375 475.53505859375 l s q 0 0 0 rg BT 36.00 477.10 Td (Ono) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.73 453.10 Td (is ) Tj ET Q q 0 0 0 rg BT 69.00 453.10 Td (the ) Tj ET Q q 0 0 0 rg BT 83.82 453.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 121.97 453.10 Td (in ) Tj ET Q q 0 0 0 rg BT 132.35 453.10 Td (the ) Tj ET Q q 0 0 0 rg BT 147.18 453.10 Td (end ) Tj ET Q q 0 0 0 rg BT 164.22 453.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 203.48 453.10 Td (product ) Tj ET Q q 0 0 0 rg BT 236.63 453.10 Td (sales ) Tj ET Q q 0 0 0 rg BT 258.68 453.10 Td (and ) Tj ET Q q 0 0 0 rg BT 275.72 453.10 Td (has ) Tj ET Q q 0 0 0 rg BT 291.65 453.10 Td (the ) Tj ET Q q 0 0 0 rg BT 306.48 453.10 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 346.84 453.10 Td (right ) Tj ET Q q 0 0 0 rg BT 368.34 453.10 Td (to ) Tj ET Q q 0 0 0 rg BT 378.72 453.10 Td (develop, ) Tj ET Q q 0 0 0 rg BT 415.48 453.10 Td (manufacture ) Tj ET Q q 0 0 0 rg BT 468.06 453.10 Td (and ) Tj ET Q q 0 0 0 rg BT 485.10 453.10 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 546.56 453.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 576.00 453.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 80.64 441.10 Td (except ) Tj ET Q q 0 0 0 rg BT 108.61 441.10 Td (in ) Tj ET Q q 0 0 0 rg BT 118.26 441.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 145.41 441.10 Td (South ) Tj ET Q q 0 0 0 rg BT 170.62 441.10 Td (Korea ) Tj ET Q q 0 0 0 rg BT 196.92 441.10 Td (and ) Tj ET Q q 0 0 0 rg BT 213.10 441.10 Td (T) Tj ET Q q 0 0 0 rg BT 218.51 441.10 Td (aiwan. ) Tj ET Q q 0 0 0 rg BT 246.76 441.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 265.86 441.10 Td (is ) Tj ET Q q 0 0 0 rg BT 274.40 441.10 Td (entitled ) Tj ET Q q 0 0 0 rg BT 306.26 441.10 Td (to ) Tj ET Q q 0 0 0 rg BT 315.92 441.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 346.65 441.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 382.96 441.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 393.16 441.10 Td (4%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.49 441.10 Td ( ) Tj ET Q q 0 0 0 rg BT 408.37 441.10 Td (in ) Tj ET Q q 0 0 0 rg BT 418.02 441.10 Td (North ) Tj ET Q q 0 0 0 rg BT 442.81 441.10 Td (America ) Tj ET Q q 0 0 0 rg BT 479.11 441.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.42 441.10 Td (15%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.75 441.10 Td ( ) Tj ET Q q 0 0 0 rg BT 515.63 441.10 Td (in ) Tj ET Q q 0 0 0 rg BT 525.28 441.10 Td (all ) Tj ET Q q 0 0 0 rg BT 537.15 441.10 Td (territories ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 429.10 Td (excluding ) Tj ET Q q 0 0 0 rg BT 77.93 429.10 Td (the ) Tj ET Q q 0 0 0 rg BT 92.65 429.10 Td (three ) Tj ET Q q 0 0 0 rg BT 115.14 429.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 154.29 429.10 Td (listed ) Tj ET Q q 0 0 0 rg BT 178.46 429.10 Td (above, ) Tj ET Q q 0 0 0 rg BT 207.33 429.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 238.16 429.10 Td (to ) Tj ET Q q 0 0 0 rg BT 248.44 429.10 Td (customary ) Tj ET Q q 0 0 0 rg BT 292.59 429.10 Td (adjustments.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.93 405.10 Td (and ) Tj ET Q q 0 0 0 rg BT 77.17 405.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 97.20 405.10 Td (jointly ) Tj ET Q q 0 0 0 rg BT 126.12 405.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 160.58 405.10 Td (and ) Tj ET Q q 0 0 0 rg BT 177.82 405.10 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 239.48 405.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.92 405.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 274.22 405.10 Td (Y) Tj ET Q q 0 0 0 rg BT 278.87 405.10 Td (ervoy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.07 405.10 Td ( ) Tj ET Q q 0 0 0 rg BT 303.88 405.10 Td (and ) Tj ET Q q 0 0 0 rg BT 321.12 405.10 Td (several ) Tj ET Q q 0 0 0 rg BT 352.24 405.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 376.17 405.10 Td (investigational ) Tj ET Q q 0 0 0 rg BT 437.85 405.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 486.77 405.10 Td (in ) Tj ET Q q 0 0 0 rg BT 497.35 405.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 525.42 405.10 Td (South ) Tj ET Q q 0 0 0 rg BT 551.57 405.10 Td (Korea ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 393.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.58 393.10 Td (T) Tj ET Q q 0 0 0 rg BT 57.99 393.10 Td (aiwan. ) Tj ET Q q 0 0 0 rg BT 86.69 393.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 110.12 393.10 Td (is ) Tj ET Q q 0 0 0 rg BT 119.10 393.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 166.97 393.10 Td (for ) Tj ET Q q 0 0 0 rg BT 180.94 393.10 Td (supply ) Tj ET Q q 0 0 0 rg BT 209.92 393.10 Td (of ) Tj ET Q q 0 0 0 rg BT 220.57 393.10 Td (the ) Tj ET Q q 0 0 0 rg BT 235.10 393.10 Td (products. ) Tj ET Q q 0 0 0 rg BT 274.35 393.10 Td (Profits, ) Tj ET Q q 0 0 0 rg BT 305.83 393.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 332.04 393.10 Td (and ) Tj ET Q q 0 0 0 rg BT 348.79 393.10 Td (development ) Tj ET Q q 0 0 0 rg BT 402.75 393.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 425.07 393.10 Td (are ) Tj ET Q q 0 0 0 rg BT 439.59 393.10 Td (shared ) Tj ET Q q 0 0 0 rg BT 468.00 393.10 Td (equally ) Tj ET Q q 0 0 0 rg BT 499.75 393.10 Td (for ) Tj ET Q q 0 0 0 rg BT 513.72 393.10 Td (all ) Tj ET Q q 0 0 0 rg BT 526.03 393.10 Td (combination ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 381.10 Td (therapies ) Tj ET Q q 0 0 0 rg BT 75.64 381.10 Td (involving ) Tj ET Q q 0 0 0 rg BT 117.52 381.10 Td (compounds ) Tj ET Q q 0 0 0 rg BT 167.17 381.10 Td (of ) Tj ET Q q 0 0 0 rg BT 179.04 381.10 Td (both ) Tj ET Q q 0 0 0 rg BT 200.37 381.10 Td (parties. ) Tj ET Q q 0 0 0 rg BT 233.06 381.10 Td (Otherwise, ) Tj ET Q q 0 0 0 rg BT 280.21 381.10 Td (sharing ) Tj ET Q q 0 0 0 rg BT 313.19 381.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.40 381.10 Td (80%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 341.73 381.10 Td ( ) Tj ET Q q 0 0 0 rg BT 345.28 381.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.26 381.10 Td (20%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.59 381.10 Td ( ) Tj ET Q q 0 0 0 rg BT 385.13 381.10 Td (for ) Tj ET Q q 0 0 0 rg BT 400.34 381.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 439.98 381.10 Td (involving ) Tj ET Q q 0 0 0 rg BT 481.86 381.10 Td (only ) Tj ET Q q 0 0 0 rg BT 503.18 381.10 Td (one ) Tj ET Q q 0 0 0 rg BT 521.16 381.10 Td (of ) Tj ET Q q 0 0 0 rg BT 533.04 381.10 Td (the ) Tj ET Q q 0 0 0 rg BT 548.80 381.10 Td (party’) Tj ET Q q 0 0 0 rg BT 572.12 381.10 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.10 Td (compounds. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.36 345.10 Td (and ) Tj ET Q q 0 0 0 rg BT 76.03 345.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 95.48 345.10 Td (also ) Tj ET Q q 0 0 0 rg BT 113.82 345.10 Td (jointly ) Tj ET Q q 0 0 0 rg BT 142.17 345.10 Td (develop ) Tj ET Q q 0 0 0 rg BT 176.06 345.10 Td (and ) Tj ET Q q 0 0 0 rg BT 192.73 345.10 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 253.81 345.10 Td (Or) Tj ET Q q 0 0 0 rg BT 264.56 345.10 Td (encia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 286.21 345.10 Td ( ) Tj ET Q q 0 0 0 rg BT 288.44 345.10 Td (in ) Tj ET Q q 0 0 0 rg BT 298.46 345.10 Td (Japan. ) Tj ET Q q 0 0 0 rg BT 325.96 345.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 349.31 345.10 Td (is ) Tj ET Q q 0 0 0 rg BT 358.22 345.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 406.00 345.10 Td (for ) Tj ET Q q 0 0 0 rg BT 419.89 345.10 Td (the ) Tj ET Q q 0 0 0 rg BT 434.34 345.10 Td (order ) Tj ET Q q 0 0 0 rg BT 457.67 345.10 Td (fulfillment ) Tj ET Q q 0 0 0 rg BT 502.67 345.10 Td (and ) Tj ET Q q 0 0 0 rg BT 519.34 345.10 Td (distribution ) Tj ET Q q 0 0 0 rg BT 567.69 345.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 51.02 333.10 Td (intravenous ) Tj ET Q q 0 0 0 rg BT 100.47 333.10 Td (formulation ) Tj ET Q q 0 0 0 rg BT 150.48 333.10 Td (and ) Tj ET Q q 0 0 0 rg BT 167.72 333.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 187.75 333.10 Td (is ) Tj ET Q q 0 0 0 rg BT 197.22 333.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 245.56 333.10 Td (for ) Tj ET Q q 0 0 0 rg BT 260.02 333.10 Td (the ) Tj ET Q q 0 0 0 rg BT 275.04 333.10 Td (subcutaneous ) Tj ET Q q 0 0 0 rg BT 331.72 333.10 Td (formulation. ) Tj ET Q q 0 0 0 rg BT 384.23 333.10 Td (Both ) Tj ET Q q 0 0 0 rg BT 406.48 333.10 Td (formulations ) Tj ET Q q 0 0 0 rg BT 460.38 333.10 Td (are ) Tj ET Q q 0 0 0 rg BT 475.39 333.10 Td (jointly ) Tj ET Q q 0 0 0 rg BT 504.30 333.10 Td (promoted ) Tj ET Q q 0 0 0 rg BT 545.43 333.10 Td (by ) Tj ET Q q 0 0 0 rg BT 558.23 333.10 Td (both ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 321.10 Td (parties ) Tj ET Q q 0 0 0 rg BT 65.10 321.10 Td (with ) Tj ET Q q 0 0 0 rg BT 85.33 321.10 Td (assigned ) Tj ET Q q 0 0 0 rg BT 122.21 321.10 Td (customer ) Tj ET Q q 0 0 0 rg BT 161.31 321.10 Td (accounts ) Tj ET Q q 0 0 0 rg BT 198.74 321.10 Td (and ) Tj ET Q q 0 0 0 rg BT 215.63 321.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 239.20 321.10 Td (is ) Tj ET Q q 0 0 0 rg BT 248.31 321.10 Td (responsible ) Tj ET Q q 0 0 0 rg BT 296.31 321.10 Td (for ) Tj ET Q q 0 0 0 rg BT 310.41 321.10 Td (the ) Tj ET Q q 0 0 0 rg BT 325.08 321.10 Td (product ) Tj ET Q q 0 0 0 rg BT 358.07 321.10 Td (supply) Tj ET Q q 0 0 0 rg BT 384.09 321.10 Td (. ) Tj ET Q q 0 0 0 rg BT 388.50 321.10 Td (A) Tj ET Q q 0 0 0 rg BT 395.17 321.10 Td ( ) Tj ET Q q 0 0 0 rg BT 397.61 321.10 Td (co-promotion ) Tj ET Q q 0 0 0 rg BT 454.49 321.10 Td (fee ) Tj ET Q q 0 0 0 rg BT 469.15 321.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.92 321.10 Td (60%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.25 321.10 Td ( ) Tj ET Q q 0 0 0 rg BT 500.70 321.10 Td (is ) Tj ET Q q 0 0 0 rg BT 509.82 321.10 Td (paid ) Tj ET Q q 0 0 0 rg BT 529.48 321.10 Td (when ) Tj ET Q q 0 0 0 rg BT 553.58 321.10 Td (a ) Tj ET Q q 0 0 0 rg BT 560.47 321.10 Td (sale ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.10 Td (is ) Tj ET Q q 0 0 0 rg BT 45.17 309.10 Td (made ) Tj ET Q q 0 0 0 rg BT 69.33 309.10 Td (to ) Tj ET Q q 0 0 0 rg BT 79.60 309.10 Td (the ) Tj ET Q q 0 0 0 rg BT 94.32 309.10 Td (other ) Tj ET Q q 0 0 0 rg BT 117.37 309.10 Td (party’) Tj ET Q q 0 0 0 rg BT 140.69 309.10 Td (s ) Tj ET Q q 0 0 0 rg BT 147.08 309.10 Td (assigned ) Tj ET Q q 0 0 0 rg BT 184.02 309.10 Td (customer) Tj ET Q q 0 0 0 rg BT 220.13 309.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.10 Td (In ) Tj ET Q q 0 0 0 rg BT 47.61 285.10 Td (2017, ) Tj ET Q q 0 0 0 rg BT 73.38 285.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 93.88 285.10 Td (granted ) Tj ET Q q 0 0 0 rg BT 127.14 285.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 151.54 285.10 Td (an ) Tj ET Q q 0 0 0 rg BT 164.25 285.10 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 205.29 285.10 Td (license ) Tj ET Q q 0 0 0 rg BT 236.33 285.10 Td (for ) Tj ET Q q 0 0 0 rg BT 251.26 285.10 Td (the ) Tj ET Q q 0 0 0 rg BT 266.76 285.10 Td (development ) Tj ET Q q 0 0 0 rg BT 321.68 285.10 Td (and ) Tj ET Q q 0 0 0 rg BT 339.40 285.10 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 417.08 285.10 Td (of ) Tj ET Q q 0 0 0 rg BT 428.69 285.10 Td (ONO-4578, ) Tj ET Q q 0 0 0 rg BT 479.46 285.10 Td (Ono’) Tj ET Q q 0 0 0 rg BT 499.46 285.10 Td (s ) Tj ET Q q 0 0 0 rg BT 506.62 285.10 Td (Prostaglandin ) Tj ET Q q 0 0 0 rg BT 564.89 285.10 Td (E2 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.10 Td (receptor ) Tj ET Q q 0 0 0 rg BT 71.93 273.10 Td (4 ) Tj ET Q q 0 0 0 rg BT 80.11 273.10 Td (antagonist. ) Tj ET Q q 0 0 0 rg BT 126.89 273.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 151.20 273.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 188.80 273.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 234.75 273.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 260.70 273.10 Td (except ) Tj ET Q q 0 0 0 rg BT 289.97 273.10 Td (in ) Tj ET Q q 0 0 0 rg BT 300.93 273.10 Td (Japan, ) Tj ET Q q 0 0 0 rg BT 329.38 273.10 Td (South ) Tj ET Q q 0 0 0 rg BT 355.90 273.10 Td (Korea, ) Tj ET Q q 0 0 0 rg BT 386.00 273.10 Td (and ) Tj ET Q q 0 0 0 rg BT 403.39 273.10 Td (T) Tj ET Q q 0 0 0 rg BT 408.80 273.10 Td (aiwan ) Tj ET Q q 0 0 0 rg BT 435.86 273.10 Td (where ) Tj ET Q q 0 0 0 rg BT 463.47 273.10 Td (it ) Tj ET Q q 0 0 0 rg BT 472.20 273.10 Td (was ) Tj ET Q q 0 0 0 rg BT 490.93 273.10 Td (added ) Tj ET Q q 0 0 0 rg BT 517.99 273.10 Td (to ) Tj ET Q q 0 0 0 rg BT 528.94 273.10 Td (the ) Tj ET Q q 0 0 0 rg BT 544.34 273.10 Td (existing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 261.10 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 90.56 261.10 Td (and ) Tj ET Q q 0 0 0 rg BT 106.80 261.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.39 261.10 Td (China ) Tj ET Q q 0 0 0 rg BT 142.08 261.10 Td (and ) Tj ET Q q 0 0 0 rg BT 157.92 261.10 Td (ASEAN ) Tj ET Q q 0 0 0 rg BT 193.06 261.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 231.52 261.10 Td (where ) Tj ET Q q 0 0 0 rg BT 257.75 261.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 276.77 261.10 Td (retained ) Tj ET Q q 0 0 0 rg BT 310.78 261.10 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 350.34 261.10 Td (rights. ) Tj ET Q q 0 0 0 rg BT 377.43 261.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 400.35 261.10 Td (paid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.37 261.10 Td ($40 ) Tj ET Q q 0 0 0 rg BT 436.18 261.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.07 261.10 Td ( ) Tj ET Q q 0 0 0 rg BT 466.87 261.10 Td (to ) Tj ET Q q 0 0 0 rg BT 476.45 261.10 Td (Ono, ) Tj ET Q q 0 0 0 rg BT 497.98 261.10 Td (which ) Tj ET Q q 0 0 0 rg BT 524.22 261.10 Td (was ) Tj ET Q q 0 0 0 rg BT 541.57 261.10 Td (included ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 249.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.62 249.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 71.13 249.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 106.17 249.10 Td (in ) Tj ET Q q 0 0 0 rg BT 116.79 249.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 142.13 249.10 Td (Ono ) Tj ET Q q 0 0 0 rg BT 162.19 249.10 Td (is ) Tj ET Q q 0 0 0 rg BT 171.70 249.10 Td (eligible ) Tj ET Q q 0 0 0 rg BT 204.53 249.10 Td (to ) Tj ET Q q 0 0 0 rg BT 215.15 249.10 Td (receive ) Tj ET Q q 0 0 0 rg BT 246.85 249.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 294.13 249.10 Td (clinical, ) Tj ET Q q 0 0 0 rg BT 328.90 249.10 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 372.83 249.10 Td (and ) Tj ET Q q 0 0 0 rg BT 390.11 249.10 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 438.48 249.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 480.20 249.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 521.37 249.10 Td (of ) Tj ET Q q 0 0 0 rg BT 532.54 249.10 Td (up ) Tj ET Q q 0 0 0 rg BT 545.38 249.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.00 249.10 Td ($480 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 237.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 237.10 Td ( ) Tj ET Q q 0 0 0 rg BT 67.39 237.10 Td (and ) Tj ET Q q 0 0 0 rg BT 84.33 237.10 Td (royalties ) Tj ET Q q 0 0 0 rg BT 121.26 237.10 Td (in ) Tj ET Q q 0 0 0 rg BT 131.54 237.10 Td (countries ) Tj ET Q q 0 0 0 rg BT 170.70 237.10 Td (where ) Tj ET Q q 0 0 0 rg BT 197.63 237.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 221.25 237.10 Td (has ) Tj ET Q q 0 0 0 rg BT 237.08 237.10 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 277.34 237.10 Td (licensing ) Tj ET Q q 0 0 0 rg BT 315.95 237.10 Td (rights.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.10 Td (Summarized financial information related to this alliance was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 176.60 357.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 392.50 176.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 396.50 176.60 57.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 453.50 176.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 457.50 176.60 57.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 176.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 176.60 57.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 150.60 357.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 392.50 150.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 396.50 150.60 57.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 453.50 150.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 457.50 150.60 57.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 514.50 150.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 150.60 57.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 189.60000000000002 m 453.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 453.5 189.60000000000002 m 457.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 189.60000000000002 m 514.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 514.5 189.60000000000002 m 518.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 189.60000000000002 m 575.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 189.60000000000002 m 453.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 176.60000000000002 m 453.5 176.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 453.5 189.60000000000002 m 457.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 189.60000000000002 m 514.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 176.60000000000002 m 514.5 176.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 514.5 189.60000000000002 m 518.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 189.60000000000002 m 575.5 189.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 176.60000000000002 m 575.5 176.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 137.60000000000002 m 453.5 137.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 125.60000000000002 m 453.5 125.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 396.5 123.60000000000002 m 453.5 123.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 137.60000000000002 m 514.5 137.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 125.60000000000002 m 514.5 125.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 457.5 123.60000000000002 m 514.5 123.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 137.60000000000002 m 575.5 137.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 125.60000000000002 m 575.5 125.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 123.60000000000002 m 575.5 123.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 193.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 441.20 193.83 Td (Y) Tj ET Q q 0 0 0 rg BT 446.53 193.83 Td (ear) Tj ET Q q 0 0 0 rg BT 457.12 193.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 517.85 193.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 180.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 416.50 180.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 477.50 180.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.50 180.83 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 167.33 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 88.64 167.33 Td (om Ono alliances:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 154.17 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.00 154.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 154.17 Td (145) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.00 154.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.65 154.17 Td (147) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.00 154.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 154.17 Td (1) Tj ET Q q 0 0 0 rg BT 561.65 154.17 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 141.17 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 141.17 Td (268) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.65 141.17 Td (280) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 141.17 Td (61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 44.00 128.17 Td (T) Tj ET Q q 0 0 0 rg BT 49.41 128.17 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.00 128.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 128.17 Td (413) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.00 128.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.65 128.17 Td (427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.00 128.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 128.17 Td (174) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 149 0 obj <> endobj 150 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (74) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 747.68505859375 m 68.412109375 747.68505859375 l s q 0 0 0 rg BT 36.00 749.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 61.20 749.25 Td (ie) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 58.95 725.25 Td (was ) Tj ET Q q 0 0 0 rg BT 76.32 725.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 108.13 725.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 147.72 725.25 Td (global ) Tj ET Q q 0 0 0 rg BT 174.54 725.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 199.14 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 208.74 725.25 Td (co-develop ) Tj ET Q q 0 0 0 rg BT 254.99 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 271.25 725.25 Td (commercialize ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 331.93 725.25 Td (Empliciti,) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.09 725.25 Td ( ) Tj ET Q q 0 0 0 rg BT 372.91 725.25 Td (a ) Tj ET Q q 0 0 0 rg BT 379.17 725.25 Td (humanized ) Tj ET Q q 0 0 0 rg BT 424.87 725.25 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 473.91 725.25 Td (antibody ) Tj ET Q q 0 0 0 rg BT 510.72 725.25 Td (for ) Tj ET Q q 0 0 0 rg BT 524.21 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 538.25 725.25 Td (treatment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 47.51 713.25 Td (multiple ) Tj ET Q q 0 0 0 rg BT 84.02 713.25 Td (myeloma ) Tj ET Q q 0 0 0 rg BT 124.42 713.25 Td (from ) Tj ET Q q 0 0 0 rg BT 147.04 713.25 Td (PDL) Tj ET Q q 0 0 0 rg BT 165.56 713.25 Td ( ) Tj ET Q q 0 0 0 rg BT 168.74 713.25 Td (BioPharma, ) Tj ET Q q 0 0 0 rg BT 219.41 713.25 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 237.86 713.25 Td (\(now ) Tj ET Q q 0 0 0 rg BT 261.60 713.25 Td (part ) Tj ET Q q 0 0 0 rg BT 280.32 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 291.13 713.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 314.98 713.25 Td (ie\). ) Tj ET Q q 0 0 0 rg BT 330.50 713.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 354.34 713.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 364.74 713.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 404.02 713.25 Td (participates ) Tj ET Q q 0 0 0 rg BT 453.29 713.25 Td (in ) Tj ET Q q 0 0 0 rg BT 464.25 713.25 Td (joint ) Tj ET Q q 0 0 0 rg BT 485.76 713.25 Td (development ) Tj ET Q q 0 0 0 rg BT 540.59 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 558.21 713.25 Td (U.S. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 112.86 701.25 Td (committees ) Tj ET Q q 0 0 0 rg BT 161.41 701.25 Td (in ) Tj ET Q q 0 0 0 rg BT 171.63 701.25 Td (which ) Tj ET Q q 0 0 0 rg BT 198.52 701.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 222.09 701.25 Td (has ) Tj ET Q q 0 0 0 rg BT 237.87 701.25 Td (final ) Tj ET Q q 0 0 0 rg BT 258.64 701.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 294.42 701.25 Td (making ) Tj ET Q q 0 0 0 rg BT 326.86 701.25 Td (authority) Tj ET Q q 0 0 0 rg BT 362.32 701.25 Td (. ) Tj ET Q q 0 0 0 rg BT 367.26 701.25 Td (Both ) Tj ET Q q 0 0 0 rg BT 389.16 701.25 Td (parties ) Tj ET Q q 0 0 0 rg BT 418.27 701.25 Td (jointly ) Tj ET Q q 0 0 0 rg BT 446.83 701.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 480.93 701.25 Td (the ) Tj ET Q q 0 0 0 rg BT 495.60 701.25 Td (product ) Tj ET Q q 0 0 0 rg BT 528.59 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 544.94 701.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 568.78 701.25 Td (ie ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (funds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 60.73 689.25 Td (20%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 79.06 689.25 Td ( ) Tj ET Q q 0 0 0 rg BT 81.57 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 92.41 689.25 Td (global ) Tj ET Q q 0 0 0 rg BT 119.91 689.25 Td (development ) Tj ET Q q 0 0 0 rg BT 174.07 689.25 Td (costs. ) Tj ET Q q 0 0 0 rg BT 199.08 689.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 222.71 689.25 Td (is ) Tj ET Q q 0 0 0 rg BT 231.89 689.25 Td (solely ) Tj ET Q q 0 0 0 rg BT 258.29 689.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 306.34 689.25 Td (for ) Tj ET Q q 0 0 0 rg BT 320.51 689.25 Td (supply) Tj ET Q q 0 0 0 rg BT 346.53 689.25 Td (, ) Tj ET Q q 0 0 0 rg BT 351.54 689.25 Td (distribution ) Tj ET Q q 0 0 0 rg BT 400.16 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 417.11 689.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 439.06 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 456.00 689.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 499.05 689.25 Td (activities ) Tj ET Q q 0 0 0 rg BT 537.66 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 554.61 689.25 Td (is ) Tj ET Q q 0 0 0 rg BT 563.79 689.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (principal ) Tj ET Q q 0 0 0 rg BT 74.24 677.25 Td (in ) Tj ET Q q 0 0 0 rg BT 84.73 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 99.65 677.25 Td (end ) Tj ET Q q 0 0 0 rg BT 116.79 677.25 Td (customer ) Tj ET Q q 0 0 0 rg BT 156.14 677.25 Td (product ) Tj ET Q q 0 0 0 rg BT 189.39 677.25 Td (sales. ) Tj ET Q q 0 0 0 rg BT 213.44 677.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 237.28 677.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 247.20 677.25 Td (shares ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 274.89 677.25 Td (30%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 293.22 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 295.93 677.25 Td (of ) Tj ET Q q 0 0 0 rg BT 306.96 677.25 Td (all ) Tj ET Q q 0 0 0 rg BT 319.66 677.25 Td (profits ) Tj ET Q q 0 0 0 rg BT 348.47 677.25 Td (and ) Tj ET Q q 0 0 0 rg BT 365.61 677.25 Td (losses ) Tj ET Q q 0 0 0 rg BT 392.20 677.25 Td (in ) Tj ET Q q 0 0 0 rg BT 402.68 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 417.60 677.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 438.09 677.25 Td (and ) Tj ET Q q 0 0 0 rg BT 455.23 677.25 Td (is ) Tj ET Q q 0 0 0 rg BT 464.60 677.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 484.52 677.25 Td (tiered ) Tj ET Q q 0 0 0 rg BT 509.99 677.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 547.12 677.25 Td (outside ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.29 665.25 Td (the ) Tj ET Q q 0 0 0 rg BT 60.47 665.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 80.21 665.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 103.29 665.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 122.04 665.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 145.88 665.25 Td (ie ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 155.06 665.25 Td ($140 ) Tj ET Q q 0 0 0 rg BT 177.02 665.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.91 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 207.87 665.25 Td (for ) Tj ET Q q 0 0 0 rg BT 221.49 665.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 250.66 665.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 293.71 665.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 334.55 665.25 Td (events ) Tj ET Q q 0 0 0 rg BT 362.06 665.25 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.79 665.25 Td ($52 ) Tj ET Q q 0 0 0 rg BT 418.75 665.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 447.65 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 449.61 665.25 Td (for ) Tj ET Q q 0 0 0 rg BT 463.23 665.25 Td (approval ) Tj ET Q q 0 0 0 rg BT 500.17 665.25 Td (milestones ) Tj ET Q q 0 0 0 rg BT 544.91 665.25 Td (through ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (December ) Tj ET Q q 0 0 0 rg BT 79.66 653.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 94.74 653.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 119.25 653.25 Td (AbbV) Tj ET Q q 0 0 0 rg BT 143.09 653.25 Td (ie ) Tj ET Q q 0 0 0 rg BT 152.88 653.25 Td (is ) Tj ET Q q 0 0 0 rg BT 162.13 653.25 Td (also ) Tj ET Q q 0 0 0 rg BT 180.82 653.25 Td (entitled ) Tj ET Q q 0 0 0 rg BT 213.38 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 223.74 653.25 Td (receive ) Tj ET Q q 0 0 0 rg BT 255.18 653.25 Td (an ) Tj ET Q q 0 0 0 rg BT 267.19 653.25 Td (additional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.76 653.25 Td ($120 ) Tj ET Q q 0 0 0 rg BT 332.34 653.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 361.23 653.25 Td ( ) Tj ET Q q 0 0 0 rg BT 363.81 653.25 Td (if ) Tj ET Q q 0 0 0 rg BT 372.49 653.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 402.27 653.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 445.94 653.25 Td (events ) Tj ET Q q 0 0 0 rg BT 474.07 653.25 Td (occur ) Tj ET Q q 0 0 0 rg BT 498.85 653.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.87 653.25 Td ($200 ) Tj ET Q q 0 0 0 rg BT 538.44 653.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.34 653.25 Td ( ) Tj ET Q q 0 0 0 rg BT 569.91 653.25 Td (if ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.02 641.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 88.27 641.25 Td (thresholds ) Tj ET Q q 0 0 0 rg BT 132.19 641.25 Td (are ) Tj ET Q q 0 0 0 rg BT 147.22 641.25 Td (achieved. ) Tj ET Q q 0 0 0 rg BT 187.86 641.25 Td (The ) Tj ET Q q 0 0 0 rg BT 206.22 641.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 250.68 641.25 Td (may ) Tj ET Q q 0 0 0 rg BT 270.71 641.25 Td (be ) Tj ET Q q 0 0 0 rg BT 282.96 641.25 Td (terminated ) Tj ET Q q 0 0 0 rg BT 328.54 641.25 Td (immediately ) Tj ET Q q 0 0 0 rg BT 381.34 641.25 Td (by ) Tj ET Q q 0 0 0 rg BT 394.15 641.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 418.09 641.25 Td (or ) Tj ET Q q 0 0 0 rg BT 429.23 641.25 Td (by ) Tj ET Q q 0 0 0 rg BT 442.05 641.25 Td (either ) Tj ET Q q 0 0 0 rg BT 467.63 641.25 Td (party ) Tj ET Q q 0 0 0 rg BT 490.99 641.25 Td (for ) Tj ET Q q 0 0 0 rg BT 505.46 641.25 Td (material ) Tj ET Q q 0 0 0 rg BT 541.04 641.25 Td (breaches ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (\(subsequent ) Tj ET Q q 0 0 0 rg BT 86.27 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 96.55 629.25 Td (a ) Tj ET Q q 0 0 0 rg BT 103.49 629.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 130.42 629.25 Td (period\). ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (Summarized financial information related to this alliance was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 568.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 568.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 568.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 568.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 568.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 568.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 568.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 542.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 542.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 542.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 542.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 542.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 542.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 542.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 516.75 348.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 516.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 516.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 516.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 516.75 60.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 516.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 515.50 516.75 60.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 581.75 m 447.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 581.75 m 451.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 581.75 m 511.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 581.75 m 515.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 581.75 m 575.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 581.75 m 447.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 568.75 m 447.5 568.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 581.75 m 451.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 581.75 m 511.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 568.75 m 511.5 568.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 581.75 m 515.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 581.75 m 575.5 581.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 515.5 568.75 m 575.5 568.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 586.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 436.70 585.98 Td (Y) Tj ET Q q 0 0 0 rg BT 442.03 585.98 Td (ear) Tj ET Q q 0 0 0 rg BT 452.62 585.98 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 513.35 585.98 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 573.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 409.00 572.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 473.00 572.98 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 537.00 572.98 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 559.48 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 88.73 559.48 Td (om ) Tj ET Q q 0 0 0 rg BT 104.19 559.48 Td (AbbV) Tj ET Q q 0 0 0 rg BT 129.30 559.48 Td (ie alliance:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 546.32 Td (Net product sales) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.00 546.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.65 546.32 Td (150) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 546.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 546.32 Td (132) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 546.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 546.32 Td (3) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 520.48 Td (Payments to/\(fr) Tj ET Q q 0 0 0 rg BT 104.19 520.48 Td (om\) ) Tj ET Q q 0 0 0 rg BT 122.79 520.48 Td (AbbV) Tj ET Q q 0 0 0 rg BT 147.99 520.48 Td (ie:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 507.32 Td (Cost of products sold – Profit sharing) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.00 507.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.65 507.32 Td (41) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 507.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 507.32 Td (34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.00 507.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 507.32 Td (1) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 478.68505859375 m 91.6591796875 478.68505859375 l s q 0 0 0 rg BT 36.00 480.25 Td (F-Star) Tj ET Q q 0 0 0 rg BT 63.59 480.25 Td ( ) Tj ET Q q 0 0 0 rg BT 65.54 480.25 Td (Alpha) Tj ET Q BT /F1 11.00 Tf ET q 0 0 0 rg BT 36.00 455.05 Td (I) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.66 455.05 Td (n ) Tj ET Q q 0 0 0 rg BT 46.72 455.05 Td (October ) Tj ET Q q 0 0 0 rg BT 80.98 455.05 Td (2014, ) Tj ET Q q 0 0 0 rg BT 105.53 455.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 128.71 455.05 Td (acquired ) Tj ET Q q 0 0 0 rg BT 165.18 455.05 Td (an ) Tj ET Q q 0 0 0 rg BT 176.67 455.05 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 216.49 455.05 Td (option ) Tj ET Q q 0 0 0 rg BT 244.10 455.05 Td (to ) Tj ET Q q 0 0 0 rg BT 253.93 455.05 Td (purchase ) Tj ET Q q 0 0 0 rg BT 291.52 455.05 Td (F-Star ) Tj ET Q q 0 0 0 rg BT 318.12 455.05 Td (Alpha ) Tj ET Q q 0 0 0 rg BT 344.62 455.05 Td (and ) Tj ET Q q 0 0 0 rg BT 361.11 455.05 Td (its ) Tj ET Q q 0 0 0 rg BT 372.61 455.05 Td (lead ) Tj ET Q q 0 0 0 rg BT 391.32 455.05 Td (asset ) Tj ET Q q 0 0 0 rg BT 412.81 455.05 Td (FS102, ) Tj ET Q q 0 0 0 rg BT 443.48 455.05 Td (an ) Tj ET Q q 0 0 0 rg BT 454.98 455.05 Td (anti-HER2 ) Tj ET Q q 0 0 0 rg BT 500.35 455.05 Td (antibody ) Tj ET Q q 0 0 0 rg BT 537.40 455.05 Td (fragment, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 443.05 Td (in ) Tj ET Q q 0 0 0 rg BT 45.92 443.05 Td (development ) Tj ET Q q 0 0 0 rg BT 99.71 443.05 Td (for ) Tj ET Q q 0 0 0 rg BT 113.52 443.05 Td (the ) Tj ET Q q 0 0 0 rg BT 127.88 443.05 Td (treatment ) Tj ET Q q 0 0 0 rg BT 167.78 443.05 Td (of ) Tj ET Q q 0 0 0 rg BT 178.25 443.05 Td (breast ) Tj ET Q q 0 0 0 rg BT 204.27 443.05 Td (and ) Tj ET Q q 0 0 0 rg BT 220.85 443.05 Td (gastric ) Tj ET Q q 0 0 0 rg BT 249.65 443.05 Td (cancer ) Tj ET Q q 0 0 0 rg BT 277.88 443.05 Td (among ) Tj ET Q q 0 0 0 rg BT 307.23 443.05 Td (a ) Tj ET Q q 0 0 0 rg BT 313.82 443.05 Td (well-defined ) Tj ET Q q 0 0 0 rg BT 366.49 443.05 Td (population ) Tj ET Q q 0 0 0 rg BT 411.41 443.05 Td (of ) Tj ET Q q 0 0 0 rg BT 421.88 443.05 Td (HER2-positive ) Tj ET Q q 0 0 0 rg BT 484.02 443.05 Td (patients. ) Tj ET Q q 0 0 0 rg BT 519.76 443.05 Td (In ) Tj ET Q q 0 0 0 rg BT 530.24 443.05 Td (2017, ) Tj ET Q q 0 0 0 rg BT 554.88 443.05 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 431.05 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 89.14 431.05 Td (development ) Tj ET Q q 0 0 0 rg BT 142.83 431.05 Td (of ) Tj ET Q q 0 0 0 rg BT 153.20 431.05 Td (FS102 ) Tj ET Q q 0 0 0 rg BT 181.36 431.05 Td (and ) Tj ET Q q 0 0 0 rg BT 197.83 431.05 Td (did ) Tj ET Q q 0 0 0 rg BT 212.65 431.05 Td (not ) Tj ET Q q 0 0 0 rg BT 227.47 431.05 Td (exercise ) Tj ET Q q 0 0 0 rg BT 262.26 431.05 Td (its ) Tj ET Q q 0 0 0 rg BT 273.74 431.05 Td (option, ) Tj ET Q q 0 0 0 rg BT 303.84 431.05 Td (resulting ) Tj ET Q q 0 0 0 rg BT 340.87 431.05 Td (in ) Tj ET Q q 0 0 0 rg BT 350.69 431.05 Td (an ) Tj ET Q q 0 0 0 rg BT 362.16 431.05 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 386.98 431.05 Td (char) Tj ET Q q 0 0 0 rg BT 404.01 431.05 Td (ge ) Tj ET Q q 0 0 0 rg BT 415.48 431.05 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.85 431.05 Td ($75 ) Tj ET Q q 0 0 0 rg BT 442.89 431.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.78 431.05 Td ( ) Tj ET Q q 0 0 0 rg BT 473.82 431.05 Td (included ) Tj ET Q q 0 0 0 rg BT 510.29 431.05 Td (in ) Tj ET Q q 0 0 0 rg BT 520.11 431.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 543.81 431.05 Td (expense ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 419.05 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 419.05 Td (attributed ) Tj ET Q q 0 0 0 rg BT 93.76 419.05 Td (to ) Tj ET Q q 0 0 0 rg BT 104.04 419.05 Td (noncontrolling ) Tj ET Q q 0 0 0 rg BT 165.42 419.05 Td (interest.) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 395.48505859375 m 81.82275390625 395.48505859375 l s q 0 0 0 rg BT 36.00 397.05 Td (Pr) Tj ET Q q 0 0 0 rg BT 46.37 397.05 Td (omedior) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 373.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.35 373.05 Td (September ) Tj ET Q q 0 0 0 rg BT 91.13 373.05 Td (2015, ) Tj ET Q q 0 0 0 rg BT 115.64 373.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 138.78 373.05 Td (purchased ) Tj ET Q q 0 0 0 rg BT 181.34 373.05 Td (a ) Tj ET Q q 0 0 0 rg BT 187.79 373.05 Td (warrant ) Tj ET Q q 0 0 0 rg BT 220.35 373.05 Td (that ) Tj ET Q q 0 0 0 rg BT 237.36 373.05 Td (gives ) Tj ET Q q 0 0 0 rg BT 260.48 373.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 283.62 373.05 Td (the ) Tj ET Q q 0 0 0 rg BT 297.86 373.05 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 337.64 373.05 Td (right ) Tj ET Q q 0 0 0 rg BT 358.54 373.05 Td (to ) Tj ET Q q 0 0 0 rg BT 368.33 373.05 Td (acquire ) Tj ET Q q 0 0 0 rg BT 399.77 373.05 Td (Promedior) Tj ET Q q 0 0 0 rg BT 441.59 373.05 Td (, ) Tj ET Q q 0 0 0 rg BT 446.11 373.05 Td (a ) Tj ET Q q 0 0 0 rg BT 452.56 373.05 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 511.79 373.05 Td (company ) Tj ET Q q 0 0 0 rg BT 550.46 373.05 Td (whose ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 361.05 Td (lead ) Tj ET Q q 0 0 0 rg BT 55.80 361.05 Td (asset, ) Tj ET Q q 0 0 0 rg BT 80.89 361.05 Td (PRM-151, ) Tj ET Q q 0 0 0 rg BT 125.99 361.05 Td (is ) Tj ET Q q 0 0 0 rg BT 135.80 361.05 Td (being ) Tj ET Q q 0 0 0 rg BT 161.17 361.05 Td (developed ) Tj ET Q q 0 0 0 rg BT 205.41 361.05 Td (for ) Tj ET Q q 0 0 0 rg BT 220.22 361.05 Td (the ) Tj ET Q q 0 0 0 rg BT 235.58 361.05 Td (treatment ) Tj ET Q q 0 0 0 rg BT 276.49 361.05 Td (of ) Tj ET Q q 0 0 0 rg BT 287.96 361.05 Td (IPF ) Tj ET Q q 0 0 0 rg BT 305.56 361.05 Td (and ) Tj ET Q q 0 0 0 rg BT 323.15 361.05 Td (MF) Tj ET Q q 0 0 0 rg BT 336.80 361.05 Td (. ) Tj ET Q q 0 0 0 rg BT 342.22 361.05 Td (The ) Tj ET Q q 0 0 0 rg BT 360.91 361.05 Td (warrant ) Tj ET Q q 0 0 0 rg BT 394.60 361.05 Td (is ) Tj ET Q q 0 0 0 rg BT 404.42 361.05 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 452.53 361.05 Td (upon ) Tj ET Q q 0 0 0 rg BT 475.68 361.05 Td (delivery ) Tj ET Q q 0 0 0 rg BT 511.59 361.05 Td (of ) Tj ET Q q 0 0 0 rg BT 523.07 361.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 549.54 361.05 Td (II ) Tj ET Q q 0 0 0 rg BT 559.35 361.05 Td (data ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.05 Td (following ) Tj ET Q q 0 0 0 rg BT 77.69 349.05 Td (either ) Tj ET Q q 0 0 0 rg BT 103.27 349.05 Td (of ) Tj ET Q q 0 0 0 rg BT 114.40 349.05 Td (the ) Tj ET Q q 0 0 0 rg BT 129.43 349.05 Td (IPF ) Tj ET Q q 0 0 0 rg BT 146.69 349.05 Td (or ) Tj ET Q q 0 0 0 rg BT 157.83 349.05 Td (MF ) Tj ET Q q 0 0 0 rg BT 175.09 349.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 201.22 349.05 Td (II ) Tj ET Q q 0 0 0 rg BT 210.69 349.05 Td (clinical ) Tj ET Q q 0 0 0 rg BT 242.93 349.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 273.51 349.05 Td (being ) Tj ET Q q 0 0 0 rg BT 298.54 349.05 Td (directed ) Tj ET Q q 0 0 0 rg BT 333.55 349.05 Td (by ) Tj ET Q q 0 0 0 rg BT 346.36 349.05 Td (Promedior) Tj ET Q q 0 0 0 rg BT 388.02 349.05 Td (. ) Tj ET Q q 0 0 0 rg BT 393.13 349.05 Td (The ) Tj ET Q q 0 0 0 rg BT 411.48 349.05 Td (upfront ) Tj ET Q q 0 0 0 rg BT 443.73 349.05 Td (payment ) Tj ET Q q 0 0 0 rg BT 480.97 349.05 Td (allocated ) Tj ET Q q 0 0 0 rg BT 519.86 349.05 Td (to ) Tj ET Q q 0 0 0 rg BT 530.45 349.05 Td (the ) Tj ET Q q 0 0 0 rg BT 545.47 349.05 Td (warrant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 337.05 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 53.99 337.05 Td ($84 ) Tj ET Q q 0 0 0 rg BT 71.42 337.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.31 337.05 Td ( ) Tj ET Q q 0 0 0 rg BT 102.75 337.05 Td (and ) Tj ET Q q 0 0 0 rg BT 119.62 337.05 Td (included ) Tj ET Q q 0 0 0 rg BT 156.49 337.05 Td (in ) Tj ET Q q 0 0 0 rg BT 166.70 337.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 190.80 337.05 Td (expenses ) Tj ET Q q 0 0 0 rg BT 229.33 337.05 Td (in ) Tj ET Q q 0 0 0 rg BT 239.55 337.05 Td (2015. ) Tj ET Q q 0 0 0 rg BT 264.31 337.05 Td (The ) Tj ET Q q 0 0 0 rg BT 282.29 337.05 Td (remaining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.26 337.05 Td ($66 ) Tj ET Q q 0 0 0 rg BT 342.70 337.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.59 337.05 Td ( ) Tj ET Q q 0 0 0 rg BT 374.02 337.05 Td (of ) Tj ET Q q 0 0 0 rg BT 384.79 337.05 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.44 337.05 Td ($150 ) Tj ET Q q 0 0 0 rg BT 421.87 337.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.76 337.05 Td ( ) Tj ET Q q 0 0 0 rg BT 453.20 337.05 Td (upfront ) Tj ET Q q 0 0 0 rg BT 485.07 337.05 Td (payment ) Tj ET Q q 0 0 0 rg BT 521.94 337.05 Td (was ) Tj ET Q q 0 0 0 rg BT 539.92 337.05 Td (allocated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.05 Td (to ) Tj ET Q q 0 0 0 rg BT 46.67 325.05 Td (Promedior) Tj ET Q q 0 0 0 rg BT 89.26 325.05 Td (’) Tj ET Q q 0 0 0 rg BT 92.04 325.05 Td (s ) Tj ET Q q 0 0 0 rg BT 98.83 325.05 Td (obligation ) Tj ET Q q 0 0 0 rg BT 142.27 325.05 Td (to ) Tj ET Q q 0 0 0 rg BT 152.95 325.05 Td (complete ) Tj ET Q q 0 0 0 rg BT 192.49 325.05 Td (the ) Tj ET Q q 0 0 0 rg BT 207.61 325.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 233.83 325.05 Td (II ) Tj ET Q q 0 0 0 rg BT 243.39 325.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 274.06 325.05 Td (which ) Tj ET Q q 0 0 0 rg BT 301.40 325.05 Td (was ) Tj ET Q q 0 0 0 rg BT 319.84 325.05 Td (amortized ) Tj ET Q q 0 0 0 rg BT 362.72 325.05 Td (over ) Tj ET Q q 0 0 0 rg BT 383.38 325.05 Td (the ) Tj ET Q q 0 0 0 rg BT 398.50 325.05 Td (expected ) Tj ET Q q 0 0 0 rg BT 436.92 325.05 Td (period ) Tj ET Q q 0 0 0 rg BT 465.37 325.05 Td (of ) Tj ET Q q 0 0 0 rg BT 476.59 325.05 Td (the ) Tj ET Q q 0 0 0 rg BT 491.70 325.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 517.93 325.05 Td (II ) Tj ET Q q 0 0 0 rg BT 527.48 325.05 Td (studies. ) Tj ET Q q 0 0 0 rg BT 560.45 325.05 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 313.05 Td (allocation ) Tj ET Q q 0 0 0 rg BT 76.81 313.05 Td (was ) Tj ET Q q 0 0 0 rg BT 93.74 313.05 Td (determined ) Tj ET Q q 0 0 0 rg BT 140.10 313.05 Td (using ) Tj ET Q q 0 0 0 rg BT 163.15 313.05 Td (Level ) Tj ET Q q 0 0 0 rg BT 187.30 313.05 Td (3 ) Tj ET Q q 0 0 0 rg BT 193.68 313.05 Td (inputs. ) Tj ET Q q 0 0 0 rg BT 222.01 313.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 244.51 313.05 Td (is ) Tj ET Q q 0 0 0 rg BT 252.56 313.05 Td (obligated ) Tj ET Q q 0 0 0 rg BT 291.16 313.05 Td (to ) Tj ET Q q 0 0 0 rg BT 300.32 313.05 Td (pay ) Tj ET Q q 0 0 0 rg BT 316.13 313.05 Td (an ) Tj ET Q q 0 0 0 rg BT 326.95 313.05 Td (additional ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 368.33 313.05 Td ($250 ) Tj ET Q q 0 0 0 rg BT 389.71 313.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.60 313.05 Td (, ) Tj ET Q q 0 0 0 rg BT 422.48 313.05 Td (plus ) Tj ET Q q 0 0 0 rg BT 440.53 313.05 Td (additional ) Tj ET Q q 0 0 0 rg BT 481.90 313.05 Td (aggregate ) Tj ET Q q 0 0 0 rg BT 522.14 313.05 Td (consideration ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 301.05 Td (of ) Tj ET Q q 0 0 0 rg BT 46.72 301.05 Td (up ) Tj ET Q q 0 0 0 rg BT 59.11 301.05 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 69.27 301.05 Td ($850 ) Tj ET Q q 0 0 0 rg BT 91.66 301.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 120.55 301.05 Td ( ) Tj ET Q q 0 0 0 rg BT 122.94 301.05 Td (for ) Tj ET Q q 0 0 0 rg BT 136.99 301.05 Td (contingent ) Tj ET Q q 0 0 0 rg BT 181.59 301.05 Td (development ) Tj ET Q q 0 0 0 rg BT 235.62 301.05 Td (and ) Tj ET Q q 0 0 0 rg BT 252.45 301.05 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 295.93 301.05 Td (approval ) Tj ET Q q 0 0 0 rg BT 333.30 301.05 Td (milestone ) Tj ET Q q 0 0 0 rg BT 374.57 301.05 Td (payments ) Tj ET Q q 0 0 0 rg BT 415.29 301.05 Td (in ) Tj ET Q q 0 0 0 rg BT 425.45 301.05 Td (the ) Tj ET Q q 0 0 0 rg BT 440.06 301.05 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 460.23 301.05 Td (and ) Tj ET Q q 0 0 0 rg BT 477.05 301.05 Td (Europe ) Tj ET Q q 0 0 0 rg BT 508.32 301.05 Td (if ) Tj ET Q q 0 0 0 rg BT 516.82 301.05 Td (it ) Tj ET Q q 0 0 0 rg BT 524.76 301.05 Td (exercises ) Tj ET Q q 0 0 0 rg BT 563.79 301.05 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 289.05 Td (warrant.) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 263.48505859374995 m 82.9189453125 263.48505859374995 l s q 0 0 0 rg BT 36.00 265.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 56.83 265.05 Td (Prime) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.24 241.05 Td (November ) Tj ET Q q 0 0 0 rg BT 90.35 241.05 Td (2015, ) Tj ET Q q 0 0 0 rg BT 114.76 241.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 137.79 241.05 Td (and ) Tj ET Q q 0 0 0 rg BT 154.13 241.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 173.82 241.05 Td (Prime ) Tj ET Q q 0 0 0 rg BT 199.61 241.05 Td (entered ) Tj ET Q q 0 0 0 rg BT 230.94 241.05 Td (into ) Tj ET Q q 0 0 0 rg BT 248.40 241.05 Td (an ) Tj ET Q q 0 0 0 rg BT 259.75 241.05 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 299.42 241.05 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 344.10 241.05 Td (licensing ) Tj ET Q q 0 0 0 rg BT 382.11 241.05 Td (and ) Tj ET Q q 0 0 0 rg BT 398.45 241.05 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 453.12 241.05 Td (agreement ) Tj ET Q q 0 0 0 rg BT 496.66 241.05 Td (for ) Tj ET Q q 0 0 0 rg BT 510.23 241.05 Td (the ) Tj ET Q q 0 0 0 rg BT 524.35 241.05 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 229.05 Td (and ) Tj ET Q q 0 0 0 rg BT 52.90 229.05 Td (commercialization ) Tj ET Q q 0 0 0 rg BT 129.77 229.05 Td (of ) Tj ET Q q 0 0 0 rg BT 140.56 229.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 160.80 229.05 Td (Prime’) Tj ET Q q 0 0 0 rg BT 187.46 229.05 Td (s ) Tj ET Q q 0 0 0 rg BT 193.81 229.05 Td (CSF1R ) Tj ET Q q 0 0 0 rg BT 225.74 229.05 Td (antibody ) Tj ET Q q 0 0 0 rg BT 263.19 229.05 Td (program, ) Tj ET Q q 0 0 0 rg BT 302.03 229.05 Td (including ) Tj ET Q q 0 0 0 rg BT 342.26 229.05 Td (cabiralizumab, ) Tj ET Q q 0 0 0 rg BT 403.86 229.05 Td (currently ) Tj ET Q q 0 0 0 rg BT 442.41 229.05 Td (in ) Tj ET Q q 0 0 0 rg BT 452.65 229.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 478.44 229.05 Td (I ) Tj ET Q q 0 0 0 rg BT 484.23 229.05 Td (and ) Tj ET Q q 0 0 0 rg BT 501.13 229.05 Td (II ) Tj ET Q q 0 0 0 rg BT 510.25 229.05 Td (development ) Tj ET Q q 0 0 0 rg BT 564.36 229.05 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.05 Td (IO ) Tj ET Q q 0 0 0 rg BT 47.81 217.05 Td (indications ) Tj ET Q q 0 0 0 rg BT 92.96 217.05 Td (and ) Tj ET Q q 0 0 0 rg BT 108.66 217.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 133.25 217.05 Td (II ) Tj ET Q q 0 0 0 rg BT 141.17 217.05 Td (development ) Tj ET Q q 0 0 0 rg BT 194.09 217.05 Td (for ) Tj ET Q q 0 0 0 rg BT 207.01 217.05 Td (PVNS. ) Tj ET Q q 0 0 0 rg BT 236.34 217.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 255.38 217.05 Td (Prime ) Tj ET Q q 0 0 0 rg BT 280.53 217.05 Td (is ) Tj ET Q q 0 0 0 rg BT 288.46 217.05 Td (responsible ) Tj ET Q q 0 0 0 rg BT 335.27 217.05 Td (for ) Tj ET Q q 0 0 0 rg BT 348.19 217.05 Td (the ) Tj ET Q q 0 0 0 rg BT 361.67 217.05 Td (completion ) Tj ET Q q 0 0 0 rg BT 407.92 217.05 Td (of ) Tj ET Q q 0 0 0 rg BT 417.51 217.05 Td (a ) Tj ET Q q 0 0 0 rg BT 423.21 217.05 Td (Phase ) Tj ET Q q 0 0 0 rg BT 447.81 217.05 Td (I ) Tj ET Q q 0 0 0 rg BT 452.40 217.05 Td (study ) Tj ET Q q 0 0 0 rg BT 475.33 217.05 Td (combining ) Tj ET Q q 0 0 0 rg BT 519.37 217.05 Td (cabiralizumab ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 205.05 Td (with ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 55.79 205.05 Td (Opdivo ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.25 205.05 Td (as ) Tj ET Q q 0 0 0 rg BT 97.60 205.05 Td (a ) Tj ET Q q 0 0 0 rg BT 104.05 205.05 Td (potential ) Tj ET Q q 0 0 0 rg BT 141.06 205.05 Td (treatment ) Tj ET Q q 0 0 0 rg BT 180.83 205.05 Td (for ) Tj ET Q q 0 0 0 rg BT 194.51 205.05 Td (a ) Tj ET Q q 0 0 0 rg BT 200.97 205.05 Td (variety ) Tj ET Q q 0 0 0 rg BT 230.75 205.05 Td (of ) Tj ET Q q 0 0 0 rg BT 241.09 205.05 Td (cancers. ) Tj ET Q q 0 0 0 rg BT 275.58 205.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 298.72 205.05 Td (is ) Tj ET Q q 0 0 0 rg BT 307.41 205.05 Td (responsible ) Tj ET Q q 0 0 0 rg BT 354.97 205.05 Td (for ) Tj ET Q q 0 0 0 rg BT 368.65 205.05 Td (development, ) Tj ET Q q 0 0 0 rg BT 424.82 205.05 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 485.15 205.05 Td (and ) Tj ET Q q 0 0 0 rg BT 501.60 205.05 Td (commercialization ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 193.05 Td (activities. ) Tj ET Q q 0 0 0 rg BT 76.81 193.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 96.81 193.05 Td (Prime ) Tj ET Q q 0 0 0 rg BT 122.91 193.05 Td (may ) Tj ET Q q 0 0 0 rg BT 142.34 193.05 Td (conduct ) Tj ET Q q 0 0 0 rg BT 176.21 193.05 Td (certain ) Tj ET Q q 0 0 0 rg BT 205.62 193.05 Td (studies ) Tj ET Q q 0 0 0 rg BT 235.62 193.05 Td (at ) Tj ET Q q 0 0 0 rg BT 245.05 193.05 Td (its ) Tj ET Q q 0 0 0 rg BT 256.71 193.05 Td (cost ) Tj ET Q q 0 0 0 rg BT 275.03 193.05 Td (to ) Tj ET Q q 0 0 0 rg BT 285.03 193.05 Td (develop ) Tj ET Q q 0 0 0 rg BT 318.90 193.05 Td (cabiralizumab ) Tj ET Q q 0 0 0 rg BT 377.75 193.05 Td (in ) Tj ET Q q 0 0 0 rg BT 387.74 193.05 Td (PVNS ) Tj ET Q q 0 0 0 rg BT 415.52 193.05 Td (and ) Tj ET Q q 0 0 0 rg BT 432.17 193.05 Td (in ) Tj ET Q q 0 0 0 rg BT 442.16 193.05 Td (combination ) Tj ET Q q 0 0 0 rg BT 494.37 193.05 Td (with ) Tj ET Q q 0 0 0 rg BT 514.36 193.05 Td (its ) Tj ET Q q 0 0 0 rg BT 526.02 193.05 Td (own ) Tj ET Q q 0 0 0 rg BT 545.46 193.05 Td (internal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.05 Td (oncology ) Tj ET Q q 0 0 0 rg BT 76.91 181.05 Td (pipeline ) Tj ET Q q 0 0 0 rg BT 112.81 181.05 Td (assets. ) Tj ET Q q 0 0 0 rg BT 142.33 181.05 Td (Five ) Tj ET Q q 0 0 0 rg BT 163.80 181.05 Td (Prime ) Tj ET Q q 0 0 0 rg BT 191.38 181.05 Td (also ) Tj ET Q q 0 0 0 rg BT 211.18 181.05 Td (retained ) Tj ET Q q 0 0 0 rg BT 247.07 181.05 Td (an ) Tj ET Q q 0 0 0 rg BT 260.20 181.05 Td (option ) Tj ET Q q 0 0 0 rg BT 289.45 181.05 Td (to ) Tj ET Q q 0 0 0 rg BT 300.92 181.05 Td (co-promote ) Tj ET Q q 0 0 0 rg BT 350.71 181.05 Td (in ) Tj ET Q q 0 0 0 rg BT 362.18 181.05 Td (the ) Tj ET Q q 0 0 0 rg BT 378.08 181.05 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 399.29 181.05 Td (The ) Tj ET Q q 0 0 0 rg BT 418.53 181.05 Td (agreement ) Tj ET Q q 0 0 0 rg BT 463.86 181.05 Td (replaces ) Tj ET Q q 0 0 0 rg BT 500.31 181.05 Td (a ) Tj ET Q q 0 0 0 rg BT 508.44 181.05 Td (previous ) Tj ET Q q 0 0 0 rg BT 546.57 181.05 Td (clinical ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 169.05 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 91.26 169.05 Td (agreement ) Tj ET Q q 0 0 0 rg BT 135.40 169.05 Td (between ) Tj ET Q q 0 0 0 rg BT 171.21 169.05 Td (the ) Tj ET Q q 0 0 0 rg BT 185.93 169.05 Td (two ) Tj ET Q q 0 0 0 rg BT 203.43 169.05 Td (parties.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 145.05 Td (In ) Tj ET Q q 0 0 0 rg BT 46.42 145.05 Td (consideration ) Tj ET Q q 0 0 0 rg BT 102.39 145.05 Td (for ) Tj ET Q q 0 0 0 rg BT 116.14 145.05 Td (licensing ) Tj ET Q q 0 0 0 rg BT 154.34 145.05 Td (rights, ) Tj ET Q q 0 0 0 rg BT 181.71 145.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 204.93 145.05 Td (made ) Tj ET Q q 0 0 0 rg BT 228.68 145.05 Td (an ) Tj ET Q q 0 0 0 rg BT 240.21 145.05 Td (upfront ) Tj ET Q q 0 0 0 rg BT 271.74 145.05 Td (payment ) Tj ET Q q 0 0 0 rg BT 308.27 145.05 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.69 145.05 Td ($350 ) Tj ET Q q 0 0 0 rg BT 340.79 145.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.68 145.05 Td ( ) Tj ET Q q 0 0 0 rg BT 371.77 145.05 Td (in ) Tj ET Q q 0 0 0 rg BT 381.65 145.05 Td (2015 ) Tj ET Q q 0 0 0 rg BT 403.74 145.05 Td (which ) Tj ET Q q 0 0 0 rg BT 430.27 145.05 Td (was ) Tj ET Q q 0 0 0 rg BT 447.92 145.05 Td (included ) Tj ET Q q 0 0 0 rg BT 484.44 145.05 Td (in ) Tj ET Q q 0 0 0 rg BT 494.32 145.05 Td (R&D ) Tj ET Q q 0 0 0 rg BT 518.08 145.05 Td (expense. ) Tj ET Q q 0 0 0 rg BT 554.88 145.05 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 133.05 Td (will ) Tj ET Q q 0 0 0 rg BT 54.19 133.05 Td (also ) Tj ET Q q 0 0 0 rg BT 72.94 133.05 Td (be ) Tj ET Q q 0 0 0 rg BT 85.02 133.05 Td (committed ) Tj ET Q q 0 0 0 rg BT 130.42 133.05 Td (to ) Tj ET Q q 0 0 0 rg BT 140.84 133.05 Td (pay ) Tj ET Q q 0 0 0 rg BT 157.92 133.05 Td (up ) Tj ET Q q 0 0 0 rg BT 170.56 133.05 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 180.97 133.05 Td ($1.4 ) Tj ET Q q 0 0 0 rg BT 201.11 133.05 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 227.22 133.05 Td ( ) Tj ET Q q 0 0 0 rg BT 229.86 133.05 Td (upon ) Tj ET Q q 0 0 0 rg BT 252.50 133.05 Td (the ) Tj ET Q q 0 0 0 rg BT 267.36 133.05 Td (achievement ) Tj ET Q q 0 0 0 rg BT 320.52 133.05 Td (of ) Tj ET Q q 0 0 0 rg BT 331.49 133.05 Td (contingent ) Tj ET Q q 0 0 0 rg BT 376.34 133.05 Td (development ) Tj ET Q q 0 0 0 rg BT 430.63 133.05 Td (and ) Tj ET Q q 0 0 0 rg BT 447.70 133.05 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 491.44 133.05 Td (milestones ) Tj ET Q q 0 0 0 rg BT 536.85 133.05 Td (as ) Tj ET Q q 0 0 0 rg BT 547.82 133.05 Td (well ) Tj ET Q q 0 0 0 rg BT 567.67 133.05 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 121.05 Td (future ) Tj ET Q q 0 0 0 rg BT 62.38 121.05 Td (royalties ) Tj ET Q q 0 0 0 rg BT 99.31 121.05 Td (if ) Tj ET Q q 0 0 0 rg BT 107.92 121.05 Td (the ) Tj ET Q q 0 0 0 rg BT 122.64 121.05 Td (product ) Tj ET Q q 0 0 0 rg BT 155.68 121.05 Td (is ) Tj ET Q q 0 0 0 rg BT 164.85 121.05 Td (approved ) Tj ET Q q 0 0 0 rg BT 204.56 121.05 Td (and ) Tj ET Q q 0 0 0 rg BT 221.50 121.05 Td (commercialized.) Tj ET Q endstream endobj 151 0 obj <> endobj 152 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (75) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 747.68505859375 m 67.0986328125 747.68505859375 l s q 0 0 0 rg BT 36.00 749.25 Td (Reckitt) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.53 725.25 Td (May ) Tj ET Q q 0 0 0 rg BT 67.06 725.25 Td (2013, ) Tj ET Q q 0 0 0 rg BT 91.77 725.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 115.09 725.25 Td (transferred ) Tj ET Q q 0 0 0 rg BT 160.60 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 170.58 725.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 201.66 725.25 Td (the ) Tj ET Q q 0 0 0 rg BT 216.08 725.25 Td (right ) Tj ET Q q 0 0 0 rg BT 237.17 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 247.15 725.25 Td (sell, ) Tj ET Q q 0 0 0 rg BT 265.74 725.25 Td (distribute ) Tj ET Q q 0 0 0 rg BT 305.72 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 322.36 725.25 Td (market ) Tj ET Q q 0 0 0 rg BT 352.32 725.25 Td (several ) Tj ET Q q 0 0 0 rg BT 382.84 725.25 Td (OTC ) Tj ET Q q 0 0 0 rg BT 405.04 725.25 Td (brands ) Tj ET Q q 0 0 0 rg BT 433.91 725.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 452.78 725.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 492.19 725.25 Td (in ) Tj ET Q q 0 0 0 rg BT 502.17 725.25 Td (Mexico ) Tj ET Q q 0 0 0 rg BT 534.92 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 551.56 725.25 Td (Brazil ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (through ) Tj ET Q q 0 0 0 rg BT 68.77 713.25 Td (May ) Tj ET Q q 0 0 0 rg BT 88.76 713.25 Td (2016. ) Tj ET Q q 0 0 0 rg BT 112.92 713.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 135.70 713.25 Td (received ) Tj ET Q q 0 0 0 rg BT 171.22 713.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 207.32 713.25 Td (on ) Tj ET Q q 0 0 0 rg BT 218.98 713.25 Td (net ) Tj ET Q q 0 0 0 rg BT 232.86 713.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 253.95 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 263.94 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 277.82 713.25 Td (products ) Tj ET Q q 0 0 0 rg BT 313.92 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 330.02 713.25 Td (exclusively ) Tj ET Q q 0 0 0 rg BT 377.22 713.25 Td (supplied ) Tj ET Q q 0 0 0 rg BT 412.77 713.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 441.63 713.25 Td (of ) Tj ET Q q 0 0 0 rg BT 451.62 713.25 Td (the ) Tj ET Q q 0 0 0 rg BT 465.50 713.25 Td (products ) Tj ET Q q 0 0 0 rg BT 501.60 713.25 Td (to ) Tj ET Q q 0 0 0 rg BT 511.03 713.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 541.58 713.25 Td (pursuant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (to ) Tj ET Q q 0 0 0 rg BT 46.47 701.25 Td (a ) Tj ET Q q 0 0 0 rg BT 53.61 701.25 Td (supply ) Tj ET Q q 0 0 0 rg BT 82.97 701.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 127.30 701.25 Td (at ) Tj ET Q q 0 0 0 rg BT 137.22 701.25 Td (cost ) Tj ET Q q 0 0 0 rg BT 156.02 701.25 Td (plus ) Tj ET Q q 0 0 0 rg BT 175.38 701.25 Td (a ) Tj ET Q q 0 0 0 rg BT 182.52 701.25 Td (markup. ) Tj ET Q q 0 0 0 rg BT 218.26 701.25 Td (Certain ) Tj ET Q q 0 0 0 rg BT 250.38 701.25 Td (limited ) Tj ET Q q 0 0 0 rg BT 281.41 701.25 Td (assets, ) Tj ET Q q 0 0 0 rg BT 309.93 701.25 Td (including ) Tj ET Q q 0 0 0 rg BT 350.40 701.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 393.64 701.25 Td (authorizations ) Tj ET Q q 0 0 0 rg BT 452.98 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 470.12 701.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 500.01 701.25 Td (employees ) Tj ET Q q 0 0 0 rg BT 545.47 701.25 Td (directly ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 76.37 689.25 Td (to ) Tj ET Q q 0 0 0 rg BT 86.21 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 100.48 689.25 Td (business, ) Tj ET Q q 0 0 0 rg BT 138.92 689.25 Td (were ) Tj ET Q q 0 0 0 rg BT 160.40 689.25 Td (transferred ) Tj ET Q q 0 0 0 rg BT 205.76 689.25 Td (to ) Tj ET Q q 0 0 0 rg BT 215.59 689.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 246.53 689.25 Td (at ) Tj ET Q q 0 0 0 rg BT 255.80 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 270.07 689.25 Td (start ) Tj ET Q q 0 0 0 rg BT 289.34 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 299.72 689.25 Td (the ) Tj ET Q q 0 0 0 rg BT 313.99 689.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 347.13 689.25 Td (period. ) Tj ET Q q 0 0 0 rg BT 377.23 689.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 400.41 689.25 Td (retained ) Tj ET Q q 0 0 0 rg BT 434.66 689.25 Td (ownership ) Tj ET Q q 0 0 0 rg BT 478.38 689.25 Td (of ) Tj ET Q q 0 0 0 rg BT 488.76 689.25 Td (all ) Tj ET Q q 0 0 0 rg BT 500.81 689.25 Td (other ) Tj ET Q q 0 0 0 rg BT 523.41 689.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 548.79 689.25 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (to ) Tj ET Q q 0 0 0 rg BT 46.28 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 61.00 677.25 Td (business ) Tj ET Q q 0 0 0 rg BT 97.39 677.25 Td (including ) Tj ET Q q 0 0 0 rg BT 137.66 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 152.38 677.25 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 199.30 677.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 236.79 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 251.50 677.25 Td (products.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.84 653.25 Td (also ) Tj ET Q q 0 0 0 rg BT 78.66 653.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 111.37 653.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 142.96 653.25 Td (an ) Tj ET Q q 0 0 0 rg BT 155.12 653.25 Td (option ) Tj ET Q q 0 0 0 rg BT 183.39 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 193.89 653.25 Td (acquire ) Tj ET Q q 0 0 0 rg BT 226.03 653.25 Td (the ) Tj ET Q q 0 0 0 rg BT 240.96 653.25 Td (trademarks, ) Tj ET Q q 0 0 0 rg BT 290.60 653.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 331.64 653.25 Td (and ) Tj ET Q q 0 0 0 rg BT 348.80 653.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 378.71 653.25 Td (other ) Tj ET Q q 0 0 0 rg BT 401.98 653.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 428.02 653.25 Td (exclusively ) Tj ET Q q 0 0 0 rg BT 476.28 653.25 Td (related ) Tj ET Q q 0 0 0 rg BT 506.20 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 516.70 653.25 Td (the ) Tj ET Q q 0 0 0 rg BT 531.63 653.25 Td (products ) Tj ET Q q 0 0 0 rg BT 568.78 653.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.53 641.25 Td (end ) Tj ET Q q 0 0 0 rg BT 67.27 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 77.91 641.25 Td (the ) Tj ET Q q 0 0 0 rg BT 92.44 641.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 125.83 641.25 Td (period ) Tj ET Q q 0 0 0 rg BT 153.69 641.25 Td (at ) Tj ET Q q 0 0 0 rg BT 163.21 641.25 Td (a ) Tj ET Q q 0 0 0 rg BT 169.96 641.25 Td (price ) Tj ET Q q 0 0 0 rg BT 192.26 641.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 239.54 641.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 279.07 641.25 Td (based ) Tj ET Q q 0 0 0 rg BT 304.14 641.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 326.45 641.25 Td (a ) Tj ET Q q 0 0 0 rg BT 333.20 641.25 Td (multiple ) Tj ET Q q 0 0 0 rg BT 368.84 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 379.48 641.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 401.22 641.25 Td (from ) Tj ET Q q 0 0 0 rg BT 422.97 641.25 Td (May ) Tj ET Q q 0 0 0 rg BT 443.61 641.25 Td (2014 ) Tj ET Q q 0 0 0 rg BT 465.92 641.25 Td (through ) Tj ET Q q 0 0 0 rg BT 499.33 641.25 Td (May ) Tj ET Q q 0 0 0 rg BT 519.97 641.25 Td (2016. ) Tj ET Q q 0 0 0 rg BT 544.78 641.25 Td (In ) Tj ET Q q 0 0 0 rg BT 554.91 641.25 Td (April ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (2014, ) Tj ET Q q 0 0 0 rg BT 61.13 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 75.98 629.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 109.70 629.25 Td (was ) Tj ET Q q 0 0 0 rg BT 127.88 629.25 Td (modified ) Tj ET Q q 0 0 0 rg BT 166.62 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 177.03 629.25 Td (provide ) Tj ET Q q 0 0 0 rg BT 210.21 629.25 Td (an ) Tj ET Q q 0 0 0 rg BT 222.28 629.25 Td (option ) Tj ET Q q 0 0 0 rg BT 250.47 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 260.88 629.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 292.39 629.25 Td (to ) Tj ET Q q 0 0 0 rg BT 302.80 629.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 340.97 629.25 Td (a ) Tj ET Q q 0 0 0 rg BT 348.04 629.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 371.80 629.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 432.74 629.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 463.69 629.25 Td (located ) Tj ET Q q 0 0 0 rg BT 495.19 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 505.60 629.25 Td (Mexico ) Tj ET Q q 0 0 0 rg BT 538.78 629.25 Td (primarily ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (dedicated ) Tj ET Q q 0 0 0 rg BT 75.94 617.25 Td (to ) Tj ET Q q 0 0 0 rg BT 85.34 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 99.18 617.25 Td (products ) Tj ET Q q 0 0 0 rg BT 135.24 617.25 Td (included ) Tj ET Q q 0 0 0 rg BT 171.30 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 180.71 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 194.55 617.25 Td (alliance ) Tj ET Q q 0 0 0 rg BT 227.26 617.25 Td (as ) Tj ET Q q 0 0 0 rg BT 237.22 617.25 Td (well ) Tj ET Q q 0 0 0 rg BT 256.06 617.25 Td (as ) Tj ET Q q 0 0 0 rg BT 266.01 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 279.86 617.25 Td (related ) Tj ET Q q 0 0 0 rg BT 308.68 617.25 Td (employees. ) Tj ET Q q 0 0 0 rg BT 355.57 617.25 Td (In ) Tj ET Q q 0 0 0 rg BT 365.53 617.25 Td (July ) Tj ET Q q 0 0 0 rg BT 383.82 617.25 Td (2015, ) Tj ET Q q 0 0 0 rg BT 407.95 617.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 438.45 617.25 Td (notified ) Tj ET Q q 0 0 0 rg BT 471.18 617.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 493.93 617.25 Td (that ) Tj ET Q q 0 0 0 rg BT 510.55 617.25 Td (it ) Tj ET Q q 0 0 0 rg BT 517.73 617.25 Td (was ) Tj ET Q q 0 0 0 rg BT 534.91 617.25 Td (exercising ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (its ) Tj ET Q q 0 0 0 rg BT 47.95 605.25 Td (option. ) Tj ET Q q 0 0 0 rg BT 78.50 605.25 Td (In ) Tj ET Q q 0 0 0 rg BT 89.33 605.25 Td (May ) Tj ET Q q 0 0 0 rg BT 110.17 605.25 Td (2016, ) Tj ET Q q 0 0 0 rg BT 135.17 605.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 158.79 605.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 177.96 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 192.67 605.25 Td (business ) Tj ET Q q 0 0 0 rg BT 229.07 605.25 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 243.23 605.25 Td ($317 ) Tj ET Q q 0 0 0 rg BT 265.73 605.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 294.62 605.25 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 583.65 Td (Non-refundable ) Tj ET Q q 0 0 0 rg BT 102.43 583.65 Td (upfront ) Tj ET Q q 0 0 0 rg BT 134.99 583.65 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 173.65 583.65 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 185.10 583.65 Td ($485 ) Tj ET Q q 0 0 0 rg BT 208.22 583.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 237.11 583.65 Td ( ) Tj ET Q q 0 0 0 rg BT 240.23 583.65 Td (received ) Tj ET Q q 0 0 0 rg BT 277.22 583.65 Td (by ) Tj ET Q q 0 0 0 rg BT 290.34 583.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 314.58 583.65 Td (in ) Tj ET Q q 0 0 0 rg BT 325.48 583.65 Td (2013 ) Tj ET Q q 0 0 0 rg BT 348.60 583.65 Td (were ) Tj ET Q q 0 0 0 rg BT 371.15 583.65 Td (allocated ) Tj ET Q q 0 0 0 rg BT 410.36 583.65 Td (to ) Tj ET Q q 0 0 0 rg BT 421.26 583.65 Td (two ) Tj ET Q q 0 0 0 rg BT 439.39 583.65 Td (units ) Tj ET Q q 0 0 0 rg BT 461.96 583.65 Td (of ) Tj ET Q q 0 0 0 rg BT 473.41 583.65 Td (accounting, ) Tj ET Q q 0 0 0 rg BT 522.90 583.65 Td (including ) Tj ET Q q 0 0 0 rg BT 563.80 583.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 571.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 61.35 571.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 107.22 571.65 Td (to ) Tj ET Q q 0 0 0 rg BT 117.56 571.65 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 149.01 571.65 Td (and ) Tj ET Q q 0 0 0 rg BT 166.02 571.65 Td (the ) Tj ET Q q 0 0 0 rg BT 180.80 571.65 Td (fair ) Tj ET Q q 0 0 0 rg BT 197.25 571.65 Td (value ) Tj ET Q q 0 0 0 rg BT 221.47 571.65 Td (of ) Tj ET Q q 0 0 0 rg BT 232.37 571.65 Td (the ) Tj ET Q q 0 0 0 rg BT 247.15 571.65 Td (option ) Tj ET Q q 0 0 0 rg BT 275.28 571.65 Td (to ) Tj ET Q q 0 0 0 rg BT 285.62 571.65 Td (purchase ) Tj ET Q q 0 0 0 rg BT 323.73 571.65 Td (the ) Tj ET Q q 0 0 0 rg BT 338.51 571.65 Td (remaining ) Tj ET Q q 0 0 0 rg BT 381.62 571.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 407.52 571.65 Td (using ) Tj ET Q q 0 0 0 rg BT 431.75 571.65 Td (the ) Tj ET Q q 0 0 0 rg BT 446.54 571.65 Td (best ) Tj ET Q q 0 0 0 rg BT 465.21 571.65 Td (estimate ) Tj ET Q q 0 0 0 rg BT 501.10 571.65 Td (of ) Tj ET Q q 0 0 0 rg BT 512.00 571.65 Td (the ) Tj ET Q q 0 0 0 rg BT 526.78 571.65 Td (selling ) Tj ET Q q 0 0 0 rg BT 556.02 571.65 Td (price ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 559.65 Td (for ) Tj ET Q q 0 0 0 rg BT 49.86 559.65 Td (these ) Tj ET Q q 0 0 0 rg BT 72.61 559.65 Td (elements ) Tj ET Q q 0 0 0 rg BT 110.35 559.65 Td (after ) Tj ET Q q 0 0 0 rg BT 130.86 559.65 Td (considering ) Tj ET Q q 0 0 0 rg BT 179.72 559.65 Td (various ) Tj ET Q q 0 0 0 rg BT 211.36 559.65 Td (market ) Tj ET Q q 0 0 0 rg BT 241.32 559.65 Td (factors. ) Tj ET Q q 0 0 0 rg BT 273.07 559.65 Td (These ) Tj ET Q q 0 0 0 rg BT 299.14 559.65 Td (market ) Tj ET Q q 0 0 0 rg BT 329.11 559.65 Td (factors ) Tj ET Q q 0 0 0 rg BT 358.51 559.65 Td (included ) Tj ET Q q 0 0 0 rg BT 395.15 559.65 Td (an ) Tj ET Q q 0 0 0 rg BT 406.79 559.65 Td (analysis ) Tj ET Q q 0 0 0 rg BT 441.20 559.65 Td (of ) Tj ET Q q 0 0 0 rg BT 451.73 559.65 Td (any ) Tj ET Q q 0 0 0 rg BT 468.37 559.65 Td (estimated ) Tj ET Q q 0 0 0 rg BT 508.89 559.65 Td (excess ) Tj ET Q q 0 0 0 rg BT 537.19 559.65 Td (of ) Tj ET Q q 0 0 0 rg BT 547.72 559.65 Td (the ) Tj ET Q q 0 0 0 rg BT 562.13 559.65 Td (fair ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 547.65 Td (value ) Tj ET Q q 0 0 0 rg BT 59.86 547.65 Td (of ) Tj ET Q q 0 0 0 rg BT 70.39 547.65 Td (the ) Tj ET Q q 0 0 0 rg BT 84.81 547.65 Td (business ) Tj ET Q q 0 0 0 rg BT 120.90 547.65 Td (over ) Tj ET Q q 0 0 0 rg BT 140.87 547.65 Td (the ) Tj ET Q q 0 0 0 rg BT 155.29 547.65 Td (potential ) Tj ET Q q 0 0 0 rg BT 192.48 547.65 Td (purchase ) Tj ET Q q 0 0 0 rg BT 230.22 547.65 Td (price ) Tj ET Q q 0 0 0 rg BT 252.40 547.65 Td (if ) Tj ET Q q 0 0 0 rg BT 260.71 547.65 Td (the ) Tj ET Q q 0 0 0 rg BT 275.13 547.65 Td (option ) Tj ET Q q 0 0 0 rg BT 302.89 547.65 Td (is ) Tj ET Q q 0 0 0 rg BT 311.76 547.65 Td (exercised. ) Tj ET Q q 0 0 0 rg BT 354.05 547.65 Td (The ) Tj ET Q q 0 0 0 rg BT 371.80 547.65 Td (fair ) Tj ET Q q 0 0 0 rg BT 387.88 547.65 Td (value ) Tj ET Q q 0 0 0 rg BT 411.74 547.65 Td (of ) Tj ET Q q 0 0 0 rg BT 422.27 547.65 Td (the ) Tj ET Q q 0 0 0 rg BT 436.69 547.65 Td (option ) Tj ET Q q 0 0 0 rg BT 464.44 547.65 Td (was ) Tj ET Q q 0 0 0 rg BT 482.20 547.65 Td (determined ) Tj ET Q q 0 0 0 rg BT 529.38 547.65 Td (using ) Tj ET Q q 0 0 0 rg BT 553.25 547.65 Td (Level ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 535.65 Td (3 ) Tj ET Q q 0 0 0 rg BT 43.73 535.65 Td (inputs ) Tj ET Q q 0 0 0 rg BT 70.92 535.65 Td (and ) Tj ET Q q 0 0 0 rg BT 88.09 535.65 Td (included ) Tj ET Q q 0 0 0 rg BT 125.25 535.65 Td (in ) Tj ET Q q 0 0 0 rg BT 135.77 535.65 Td (other ) Tj ET Q q 0 0 0 rg BT 159.05 535.65 Td (liabilities. ) Tj ET Q q 0 0 0 rg BT 201.50 535.65 Td (During ) Tj ET Q q 0 0 0 rg BT 232.56 535.65 Td (2015, ) Tj ET Q q 0 0 0 rg BT 257.79 535.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 281.65 535.65 Td (recognized ) Tj ET Q q 0 0 0 rg BT 328.25 535.65 Td (other ) Tj ET Q q 0 0 0 rg BT 351.53 535.65 Td (income ) Tj ET Q q 0 0 0 rg BT 383.69 535.65 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.76 535.65 Td ($123 ) Tj ET Q q 0 0 0 rg BT 417.49 535.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.38 535.65 Td ( ) Tj ET Q q 0 0 0 rg BT 449.11 535.65 Td (to ) Tj ET Q q 0 0 0 rg BT 459.63 535.65 Td (decrease ) Tj ET Q q 0 0 0 rg BT 496.77 535.65 Td (the ) Tj ET Q q 0 0 0 rg BT 511.72 535.65 Td (fair ) Tj ET Q q 0 0 0 rg BT 528.33 535.65 Td (value ) Tj ET Q q 0 0 0 rg BT 552.72 535.65 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 535.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 523.65 Td (option ) Tj ET Q q 0 0 0 rg BT 63.53 523.65 Td (to ) Tj ET Q q 0 0 0 rg BT 73.28 523.65 Td (zero ) Tj ET Q q 0 0 0 rg BT 92.46 523.65 Td (due ) Tj ET Q q 0 0 0 rg BT 108.87 523.65 Td (to ) Tj ET Q q 0 0 0 rg BT 118.62 523.65 Td (the ) Tj ET Q q 0 0 0 rg BT 132.81 523.65 Td (strengthening ) Tj ET Q q 0 0 0 rg BT 189.21 523.65 Td (of ) Tj ET Q q 0 0 0 rg BT 199.51 523.65 Td (the ) Tj ET Q q 0 0 0 rg BT 213.70 523.65 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 233.46 523.65 Td (dollar ) Tj ET Q q 0 0 0 rg BT 258.75 523.65 Td (against ) Tj ET Q q 0 0 0 rg BT 289.05 523.65 Td (local ) Tj ET Q q 0 0 0 rg BT 310.46 523.65 Td (currencies. ) Tj ET Q q 0 0 0 rg BT 355.87 523.65 Td (The ) Tj ET Q q 0 0 0 rg BT 373.39 523.65 Td (amount ) Tj ET Q q 0 0 0 rg BT 405.35 523.65 Td (allocated ) Tj ET Q q 0 0 0 rg BT 443.41 523.65 Td (to ) Tj ET Q q 0 0 0 rg BT 453.16 523.65 Td (the ) Tj ET Q q 0 0 0 rg BT 467.35 523.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 492.10 523.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 537.38 523.65 Td (to ) Tj ET Q q 0 0 0 rg BT 547.13 523.65 Td (Reckitt ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 511.65 Td (is ) Tj ET Q q 0 0 0 rg BT 45.17 511.65 Td (amortized ) Tj ET Q q 0 0 0 rg BT 87.65 511.65 Td (as ) Tj ET Q q 0 0 0 rg BT 98.48 511.65 Td (alliance ) Tj ET Q q 0 0 0 rg BT 132.07 511.65 Td (revenue ) Tj ET Q q 0 0 0 rg BT 166.21 511.65 Td (over ) Tj ET Q q 0 0 0 rg BT 186.48 511.65 Td (the ) Tj ET Q q 0 0 0 rg BT 201.20 511.65 Td (contractual ) Tj ET Q q 0 0 0 rg BT 248.12 511.65 Td (term. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 487.65 Td (Summarized ) Tj ET Q q 0 0 0 rg BT 89.04 487.65 Td (financial ) Tj ET Q q 0 0 0 rg BT 126.52 487.65 Td (information ) Tj ET Q q 0 0 0 rg BT 176.23 487.65 Td (related ) Tj ET Q q 0 0 0 rg BT 205.94 487.65 Td (to ) Tj ET Q q 0 0 0 rg BT 216.21 487.65 Td (this ) Tj ET Q q 0 0 0 rg BT 233.16 487.65 Td (alliance ) Tj ET Q q 0 0 0 rg BT 266.75 487.65 Td (was ) Tj ET Q q 0 0 0 rg BT 284.80 487.65 Td (as ) Tj ET Q q 0 0 0 rg BT 295.63 487.65 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 453.15 412.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 453.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 453.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 453.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 453.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 425.15 412.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 425.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 425.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 425.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 425.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 397.15 412.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 397.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 397.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 397.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 397.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 369.15 412.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 369.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 369.15 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 369.15 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 369.15 60.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 465.15 m 512.5 465.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 465.15 m 516.5 465.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 465.15 m 576.5 465.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 465.15 m 512.5 465.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 453.15 m 512.5 453.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 465.15 m 576.5 465.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 453.15 m 576.5 453.15 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 453.15 m 512.5 453.15 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 469.10 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 469.70 469.23 Td (Y) Tj ET Q q 0 0 0 rg BT 474.59 469.23 Td (ear) Tj ET Q q 0 0 0 rg BT 485.55 469.23 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 546.28 469.23 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 457.10 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 457.23 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 457.23 Td (2015) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 443.88 Td (Revenues fr) Tj ET Q q 0 0 0 rg BT 89.73 443.88 Td (om Reckitt alliance:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 429.72 Td (Alliance revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 429.72 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 429.72 Td (48) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 429.72 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 429.72 Td (140) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 401.72 Td (Other income \(net\) – Divestiture gain) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.30 401.77 Td (\(277) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.65 401.72 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 401.72 Td (—) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 373.88 Td (Selected ) Tj ET Q q 0 0 0 rg BT 75.93 373.88 Td (Alliance Cash Flow Information:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 359.72 Td (Other changes in operating assets and liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 359.72 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 359.72 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 359.72 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 359.72 Td (\(129) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 359.72 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 345.72 Td (Divestiture and other proceeds) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 345.72 Td (317) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 345.72 Td (—) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 316.08505859375 m 142.669921875 316.08505859375 l s q 0 0 0 rg BT 36.00 317.65 Td (The Medicines Company) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.65 Td (In ) Tj ET Q q 0 0 0 rg BT 46.72 293.65 Td (February ) Tj ET Q q 0 0 0 rg BT 85.20 293.65 Td (2013, ) Tj ET Q q 0 0 0 rg BT 110.09 293.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 133.60 293.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 179.29 293.65 Td (to ) Tj ET Q q 0 0 0 rg BT 189.28 293.65 Td (The ) Tj ET Q q 0 0 0 rg BT 207.22 293.65 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 251.26 293.65 Td (Company ) Tj ET Q q 0 0 0 rg BT 292.53 293.65 Td (the ) Tj ET Q q 0 0 0 rg BT 307.14 293.65 Td (right ) Tj ET Q q 0 0 0 rg BT 328.41 293.65 Td (to ) Tj ET Q q 0 0 0 rg BT 338.57 293.65 Td (sell, ) Tj ET Q q 0 0 0 rg BT 357.35 293.65 Td (distribute ) Tj ET Q q 0 0 0 rg BT 397.51 293.65 Td (and ) Tj ET Q q 0 0 0 rg BT 414.33 293.65 Td (market ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 444.48 293.65 Td (Recothr) Tj ET Q q 0 0 0 rg BT 475.77 293.65 Td (om*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.99 293.65 Td ( ) Tj ET Q q 0 0 0 rg BT 495.38 293.65 Td (on ) Tj ET Q q 0 0 0 rg BT 507.76 293.65 Td (a ) Tj ET Q q 0 0 0 rg BT 514.59 293.65 Td (global ) Tj ET Q q 0 0 0 rg BT 541.97 293.65 Td (basis ) Tj ET Q q 0 0 0 rg BT 564.36 293.65 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.65 Td (two ) Tj ET Q q 0 0 0 rg BT 53.93 281.65 Td (years. ) Tj ET Q q 0 0 0 rg BT 80.46 281.65 Td (Certain ) Tj ET Q q 0 0 0 rg BT 112.82 281.65 Td (employees ) Tj ET Q q 0 0 0 rg BT 158.51 281.65 Td (directly ) Tj ET Q q 0 0 0 rg BT 191.99 281.65 Td (attributed ) Tj ET Q q 0 0 0 rg BT 233.24 281.65 Td (to ) Tj ET Q q 0 0 0 rg BT 243.94 281.65 Td (the ) Tj ET Q q 0 0 0 rg BT 259.09 281.65 Td (business ) Tj ET Q q 0 0 0 rg BT 295.91 281.65 Td (and ) Tj ET Q q 0 0 0 rg BT 313.28 281.65 Td (certain ) Tj ET Q q 0 0 0 rg BT 343.41 281.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 369.67 281.65 Td (were ) Tj ET Q q 0 0 0 rg BT 392.03 281.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 438.27 281.65 Td (to ) Tj ET Q q 0 0 0 rg BT 448.76 281.65 Td (The ) Tj ET Q q 0 0 0 rg BT 467.24 281.65 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 511.82 281.65 Td (Company ) Tj ET Q q 0 0 0 rg BT 553.64 281.65 Td (at ) Tj ET Q q 0 0 0 rg BT 563.79 281.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.65 Td (start ) Tj ET Q q 0 0 0 rg BT 55.00 269.65 Td (of ) Tj ET Q q 0 0 0 rg BT 65.12 269.65 Td (the ) Tj ET Q q 0 0 0 rg BT 79.12 269.65 Td (alliance ) Tj ET Q q 0 0 0 rg BT 111.99 269.65 Td (period, ) Tj ET Q q 0 0 0 rg BT 141.82 269.65 Td (including ) Tj ET Q q 0 0 0 rg BT 181.38 269.65 Td (the ) Tj ET Q q 0 0 0 rg BT 195.38 269.65 Td (Biologics ) Tj ET Q q 0 0 0 rg BT 235.50 269.65 Td (License ) Tj ET Q q 0 0 0 rg BT 267.99 269.65 Td (Application ) Tj ET Q q 0 0 0 rg BT 316.98 269.65 Td (and ) Tj ET Q q 0 0 0 rg BT 333.21 269.65 Td (related ) Tj ET Q q 0 0 0 rg BT 362.19 269.65 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 405.07 269.65 Td (assets. ) Tj ET Q q 0 0 0 rg BT 432.69 269.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 455.59 269.65 Td (retained ) Tj ET Q q 0 0 0 rg BT 489.58 269.65 Td (all ) Tj ET Q q 0 0 0 rg BT 501.36 269.65 Td (other ) Tj ET Q q 0 0 0 rg BT 523.69 269.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 548.81 269.65 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.65 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 46.28 257.65 Td (Recothr) Tj ET Q q 0 0 0 rg BT 77.56 257.65 Td (om*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 94.78 257.65 Td ( ) Tj ET Q q 0 0 0 rg BT 97.28 257.65 Td (including ) Tj ET Q q 0 0 0 rg BT 137.56 257.65 Td (the ) Tj ET Q q 0 0 0 rg BT 152.27 257.65 Td (patents, ) Tj ET Q q 0 0 0 rg BT 185.60 257.65 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 232.52 257.65 Td (and ) Tj ET Q q 0 0 0 rg BT 249.46 257.65 Td (inventory) Tj ET Q q 0 0 0 rg BT 287.14 257.65 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.64 233.65 Td (also ) Tj ET Q q 0 0 0 rg BT 78.27 233.65 Td (granted ) Tj ET Q q 0 0 0 rg BT 110.59 233.65 Td (The ) Tj ET Q q 0 0 0 rg BT 128.66 233.65 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 172.83 233.65 Td (Company ) Tj ET Q q 0 0 0 rg BT 214.23 233.65 Td (an ) Tj ET Q q 0 0 0 rg BT 226.19 233.65 Td (option ) Tj ET Q q 0 0 0 rg BT 254.27 233.65 Td (to ) Tj ET Q q 0 0 0 rg BT 264.56 233.65 Td (acquire ) Tj ET Q q 0 0 0 rg BT 296.51 233.65 Td (the ) Tj ET Q q 0 0 0 rg BT 311.24 233.65 Td (patents, ) Tj ET Q q 0 0 0 rg BT 344.59 233.65 Td (trademarks, ) Tj ET Q q 0 0 0 rg BT 394.03 233.65 Td (inventory ) Tj ET Q q 0 0 0 rg BT 434.87 233.65 Td (and ) Tj ET Q q 0 0 0 rg BT 451.83 233.65 Td (certain ) Tj ET Q q 0 0 0 rg BT 481.55 233.65 Td (other ) Tj ET Q q 0 0 0 rg BT 504.61 233.65 Td (assets ) Tj ET Q q 0 0 0 rg BT 530.46 233.65 Td (exclusively ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.65 Td (related ) Tj ET Q q 0 0 0 rg BT 65.75 221.65 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 76.07 221.65 Td (Recothr) Tj ET Q q 0 0 0 rg BT 107.36 221.65 Td (om*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 124.58 221.65 Td ( ) Tj ET Q q 0 0 0 rg BT 127.12 221.65 Td (at ) Tj ET Q q 0 0 0 rg BT 136.88 221.65 Td (a ) Tj ET Q q 0 0 0 rg BT 143.87 221.65 Td (price ) Tj ET Q q 0 0 0 rg BT 166.40 221.65 Td (determined ) Tj ET Q q 0 0 0 rg BT 213.93 221.65 Td (based ) Tj ET Q q 0 0 0 rg BT 239.24 221.65 Td (on ) Tj ET Q q 0 0 0 rg BT 251.78 221.65 Td (a ) Tj ET Q q 0 0 0 rg BT 258.77 221.65 Td (multiple ) Tj ET Q q 0 0 0 rg BT 294.64 221.65 Td (of ) Tj ET Q q 0 0 0 rg BT 305.52 221.65 Td (sales ) Tj ET Q q 0 0 0 rg BT 327.50 221.65 Td (\(plus ) Tj ET Q q 0 0 0 rg BT 350.05 221.65 Td (the ) Tj ET Q q 0 0 0 rg BT 364.81 221.65 Td (cost ) Tj ET Q q 0 0 0 rg BT 383.46 221.65 Td (of ) Tj ET Q q 0 0 0 rg BT 394.34 221.65 Td (any ) Tj ET Q q 0 0 0 rg BT 411.32 221.65 Td (remaining ) Tj ET Q q 0 0 0 rg BT 454.41 221.65 Td (inventory ) Tj ET Q q 0 0 0 rg BT 495.28 221.65 Td (held ) Tj ET Q q 0 0 0 rg BT 515.04 221.65 Td (by ) Tj ET Q q 0 0 0 rg BT 527.59 221.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 551.26 221.65 Td (at ) Tj ET Q q 0 0 0 rg BT 561.02 221.65 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.65 Td (time\). ) Tj ET Q q 0 0 0 rg BT 62.54 209.65 Td (The ) Tj ET Q q 0 0 0 rg BT 81.26 209.65 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 126.09 209.65 Td (Company ) Tj ET Q q 0 0 0 rg BT 168.14 209.65 Td (exercised ) Tj ET Q q 0 0 0 rg BT 209.07 209.65 Td (the ) Tj ET Q q 0 0 0 rg BT 224.46 209.65 Td (option ) Tj ET Q q 0 0 0 rg BT 253.18 209.65 Td (in ) Tj ET Q q 0 0 0 rg BT 264.13 209.65 Td (February ) Tj ET Q q 0 0 0 rg BT 303.40 209.65 Td (2015 ) Tj ET Q q 0 0 0 rg BT 326.57 209.65 Td (and ) Tj ET Q q 0 0 0 rg BT 344.18 209.65 Td (acquired ) Tj ET Q q 0 0 0 rg BT 381.77 209.65 Td (the ) Tj ET Q q 0 0 0 rg BT 397.16 209.65 Td (business ) Tj ET Q q 0 0 0 rg BT 434.22 209.65 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 449.05 209.65 Td ($132 ) Tj ET Q q 0 0 0 rg BT 472.22 209.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.12 209.65 Td ( ) Tj ET Q q 0 0 0 rg BT 504.29 209.65 Td (resulting ) Tj ET Q q 0 0 0 rg BT 542.45 209.65 Td (in ) Tj ET Q q 0 0 0 rg BT 553.40 209.65 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.01 209.65 Td ($59 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 197.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 197.65 Td ( ) Tj ET Q q 0 0 0 rg BT 67.39 197.65 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 112.10 197.65 Td (gain.) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 172.08505859374998 m 68.412109375 172.08505859374998 l s q 0 0 0 rg BT 36.00 173.65 Td (V) Tj ET Q q 0 0 0 rg BT 42.30 173.65 Td (aleant) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.65 Td (In ) Tj ET Q q 0 0 0 rg BT 46.54 149.65 Td (October ) Tj ET Q q 0 0 0 rg BT 80.95 149.65 Td (2012, ) Tj ET Q q 0 0 0 rg BT 105.66 149.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 128.99 149.65 Td (transferred ) Tj ET Q q 0 0 0 rg BT 174.51 149.65 Td (to ) Tj ET Q q 0 0 0 rg BT 184.50 149.65 Td (PharmaSwiss ) Tj ET Q q 0 0 0 rg BT 240.60 149.65 Td (SA, ) Tj ET Q q 0 0 0 rg BT 258.09 149.65 Td (a ) Tj ET Q q 0 0 0 rg BT 264.73 149.65 Td (wholly-owned ) Tj ET Q q 0 0 0 rg BT 324.71 149.65 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 368.03 149.65 Td (of ) Tj ET Q q 0 0 0 rg BT 378.41 149.65 Td (V) Tj ET Q q 0 0 0 rg BT 384.52 149.65 Td (aleant ) Tj ET Q q 0 0 0 rg BT 410.60 149.65 Td (the ) Tj ET Q q 0 0 0 rg BT 425.03 149.65 Td (right ) Tj ET Q q 0 0 0 rg BT 446.12 149.65 Td (to ) Tj ET Q q 0 0 0 rg BT 456.11 149.65 Td (sell, ) Tj ET Q q 0 0 0 rg BT 474.70 149.65 Td (distribute, ) Tj ET Q q 0 0 0 rg BT 517.19 149.65 Td (and ) Tj ET Q q 0 0 0 rg BT 533.83 149.65 Td (market ) Tj ET Q q 0 0 0 rg BT 563.80 149.65 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.65 Td (certain ) Tj ET Q q 0 0 0 rg BT 65.70 137.65 Td (mature ) Tj ET Q q 0 0 0 rg BT 95.97 137.65 Td (brand ) Tj ET Q q 0 0 0 rg BT 121.23 137.65 Td (products ) Tj ET Q q 0 0 0 rg BT 158.17 137.65 Td (in ) Tj ET Q q 0 0 0 rg BT 168.45 137.65 Td (Europe ) Tj ET Q q 0 0 0 rg BT 199.83 137.65 Td (through ) Tj ET Q q 0 0 0 rg BT 233.44 137.65 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 292.02 137.65 Td (2014.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 116.05 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.26 116.05 Td (also ) Tj ET Q q 0 0 0 rg BT 79.50 116.05 Td (granted ) Tj ET Q q 0 0 0 rg BT 112.39 116.05 Td (V) Tj ET Q q 0 0 0 rg BT 118.50 116.05 Td (aleant ) Tj ET Q q 0 0 0 rg BT 145.50 116.05 Td (an ) Tj ET Q q 0 0 0 rg BT 158.08 116.05 Td (option ) Tj ET Q q 0 0 0 rg BT 186.76 116.05 Td (to ) Tj ET Q q 0 0 0 rg BT 197.68 116.05 Td (acquire ) Tj ET Q q 0 0 0 rg BT 230.23 116.05 Td (the ) Tj ET Q q 0 0 0 rg BT 245.58 116.05 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 293.14 116.05 Td (and ) Tj ET Q q 0 0 0 rg BT 310.71 116.05 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 358.26 116.05 Td (property ) Tj ET Q q 0 0 0 rg BT 395.27 116.05 Td (exclusively ) Tj ET Q q 0 0 0 rg BT 443.95 116.05 Td (related ) Tj ET Q q 0 0 0 rg BT 474.28 116.05 Td (to ) Tj ET Q q 0 0 0 rg BT 485.19 116.05 Td (the ) Tj ET Q q 0 0 0 rg BT 500.54 116.05 Td (products ) Tj ET Q q 0 0 0 rg BT 538.11 116.05 Td (at ) Tj ET Q q 0 0 0 rg BT 548.46 116.05 Td (a ) Tj ET Q q 0 0 0 rg BT 556.03 116.05 Td (price ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 104.05 Td (determined ) Tj ET Q q 0 0 0 rg BT 83.10 104.05 Td (based ) Tj ET Q q 0 0 0 rg BT 107.99 104.05 Td (on ) Tj ET Q q 0 0 0 rg BT 120.10 104.05 Td (a ) Tj ET Q q 0 0 0 rg BT 126.66 104.05 Td (multiple ) Tj ET Q q 0 0 0 rg BT 162.11 104.05 Td (of ) Tj ET Q q 0 0 0 rg BT 172.56 104.05 Td (sales. ) Tj ET Q q 0 0 0 rg BT 196.46 104.05 Td (V) Tj ET Q q 0 0 0 rg BT 202.57 104.05 Td (aleant ) Tj ET Q q 0 0 0 rg BT 228.56 104.05 Td (exercised ) Tj ET Q q 0 0 0 rg BT 268.44 104.05 Td (the ) Tj ET Q q 0 0 0 rg BT 282.77 104.05 Td (option ) Tj ET Q q 0 0 0 rg BT 310.45 104.05 Td (in ) Tj ET Q q 0 0 0 rg BT 320.34 104.05 Td (January ) Tj ET Q q 0 0 0 rg BT 353.56 104.05 Td (2015 ) Tj ET Q q 0 0 0 rg BT 375.68 104.05 Td (and ) Tj ET Q q 0 0 0 rg BT 392.23 104.05 Td (acquired ) Tj ET Q q 0 0 0 rg BT 428.78 104.05 Td (the ) Tj ET Q q 0 0 0 rg BT 443.11 104.05 Td (business ) Tj ET Q q 0 0 0 rg BT 479.12 104.05 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.90 104.05 Td ($61 ) Tj ET Q q 0 0 0 rg BT 510.02 104.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 538.91 104.05 Td ( ) Tj ET Q q 0 0 0 rg BT 541.03 104.05 Td (resulting ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 92.05 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 92.05 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 58.22 92.05 Td ($88 ) Tj ET Q q 0 0 0 rg BT 75.72 92.05 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 104.61 92.05 Td ( ) Tj ET Q q 0 0 0 rg BT 107.11 92.05 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 151.82 92.05 Td (gain. ) Tj ET Q endstream endobj 153 0 obj <> endobj 154 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (76) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 749.25 Td (4) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 749.25 Td (. ) Tj ET Q q 0 0 0 rg BT 67.94 749.25 Td (ACQUISITIONS, DIVESTITURES ) Tj ET Q q 0 0 0 rg BT 223.27 749.25 Td (AND LICENSING ) Tj ET Q q 0 0 0 rg BT 305.51 749.25 Td (ARRANGEMENTS) Tj ET Q BT /F4 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 723.68505859375 m 87.1279296875 723.68505859375 l s q 0 0 0 rg BT 36.00 725.25 Td (Acquisitions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 707.25 Td (Acquisitions ) Tj ET Q q 0 0 0 rg BT 88.69 707.25 Td (are ) Tj ET Q q 0 0 0 rg BT 103.03 707.25 Td (evaluated ) Tj ET Q q 0 0 0 rg BT 143.47 707.25 Td (to ) Tj ET Q q 0 0 0 rg BT 153.38 707.25 Td (determine ) Tj ET Q q 0 0 0 rg BT 195.49 707.25 Td (whether ) Tj ET Q q 0 0 0 rg BT 229.83 707.25 Td (it ) Tj ET Q q 0 0 0 rg BT 237.52 707.25 Td (is ) Tj ET Q q 0 0 0 rg BT 246.32 707.25 Td (a ) Tj ET Q q 0 0 0 rg BT 252.89 707.25 Td (business, ) Tj ET Q q 0 0 0 rg BT 291.41 707.25 Td (an ) Tj ET Q q 0 0 0 rg BT 302.98 707.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 324.55 707.25 Td (or ) Tj ET Q q 0 0 0 rg BT 335.01 707.25 Td (a ) Tj ET Q q 0 0 0 rg BT 341.58 707.25 Td (group ) Tj ET Q q 0 0 0 rg BT 367.04 707.25 Td (of ) Tj ET Q q 0 0 0 rg BT 377.50 707.25 Td (assets. ) Tj ET Q q 0 0 0 rg BT 405.31 707.25 Td (The ) Tj ET Q q 0 0 0 rg BT 422.99 707.25 Td (following ) Tj ET Q q 0 0 0 rg BT 464.01 707.25 Td (transactions ) Tj ET Q q 0 0 0 rg BT 513.90 707.25 Td (were ) Tj ET Q q 0 0 0 rg BT 535.46 707.25 Td (accounted ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 695.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.59 695.25 Td (as ) Tj ET Q q 0 0 0 rg BT 61.85 695.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 84.22 695.25 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 134.93 695.25 Td (since ) Tj ET Q q 0 0 0 rg BT 158.40 695.25 Td (they ) Tj ET Q q 0 0 0 rg BT 178.55 695.25 Td (were ) Tj ET Q q 0 0 0 rg BT 200.91 695.25 Td (determined ) Tj ET Q q 0 0 0 rg BT 248.82 695.25 Td (not ) Tj ET Q q 0 0 0 rg BT 264.53 695.25 Td (to ) Tj ET Q q 0 0 0 rg BT 275.24 695.25 Td (be ) Tj ET Q q 0 0 0 rg BT 287.61 695.25 Td (a ) Tj ET Q q 0 0 0 rg BT 294.98 695.25 Td (business ) Tj ET Q q 0 0 0 rg BT 331.81 695.25 Td (as ) Tj ET Q q 0 0 0 rg BT 343.07 695.25 Td (that ) Tj ET Q q 0 0 0 rg BT 360.99 695.25 Td (term ) Tj ET Q q 0 0 0 rg BT 382.25 695.25 Td (is ) Tj ET Q q 0 0 0 rg BT 391.85 695.25 Td (defined ) Tj ET Q q 0 0 0 rg BT 424.77 695.25 Td (in ) Tj ET Q q 0 0 0 rg BT 434.83 695.25 Td (ASC ) Tj ET Q q 0 0 0 rg BT 457.21 695.25 Td (805 ) Tj ET Q q 0 0 0 rg BT 475.14 695.25 Td (- ) Tj ET Q q 0 0 0 rg BT 481.41 695.25 Td (Business ) Tj ET Q q 0 0 0 rg BT 519.90 695.25 Td (Combinations ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 683.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 75.50 683.25 Td (because ) Tj ET Q q 0 0 0 rg BT 109.44 683.25 Td (no ) Tj ET Q q 0 0 0 rg BT 121.73 683.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 166.24 683.25 Td (processes ) Tj ET Q q 0 0 0 rg BT 206.85 683.25 Td (were ) Tj ET Q q 0 0 0 rg BT 228.57 683.25 Td (acquired. ) Tj ET Q q 0 0 0 rg BT 267.28 683.25 Td (As ) Tj ET Q q 0 0 0 rg BT 280.68 683.25 Td (a ) Tj ET Q q 0 0 0 rg BT 287.41 683.25 Td (result, ) Tj ET Q q 0 0 0 rg BT 314.42 683.25 Td (the ) Tj ET Q q 0 0 0 rg BT 328.93 683.25 Td (amounts ) Tj ET Q q 0 0 0 rg BT 365.11 683.25 Td (allocated ) Tj ET Q q 0 0 0 rg BT 403.49 683.25 Td (to ) Tj ET Q q 0 0 0 rg BT 413.56 683.25 Td (the ) Tj ET Q q 0 0 0 rg BT 428.06 683.25 Td (lead ) Tj ET Q q 0 0 0 rg BT 447.01 683.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 508.18 683.25 Td (compounds ) Tj ET Q q 0 0 0 rg BT 556.58 683.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 671.25 Td (expensed ) Tj ET Q q 0 0 0 rg BT 75.71 671.25 Td (and ) Tj ET Q q 0 0 0 rg BT 92.65 671.25 Td (not ) Tj ET Q q 0 0 0 rg BT 107.92 671.25 Td (capitalized. ) Tj ET Q q 0 0 0 rg BT 156.05 671.25 Td (The ) Tj ET Q q 0 0 0 rg BT 174.10 671.25 Td (consideration ) Tj ET Q q 0 0 0 rg BT 230.47 671.25 Td (of ) Tj ET Q q 0 0 0 rg BT 241.30 671.25 Td (each ) Tj ET Q q 0 0 0 rg BT 262.11 671.25 Td (transaction ) Tj ET Q q 0 0 0 rg BT 308.49 671.25 Td (was ) Tj ET Q q 0 0 0 rg BT 326.54 671.25 Td (allocated ) Tj ET Q q 0 0 0 rg BT 365.13 671.25 Td (as ) Tj ET Q q 0 0 0 rg BT 375.96 671.25 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 639.75 194.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 229.50 639.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 639.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 283.50 639.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 287.50 639.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 639.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 639.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 639.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 639.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 639.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 639.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 617.75 194.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 229.50 617.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 617.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 283.50 617.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 287.50 617.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 617.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 617.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 617.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 617.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 617.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 617.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 587.75 194.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 229.50 587.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 587.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 283.50 587.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 287.50 587.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 587.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 587.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 587.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 587.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 587.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 587.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 565.75 194.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 229.50 565.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 565.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 283.50 565.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 287.50 565.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 565.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 565.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 565.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 565.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 565.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 565.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 535.75 194.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 229.50 535.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 535.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 283.50 535.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 287.50 535.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 535.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 535.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 535.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 535.75 69.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 535.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 535.75 69.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 233.5 639.75 m 283.5 639.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 287.5 639.75 m 356.5 639.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 639.75 m 429.5 639.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 639.75 m 502.5 639.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 639.75 m 575.5 639.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 287.5 587.75 m 356.5 587.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 587.75 m 429.5 587.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 587.75 m 502.5 587.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 587.75 m 575.5 587.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 287.5 535.75 m 356.5 535.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 535.75 m 429.5 535.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 535.75 m 502.5 535.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 535.75 m 575.5 535.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 644.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 250.05 643.98 Td (Y) Tj ET Q q 0 0 0 rg BT 255.38 643.98 Td (ear) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 291.65 643.98 Td (Upfr) Tj ET Q q 0 0 0 rg BT 308.02 643.98 Td (ont Payment) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 370.15 643.98 Td (R&D Expense) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 445.00 651.98 Td (Deferr) Tj ET Q q 0 0 0 rg BT 467.50 651.98 Td (ed ) Tj ET Q q 0 0 0 rg BT 477.36 651.98 Td (T) Tj ET Q q 0 0 0 rg BT 481.96 651.98 Td (ax ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 453.80 643.98 Td (Assets) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 475.13 647.61 Td (\(a\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 521.35 651.98 Td (Contingent) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 516.25 643.98 Td (Consideration) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 629.42 Td (IFM) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 55.78 633.95 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.00 629.42 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.00 629.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.65 629.42 Td (325) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 629.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 629.42 Td (31) Tj ET Q q 0 0 0 rg BT 420.65 629.42 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 629.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 629.42 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 629.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 629.42 Td (2,020) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 607.42 Td (Cormorant) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.00 607.42 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.65 607.42 Td (35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 607.42 Td (35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 607.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 607.42 Td (485) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 592.42 Td (Padlock) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.00 592.42 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.65 592.42 Td (150) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 592.42 Td (139) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 592.42 Td (1) Tj ET Q q 0 0 0 rg BT 493.65 592.42 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 592.42 Td (453) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.00 577.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.65 577.42 Td (185) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 577.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 577.42 Td (174) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 577.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 577.42 Td (1) Tj ET Q q 0 0 0 rg BT 493.65 577.42 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 577.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 577.42 Td (938) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 555.42 Td (Cardioxyl) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.00 555.42 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.00 555.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.65 555.42 Td (200) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 555.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 555.42 Td (167) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 555.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 555.42 Td (33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 555.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 555.42 Td (1,875) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 540.42 Td (Flexus) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 64.67 544.95 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.00 540.42 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.65 540.42 Td (814) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 540.42 Td (800) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 540.42 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 540.42 Td (450) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 290.00 525.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 330.15 525.42 Td (1,014) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 525.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 525.42 Td (967) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 525.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 525.42 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 525.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 525.42 Td (2,325) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 511.65 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 54.00 511.65 Td (Relates ) Tj ET Q q 0 0 0 rg BT 79.55 511.65 Td (to ) Tj ET Q q 0 0 0 rg BT 87.77 511.65 Td (net ) Tj ET Q q 0 0 0 rg BT 99.54 511.65 Td (operating ) Tj ET Q q 0 0 0 rg BT 131.75 511.65 Td (loss ) Tj ET Q q 0 0 0 rg BT 146.20 511.65 Td (and ) Tj ET Q q 0 0 0 rg BT 159.75 511.65 Td (tax ) Tj ET Q q 0 0 0 rg BT 171.53 511.65 Td (credit ) Tj ET Q q 0 0 0 rg BT 191.74 511.65 Td (carryforwards.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 499.05 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 54.00 499.05 Td (Includes ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 83.41 499.05 Td ($25 ) Tj ET Q q 0 0 0 rg BT 97.71 499.05 Td (million) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 120.83 499.05 Td ( ) Tj ET Q q 0 0 0 rg BT 123.13 499.05 Td (for ) Tj ET Q q 0 0 0 rg BT 134.77 499.05 Td (certain ) Tj ET Q q 0 0 0 rg BT 158.83 499.05 Td (negotiation ) Tj ET Q q 0 0 0 rg BT 197.13 499.05 Td (rights ) Tj ET Q q 0 0 0 rg BT 217.66 499.05 Td (to ) Tj ET Q q 0 0 0 rg BT 226.19 499.05 Td (collaborate, ) Tj ET Q q 0 0 0 rg BT 266.03 499.05 Td (license ) Tj ET Q q 0 0 0 rg BT 290.54 499.05 Td (or ) Tj ET Q q 0 0 0 rg BT 299.51 499.05 Td (acquire ) Tj ET Q q 0 0 0 rg BT 325.36 499.05 Td (an ) Tj ET Q q 0 0 0 rg BT 335.22 499.05 Td (NLRP3 ) Tj ET Q q 0 0 0 rg BT 361.97 499.05 Td (antagonist ) Tj ET Q q 0 0 0 rg BT 397.16 499.05 Td (program ) Tj ET Q q 0 0 0 rg BT 426.57 499.05 Td (from ) Tj ET Q q 0 0 0 rg BT 444.42 499.05 Td (a ) Tj ET Q q 0 0 0 rg BT 450.28 499.05 Td (newly ) Tj ET Q q 0 0 0 rg BT 472.14 499.05 Td (formed ) Tj ET Q q 0 0 0 rg BT 497.54 499.05 Td (entity ) Tj ET Q q 0 0 0 rg BT 518.07 499.05 Td (established ) Tj ET Q q 0 0 0 rg BT 555.92 499.05 Td (by ) Tj ET Q q 0 0 0 rg BT 566.23 499.05 Td (the ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 54.00 489.45 Td (former ) Tj ET Q q 0 0 0 rg BT 77.77 489.45 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 120.20 489.45 Td (of ) Tj ET Q q 0 0 0 rg BT 128.86 489.45 Td (IFM. ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 476.85 Td (\(c\) ) Tj ET Q q 0 0 0 rg BT 46.88 476.85 Td ( ) Tj ET Q q 0 0 0 rg BT 48.88 476.85 Td ( ) Tj ET Q q 0 0 0 rg BT 50.88 476.85 Td ( ) Tj ET Q q 0 0 0 rg BT 52.88 476.85 Td ( ) Tj ET Q q 0 0 0 rg BT 54.88 476.85 Td (Includes ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 83.98 476.85 Td ($14 ) Tj ET Q q 0 0 0 rg BT 97.98 476.85 Td (million) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 121.09 476.85 Td ( ) Tj ET Q q 0 0 0 rg BT 123.09 476.85 Td (of ) Tj ET Q q 0 0 0 rg BT 131.76 476.85 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 168.86 476.85 Td (costs.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 441.3169921875 m 53.7685546875 441.3169921875 l s q 0 0 0 rg BT 36.00 442.65 Td (IFM) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 427.65 Td (In ) Tj ET Q q 0 0 0 rg BT 47.49 427.65 Td (2017, ) Tj ET Q q 0 0 0 rg BT 73.16 427.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 97.45 427.65 Td (acquired ) Tj ET Q q 0 0 0 rg BT 135.03 427.65 Td (all ) Tj ET Q q 0 0 0 rg BT 148.19 427.65 Td (of ) Tj ET Q q 0 0 0 rg BT 159.69 427.65 Td (the ) Tj ET Q q 0 0 0 rg BT 175.07 427.65 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 224.90 427.65 Td (shares ) Tj ET Q q 0 0 0 rg BT 253.05 427.65 Td (of ) Tj ET Q q 0 0 0 rg BT 264.54 427.65 Td (IFM, ) Tj ET Q q 0 0 0 rg BT 287.99 427.65 Td (a ) Tj ET Q q 0 0 0 rg BT 295.59 427.65 Td (private ) Tj ET Q q 0 0 0 rg BT 326.52 427.65 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 386.90 427.65 Td (company ) Tj ET Q q 0 0 0 rg BT 426.72 427.65 Td (focused ) Tj ET Q q 0 0 0 rg BT 460.98 427.65 Td (on ) Tj ET Q q 0 0 0 rg BT 474.14 427.65 Td (developing ) Tj ET Q q 0 0 0 rg BT 521.74 427.65 Td (therapies ) Tj ET Q q 0 0 0 rg BT 561.00 427.65 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 415.65 Td (modulate ) Tj ET Q q 0 0 0 rg BT 75.58 415.65 Td (novel ) Tj ET Q q 0 0 0 rg BT 100.17 415.65 Td (tar) Tj ET Q q 0 0 0 rg BT 110.54 415.65 Td (gets ) Tj ET Q q 0 0 0 rg BT 129.02 415.65 Td (in ) Tj ET Q q 0 0 0 rg BT 139.17 415.65 Td (the ) Tj ET Q q 0 0 0 rg BT 153.76 415.65 Td (innate ) Tj ET Q q 0 0 0 rg BT 180.57 415.65 Td (immune ) Tj ET Q q 0 0 0 rg BT 215.72 415.65 Td (system ) Tj ET Q q 0 0 0 rg BT 245.87 415.65 Td (to ) Tj ET Q q 0 0 0 rg BT 256.02 415.65 Td (treat ) Tj ET Q q 0 0 0 rg BT 276.16 415.65 Td (cancer) Tj ET Q q 0 0 0 rg BT 301.84 415.65 Td (, ) Tj ET Q q 0 0 0 rg BT 306.71 415.65 Td (autoimmunity ) Tj ET Q q 0 0 0 rg BT 365.19 415.65 Td (and ) Tj ET Q q 0 0 0 rg BT 382.01 415.65 Td (inflammatory ) Tj ET Q q 0 0 0 rg BT 438.81 415.65 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 476.28 415.65 Td (The ) Tj ET Q q 0 0 0 rg BT 494.20 415.65 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 540.45 415.65 Td (provided ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 403.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.84 403.65 Td (with ) Tj ET Q q 0 0 0 rg BT 80.34 403.65 Td (full ) Tj ET Q q 0 0 0 rg BT 96.94 403.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 122.44 403.65 Td (to ) Tj ET Q q 0 0 0 rg BT 132.93 403.65 Td (IFM's ) Tj ET Q q 0 0 0 rg BT 159.13 403.65 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 204.04 403.65 Td (STING ) Tj ET Q q 0 0 0 rg BT 236.20 403.65 Td (and ) Tj ET Q q 0 0 0 rg BT 253.36 403.65 Td (NLRP3 ) Tj ET Q q 0 0 0 rg BT 286.63 403.65 Td (agonist ) Tj ET Q q 0 0 0 rg BT 318.24 403.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 358.72 403.65 Td (focused ) Tj ET Q q 0 0 0 rg BT 392.54 403.65 Td (on ) Tj ET Q q 0 0 0 rg BT 405.26 403.65 Td (enhancing ) Tj ET Q q 0 0 0 rg BT 449.07 403.65 Td (the ) Tj ET Q q 0 0 0 rg BT 464.00 403.65 Td (innate ) Tj ET Q q 0 0 0 rg BT 491.15 403.65 Td (immune ) Tj ET Q q 0 0 0 rg BT 526.64 403.65 Td (response ) Tj ET Q q 0 0 0 rg BT 564.35 403.65 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 391.65 Td (treating ) Tj ET Q q 0 0 0 rg BT 69.50 391.65 Td (cancer) Tj ET Q q 0 0 0 rg BT 95.03 391.65 Td (. ) Tj ET Q q 0 0 0 rg BT 100.48 391.65 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 147.88 391.65 Td (consideration ) Tj ET Q q 0 0 0 rg BT 204.71 391.65 Td (includes ) Tj ET Q q 0 0 0 rg BT 240.99 391.65 Td (development, ) Tj ET Q q 0 0 0 rg BT 298.09 391.65 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 342.14 391.65 Td (and ) Tj ET Q q 0 0 0 rg BT 359.53 391.65 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 408.02 391.65 Td (milestone ) Tj ET Q q 0 0 0 rg BT 449.86 391.65 Td (payments. ) Tj ET Q q 0 0 0 rg BT 493.64 391.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 517.71 391.65 Td (may ) Tj ET Q q 0 0 0 rg BT 537.88 391.65 Td (pay ) Tj ET Q q 0 0 0 rg BT 555.28 391.65 Td (up ) Tj ET Q q 0 0 0 rg BT 568.23 391.65 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 379.65 Td ($555 ) Tj ET Q q 0 0 0 rg BT 57.93 379.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 86.82 379.65 Td ( ) Tj ET Q q 0 0 0 rg BT 88.74 379.65 Td (in ) Tj ET Q q 0 0 0 rg BT 98.45 379.65 Td (additional ) Tj ET Q q 0 0 0 rg BT 140.37 379.65 Td (contingent ) Tj ET Q q 0 0 0 rg BT 184.50 379.65 Td (milestones ) Tj ET Q q 0 0 0 rg BT 229.20 379.65 Td (for ) Tj ET Q q 0 0 0 rg BT 242.79 379.65 Td (any ) Tj ET Q q 0 0 0 rg BT 259.15 379.65 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 305.52 379.65 Td (products ) Tj ET Q q 0 0 0 rg BT 341.88 379.65 Td (selected ) Tj ET Q q 0 0 0 rg BT 376.01 379.65 Td (from ) Tj ET Q q 0 0 0 rg BT 397.38 379.65 Td (IFM's ) Tj ET Q q 0 0 0 rg BT 422.78 379.65 Td (preclinical ) Tj ET Q q 0 0 0 rg BT 466.90 379.65 Td (STING ) Tj ET Q q 0 0 0 rg BT 498.27 379.65 Td (and ) Tj ET Q q 0 0 0 rg BT 514.64 379.65 Td (NLRP3 ) Tj ET Q q 0 0 0 rg BT 547.13 379.65 Td (agonist ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 367.65 Td (programs ) Tj ET Q q 0 0 0 rg BT 76.27 367.65 Td (which ) Tj ET Q q 0 0 0 rg BT 103.21 367.65 Td (is ) Tj ET Q q 0 0 0 rg BT 112.38 367.65 Td (not ) Tj ET Q q 0 0 0 rg BT 127.66 367.65 Td (included ) Tj ET Q q 0 0 0 rg BT 164.59 367.65 Td (in ) Tj ET Q q 0 0 0 rg BT 174.87 367.65 Td (the ) Tj ET Q q 0 0 0 rg BT 189.58 367.65 Td (contingent ) Tj ET Q q 0 0 0 rg BT 234.30 367.65 Td (consideration ) Tj ET Q q 0 0 0 rg BT 290.67 367.65 Td (amount ) Tj ET Q q 0 0 0 rg BT 323.16 367.65 Td (in ) Tj ET Q q 0 0 0 rg BT 333.44 367.65 Td (the ) Tj ET Q q 0 0 0 rg BT 348.16 367.65 Td (table ) Tj ET Q q 0 0 0 rg BT 370.09 367.65 Td (above.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 342.3169921875 m 80.453125 342.3169921875 l s q 0 0 0 rg BT 36.00 343.65 Td (Cormorant) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 328.65 Td (In ) Tj ET Q q 0 0 0 rg BT 47.17 328.65 Td (2016, ) Tj ET Q q 0 0 0 rg BT 72.52 328.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 96.49 328.65 Td (acquired ) Tj ET Q q 0 0 0 rg BT 133.75 328.65 Td (all ) Tj ET Q q 0 0 0 rg BT 146.59 328.65 Td (of ) Tj ET Q q 0 0 0 rg BT 157.77 328.65 Td (the ) Tj ET Q q 0 0 0 rg BT 172.83 328.65 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 222.34 328.65 Td (shares ) Tj ET Q q 0 0 0 rg BT 250.17 328.65 Td (of ) Tj ET Q q 0 0 0 rg BT 261.35 328.65 Td (Cormorant, ) Tj ET Q q 0 0 0 rg BT 310.02 328.65 Td (a ) Tj ET Q q 0 0 0 rg BT 317.30 328.65 Td (private ) Tj ET Q q 0 0 0 rg BT 347.91 328.65 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 411.83 328.65 Td (company ) Tj ET Q q 0 0 0 rg BT 451.32 328.65 Td (focused ) Tj ET Q q 0 0 0 rg BT 485.27 328.65 Td (on ) Tj ET Q q 0 0 0 rg BT 498.11 328.65 Td (the ) Tj ET Q q 0 0 0 rg BT 513.17 328.65 Td (development ) Tj ET Q q 0 0 0 rg BT 567.67 328.65 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 316.65 Td (therapies ) Tj ET Q q 0 0 0 rg BT 74.21 316.65 Td (for ) Tj ET Q q 0 0 0 rg BT 87.99 316.65 Td (cancer ) Tj ET Q q 0 0 0 rg BT 116.19 316.65 Td (and ) Tj ET Q q 0 0 0 rg BT 132.74 316.65 Td (rare ) Tj ET Q q 0 0 0 rg BT 150.39 316.65 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 187.62 316.65 Td (The ) Tj ET Q q 0 0 0 rg BT 205.29 316.65 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 251.28 316.65 Td (provided ) Tj ET Q q 0 0 0 rg BT 288.95 316.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 312.18 316.65 Td (with ) Tj ET Q q 0 0 0 rg BT 332.08 316.65 Td (full ) Tj ET Q q 0 0 0 rg BT 348.08 316.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 372.98 316.65 Td (to ) Tj ET Q q 0 0 0 rg BT 382.87 316.65 Td (Cormorant's ) Tj ET Q q 0 0 0 rg BT 434.00 316.65 Td (lead ) Tj ET Q q 0 0 0 rg BT 452.77 316.65 Td (candidate ) Tj ET Q q 0 0 0 rg BT 493.20 316.65 Td (HuMax-IL8, ) Tj ET Q q 0 0 0 rg BT 546.14 316.65 Td (a ) Tj ET Q q 0 0 0 rg BT 552.69 316.65 Td (Phase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 304.65 Td (I/II ) Tj ET Q q 0 0 0 rg BT 50.37 304.65 Td (monoclonal ) Tj ET Q q 0 0 0 rg BT 99.18 304.65 Td (antibody ) Tj ET Q q 0 0 0 rg BT 135.77 304.65 Td (that ) Tj ET Q q 0 0 0 rg BT 152.37 304.65 Td (represents ) Tj ET Q q 0 0 0 rg BT 194.50 304.65 Td (a ) Tj ET Q q 0 0 0 rg BT 200.54 304.65 Td (potentially ) Tj ET Q q 0 0 0 rg BT 244.91 304.65 Td (complementary ) Tj ET Q q 0 0 0 rg BT 308.71 304.65 Td (immuno-oncology ) Tj ET Q q 0 0 0 rg BT 384.19 304.65 Td (mechanism ) Tj ET Q q 0 0 0 rg BT 431.33 304.65 Td (of ) Tj ET Q q 0 0 0 rg BT 441.26 304.65 Td (action ) Tj ET Q q 0 0 0 rg BT 467.29 304.65 Td (to ) Tj ET Q q 0 0 0 rg BT 476.55 304.65 Td (T) Tj ET Q q 0 0 0 rg BT 481.74 304.65 Td (-cell ) Tj ET Q q 0 0 0 rg BT 501.10 304.65 Td (directed ) Tj ET Q q 0 0 0 rg BT 534.91 304.65 Td (antibodies ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 292.65 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 292.65 Td (co-stimulatory ) Tj ET Q q 0 0 0 rg BT 113.76 292.65 Td (molecules. ) Tj ET Q q 0 0 0 rg BT 159.30 292.65 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 206.24 292.65 Td (consideration ) Tj ET Q q 0 0 0 rg BT 262.62 292.65 Td (includes ) Tj ET Q q 0 0 0 rg BT 298.44 292.65 Td (development ) Tj ET Q q 0 0 0 rg BT 352.59 292.65 Td (and ) Tj ET Q q 0 0 0 rg BT 369.53 292.65 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 413.12 292.65 Td (milestone ) Tj ET Q q 0 0 0 rg BT 454.51 292.65 Td (payments.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 267.3169921875 m 68.763671875 267.3169921875 l s q 0 0 0 rg BT 36.00 268.65 Td (Padlock) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 68.76 268.65 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 253.65 Td (In ) Tj ET Q q 0 0 0 rg BT 46.79 253.65 Td (2016, ) Tj ET Q q 0 0 0 rg BT 71.76 253.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 95.35 253.65 Td (acquired ) Tj ET Q q 0 0 0 rg BT 132.24 253.65 Td (all ) Tj ET Q q 0 0 0 rg BT 144.70 253.65 Td (of ) Tj ET Q q 0 0 0 rg BT 155.49 253.65 Td (the ) Tj ET Q q 0 0 0 rg BT 170.17 253.65 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 219.30 253.65 Td (shares ) Tj ET Q q 0 0 0 rg BT 246.76 253.65 Td (of ) Tj ET Q q 0 0 0 rg BT 257.55 253.65 Td (Padlock, ) Tj ET Q q 0 0 0 rg BT 294.73 253.65 Td (a ) Tj ET Q q 0 0 0 rg BT 301.64 253.65 Td (private ) Tj ET Q q 0 0 0 rg BT 331.87 253.65 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 391.54 253.65 Td (company ) Tj ET Q q 0 0 0 rg BT 430.66 253.65 Td (dedicated ) Tj ET Q q 0 0 0 rg BT 471.44 253.65 Td (to ) Tj ET Q q 0 0 0 rg BT 481.68 253.65 Td (creating ) Tj ET Q q 0 0 0 rg BT 516.35 253.65 Td (new ) Tj ET Q q 0 0 0 rg BT 535.47 253.65 Td (medicines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.65 Td (to ) Tj ET Q q 0 0 0 rg BT 46.25 241.65 Td (treat ) Tj ET Q q 0 0 0 rg BT 66.49 241.65 Td (destructive ) Tj ET Q q 0 0 0 rg BT 112.83 241.65 Td (autoimmune ) Tj ET Q q 0 0 0 rg BT 165.29 241.65 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 202.85 241.65 Td (The ) Tj ET Q q 0 0 0 rg BT 220.87 241.65 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 267.23 241.65 Td (provided ) Tj ET Q q 0 0 0 rg BT 305.25 241.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 328.84 241.65 Td (with ) Tj ET Q q 0 0 0 rg BT 349.09 241.65 Td (full ) Tj ET Q q 0 0 0 rg BT 365.45 241.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 390.70 241.65 Td (to ) Tj ET Q q 0 0 0 rg BT 400.95 241.65 Td (Padlock’) Tj ET Q q 0 0 0 rg BT 435.95 241.65 Td (s ) Tj ET Q q 0 0 0 rg BT 442.31 241.65 Td (P) Tj ET Q q 0 0 0 rg BT 446.96 241.65 Td (AD ) Tj ET Q q 0 0 0 rg BT 463.87 241.65 Td (inhibitor ) Tj ET Q q 0 0 0 rg BT 500.79 241.65 Td (discovery ) Tj ET Q q 0 0 0 rg BT 542.14 241.65 Td (program ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 229.65 Td (focused ) Tj ET Q q 0 0 0 rg BT 69.60 229.65 Td (on ) Tj ET Q q 0 0 0 rg BT 82.09 229.65 Td (the ) Tj ET Q q 0 0 0 rg BT 96.81 229.65 Td (development ) Tj ET Q q 0 0 0 rg BT 150.96 229.65 Td (of ) Tj ET Q q 0 0 0 rg BT 161.78 229.65 Td (potentially ) Tj ET Q q 0 0 0 rg BT 207.05 229.65 Td (transformational ) Tj ET Q q 0 0 0 rg BT 275.64 229.65 Td (treatment ) Tj ET Q q 0 0 0 rg BT 315.89 229.65 Td (approaches ) Tj ET Q q 0 0 0 rg BT 363.37 229.65 Td (for ) Tj ET Q q 0 0 0 rg BT 377.52 229.65 Td (patients ) Tj ET Q q 0 0 0 rg BT 411.12 229.65 Td (with ) Tj ET Q q 0 0 0 rg BT 431.40 229.65 Td (rheumatoid ) Tj ET Q q 0 0 0 rg BT 479.44 229.65 Td (arthritis. ) Tj ET Q q 0 0 0 rg BT 515.54 229.65 Td (Padlock’) Tj ET Q q 0 0 0 rg BT 550.54 229.65 Td (s ) Tj ET Q q 0 0 0 rg BT 556.93 229.65 Td (P) Tj ET Q q 0 0 0 rg BT 561.57 229.65 Td (AD ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.65 Td (discovery ) Tj ET Q q 0 0 0 rg BT 78.20 217.65 Td (program ) Tj ET Q q 0 0 0 rg BT 115.40 217.65 Td (may ) Tj ET Q q 0 0 0 rg BT 135.94 217.65 Td (have ) Tj ET Q q 0 0 0 rg BT 158.14 217.65 Td (additional ) Tj ET Q q 0 0 0 rg BT 201.45 217.65 Td (utility ) Tj ET Q q 0 0 0 rg BT 228.67 217.65 Td (in ) Tj ET Q q 0 0 0 rg BT 239.77 217.65 Td (treating ) Tj ET Q q 0 0 0 rg BT 273.63 217.65 Td (systemic ) Tj ET Q q 0 0 0 rg BT 311.95 217.65 Td (lupus ) Tj ET Q q 0 0 0 rg BT 336.94 217.65 Td (erythematosus ) Tj ET Q q 0 0 0 rg BT 398.03 217.65 Td (and ) Tj ET Q q 0 0 0 rg BT 415.79 217.65 Td (other ) Tj ET Q q 0 0 0 rg BT 439.66 217.65 Td (autoimmune ) Tj ET Q q 0 0 0 rg BT 492.97 217.65 Td (diseases. ) Tj ET Q q 0 0 0 rg BT 531.56 217.65 Td (Contingent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 205.65 Td (consideration ) Tj ET Q q 0 0 0 rg BT 92.37 205.65 Td (includes ) Tj ET Q q 0 0 0 rg BT 128.20 205.65 Td (development ) Tj ET Q q 0 0 0 rg BT 182.35 205.65 Td (and ) Tj ET Q q 0 0 0 rg BT 199.29 205.65 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 242.88 205.65 Td (milestone ) Tj ET Q q 0 0 0 rg BT 284.26 205.65 Td (payments.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 180.31699218749998 m 75.6240234375 180.31699218749998 l s q 0 0 0 rg BT 36.00 181.65 Td (Car) Tj ET Q q 0 0 0 rg BT 51.19 181.65 Td (dioxyl) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 75.62 181.65 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 166.65 Td (In ) Tj ET Q q 0 0 0 rg BT 47.90 166.65 Td (2015, ) Tj ET Q q 0 0 0 rg BT 73.98 166.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 98.68 166.65 Td (acquired ) Tj ET Q q 0 0 0 rg BT 136.67 166.65 Td (all ) Tj ET Q q 0 0 0 rg BT 150.24 166.65 Td (of ) Tj ET Q q 0 0 0 rg BT 162.15 166.65 Td (the ) Tj ET Q q 0 0 0 rg BT 177.94 166.65 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 228.18 166.65 Td (shares ) Tj ET Q q 0 0 0 rg BT 256.74 166.65 Td (of ) Tj ET Q q 0 0 0 rg BT 268.65 166.65 Td (Cardioxyl, ) Tj ET Q q 0 0 0 rg BT 314.72 166.65 Td (a ) Tj ET Q q 0 0 0 rg BT 322.73 166.65 Td (private ) Tj ET Q q 0 0 0 rg BT 354.07 166.65 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 414.85 166.65 Td (company ) Tj ET Q q 0 0 0 rg BT 455.08 166.65 Td (focused ) Tj ET Q q 0 0 0 rg BT 489.75 166.65 Td (on ) Tj ET Q q 0 0 0 rg BT 503.33 166.65 Td (the ) Tj ET Q q 0 0 0 rg BT 519.12 166.65 Td (discovery ) Tj ET Q q 0 0 0 rg BT 561.57 166.65 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 154.65 Td (development ) Tj ET Q q 0 0 0 rg BT 91.07 154.65 Td (of ) Tj ET Q q 0 0 0 rg BT 102.82 154.65 Td (novel ) Tj ET Q q 0 0 0 rg BT 128.46 154.65 Td (therapeutic ) Tj ET Q q 0 0 0 rg BT 176.30 154.65 Td (agents ) Tj ET Q q 0 0 0 rg BT 205.27 154.65 Td (for ) Tj ET Q q 0 0 0 rg BT 220.35 154.65 Td (cardiovascular ) Tj ET Q q 0 0 0 rg BT 282.08 154.65 Td (disease. ) Tj ET Q q 0 0 0 rg BT 316.63 154.65 Td (The ) Tj ET Q q 0 0 0 rg BT 335.60 154.65 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 382.90 154.65 Td (provided ) Tj ET Q q 0 0 0 rg BT 421.87 154.65 Td (BMS ) Tj ET Q q 0 0 0 rg BT 446.41 154.65 Td (with ) Tj ET Q q 0 0 0 rg BT 467.61 154.65 Td (full ) Tj ET Q q 0 0 0 rg BT 484.92 154.65 Td (rights ) Tj ET Q q 0 0 0 rg BT 511.12 154.65 Td (to ) Tj ET Q q 0 0 0 rg BT 522.32 154.65 Td (CXL-1427, ) Tj ET Q q 0 0 0 rg BT 571.58 154.65 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 142.65 Td (nitroxyl ) Tj ET Q q 0 0 0 rg BT 71.84 142.65 Td (prodrug ) Tj ET Q q 0 0 0 rg BT 107.68 142.65 Td (in ) Tj ET Q q 0 0 0 rg BT 119.64 142.65 Td (Phase ) Tj ET Q q 0 0 0 rg BT 147.14 142.65 Td (II ) Tj ET Q q 0 0 0 rg BT 157.98 142.65 Td (development ) Tj ET Q q 0 0 0 rg BT 213.81 142.65 Td (for ) Tj ET Q q 0 0 0 rg BT 229.65 142.65 Td (acute ) Tj ET Q q 0 0 0 rg BT 254.92 142.65 Td (decompensated ) Tj ET Q q 0 0 0 rg BT 320.74 142.65 Td (heart ) Tj ET Q q 0 0 0 rg BT 344.90 142.65 Td (failure. ) Tj ET Q q 0 0 0 rg BT 377.67 142.65 Td (Contingent ) Tj ET Q q 0 0 0 rg BT 426.29 142.65 Td (consideration ) Tj ET Q q 0 0 0 rg BT 484.34 142.65 Td (includes ) Tj ET Q q 0 0 0 rg BT 521.85 142.65 Td (development, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 130.65 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 78.41 130.65 Td (and ) Tj ET Q q 0 0 0 rg BT 94.17 130.65 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 141.02 130.65 Td (milestone ) Tj ET Q q 0 0 0 rg BT 181.22 130.65 Td (payments, ) Tj ET Q q 0 0 0 rg BT 223.37 130.65 Td (of ) Tj ET Q q 0 0 0 rg BT 233.02 130.65 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 258.77 130.65 Td ($100 ) Tj ET Q q 0 0 0 rg BT 280.09 130.65 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 308.98 130.65 Td ( ) Tj ET Q q 0 0 0 rg BT 310.30 130.65 Td (was ) Tj ET Q q 0 0 0 rg BT 327.17 130.65 Td (included ) Tj ET Q q 0 0 0 rg BT 362.92 130.65 Td (in ) Tj ET Q q 0 0 0 rg BT 372.02 130.65 Td (R&D ) Tj ET Q q 0 0 0 rg BT 395.01 130.65 Td (expense ) Tj ET Q q 0 0 0 rg BT 428.53 130.65 Td (in ) Tj ET Q q 0 0 0 rg BT 437.63 130.65 Td (2017 ) Tj ET Q q 0 0 0 rg BT 458.95 130.65 Td (following ) Tj ET Q q 0 0 0 rg BT 499.15 130.65 Td (the ) Tj ET Q q 0 0 0 rg BT 512.69 130.65 Td (commencement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 118.65 Td (of ) Tj ET Q q 0 0 0 rg BT 46.83 118.65 Td (a ) Tj ET Q q 0 0 0 rg BT 53.77 118.65 Td (Phase ) Tj ET Q q 0 0 0 rg BT 79.60 118.65 Td (II ) Tj ET Q q 0 0 0 rg BT 88.76 118.65 Td (clinical ) Tj ET Q q 0 0 0 rg BT 120.69 118.65 Td (study) Tj ET Q q 0 0 0 rg BT 141.71 118.65 Td (.) Tj ET Q endstream endobj 155 0 obj <> endobj 156 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (77) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 62.6552734375 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Flexus) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 62.66 749.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 734.10 Td (In ) Tj ET Q q 0 0 0 rg BT 45.81 734.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 69.79 734.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 92.39 734.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 128.29 734.10 Td (all ) Tj ET Q q 0 0 0 rg BT 139.77 734.10 Td (of ) Tj ET Q q 0 0 0 rg BT 149.58 734.10 Td (the ) Tj ET Q q 0 0 0 rg BT 163.28 734.10 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 211.42 734.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 237.89 734.10 Td (of ) Tj ET Q q 0 0 0 rg BT 247.70 734.10 Td (Flexus, ) Tj ET Q q 0 0 0 rg BT 278.35 734.10 Td (a ) Tj ET Q q 0 0 0 rg BT 284.27 734.10 Td (private ) Tj ET Q q 0 0 0 rg BT 313.51 734.10 Td (biotechnology ) Tj ET Q q 0 0 0 rg BT 372.20 734.10 Td (company ) Tj ET Q q 0 0 0 rg BT 410.34 734.10 Td (focused ) Tj ET Q q 0 0 0 rg BT 442.91 734.10 Td (on ) Tj ET Q q 0 0 0 rg BT 454.39 734.10 Td (the ) Tj ET Q q 0 0 0 rg BT 468.09 734.10 Td (discovery ) Tj ET Q q 0 0 0 rg BT 508.45 734.10 Td (and ) Tj ET Q q 0 0 0 rg BT 524.36 734.10 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 722.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.24 722.10 Td (novel ) Tj ET Q q 0 0 0 rg BT 70.37 722.10 Td (anti-cancer ) Tj ET Q q 0 0 0 rg BT 116.69 722.10 Td (therapeutics. ) Tj ET Q q 0 0 0 rg BT 169.27 722.10 Td (The ) Tj ET Q q 0 0 0 rg BT 186.73 722.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 232.53 722.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 269.99 722.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 293.02 722.10 Td (with ) Tj ET Q q 0 0 0 rg BT 312.71 722.10 Td (full ) Tj ET Q q 0 0 0 rg BT 328.51 722.10 Td (rights ) Tj ET Q q 0 0 0 rg BT 353.20 722.10 Td (to ) Tj ET Q q 0 0 0 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417.50 Td (to ) Tj ET Q q 0 0 0 rg BT 519.26 417.50 Td (SK ) Tj ET Q q 0 0 0 rg BT 534.85 417.50 Td (Biotek ) Tj ET Q q 0 0 0 rg BT 564.33 417.50 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.50 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 96.50 405.50 Td ($165 ) Tj ET Q q 0 0 0 rg BT 119.24 405.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 148.13 405.50 Td (, ) Tj ET Q q 0 0 0 rg BT 153.38 405.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 184.44 405.50 Td (to ) Tj ET Q q 0 0 0 rg BT 194.96 405.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 224.91 405.50 Td (adjustments. ) Tj ET Q q 0 0 0 rg BT 277.92 405.50 Td (Initial ) Tj ET Q q 0 0 0 rg BT 304.54 405.50 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 342.82 405.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.90 405.50 Td ($158 ) Tj ET Q q 0 0 0 rg BT 376.64 405.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.53 405.50 Td ( ) Tj ET Q q 0 0 0 rg BT 408.27 405.50 Td (were ) Tj ET Q q 0 0 0 rg BT 430.44 405.50 Td (received ) Tj ET Q q 0 0 0 rg BT 467.04 405.50 Td (in ) Tj ET Q q 0 0 0 rg BT 477.56 405.50 Td (the ) Tj ET Q q 0 0 0 rg BT 492.52 405.50 Td (first ) Tj ET Q q 0 0 0 rg BT 511.37 405.50 Td (quarter ) Tj ET Q q 0 0 0 rg BT 542.43 405.50 Td (of ) Tj ET Q q 0 0 0 rg BT 553.50 405.50 Td (2018. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 393.50 Td (The ) Tj ET Q q 0 0 0 rg BT 53.64 393.50 Td (transaction ) Tj ET Q q 0 0 0 rg BT 99.60 393.50 Td (was ) Tj ET Q q 0 0 0 rg BT 117.24 393.50 Td (accounted ) Tj ET Q q 0 0 0 rg BT 159.87 393.50 Td (for ) Tj ET Q q 0 0 0 rg BT 173.62 393.50 Td (as ) Tj ET Q q 0 0 0 rg BT 184.04 393.50 Td (the ) Tj ET Q q 0 0 0 rg BT 198.35 393.50 Td (sale ) Tj ET Q q 0 0 0 rg BT 215.99 393.50 Td (of ) Tj ET Q q 0 0 0 rg BT 226.41 393.50 Td (a ) Tj ET Q q 0 0 0 rg BT 232.94 393.50 Td (business. ) Tj ET Q q 0 0 0 rg BT 271.27 393.50 Td (The ) Tj ET Q q 0 0 0 rg BT 288.91 393.50 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 333.21 393.50 Td (includes ) Tj ET Q q 0 0 0 rg BT 368.63 393.50 Td (the ) Tj ET Q q 0 0 0 rg BT 382.94 393.50 Td (transfer ) Tj ET Q q 0 0 0 rg BT 415.56 393.50 Td (of ) Tj ET Q q 0 0 0 rg BT 425.99 393.50 Td (the ) Tj ET Q q 0 0 0 rg BT 440.29 393.50 Td (facility) Tj ET Q q 0 0 0 rg BT 467.96 393.50 Td (, ) Tj ET Q q 0 0 0 rg BT 472.56 393.50 Td (the ) Tj ET Q q 0 0 0 rg BT 486.86 393.50 Td (majority ) Tj ET Q q 0 0 0 rg BT 522.84 393.50 Td (of ) Tj ET Q q 0 0 0 rg BT 533.26 393.50 Td (employees ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 381.50 Td (at ) Tj ET Q q 0 0 0 rg BT 45.43 381.50 Td (the ) Tj ET Q q 0 0 0 rg BT 59.86 381.50 Td (site, ) Tj ET Q q 0 0 0 rg BT 78.46 381.50 Td (inventories ) Tj ET Q q 0 0 0 rg BT 125.10 381.50 Td (and ) Tj ET Q q 0 0 0 rg BT 141.75 381.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 171.17 381.50 Td (third-party ) Tj ET Q q 0 0 0 rg BT 216.14 381.50 Td (contract ) Tj ET Q q 0 0 0 rg BT 250.56 381.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 311.08 381.50 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 360.07 381.50 Td (The ) Tj ET Q q 0 0 0 rg BT 377.83 381.50 Td (assets ) Tj ET Q q 0 0 0 rg BT 403.37 381.50 Td (were ) Tj ET Q q 0 0 0 rg BT 425.02 381.50 Td (reduced ) Tj ET Q q 0 0 0 rg BT 458.87 381.50 Td (to ) Tj ET Q q 0 0 0 rg BT 468.86 381.50 Td (their ) Tj ET Q q 0 0 0 rg BT 489.40 381.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 529.93 381.50 Td (relative ) Tj ET Q q 0 0 0 rg BT 562.12 381.50 Td (fair ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 369.50 Td (value ) Tj ET Q q 0 0 0 rg BT 60.17 369.50 Td (after ) Tj ET Q q 0 0 0 rg BT 81.00 369.50 Td (considering ) Tj ET Q q 0 0 0 rg BT 130.17 369.50 Td (the ) Tj ET Q q 0 0 0 rg BT 144.91 369.50 Td (purchase ) Tj ET Q q 0 0 0 rg BT 182.96 369.50 Td (price ) Tj ET Q q 0 0 0 rg BT 205.46 369.50 Td (resulting ) Tj ET Q q 0 0 0 rg BT 242.97 369.50 Td (in ) Tj ET Q q 0 0 0 rg BT 253.27 369.50 Td (an ) Tj ET Q q 0 0 0 rg BT 265.22 369.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 313.84 369.50 Td (char) Tj ET Q q 0 0 0 rg BT 330.86 369.50 Td (ge ) Tj ET Q q 0 0 0 rg BT 342.82 369.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.66 369.50 Td ($146 ) Tj ET Q q 0 0 0 rg BT 376.18 369.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.07 369.50 Td ( ) Tj ET Q q 0 0 0 rg BT 407.59 369.50 Td (that ) Tj ET Q q 0 0 0 rg BT 425.10 369.50 Td (was ) Tj ET Q q 0 0 0 rg BT 443.17 369.50 Td (included ) Tj ET Q q 0 0 0 rg BT 480.12 369.50 Td (in ) Tj ET Q q 0 0 0 rg BT 490.41 369.50 Td (cost ) Tj ET Q q 0 0 0 rg BT 509.04 369.50 Td (of ) Tj ET Q q 0 0 0 rg BT 519.88 369.50 Td (products ) Tj ET Q q 0 0 0 rg BT 556.84 369.50 Td (sold. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 357.50 Td (SK ) Tj ET Q q 0 0 0 rg BT 51.28 357.50 Td (Biotek ) Tj ET Q q 0 0 0 rg BT 80.45 357.50 Td (will ) Tj ET Q q 0 0 0 rg BT 98.50 357.50 Td (provide ) Tj ET Q q 0 0 0 rg BT 131.55 357.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 161.25 357.50 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 222.06 357.50 Td (services ) Tj ET Q q 0 0 0 rg BT 256.77 357.50 Td (for ) Tj ET Q q 0 0 0 rg BT 270.93 357.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 294.55 357.50 Td (through ) Tj ET Q q 0 0 0 rg BT 328.16 357.50 Td (2022.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 332.1669921875 m 99.96484375 332.1669921875 l s q 0 0 0 rg BT 36.00 333.50 Td (V) Tj ET Q q 0 0 0 rg BT 41.37 333.50 Td (iiV) Tj ET Q q 0 0 0 rg BT 52.85 333.50 Td ( ) Tj ET Q q 0 0 0 rg BT 55.35 333.50 Td (Healthcar) Tj ET Q q 0 0 0 rg BT 95.53 333.50 Td (e) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 318.50 Td (In ) Tj ET Q q 0 0 0 rg BT 46.64 318.50 Td (2016, ) Tj ET Q q 0 0 0 rg BT 71.46 318.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.90 318.50 Td (sold ) Tj ET Q q 0 0 0 rg BT 113.88 318.50 Td (its ) Tj ET Q q 0 0 0 rg BT 125.64 318.50 Td (investigational ) Tj ET Q q 0 0 0 rg BT 186.83 318.50 Td (HIV) Tj ET Q q 0 0 0 rg BT 204.43 318.50 Td ( ) Tj ET Q q 0 0 0 rg BT 206.74 318.50 Td (medicines ) Tj ET Q q 0 0 0 rg BT 249.60 318.50 Td (business ) Tj ET Q q 0 0 0 rg BT 285.80 318.50 Td (consisting ) Tj ET Q q 0 0 0 rg BT 328.68 318.50 Td (of ) Tj ET Q q 0 0 0 rg BT 339.32 318.50 Td (a ) Tj ET Q q 0 0 0 rg BT 346.07 318.50 Td (number ) Tj ET Q q 0 0 0 rg BT 378.93 318.50 Td (of ) Tj ET Q q 0 0 0 rg BT 389.58 318.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 413.56 318.50 Td (programs ) Tj ET Q q 0 0 0 rg BT 453.65 318.50 Td (at ) Tj ET Q q 0 0 0 rg BT 463.18 318.50 Td (dif) Tj ET Q q 0 0 0 rg BT 474.11 318.50 Td (ferent ) Tj ET Q q 0 0 0 rg BT 499.74 318.50 Td (stages ) Tj ET Q q 0 0 0 rg BT 526.49 318.50 Td (of ) Tj ET Q q 0 0 0 rg BT 537.13 318.50 Td (discovery ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 306.50 Td (and ) Tj ET Q q 0 0 0 rg BT 54.31 306.50 Td (development ) Tj ET Q q 0 0 0 rg BT 109.84 306.50 Td (to ) Tj ET Q q 0 0 0 rg BT 121.22 306.50 Td (V) Tj ET Q q 0 0 0 rg BT 127.84 306.50 Td (iiV) Tj ET Q q 0 0 0 rg BT 140.44 306.50 Td ( ) Tj ET Q q 0 0 0 rg BT 144.31 306.50 Td (Healthcare. ) Tj ET Q q 0 0 0 rg BT 193.99 306.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 218.99 306.50 Td (received ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.73 306.50 Td ($350 ) Tj ET Q q 0 0 0 rg BT 280.60 306.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.50 306.50 Td ( ) Tj ET Q q 0 0 0 rg BT 313.37 306.50 Td (and ) Tj ET Q q 0 0 0 rg BT 331.69 306.50 Td (is ) Tj ET Q q 0 0 0 rg BT 342.23 306.50 Td (also ) Tj ET Q q 0 0 0 rg BT 362.22 306.50 Td (entitled ) Tj ET Q q 0 0 0 rg BT 396.08 306.50 Td (to ) Tj ET Q q 0 0 0 rg BT 407.74 306.50 Td (receive ) Tj ET Q q 0 0 0 rg BT 440.48 306.50 Td (from ) Tj ET Q q 0 0 0 rg BT 463.51 306.50 Td (V) Tj ET Q q 0 0 0 rg BT 470.13 306.50 Td (iiV) Tj ET Q q 0 0 0 rg BT 482.73 306.50 Td ( ) Tj ET Q q 0 0 0 rg BT 486.61 306.50 Td (Healthcare ) Tj ET Q q 0 0 0 rg BT 533.79 306.50 Td (contingent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 294.50 Td (development ) Tj ET Q q 0 0 0 rg BT 90.42 294.50 Td (and ) Tj ET Q q 0 0 0 rg BT 107.63 294.50 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 151.49 294.50 Td (milestone ) Tj ET Q q 0 0 0 rg BT 193.14 294.50 Td (payments ) Tj ET Q q 0 0 0 rg BT 234.23 294.50 Td (of ) Tj ET Q q 0 0 0 rg BT 245.33 294.50 Td (up ) Tj ET Q q 0 0 0 rg BT 258.10 294.50 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.65 294.50 Td ($1.1 ) Tj ET Q q 0 0 0 rg BT 288.92 294.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.03 294.50 Td (, ) Tj ET Q q 0 0 0 rg BT 320.30 294.50 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 368.60 294.50 Td (milestone ) Tj ET Q q 0 0 0 rg BT 410.25 294.50 Td (payments ) Tj ET Q q 0 0 0 rg BT 451.35 294.50 Td (of ) Tj ET Q q 0 0 0 rg BT 462.45 294.50 Td (up ) Tj ET Q q 0 0 0 rg BT 475.21 294.50 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.76 294.50 Td ($4.3 ) Tj ET Q q 0 0 0 rg BT 506.03 294.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.14 294.50 Td ( ) Tj ET Q q 0 0 0 rg BT 534.91 294.50 Td (and ) Tj ET Q q 0 0 0 rg BT 552.12 294.50 Td (future ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 282.50 Td (tiered ) Tj ET Q q 0 0 0 rg BT 61.79 282.50 Td (royalties. ) Tj ET Q q 0 0 0 rg BT 101.74 282.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 125.88 282.50 Td (earned ) Tj ET Q q 0 0 0 rg BT 155.55 282.50 Td (transitional ) Tj ET Q q 0 0 0 rg BT 203.56 282.50 Td (fees ) Tj ET Q q 0 0 0 rg BT 222.68 282.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 234.04 282.50 Td ($10 ) Tj ET Q q 0 0 0 rg BT 252.06 282.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 280.95 282.50 Td ( ) Tj ET Q q 0 0 0 rg BT 283.97 282.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.43 282.50 Td ($105 ) Tj ET Q q 0 0 0 rg BT 324.45 282.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.34 282.50 Td ( ) Tj ET Q q 0 0 0 rg BT 356.36 282.50 Td (for ) Tj ET Q q 0 0 0 rg BT 371.05 282.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 401.27 282.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 425.96 282.50 Td (and ) Tj ET Q q 0 0 0 rg BT 443.42 282.50 Td (other ) Tj ET Q q 0 0 0 rg BT 466.99 282.50 Td (services ) Tj ET Q q 0 0 0 rg BT 502.22 282.50 Td (in ) Tj ET Q q 0 0 0 rg BT 513.02 282.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 536.04 282.50 Td (and ) Tj ET Q q 0 0 0 rg BT 553.50 282.50 Td (2016, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 270.50 Td (respectively) Tj ET Q q 0 0 0 rg BT 83.66 270.50 Td (.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 245.1669921875 m 109.7841796875 245.1669921875 l s q 0 0 0 rg BT 36.00 246.50 Td (Other Divestitur) Tj ET Q q 0 0 0 rg BT 101.45 246.50 Td (es) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 231.50 Td (Refer ) Tj ET Q q 0 0 0 rg BT 60.59 231.50 Td (to ) Tj ET Q q 0 0 0 rg BT 70.75 231.50 Td ("—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 106.65 231.50 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 111.65 231.50 Td (. ) Tj ET Q q 0 0 0 rg BT 116.01 231.50 Td (Alliances" ) Tj ET Q q 0 0 0 rg BT 160.23 231.50 Td (for ) Tj ET Q q 0 0 0 rg BT 174.28 231.50 Td (a ) Tj ET Q q 0 0 0 rg BT 181.10 231.50 Td (discussion ) Tj ET Q q 0 0 0 rg BT 225.15 231.50 Td (on ) Tj ET Q q 0 0 0 rg BT 237.53 231.50 Td (the ) Tj ET Q q 0 0 0 rg BT 252.13 231.50 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 296.72 231.50 Td (transactions ) Tj ET Q q 0 0 0 rg BT 346.87 231.50 Td (with ) Tj ET Q q 0 0 0 rg BT 367.03 231.50 Td (Reckitt, ) Tj ET Q q 0 0 0 rg BT 400.79 231.50 Td (Lilly) Tj ET Q q 0 0 0 rg BT 419.59 231.50 Td (, ) Tj ET Q q 0 0 0 rg BT 424.30 231.50 Td (The ) Tj ET Q q 0 0 0 rg BT 442.22 231.50 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 486.26 231.50 Td (Company) Tj ET Q q 0 0 0 rg BT 524.50 231.50 Td (, ) Tj ET Q q 0 0 0 rg BT 529.21 231.50 Td (V) Tj ET Q q 0 0 0 rg BT 535.32 231.50 Td (aleant ) Tj ET Q q 0 0 0 rg BT 561.58 231.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 219.50 Td (AstraZeneca. ) Tj ET Q q 0 0 0 rg BT 90.96 219.50 Td (Revenues ) Tj ET Q q 0 0 0 rg BT 131.78 219.50 Td (and ) Tj ET Q q 0 0 0 rg BT 148.16 219.50 Td (pretax ) Tj ET Q q 0 0 0 rg BT 175.08 219.50 Td (earnings ) Tj ET Q q 0 0 0 rg BT 210.90 219.50 Td (related ) Tj ET Q q 0 0 0 rg BT 240.04 219.50 Td (to ) Tj ET Q q 0 0 0 rg BT 249.76 219.50 Td (all ) Tj ET Q q 0 0 0 rg BT 261.70 219.50 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 309.74 219.50 Td (were ) Tj ET Q q 0 0 0 rg BT 331.11 219.50 Td (not ) Tj ET Q q 0 0 0 rg BT 345.83 219.50 Td (material ) Tj ET Q q 0 0 0 rg BT 380.52 219.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.24 219.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.24 219.50 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.68 219.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.68 219.50 Td ( ) Tj ET Q q 0 0 0 rg BT 436.62 219.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.00 219.50 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.00 219.50 Td ( ) Tj ET Q q 0 0 0 rg BT 474.94 219.50 Td (\(excluding ) Tj ET Q q 0 0 0 rg BT 519.64 219.50 Td (the ) Tj ET Q q 0 0 0 rg BT 533.80 219.50 Td (divestiture ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 207.50 Td (gains ) Tj ET Q q 0 0 0 rg BT 59.61 207.50 Td (and ) Tj ET Q q 0 0 0 rg BT 76.55 207.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 125.15 207.50 Td (char) Tj ET Q q 0 0 0 rg BT 142.17 207.50 Td (ges\).) Tj ET Q BT /F4 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 181.93505859375 m 124.056640625 181.93505859375 l s q 0 0 0 rg BT 36.00 183.50 Td (Assets ) Tj ET Q q 0 0 0 rg BT 64.06 183.50 Td (Held-For-Sale) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 168.50 Td (In ) Tj ET Q q 0 0 0 rg BT 46.67 168.50 Td (2017, ) Tj ET Q q 0 0 0 rg BT 71.51 168.50 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.97 168.50 Td (agreed ) Tj ET Q q 0 0 0 rg BT 123.95 168.50 Td (to ) Tj ET Q q 0 0 0 rg BT 134.07 168.50 Td (sell ) Tj ET Q q 0 0 0 rg BT 150.30 168.50 Td (a ) Tj ET Q q 0 0 0 rg BT 157.07 168.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 181.08 168.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 211.74 168.50 Td (in ) Tj ET Q q 0 0 0 rg BT 221.69 168.50 Td (W) Tj ET Q q 0 0 0 rg BT 230.33 168.50 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 274.60 168.50 Td (Connecticut. ) Tj ET Q q 0 0 0 rg BT 327.59 168.50 Td (The ) Tj ET Q q 0 0 0 rg BT 345.48 168.50 Td (transaction ) Tj ET Q q 0 0 0 rg BT 391.69 168.50 Td (is ) Tj ET Q q 0 0 0 rg BT 400.70 168.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 438.57 168.50 Td (to ) Tj ET Q q 0 0 0 rg BT 448.68 168.50 Td (close ) Tj ET Q q 0 0 0 rg BT 471.57 168.50 Td (in ) Tj ET Q q 0 0 0 rg BT 481.69 168.50 Td (the ) Tj ET Q q 0 0 0 rg BT 496.24 168.50 Td (first ) Tj ET Q q 0 0 0 rg BT 514.69 168.50 Td (quarter ) Tj ET Q q 0 0 0 rg BT 545.34 168.50 Td (of ) Tj ET Q q 0 0 0 rg BT 556.01 168.50 Td (2018 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 156.50 Td (and ) Tj ET Q q 0 0 0 rg BT 52.94 156.50 Td (will ) Tj ET Q q 0 0 0 rg BT 71.00 156.50 Td (be ) Tj ET Q q 0 0 0 rg BT 82.94 156.50 Td (accounted ) Tj ET Q q 0 0 0 rg BT 125.97 156.50 Td (for ) Tj ET Q q 0 0 0 rg BT 140.13 156.50 Td (as ) Tj ET Q q 0 0 0 rg BT 150.96 156.50 Td (a ) Tj ET Q q 0 0 0 rg BT 157.90 156.50 Td (sale ) Tj ET Q q 0 0 0 rg BT 175.95 156.50 Td (of ) Tj ET Q q 0 0 0 rg BT 186.78 156.50 Td (an ) Tj ET Q q 0 0 0 rg BT 198.72 156.50 Td (asset. ) Tj ET Q q 0 0 0 rg BT 222.98 156.50 Td (The ) Tj ET Q q 0 0 0 rg BT 241.03 156.50 Td (asset ) Tj ET Q q 0 0 0 rg BT 262.97 156.50 Td (was ) Tj ET Q q 0 0 0 rg BT 281.02 156.50 Td (accounted ) Tj ET Q q 0 0 0 rg BT 324.06 156.50 Td (for ) Tj ET Q q 0 0 0 rg BT 338.22 156.50 Td (as ) Tj ET Q q 0 0 0 rg BT 349.05 156.50 Td (held-for) Tj ET Q q 0 0 0 rg BT 381.06 156.50 Td (-sale ) Tj ET Q q 0 0 0 rg BT 402.44 156.50 Td (as ) Tj ET Q q 0 0 0 rg BT 413.27 156.50 Td (of ) Tj ET Q q 0 0 0 rg BT 424.10 156.50 Td (December ) Tj ET Q q 0 0 0 rg BT 467.69 156.50 Td (31, ) Tj ET Q q 0 0 0 rg BT 482.69 156.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 505.19 156.50 Td (and ) Tj ET Q q 0 0 0 rg BT 522.13 156.50 Td (reduced ) Tj ET Q q 0 0 0 rg BT 556.28 156.50 Td (to ) Tj ET Q q 0 0 0 rg BT 566.56 156.50 Td (its ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 144.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 76.82 144.50 Td (relative ) Tj ET Q q 0 0 0 rg BT 109.30 144.50 Td (fair ) Tj ET Q q 0 0 0 rg BT 125.68 144.50 Td (value ) Tj ET Q q 0 0 0 rg BT 149.83 144.50 Td (resulting ) Tj ET Q q 0 0 0 rg BT 187.33 144.50 Td (in ) Tj ET Q q 0 0 0 rg BT 197.61 144.50 Td (an ) Tj ET Q q 0 0 0 rg BT 209.54 144.50 Td (impairment ) Tj ET Q q 0 0 0 rg BT 258.14 144.50 Td (char) Tj ET Q q 0 0 0 rg BT 275.17 144.50 Td (ge ) Tj ET Q q 0 0 0 rg BT 287.11 144.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 297.94 144.50 Td ($79 ) Tj ET Q q 0 0 0 rg BT 315.44 144.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.33 144.50 Td ( ) Tj ET Q q 0 0 0 rg BT 346.83 144.50 Td (that ) Tj ET Q q 0 0 0 rg BT 364.33 144.50 Td (was ) Tj ET Q q 0 0 0 rg BT 382.38 144.50 Td (included ) Tj ET Q q 0 0 0 rg BT 419.31 144.50 Td (in ) Tj ET Q q 0 0 0 rg BT 429.59 144.50 Td (R&D ) Tj ET Q q 0 0 0 rg BT 453.76 144.50 Td (expense.) Tj ET Q endstream endobj 157 0 obj <> endobj 158 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (78) Tj ET Q BT /F4 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 747.68505859375 m 137.5869140625 747.68505859375 l s q 0 0 0 rg BT 36.00 749.25 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 78.69 749.25 Td (Arrangements) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 729.9169921875 m 75.990234375 729.9169921875 l s q 0 0 0 rg BT 36.00 731.25 Td (Halozyme) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 716.25 Td (In ) Tj ET Q q 0 0 0 rg BT 47.13 716.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 72.44 716.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 96.36 716.25 Td (and ) Tj ET Q q 0 0 0 rg BT 113.60 716.25 Td (Halozyme ) Tj ET Q q 0 0 0 rg BT 157.50 716.25 Td (entered ) Tj ET Q q 0 0 0 rg BT 189.73 716.25 Td (into ) Tj ET Q q 0 0 0 rg BT 208.08 716.25 Td (a ) Tj ET Q q 0 0 0 rg BT 215.33 716.25 Td (global ) Tj ET Q q 0 0 0 rg BT 243.12 716.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 298.69 716.25 Td (and ) Tj ET Q q 0 0 0 rg BT 315.93 716.25 Td (license ) Tj ET Q q 0 0 0 rg BT 346.49 716.25 Td (agreement ) Tj ET Q q 0 0 0 rg BT 390.94 716.25 Td (to ) Tj ET Q q 0 0 0 rg BT 401.52 716.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 435.98 716.25 Td (subcutaneously ) Tj ET Q q 0 0 0 rg BT 500.43 716.25 Td (administered ) Tj ET Q q 0 0 0 rg BT 554.89 716.25 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 704.25 Td (IO ) Tj ET Q q 0 0 0 rg BT 50.01 704.25 Td (medicines ) Tj ET Q q 0 0 0 rg BT 94.00 704.25 Td (using ) Tj ET Q q 0 0 0 rg BT 119.12 704.25 Td (Halozyme's ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 169.37 704.25 Td (ENHANZE) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.81 704.25 Td (* ) Tj ET Q q 0 0 0 rg BT 222.27 704.25 Td (drug-delivery ) Tj ET Q q 0 0 0 rg BT 280.14 704.25 Td (technology) Tj ET Q q 0 0 0 rg BT 323.93 704.25 Td (. ) Tj ET Q q 0 0 0 rg BT 329.63 704.25 Td (This ) Tj ET Q q 0 0 0 rg BT 350.86 704.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 398.75 704.25 Td (may ) Tj ET Q q 0 0 0 rg BT 419.42 704.25 Td (allow ) Tj ET Q q 0 0 0 rg BT 445.09 704.25 Td (for ) Tj ET Q q 0 0 0 rg BT 460.21 704.25 Td (more ) Tj ET Q q 0 0 0 rg BT 484.21 704.25 Td (rapid ) Tj ET Q q 0 0 0 rg BT 508.21 704.25 Td (delivery ) Tj ET Q q 0 0 0 rg BT 544.42 704.25 Td (of ) Tj ET Q q 0 0 0 rg BT 556.21 704.25 Td (lar) Tj ET Q q 0 0 0 rg BT 566.57 704.25 Td (ge ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 692.25 Td (volume ) Tj ET Q q 0 0 0 rg BT 68.41 692.25 Td (injectable ) Tj ET Q q 0 0 0 rg BT 109.69 692.25 Td (medications ) Tj ET Q q 0 0 0 rg BT 160.43 692.25 Td (through ) Tj ET Q q 0 0 0 rg BT 193.95 692.25 Td (subcutaneous ) Tj ET Q q 0 0 0 rg BT 250.24 692.25 Td (delivery) Tj ET Q q 0 0 0 rg BT 282.35 692.25 Td (. ) Tj ET Q q 0 0 0 rg BT 287.27 692.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 310.81 692.25 Td (paid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 330.44 692.25 Td ($105 ) Tj ET Q q 0 0 0 rg BT 352.85 692.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.74 692.25 Td ( ) Tj ET Q q 0 0 0 rg BT 384.16 692.25 Td (to ) Tj ET Q q 0 0 0 rg BT 394.35 692.25 Td (Halozyme ) Tj ET Q q 0 0 0 rg BT 437.86 692.25 Td (for ) Tj ET Q q 0 0 0 rg BT 451.94 692.25 Td (access ) Tj ET Q q 0 0 0 rg BT 479.89 692.25 Td (to ) Tj ET Q q 0 0 0 rg BT 490.08 692.25 Td (the ) Tj ET Q q 0 0 0 rg BT 504.71 692.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 551.56 692.25 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 680.25 Td (was ) Tj ET Q q 0 0 0 rg BT 54.11 680.25 Td (included ) Tj ET Q q 0 0 0 rg BT 91.11 680.25 Td (in ) Tj ET Q q 0 0 0 rg BT 101.45 680.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 125.68 680.25 Td (expense. ) Tj ET Q q 0 0 0 rg BT 162.95 680.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 186.63 680.25 Td (designated ) Tj ET Q q 0 0 0 rg BT 231.95 680.25 Td (multiple ) Tj ET Q q 0 0 0 rg BT 267.85 680.25 Td (IO ) Tj ET Q q 0 0 0 rg BT 280.96 680.25 Td (tar) Tj ET Q q 0 0 0 rg BT 291.32 680.25 Td (gets, ) Tj ET Q q 0 0 0 rg BT 312.49 680.25 Td (including ) Tj ET Q q 0 0 0 rg BT 352.83 680.25 Td (PD-1, ) Tj ET Q q 0 0 0 rg BT 379.00 680.25 Td (to ) Tj ET Q q 0 0 0 rg BT 389.34 680.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 423.56 680.25 Td (using ) Tj ET Q q 0 0 0 rg BT 447.79 680.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 462.57 680.25 Td (ENHANZE) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.02 680.25 Td (* ) Tj ET Q q 0 0 0 rg BT 514.58 680.25 Td (technology ) Tj ET Q q 0 0 0 rg BT 561.57 680.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 668.25 Td (has ) Tj ET Q q 0 0 0 rg BT 51.63 668.25 Td (an ) Tj ET Q q 0 0 0 rg BT 63.36 668.25 Td (option ) Tj ET Q q 0 0 0 rg BT 91.21 668.25 Td (to ) Tj ET Q q 0 0 0 rg BT 101.28 668.25 Td (select ) Tj ET Q q 0 0 0 rg BT 126.34 668.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 168.63 668.25 Td (tar) Tj ET Q q 0 0 0 rg BT 178.99 668.25 Td (gets ) Tj ET Q q 0 0 0 rg BT 197.40 668.25 Td (within ) Tj ET Q q 0 0 0 rg BT 225.25 668.25 Td (five ) Tj ET Q q 0 0 0 rg BT 243.09 668.25 Td (years ) Tj ET Q q 0 0 0 rg BT 266.48 668.25 Td (from ) Tj ET Q q 0 0 0 rg BT 288.22 668.25 Td (the ) Tj ET Q q 0 0 0 rg BT 302.73 668.25 Td (ef) Tj ET Q q 0 0 0 rg BT 310.32 668.25 Td (fective ) Tj ET Q q 0 0 0 rg BT 339.81 668.25 Td (date ) Tj ET Q q 0 0 0 rg BT 358.76 668.25 Td (up ) Tj ET Q q 0 0 0 rg BT 371.06 668.25 Td (to ) Tj ET Q q 0 0 0 rg BT 381.13 668.25 Td (a ) Tj ET Q q 0 0 0 rg BT 387.87 668.25 Td (maximum ) Tj ET Q q 0 0 0 rg BT 430.71 668.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.34 668.25 Td (1) Tj ET Q q 0 0 0 rg BT 445.97 668.25 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.97 668.25 Td ( ) Tj ET Q q 0 0 0 rg BT 453.26 668.25 Td (tar) Tj ET Q q 0 0 0 rg BT 463.63 668.25 Td (gets. ) Tj ET Q q 0 0 0 rg BT 484.53 668.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 507.95 668.25 Td (may ) Tj ET Q q 0 0 0 rg BT 527.46 668.25 Td (pay ) Tj ET Q q 0 0 0 rg BT 544.19 668.25 Td (up ) Tj ET Q q 0 0 0 rg BT 556.49 668.25 Td (to ) Tj ET Q q 0 0 0 rg BT 566.56 668.25 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 656.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 77.29 656.25 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 78.59 656.25 Td ($160 ) Tj ET Q q 0 0 0 rg BT 99.89 656.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 128.79 656.25 Td ( ) Tj ET Q q 0 0 0 rg BT 130.09 656.25 Td (in ) Tj ET Q q 0 0 0 rg BT 139.17 656.25 Td (achieved ) Tj ET Q q 0 0 0 rg BT 176.00 656.25 Td (contingent ) Tj ET Q q 0 0 0 rg BT 219.51 656.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 274.96 656.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 317.36 656.25 Td (and ) Tj ET Q q 0 0 0 rg BT 333.10 656.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 379.94 656.25 Td (milestones ) Tj ET Q q 0 0 0 rg BT 424.01 656.25 Td (for ) Tj ET Q q 0 0 0 rg BT 436.97 656.25 Td (each ) Tj ET Q q 0 0 0 rg BT 456.59 656.25 Td (of ) Tj ET Q q 0 0 0 rg BT 466.22 656.25 Td (the ) Tj ET Q q 0 0 0 rg BT 479.74 656.25 Td (nominated ) Tj ET Q q 0 0 0 rg BT 523.25 656.25 Td (collaboration ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 644.25 Td (tar) Tj ET Q q 0 0 0 rg BT 46.37 644.25 Td (gets, ) Tj ET Q q 0 0 0 rg BT 66.34 644.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 107.69 644.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 147.93 644.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 187.62 644.25 Td (for ) Tj ET Q q 0 0 0 rg BT 200.64 644.25 Td (combination ) Tj ET Q q 0 0 0 rg BT 252.00 644.25 Td (products ) Tj ET Q q 0 0 0 rg BT 287.80 644.25 Td (and ) Tj ET Q q 0 0 0 rg BT 303.60 644.25 Td (future ) Tj ET Q q 0 0 0 rg BT 328.84 644.25 Td (royalties ) Tj ET Q q 0 0 0 rg BT 364.63 644.25 Td (on ) Tj ET Q q 0 0 0 rg BT 376.00 644.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 396.80 644.25 Td (of ) Tj ET Q q 0 0 0 rg BT 406.49 644.25 Td (products ) Tj ET Q q 0 0 0 rg BT 442.29 644.25 Td (using ) Tj ET Q q 0 0 0 rg BT 465.32 644.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 478.90 644.25 Td (ENHANZE) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.35 644.25 Td (* ) Tj ET Q q 0 0 0 rg BT 529.71 644.25 Td (technology) Tj ET Q q 0 0 0 rg BT 573.50 644.25 Td (.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 624.9169921875 m 68.216796875 624.9169921875 l s q 0 0 0 rg BT 36.00 626.25 Td (CytomX) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 611.25 Td (In ) Tj ET Q q 0 0 0 rg BT 45.71 611.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 69.59 611.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 92.09 611.25 Td (expanded ) Tj ET Q q 0 0 0 rg BT 131.78 611.25 Td (its ) Tj ET Q q 0 0 0 rg BT 142.61 611.25 Td (strategic ) Tj ET Q q 0 0 0 rg BT 177.86 611.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 232.00 611.25 Td (with ) Tj ET Q q 0 0 0 rg BT 251.15 611.25 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 286.98 611.25 Td (to ) Tj ET Q q 0 0 0 rg BT 296.14 611.25 Td (discover ) Tj ET Q q 0 0 0 rg BT 331.39 611.25 Td (novel ) Tj ET Q q 0 0 0 rg BT 354.99 611.25 Td (therapies ) Tj ET Q q 0 0 0 rg BT 392.46 611.25 Td (using ) Tj ET Q q 0 0 0 rg BT 415.51 611.25 Td (CytomX’) Tj ET Q q 0 0 0 rg BT 452.73 611.25 Td (s ) Tj ET Q q 0 0 0 rg BT 458.00 611.25 Td (proprietary ) Tj ET Q q 0 0 0 rg BT 503.81 611.25 Td (Probody ) Tj ET Q q 0 0 0 rg BT 539.08 611.25 Td (platform. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 599.25 Td (As ) Tj ET Q q 0 0 0 rg BT 48.78 599.25 Td (part ) Tj ET Q q 0 0 0 rg BT 65.99 599.25 Td (of ) Tj ET Q q 0 0 0 rg BT 75.99 599.25 Td (the ) Tj ET Q q 0 0 0 rg BT 89.87 599.25 Td (original ) Tj ET Q q 0 0 0 rg BT 122.64 599.25 Td (May ) Tj ET Q q 0 0 0 rg BT 142.64 599.25 Td (2014 ) Tj ET Q q 0 0 0 rg BT 164.31 599.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 218.73 599.25 Td (to ) Tj ET Q q 0 0 0 rg BT 228.18 599.25 Td (discover) Tj ET Q q 0 0 0 rg BT 261.65 599.25 Td (, ) Tj ET Q q 0 0 0 rg BT 265.82 599.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 299.14 599.25 Td (and ) Tj ET Q q 0 0 0 rg BT 315.25 599.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 375.77 599.25 Td (Probody ) Tj ET Q q 0 0 0 rg BT 411.32 599.25 Td (therapeutics, ) Tj ET Q q 0 0 0 rg BT 463.80 599.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 486.59 599.25 Td (selected ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.46 599.25 Td (four) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 537.12 599.25 Td ( ) Tj ET Q q 0 0 0 rg BT 538.79 599.25 Td (oncology ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 587.25 Td (tar) Tj ET Q q 0 0 0 rg BT 46.37 587.25 Td (gets, ) Tj ET Q q 0 0 0 rg BT 68.48 587.25 Td (including ) Tj ET Q q 0 0 0 rg BT 109.76 587.25 Td (CTLA-4. ) Tj ET Q q 0 0 0 rg BT 150.21 587.25 Td (Pursuant ) Tj ET Q q 0 0 0 rg BT 188.72 587.25 Td (to ) Tj ET Q q 0 0 0 rg BT 200.01 587.25 Td (the ) Tj ET Q q 0 0 0 rg BT 215.73 587.25 Td (expanded ) Tj ET Q q 0 0 0 rg BT 257.56 587.25 Td (agreement, ) Tj ET Q q 0 0 0 rg BT 305.20 587.25 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 343.16 587.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 376.65 587.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 401.29 587.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 442.56 587.25 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 488.83 587.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 515.12 587.25 Td (to ) Tj ET Q q 0 0 0 rg BT 526.41 587.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 561.57 587.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 575.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 97.71 575.25 Td (Probody ) Tj ET Q q 0 0 0 rg BT 134.47 575.25 Td (therapeutics ) Tj ET Q q 0 0 0 rg BT 185.64 575.25 Td (for ) Tj ET Q q 0 0 0 rg BT 200.16 575.25 Td (up ) Tj ET Q q 0 0 0 rg BT 213.02 575.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.66 575.25 Td (eight) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 243.66 575.25 Td ( ) Tj ET Q q 0 0 0 rg BT 246.52 575.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 289.37 575.25 Td (tar) Tj ET Q q 0 0 0 rg BT 299.74 575.25 Td (gets. ) Tj ET Q q 0 0 0 rg BT 321.21 575.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 345.19 575.25 Td (paid ) Tj ET Q q 0 0 0 rg BT 365.27 575.25 Td (CytomX ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.58 575.25 Td ($75 ) Tj ET Q q 0 0 0 rg BT 420.44 575.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 449.33 575.25 Td ( ) Tj ET Q q 0 0 0 rg BT 452.19 575.25 Td (for ) Tj ET Q q 0 0 0 rg BT 466.71 575.25 Td (the ) Tj ET Q q 0 0 0 rg BT 481.79 575.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 507.43 575.25 Td (to ) Tj ET Q q 0 0 0 rg BT 518.07 575.25 Td (the ) Tj ET Q q 0 0 0 rg BT 533.15 575.25 Td (initial ) Tj ET Q q 0 0 0 rg BT 559.34 575.25 Td (four ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 563.25 Td (tar) Tj ET Q q 0 0 0 rg BT 46.37 563.25 Td (gets ) Tj ET Q q 0 0 0 rg BT 65.36 563.25 Td (which ) Tj ET Q q 0 0 0 rg BT 92.69 563.25 Td (was ) Tj ET Q q 0 0 0 rg BT 111.13 563.25 Td (expensed ) Tj ET Q q 0 0 0 rg BT 151.22 563.25 Td (as ) Tj ET Q q 0 0 0 rg BT 162.44 563.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 187.00 563.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 209.32 563.25 Td (to ) Tj ET Q q 0 0 0 rg BT 219.99 563.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 245.37 563.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 269.38 563.25 Td (paid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 289.49 563.25 Td ($200 ) Tj ET Q q 0 0 0 rg BT 312.38 563.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 341.27 563.25 Td ( ) Tj ET Q q 0 0 0 rg BT 344.15 563.25 Td (to ) Tj ET Q q 0 0 0 rg BT 354.82 563.25 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 392.15 563.25 Td (for ) Tj ET Q q 0 0 0 rg BT 406.70 563.25 Td (access ) Tj ET Q q 0 0 0 rg BT 435.13 563.25 Td (to ) Tj ET Q q 0 0 0 rg BT 445.79 563.25 Td (the ) Tj ET Q q 0 0 0 rg BT 460.90 563.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 503.77 563.25 Td (tar) Tj ET Q q 0 0 0 rg BT 514.14 563.25 Td (gets ) Tj ET Q q 0 0 0 rg BT 533.14 563.25 Td (which ) Tj ET Q q 0 0 0 rg BT 560.46 563.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 551.25 Td (included ) Tj ET Q q 0 0 0 rg BT 74.07 551.25 Td (in ) Tj ET Q q 0 0 0 rg BT 85.48 551.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 110.78 551.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 146.62 551.25 Td (in ) Tj ET Q q 0 0 0 rg BT 158.03 551.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 184.16 551.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 208.92 551.25 Td (will ) Tj ET Q q 0 0 0 rg BT 228.11 551.25 Td (also ) Tj ET Q q 0 0 0 rg BT 247.85 551.25 Td (reimburse ) Tj ET Q q 0 0 0 rg BT 291.47 551.25 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 329.55 551.25 Td (for ) Tj ET Q q 0 0 0 rg BT 344.84 551.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 375.68 551.25 Td (research ) Tj ET Q q 0 0 0 rg BT 412.62 551.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 436.25 551.25 Td (over ) Tj ET Q q 0 0 0 rg BT 457.65 551.25 Td (the ) Tj ET Q q 0 0 0 rg BT 473.50 551.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 529.89 551.25 Td (period, ) Tj ET Q q 0 0 0 rg BT 561.57 551.25 Td (pay ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 539.25 Td (contingent ) Tj ET Q q 0 0 0 rg BT 81.06 539.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 138.05 539.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 181.99 539.25 Td (and ) Tj ET Q q 0 0 0 rg BT 199.27 539.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 221.55 539.25 Td (based ) Tj ET Q q 0 0 0 rg BT 247.17 539.25 Td (milestones ) Tj ET Q q 0 0 0 rg BT 292.78 539.25 Td (up ) Tj ET Q q 0 0 0 rg BT 305.63 539.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 316.25 539.25 Td ($448 ) Tj ET Q q 0 0 0 rg BT 339.10 539.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.99 539.25 Td ( ) Tj ET Q q 0 0 0 rg BT 370.83 539.25 Td (if ) Tj ET Q q 0 0 0 rg BT 379.78 539.25 Td (achieved ) Tj ET Q q 0 0 0 rg BT 418.16 539.25 Td (for ) Tj ET Q q 0 0 0 rg BT 432.67 539.25 Td (each ) Tj ET Q q 0 0 0 rg BT 453.82 539.25 Td (collaboration ) Tj ET Q q 0 0 0 rg BT 509.43 539.25 Td (tar) Tj ET Q q 0 0 0 rg BT 519.79 539.25 Td (get ) Tj ET Q q 0 0 0 rg BT 534.85 539.25 Td (and ) Tj ET Q q 0 0 0 rg BT 552.14 539.25 Td (future ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 527.25 Td (royalties.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 507.9169921875 m 64.3251953125 507.9169921875 l s q 0 0 0 rg BT 36.00 509.25 Td (Biogen) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 494.25 Td (In ) Tj ET Q q 0 0 0 rg BT 45.72 494.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 69.61 494.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 92.12 494.25 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 142.38 494.25 Td (to ) Tj ET Q q 0 0 0 rg BT 151.54 494.25 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 181.82 494.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 220.97 494.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 245.14 494.25 Td (to ) Tj ET Q q 0 0 0 rg BT 254.30 494.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 287.35 494.25 Td (and ) Tj ET Q q 0 0 0 rg BT 303.17 494.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 363.42 494.25 Td (BMS-986168, ) Tj ET Q q 0 0 0 rg BT 421.76 494.25 Td (an ) Tj ET Q q 0 0 0 rg BT 432.58 494.25 Td (anti-eT) Tj ET Q q 0 0 0 rg BT 460.76 494.25 Td (au ) Tj ET Q q 0 0 0 rg BT 471.58 494.25 Td (compound ) Tj ET Q q 0 0 0 rg BT 515.19 494.25 Td (in ) Tj ET Q q 0 0 0 rg BT 524.35 494.25 Td (development ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 482.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.92 482.25 Td (Progressive ) Tj ET Q q 0 0 0 rg BT 100.84 482.25 Td (Supranuclear ) Tj ET Q q 0 0 0 rg BT 156.85 482.25 Td (Palsy) Tj ET Q q 0 0 0 rg BT 177.87 482.25 Td (. ) Tj ET Q q 0 0 0 rg BT 183.63 482.25 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 215.77 482.25 Td (paid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 236.25 482.25 Td ($300 ) Tj ET Q q 0 0 0 rg BT 259.51 482.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.40 482.25 Td ( ) Tj ET Q q 0 0 0 rg BT 291.66 482.25 Td (to ) Tj ET Q q 0 0 0 rg BT 302.69 482.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 327.07 482.25 Td (which ) Tj ET Q q 0 0 0 rg BT 354.77 482.25 Td (was ) Tj ET Q q 0 0 0 rg BT 373.58 482.25 Td (included ) Tj ET Q q 0 0 0 rg BT 411.27 482.25 Td (in ) Tj ET Q q 0 0 0 rg BT 422.31 482.25 Td (other ) Tj ET Q q 0 0 0 rg BT 446.11 482.25 Td (income. ) Tj ET Q q 0 0 0 rg BT 481.31 482.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 505.69 482.25 Td (is ) Tj ET Q q 0 0 0 rg BT 515.62 482.25 Td (also ) Tj ET Q q 0 0 0 rg BT 534.98 482.25 Td (entitled ) Tj ET Q q 0 0 0 rg BT 568.23 482.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 470.25 Td (contingent ) Tj ET Q q 0 0 0 rg BT 81.29 470.25 Td (development, ) Tj ET Q q 0 0 0 rg BT 138.52 470.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 182.70 470.25 Td (and ) Tj ET Q q 0 0 0 rg BT 200.21 470.25 Td (sales-based ) Tj ET Q q 0 0 0 rg BT 248.83 470.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 290.79 470.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 332.20 470.25 Td (of ) Tj ET Q q 0 0 0 rg BT 343.61 470.25 Td (up ) Tj ET Q q 0 0 0 rg BT 356.69 470.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.55 470.25 Td ($410 ) Tj ET Q q 0 0 0 rg BT 390.63 470.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.52 470.25 Td ( ) Tj ET Q q 0 0 0 rg BT 422.60 470.25 Td (if ) Tj ET Q q 0 0 0 rg BT 431.79 470.25 Td (achieved ) Tj ET Q q 0 0 0 rg BT 470.40 470.25 Td (and ) Tj ET Q q 0 0 0 rg BT 487.92 470.25 Td (future ) Tj ET Q q 0 0 0 rg BT 514.88 470.25 Td (royalties. ) Tj ET Q q 0 0 0 rg BT 554.89 470.25 Td (BMS ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 458.25 Td (originally ) Tj ET Q q 0 0 0 rg BT 78.20 458.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 115.95 458.25 Td (the ) Tj ET Q q 0 0 0 rg BT 131.49 458.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 157.59 458.25 Td (to ) Tj ET Q q 0 0 0 rg BT 168.69 458.25 Td (this ) Tj ET Q q 0 0 0 rg BT 186.46 458.25 Td (compound ) Tj ET Q q 0 0 0 rg BT 232.00 458.25 Td (in ) Tj ET Q q 0 0 0 rg BT 243.10 458.25 Td (2014 ) Tj ET Q q 0 0 0 rg BT 266.43 458.25 Td (through ) Tj ET Q q 0 0 0 rg BT 300.86 458.25 Td (its ) Tj ET Q q 0 0 0 rg BT 313.63 458.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 360.83 458.25 Td (of ) Tj ET Q q 0 0 0 rg BT 372.49 458.25 Td (iPierian. ) Tj ET Q q 0 0 0 rg BT 409.41 458.25 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 441.62 458.25 Td (assumed ) Tj ET Q q 0 0 0 rg BT 479.38 458.25 Td (all ) Tj ET Q q 0 0 0 rg BT 492.70 458.25 Td (of ) Tj ET Q q 0 0 0 rg BT 504.35 458.25 Td (BMS’) Tj ET Q q 0 0 0 rg BT 528.26 458.25 Td (s ) Tj ET Q q 0 0 0 rg BT 535.47 458.25 Td (remaining ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 446.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 82.94 446.25 Td (to ) Tj ET Q q 0 0 0 rg BT 93.22 446.25 Td (the ) Tj ET Q q 0 0 0 rg BT 107.94 446.25 Td (former ) Tj ET Q q 0 0 0 rg BT 137.65 446.25 Td (stockholders ) Tj ET Q q 0 0 0 rg BT 190.69 446.25 Td (of ) Tj ET Q q 0 0 0 rg BT 201.52 446.25 Td (iPierian. ) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 426.9169921875 m 60.9853515625 426.9169921875 l s q 0 0 0 rg BT 36.00 428.25 Td (Roche) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.25 Td (In ) Tj ET Q q 0 0 0 rg BT 48.50 413.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 75.18 413.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 100.47 413.25 Td (out-licensed ) Tj ET Q q 0 0 0 rg BT 153.52 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 165.47 413.25 Td (Roche ) Tj ET Q q 0 0 0 rg BT 195.19 413.25 Td (exclusive ) Tj ET Q q 0 0 0 rg BT 237.13 413.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 264.08 413.25 Td (to ) Tj ET Q q 0 0 0 rg BT 276.03 413.25 Td (develop ) Tj ET Q q 0 0 0 rg BT 311.86 413.25 Td (and ) Tj ET Q q 0 0 0 rg BT 330.47 413.25 Td (commercialize ) Tj ET Q q 0 0 0 rg BT 393.50 413.25 Td (BMS-986089, ) Tj ET Q q 0 0 0 rg BT 454.62 413.25 Td (an ) Tj ET Q q 0 0 0 rg BT 468.24 413.25 Td (anti-myostatin ) Tj ET Q q 0 0 0 rg BT 530.18 413.25 Td (adnectin ) Tj ET Q q 0 0 0 rg BT 568.22 413.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.25 Td (development ) Tj ET Q q 0 0 0 rg BT 90.55 401.25 Td (for ) Tj ET Q q 0 0 0 rg BT 105.12 401.25 Td (Duchenne ) Tj ET Q q 0 0 0 rg BT 148.56 401.25 Td (Muscular ) Tj ET Q q 0 0 0 rg BT 189.23 401.25 Td (Dystrophy) Tj ET Q q 0 0 0 rg BT 230.81 401.25 Td (. ) Tj ET Q q 0 0 0 rg BT 236.21 401.25 Td (Roche ) Tj ET Q q 0 0 0 rg BT 264.66 401.25 Td (paid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 284.78 401.25 Td ($170 ) Tj ET Q q 0 0 0 rg BT 307.69 401.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.58 401.25 Td ( ) Tj ET Q q 0 0 0 rg BT 339.48 401.25 Td (to ) Tj ET Q q 0 0 0 rg BT 350.17 401.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 374.19 401.25 Td (which ) Tj ET Q q 0 0 0 rg BT 401.54 401.25 Td (was ) Tj ET Q q 0 0 0 rg BT 419.99 401.25 Td (included ) Tj ET Q q 0 0 0 rg BT 457.33 401.25 Td (in ) Tj ET Q q 0 0 0 rg BT 468.01 401.25 Td (other ) Tj ET Q q 0 0 0 rg BT 491.46 401.25 Td (income. ) Tj ET Q q 0 0 0 rg BT 526.30 401.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 550.33 401.25 Td (is ) Tj ET Q q 0 0 0 rg BT 559.90 401.25 Td (also ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (entitled ) Tj ET Q q 0 0 0 rg BT 68.49 389.25 Td (to ) Tj ET Q q 0 0 0 rg BT 78.77 389.25 Td (contingent ) Tj ET Q q 0 0 0 rg BT 123.48 389.25 Td (development ) Tj ET Q q 0 0 0 rg BT 177.63 389.25 Td (and ) Tj ET Q q 0 0 0 rg BT 194.57 389.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 238.16 389.25 Td (milestone ) Tj ET Q q 0 0 0 rg BT 279.54 389.25 Td (payments ) Tj ET Q q 0 0 0 rg BT 320.37 389.25 Td (of ) Tj ET Q q 0 0 0 rg BT 331.20 389.25 Td (up ) Tj ET Q q 0 0 0 rg BT 343.70 389.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.98 389.25 Td ($205 ) Tj ET Q q 0 0 0 rg BT 376.48 389.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.37 389.25 Td ( ) Tj ET Q q 0 0 0 rg BT 407.87 389.25 Td (if ) Tj ET Q q 0 0 0 rg BT 416.48 389.25 Td (achieved ) Tj ET Q q 0 0 0 rg BT 454.51 389.25 Td (and ) Tj ET Q q 0 0 0 rg BT 471.45 389.25 Td (future ) Tj ET Q q 0 0 0 rg BT 497.83 389.25 Td (royalties.) Tj ET Q endstream endobj 159 0 obj <> endobj 160 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (79) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 749.25 Td (5) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 749.25 Td (. OTHER INCOME \(NET\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 732.25 Td (Other income \(net\) includes:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 695.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 695.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 695.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 695.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 695.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 695.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 695.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 669.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 669.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 669.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 669.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 669.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 669.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 669.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 643.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 643.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 643.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 643.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 643.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 643.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 643.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 617.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 617.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 617.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 617.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 617.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 617.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 617.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 591.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 591.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 591.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 591.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 591.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 591.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 591.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 565.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 565.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 565.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 565.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 565.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 565.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 565.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 539.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 539.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 539.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 539.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 539.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 539.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 539.75 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 513.75 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 513.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 513.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 513.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 513.75 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 513.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 513.75 70.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 708.75 m 429.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 429.5 708.75 m 433.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 708.75 m 502.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 502.5 708.75 m 506.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 708.75 m 576.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 708.75 m 429.5 708.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 695.75 m 429.5 695.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 695.75 m 576.5 695.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 695.75 m 502.5 695.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 695.75 m 576.5 695.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 513.75 m 502.5 513.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 513.75 m 576.5 513.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 513.75 m 429.5 513.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 501.75 m 429.5 501.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 499.75 m 429.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 501.75 m 502.5 501.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 499.75 m 502.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 501.75 m 576.5 501.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 499.75 m 576.5 499.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 713.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 423.70 712.98 Td (Y) Tj ET Q q 0 0 0 rg BT 429.03 712.98 Td (ear) Tj ET Q q 0 0 0 rg BT 439.62 712.98 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 500.35 712.98 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 700.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 386.50 699.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 459.50 699.98 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.00 699.98 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 686.32 Td (Interest expense) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 686.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 686.32 Td (196) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 686.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 686.32 Td (167) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 686.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 686.32 Td (184) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 673.32 Td (Investment income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.30 673.37 Td (\(154) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 673.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 673.37 Td (\(105) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 673.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 673.32 Td (\(101) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 673.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 660.32 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 660.32 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 660.32 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 660.32 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 660.32 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 647.32 Td (Litigation and other settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.30 647.37 Td (\(487) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 647.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 647.32 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 647.32 Td (159) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 634.32 Td (Equity in net income of af) Tj ET Q q 0 0 0 rg BT 143.60 634.32 Td (filiates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 634.37 Td (\(75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 634.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.30 634.37 Td (\(77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 634.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 634.32 Td (\(83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 634.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 621.32 Td (Divestiture gains) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.30 621.37 Td (\(164) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 621.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 621.37 Td (\(576) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 621.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 621.32 Td (\(196) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 621.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 608.32 Td (Royalties and licensing income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 608.37 Td (\(1,351) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 608.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 608.37 Td (\(719) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 608.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 608.32 Td (\(383) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 608.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 595.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.93 595.32 Td (ransition and other service fees) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 595.37 Td (\(37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 595.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 595.37 Td (\(238) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 595.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 595.32 Td (\(122) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 595.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 582.32 Td (Pension char) Tj ET Q q 0 0 0 rg BT 90.29 582.32 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 582.32 Td (162) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 582.32 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 582.32 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 569.32 Td (Intangible asset impairment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 569.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 569.32 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 569.32 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 556.32 Td (Equity investment impairment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 556.32 Td (5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 556.32 Td (45) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 556.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 543.32 Td (W) Tj ET Q q 0 0 0 rg BT 48.24 543.32 Td (ritten option adjustment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 543.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 543.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 543.32 Td (\(123) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 543.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 530.32 Td (Loss on debt redemption) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 530.32 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 530.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 530.32 Td (180) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 517.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 517.37 Td (\(16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 517.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.30 517.37 Td (\(44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 517.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 517.32 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 504.32 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 504.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 504.37 Td (\(1,519) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 504.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 504.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.80 504.37 Td (\(1,285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 504.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 504.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 504.32 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 504.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 477.25 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 477.25 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 104.44 477.25 Td (and ) Tj ET Q q 0 0 0 rg BT 120.87 477.25 Td (other ) Tj ET Q q 0 0 0 rg BT 143.42 477.25 Td (settlements ) Tj ET Q q 0 0 0 rg BT 190.41 477.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 225.73 477.25 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 254.55 477.25 Td (share ) Tj ET Q q 0 0 0 rg BT 277.64 477.25 Td (of ) Tj ET Q q 0 0 0 rg BT 287.97 477.25 Td (a ) Tj ET Q q 0 0 0 rg BT 294.41 477.25 Td (patent-infringement ) Tj ET Q q 0 0 0 rg BT 375.82 477.25 Td (settlement ) Tj ET Q q 0 0 0 rg BT 418.92 477.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.25 477.25 Td ($481 ) Tj ET Q q 0 0 0 rg BT 451.25 477.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.14 477.25 Td ( ) Tj ET Q q 0 0 0 rg BT 482.14 477.25 Td (related ) Tj ET Q q 0 0 0 rg BT 511.34 477.25 Td (to ) Tj ET Q q 0 0 0 rg BT 521.11 477.25 Td (Merck's ) Tj ET Q q 0 0 0 rg BT 554.90 477.25 Td (PD-1 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 465.25 Td (antibody ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 100.50 465.25 Td (Keytruda) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 137.71 465.25 Td (* ) Tj ET Q q 0 0 0 rg BT 145.21 465.25 Td (in ) Tj ET Q q 0 0 0 rg BT 155.49 465.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 177.99 465.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 194.93 465.25 Td ($90 ) Tj ET Q q 0 0 0 rg BT 212.43 465.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 241.32 465.25 Td ( ) Tj ET Q q 0 0 0 rg BT 243.82 465.25 Td (in ) Tj ET Q q 0 0 0 rg BT 254.10 465.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 276.60 465.25 Td (for ) Tj ET Q q 0 0 0 rg BT 290.76 465.25 Td (a ) Tj ET Q q 0 0 0 rg BT 297.70 465.25 Td (contractual ) Tj ET Q q 0 0 0 rg BT 344.62 465.25 Td (dispute ) Tj ET Q q 0 0 0 rg BT 376.00 465.25 Td (related ) Tj ET Q q 0 0 0 rg BT 405.71 465.25 Td (to ) Tj ET Q q 0 0 0 rg BT 415.98 465.25 Td (a ) Tj ET Q q 0 0 0 rg BT 422.92 465.25 Td (license.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 453.25 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 453.25 Td (Royalties ) Tj ET Q q 0 0 0 rg BT 103.27 453.25 Td (and ) Tj ET Q q 0 0 0 rg BT 120.21 453.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 158.82 453.25 Td (income ) Tj ET Q q 0 0 0 rg BT 190.75 453.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 226.57 453.25 Td (upfront ) Tj ET Q q 0 0 0 rg BT 258.51 453.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 297.12 453.25 Td (fees ) Tj ET Q q 0 0 0 rg BT 315.71 453.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 326.54 453.25 Td ($470 ) Tj ET Q q 0 0 0 rg BT 349.04 453.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 377.94 453.25 Td ( ) Tj ET Q q 0 0 0 rg BT 380.44 453.25 Td (from ) Tj ET Q q 0 0 0 rg BT 402.38 453.25 Td (Biogen ) Tj ET Q q 0 0 0 rg BT 433.76 453.25 Td (and ) Tj ET Q q 0 0 0 rg BT 450.70 453.25 Td (Roche ) Tj ET Q q 0 0 0 rg BT 478.75 453.25 Td (in ) Tj ET Q q 0 0 0 rg BT 489.03 453.25 Td (2017.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 441.25 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 441.25 Td (T) Tj ET Q q 0 0 0 rg BT 68.76 441.25 Td (ransition ) Tj ET Q q 0 0 0 rg BT 107.40 441.25 Td (and ) Tj ET Q q 0 0 0 rg BT 125.49 441.25 Td (other ) Tj ET Q q 0 0 0 rg BT 149.69 441.25 Td (service ) Tj ET Q q 0 0 0 rg BT 181.65 441.25 Td (fees ) Tj ET Q q 0 0 0 rg BT 201.40 441.25 Td (were ) Tj ET Q q 0 0 0 rg BT 224.48 441.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 265.34 441.25 Td (related ) Tj ET Q q 0 0 0 rg BT 296.19 441.25 Td (to ) Tj ET Q q 0 0 0 rg BT 307.62 441.25 Td (the ) Tj ET Q q 0 0 0 rg BT 323.49 441.25 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 369.35 441.25 Td (of ) Tj ET Q q 0 0 0 rg BT 381.33 441.25 Td (the ) Tj ET Q q 0 0 0 rg BT 397.20 441.25 Td (diabetes ) Tj ET Q q 0 0 0 rg BT 433.61 441.25 Td (and ) Tj ET Q q 0 0 0 rg BT 451.70 441.25 Td (investigational ) Tj ET Q q 0 0 0 rg BT 514.23 441.25 Td (HIV) Tj ET Q q 0 0 0 rg BT 531.82 441.25 Td ( ) Tj ET Q q 0 0 0 rg BT 535.47 441.25 Td (medicines ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 429.25 Td (businesses.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 417.25 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 417.25 Td (W) Tj ET Q q 0 0 0 rg BT 72.04 417.25 Td (ritten ) Tj ET Q q 0 0 0 rg BT 95.64 417.25 Td (option ) Tj ET Q q 0 0 0 rg BT 123.70 417.25 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 170.08 417.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 205.91 417.25 Td (the ) Tj ET Q q 0 0 0 rg BT 220.62 417.25 Td (change ) Tj ET Q q 0 0 0 rg BT 251.44 417.25 Td (in ) Tj ET Q q 0 0 0 rg BT 261.72 417.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 278.09 417.25 Td (value ) Tj ET Q q 0 0 0 rg BT 302.25 417.25 Td (of ) Tj ET Q q 0 0 0 rg BT 313.08 417.25 Td (the ) Tj ET Q q 0 0 0 rg BT 327.79 417.25 Td (written ) Tj ET Q q 0 0 0 rg BT 358.62 417.25 Td (option ) Tj ET Q q 0 0 0 rg BT 386.68 417.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 420.29 417.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 461.11 417.25 Td (to ) Tj ET Q q 0 0 0 rg BT 471.38 417.25 Td (the ) Tj ET Q q 0 0 0 rg BT 486.10 417.25 Td (Reckitt ) Tj ET Q q 0 0 0 rg BT 517.48 417.25 Td (alliance.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 405.25 Td (• ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 405.25 Td (Other ) Tj ET Q q 0 0 0 rg BT 89.23 405.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 126.01 405.25 Td (an ) Tj ET Q q 0 0 0 rg BT 138.91 405.25 Td (unrealized ) Tj ET Q q 0 0 0 rg BT 184.01 405.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 216.34 405.25 Td (exchange ) Tj ET Q q 0 0 0 rg BT 257.55 405.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 276.57 405.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.36 405.25 Td ($52 ) Tj ET Q q 0 0 0 rg BT 306.82 405.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.71 405.25 Td ( ) Tj ET Q q 0 0 0 rg BT 339.17 405.25 Td (in ) Tj ET Q q 0 0 0 rg BT 350.41 405.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 373.87 405.25 Td (resulting ) Tj ET Q q 0 0 0 rg BT 412.32 405.25 Td (from ) Tj ET Q q 0 0 0 rg BT 435.22 405.25 Td (the ) Tj ET Q q 0 0 0 rg BT 450.89 405.25 Td (remeasurement ) Tj ET Q q 0 0 0 rg BT 515.43 405.25 Td (of ) Tj ET Q q 0 0 0 rg BT 527.22 405.25 Td (the ) Tj ET Q q 0 0 0 rg BT 542.89 405.25 Td (Bolivar) Tj ET Q q 0 0 0 rg BT 572.69 405.25 Td (-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 393.25 Td (denominated ) Tj ET Q q 0 0 0 rg BT 117.15 393.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 137.42 393.25 Td (and ) Tj ET Q q 0 0 0 rg BT 154.36 393.25 Td (other ) Tj ET Q q 0 0 0 rg BT 177.40 393.25 Td (monetary ) Tj ET Q q 0 0 0 rg BT 217.67 393.25 Td (balances ) Tj ET Q q 0 0 0 rg BT 254.59 393.25 Td (of ) Tj ET Q q 0 0 0 rg BT 265.42 393.25 Td (BMS’) Tj ET Q q 0 0 0 rg BT 289.32 393.25 Td (s ) Tj ET Q q 0 0 0 rg BT 295.71 393.25 Td (wholly-owned ) Tj ET Q q 0 0 0 rg BT 355.98 393.25 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 399.59 393.25 Td (in ) Tj ET Q q 0 0 0 rg BT 409.69 393.25 Td (V) Tj ET Q q 0 0 0 rg BT 415.80 393.25 Td (enezuela ) Tj ET Q q 0 0 0 rg BT 453.27 393.25 Td (as ) Tj ET Q q 0 0 0 rg BT 464.10 393.25 Td (of ) Tj ET Q q 0 0 0 rg BT 474.93 393.25 Td (December ) Tj ET Q q 0 0 0 rg BT 518.52 393.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 533.52 393.25 Td (2015.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 369.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 369.25 Td (6) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 369.25 Td (. RESTRUCTURING) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 345.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.53 345.25 Td (October ) Tj ET Q q 0 0 0 rg BT 80.93 345.25 Td (2016, ) Tj ET Q q 0 0 0 rg BT 105.63 345.25 Td (the ) Tj ET Q q 0 0 0 rg BT 120.05 345.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 161.13 345.25 Td (announced ) Tj ET Q q 0 0 0 rg BT 206.65 345.25 Td (a ) Tj ET Q q 0 0 0 rg BT 213.29 345.25 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 266.58 345.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 285.99 345.25 Td (to ) Tj ET Q q 0 0 0 rg BT 295.97 345.25 Td (evolve ) Tj ET Q q 0 0 0 rg BT 324.82 345.25 Td (and ) Tj ET Q q 0 0 0 rg BT 341.46 345.25 Td (streamline ) Tj ET Q q 0 0 0 rg BT 385.31 345.25 Td (its ) Tj ET Q q 0 0 0 rg BT 396.96 345.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 436.92 345.25 Td (model ) Tj ET Q q 0 0 0 rg BT 464.11 345.25 Td (and ) Tj ET Q q 0 0 0 rg BT 480.75 345.25 Td (expects ) Tj ET Q q 0 0 0 rg BT 512.94 345.25 Td (to ) Tj ET Q q 0 0 0 rg BT 522.91 345.25 Td (incur ) Tj ET Q q 0 0 0 rg BT 545.66 345.25 Td (char) Tj ET Q q 0 0 0 rg BT 562.68 345.25 Td (ges ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 333.25 Td (in ) Tj ET Q q 0 0 0 rg BT 45.75 333.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 91.59 333.25 Td (with ) Tj ET Q q 0 0 0 rg BT 111.34 333.25 Td (employee ) Tj ET Q q 0 0 0 rg BT 152.18 333.25 Td (workforce ) Tj ET Q q 0 0 0 rg BT 195.24 333.25 Td (reductions ) Tj ET Q q 0 0 0 rg BT 238.87 333.25 Td (and ) Tj ET Q q 0 0 0 rg BT 255.27 333.25 Td (early ) Tj ET Q q 0 0 0 rg BT 277.23 333.25 Td (site ) Tj ET Q q 0 0 0 rg BT 293.09 333.25 Td (exits. ) Tj ET Q q 0 0 0 rg BT 316.30 333.25 Td (The ) Tj ET Q q 0 0 0 rg BT 333.82 333.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 369.67 333.25 Td (of ) Tj ET Q q 0 0 0 rg BT 379.97 333.25 Td (char) Tj ET Q q 0 0 0 rg BT 397.00 333.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 412.30 333.25 Td (are ) Tj ET Q q 0 0 0 rg BT 426.48 333.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 463.98 333.25 Td (to ) Tj ET Q q 0 0 0 rg BT 473.73 333.25 Td (be ) Tj ET Q q 0 0 0 rg BT 485.13 333.25 Td (incurred ) Tj ET Q q 0 0 0 rg BT 520.42 333.25 Td (through ) Tj ET Q q 0 0 0 rg BT 553.50 333.25 Td (2020, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 321.25 Td (range ) Tj ET Q q 0 0 0 rg BT 61.47 321.25 Td (between ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 98.05 321.25 Td ($1.5 ) Tj ET Q q 0 0 0 rg BT 118.81 321.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 144.92 321.25 Td ( ) Tj ET Q q 0 0 0 rg BT 148.18 321.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.22 321.25 Td ($2.0 ) Tj ET Q q 0 0 0 rg BT 179.98 321.25 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.10 321.25 Td (, ) Tj ET Q q 0 0 0 rg BT 211.86 321.25 Td (and ) Tj ET Q q 0 0 0 rg BT 229.56 321.25 Td (consist ) Tj ET Q q 0 0 0 rg BT 260.60 321.25 Td (of ) Tj ET Q q 0 0 0 rg BT 272.19 321.25 Td (employee ) Tj ET Q q 0 0 0 rg BT 314.33 321.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 363.69 321.25 Td (benefit ) Tj ET Q q 0 0 0 rg BT 394.71 321.25 Td (costs, ) Tj ET Q q 0 0 0 rg BT 420.47 321.25 Td (contract ) Tj ET Q q 0 0 0 rg BT 455.94 321.25 Td (termination ) Tj ET Q q 0 0 0 rg BT 505.30 321.25 Td (costs, ) Tj ET Q q 0 0 0 rg BT 531.06 321.25 Td (accelerated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 309.25 Td (depreciation, ) Tj ET Q q 0 0 0 rg BT 89.78 309.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 137.74 309.25 Td (char) Tj ET Q q 0 0 0 rg BT 154.77 309.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 169.96 309.25 Td (and ) Tj ET Q q 0 0 0 rg BT 186.26 309.25 Td (other ) Tj ET Q q 0 0 0 rg BT 208.67 309.25 Td (site ) Tj ET Q q 0 0 0 rg BT 224.42 309.25 Td (exit ) Tj ET Q q 0 0 0 rg BT 241.27 309.25 Td (costs. ) Tj ET Q q 0 0 0 rg BT 265.64 309.25 Td (Cash ) Tj ET Q q 0 0 0 rg BT 287.50 309.25 Td (outlays ) Tj ET Q q 0 0 0 rg BT 318.25 309.25 Td (in ) Tj ET Q q 0 0 0 rg BT 327.89 309.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 373.62 309.25 Td (with ) Tj ET Q q 0 0 0 rg BT 393.26 309.25 Td (these ) Tj ET Q q 0 0 0 rg BT 415.67 309.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 445.86 309.25 Td (are ) Tj ET Q q 0 0 0 rg BT 459.92 309.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 497.32 309.25 Td (to ) Tj ET Q q 0 0 0 rg BT 506.96 309.25 Td (be ) Tj ET Q q 0 0 0 rg BT 518.26 309.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 297.25 Td (40%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.33 297.25 Td ( ) Tj ET Q q 0 0 0 rg BT 56.51 297.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.47 297.25 Td (50%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 84.80 297.25 Td ( ) Tj ET Q q 0 0 0 rg BT 86.98 297.25 Td (of ) Tj ET Q q 0 0 0 rg BT 97.49 297.25 Td (the ) Tj ET Q q 0 0 0 rg BT 111.89 297.25 Td (total ) Tj ET Q q 0 0 0 rg BT 131.84 297.25 Td (char) Tj ET Q q 0 0 0 rg BT 148.87 297.25 Td (ges. ) Tj ET Q q 0 0 0 rg BT 166.88 297.25 Td (Char) Tj ET Q q 0 0 0 rg BT 186.13 297.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 201.64 297.25 Td (of ) Tj ET Q q 0 0 0 rg BT 212.15 297.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.09 297.25 Td ($800 ) Tj ET Q q 0 0 0 rg BT 294.27 297.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.17 297.25 Td ( ) Tj ET Q q 0 0 0 rg BT 325.35 297.25 Td (have ) Tj ET Q q 0 0 0 rg BT 346.40 297.25 Td (been ) Tj ET Q q 0 0 0 rg BT 367.46 297.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 413.50 297.25 Td (for ) Tj ET Q q 0 0 0 rg BT 427.34 297.25 Td (these ) Tj ET Q q 0 0 0 rg BT 450.07 297.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 480.58 297.25 Td (since ) Tj ET Q q 0 0 0 rg BT 503.30 297.25 Td (the ) Tj ET Q q 0 0 0 rg BT 517.70 297.25 Td (announcement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 285.25 Td (including ) Tj ET Q q 0 0 0 rg BT 76.13 285.25 Td (an ) Tj ET Q q 0 0 0 rg BT 87.93 285.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 136.39 285.25 Td (char) Tj ET Q q 0 0 0 rg BT 153.42 285.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 165.22 285.25 Td (for ) Tj ET Q q 0 0 0 rg BT 179.24 285.25 Td (a ) Tj ET Q q 0 0 0 rg BT 186.04 285.25 Td (small ) Tj ET Q q 0 0 0 rg BT 210.06 285.25 Td (molecule ) Tj ET Q q 0 0 0 rg BT 249.08 285.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 309.75 285.25 Td (operation ) Tj ET Q q 0 0 0 rg BT 349.87 285.25 Td (in ) Tj ET Q q 0 0 0 rg BT 360.01 285.25 Td (Swords, ) Tj ET Q q 0 0 0 rg BT 394.88 285.25 Td (Ireland. ) Tj ET Q q 0 0 0 rg BT 428.05 285.25 Td (Restructuring ) Tj ET Q q 0 0 0 rg BT 484.85 285.25 Td (char) Tj ET Q q 0 0 0 rg BT 501.87 285.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 517.56 285.25 Td (are ) Tj ET Q q 0 0 0 rg BT 532.13 285.25 Td (recognized ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 273.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 58.46 273.25 Td (meeting ) Tj ET Q q 0 0 0 rg BT 93.13 273.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 122.79 273.25 Td (criteria, ) Tj ET Q q 0 0 0 rg BT 156.06 273.25 Td (including ) Tj ET Q q 0 0 0 rg BT 196.30 273.25 Td (finalization ) Tj ET Q q 0 0 0 rg BT 244.29 273.25 Td (of ) Tj ET Q q 0 0 0 rg BT 255.08 273.25 Td (committed ) Tj ET Q q 0 0 0 rg BT 300.31 273.25 Td (plans, ) Tj ET Q q 0 0 0 rg BT 326.38 273.25 Td (reliable ) Tj ET Q q 0 0 0 rg BT 358.82 273.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 398.49 273.25 Td (and ) Tj ET Q q 0 0 0 rg BT 415.39 273.25 Td (discussions ) Tj ET Q q 0 0 0 rg BT 463.41 273.25 Td (with ) Tj ET Q q 0 0 0 rg BT 483.65 273.25 Td (local ) Tj ET Q q 0 0 0 rg BT 505.55 273.25 Td (works ) Tj ET Q q 0 0 0 rg BT 532.45 273.25 Td (councils ) Tj ET Q q 0 0 0 rg BT 568.23 273.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 261.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 65.70 261.25 Td (markets.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 237.25 Td (Other ) Tj ET Q q 0 0 0 rg BT 62.12 237.25 Td (restructuring ) Tj ET Q q 0 0 0 rg BT 116.57 237.25 Td (char) Tj ET Q q 0 0 0 rg BT 133.60 237.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 150.29 237.25 Td (in ) Tj ET Q q 0 0 0 rg BT 161.42 237.25 Td (addition ) Tj ET Q q 0 0 0 rg BT 197.55 237.25 Td (to ) Tj ET Q q 0 0 0 rg BT 208.68 237.25 Td (the ) Tj ET Q q 0 0 0 rg BT 224.26 237.25 Td (above ) Tj ET Q q 0 0 0 rg BT 251.49 237.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 283.17 237.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 330.39 237.25 Td (prior ) Tj ET Q q 0 0 0 rg BT 353.18 237.25 Td (were ) Tj ET Q q 0 0 0 rg BT 375.97 237.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 416.54 237.25 Td (related ) Tj ET Q q 0 0 0 rg BT 447.09 237.25 Td (to ) Tj ET Q q 0 0 0 rg BT 458.23 237.25 Td (specialty ) Tj ET Q q 0 0 0 rg BT 497.13 237.25 Td (care ) Tj ET Q q 0 0 0 rg BT 517.13 237.25 Td (transformation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 225.25 Td (initiatives ) Tj ET Q q 0 0 0 rg BT 79.45 225.25 Td (designed ) Tj ET Q q 0 0 0 rg BT 119.02 225.25 Td (to ) Tj ET Q q 0 0 0 rg BT 130.81 225.25 Td (create ) Tj ET Q q 0 0 0 rg BT 158.69 225.25 Td (a ) Tj ET Q q 0 0 0 rg BT 167.15 225.25 Td (more ) Tj ET Q q 0 0 0 rg BT 191.71 225.25 Td (simplified ) Tj ET Q q 0 0 0 rg BT 236.28 225.25 Td (or) Tj ET Q q 0 0 0 rg BT 244.43 225.25 Td (ganization ) Tj ET Q q 0 0 0 rg BT 290.09 225.25 Td (across ) Tj ET Q q 0 0 0 rg BT 319.10 225.25 Td (all ) Tj ET Q q 0 0 0 rg BT 333.11 225.25 Td (functions ) Tj ET Q q 0 0 0 rg BT 374.34 225.25 Td (and ) Tj ET Q q 0 0 0 rg BT 392.80 225.25 Td (geographic ) Tj ET Q q 0 0 0 rg BT 441.24 225.25 Td (markets. ) Tj ET Q q 0 0 0 rg BT 479.41 225.25 Td (In ) Tj ET Q q 0 0 0 rg BT 491.75 225.25 Td (addition, ) Tj ET Q q 0 0 0 rg BT 531.04 225.25 Td (accelerated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 213.25 Td (depreciation ) Tj ET Q q 0 0 0 rg BT 88.86 213.25 Td (and ) Tj ET Q q 0 0 0 rg BT 106.74 213.25 Td (other ) Tj ET Q q 0 0 0 rg BT 130.73 213.25 Td (char) Tj ET Q q 0 0 0 rg BT 147.75 213.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 164.53 213.25 Td (were ) Tj ET Q q 0 0 0 rg BT 187.40 213.25 Td (incurred ) Tj ET Q q 0 0 0 rg BT 224.15 213.25 Td (in ) Tj ET Q q 0 0 0 rg BT 235.37 213.25 Td (connection ) Tj ET Q q 0 0 0 rg BT 282.69 213.25 Td (with ) Tj ET Q q 0 0 0 rg BT 303.91 213.25 Td (the ) Tj ET Q q 0 0 0 rg BT 319.56 213.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 358.54 213.25 Td (early ) Tj ET Q q 0 0 0 rg BT 381.96 213.25 Td (exits ) Tj ET Q q 0 0 0 rg BT 404.29 213.25 Td (of ) Tj ET Q q 0 0 0 rg BT 416.06 213.25 Td (a ) Tj ET Q q 0 0 0 rg BT 423.94 213.25 Td (small ) Tj ET Q q 0 0 0 rg BT 449.05 213.25 Td (molecule ) Tj ET Q q 0 0 0 rg BT 489.14 213.25 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 550.89 213.25 Td (site ) Tj ET Q q 0 0 0 rg BT 568.22 213.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 201.25 Td (Cruiserath, ) Tj ET Q q 0 0 0 rg BT 84.18 201.25 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 116.52 201.25 Td (and ) Tj ET Q q 0 0 0 rg BT 134.99 201.25 Td (a ) Tj ET Q q 0 0 0 rg BT 143.45 201.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 169.15 201.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 201.49 201.25 Td (in ) Tj ET Q q 0 0 0 rg BT 213.01 201.25 Td (W) Tj ET Q q 0 0 0 rg BT 221.64 201.25 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 267.60 201.25 Td (Connecticut. ) Tj ET Q q 0 0 0 rg BT 322.45 201.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 348.68 201.25 Td (to ) Tj ET Q q 0 0 0 rg BT 360.49 201.25 Td ("—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.03 201.25 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.03 201.25 Td (. ) Tj ET Q q 0 0 0 rg BT 408.67 201.25 Td (Acquisitions, ) Tj ET Q q 0 0 0 rg BT 465.75 201.25 Td (Divestitures ) Tj ET Q q 0 0 0 rg BT 518.10 201.25 Td (and ) Tj ET Q q 0 0 0 rg BT 536.57 201.25 Td (Licensing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 189.25 Td (Arrangements" ) Tj ET Q q 0 0 0 rg BT 99.23 189.25 Td (for ) Tj ET Q q 0 0 0 rg BT 113.39 189.25 Td (further ) Tj ET Q q 0 0 0 rg BT 143.09 189.25 Td (information. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 165.25 Td (Employee ) Tj ET Q q 0 0 0 rg BT 79.04 165.25 Td (workforce ) Tj ET Q q 0 0 0 rg BT 122.63 165.25 Td (reductions ) Tj ET Q q 0 0 0 rg BT 166.79 165.25 Td (were ) Tj ET Q q 0 0 0 rg BT 188.71 165.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 248.97 165.25 Td (1,900) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 271.47 165.25 Td ( ) Tj ET Q q 0 0 0 rg BT 273.97 165.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 284.25 165.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.25 165.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.25 165.25 Td (1,100) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.75 165.25 Td ( ) Tj ET Q q 0 0 0 rg BT 334.25 165.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.53 165.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.53 165.25 Td ( ) Tj ET Q q 0 0 0 rg BT 367.03 165.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.97 165.25 Td (1,200) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.47 165.25 Td ( ) Tj ET Q q 0 0 0 rg BT 408.97 165.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.25 165.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.25 165.25 Td (.) Tj ET Q endstream endobj 161 0 obj <> endobj 162 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (80) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The following tables summarize the char) Tj ET Q q 0 0 0 rg BT 199.37 749.10 Td (ges and activity related to the restructuring actions:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 708.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 708.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 708.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 708.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 708.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 708.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 708.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 678.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 678.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 678.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 678.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 678.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 678.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 678.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 648.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 648.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 648.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 648.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 648.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 648.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 648.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 618.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 618.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 618.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 618.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 618.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 618.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 618.60 70.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 723.6 m 427.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 723.6 m 431.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 723.6 m 501.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 723.6 m 505.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 723.6 m 575.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 723.6 m 427.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 708.6 m 427.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 723.6 m 431.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 723.6 m 501.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 708.6 m 501.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 723.6 m 505.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 723.6 m 575.5 723.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 708.6 m 575.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 708.6 m 427.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 708.6 m 501.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 708.6 m 575.5 708.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 678.6 m 427.5 678.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 678.6 m 501.5 678.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 678.6 m 575.5 678.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 618.6 m 427.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 604.6 m 427.5 604.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 602.6 m 427.5 602.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 618.6 m 501.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 604.6 m 501.5 604.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 602.6 m 501.5 602.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 618.6 m 575.5 618.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 604.6 m 575.5 604.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 602.6 m 575.5 602.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 727.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 727.83 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 727.83 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 727.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 727.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 712.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.00 712.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.00 712.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.00 712.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 699.17 Td (Employee termination costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 698.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 698.27 Td (267) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 698.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 698.27 Td (97) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 698.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 698.27 Td (1) Tj ET Q q 0 0 0 rg BT 561.65 698.27 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 684.17 Td (Other termination costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 683.27 Td (26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 683.27 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 683.27 Td (8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 669.17 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 668.27 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 668.27 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 668.27 Td (1) Tj ET Q q 0 0 0 rg BT 561.65 668.27 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 654.17 Td (Accelerated depreciation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 653.27 Td (289) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 653.27 Td (72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 653.27 Td (104) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 638.27 Td (Asset impairments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 638.27 Td (241) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 638.27 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 638.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 623.27 Td (Other shutdown costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 623.27 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 623.27 Td (19) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 623.27 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 608.27 Td (T) Tj ET Q q 0 0 0 rg BT 43.41 608.27 Td (otal char) Tj ET Q q 0 0 0 rg BT 77.93 608.27 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 608.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 608.27 Td (826) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 608.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 608.27 Td (213) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 608.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 608.27 Td (233) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 551.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 551.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 551.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 551.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 551.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 551.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 551.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 521.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 521.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 521.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 521.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 521.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 521.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 521.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 491.60 318.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 491.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 491.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 491.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 491.60 70.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 491.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 491.60 70.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 566.6 m 427.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 566.6 m 431.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 566.6 m 501.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 566.6 m 505.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 566.6 m 575.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 566.6 m 427.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 551.6 m 427.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 566.6 m 431.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 566.6 m 501.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 551.6 m 501.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 566.6 m 505.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 566.6 m 575.5 566.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 551.6 m 575.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 551.6 m 427.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 551.6 m 501.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 551.6 m 575.5 551.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 491.6 m 427.5 491.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 491.6 m 501.5 491.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 491.6 m 575.5 491.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 477.6 m 427.5 477.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 475.6 m 427.5 475.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 477.6 m 501.5 477.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 475.6 m 501.5 475.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 477.6 m 575.5 477.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 475.6 m 575.5 475.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 570.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 570.83 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 570.83 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 570.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 570.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 555.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.00 555.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.00 555.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.00 555.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 542.17 Td (Cost of products sold) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 541.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 541.27 Td (149) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 541.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 541.27 Td (21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 541.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 541.27 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 527.17 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.65 526.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 526.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 526.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 512.17 Td (Research and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 511.27 Td (383) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 511.27 Td (83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 511.27 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 497.17 Td (Other income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 496.27 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 496.27 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 496.27 Td (1) Tj ET Q q 0 0 0 rg BT 561.65 496.27 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 482.17 Td (T) Tj ET Q q 0 0 0 rg BT 43.41 482.17 Td (otal char) Tj ET Q q 0 0 0 rg BT 77.93 482.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 481.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 481.27 Td (826) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 481.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 481.27 Td (213) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 481.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 481.27 Td (233) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 430.60 317.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 430.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 430.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 430.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 430.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 430.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 430.60 71.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 402.60 317.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 402.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 402.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 402.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 402.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 402.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 402.60 71.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 374.60 317.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 374.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 374.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 374.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 374.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 374.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 374.60 71.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 346.60 317.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 346.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 346.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 346.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 346.60 70.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 346.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 346.60 71.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 442.6 m 427.5 442.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 427.5 442.6 m 431.5 442.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 442.6 m 501.5 442.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 442.6 m 505.5 442.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 442.6 m 576.5 442.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 430.6 m 427.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 430.6 m 501.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 430.6 m 576.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 430.6 m 501.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 430.6 m 576.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 388.6 m 427.5 388.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 388.6 m 501.5 388.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 388.6 m 576.5 388.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 346.6 m 427.5 346.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 346.6 m 501.5 346.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 346.6 m 576.5 346.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 333.6 m 427.5 333.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 331.6 m 427.5 331.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 333.6 m 501.5 333.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 331.6 m 501.5 331.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 333.6 m 576.5 333.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 331.6 m 576.5 331.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 446.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 422.20 446.68 Td (Y) Tj ET Q q 0 0 0 rg BT 427.53 446.68 Td (ear) Tj ET Q q 0 0 0 rg BT 438.12 446.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.85 446.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 434.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.00 434.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.00 434.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 434.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 421.17 Td (Liability at January 1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 421.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 421.17 Td (1) Tj ET Q q 0 0 0 rg BT 413.65 421.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 421.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 421.17 Td (125) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 421.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 421.17 Td (156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 407.17 Td (Char) Tj ET Q q 0 0 0 rg BT 58.35 407.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 407.17 Td (319) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 407.17 Td (1) Tj ET Q q 0 0 0 rg BT 487.65 407.17 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 407.17 Td (133) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 393.17 Td (Change in estimates) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.30 393.22 Td (\(26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.65 393.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.30 393.22 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 393.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 393.17 Td (\(15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 393.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 379.17 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 379.17 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 379.17 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 379.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 379.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 365.17 Td (Foreign currency translation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 365.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 365.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 365.17 Td (\(15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 365.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 351.17 Td (Spending) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.30 351.22 Td (\(239) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.65 351.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 351.22 Td (\(120) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 351.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 351.17 Td (\(134) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 351.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 337.17 Td (Liability at December 31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 337.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.65 337.17 Td (186) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 337.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 337.17 Td (1) Tj ET Q q 0 0 0 rg BT 487.65 337.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 337.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 337.17 Td (125) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 307.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 307.10 Td (7) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 307.10 Td (. INCOME ) Tj ET Q q 0 0 0 rg BT 113.03 307.10 Td (T) Tj ET Q q 0 0 0 rg BT 118.96 307.10 Td (AXES) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 283.10 Td (The provision/\(benefit\) for income taxes consisted of:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 248.60 316.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 248.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 248.60 70.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 248.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 248.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 248.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 248.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 224.60 316.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 224.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 224.60 70.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 224.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 224.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 224.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 224.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 200.60 316.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 200.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 200.60 70.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 200.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 200.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 200.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 200.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 176.60 316.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 176.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 176.60 70.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 176.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 176.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 176.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 176.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 152.60 316.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 152.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 152.60 70.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 152.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 152.60 71.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 152.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 152.60 71.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 260.6 m 426.5 260.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 426.5 260.6 m 430.5 260.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 260.6 m 501.5 260.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 260.6 m 505.5 260.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 260.6 m 576.5 260.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 248.60000000000002 m 426.5 248.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 248.60000000000002 m 501.5 248.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 248.60000000000002 m 576.5 248.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 212.60000000000002 m 426.5 212.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 212.60000000000002 m 501.5 212.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 212.60000000000002 m 576.5 212.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 200.60000000000002 m 426.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 200.60000000000002 m 501.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 200.60000000000002 m 576.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 164.60000000000002 m 426.5 164.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 164.60000000000002 m 501.5 164.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 164.60000000000002 m 576.5 164.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 152.60000000000002 m 426.5 152.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 152.60000000000002 m 501.5 152.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 152.60000000000002 m 576.5 152.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 141.60000000000002 m 426.5 141.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 139.60000000000002 m 426.5 139.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 152.60000000000002 m 501.5 152.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 141.60000000000002 m 501.5 141.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 139.60000000000002 m 501.5 139.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 141.60000000000002 m 576.5 141.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 139.60000000000002 m 576.5 139.60000000000002 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 264.68 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 264.68 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 264.68 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 264.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 252.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 383.00 252.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 457.50 252.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 252.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 239.22 Td (Current:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 227.22 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.00 227.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 227.22 Td (2,782) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 227.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 227.22 Td (1,144) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 227.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 227.22 Td (337) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 215.22 Td (Non-U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 215.22 Td (364) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 215.22 Td (468) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 215.22 Td (456) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 203.22 Td (T) Tj ET Q q 0 0 0 rg BT 62.76 203.22 Td (otal Current) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 203.22 Td (3,146) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 203.22 Td (1,612) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 203.22 Td (793) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 191.22 Td (Deferred:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 179.22 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 179.22 Td (1,063) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 179.22 Td (\(101) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 179.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 179.22 Td (\(394) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 179.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 167.22 Td (Non-U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.30 167.22 Td (\(53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.65 167.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 167.22 Td (\(103) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 167.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 167.22 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 155.22 Td (T) Tj ET Q q 0 0 0 rg BT 62.41 155.22 Td (otal Deferred) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 155.22 Td (1,010) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 155.22 Td (\(204) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 155.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 155.22 Td (\(347) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 155.22 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 143.22 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 143.22 Td (otal Provision) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.00 143.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 143.22 Td (4,156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 143.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 143.22 Td (1,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 143.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 143.22 Td (446) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 163 0 obj <> endobj 164 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (81) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 747.7669921875 m 108.3828125 747.7669921875 l s q 0 0 0 rg BT 36.00 749.10 Td (Effective T) Tj ET Q q 0 0 0 rg BT 78.12 749.10 Td (ax Rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (The reconciliation of the ef) Tj ET Q q 0 0 0 rg BT 144.66 725.10 Td (fective tax/\(benefit\) rate to the U.S. statutory Federal income tax rate was:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 688.60 282.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 318.50 688.60 39.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 688.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 688.60 39.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 400.50 688.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 688.60 39.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 688.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 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529.5 688.6 m 533.5 688.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 533.5 688.6 m 572.5 688.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 649.6 m 357.5 649.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 649.6 m 443.5 649.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 649.6 m 529.5 649.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 636.6 m 357.5 636.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 636.6 m 443.5 636.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 636.6 m 529.5 636.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 438.6 m 357.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 438.6 m 400.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 438.6 m 443.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 438.6 m 486.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 438.6 m 529.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 533.5 438.6 m 572.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 426.6 m 357.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 424.6 m 357.5 424.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 438.6 m 400.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 426.6 m 400.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 424.6 m 400.5 424.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 426.6 m 443.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 404.5 424.6 m 443.5 424.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 438.6 m 486.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 426.6 m 486.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 424.6 m 486.5 424.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 426.6 m 529.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 424.6 m 529.5 424.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 533.5 426.6 m 572.5 426.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 533.5 424.6 m 572.5 424.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 383.60 705.83 Td (% of Earnings Befor) Tj ET Q q 0 0 0 rg BT 454.41 705.83 Td (e Income ) Tj ET Q q 0 0 0 rg BT 487.15 705.83 Td (T) Tj ET Q q 0 0 0 rg BT 492.05 705.83 Td (axes) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 692.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 351.00 692.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.00 692.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 523.00 692.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 679.17 Td (Earnings/\(Loss\) before income taxes:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 666.17 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.00 666.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 666.17 Td (2,280) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.00 666.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.10 666.17 Td (3,100) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.00 666.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.80 666.22 Td (\(1,329) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 666.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 653.17 Td (Non-U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 653.17 Td (2,851) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.10 653.17 Td (2,815) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.10 653.17 Td (3,406) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 640.17 Td (T) Tj ET Q q 0 0 0 rg BT 62.41 640.17 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.00 640.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 640.17 Td (5,131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.00 640.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.10 640.17 Td (5,915) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.00 640.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 503.10 640.17 Td (2,077) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 627.17 Td (U.S. statutory rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 627.17 Td (1,796) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.80 627.17 Td (35.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 627.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.10 627.17 Td (2,070) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 456.80 627.17 Td (35.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 627.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.65 627.17 Td (727) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 542.80 627.17 Td (35.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 627.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 614.17 Td (Deemed repatriation transition tax) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 613.27 Td (2,61) Tj ET Q q 0 0 0 rg BT 348.60 613.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.80 613.27 Td (50.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 613.27 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 613.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.30 613.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 613.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.30 613.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 599.17 Td (Deferred tax remeasurement) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 338.65 598.27 Td (285) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 598.27 Td (5.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 598.27 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 598.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.30 598.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 598.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.30 598.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 584.17 Td (Foreign tax ef) Tj ET Q q 0 0 0 rg BT 95.00 584.17 Td (fect of certain operations in Ireland, Puerto Rico and) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 574.17 Td (Switzerland) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.30 573.32 Td (\(561) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.65 573.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.45 573.27 Td (\(10.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.30 573.27 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.30 573.32 Td (\(442) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 573.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 573.27 Td (\(7.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 573.27 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.30 573.32 Td (\(535) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 573.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 539.45 573.27 Td (\(25.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.30 573.27 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 559.17 Td (U.S. Federal valuation allowance release) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.65 559.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.30 559.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.30 559.22 Td (\(29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 559.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 559.17 Td (\(0.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 559.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.30 559.22 Td (\(84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 559.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.45 559.17 Td (\(4.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.30 559.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 546.17 Td (U.S. Federal, state and foreign contingent tax matters) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.65 546.17 Td (72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 546.17 Td (1.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 546.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 546.17 Td (87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 546.17 Td (1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 546.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 546.17 Td (56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.80 546.17 Td (2.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 546.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 533.17 Td (U.S. Federal research based credits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.30 533.22 Td (\(144) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.65 533.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.45 533.17 Td (\(2.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.30 533.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.30 533.22 Td (\(144) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 533.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 533.17 Td (\(2.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 533.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.30 533.22 Td (\(132) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 533.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.45 533.17 Td (\(6.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.30 533.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 520.17 Td (Goodwill allocated to divestitures) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 348.65 520.17 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 520.17 Td (0.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 520.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 520.17 Td (34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 520.17 Td (0.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 520.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 520.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.80 520.17 Td (1.2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 520.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 507.17 Td (U.S. Branded Prescription Drug Fee) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.65 507.17 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 507.17 Td (1.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 507.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 507.17 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 507.17 Td (0.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 507.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 507.17 Td (44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.80 507.17 Td (2.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 507.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 494.17 Td (Non-deductible R&D char) Tj ET Q q 0 0 0 rg BT 144.99 494.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 338.65 494.17 Td (266) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 494.17 Td (5.2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 494.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.65 494.17 Td (100) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 494.17 Td (1.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 494.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.65 494.17 Td (369) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 542.80 494.17 Td (17.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 494.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 481.17 Td (Puerto Rico excise tax) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.30 481.22 Td (\(131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.65 481.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.45 481.17 Td (\(2.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.30 481.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.30 481.22 Td (\(131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 481.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 481.17 Td (\(2.2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 481.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.30 481.22 Td (\(55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 481.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.45 481.17 Td (\(2.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.30 481.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 468.17 Td (Domestic manufacturing deduction) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.30 468.22 Td (\(78) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.65 468.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.45 468.17 Td (\(1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.30 468.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.30 468.22 Td (\(122) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 468.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 468.17 Td (\(2.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 468.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.30 468.22 Td (\(17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.65 468.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.45 468.17 Td (\(0.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.30 468.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 455.17 Td (State and local taxes \(net of valuation allowance\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.65 455.17 Td (77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 375.80 455.17 Td (1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 455.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 455.17 Td (23) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 455.17 Td (0.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 455.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 455.17 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.80 455.17 Td (0.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 455.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 442.17 Td (Foreign and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.30 442.22 Td (\(93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.65 442.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.45 442.17 Td (\(1.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.30 442.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.30 442.22 Td (\(90) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 439.65 442.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.45 442.17 Td (\(1.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 442.17 Td (\)%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 442.17 Td (32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.80 442.17 Td (1.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 442.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 321.00 429.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.10 429.17 Td (4,156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.80 429.17 Td (81.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.65 429.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.00 429.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.10 429.17 Td (1,408) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 456.80 429.17 Td (23.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 429.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.00 429.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.65 429.17 Td (446) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 542.80 429.17 Td (21.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 563.65 429.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 402.10 Td (New ) Tj ET Q q 0 0 0 rg BT 57.56 402.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 72.45 402.10 Td (reform ) Tj ET Q q 0 0 0 rg BT 102.33 402.10 Td (legislation ) Tj ET Q q 0 0 0 rg BT 146.67 402.10 Td (in ) Tj ET Q q 0 0 0 rg BT 157.12 402.10 Td (the ) Tj ET Q q 0 0 0 rg BT 172.01 402.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 192.47 402.10 Td (was ) Tj ET Q q 0 0 0 rg BT 210.69 402.10 Td (enacted ) Tj ET Q q 0 0 0 rg BT 243.90 402.10 Td (on ) Tj ET Q q 0 0 0 rg BT 256.58 402.10 Td (December ) Tj ET Q q 0 0 0 rg BT 300.33 402.10 Td (22, ) Tj ET Q q 0 0 0 rg BT 315.51 402.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 338.18 402.10 Td (known ) Tj ET Q q 0 0 0 rg BT 368.08 402.10 Td (as ) Tj ET Q q 0 0 0 rg BT 379.09 402.10 Td (the ) Tj ET Q q 0 0 0 rg BT 393.78 402.10 Td (T) Tj ET Q q 0 0 0 rg BT 399.19 402.10 Td (ax ) Tj ET Q q 0 0 0 rg BT 411.31 402.10 Td (Cuts ) Tj ET Q q 0 0 0 rg BT 432.32 402.10 Td (and ) Tj ET Q q 0 0 0 rg BT 449.44 402.10 Td (Jobs ) Tj ET Q q 0 0 0 rg BT 469.30 402.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 486.42 402.10 Td (of ) Tj ET Q q 0 0 0 rg BT 497.42 402.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 520.10 402.10 Td (\(the ) Tj ET Q q 0 0 0 rg BT 537.73 402.10 Td (Act\). ) Tj ET Q q 0 0 0 rg BT 560.48 402.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 390.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 52.74 390.10 Td (moves ) Tj ET Q q 0 0 0 rg BT 81.16 390.10 Td (from ) Tj ET Q q 0 0 0 rg BT 102.90 390.10 Td (a ) Tj ET Q q 0 0 0 rg BT 109.64 390.10 Td (worldwide ) Tj ET Q q 0 0 0 rg BT 154.72 390.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 169.24 390.10 Td (system ) Tj ET Q q 0 0 0 rg BT 199.32 390.10 Td (to ) Tj ET Q q 0 0 0 rg BT 209.40 390.10 Td (a ) Tj ET Q q 0 0 0 rg BT 216.15 390.10 Td (quasi-territorial ) Tj ET Q q 0 0 0 rg BT 280.65 390.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 295.17 390.10 Td (system ) Tj ET Q q 0 0 0 rg BT 325.25 390.10 Td (and ) Tj ET Q q 0 0 0 rg BT 342.00 390.10 Td (comprises ) Tj ET Q q 0 0 0 rg BT 384.85 390.10 Td (broad ) Tj ET Q q 0 0 0 rg BT 409.92 390.10 Td (and ) Tj ET Q q 0 0 0 rg BT 426.66 390.10 Td (complex ) Tj ET Q q 0 0 0 rg BT 463.40 390.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 497.91 390.10 Td (to ) Tj ET Q q 0 0 0 rg BT 508.00 390.10 Td (the ) Tj ET Q q 0 0 0 rg BT 522.52 390.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 542.61 390.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 557.13 390.10 Td (code ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 378.10 Td (including, ) Tj ET Q q 0 0 0 rg BT 78.77 378.10 Td (but ) Tj ET Q q 0 0 0 rg BT 94.04 378.10 Td (not ) Tj ET Q q 0 0 0 rg BT 109.32 378.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 140.14 378.10 Td (to, ) Tj ET Q q 0 0 0 rg BT 152.91 378.10 Td (\(1\) ) Tj ET Q q 0 0 0 rg BT 167.07 378.10 Td (reducing ) Tj ET Q q 0 0 0 rg BT 204.55 378.10 Td (the ) Tj ET Q q 0 0 0 rg BT 219.26 378.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 239.54 378.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 254.25 378.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 271.73 378.10 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 293.67 378.10 Td (35%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.00 378.10 Td ( ) Tj ET Q q 0 0 0 rg BT 314.49 378.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 324.76 378.10 Td (21%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.09 378.10 Td (; ) Tj ET Q q 0 0 0 rg BT 348.37 378.10 Td (\(2\) ) Tj ET Q q 0 0 0 rg BT 362.52 378.10 Td (adding ) Tj ET Q q 0 0 0 rg BT 392.24 378.10 Td (a ) Tj ET Q q 0 0 0 rg BT 399.17 378.10 Td (deemed ) Tj ET Q q 0 0 0 rg BT 432.76 378.10 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 481.34 378.10 Td (transition ) Tj ET Q q 0 0 0 rg BT 521.61 378.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 536.32 378.10 Td (on ) Tj ET Q q 0 0 0 rg BT 548.82 378.10 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 366.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 67.66 366.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 104.33 366.10 Td (and ) Tj ET Q q 0 0 0 rg BT 121.55 366.10 Td (profits; ) Tj ET Q q 0 0 0 rg BT 153.23 366.10 Td (\(3\) ) Tj ET Q q 0 0 0 rg BT 167.67 366.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 207.66 366.10 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 256.00 366.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 276.57 366.10 Td (federal ) Tj ET Q q 0 0 0 rg BT 307.11 366.10 Td (income ) Tj ET Q q 0 0 0 rg BT 339.33 366.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 362.66 366.10 Td (on ) Tj ET Q q 0 0 0 rg BT 375.45 366.10 Td (dividends ) Tj ET Q q 0 0 0 rg BT 417.13 366.10 Td (from ) Tj ET Q q 0 0 0 rg BT 439.35 366.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 471.01 366.10 Td (subsidiaries; ) Tj ET Q q 0 0 0 rg BT 523.80 366.10 Td (\(4\) ) Tj ET Q q 0 0 0 rg BT 538.24 366.10 Td (including ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 354.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 66.10 354.10 Td (income ) Tj ET Q q 0 0 0 rg BT 98.42 354.10 Td (of ) Tj ET Q q 0 0 0 rg BT 109.65 354.10 Td (controlled ) Tj ET Q q 0 0 0 rg BT 153.08 354.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 184.85 354.10 Td (companies ) Tj ET Q q 0 0 0 rg BT 230.51 354.10 Td (in ) Tj ET Q q 0 0 0 rg BT 241.18 354.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 261.85 354.10 Td (taxable ) Tj ET Q q 0 0 0 rg BT 293.62 354.10 Td (income; ) Tj ET Q q 0 0 0 rg BT 328.72 354.10 Td (\(5\) ) Tj ET Q q 0 0 0 rg BT 343.28 354.10 Td (creating ) Tj ET Q q 0 0 0 rg BT 378.37 354.10 Td (a ) Tj ET Q q 0 0 0 rg BT 385.70 354.10 Td (new ) Tj ET Q q 0 0 0 rg BT 405.26 354.10 Td (minimum ) Tj ET Q q 0 0 0 rg BT 447.04 354.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 462.15 354.10 Td (referred ) Tj ET Q q 0 0 0 rg BT 496.68 354.10 Td (to ) Tj ET Q q 0 0 0 rg BT 507.35 354.10 Td (as ) Tj ET Q q 0 0 0 rg BT 518.58 354.10 Td (a ) Tj ET Q q 0 0 0 rg BT 525.91 354.10 Td (base ) Tj ET Q q 0 0 0 rg BT 546.57 354.10 Td (erosion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 342.10 Td (anti-abuse ) Tj ET Q q 0 0 0 rg BT 79.59 342.10 Td (income ) Tj ET Q q 0 0 0 rg BT 111.53 342.10 Td (tax; ) Tj ET Q q 0 0 0 rg BT 129.02 342.10 Td (\(6\) ) Tj ET Q q 0 0 0 rg BT 143.18 342.10 Td (limiting ) Tj ET Q q 0 0 0 rg BT 177.35 342.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 207.05 342.10 Td (research-based ) Tj ET Q q 0 0 0 rg BT 268.96 342.10 Td (credits; ) Tj ET Q q 0 0 0 rg BT 300.89 342.10 Td (and ) Tj ET Q q 0 0 0 rg BT 317.83 342.10 Td (\(7\) ) Tj ET Q q 0 0 0 rg BT 331.99 342.10 Td (eliminating ) Tj ET Q q 0 0 0 rg BT 380.04 342.10 Td (the ) Tj ET Q q 0 0 0 rg BT 394.75 342.10 Td (domestic ) Tj ET Q q 0 0 0 rg BT 433.36 342.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 494.17 342.10 Td (deduction.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 318.10 Td (Although ) Tj ET Q q 0 0 0 rg BT 75.94 318.10 Td (many ) Tj ET Q q 0 0 0 rg BT 100.31 318.10 Td (aspects ) Tj ET Q q 0 0 0 rg BT 131.35 318.10 Td (of ) Tj ET Q q 0 0 0 rg BT 141.84 318.10 Td (the ) Tj ET Q q 0 0 0 rg BT 155.74 318.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 172.34 318.10 Td (are ) Tj ET Q q 0 0 0 rg BT 186.71 318.10 Td (not ) Tj ET Q q 0 0 0 rg BT 201.64 318.10 Td (ef) Tj ET Q q 0 0 0 rg BT 209.23 318.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 238.59 318.10 Td (until ) Tj ET Q q 0 0 0 rg BT 259.09 318.10 Td (2018, ) Tj ET Q q 0 0 0 rg BT 283.75 318.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 325.90 318.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 340.27 318.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 374.64 318.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 385.13 318.10 Td ($2.9 ) Tj ET Q q 0 0 0 rg BT 404.79 318.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.90 318.10 Td ( ) Tj ET Q q 0 0 0 rg BT 433.06 318.10 Td (was ) Tj ET Q q 0 0 0 rg BT 450.77 318.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 496.80 318.10 Td (in ) Tj ET Q q 0 0 0 rg BT 506.73 318.10 Td (the ) Tj ET Q q 0 0 0 rg BT 521.11 318.10 Td (fourth ) Tj ET Q q 0 0 0 rg BT 547.71 318.10 Td (quarter ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 306.10 Td (of ) Tj ET Q q 0 0 0 rg BT 45.75 306.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 67.17 306.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 88.58 306.10 Td (enactment ) Tj ET Q q 0 0 0 rg BT 131.09 306.10 Td (of ) Tj ET Q q 0 0 0 rg BT 140.84 306.10 Td (the ) Tj ET Q q 0 0 0 rg BT 154.16 306.10 Td (Act. ) Tj ET Q q 0 0 0 rg BT 172.41 306.10 Td (The ) Tj ET Q q 0 0 0 rg BT 189.38 306.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 230.78 306.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 264.41 306.10 Td (included ) Tj ET Q q 0 0 0 rg BT 300.26 306.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 306.11 306.10 Td ($2.6 ) Tj ET Q q 0 0 0 rg BT 325.03 306.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 351.15 306.10 Td ( ) Tj ET Q q 0 0 0 rg BT 352.56 306.10 Td (one-time ) Tj ET Q q 0 0 0 rg BT 389.52 306.10 Td (deemed ) Tj ET Q q 0 0 0 rg BT 422.03 306.10 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 469.54 306.10 Td (transition ) Tj ET Q q 0 0 0 rg BT 508.73 306.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 522.37 306.10 Td (on ) Tj ET Q q 0 0 0 rg BT 533.78 306.10 Td (previously ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 294.10 Td (untaxed ) Tj ET Q q 0 0 0 rg BT 69.96 294.10 Td (post-1986 ) Tj ET Q q 0 0 0 rg BT 112.27 294.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 143.46 294.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 179.65 294.10 Td (and ) Tj ET Q q 0 0 0 rg BT 196.40 294.10 Td (profits ) Tj ET Q q 0 0 0 rg BT 224.81 294.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 268.23 294.10 Td (related ) Tj ET Q q 0 0 0 rg BT 297.74 294.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 312.26 294.10 Td (reserves\). ) Tj ET Q q 0 0 0 rg BT 353.00 294.10 Td (Those ) Tj ET Q q 0 0 0 rg BT 379.74 294.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 415.93 294.10 Td (were ) Tj ET Q q 0 0 0 rg BT 437.67 294.10 Td (ef) Tj ET Q q 0 0 0 rg BT 445.26 294.10 Td (fectively ) Tj ET Q q 0 0 0 rg BT 482.55 294.10 Td (taxed ) Tj ET Q q 0 0 0 rg BT 506.51 294.10 Td (at ) Tj ET Q q 0 0 0 rg BT 516.04 294.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.79 294.10 Td (15.5%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 548.62 294.10 Td ( ) Tj ET Q q 0 0 0 rg BT 550.93 294.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 568.22 294.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 282.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.09 282.10 Td (extent ) Tj ET Q q 0 0 0 rg BT 76.41 282.10 Td (that ) Tj ET Q q 0 0 0 rg BT 93.28 282.10 Td (the ) Tj ET Q q 0 0 0 rg BT 107.37 282.10 Td (specified ) Tj ET Q q 0 0 0 rg BT 145.34 282.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 176.10 282.10 Td (corporations ) Tj ET Q q 0 0 0 rg BT 227.96 282.10 Td (held ) Tj ET Q q 0 0 0 rg BT 247.05 282.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 266.70 282.10 Td (and ) Tj ET Q q 0 0 0 rg BT 283.02 282.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 312.10 282.10 Td (other ) Tj ET Q q 0 0 0 rg BT 334.52 282.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 359.73 282.10 Td (and ) Tj ET Q q 0 0 0 rg BT 376.04 282.10 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.36 282.10 Td (8.0%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.19 282.10 Td ( ) Tj ET Q q 0 0 0 rg BT 410.07 282.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 426.93 282.10 Td (on ) Tj ET Q q 0 0 0 rg BT 438.81 282.10 Td (the ) Tj ET Q q 0 0 0 rg BT 452.90 282.10 Td (remaining ) Tj ET Q q 0 0 0 rg BT 495.32 282.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 531.08 282.10 Td (and ) Tj ET Q q 0 0 0 rg BT 547.39 282.10 Td (profits. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 270.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 270.10 Td (remaining ) Tj ET Q q 0 0 0 rg BT 97.09 270.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 139.58 270.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 154.30 270.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 189.00 270.10 Td (included ) Tj ET Q q 0 0 0 rg BT 225.94 270.10 Td (an ) Tj ET Q q 0 0 0 rg BT 237.88 270.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 284.26 270.10 Td (to ) Tj ET Q q 0 0 0 rg BT 294.54 270.10 Td (measure ) Tj ET Q q 0 0 0 rg BT 330.35 270.10 Td (net ) Tj ET Q q 0 0 0 rg BT 345.07 270.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 380.87 270.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 395.59 270.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 421.42 270.10 Td (at ) Tj ET Q q 0 0 0 rg BT 431.14 270.10 Td (the ) Tj ET Q q 0 0 0 rg BT 445.85 270.10 Td (new ) Tj ET Q q 0 0 0 rg BT 465.01 270.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 485.30 270.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 500.01 270.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 517.50 270.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.33 270.10 Td (21%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.66 270.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 246.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.90 246.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 100.12 246.10 Td (for ) Tj ET Q q 0 0 0 rg BT 114.13 246.10 Td (the ) Tj ET Q q 0 0 0 rg BT 128.70 246.10 Td (reduction ) Tj ET Q q 0 0 0 rg BT 168.81 246.10 Td (of ) Tj ET Q q 0 0 0 rg BT 179.50 246.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 215.15 246.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 229.72 246.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 255.40 246.10 Td (to ) Tj ET Q q 0 0 0 rg BT 265.53 246.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 280.10 246.10 Td (21%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.43 246.10 Td ( ) Tj ET Q q 0 0 0 rg BT 300.78 246.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 315.35 246.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 332.68 246.10 Td (is ) Tj ET Q q 0 0 0 rg BT 341.71 246.10 Td (complete. ) Tj ET Q q 0 0 0 rg BT 383.04 246.10 Td (The ) Tj ET Q q 0 0 0 rg BT 400.94 246.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 415.50 246.10 Td (char) Tj ET Q q 0 0 0 rg BT 432.53 246.10 Td (ge ) Tj ET Q q 0 0 0 rg BT 444.32 246.10 Td (for ) Tj ET Q q 0 0 0 rg BT 458.33 246.10 Td (the ) Tj ET Q q 0 0 0 rg BT 472.90 246.10 Td (deemed ) Tj ET Q q 0 0 0 rg BT 506.34 246.10 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 554.78 246.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 569.35 246.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 234.10 Td (incomplete, ) Tj ET Q q 0 0 0 rg BT 84.94 234.10 Td (but ) Tj ET Q q 0 0 0 rg BT 99.73 234.10 Td (was ) Tj ET Q q 0 0 0 rg BT 117.29 234.10 Td (recorded ) Tj ET Q q 0 0 0 rg BT 154.27 234.10 Td (as ) Tj ET Q q 0 0 0 rg BT 164.61 234.10 Td (a ) Tj ET Q q 0 0 0 rg BT 171.06 234.10 Td (provisional ) Tj ET Q q 0 0 0 rg BT 218.06 234.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 250.07 234.10 Td (as ) Tj ET Q q 0 0 0 rg BT 260.41 234.10 Td (we ) Tj ET Q q 0 0 0 rg BT 274.08 234.10 Td (were ) Tj ET Q q 0 0 0 rg BT 295.51 234.10 Td (able ) Tj ET Q q 0 0 0 rg BT 314.18 234.10 Td (to ) Tj ET Q q 0 0 0 rg BT 323.97 234.10 Td (make ) Tj ET Q q 0 0 0 rg BT 347.63 234.10 Td (a ) Tj ET Q q 0 0 0 rg BT 354.08 234.10 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 398.84 234.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 434.17 234.10 Td (of ) Tj ET Q q 0 0 0 rg BT 444.51 234.10 Td (this ) Tj ET Q q 0 0 0 rg BT 460.97 234.10 Td (tax. ) Tj ET Q q 0 0 0 rg BT 477.55 234.10 Td (The ) Tj ET Q q 0 0 0 rg BT 495.11 234.10 Td (provisional ) Tj ET Q q 0 0 0 rg BT 542.11 234.10 Td (amounts ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 222.10 Td (may ) Tj ET Q q 0 0 0 rg BT 55.27 222.10 Td (change ) Tj ET Q q 0 0 0 rg BT 85.64 222.10 Td (when ) Tj ET Q q 0 0 0 rg BT 109.36 222.10 Td (completed ) Tj ET Q q 0 0 0 rg BT 153.07 222.10 Td (in ) Tj ET Q q 0 0 0 rg BT 162.90 222.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 184.96 222.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 207.01 222.10 Td (finalizing ) Tj ET Q q 0 0 0 rg BT 247.39 222.10 Td (untaxed ) Tj ET Q q 0 0 0 rg BT 281.10 222.10 Td (post-1986 ) Tj ET Q q 0 0 0 rg BT 323.15 222.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 354.09 222.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 390.02 222.10 Td (and ) Tj ET Q q 0 0 0 rg BT 406.51 222.10 Td (profits ) Tj ET Q q 0 0 0 rg BT 434.68 222.10 Td (and ) Tj ET Q q 0 0 0 rg BT 451.17 222.10 Td (related ) Tj ET Q q 0 0 0 rg BT 480.43 222.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 500.25 222.10 Td (and ) Tj ET Q q 0 0 0 rg BT 516.75 222.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 546.00 222.10 Td (eligible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 210.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 61.83 210.10 Td (of ) Tj ET Q q 0 0 0 rg BT 72.67 210.10 Td (the ) Tj ET Q q 0 0 0 rg BT 87.39 210.10 Td (specified ) Tj ET Q q 0 0 0 rg BT 125.99 210.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 157.37 210.10 Td (corporations. ) Tj ET Q q 0 0 0 rg BT 212.18 210.10 Td (The ) Tj ET Q q 0 0 0 rg BT 230.23 210.10 Td (provisional ) Tj ET Q q 0 0 0 rg BT 277.73 210.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 314.12 210.10 Td (may ) Tj ET Q q 0 0 0 rg BT 333.84 210.10 Td (also ) Tj ET Q q 0 0 0 rg BT 352.45 210.10 Td (change ) Tj ET Q q 0 0 0 rg BT 383.27 210.10 Td (if ) Tj ET Q q 0 0 0 rg BT 391.88 210.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 434.37 210.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 472.97 210.10 Td (of ) Tj ET Q q 0 0 0 rg BT 483.81 210.10 Td (the ) Tj ET Q q 0 0 0 rg BT 498.53 210.10 Td (relevant ) Tj ET Q q 0 0 0 rg BT 533.23 210.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 547.95 210.10 Td (code ) Tj ET Q q 0 0 0 rg BT 569.33 210.10 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 198.10 Td (released.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 174.10 Td (Earnings ) Tj ET Q q 0 0 0 rg BT 72.83 174.10 Td (for ) Tj ET Q q 0 0 0 rg BT 85.77 174.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 114.25 174.10 Td (of ) Tj ET Q q 0 0 0 rg BT 123.86 174.10 Td (our ) Tj ET Q q 0 0 0 rg BT 138.47 174.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 198.06 174.10 Td (operations ) Tj ET Q q 0 0 0 rg BT 241.00 174.10 Td (in ) Tj ET Q q 0 0 0 rg BT 250.06 174.10 Td (low ) Tj ET Q q 0 0 0 rg BT 266.34 174.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 279.84 174.10 Td (jurisdictions, ) Tj ET Q q 0 0 0 rg BT 333.06 174.10 Td (such ) Tj ET Q q 0 0 0 rg BT 352.67 174.10 Td (as ) Tj ET Q q 0 0 0 rg BT 362.28 174.10 Td (Switzerland, ) Tj ET Q q 0 0 0 rg BT 413.83 174.10 Td (Ireland ) Tj ET Q q 0 0 0 rg BT 443.42 174.10 Td (and ) Tj ET Q q 0 0 0 rg BT 459.14 174.10 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 486.53 174.10 Td (Rico, ) Tj ET Q q 0 0 0 rg BT 509.20 174.10 Td (were ) Tj ET Q q 0 0 0 rg BT 529.91 174.10 Td (indefinitely ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 162.10 Td (reinvested ) Tj ET Q q 0 0 0 rg BT 79.87 162.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 102.08 162.10 Td (to ) Tj ET Q q 0 0 0 rg BT 112.64 162.10 Td (the ) Tj ET Q q 0 0 0 rg BT 127.63 162.10 Td (enactment ) Tj ET Q q 0 0 0 rg BT 171.50 162.10 Td (of ) Tj ET Q q 0 0 0 rg BT 182.60 162.10 Td (the ) Tj ET Q q 0 0 0 rg BT 196.98 162.10 Td (Act. ) Tj ET Q q 0 0 0 rg BT 216.70 162.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 240.59 162.10 Td (operates ) Tj ET Q q 0 0 0 rg BT 276.69 162.10 Td (under ) Tj ET Q q 0 0 0 rg BT 302.23 162.10 Td (a ) Tj ET Q q 0 0 0 rg BT 309.44 162.10 Td (favorable ) Tj ET Q q 0 0 0 rg BT 349.97 162.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 364.97 162.10 Td (grant ) Tj ET Q q 0 0 0 rg BT 388.29 162.10 Td (in ) Tj ET Q q 0 0 0 rg BT 398.84 162.10 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 427.73 162.10 Td (Rico ) Tj ET Q q 0 0 0 rg BT 449.39 162.10 Td (not ) Tj ET Q q 0 0 0 rg BT 464.95 162.10 Td (scheduled ) Tj ET Q q 0 0 0 rg BT 507.71 162.10 Td (to ) Tj ET Q q 0 0 0 rg BT 518.26 162.10 Td (expire ) Tj ET Q q 0 0 0 rg BT 546.02 162.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 568.24 162.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 150.10 Td (2023.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 126.10 Td (As ) Tj ET Q q 0 0 0 rg BT 49.38 126.10 Td (a ) Tj ET Q q 0 0 0 rg BT 56.08 126.10 Td (result ) Tj ET Q q 0 0 0 rg BT 80.56 126.10 Td (of ) Tj ET Q q 0 0 0 rg BT 91.15 126.10 Td (the ) Tj ET Q q 0 0 0 rg BT 105.63 126.10 Td (transition ) Tj ET Q q 0 0 0 rg BT 145.67 126.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 160.15 126.10 Td (under ) Tj ET Q q 0 0 0 rg BT 185.18 126.10 Td (the ) Tj ET Q q 0 0 0 rg BT 199.16 126.10 Td (Act, ) Tj ET Q q 0 0 0 rg BT 218.36 126.10 Td (the ) Tj ET Q q 0 0 0 rg BT 232.84 126.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 273.99 126.10 Td (is ) Tj ET Q q 0 0 0 rg BT 282.92 126.10 Td (no ) Tj ET Q q 0 0 0 rg BT 295.19 126.10 Td (longer ) Tj ET Q q 0 0 0 rg BT 323.00 126.10 Td (indefinitely ) Tj ET Q q 0 0 0 rg BT 371.36 126.10 Td (reinvested ) Tj ET Q q 0 0 0 rg BT 414.72 126.10 Td (with ) Tj ET Q q 0 0 0 rg BT 434.76 126.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 465.34 126.10 Td (to ) Tj ET Q q 0 0 0 rg BT 475.38 126.10 Td (its ) Tj ET Q q 0 0 0 rg BT 487.09 126.10 Td (undistributed ) Tj ET Q q 0 0 0 rg BT 542.13 126.10 Td (earnings ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 114.10 Td (from ) Tj ET Q q 0 0 0 rg BT 57.64 114.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 88.72 114.10 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 138.14 114.10 Td (and ) Tj ET Q q 0 0 0 rg BT 154.78 114.10 Td (has ) Tj ET Q q 0 0 0 rg BT 170.31 114.10 Td (provided ) Tj ET Q q 0 0 0 rg BT 208.06 114.10 Td (a ) Tj ET Q q 0 0 0 rg BT 214.70 114.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 250.21 114.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 264.63 114.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 297.94 114.10 Td (or ) Tj ET Q q 0 0 0 rg BT 308.47 114.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 339.55 114.10 Td (and ) Tj ET Q q 0 0 0 rg BT 356.19 114.10 Td (state ) Tj ET Q q 0 0 0 rg BT 376.72 114.10 Td (income ) Tj ET Q q 0 0 0 rg BT 408.35 114.10 Td (and ) Tj ET Q q 0 0 0 rg BT 424.99 114.10 Td (withholding ) Tj ET Q q 0 0 0 rg BT 475.53 114.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 489.95 114.10 Td (that ) Tj ET Q q 0 0 0 rg BT 507.15 114.10 Td (would ) Tj ET Q q 0 0 0 rg BT 534.35 114.10 Td (apply) Tj ET Q q 0 0 0 rg BT 555.92 114.10 Td (. ) Tj ET Q q 0 0 0 rg BT 560.46 114.10 Td (The ) Tj ET Q q 0 0 0 rg BT 578.51 114.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 102.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 77.32 102.10 Td (remains ) Tj ET Q q 0 0 0 rg BT 111.42 102.10 Td (indefinitely ) Tj ET Q q 0 0 0 rg BT 159.95 102.10 Td (reinvested ) Tj ET Q q 0 0 0 rg BT 203.48 102.10 Td (with ) Tj ET Q q 0 0 0 rg BT 223.70 102.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 254.45 102.10 Td (to ) Tj ET Q q 0 0 0 rg BT 264.66 102.10 Td (its ) Tj ET Q q 0 0 0 rg BT 276.55 102.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 313.96 102.10 Td (statement ) Tj ET Q q 0 0 0 rg BT 354.72 102.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 377.16 102.10 Td (in ) Tj ET Q q 0 0 0 rg BT 387.37 102.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 415.91 102.10 Td (of ) Tj ET Q q 0 0 0 rg BT 426.67 102.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 441.33 102.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 463.76 102.10 Td (of ) Tj ET Q q 0 0 0 rg BT 474.53 102.10 Td (its ) Tj ET Q q 0 0 0 rg BT 486.42 102.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 517.73 102.10 Td (subsidiaries. ) Tj ET Q q 0 0 0 rg BT 569.34 102.10 Td (A) Tj ET Q q 0 0 0 rg BT 576.01 102.10 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 90.10 Td (determination ) Tj ET Q q 0 0 0 rg BT 94.04 90.10 Td (of ) Tj ET Q q 0 0 0 rg BT 104.87 90.10 Td (the ) Tj ET Q q 0 0 0 rg BT 119.58 90.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 155.39 90.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 170.11 90.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 203.71 90.10 Td (with ) Tj ET Q q 0 0 0 rg BT 223.99 90.10 Td (respect ) Tj ET Q q 0 0 0 rg BT 254.81 90.10 Td (to ) Tj ET Q q 0 0 0 rg BT 265.09 90.10 Td (this ) Tj ET Q q 0 0 0 rg BT 282.04 90.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 304.54 90.10 Td (dif) Tj ET Q q 0 0 0 rg BT 315.46 90.10 Td (ference ) Tj ET Q q 0 0 0 rg BT 347.38 90.10 Td (is ) Tj ET Q q 0 0 0 rg BT 356.55 90.10 Td (not ) Tj ET Q q 0 0 0 rg BT 371.83 90.10 Td (practicable.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 66.10 Td (V) Tj ET Q q 0 0 0 rg BT 42.11 66.10 Td (aluation ) Tj ET Q q 0 0 0 rg BT 76.95 66.10 Td (allowances ) Tj ET Q q 0 0 0 rg BT 123.99 66.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 164.93 66.10 Td (to ) Tj ET Q q 0 0 0 rg BT 175.33 66.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 204.60 66.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 222.79 66.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 281.49 66.10 Td (were ) Tj ET Q q 0 0 0 rg BT 303.54 66.10 Td (released ) Tj ET Q q 0 0 0 rg BT 338.91 66.10 Td (in ) Tj ET Q q 0 0 0 rg BT 349.31 66.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 371.93 66.10 Td (following ) Tj ET Q q 0 0 0 rg BT 413.44 66.10 Td (the ) Tj ET Q q 0 0 0 rg BT 428.28 66.10 Td (divestiture ) Tj ET Q q 0 0 0 rg BT 473.11 66.10 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 484.06 66.10 Td (Recothr) Tj ET Q q 0 0 0 rg BT 515.35 66.10 Td (om*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.57 66.10 Td (, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 537.69 66.10 Td (Ixempra*) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 54.10 Td (and ) Tj ET Q q 0 0 0 rg BT 52.38 54.10 Td (other ) Tj ET Q q 0 0 0 rg BT 74.86 54.10 Td (mature ) Tj ET Q q 0 0 0 rg BT 104.56 54.10 Td (brands. ) Tj ET Q q 0 0 0 rg BT 135.66 54.10 Td (Goodwill ) Tj ET Q q 0 0 0 rg BT 175.38 54.10 Td (allocated ) Tj ET Q q 0 0 0 rg BT 213.40 54.10 Td (to ) Tj ET Q q 0 0 0 rg BT 223.12 54.10 Td (business ) Tj ET Q q 0 0 0 rg BT 258.95 54.10 Td (divestitures ) Tj ET Q q 0 0 0 rg BT 306.99 54.10 Td (as ) Tj ET Q q 0 0 0 rg BT 317.25 54.10 Td (well ) Tj ET Q q 0 0 0 rg BT 336.41 54.10 Td (as ) Tj ET Q q 0 0 0 rg BT 346.68 54.10 Td (the ) Tj ET Q q 0 0 0 rg BT 360.83 54.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 380.55 54.10 Td (Branded ) Tj ET Q q 0 0 0 rg BT 416.37 54.10 Td (Prescription ) Tj ET Q q 0 0 0 rg BT 466.63 54.10 Td (Drug ) Tj ET Q q 0 0 0 rg BT 489.12 54.10 Td (Fee ) Tj ET Q q 0 0 0 rg BT 505.49 54.10 Td (are ) Tj ET Q q 0 0 0 rg BT 519.64 54.10 Td (not ) Tj ET Q q 0 0 0 rg BT 534.35 54.10 Td (deductible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 42.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 42.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 64.88 42.10 Td (purposes. ) Tj ET Q endstream endobj 165 0 obj <> endobj 166 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (82) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (R&D ) Tj ET Q q 0 0 0 rg BT 60.88 737.10 Td (char) Tj ET Q q 0 0 0 rg BT 77.90 737.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 94.44 737.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 134.86 737.10 Td (from ) Tj ET Q q 0 0 0 rg BT 157.50 737.10 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 204.59 737.10 Td (related ) Tj ET Q q 0 0 0 rg BT 235.00 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 252.65 737.10 Td (milestone ) Tj ET Q q 0 0 0 rg BT 294.74 737.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 336.27 737.10 Td (to ) Tj ET Q q 0 0 0 rg BT 347.25 737.10 Td (former ) Tj ET Q q 0 0 0 rg BT 377.67 737.10 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 431.41 737.10 Td (are ) Tj ET Q q 0 0 0 rg BT 446.83 737.10 Td (not ) Tj ET Q q 0 0 0 rg BT 462.81 737.10 Td (deductible ) Tj ET Q q 0 0 0 rg BT 507.67 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 522.54 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 537.96 737.10 Td (purposes. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (These ) Tj ET Q q 0 0 0 rg BT 62.38 725.10 Td (include ) Tj ET Q q 0 0 0 rg BT 94.31 725.10 Td (Flexus, ) Tj ET Q q 0 0 0 rg BT 125.98 725.10 Td (Cardioxyl ) Tj ET Q q 0 0 0 rg BT 168.48 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 185.41 725.10 Td (IFM ) Tj ET Q q 0 0 0 rg BT 205.70 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 215.98 725.10 Td (2017; ) Tj ET Q q 0 0 0 rg BT 241.25 725.10 Td (Flexus, ) Tj ET Q q 0 0 0 rg BT 272.92 725.10 Td (Padlock ) Tj ET Q q 0 0 0 rg BT 307.64 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 324.58 725.10 Td (Cormorant ) Tj ET Q q 0 0 0 rg BT 370.40 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 380.68 725.10 Td (2016; ) Tj ET Q q 0 0 0 rg BT 405.96 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 422.90 725.10 Td (Flexus ) Tj ET Q q 0 0 0 rg BT 452.07 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 469.01 725.10 Td (Cardioxyl ) Tj ET Q q 0 0 0 rg BT 511.50 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 521.78 725.10 Td (2015. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 64.36 701.10 Td (Rico ) Tj ET Q q 0 0 0 rg BT 85.49 701.10 Td (imposes ) Tj ET Q q 0 0 0 rg BT 120.52 701.10 Td (an ) Tj ET Q q 0 0 0 rg BT 132.21 701.10 Td (excise ) Tj ET Q q 0 0 0 rg BT 159.44 701.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 173.91 701.10 Td (on ) Tj ET Q q 0 0 0 rg BT 186.15 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 200.62 701.10 Td (gross ) Tj ET Q q 0 0 0 rg BT 223.98 701.10 Td (company ) Tj ET Q q 0 0 0 rg BT 262.88 701.10 Td (purchase ) Tj ET Q q 0 0 0 rg BT 300.67 701.10 Td (price ) Tj ET Q q 0 0 0 rg BT 322.90 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 333.48 701.10 Td (goods ) Tj ET Q q 0 0 0 rg BT 359.62 701.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 378.54 701.10 Td (from ) Tj ET Q q 0 0 0 rg BT 400.23 701.10 Td (our ) Tj ET Q q 0 0 0 rg BT 415.81 701.10 Td (manufacturer ) Tj ET Q q 0 0 0 rg BT 471.36 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 481.38 701.10 Td (Puerto ) Tj ET Q q 0 0 0 rg BT 509.74 701.10 Td (Rico. ) Tj ET Q q 0 0 0 rg BT 533.21 701.10 Td (The ) Tj ET Q q 0 0 0 rg BT 551.01 701.10 Td (excise ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.37 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 59.20 689.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 105.22 689.10 Td (in ) Tj ET Q q 0 0 0 rg BT 115.15 689.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 133.41 689.10 Td (of ) Tj ET Q q 0 0 0 rg BT 143.90 689.10 Td (products ) Tj ET Q q 0 0 0 rg BT 180.49 689.10 Td (sold ) Tj ET Q q 0 0 0 rg BT 199.32 689.10 Td (when ) Tj ET Q q 0 0 0 rg BT 223.14 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 237.51 689.10 Td (intra-entity ) Tj ET Q q 0 0 0 rg BT 284.09 689.10 Td (sale ) Tj ET Q q 0 0 0 rg BT 301.80 689.10 Td (occurs. ) Tj ET Q q 0 0 0 rg BT 332.55 689.10 Td (For ) Tj ET Q q 0 0 0 rg BT 348.60 689.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 368.54 689.10 Td (income ) Tj ET Q q 0 0 0 rg BT 400.13 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 414.50 689.10 Td (purposes, ) Tj ET Q q 0 0 0 rg BT 454.71 689.10 Td (the ) Tj ET Q q 0 0 0 rg BT 469.08 689.10 Td (excise ) Tj ET Q q 0 0 0 rg BT 496.22 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 510.59 689.10 Td (is ) Tj ET Q q 0 0 0 rg BT 519.42 689.10 Td (not ) Tj ET Q q 0 0 0 rg BT 534.35 689.10 Td (deductible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (but ) Tj ET Q q 0 0 0 rg BT 50.82 677.10 Td (results ) Tj ET Q q 0 0 0 rg BT 78.97 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 88.79 677.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 119.71 677.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 133.97 677.10 Td (credits ) Tj ET Q q 0 0 0 rg BT 162.67 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 179.71 677.10 Td (are ) Tj ET Q q 0 0 0 rg BT 193.96 677.10 Td (generally ) Tj ET Q q 0 0 0 rg BT 233.20 677.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 279.11 677.10 Td (in ) Tj ET Q q 0 0 0 rg BT 288.93 677.10 Td (our ) Tj ET Q q 0 0 0 rg BT 304.30 677.10 Td (provision ) Tj ET Q q 0 0 0 rg BT 344.12 677.10 Td (for ) Tj ET Q q 0 0 0 rg BT 357.82 677.10 Td (income ) Tj ET Q q 0 0 0 rg BT 389.30 677.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 411.89 677.10 Td (when ) Tj ET Q q 0 0 0 rg BT 435.59 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 449.85 677.10 Td (excise ) Tj ET Q q 0 0 0 rg BT 476.88 677.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 491.14 677.10 Td (is ) Tj ET Q q 0 0 0 rg BT 499.85 677.10 Td (incurred. ) Tj ET Q q 0 0 0 rg BT 537.71 677.10 Td (Increased ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 96.81 665.10 Td (activities ) Tj ET Q q 0 0 0 rg BT 135.41 665.10 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 149.57 665.10 Td (Opdivo) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 179.01 665.10 Td ( ) Tj ET Q q 0 0 0 rg BT 181.51 665.10 Td (resulted ) Tj ET Q q 0 0 0 rg BT 215.66 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 225.94 665.10 Td (the ) Tj ET Q q 0 0 0 rg BT 240.66 665.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 268.71 665.10 Td (domestic ) Tj ET Q q 0 0 0 rg BT 307.31 665.10 Td (manufacturing ) Tj ET Q q 0 0 0 rg BT 368.12 665.10 Td (deduction ) Tj ET Q q 0 0 0 rg BT 410.05 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 420.33 665.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 442.83 665.10 Td (compared ) Tj ET Q q 0 0 0 rg BT 484.75 665.10 Td (to ) Tj ET Q q 0 0 0 rg BT 495.03 665.10 Td (2015.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 642.30 Td (Deferr) Tj ET Q q 0 0 0 rg BT 62.29 642.30 Td (ed T) Tj ET Q q 0 0 0 rg BT 78.87 642.30 Td (axes and V) Tj ET Q q 0 0 0 rg BT 121.64 642.30 Td (aluation ) Tj ET Q q 0 0 0 rg BT 157.29 642.30 Td (Allowance) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 623.10 Td (The components of current and non-current deferred income tax assets/\(liabilities\) were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 586.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 586.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 586.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 586.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 586.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 560.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 560.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 560.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 560.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 560.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 534.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 534.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 534.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 534.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 534.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 508.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 508.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 508.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 508.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 508.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 482.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 482.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 482.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 482.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 482.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 456.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 456.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 456.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 456.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 456.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 430.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 430.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 430.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 430.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 430.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 404.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 404.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 404.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 404.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 404.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 378.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 378.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 378.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 378.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 378.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 352.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 352.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 352.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 352.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 352.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 326.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 326.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 326.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 326.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 326.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 300.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 300.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 300.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 300.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 300.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 274.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 274.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 274.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 274.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 274.60 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 248.60 373.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 248.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 248.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 248.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 248.60 80.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 599.6 m 492.5 599.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 492.5 599.6 m 496.5 599.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 599.6 m 576.5 599.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 586.6 m 492.5 586.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 586.6 m 576.5 586.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 430.6 m 492.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 430.6 m 576.5 430.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 404.6 m 492.5 404.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 404.6 m 576.5 404.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 326.6 m 492.5 326.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 326.6 m 576.5 326.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 313.6 m 492.5 313.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 313.6 m 576.5 313.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 301.6 m 492.5 301.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 299.6 m 492.5 299.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 301.6 m 576.5 301.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 299.6 m 576.5 299.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 248.60000000000002 m 492.5 248.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 248.60000000000002 m 576.5 248.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 236.60000000000002 m 492.5 236.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 234.60000000000002 m 492.5 234.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 236.60000000000002 m 576.5 236.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 234.60000000000002 m 576.5 234.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 603.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 471.25 603.83 Td (December) Tj ET Q q 0 0 0 rg BT 505.82 603.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 590.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.50 590.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.00 590.83 Td (2016) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 577.33 Td (Deferr) Tj ET Q q 0 0 0 rg BT 67.22 577.33 Td (ed tax assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 564.17 Td (Foreign net operating loss carryforwards) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 564.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 564.17 Td (2,872) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 564.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 564.17 Td (2,945) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 551.17 Td (State net operating loss and credit carryforwards) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 551.17 Td (143) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 551.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 551.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 538.17 Td (U.S. Federal net operating loss and credit carryforwards) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 538.17 Td (99) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 538.17 Td (156) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 525.17 Td (Deferred income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 525.17 Td (212) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 525.17 Td (764) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 512.17 Td (Milestone payments and license fees) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 512.17 Td (386) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 512.17 Td (534) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 499.17 Td (Pension and postretirement benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 499.17 Td (131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 499.17 Td (358) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 486.17 Td (Intercompany profit and other inventory items) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 486.17 Td (651) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 486.17 Td (1,241) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 473.17 Td (Other foreign deferred tax assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 473.17 Td (312) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 473.17 Td (188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 460.17 Td (Share-based compensation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 460.17 Td (60) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 460.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 460.17 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 447.17 Td (Internal transfer of intellectual property) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 447.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 447.17 Td (629) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 434.17 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 434.17 Td (280) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 434.17 Td (308) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 421.17 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 421.17 Td (otal deferred tax assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 421.17 Td (5,146) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 421.17 Td (7,351) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 408.17 Td (V) Tj ET Q q 0 0 0 rg BT 45.67 408.17 Td (aluation allowance) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.80 408.22 Td (\(2,827) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 408.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 408.17 Td (\(3,078) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 408.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 395.17 Td (Deferred tax assets net of valuation allowance) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 395.17 Td (2,319) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 395.17 Td (4,273) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 369.33 Td (Deferr) Tj ET Q q 0 0 0 rg BT 67.13 369.33 Td (ed tax liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 356.17 Td (Depreciation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 356.22 Td (\(1) Tj ET Q q 0 0 0 rg BT 483.63 356.22 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 356.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 356.17 Td (\(125) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 356.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 343.17 Td (Acquired intangible assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.30 343.22 Td (\(216) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 343.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 343.17 Td (\(344) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 343.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 330.17 Td (Goodwill and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.30 330.22 Td (\(527) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 330.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 330.17 Td (\(855) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 330.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 317.17 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 317.17 Td (otal deferred tax liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.30 317.22 Td (\(754) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 317.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 317.17 Td (\(1,324) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 317.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 304.17 Td (Deferred tax assets, net) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 304.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 304.17 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 304.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 304.17 Td (2,949) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 278.17 Td (Recognized as:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 265.17 Td (Deferred income taxes – non-current) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 265.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 265.17 Td (1,610) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 265.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 265.17 Td (2,996) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 252.17 Td (Income taxes payable – non-current) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 252.22 Td (\(45) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 252.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 252.17 Td (\(47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 252.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 239.17 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 239.17 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 239.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 239.17 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 239.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 239.17 Td (2,949) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 212.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.14 212.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 89.73 212.10 Td (of ) Tj ET Q q 0 0 0 rg BT 99.65 212.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 137.34 212.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 175.03 212.10 Td (for ) Tj ET Q q 0 0 0 rg BT 188.28 212.10 Td (intra-entity ) Tj ET Q q 0 0 0 rg BT 234.30 212.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 270.32 212.10 Td (of ) Tj ET Q q 0 0 0 rg BT 280.25 212.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 305.17 212.10 Td (other ) Tj ET Q q 0 0 0 rg BT 327.31 212.10 Td (than ) Tj ET Q q 0 0 0 rg BT 346.12 212.10 Td (inventory ) Tj ET Q q 0 0 0 rg BT 386.04 212.10 Td (resulted ) Tj ET Q q 0 0 0 rg BT 419.29 212.10 Td (in ) Tj ET Q q 0 0 0 rg BT 428.66 212.10 Td (net ) Tj ET Q q 0 0 0 rg BT 442.47 212.10 Td (reductions ) Tj ET Q q 0 0 0 rg BT 485.72 212.10 Td (to ) Tj ET Q q 0 0 0 rg BT 495.09 212.10 Td (prepaid ) Tj ET Q q 0 0 0 rg BT 526.67 212.10 Td (and ) Tj ET Q q 0 0 0 rg BT 542.70 212.10 Td (deferred ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 200.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.82 200.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 76.75 200.10 Td (pertaining ) Tj ET Q q 0 0 0 rg BT 119.90 200.10 Td (to ) Tj ET Q q 0 0 0 rg BT 130.28 200.10 Td (pre-2017 ) Tj ET Q q 0 0 0 rg BT 168.98 200.10 Td (internal ) Tj ET Q q 0 0 0 rg BT 202.12 200.10 Td (transfers ) Tj ET Q q 0 0 0 rg BT 239.15 200.10 Td (of ) Tj ET Q q 0 0 0 rg BT 250.09 200.10 Td (intellectual ) Tj ET Q q 0 0 0 rg BT 297.11 200.10 Td (property ) Tj ET Q q 0 0 0 rg BT 333.59 200.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.53 200.10 Td ($787 ) Tj ET Q q 0 0 0 rg BT 367.13 200.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 396.02 200.10 Td ( ) Tj ET Q q 0 0 0 rg BT 398.62 200.10 Td (and ) Tj ET Q q 0 0 0 rg BT 415.66 200.10 Td (were ) Tj ET Q q 0 0 0 rg BT 437.69 200.10 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 473.62 200.10 Td (through ) Tj ET Q q 0 0 0 rg BT 507.33 200.10 Td (retained ) Tj ET Q q 0 0 0 rg BT 542.14 200.10 Td (earnings ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 188.10 Td (as ) Tj ET Q q 0 0 0 rg BT 47.14 188.10 Td (a ) Tj ET Q q 0 0 0 rg BT 54.39 188.10 Td (cumulative ) Tj ET Q q 0 0 0 rg BT 101.63 188.10 Td (ef) Tj ET Q q 0 0 0 rg BT 109.22 188.10 Td (fect ) Tj ET Q q 0 0 0 rg BT 127.01 188.10 Td (of ) Tj ET Q q 0 0 0 rg BT 138.15 188.10 Td (an ) Tj ET Q q 0 0 0 rg BT 150.40 188.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 197.08 188.10 Td (change. ) Tj ET Q q 0 0 0 rg BT 230.09 188.10 Td (Additionally) Tj ET Q q 0 0 0 rg BT 279.99 188.10 Td (, ) Tj ET Q q 0 0 0 rg BT 285.30 188.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 324.20 188.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 363.11 188.10 Td (for ) Tj ET Q q 0 0 0 rg BT 377.58 188.10 Td (share-based ) Tj ET Q q 0 0 0 rg BT 427.58 188.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 464.83 188.10 Td (transactions ) Tj ET Q q 0 0 0 rg BT 515.40 188.10 Td (was ) Tj ET Q q 0 0 0 rg BT 533.76 188.10 Td (adopted ) Tj ET Q q 0 0 0 rg BT 568.23 188.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 176.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 58.26 176.10 Td (and ) Tj ET Q q 0 0 0 rg BT 74.95 176.10 Td (net ) Tj ET Q q 0 0 0 rg BT 89.43 176.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 117.78 176.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 132.26 176.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 166.17 176.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 176.76 176.10 Td ($39 ) Tj ET Q q 0 0 0 rg BT 194.01 176.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 222.91 176.10 Td ( ) Tj ET Q q 0 0 0 rg BT 225.16 176.10 Td (were ) Tj ET Q q 0 0 0 rg BT 246.85 176.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 292.97 176.10 Td (prospectively ) Tj ET Q q 0 0 0 rg BT 349.10 176.10 Td (as ) Tj ET Q q 0 0 0 rg BT 359.69 176.10 Td (a ) Tj ET Q q 0 0 0 rg BT 366.38 176.10 Td (reduction ) Tj ET Q q 0 0 0 rg BT 406.40 176.10 Td (of ) Tj ET Q q 0 0 0 rg BT 416.99 176.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 431.46 176.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 465.93 176.10 Td (rather ) Tj ET Q q 0 0 0 rg BT 491.50 176.10 Td (than ) Tj ET Q q 0 0 0 rg BT 510.98 176.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 539.88 176.10 Td (in ) Tj ET Q q 0 0 0 rg BT 549.92 176.10 Td (excess ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 164.10 Td (of ) Tj ET Q q 0 0 0 rg BT 46.67 164.10 Td (par ) Tj ET Q q 0 0 0 rg BT 61.77 164.10 Td (value ) Tj ET Q q 0 0 0 rg BT 85.77 164.10 Td (of ) Tj ET Q q 0 0 0 rg BT 96.44 164.10 Td (stock. ) Tj ET Q q 0 0 0 rg BT 122.21 164.10 Td (The ) Tj ET Q q 0 0 0 rg BT 140.10 164.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 154.65 164.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 184.75 164.10 Td (realized ) Tj ET Q q 0 0 0 rg BT 218.73 164.10 Td (as ) Tj ET Q q 0 0 0 rg BT 229.40 164.10 Td (a ) Tj ET Q q 0 0 0 rg BT 236.18 164.10 Td (result ) Tj ET Q q 0 0 0 rg BT 260.73 164.10 Td (of ) Tj ET Q q 0 0 0 rg BT 271.40 164.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 294.85 164.10 Td (related ) Tj ET Q q 0 0 0 rg BT 324.39 164.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 382.27 164.10 Td (credited ) Tj ET Q q 0 0 0 rg BT 416.81 164.10 Td (to ) Tj ET Q q 0 0 0 rg BT 426.92 164.10 Td (capital ) Tj ET Q q 0 0 0 rg BT 455.91 164.10 Td (in ) Tj ET Q q 0 0 0 rg BT 466.03 164.10 Td (excess ) Tj ET Q q 0 0 0 rg BT 494.46 164.10 Td (of ) Tj ET Q q 0 0 0 rg BT 505.13 164.10 Td (par ) Tj ET Q q 0 0 0 rg BT 520.24 164.10 Td (value ) Tj ET Q q 0 0 0 rg BT 544.23 164.10 Td (of ) Tj ET Q q 0 0 0 rg BT 554.90 164.10 Td (stock ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 152.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.22 152.10 Td ($92 ) Tj ET Q q 0 0 0 rg BT 71.89 152.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.78 152.10 Td ( ) Tj ET Q q 0 0 0 rg BT 103.45 152.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 113.89 152.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 133.89 152.10 Td ( ) Tj ET Q q 0 0 0 rg BT 136.56 152.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 153.67 152.10 Td ($147 ) Tj ET Q q 0 0 0 rg BT 176.33 152.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.22 152.10 Td ( ) Tj ET Q q 0 0 0 rg BT 207.89 152.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 218.34 152.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 238.34 152.10 Td (. ) Tj ET Q q 0 0 0 rg BT 243.31 152.10 Td (The ) Tj ET Q q 0 0 0 rg BT 261.53 152.10 Td (adoption ) Tj ET Q q 0 0 0 rg BT 299.19 152.10 Td (of ) Tj ET Q q 0 0 0 rg BT 310.19 152.10 Td (amended ) Tj ET Q q 0 0 0 rg BT 348.95 152.10 Td (guidance ) Tj ET Q q 0 0 0 rg BT 387.71 152.10 Td (for ) Tj ET Q q 0 0 0 rg BT 402.04 152.10 Td (both ) Tj ET Q q 0 0 0 rg BT 422.48 152.10 Td (items ) Tj ET Q q 0 0 0 rg BT 446.81 152.10 Td (reduced ) Tj ET Q q 0 0 0 rg BT 481.13 152.10 Td (the ) Tj ET Q q 0 0 0 rg BT 496.01 152.10 Td (ef) Tj ET Q q 0 0 0 rg BT 503.60 152.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 533.47 152.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 548.35 152.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 566.01 152.10 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 140.10 Td (2.4%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 56.83 140.10 Td ( ) Tj ET Q q 0 0 0 rg BT 59.57 140.10 Td (in ) Tj ET Q q 0 0 0 rg BT 70.09 140.10 Td (the ) Tj ET Q q 0 0 0 rg BT 85.05 140.10 Td (year ) Tj ET Q q 0 0 0 rg BT 105.00 140.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 131.61 140.10 Td (December ) Tj ET Q q 0 0 0 rg BT 175.44 140.10 Td (31, ) Tj ET Q q 0 0 0 rg BT 190.68 140.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 215.92 140.10 Td (Refer ) Tj ET Q q 0 0 0 rg BT 240.87 140.10 Td (to ) Tj ET Q q 0 0 0 rg BT 251.39 140.10 Td ("—Note ) Tj ET Q q 0 0 0 rg BT 287.65 140.10 Td (1. ) Tj ET Q q 0 0 0 rg BT 297.89 140.10 Td (Basis ) Tj ET Q q 0 0 0 rg BT 322.30 140.10 Td (of ) Tj ET Q q 0 0 0 rg BT 333.37 140.10 Td (Presentation ) Tj ET Q q 0 0 0 rg BT 385.54 140.10 Td (and ) Tj ET Q q 0 0 0 rg BT 402.72 140.10 Td (Recently ) Tj ET Q q 0 0 0 rg BT 441.01 140.10 Td (Issued ) Tj ET Q q 0 0 0 rg BT 468.69 140.10 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 518.09 140.10 Td (Standards" ) Tj ET Q q 0 0 0 rg BT 564.35 140.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 128.10 Td (more ) Tj ET Q q 0 0 0 rg BT 59.05 128.10 Td (information.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 104.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.58 104.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 75.39 104.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 108.41 104.10 Td (net ) Tj ET Q q 0 0 0 rg BT 123.66 104.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 164.46 104.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 183.05 104.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 242.16 104.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.62 104.10 Td ($317 ) Tj ET Q q 0 0 0 rg BT 287.66 104.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 316.55 104.10 Td ( ) Tj ET Q q 0 0 0 rg BT 319.58 104.10 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 329.83 104.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 388.94 104.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.94 104.10 Td (. ) Tj ET Q q 0 0 0 rg BT 414.26 104.10 Td (These ) Tj ET Q q 0 0 0 rg BT 441.17 104.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 500.28 104.10 Td (were ) Tj ET Q q 0 0 0 rg BT 522.74 104.10 Td (acquired ) Tj ET Q q 0 0 0 rg BT 560.19 104.10 Td (as ) Tj ET Q q 0 0 0 rg BT 571.56 104.10 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 92.10 Td (result ) Tj ET Q q 0 0 0 rg BT 61.78 92.10 Td (of ) Tj ET Q q 0 0 0 rg BT 73.67 92.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 104.43 92.10 Td (acquisitions ) Tj ET Q q 0 0 0 rg BT 155.76 92.10 Td (and ) Tj ET Q q 0 0 0 rg BT 173.76 92.10 Td (are ) Tj ET Q q 0 0 0 rg BT 189.53 92.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 221.41 92.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.75 92.10 Td (limitations ) Tj ET Q q 0 0 0 rg BT 279.09 92.10 Td (under ) Tj ET Q q 0 0 0 rg BT 305.41 92.10 Td (Section 382 ) Tj ET Q q 0 0 0 rg BT 356.47 92.10 Td (of ) Tj ET Q q 0 0 0 rg BT 368.36 92.10 Td (the ) Tj ET Q q 0 0 0 rg BT 384.13 92.10 Td (Internal ) Tj ET Q q 0 0 0 rg BT 418.79 92.10 Td (Revenue ) Tj ET Q q 0 0 0 rg BT 457.33 92.10 Td (Code. ) Tj ET Q q 0 0 0 rg BT 484.24 92.10 Td (The ) Tj ET Q q 0 0 0 rg BT 503.35 92.10 Td (net ) Tj ET Q q 0 0 0 rg BT 519.13 92.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 560.45 92.10 Td (loss ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 80.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 95.11 80.10 Td (expire ) Tj ET Q q 0 0 0 rg BT 123.13 80.10 Td (in ) Tj ET Q q 0 0 0 rg BT 133.94 80.10 Td (varying ) Tj ET Q q 0 0 0 rg BT 167.51 80.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 204.43 80.10 Td (beginning ) Tj ET Q q 0 0 0 rg BT 247.46 80.10 Td (in ) Tj ET Q q 0 0 0 rg BT 258.27 80.10 Td (2022. ) Tj ET Q q 0 0 0 rg BT 283.58 80.10 Td (The ) Tj ET Q q 0 0 0 rg BT 302.16 80.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 334.07 80.10 Td (and ) Tj ET Q q 0 0 0 rg BT 351.54 80.10 Td (state ) Tj ET Q q 0 0 0 rg BT 372.89 80.10 Td (net ) Tj ET Q q 0 0 0 rg BT 388.14 80.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 428.94 80.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 447.53 80.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 506.64 80.10 Td (expire ) Tj ET Q q 0 0 0 rg BT 534.66 80.10 Td (in ) Tj ET Q q 0 0 0 rg BT 545.47 80.10 Td (varying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 68.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 72.39 68.10 Td (beginning ) Tj ET Q q 0 0 0 rg BT 114.88 68.10 Td (in ) Tj ET Q q 0 0 0 rg BT 125.16 68.10 Td (2018 ) Tj ET Q q 0 0 0 rg BT 147.66 68.10 Td (\(certain ) Tj ET Q q 0 0 0 rg BT 180.69 68.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 217.08 68.10 Td (have ) Tj ET Q q 0 0 0 rg BT 238.46 68.10 Td (unlimited ) Tj ET Q q 0 0 0 rg BT 279.29 68.10 Td (lives\). ) Tj ET Q endstream endobj 167 0 obj <> endobj 168 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (At ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 48.89 749.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 107.87 749.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 127.87 749.10 Td (, ) Tj ET Q q 0 0 0 rg BT 133.26 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 140.59 749.10 Td (valuation ) Tj ET Q q 0 0 0 rg BT 180.69 749.10 Td (allowance ) Tj ET Q q 0 0 0 rg BT 224.12 749.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 235.34 749.10 Td ($2,827 ) Tj ET Q q 0 0 0 rg BT 265.73 749.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 294.63 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 297.52 749.10 Td (was ) Tj ET Q q 0 0 0 rg BT 315.96 749.10 Td (established ) Tj ET Q q 0 0 0 rg BT 363.29 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 377.84 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 392.95 749.10 Td (following ) Tj ET Q q 0 0 0 rg BT 434.73 749.10 Td (items: ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.06 749.10 Td ($2,654 ) Tj ET Q q 0 0 0 rg BT 492.45 749.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.35 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 524.24 749.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 564.34 749.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 67.87 737.10 Td (net ) Tj ET Q q 0 0 0 rg BT 83.08 737.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 123.84 737.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 142.40 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 159.83 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 175.04 737.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 200.80 737.10 Td (carryforwards, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.37 737.10 Td ($129 ) Tj ET Q q 0 0 0 rg BT 285.37 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.26 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 317.25 737.10 Td (for ) Tj ET Q q 0 0 0 rg BT 331.91 737.10 Td (state ) Tj ET Q q 0 0 0 rg BT 353.23 737.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 389.53 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 404.74 737.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 431.07 737.10 Td (including ) Tj ET Q q 0 0 0 rg BT 471.83 737.10 Td (net ) Tj ET Q q 0 0 0 rg BT 487.05 737.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 527.80 737.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 546.36 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 563.79 737.10 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 61.39 725.10 Td (carryforwards, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 122.59 725.10 Td ($10 ) Tj ET Q q 0 0 0 rg BT 140.22 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 169.11 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 171.74 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 186.02 725.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 206.43 725.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 239.04 725.10 Td (net ) Tj ET Q q 0 0 0 rg BT 253.89 725.10 Td (operating ) Tj ET Q q 0 0 0 rg BT 294.28 725.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 312.46 725.10 Td (carryforwards ) Tj ET Q q 0 0 0 rg BT 371.17 725.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 388.23 725.10 Td ($34 ) Tj ET Q q 0 0 0 rg BT 405.86 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.75 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 437.38 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 451.66 725.10 Td (other ) Tj ET Q q 0 0 0 rg BT 474.84 725.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 495.25 725.10 Td (Federal ) Tj ET Q q 0 0 0 rg BT 527.86 725.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 563.79 725.10 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (assets.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (Changes in the valuation allowance were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 652.60 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 652.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 652.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 652.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 652.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 652.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 652.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 626.60 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 626.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 626.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 626.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 626.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 626.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 626.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 600.60 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 600.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 600.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 600.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 600.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 600.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 600.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 574.60 316.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 352.50 574.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 574.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 574.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 574.60 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 574.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 574.60 71.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 665.6 m 426.5 665.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 426.5 665.6 m 430.5 665.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 665.6 m 501.5 665.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 501.5 665.6 m 505.5 665.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 665.6 m 576.5 665.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 652.6 m 426.5 652.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 652.6 m 501.5 652.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 652.6 m 576.5 652.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 574.6 m 426.5 574.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 562.6 m 426.5 562.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 356.5 560.6 m 426.5 560.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 574.6 m 501.5 574.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 562.6 m 501.5 562.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 560.6 m 501.5 560.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 574.6 m 576.5 574.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 562.6 m 576.5 562.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 560.6 m 576.5 560.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 669.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 421.70 669.83 Td (Y) Tj ET Q q 0 0 0 rg BT 427.03 669.83 Td (ear) Tj ET Q q 0 0 0 rg BT 437.62 669.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 498.35 669.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 656.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 383.00 656.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 457.50 656.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 656.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 643.17 Td (Balance at beginning of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.00 643.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 643.17 Td (3,078) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 643.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 643.17 Td (3,534) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 643.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 643.17 Td (4,259) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 630.17 Td (Provision) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 630.17 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 630.17 Td (39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 630.17 Td (71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 617.17 Td (Utilization) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.30 617.22 Td (\(335) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.65 617.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 617.22 Td (\(355) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 617.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 617.17 Td (\(436) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 617.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 604.17 Td (Foreign currency translation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 604.17 Td (341) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.30 604.22 Td (\(142) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 604.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 604.17 Td (\(366) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 604.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 591.17 Td (Acquisitions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.65 591.17 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 492.65 591.17 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 591.17 Td (6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 578.17 Td (Non U.S. rate change) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.30 578.22 Td (\(309) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.65 578.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 578.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 578.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 565.17 Td (Balance at end of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.00 565.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 565.17 Td (2,827) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 565.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 565.17 Td (3,078) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 565.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 565.17 Td (3,534) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 540.50 Td (Income ) Tj ET Q q 0 0 0 rg BT 68.49 540.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 83.20 540.50 Td (payments ) Tj ET Q q 0 0 0 rg BT 124.03 540.50 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 145.96 540.50 Td ($546 ) Tj ET Q q 0 0 0 rg BT 168.46 540.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 197.35 540.50 Td ( ) Tj ET Q q 0 0 0 rg BT 199.85 540.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 210.13 540.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 230.13 540.50 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 235.13 540.50 Td ($2.0 ) Tj ET Q q 0 0 0 rg BT 255.13 540.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 281.24 540.50 Td ( ) Tj ET Q q 0 0 0 rg BT 283.74 540.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 294.02 540.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.02 540.50 Td ( ) Tj ET Q q 0 0 0 rg BT 316.52 540.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.46 540.50 Td ($577 ) Tj ET Q q 0 0 0 rg BT 355.96 540.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.85 540.50 Td ( ) Tj ET Q q 0 0 0 rg BT 387.35 540.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.63 540.50 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.63 540.50 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 516.50 Td (Business ) Tj ET Q q 0 0 0 rg BT 73.94 516.50 Td (is ) Tj ET Q q 0 0 0 rg BT 82.99 516.50 Td (conducted ) Tj ET Q q 0 0 0 rg BT 126.46 516.50 Td (in ) Tj ET Q q 0 0 0 rg BT 136.62 516.50 Td (various ) Tj ET Q q 0 0 0 rg BT 168.43 516.50 Td (countries ) Tj ET Q q 0 0 0 rg BT 207.46 516.50 Td (throughout ) Tj ET Q q 0 0 0 rg BT 253.73 516.50 Td (the ) Tj ET Q q 0 0 0 rg BT 268.32 516.50 Td (world ) Tj ET Q q 0 0 0 rg BT 294.03 516.50 Td (and ) Tj ET Q q 0 0 0 rg BT 310.85 516.50 Td (is ) Tj ET Q q 0 0 0 rg BT 319.90 516.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 350.60 516.50 Td (to ) Tj ET Q q 0 0 0 rg BT 360.76 516.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 375.35 516.50 Td (in ) Tj ET Q q 0 0 0 rg BT 385.51 516.50 Td (numerous ) Tj ET Q q 0 0 0 rg BT 427.32 516.50 Td (jurisdictions. ) Tj ET Q q 0 0 0 rg BT 481.12 516.50 Td (A) Tj ET Q q 0 0 0 rg BT 487.79 516.50 Td ( ) Tj ET Q q 0 0 0 rg BT 490.17 516.50 Td (significant ) Tj ET Q q 0 0 0 rg BT 534.76 516.50 Td (number ) Tj ET Q q 0 0 0 rg BT 567.68 516.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 504.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.03 504.50 Td (returns ) Tj ET Q q 0 0 0 rg BT 79.60 504.50 Td (that ) Tj ET Q q 0 0 0 rg BT 96.41 504.50 Td (are ) Tj ET Q q 0 0 0 rg BT 110.42 504.50 Td (filed ) Tj ET Q q 0 0 0 rg BT 130.56 504.50 Td (are ) Tj ET Q q 0 0 0 rg BT 144.57 504.50 Td (subject ) Tj ET Q q 0 0 0 rg BT 174.71 504.50 Td (to ) Tj ET Q q 0 0 0 rg BT 184.30 504.50 Td (examination ) Tj ET Q q 0 0 0 rg BT 235.53 504.50 Td (by ) Tj ET Q q 0 0 0 rg BT 247.34 504.50 Td (various ) Tj ET Q q 0 0 0 rg BT 278.59 504.50 Td (Federal, ) Tj ET Q q 0 0 0 rg BT 312.88 504.50 Td (state ) Tj ET Q q 0 0 0 rg BT 333.02 504.50 Td (and ) Tj ET Q q 0 0 0 rg BT 349.27 504.50 Td (local ) Tj ET Q q 0 0 0 rg BT 370.51 504.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 384.54 504.50 Td (authorities. ) Tj ET Q q 0 0 0 rg BT 430.93 504.50 Td (T) Tj ET Q q 0 0 0 rg BT 436.34 504.50 Td (ax ) Tj ET Q q 0 0 0 rg BT 447.58 504.50 Td (examinations ) Tj ET Q q 0 0 0 rg BT 502.71 504.50 Td (are ) Tj ET Q q 0 0 0 rg BT 516.73 504.50 Td (often ) Tj ET Q q 0 0 0 rg BT 539.08 504.50 Td (complex, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 492.50 Td (as ) Tj ET Q q 0 0 0 rg BT 47.57 492.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 63.03 492.50 Td (authorities ) Tj ET Q q 0 0 0 rg BT 108.48 492.50 Td (may ) Tj ET Q q 0 0 0 rg BT 128.94 492.50 Td (disagree ) Tj ET Q q 0 0 0 rg BT 165.50 492.50 Td (with ) Tj ET Q q 0 0 0 rg BT 186.52 492.50 Td (the ) Tj ET Q q 0 0 0 rg BT 201.97 492.50 Td (treatment ) Tj ET Q q 0 0 0 rg BT 242.97 492.50 Td (of ) Tj ET Q q 0 0 0 rg BT 254.55 492.50 Td (items ) Tj ET Q q 0 0 0 rg BT 279.45 492.50 Td (reported ) Tj ET Q q 0 0 0 rg BT 316.01 492.50 Td (requiring ) Tj ET Q q 0 0 0 rg BT 355.91 492.50 Td (several ) Tj ET Q q 0 0 0 rg BT 387.46 492.50 Td (years ) Tj ET Q q 0 0 0 rg BT 411.80 492.50 Td (to ) Tj ET Q q 0 0 0 rg BT 422.82 492.50 Td (resolve. ) Tj ET Q q 0 0 0 rg BT 457.44 492.50 Td (Liabilities ) Tj ET Q q 0 0 0 rg BT 501.23 492.50 Td (are ) Tj ET Q q 0 0 0 rg BT 516.68 492.50 Td (established ) Tj ET Q q 0 0 0 rg BT 564.35 492.50 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 480.50 Td (possible ) Tj ET Q q 0 0 0 rg BT 71.73 480.50 Td (assessments ) Tj ET Q q 0 0 0 rg BT 123.01 480.50 Td (by ) Tj ET Q q 0 0 0 rg BT 135.97 480.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 151.14 480.50 Td (authorities ) Tj ET Q q 0 0 0 rg BT 196.30 480.50 Td (resulting ) Tj ET Q q 0 0 0 rg BT 234.25 480.50 Td (from ) Tj ET Q q 0 0 0 rg BT 256.64 480.50 Td (known ) Tj ET Q q 0 0 0 rg BT 286.82 480.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 301.99 480.50 Td (exposures ) Tj ET Q q 0 0 0 rg BT 344.93 480.50 Td (including, ) Tj ET Q q 0 0 0 rg BT 388.16 480.50 Td (but ) Tj ET Q q 0 0 0 rg BT 403.89 480.50 Td (not ) Tj ET Q q 0 0 0 rg BT 419.62 480.50 Td (limited ) Tj ET Q q 0 0 0 rg BT 450.90 480.50 Td (to, ) Tj ET Q q 0 0 0 rg BT 464.13 480.50 Td (transfer ) Tj ET Q q 0 0 0 rg BT 497.63 480.50 Td (pricing ) Tj ET Q q 0 0 0 rg BT 528.90 480.50 Td (matters, ) Tj ET Q q 0 0 0 rg BT 563.79 480.50 Td (tax ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 468.50 Td (credit ) Tj ET Q q 0 0 0 rg BT 60.96 468.50 Td (deductibility ) Tj ET Q q 0 0 0 rg BT 113.71 468.50 Td (of ) Tj ET Q q 0 0 0 rg BT 124.24 468.50 Td (certain ) Tj ET Q q 0 0 0 rg BT 153.65 468.50 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 194.45 468.50 Td (and ) Tj ET Q q 0 0 0 rg BT 211.09 468.50 Td (deemed ) Tj ET Q q 0 0 0 rg BT 244.38 468.50 Td (repatriation ) Tj ET Q q 0 0 0 rg BT 292.67 468.50 Td (transition ) Tj ET Q q 0 0 0 rg BT 332.65 468.50 Td (tax. ) Tj ET Q q 0 0 0 rg BT 349.56 468.50 Td (Such ) Tj ET Q q 0 0 0 rg BT 371.77 468.50 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 411.18 468.50 Td (represent ) Tj ET Q q 0 0 0 rg BT 450.03 468.50 Td (a ) Tj ET Q q 0 0 0 rg BT 456.67 468.50 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 501.63 468.50 Td (provision ) Tj ET Q q 0 0 0 rg BT 541.60 468.50 Td (for ) Tj ET Q q 0 0 0 rg BT 555.47 468.50 Td (taxes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 456.50 Td (ultimately ) Tj ET Q q 0 0 0 rg BT 79.54 456.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 118.07 456.50 Td (to ) Tj ET Q q 0 0 0 rg BT 128.84 456.50 Td (be ) Tj ET Q q 0 0 0 rg BT 141.27 456.50 Td (paid ) Tj ET Q q 0 0 0 rg BT 161.48 456.50 Td (and ) Tj ET Q q 0 0 0 rg BT 178.91 456.50 Td (may ) Tj ET Q q 0 0 0 rg BT 199.12 456.50 Td (need ) Tj ET Q q 0 0 0 rg BT 220.99 456.50 Td (to ) Tj ET Q q 0 0 0 rg BT 231.76 456.50 Td (be ) Tj ET Q q 0 0 0 rg BT 244.19 456.50 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 280.51 456.50 Td (over ) Tj ET Q q 0 0 0 rg BT 301.27 456.50 Td (time ) Tj ET Q q 0 0 0 rg BT 322.04 456.50 Td (as ) Tj ET Q q 0 0 0 rg BT 333.36 456.50 Td (more ) Tj ET Q q 0 0 0 rg BT 356.90 456.50 Td (information ) Tj ET Q q 0 0 0 rg BT 407.11 456.50 Td (becomes ) Tj ET Q q 0 0 0 rg BT 445.09 456.50 Td (known. ) Tj ET Q q 0 0 0 rg BT 477.59 456.50 Td (The ) Tj ET Q q 0 0 0 rg BT 496.13 456.50 Td (ef) Tj ET Q q 0 0 0 rg BT 503.71 456.50 Td (fect ) Tj ET Q q 0 0 0 rg BT 521.69 456.50 Td (of ) Tj ET Q q 0 0 0 rg BT 533.02 456.50 Td (changes ) Tj ET Q q 0 0 0 rg BT 568.22 456.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 444.50 Td (estimates ) Tj ET Q q 0 0 0 rg BT 75.71 444.50 Td (related ) Tj ET Q q 0 0 0 rg BT 105.41 444.50 Td (to ) Tj ET Q q 0 0 0 rg BT 115.69 444.50 Td (contingent ) Tj ET Q q 0 0 0 rg BT 160.40 444.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 175.12 444.50 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 214.84 444.50 Td (is ) Tj ET Q q 0 0 0 rg BT 224.01 444.50 Td (included ) Tj ET Q q 0 0 0 rg BT 260.94 444.50 Td (in ) Tj ET Q q 0 0 0 rg BT 271.22 444.50 Td (the ) Tj ET Q q 0 0 0 rg BT 285.94 444.50 Td (ef) Tj ET Q q 0 0 0 rg BT 293.52 444.50 Td (fective ) Tj ET Q q 0 0 0 rg BT 323.23 444.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 337.94 444.50 Td (rate ) Tj ET Q q 0 0 0 rg BT 355.43 444.50 Td (reconciliation ) Tj ET Q q 0 0 0 rg BT 412.90 444.50 Td (above.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 422.90 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 422.90 Td ( reconciliation of the beginning and ending amount of gross unrecognized tax benefits is as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 386.40 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 386.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 386.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 386.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 386.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 386.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 386.40 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 360.40 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 360.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 360.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 360.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 360.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 360.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 360.40 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 334.40 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 334.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 334.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 334.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 334.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 334.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 334.40 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 308.40 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 308.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 308.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 308.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 308.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 308.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 308.40 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 282.40 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 282.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 282.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 282.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 282.40 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 282.40 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 282.40 70.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 399.4 m 429.5 399.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 429.5 399.4 m 433.5 399.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 399.4 m 502.5 399.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 502.5 399.4 m 506.5 399.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 399.4 m 576.5 399.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 386.4 m 429.5 386.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 386.4 m 502.5 386.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 386.4 m 576.5 386.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 282.4 m 429.5 282.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 282.4 m 502.5 282.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 282.4 m 576.5 282.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 270.4 m 429.5 270.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 268.4 m 429.5 268.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 270.4 m 502.5 270.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 268.4 m 502.5 268.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 270.4 m 576.5 270.4 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 268.4 m 576.5 268.4 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 403.65 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 423.70 403.63 Td (Y) Tj ET Q q 0 0 0 rg BT 429.03 403.63 Td (ear) Tj ET Q q 0 0 0 rg BT 439.62 403.63 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 500.35 403.63 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 390.65 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 386.50 390.63 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 459.50 390.63 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.00 390.63 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 376.97 Td (Balance at beginning of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 376.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 376.97 Td (995) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 376.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 376.97 Td (944) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 376.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 376.97 Td (934) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 363.97 Td (Gross additions to tax positions related to current year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 363.97 Td (173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 363.97 Td (49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 363.97 Td (52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 350.97 Td (Gross additions to tax positions related to prior years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 350.97 Td (30) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 350.97 Td (49) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 350.97 Td (56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 337.97 Td (Gross additions to tax positions assumed in acquisitions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 337.97 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 337.97 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 337.97 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 324.97 Td (Gross reductions to tax positions related to prior years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 325.02 Td (\(22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 324.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.30 325.02 Td (\(22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 324.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 324.97 Td (\(34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 324.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 311.97 Td (Settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 312.02 Td (\(20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 311.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.30 312.02 Td (\(13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 311.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 311.97 Td (\(46) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 311.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 298.97 Td (Reductions to tax positions related to lapse of statute) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.30 299.02 Td (\(13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 298.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.30 299.02 Td (\(4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 298.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 298.97 Td (\(9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 298.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 285.97 Td (Cumulative translation adjustment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 285.97 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 490.30 286.02 Td (\(9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 285.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 285.97 Td (\(10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 285.97 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 272.97 Td (Balance at end of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 272.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 272.97 Td (1,155) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 272.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 272.97 Td (995) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 272.97 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 272.97 Td (944) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 248.30 Td (Additional information regarding unrecognized tax benefits is as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 213.80 348.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 213.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 213.80 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 213.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 213.80 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 213.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 213.80 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 185.80 348.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 384.50 185.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 388.50 185.80 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 448.50 185.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 452.50 185.80 60.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 512.50 185.80 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 185.80 60.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 225.79999999999995 m 448.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 225.79999999999995 m 452.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 225.79999999999995 m 512.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 225.79999999999995 m 516.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 225.79999999999995 m 576.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 225.79999999999995 m 448.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 388.5 213.79999999999995 m 448.5 213.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 448.5 225.79999999999995 m 452.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 225.79999999999995 m 512.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 452.5 213.79999999999995 m 512.5 213.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 512.5 225.79999999999995 m 516.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 225.79999999999995 m 576.5 225.79999999999995 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 516.5 213.79999999999995 m 576.5 213.79999999999995 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 229.75 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 437.70 229.88 Td (Y) Tj ET Q q 0 0 0 rg BT 443.03 229.88 Td (ear) Tj ET Q q 0 0 0 rg BT 453.62 229.88 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 514.35 229.88 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 217.75 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 410.00 217.88 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.00 217.88 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.00 217.88 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 204.37 Td (Unrecognized tax benefits that if recognized would impact the ef) Tj ET Q q 0 0 0 rg BT 298.53 204.37 Td (fective tax rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 391.00 204.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.15 204.37 Td (1,002) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.00 204.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 204.37 Td (854) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.00 204.37 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 204.37 Td (671) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 190.37 Td (Accrued interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 429.65 190.37 Td (148) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 190.37 Td (1) Tj ET Q q 0 0 0 rg BT 498.65 190.37 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 190.37 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 176.37 Td (Accrued penalties) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.65 176.37 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 176.37 Td (17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 176.37 Td (16) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 150.70 Td (Accrued ) Tj ET Q q 0 0 0 rg BT 72.21 150.70 Td (interest ) Tj ET Q q 0 0 0 rg BT 103.99 150.70 Td (and ) Tj ET Q q 0 0 0 rg BT 120.77 150.70 Td (penalties ) Tj ET Q q 0 0 0 rg BT 158.66 150.70 Td (payable ) Tj ET Q q 0 0 0 rg BT 192.09 150.70 Td (for ) Tj ET Q q 0 0 0 rg BT 206.10 150.70 Td (unrecognized ) Tj ET Q q 0 0 0 rg BT 262.30 150.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 276.86 150.70 Td (benefits ) Tj ET Q q 0 0 0 rg BT 310.86 150.70 Td (are ) Tj ET Q q 0 0 0 rg BT 325.41 150.70 Td (included ) Tj ET Q q 0 0 0 rg BT 362.19 150.70 Td (in ) Tj ET Q q 0 0 0 rg BT 372.31 150.70 Td (either ) Tj ET Q q 0 0 0 rg BT 397.42 150.70 Td (current ) Tj ET Q q 0 0 0 rg BT 428.08 150.70 Td (or ) Tj ET Q q 0 0 0 rg BT 438.75 150.70 Td (non-current ) Tj ET Q q 0 0 0 rg BT 487.74 150.70 Td (income ) Tj ET Q q 0 0 0 rg BT 519.52 150.70 Td (taxes ) Tj ET Q q 0 0 0 rg BT 542.41 150.70 Td (payable. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 138.70 Td (Interest ) Tj ET Q q 0 0 0 rg BT 68.49 138.70 Td (and ) Tj ET Q q 0 0 0 rg BT 85.42 138.70 Td (penalties ) Tj ET Q q 0 0 0 rg BT 123.47 138.70 Td (related ) Tj ET Q q 0 0 0 rg BT 153.17 138.70 Td (to ) Tj ET Q q 0 0 0 rg BT 163.45 138.70 Td (unrecognized ) Tj ET Q q 0 0 0 rg BT 219.81 138.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 234.53 138.70 Td (benefits ) Tj ET Q q 0 0 0 rg BT 268.68 138.70 Td (are ) Tj ET Q q 0 0 0 rg BT 283.39 138.70 Td (included ) Tj ET Q q 0 0 0 rg BT 320.32 138.70 Td (in ) Tj ET Q q 0 0 0 rg BT 330.60 138.70 Td (income ) Tj ET Q q 0 0 0 rg BT 362.53 138.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 377.25 138.70 Td (expense. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 114.70 Td (BMS ) Tj ET Q q 0 0 0 rg BT 58.62 114.70 Td (is ) Tj ET Q q 0 0 0 rg BT 66.79 114.70 Td (currently ) Tj ET Q q 0 0 0 rg BT 104.38 114.70 Td (under ) Tj ET Q q 0 0 0 rg BT 128.65 114.70 Td (examination ) Tj ET Q q 0 0 0 rg BT 179.58 114.70 Td (by ) Tj ET Q q 0 0 0 rg BT 191.08 114.70 Td (a ) Tj ET Q q 0 0 0 rg BT 197.02 114.70 Td (number ) Tj ET Q q 0 0 0 rg BT 229.06 114.70 Td (of ) Tj ET Q q 0 0 0 rg BT 238.89 114.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 252.61 114.70 Td (authorities ) Tj ET Q q 0 0 0 rg BT 296.32 114.70 Td (which ) Tj ET Q q 0 0 0 rg BT 322.25 114.70 Td (have ) Tj ET Q q 0 0 0 rg BT 342.63 114.70 Td (proposed ) Tj ET Q q 0 0 0 rg BT 380.79 114.70 Td (or ) Tj ET Q q 0 0 0 rg BT 390.62 114.70 Td (are ) Tj ET Q q 0 0 0 rg BT 404.33 114.70 Td (considering ) Tj ET Q q 0 0 0 rg BT 452.48 114.70 Td (proposing ) Tj ET Q q 0 0 0 rg BT 493.98 114.70 Td (material ) Tj ET Q q 0 0 0 rg BT 528.24 114.70 Td (adjustments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 102.70 Td (to ) Tj ET Q q 0 0 0 rg BT 46.35 102.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 61.14 102.70 Td (positions ) Tj ET Q q 0 0 0 rg BT 99.83 102.70 Td (for ) Tj ET Q q 0 0 0 rg BT 114.07 102.70 Td (issues ) Tj ET Q q 0 0 0 rg BT 140.53 102.70 Td (such ) Tj ET Q q 0 0 0 rg BT 161.43 102.70 Td (as ) Tj ET Q q 0 0 0 rg BT 172.34 102.70 Td (transfer ) Tj ET Q q 0 0 0 rg BT 205.45 102.70 Td (pricing, ) Tj ET Q q 0 0 0 rg BT 238.85 102.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 268.62 102.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 283.41 102.70 Td (credits ) Tj ET Q q 0 0 0 rg BT 312.64 102.70 Td (and ) Tj ET Q q 0 0 0 rg BT 329.65 102.70 Td (the ) Tj ET Q q 0 0 0 rg BT 344.44 102.70 Td (deductibility ) Tj ET Q q 0 0 0 rg BT 397.56 102.70 Td (of ) Tj ET Q q 0 0 0 rg BT 408.47 102.70 Td (certain ) Tj ET Q q 0 0 0 rg BT 438.24 102.70 Td (expenses. ) Tj ET Q q 0 0 0 rg BT 479.41 102.70 Td (It ) Tj ET Q q 0 0 0 rg BT 488.09 102.70 Td (is ) Tj ET Q q 0 0 0 rg BT 497.34 102.70 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 543.23 102.70 Td (possible ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 90.70 Td (that ) Tj ET Q q 0 0 0 rg BT 53.31 90.70 Td (new ) Tj ET Q q 0 0 0 rg BT 72.28 90.70 Td (issues ) Tj ET Q q 0 0 0 rg BT 98.49 90.70 Td (will ) Tj ET Q q 0 0 0 rg BT 116.36 90.70 Td (be ) Tj ET Q q 0 0 0 rg BT 128.11 90.70 Td (raised ) Tj ET Q q 0 0 0 rg BT 154.31 90.70 Td (by ) Tj ET Q q 0 0 0 rg BT 166.62 90.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 181.15 90.70 Td (authorities ) Tj ET Q q 0 0 0 rg BT 225.68 90.70 Td (which ) Tj ET Q q 0 0 0 rg BT 252.43 90.70 Td (may ) Tj ET Q q 0 0 0 rg BT 271.96 90.70 Td (require ) Tj ET Q q 0 0 0 rg BT 302.59 90.70 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 352.68 90.70 Td (to ) Tj ET Q q 0 0 0 rg BT 362.77 90.70 Td (the ) Tj ET Q q 0 0 0 rg BT 377.30 90.70 Td (amount ) Tj ET Q q 0 0 0 rg BT 409.61 90.70 Td (of ) Tj ET Q q 0 0 0 rg BT 420.26 90.70 Td (unrecognized ) Tj ET Q q 0 0 0 rg BT 476.43 90.70 Td (tax ) Tj ET Q q 0 0 0 rg BT 490.97 90.70 Td (benefits; ) Tj ET Q q 0 0 0 rg BT 527.71 90.70 Td (however) Tj ET Q q 0 0 0 rg BT 561.74 90.70 Td (, ) Tj ET Q q 0 0 0 rg BT 566.56 90.70 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 78.70 Td (estimate ) Tj ET Q q 0 0 0 rg BT 71.82 78.70 Td (of ) Tj ET Q q 0 0 0 rg BT 82.65 78.70 Td (such ) Tj ET Q q 0 0 0 rg BT 103.48 78.70 Td (adjustments ) Tj ET Q q 0 0 0 rg BT 153.75 78.70 Td (cannot ) Tj ET Q q 0 0 0 rg BT 182.91 78.70 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 228.72 78.70 Td (be ) Tj ET Q q 0 0 0 rg BT 240.66 78.70 Td (made ) Tj ET Q q 0 0 0 rg BT 264.82 78.70 Td (at ) Tj ET Q q 0 0 0 rg BT 274.54 78.70 Td (this ) Tj ET Q q 0 0 0 rg BT 291.48 78.70 Td (time.) Tj ET Q endstream endobj 169 0 obj <> endobj 170 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (It ) Tj ET Q q 0 0 0 rg BT 45.13 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 54.83 749.10 Td (also ) Tj ET Q q 0 0 0 rg BT 73.96 749.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 120.30 749.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 156.10 749.10 Td (that ) Tj ET Q q 0 0 0 rg BT 174.13 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 189.37 749.10 Td (total ) Tj ET Q q 0 0 0 rg BT 210.17 749.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 243.19 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 254.54 749.10 Td (unrecognized ) Tj ET Q q 0 0 0 rg BT 311.43 749.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 326.67 749.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 361.35 749.10 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.59 749.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 430.70 749.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.70 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 453.72 749.10 Td (could ) Tj ET Q q 0 0 0 rg BT 478.97 749.10 Td (decrease ) Tj ET Q q 0 0 0 rg BT 516.41 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 527.21 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 542.45 749.10 Td (range ) Tj ET Q q 0 0 0 rg BT 567.68 749.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 96.02 737.10 Td ($255 ) Tj ET Q q 0 0 0 rg BT 118.29 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 147.18 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 149.44 737.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 159.49 737.10 Td ($315 ) Tj ET Q q 0 0 0 rg BT 181.75 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 210.64 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 212.91 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 222.95 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 237.43 737.10 Td (next ) Tj ET Q q 0 0 0 rg BT 256.91 737.10 Td (twelve ) Tj ET Q q 0 0 0 rg BT 285.83 737.10 Td (months ) Tj ET Q q 0 0 0 rg BT 317.55 737.10 Td (as ) Tj ET Q q 0 0 0 rg BT 328.14 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 334.84 737.10 Td (result ) Tj ET Q q 0 0 0 rg BT 359.33 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 369.92 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 384.40 737.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 427.77 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 438.36 737.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 467.83 737.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 482.31 737.10 Td (audits ) Tj ET Q q 0 0 0 rg BT 508.46 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 525.16 737.10 Td (other ) Tj ET Q q 0 0 0 rg BT 547.97 737.10 Td (events. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.53 725.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 93.04 725.10 Td (change ) Tj ET Q q 0 0 0 rg BT 124.33 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 135.09 725.10 Td (unrecognized ) Tj ET Q q 0 0 0 rg BT 191.93 725.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 207.12 725.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 241.76 725.10 Td (may ) Tj ET Q q 0 0 0 rg BT 261.95 725.10 Td (result ) Tj ET Q q 0 0 0 rg BT 287.15 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 297.90 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 313.10 725.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 350.51 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 361.82 725.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 404.79 725.10 Td (taxes, ) Tj ET Q q 0 0 0 rg BT 430.81 725.10 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 477.67 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 488.98 725.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 519.16 725.10 Td (deferred ) Tj ET Q q 0 0 0 rg BT 555.45 725.10 Td (taxes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (and/or ) Tj ET Q q 0 0 0 rg BT 63.34 713.10 Td (recognition ) Tj ET Q q 0 0 0 rg BT 110.68 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 120.80 713.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 134.81 713.10 Td (benefits. ) Tj ET Q q 0 0 0 rg BT 170.76 713.10 Td (It ) Tj ET Q q 0 0 0 rg BT 178.66 713.10 Td (is ) Tj ET Q q 0 0 0 rg BT 187.12 713.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 232.23 713.10 Td (possible ) Tj ET Q q 0 0 0 rg BT 266.80 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 283.59 713.10 Td (new ) Tj ET Q q 0 0 0 rg BT 302.05 713.10 Td (issues ) Tj ET Q q 0 0 0 rg BT 327.73 713.10 Td (will ) Tj ET Q q 0 0 0 rg BT 345.08 713.10 Td (be ) Tj ET Q q 0 0 0 rg BT 356.31 713.10 Td (raised ) Tj ET Q q 0 0 0 rg BT 381.98 713.10 Td (by ) Tj ET Q q 0 0 0 rg BT 393.78 713.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 407.79 713.10 Td (authorities ) Tj ET Q q 0 0 0 rg BT 451.79 713.10 Td (that ) Tj ET Q q 0 0 0 rg BT 468.58 713.10 Td (may ) Tj ET Q q 0 0 0 rg BT 487.59 713.10 Td (increase ) Tj ET Q q 0 0 0 rg BT 522.14 713.10 Td (unrecognized ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 50.18 701.10 Td (benefits; ) Tj ET Q q 0 0 0 rg BT 86.57 701.10 Td (however) Tj ET Q q 0 0 0 rg BT 120.60 701.10 Td (, ) Tj ET Q q 0 0 0 rg BT 125.06 701.10 Td (an ) Tj ET Q q 0 0 0 rg BT 136.46 701.10 Td (estimate ) Tj ET Q q 0 0 0 rg BT 171.73 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 182.02 701.10 Td (such ) Tj ET Q q 0 0 0 rg BT 202.31 701.10 Td (increases ) Tj ET Q q 0 0 0 rg BT 240.92 701.10 Td (cannot ) Tj ET Q q 0 0 0 rg BT 269.53 701.10 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 314.81 701.10 Td (be ) Tj ET Q q 0 0 0 rg BT 326.21 701.10 Td (made ) Tj ET Q q 0 0 0 rg BT 349.82 701.10 Td (at ) Tj ET Q q 0 0 0 rg BT 359.00 701.10 Td (this ) Tj ET Q q 0 0 0 rg BT 375.41 701.10 Td (time. ) Tj ET Q q 0 0 0 rg BT 397.64 701.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 420.72 701.10 Td (believes ) Tj ET Q q 0 0 0 rg BT 455.44 701.10 Td (that ) Tj ET Q q 0 0 0 rg BT 472.40 701.10 Td (it ) Tj ET Q q 0 0 0 rg BT 479.91 701.10 Td (has ) Tj ET Q q 0 0 0 rg BT 495.20 701.10 Td (adequately ) Tj ET Q q 0 0 0 rg BT 540.47 701.10 Td (provided ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.16 689.10 Td (all ) Tj ET Q q 0 0 0 rg BT 62.66 689.10 Td (open ) Tj ET Q q 0 0 0 rg BT 84.59 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 99.31 689.10 Td (years ) Tj ET Q q 0 0 0 rg BT 122.91 689.10 Td (by ) Tj ET Q q 0 0 0 rg BT 135.41 689.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 150.13 689.10 Td (jurisdiction.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.49 665.10 Td (following ) Tj ET Q q 0 0 0 rg BT 94.31 665.10 Td (is ) Tj ET Q q 0 0 0 rg BT 102.92 665.10 Td (a ) Tj ET Q q 0 0 0 rg BT 109.30 665.10 Td (summary ) Tj ET Q q 0 0 0 rg BT 148.45 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 158.72 665.10 Td (major ) Tj ET Q q 0 0 0 rg BT 183.98 665.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 198.14 665.10 Td (jurisdictions ) Tj ET Q q 0 0 0 rg BT 249.52 665.10 Td (for ) Tj ET Q q 0 0 0 rg BT 263.12 665.10 Td (which ) Tj ET Q q 0 0 0 rg BT 289.50 665.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 303.65 665.10 Td (authorities ) Tj ET Q q 0 0 0 rg BT 347.80 665.10 Td (may ) Tj ET Q q 0 0 0 rg BT 366.96 665.10 Td (assert ) Tj ET Q q 0 0 0 rg BT 391.66 665.10 Td (additional ) Tj ET Q q 0 0 0 rg BT 433.59 665.10 Td (taxes ) Tj ET Q q 0 0 0 rg BT 456.08 665.10 Td (based ) Tj ET Q q 0 0 0 rg BT 480.79 665.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 502.72 665.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 516.88 665.10 Td (years ) Tj ET Q q 0 0 0 rg BT 539.92 665.10 Td (currently ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (under ) Tj ET Q q 0 0 0 rg BT 61.27 653.10 Td (audit ) Tj ET Q q 0 0 0 rg BT 83.76 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 100.70 653.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 147.64 653.10 Td (years ) Tj ET Q q 0 0 0 rg BT 171.24 653.10 Td (that ) Tj ET Q q 0 0 0 rg BT 188.73 653.10 Td (will ) Tj ET Q q 0 0 0 rg BT 206.79 653.10 Td (likely ) Tj ET Q q 0 0 0 rg BT 232.06 653.10 Td (be ) Tj ET Q q 0 0 0 rg BT 244.00 653.10 Td (audited:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 642.60 470.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 642.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 642.60 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 616.60 470.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 616.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 616.60 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 590.60 470.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 590.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 510.50 590.60 66.00 -13.00 re f /GS0 gs BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 633.17 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.20 633.17 Td (2008 to 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 620.17 Td (Canada) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.20 620.17 Td (2006 to 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 607.17 Td (France) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.20 607.17 Td (2014 to 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 594.17 Td (Germany) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.20 594.17 Td (2007 to 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 581.17 Td (Italy) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.20 581.17 Td (2016 to 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 568.17 Td (Mexico) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.55 568.17 Td (201) Tj ET Q q 0 0 0 rg BT 535.18 568.17 Td (1 to 2017) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 539.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 539.10 Td (8) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 539.10 Td (. EARNINGS PER SHARE) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 502.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 502.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 502.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 502.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 502.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 476.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 476.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 476.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 476.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 476.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 450.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 450.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 450.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 450.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 450.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 424.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 424.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 424.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 424.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 424.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 424.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 424.60 69.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 515.6 m 430.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 515.6 m 434.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 515.6 m 503.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 503.5 515.6 m 507.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 515.6 m 576.5 515.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 502.6 m 430.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 502.6 m 503.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 502.6 m 576.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 489.6 m 430.5 489.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 502.6 m 503.5 502.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 489.6 m 503.5 489.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 489.6 m 576.5 489.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 450.6 m 430.5 450.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 450.6 m 503.5 450.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 450.6 m 576.5 450.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 438.6 m 430.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 436.6 m 430.5 436.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 438.6 m 503.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 436.6 m 503.5 436.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 438.6 m 576.5 438.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 436.6 m 576.5 436.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 519.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 424.20 519.83 Td (Y) Tj ET Q q 0 0 0 rg BT 429.53 519.83 Td (ear) Tj ET Q q 0 0 0 rg BT 440.12 519.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 500.85 519.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 506.85 Td (Amounts in Millions, Except Per Share Data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.50 506.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 460.50 506.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.50 506.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 493.17 Td (Net Earnings ) Tj ET Q q 0 0 0 rg BT 93.71 493.17 Td (Attributable to BMS used for Basic and Diluted EPS Calculation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 493.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 493.17 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 493.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.15 493.17 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 493.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 493.17 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 467.17 Td (W) Tj ET Q q 0 0 0 rg BT 48.04 467.17 Td (eighted-average common shares outstanding - basic) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 467.17 Td (1,645) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.15 467.17 Td (1,671) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 467.17 Td (1,667) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 454.17 Td (Incremental shares attributable to share-based compensation plans) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 454.17 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 454.17 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 454.17 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 441.17 Td (W) Tj ET Q q 0 0 0 rg BT 48.04 441.17 Td (eighted-average common shares outstanding - diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.15 441.17 Td (1,652) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.15 441.17 Td (1,680) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 441.17 Td (1,679) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 415.17 Td (Earnings per share - basic) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 415.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.15 415.17 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 415.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 415.17 Td (2.67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 415.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 415.17 Td (0.94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 402.17 Td (Earnings per share - diluted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 402.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.15 402.17 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 402.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 402.17 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 402.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 402.17 Td (0.93) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 373.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 373.10 Td (9) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 63.49 373.10 Td (. FINANCIAL) Tj ET Q q 0 0 0 rg BT 124.61 373.10 Td ( INSTRUMENTS ) Tj ET Q q 0 0 0 rg BT 202.41 373.10 Td (AND F) Tj ET Q q 0 0 0 rg BT 231.94 373.10 Td (AIR ) Tj ET Q q 0 0 0 rg BT 252.59 373.10 Td (V) Tj ET Q q 0 0 0 rg BT 258.52 373.10 Td (ALUE MEASUREMENTS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 75.98 349.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 125.42 349.10 Td (include ) Tj ET Q q 0 0 0 rg BT 157.63 349.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 178.17 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 195.38 349.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 215.92 349.10 Td (equivalents, ) Tj ET Q q 0 0 0 rg BT 266.74 349.10 Td (marketable ) Tj ET Q q 0 0 0 rg BT 313.93 349.10 Td (securities, ) Tj ET Q q 0 0 0 rg BT 356.96 349.10 Td (accounts ) Tj ET Q q 0 0 0 rg BT 394.72 349.10 Td (receivable ) Tj ET Q q 0 0 0 rg BT 438.57 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 455.78 349.10 Td (payable, ) Tj ET Q q 0 0 0 rg BT 492.15 349.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 512.14 349.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 561.58 349.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 337.10 Td (derivatives.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 313.10 Td (Changes ) Tj ET Q q 0 0 0 rg BT 73.89 313.10 Td (in ) Tj ET Q q 0 0 0 rg BT 85.12 313.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 126.33 313.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 148.66 313.10 Td (and ) Tj ET Q q 0 0 0 rg BT 166.55 313.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 199.43 313.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 221.76 313.10 Td (create ) Tj ET Q q 0 0 0 rg BT 249.08 313.10 Td (exposure ) Tj ET Q q 0 0 0 rg BT 288.63 313.10 Td (to ) Tj ET Q q 0 0 0 rg BT 299.86 313.10 Td (market ) Tj ET Q q 0 0 0 rg BT 331.07 313.10 Td (risk. ) Tj ET Q q 0 0 0 rg BT 352.03 313.10 Td (Certain ) Tj ET Q q 0 0 0 rg BT 384.91 313.10 Td (derivative ) Tj ET Q q 0 0 0 rg BT 428.34 313.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 466.78 313.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 516.89 313.10 Td (are ) Tj ET Q q 0 0 0 rg BT 532.55 313.10 Td (used ) Tj ET Q q 0 0 0 rg BT 554.33 313.10 Td (when ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 301.10 Td (available ) Tj ET Q q 0 0 0 rg BT 74.84 301.10 Td (on ) Tj ET Q q 0 0 0 rg BT 87.59 301.10 Td (a ) Tj ET Q q 0 0 0 rg BT 94.78 301.10 Td (cost-ef) Tj ET Q q 0 0 0 rg BT 121.81 301.10 Td (fective ) Tj ET Q q 0 0 0 rg BT 151.76 301.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 174.51 301.10 Td (to ) Tj ET Q q 0 0 0 rg BT 185.04 301.10 Td (hedge ) Tj ET Q q 0 0 0 rg BT 211.67 301.10 Td (the ) Tj ET Q q 0 0 0 rg BT 226.64 301.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 272.72 301.10 Td (economic ) Tj ET Q q 0 0 0 rg BT 314.34 301.10 Td (exposure. ) Tj ET Q q 0 0 0 rg BT 355.49 301.10 Td (These ) Tj ET Q q 0 0 0 rg BT 382.12 301.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 431.54 301.10 Td (qualify ) Tj ET Q q 0 0 0 rg BT 462.61 301.10 Td (as ) Tj ET Q q 0 0 0 rg BT 473.69 301.10 Td (cash ) Tj ET Q q 0 0 0 rg BT 494.21 301.10 Td (flow) Tj ET Q q 0 0 0 rg BT 511.90 301.10 Td (, ) Tj ET Q q 0 0 0 rg BT 517.15 301.10 Td (net ) Tj ET Q q 0 0 0 rg BT 532.11 301.10 Td (investment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 289.10 Td (and ) Tj ET Q q 0 0 0 rg BT 53.68 289.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 70.80 289.10 Td (value ) Tj ET Q q 0 0 0 rg BT 95.69 289.10 Td (hedges ) Tj ET Q q 0 0 0 rg BT 126.70 289.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 149.95 289.10 Td (meeting ) Tj ET Q q 0 0 0 rg BT 185.40 289.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 215.84 289.10 Td (criteria, ) Tj ET Q q 0 0 0 rg BT 249.89 289.10 Td (including ) Tj ET Q q 0 0 0 rg BT 290.91 289.10 Td (ef) Tj ET Q q 0 0 0 rg BT 298.50 289.10 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 346.16 289.10 Td (of ) Tj ET Q q 0 0 0 rg BT 357.73 289.10 Td (of) Tj ET Q q 0 0 0 rg BT 365.88 289.10 Td (fsetting ) Tj ET Q q 0 0 0 rg BT 399.12 289.10 Td (hedged ) Tj ET Q q 0 0 0 rg BT 431.24 289.10 Td (exposures. ) Tj ET Q q 0 0 0 rg BT 476.97 289.10 Td (Changes ) Tj ET Q q 0 0 0 rg BT 514.65 289.10 Td (in ) Tj ET Q q 0 0 0 rg BT 525.67 289.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 542.79 289.10 Td (value ) Tj ET Q q 0 0 0 rg BT 567.68 289.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 277.10 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 82.73 277.10 Td (that ) Tj ET Q q 0 0 0 rg BT 100.59 277.10 Td (do ) Tj ET Q q 0 0 0 rg BT 113.45 277.10 Td (not ) Tj ET Q q 0 0 0 rg BT 129.09 277.10 Td (qualify ) Tj ET Q q 0 0 0 rg BT 160.28 277.10 Td (for ) Tj ET Q q 0 0 0 rg BT 174.80 277.10 Td (hedge ) Tj ET Q q 0 0 0 rg BT 201.54 277.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 248.27 277.10 Td (are ) Tj ET Q q 0 0 0 rg BT 263.34 277.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 310.06 277.10 Td (in ) Tj ET Q q 0 0 0 rg BT 320.70 277.10 Td (earnings ) Tj ET Q q 0 0 0 rg BT 357.44 277.10 Td (as ) Tj ET Q q 0 0 0 rg BT 368.63 277.10 Td (they ) Tj ET Q q 0 0 0 rg BT 388.71 277.10 Td (occur) Tj ET Q q 0 0 0 rg BT 410.37 277.10 Td (. ) Tj ET Q q 0 0 0 rg BT 415.73 277.10 Td (Derivative ) Tj ET Q q 0 0 0 rg BT 460.79 277.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 498.63 277.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 548.16 277.10 Td (are ) Tj ET Q q 0 0 0 rg BT 563.23 277.10 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 265.10 Td (used ) Tj ET Q q 0 0 0 rg BT 56.83 265.10 Td (for ) Tj ET Q q 0 0 0 rg BT 70.99 265.10 Td (trading ) Tj ET Q q 0 0 0 rg BT 101.82 265.10 Td (purposes.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.10 Td (Financial ) Tj ET Q q 0 0 0 rg BT 74.73 241.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 122.91 241.10 Td (are ) Tj ET Q q 0 0 0 rg BT 136.63 241.10 Td (subject ) Tj ET Q q 0 0 0 rg BT 166.47 241.10 Td (to ) Tj ET Q q 0 0 0 rg BT 175.77 241.10 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 227.82 241.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 252.10 241.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 268.61 241.10 Td (which ) Tj ET Q q 0 0 0 rg BT 294.57 241.10 Td (is ) Tj ET Q q 0 0 0 rg BT 302.75 241.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 347.58 241.10 Td (as ) Tj ET Q q 0 0 0 rg BT 357.43 241.10 Td (part ) Tj ET Q q 0 0 0 rg BT 374.49 241.10 Td (of ) Tj ET Q q 0 0 0 rg BT 384.34 241.10 Td (the ) Tj ET Q q 0 0 0 rg BT 398.07 241.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 427.35 241.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 442.75 241.10 Td (value ) Tj ET Q q 0 0 0 rg BT 465.92 241.10 Td (measurement. ) Tj ET Q q 0 0 0 rg BT 523.24 241.10 Td (Counterparty ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 229.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 61.51 229.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 79.25 229.10 Td (is ) Tj ET Q q 0 0 0 rg BT 88.66 229.10 Td (monitored ) Tj ET Q q 0 0 0 rg BT 132.50 229.10 Td (on ) Tj ET Q q 0 0 0 rg BT 145.25 229.10 Td (an ) Tj ET Q q 0 0 0 rg BT 157.43 229.10 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 192.95 229.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 215.69 229.10 Td (and ) Tj ET Q q 0 0 0 rg BT 232.87 229.10 Td (mitigated ) Tj ET Q q 0 0 0 rg BT 273.38 229.10 Td (by ) Tj ET Q q 0 0 0 rg BT 286.12 229.10 Td (limiting ) Tj ET Q q 0 0 0 rg BT 320.53 229.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 357.16 229.10 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 406.57 229.10 Td (with ) Tj ET Q q 0 0 0 rg BT 427.09 229.10 Td (any ) Tj ET Q q 0 0 0 rg BT 444.27 229.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 487.56 229.10 Td (counterparty) Tj ET Q q 0 0 0 rg BT 537.44 229.10 Td (, ) Tj ET Q q 0 0 0 rg BT 542.68 229.10 Td (utilizing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 217.10 Td (conventional ) Tj ET Q q 0 0 0 rg BT 89.10 217.10 Td (derivative ) Tj ET Q q 0 0 0 rg BT 130.53 217.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 166.97 217.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 215.08 217.10 Td (and ) Tj ET Q q 0 0 0 rg BT 230.97 217.10 Td (only ) Tj ET Q q 0 0 0 rg BT 250.20 217.10 Td (entering ) Tj ET Q q 0 0 0 rg BT 284.42 217.10 Td (into ) Tj ET Q q 0 0 0 rg BT 301.43 217.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 348.41 217.10 Td (with ) Tj ET Q q 0 0 0 rg BT 367.64 217.10 Td (counterparties ) Tj ET Q q 0 0 0 rg BT 425.73 217.10 Td (that ) Tj ET Q q 0 0 0 rg BT 442.18 217.10 Td (meet ) Tj ET Q q 0 0 0 rg BT 463.06 217.10 Td (high ) Tj ET Q q 0 0 0 rg BT 482.29 217.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 506.51 217.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 535.74 217.10 Td (standards. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 205.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.10 205.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 107.20 205.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 144.73 205.10 Td (statements ) Tj ET Q q 0 0 0 rg BT 189.50 205.10 Td (would ) Tj ET Q q 0 0 0 rg BT 217.05 205.10 Td (not ) Tj ET Q q 0 0 0 rg BT 232.38 205.10 Td (be ) Tj ET Q q 0 0 0 rg BT 244.37 205.10 Td (materially ) Tj ET Q q 0 0 0 rg BT 287.46 205.10 Td (impacted ) Tj ET Q q 0 0 0 rg BT 326.67 205.10 Td (if ) Tj ET Q q 0 0 0 rg BT 335.33 205.10 Td (any ) Tj ET Q q 0 0 0 rg BT 352.32 205.10 Td (counterparty ) Tj ET Q q 0 0 0 rg BT 405.41 205.10 Td (failed ) Tj ET Q q 0 0 0 rg BT 430.73 205.10 Td (to ) Tj ET Q q 0 0 0 rg BT 441.06 205.10 Td (perform ) Tj ET Q q 0 0 0 rg BT 475.82 205.10 Td (according ) Tj ET Q q 0 0 0 rg BT 517.80 205.10 Td (to ) Tj ET Q q 0 0 0 rg BT 528.13 205.10 Td (the ) Tj ET Q q 0 0 0 rg BT 542.90 205.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 567.67 205.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 193.10 Td (its ) Tj ET Q q 0 0 0 rg BT 48.85 193.10 Td (agreement. ) Tj ET Q q 0 0 0 rg BT 96.40 193.10 Td (Collateral ) Tj ET Q q 0 0 0 rg BT 139.23 193.10 Td (is ) Tj ET Q q 0 0 0 rg BT 149.30 193.10 Td (not ) Tj ET Q q 0 0 0 rg BT 165.48 193.10 Td (required ) Tj ET Q q 0 0 0 rg BT 202.20 193.10 Td (by ) Tj ET Q q 0 0 0 rg BT 215.60 193.10 Td (any ) Tj ET Q q 0 0 0 rg BT 233.45 193.10 Td (party ) Tj ET Q q 0 0 0 rg BT 257.40 193.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 293.01 193.10 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 340.28 193.10 Td (are ) Tj ET Q q 0 0 0 rg BT 355.89 193.10 Td (in ) Tj ET Q q 0 0 0 rg BT 367.07 193.10 Td (an ) Tj ET Q q 0 0 0 rg BT 379.92 193.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 402.76 193.10 Td (or ) Tj ET Q q 0 0 0 rg BT 414.49 193.10 Td (liability ) Tj ET Q q 0 0 0 rg BT 449.00 193.10 Td (position ) Tj ET Q q 0 0 0 rg BT 484.63 193.10 Td (under ) Tj ET Q q 0 0 0 rg BT 510.80 193.10 Td (the ) Tj ET Q q 0 0 0 rg BT 526.42 193.10 Td (terms ) Tj ET Q q 0 0 0 rg BT 552.04 193.10 Td (of ) Tj ET Q q 0 0 0 rg BT 563.78 193.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.10 Td (agreements.) Tj ET Q endstream endobj 171 0 obj <> endobj 172 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (85) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Fair V) Tj ET Q q 0 0 0 rg BT 61.28 749.10 Td (alue Measur) Tj ET Q q 0 0 0 rg BT 111.18 749.10 Td (ements –) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 146.44 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 148.76 749.10 Td (The fair value of financial instruments are classified into one of the following categories:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 732.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 87.38 732.10 Td (1 ) Tj ET Q q 0 0 0 rg BT 93.99 732.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 120.06 732.10 Td (utilize ) Tj ET Q q 0 0 0 rg BT 146.66 732.10 Td (unadjusted ) Tj ET Q q 0 0 0 rg BT 191.60 732.10 Td (quoted ) Tj ET Q q 0 0 0 rg BT 220.44 732.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 245.93 732.10 Td (in ) Tj ET Q q 0 0 0 rg BT 255.32 732.10 Td (active ) Tj ET Q q 0 0 0 rg BT 280.81 732.10 Td (markets ) Tj ET Q q 0 0 0 rg BT 314.08 732.10 Td (accessible ) Tj ET Q q 0 0 0 rg BT 356.23 732.10 Td (at ) Tj ET Q q 0 0 0 rg BT 365.06 732.10 Td (the ) Tj ET Q q 0 0 0 rg BT 378.89 732.10 Td (measurement ) Tj ET Q q 0 0 0 rg BT 433.82 732.10 Td (date ) Tj ET Q q 0 0 0 rg BT 452.09 732.10 Td (for ) Tj ET Q q 0 0 0 rg BT 465.36 732.10 Td (identical ) Tj ET Q q 0 0 0 rg BT 501.41 732.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 526.35 732.10 Td (or ) Tj ET Q q 0 0 0 rg BT 536.30 732.10 Td (liabilities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 720.10 Td (The ) Tj ET Q q 0 0 0 rg BT 81.05 720.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 97.42 720.10 Td (value ) Tj ET Q q 0 0 0 rg BT 121.58 720.10 Td (hierarchy ) Tj ET Q q 0 0 0 rg BT 161.83 720.10 Td (provides ) Tj ET Q q 0 0 0 rg BT 198.77 720.10 Td (the ) Tj ET Q q 0 0 0 rg BT 213.49 720.10 Td (highest ) Tj ET Q q 0 0 0 rg BT 244.88 720.10 Td (priority ) Tj ET Q q 0 0 0 rg BT 277.37 720.10 Td (to ) Tj ET Q q 0 0 0 rg BT 287.65 720.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 312.91 720.10 Td (1 ) Tj ET Q q 0 0 0 rg BT 320.41 720.10 Td (inputs. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 696.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 87.88 696.10 Td (2 ) Tj ET Q q 0 0 0 rg BT 95.00 696.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 121.57 696.10 Td (utilize ) Tj ET Q q 0 0 0 rg BT 148.68 696.10 Td (observable ) Tj ET Q q 0 0 0 rg BT 194.11 696.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 220.11 696.10 Td (for ) Tj ET Q q 0 0 0 rg BT 233.89 696.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 263.78 696.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 312.57 696.10 Td (and ) Tj ET Q q 0 0 0 rg BT 329.12 696.10 Td (quoted ) Tj ET Q q 0 0 0 rg BT 358.46 696.10 Td (prices ) Tj ET Q q 0 0 0 rg BT 384.46 696.10 Td (for ) Tj ET Q q 0 0 0 rg BT 398.23 696.10 Td (identical ) Tj ET Q q 0 0 0 rg BT 434.78 696.10 Td (or ) Tj ET Q q 0 0 0 rg BT 445.23 696.10 Td (similar ) Tj ET Q q 0 0 0 rg BT 475.12 696.10 Td (instruments ) Tj ET Q q 0 0 0 rg BT 523.91 696.10 Td (in ) Tj ET Q q 0 0 0 rg BT 533.81 696.10 Td (non-active ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 684.10 Td (markets. ) Tj ET Q q 0 0 0 rg BT 100.92 684.10 Td (Additionally) Tj ET Q q 0 0 0 rg BT 150.82 684.10 Td (, ) Tj ET Q q 0 0 0 rg BT 158.15 684.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 190.19 684.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 232.77 684.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 254.82 684.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 297.41 684.10 Td (utilize ) Tj ET Q q 0 0 0 rg BT 327.23 684.10 Td (a ) Tj ET Q q 0 0 0 rg BT 336.50 684.10 Td (third-party ) Tj ET Q q 0 0 0 rg BT 384.10 684.10 Td (matrix ) Tj ET Q q 0 0 0 rg BT 415.03 684.10 Td (pricing ) Tj ET Q q 0 0 0 rg BT 448.19 684.10 Td (model ) Tj ET Q q 0 0 0 rg BT 478.01 684.10 Td (using ) Tj ET Q q 0 0 0 rg BT 504.51 684.10 Td (significant ) Tj ET Q q 0 0 0 rg BT 551.55 684.10 Td (inputs ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 672.10 Td (corroborated ) Tj ET Q q 0 0 0 rg BT 116.62 672.10 Td (by ) Tj ET Q q 0 0 0 rg BT 129.15 672.10 Td (market ) Tj ET Q q 0 0 0 rg BT 159.45 672.10 Td (data ) Tj ET Q q 0 0 0 rg BT 178.64 672.10 Td (for ) Tj ET Q q 0 0 0 rg BT 192.83 672.10 Td (substantially ) Tj ET Q q 0 0 0 rg BT 245.91 672.10 Td (the ) Tj ET Q q 0 0 0 rg BT 260.66 672.10 Td (full ) Tj ET Q q 0 0 0 rg BT 277.08 672.10 Td (term ) Tj ET Q q 0 0 0 rg BT 297.94 672.10 Td (of ) Tj ET Q q 0 0 0 rg BT 308.81 672.10 Td (the ) Tj ET Q q 0 0 0 rg BT 323.56 672.10 Td (assets. ) Tj ET Q q 0 0 0 rg BT 351.92 672.10 Td (Equity ) Tj ET Q q 0 0 0 rg BT 381.12 672.10 Td (and ) Tj ET Q q 0 0 0 rg BT 398.09 672.10 Td (fixed ) Tj ET Q q 0 0 0 rg BT 421.17 672.10 Td (income ) Tj ET Q q 0 0 0 rg BT 453.14 672.10 Td (funds ) Tj ET Q q 0 0 0 rg BT 477.89 672.10 Td (are ) Tj ET Q q 0 0 0 rg BT 492.63 672.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 532.38 672.10 Td (invested ) Tj ET Q q 0 0 0 rg BT 568.23 672.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 660.10 Td (publicly ) Tj ET Q q 0 0 0 rg BT 98.66 660.10 Td (traded ) Tj ET Q q 0 0 0 rg BT 126.52 660.10 Td (securities ) Tj ET Q q 0 0 0 rg BT 167.17 660.10 Td (valued ) Tj ET Q q 0 0 0 rg BT 196.71 660.10 Td (at ) Tj ET Q q 0 0 0 rg BT 206.81 660.10 Td (the ) Tj ET Q q 0 0 0 rg BT 221.91 660.10 Td (respective ) Tj ET Q q 0 0 0 rg BT 265.32 660.10 Td (net ) Tj ET Q q 0 0 0 rg BT 280.42 660.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 302.74 660.10 Td (value ) Tj ET Q q 0 0 0 rg BT 327.28 660.10 Td (of ) Tj ET Q q 0 0 0 rg BT 338.49 660.10 Td (the ) Tj ET Q q 0 0 0 rg BT 353.59 660.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 399.80 660.10 Td (investments. ) Tj ET Q q 0 0 0 rg BT 452.95 660.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 478.60 660.10 Td (2 ) Tj ET Q q 0 0 0 rg BT 486.48 660.10 Td (derivative ) Tj ET Q q 0 0 0 rg BT 529.34 660.10 Td (instruments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 648.10 Td (are ) Tj ET Q q 0 0 0 rg BT 78.40 648.10 Td (valued ) Tj ET Q q 0 0 0 rg BT 108.25 648.10 Td (using ) Tj ET Q q 0 0 0 rg BT 133.11 648.10 Td (LIBOR ) Tj ET Q q 0 0 0 rg BT 166.31 648.10 Td (yield ) Tj ET Q q 0 0 0 rg BT 189.49 648.10 Td (curves, ) Tj ET Q q 0 0 0 rg BT 221.29 648.10 Td (less ) Tj ET Q q 0 0 0 rg BT 239.48 648.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 265.44 648.10 Td (valuation ) Tj ET Q q 0 0 0 rg BT 305.84 648.10 Td (adjustments, ) Tj ET Q q 0 0 0 rg BT 359.31 648.10 Td (and ) Tj ET Q q 0 0 0 rg BT 376.94 648.10 Td (observable ) Tj ET Q q 0 0 0 rg BT 423.45 648.10 Td (forward ) Tj ET Q q 0 0 0 rg BT 458.29 648.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 490.36 648.10 Td (exchange ) Tj ET Q q 0 0 0 rg BT 531.31 648.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 553.38 648.10 Td (at ) Tj ET Q q 0 0 0 rg BT 563.79 648.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 636.10 Td (reporting ) Tj ET Q q 0 0 0 rg BT 102.08 636.10 Td (date. ) Tj ET Q q 0 0 0 rg BT 123.49 636.10 Td (V) Tj ET Q q 0 0 0 rg BT 129.60 636.10 Td (aluations ) Tj ET Q q 0 0 0 rg BT 168.13 636.10 Td (of ) Tj ET Q q 0 0 0 rg BT 178.89 636.10 Td (derivative ) Tj ET Q q 0 0 0 rg BT 221.30 636.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 259.82 636.10 Td (may ) Tj ET Q q 0 0 0 rg BT 279.46 636.10 Td (fluctuate ) Tj ET Q q 0 0 0 rg BT 316.87 636.10 Td (considerably ) Tj ET Q q 0 0 0 rg BT 370.39 636.10 Td (from ) Tj ET Q q 0 0 0 rg BT 392.25 636.10 Td (volatility ) Tj ET Q q 0 0 0 rg BT 430.79 636.10 Td (in ) Tj ET Q q 0 0 0 rg BT 440.99 636.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 486.75 636.10 Td (foreign ) Tj ET Q q 0 0 0 rg BT 518.05 636.10 Td (currencies ) Tj ET Q q 0 0 0 rg BT 561.56 636.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 624.10 Td (underlying ) Tj ET Q q 0 0 0 rg BT 108.83 624.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 140.76 624.10 Td (rates ) Tj ET Q q 0 0 0 rg BT 162.14 624.10 Td (driven ) Tj ET Q q 0 0 0 rg BT 190.18 624.10 Td (by ) Tj ET Q q 0 0 0 rg BT 202.68 624.10 Td (market ) Tj ET Q q 0 0 0 rg BT 232.95 624.10 Td (conditions ) Tj ET Q q 0 0 0 rg BT 277.11 624.10 Td (and ) Tj ET Q q 0 0 0 rg BT 294.05 624.10 Td (the ) Tj ET Q q 0 0 0 rg BT 308.77 624.10 Td (duration ) Tj ET Q q 0 0 0 rg BT 344.59 624.10 Td (of ) Tj ET Q q 0 0 0 rg BT 355.42 624.10 Td (the ) Tj ET Q q 0 0 0 rg BT 370.14 624.10 Td (contract. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 600.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 87.80 600.10 Td (3 ) Tj ET Q q 0 0 0 rg BT 94.83 600.10 Td (unobservable ) Tj ET Q q 0 0 0 rg BT 150.18 600.10 Td (inputs ) Tj ET Q q 0 0 0 rg BT 176.66 600.10 Td (are ) Tj ET Q q 0 0 0 rg BT 190.90 600.10 Td (used ) Tj ET Q q 0 0 0 rg BT 211.26 600.10 Td (when ) Tj ET Q q 0 0 0 rg BT 234.95 600.10 Td (little ) Tj ET Q q 0 0 0 rg BT 255.32 600.10 Td (or ) Tj ET Q q 0 0 0 rg BT 265.68 600.10 Td (no ) Tj ET Q q 0 0 0 rg BT 277.71 600.10 Td (market ) Tj ET Q q 0 0 0 rg BT 307.51 600.10 Td (data ) Tj ET Q q 0 0 0 rg BT 326.20 600.10 Td (is ) Tj ET Q q 0 0 0 rg BT 334.90 600.10 Td (available. ) Tj ET Q q 0 0 0 rg BT 375.37 600.10 Td (There ) Tj ET Q q 0 0 0 rg BT 400.72 600.10 Td (were ) Tj ET Q q 0 0 0 rg BT 422.18 600.10 Td (no ) Tj ET Q q 0 0 0 rg BT 434.22 600.10 Td (Level ) Tj ET Q q 0 0 0 rg BT 459.01 600.10 Td (3 ) Tj ET Q q 0 0 0 rg BT 466.04 600.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 503.06 600.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 528.42 600.10 Td (or ) Tj ET Q q 0 0 0 rg BT 538.78 600.10 Td (liabilities ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 588.10 Td (as ) Tj ET Q q 0 0 0 rg BT 73.83 588.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 84.66 588.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 143.24 588.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 163.24 588.10 Td ( ) Tj ET Q q 0 0 0 rg BT 165.74 588.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 182.68 588.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.68 588.10 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 564.10 Td (Financial assets and liabilities measured at fair value on a recurring basis are summarized below:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 525.60 384.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 420.50 525.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 525.60 35.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 525.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 525.60 35.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 498.50 525.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 525.60 35.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 537.50 525.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 541.50 525.60 35.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 497.60 384.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 420.50 497.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 497.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 497.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 497.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 498.50 497.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 497.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 537.50 497.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 541.50 497.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 471.60 384.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 420.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 471.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 471.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 498.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 471.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 537.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 541.50 471.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 445.60 384.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 420.50 445.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 445.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 445.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 445.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 498.50 445.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 445.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 537.50 445.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 541.50 445.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 419.60 384.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 420.50 419.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 419.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 459.50 419.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 463.50 419.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 498.50 419.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 419.60 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 537.50 419.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 541.50 419.60 35.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 424.5 538.6 m 459.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 459.5 538.6 m 463.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 463.5 538.6 m 498.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 502.5 538.6 m 537.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 537.5 538.6 m 541.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 541.5 538.6 m 576.5 538.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 424.5 525.6 m 459.5 525.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 463.5 525.6 m 498.5 525.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 502.5 525.6 m 537.5 525.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 541.5 525.6 m 576.5 525.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 428.75 542.83 Td (December) Tj ET Q q 0 0 0 rg BT 463.32 542.83 Td ( 31, 2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 506.75 542.83 Td (December) Tj ET Q q 0 0 0 rg BT 541.32 542.83 Td ( 31, 2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 529.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 429.15 529.83 Td (Level 1) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 468.15 529.83 Td (Level 2) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 507.15 529.83 Td (Level 1) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 546.15 529.83 Td (Level 2) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 45.00 516.33 Td (Cash and cash equivalents - Money market and other) Tj ET Q q 0 0 0 rg BT 272.70 516.33 Td ( securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 427.00 515.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 515.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.00 515.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.10 515.27 Td (4,728) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 505.00 515.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 515.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 544.00 515.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.10 515.27 Td (3,532) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 45.00 501.33 Td (Marketable securities:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 488.17 Td (Certificates of deposit) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 488.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.60 488.17 Td (141) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 488.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 488.17 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 475.17 Td (Commercial paper) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 475.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 475.17 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 475.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.60 475.17 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 462.17 Td (Corporate debt securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 462.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.10 462.17 Td (3,548) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 462.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.10 462.17 Td (3,947) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 449.17 Td (Equity funds) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 449.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.60 449.17 Td (124) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 449.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.60 449.17 Td (101) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 436.17 Td (Fixed income funds) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 436.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 436.17 Td (8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 436.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 436.17 Td (7) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 45.00 423.33 Td (Derivative assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 423.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 423.17 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 423.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 423.17 Td (75) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 45.00 410.33 Td (Equity investments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 410.17 Td (67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 410.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 410.17 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 410.17 Td (—) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 45.00 397.33 Td (Derivative liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 445.65 397.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.30 397.22 Td (\(52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 397.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.65 397.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 397.17 Td (\(30) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 397.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 370.10 Td (Equity ) Tj ET Q q 0 0 0 rg BT 65.08 370.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 115.27 370.10 Td (not ) Tj ET Q q 0 0 0 rg BT 130.47 370.10 Td (measured ) Tj ET Q q 0 0 0 rg BT 171.20 370.10 Td (at ) Tj ET Q q 0 0 0 rg BT 180.83 370.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 197.13 370.10 Td (value ) Tj ET Q q 0 0 0 rg BT 221.20 370.10 Td (at ) Tj ET Q q 0 0 0 rg BT 230.83 370.10 Td (year ) Tj ET Q q 0 0 0 rg BT 250.46 370.10 Td (end ) Tj ET Q q 0 0 0 rg BT 267.31 370.10 Td (and ) Tj ET Q q 0 0 0 rg BT 284.17 370.10 Td (excluded ) Tj ET Q q 0 0 0 rg BT 322.68 370.10 Td (from ) Tj ET Q q 0 0 0 rg BT 344.54 370.10 Td (the ) Tj ET Q q 0 0 0 rg BT 359.17 370.10 Td (above ) Tj ET Q q 0 0 0 rg BT 385.46 370.10 Td (table ) Tj ET Q q 0 0 0 rg BT 407.31 370.10 Td (were ) Tj ET Q q 0 0 0 rg BT 429.16 370.10 Td (limited ) Tj ET Q q 0 0 0 rg BT 459.91 370.10 Td (partnerships ) Tj ET Q q 0 0 0 rg BT 511.20 370.10 Td (and ) Tj ET Q q 0 0 0 rg BT 528.06 370.10 Td (other ) Tj ET Q q 0 0 0 rg BT 551.02 370.10 Td (equity ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 358.10 Td (method ) Tj ET Q q 0 0 0 rg BT 67.92 358.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 117.61 358.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 127.86 358.10 Td ($66 ) Tj ET Q q 0 0 0 rg BT 144.78 358.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 173.68 358.10 Td ( ) Tj ET Q q 0 0 0 rg BT 175.60 358.10 Td (in ) Tj ET Q q 0 0 0 rg BT 185.30 358.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 207.22 358.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.58 358.10 Td ($37 ) Tj ET Q q 0 0 0 rg BT 240.50 358.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.39 358.10 Td ( ) Tj ET Q q 0 0 0 rg BT 271.31 358.10 Td (in ) Tj ET Q q 0 0 0 rg BT 281.01 358.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 302.93 358.10 Td (and ) Tj ET Q q 0 0 0 rg BT 319.29 358.10 Td (other ) Tj ET Q q 0 0 0 rg BT 341.76 358.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 368.68 358.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 418.37 358.10 Td (without ) Tj ET Q q 0 0 0 rg BT 450.85 358.10 Td (readily ) Tj ET Q q 0 0 0 rg BT 480.54 358.10 Td (determinable ) Tj ET Q q 0 0 0 rg BT 534.65 358.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 550.45 358.10 Td (values ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 346.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 46.83 346.10 Td ($152 ) Tj ET Q q 0 0 0 rg BT 69.33 346.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 98.22 346.10 Td ( ) Tj ET Q q 0 0 0 rg BT 100.72 346.10 Td (in ) Tj ET Q q 0 0 0 rg BT 111.00 346.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 133.50 346.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 150.44 346.10 Td ($8 ) Tj ET Q q 0 0 0 rg BT 162.94 346.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 191.83 346.10 Td ( ) Tj ET Q q 0 0 0 rg BT 194.33 346.10 Td (in ) Tj ET Q q 0 0 0 rg BT 204.61 346.10 Td (2016. ) Tj ET Q q 0 0 0 rg BT 229.43 346.10 Td (These ) Tj ET Q q 0 0 0 rg BT 255.80 346.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 292.19 346.10 Td (are ) Tj ET Q q 0 0 0 rg BT 306.90 346.10 Td (included ) Tj ET Q q 0 0 0 rg BT 343.83 346.10 Td (in ) Tj ET Q q 0 0 0 rg BT 354.11 346.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 379.38 346.10 Td (assets.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 322.10 Td (A) Tj ET Q q 0 0 0 rg BT 41.56 322.10 Td (vailable-for) Tj ET Q q 0 0 0 rg BT 88.57 322.10 Td (-sale Securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 300.50 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 300.50 Td (following ) Tj ET Q q 0 0 0 rg BT 95.43 300.50 Td (table ) Tj ET Q q 0 0 0 rg BT 117.37 300.50 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 167.63 300.50 Td (available-for) Tj ET Q q 0 0 0 rg BT 218.51 300.50 Td (-sale ) Tj ET Q q 0 0 0 rg BT 239.89 300.50 Td (securities:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 251.00 134.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 170.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 216.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 220.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 266.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 251.00 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 251.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 251.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 225.00 134.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 170.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 216.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 220.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 266.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 225.00 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 225.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 225.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 199.00 134.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 170.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 216.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 220.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 266.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 199.00 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 199.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 199.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 181.00 280.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 181.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 181.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 181.00 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 181.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 181.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 181.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 181.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 181.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 181.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 181.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 155.00 134.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 170.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 216.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 220.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 266.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 316.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 320.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 155.00 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 155.00 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 155.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 155.00 46.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 170.5 277 m 216.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 216.5 277 m 220.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 277 m 266.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 266.5 277 m 270.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 277 m 316.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 316.5 277 m 320.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 277 m 366.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 277 m 426.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 426.5 277 m 430.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 277 m 476.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 476.5 277 m 480.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 277 m 526.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 277 m 530.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 277 m 576.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 264 m 266.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 266.5 264 m 270.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 264 m 316.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 277 m 366.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 277 m 426.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 426.5 277 m 430.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 277 m 476.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 264 m 476.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 476.5 277 m 480.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 476.5 264 m 480.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 277 m 526.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 264 m 526.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 277 m 530.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 277 m 576.5 277 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 170.5 251 m 216.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 264 m 266.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 251 m 266.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 264 m 316.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 251 m 316.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 251 m 366.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 251 m 426.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 264 m 476.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 251 m 476.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 264 m 526.5 264 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 251 m 526.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 251 m 576.5 251 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 199 m 426.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 199 m 476.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 199 m 526.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 170.5 199 m 216.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 170.5 187 m 216.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 170.5 185 m 216.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 199 m 266.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 187 m 266.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 220.5 185 m 266.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 199 m 316.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 187 m 316.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 270.5 185 m 316.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 199 m 366.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 186 m 366.5 186 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 199 m 426.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 187 m 426.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 185 m 426.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 199 m 476.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 187 m 476.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 185 m 476.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 199 m 526.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 187 m 526.5 187 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 185 m 526.5 185 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 199 m 576.5 199 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 186 m 576.5 186 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 155 m 366.5 155 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 155 m 576.5 155 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 155 m 366.5 155 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 143 m 366.5 143 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 320.5 141 m 366.5 141 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 155 m 576.5 155 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 143 m 576.5 143 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 141 m 576.5 141 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 235.75 281.23 Td (December) Tj ET Q q 0 0 0 rg BT 270.32 281.23 Td ( 31, 2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 445.75 281.23 Td (December) Tj ET Q q 0 0 0 rg BT 480.32 281.23 Td ( 31, 2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 255.25 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 174.75 263.23 Td (Amortized) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 185.20 255.23 Td (Cost) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 238.45 268.23 Td (Gr) Tj ET Q q 0 0 0 rg BT 248.15 268.23 Td (oss Unr) Tj ET Q q 0 0 0 rg BT 274.01 268.23 Td (ealized) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 325.15 255.23 Td (Fair) Tj ET Q q 0 0 0 rg BT 339.74 255.23 Td ( ) Tj ET Q q 0 0 0 rg BT 341.59 255.23 Td (V) Tj ET Q q 0 0 0 rg BT 346.93 255.23 Td (alue) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.75 263.23 Td (Amortized) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 395.20 255.23 Td (Cost) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 448.45 268.23 Td (Gr) Tj ET Q q 0 0 0 rg BT 458.15 268.23 Td (oss Unr) Tj ET Q q 0 0 0 rg BT 484.01 268.23 Td (ealized) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 535.15 255.23 Td (Fair) Tj ET Q q 0 0 0 rg BT 549.74 255.23 Td ( ) Tj ET Q q 0 0 0 rg BT 551.59 255.23 Td (V) Tj ET Q q 0 0 0 rg BT 556.93 255.23 Td (alue) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 232.95 255.23 Td (Gains) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 281.85 255.23 Td (Losses) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 442.95 255.23 Td (Gains) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 491.85 255.23 Td (Losses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 241.57 Td (Certificates of deposit) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 173.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 197.65 241.57 Td (141) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.65 241.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 273.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.65 241.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 241.57 Td (141) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 241.57 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 241.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 241.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 241.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 241.57 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 228.57 Td (Commercial paper) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.65 228.57 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.65 228.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.65 228.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.65 228.57 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 228.57 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 228.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 228.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 228.57 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 215.57 Td (Corporate debt securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 190.15 215.57 Td (3,555) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 257.65 215.57 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 299.30 215.62 Td (\(10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.65 215.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 215.57 Td (3,548) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 215.57 Td (3,945) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 215.57 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.30 215.62 Td (\(8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 215.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 215.57 Td (3,947) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 202.57 Td (Equity investments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.65 202.57 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.65 202.57 Td (37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.30 202.62 Td (\(1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.65 202.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.65 202.57 Td (67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 202.57 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 202.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.30 202.62 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 202.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 202.57 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 173.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 190.15 189.57 Td (3,777) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 252.65 189.57 Td (40) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 273.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 299.30 189.62 Td (\(1) Tj ET Q q 0 0 0 rg BT 307.63 189.62 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.65 189.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 189.57 Td (3,806) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.15 189.57 Td (4,753) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 189.57 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.30 189.62 Td (\(15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 189.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 189.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 189.57 Td (4,748) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 171.73 Td (Financial assets measur) Tj ET Q q 0 0 0 rg BT 139.93 171.73 Td (ed using the fair) Tj ET Q q 0 0 0 rg BT 208.92 171.73 Td ( value option) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 158.57 Td (Equity and fixed income funds) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 162.31 163.10 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 158.57 Td (132) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 158.57 Td (108) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 145.57 Td (T) Tj ET Q q 0 0 0 rg BT 62.41 145.57 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.00 145.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 340.15 145.57 Td (3,938) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 145.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 145.57 Td (4,856) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 173 0 obj <> endobj 174 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (86) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 734.50 408.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 734.50 64.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 734.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 734.50 64.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 708.50 408.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 443.50 708.50 64.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 708.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 511.50 708.50 64.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 734.5 m 507.5 734.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 734.5 m 575.5 734.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 734.5 m 507.5 734.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 734.5 m 575.5 734.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 695.5 m 507.5 695.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 683.5 m 507.5 683.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 443.5 681.5 m 507.5 681.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 695.5 m 575.5 695.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 683.5 m 575.5 683.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 511.5 681.5 m 575.5 681.5 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 738.75 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 451.75 746.73 Td (December) Tj ET Q q 0 0 0 rg BT 486.32 746.73 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 467.00 738.73 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 519.75 746.73 Td (December) Tj ET Q q 0 0 0 rg BT 554.25 746.73 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 535.00 738.73 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 725.07 Td (Current marketable securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.00 725.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 725.07 Td (1,391) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.00 725.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 725.07 Td (2,1) Tj ET Q q 0 0 0 rg BT 561.65 725.07 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 712.07 Td (Non-current marketable securities) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 174.05 716.60 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 712.07 Td (2,480) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 712.07 Td (2,719) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 699.07 Td (Other assets) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 86.60 703.60 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 699.07 Td (67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 699.07 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 59.00 686.07 Td (T) Tj ET Q q 0 0 0 rg BT 64.41 686.07 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 446.00 686.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 686.07 Td (3,938) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 514.00 686.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 686.07 Td (4,856) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 667.40 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 49.50 667.40 Td (The ) Tj ET Q q 0 0 0 rg BT 64.01 667.40 Td (fair ) Tj ET Q q 0 0 0 rg BT 77.18 667.40 Td (value ) Tj ET Q q 0 0 0 rg BT 96.58 667.40 Td (option ) Tj ET Q q 0 0 0 rg BT 119.10 667.40 Td (for ) Tj ET Q q 0 0 0 rg BT 130.50 667.40 Td (financial ) Tj ET Q q 0 0 0 rg BT 160.55 667.40 Td (assets ) Tj ET Q q 0 0 0 rg BT 181.29 667.40 Td (was ) Tj ET Q q 0 0 0 rg BT 195.80 667.40 Td (elected ) Tj ET Q q 0 0 0 rg BT 220.53 667.40 Td (for ) Tj ET Q q 0 0 0 rg BT 231.93 667.40 Td (investments ) Tj ET Q q 0 0 0 rg BT 272.22 667.40 Td (in ) Tj ET Q q 0 0 0 rg BT 280.51 667.40 Td (equity ) Tj ET Q q 0 0 0 rg BT 302.58 667.40 Td (and ) Tj ET Q q 0 0 0 rg BT 316.20 667.40 Td (fixed ) Tj ET Q q 0 0 0 rg BT 334.71 667.40 Td (income ) Tj ET Q q 0 0 0 rg BT 360.33 667.40 Td (funds ) Tj ET Q q 0 0 0 rg BT 380.18 667.40 Td (and ) Tj ET Q q 0 0 0 rg BT 393.80 667.40 Td (are ) Tj ET Q q 0 0 0 rg BT 405.64 667.40 Td (included ) Tj ET Q q 0 0 0 rg BT 435.26 667.40 Td (in ) Tj ET Q q 0 0 0 rg BT 443.56 667.40 Td (current ) Tj ET Q q 0 0 0 rg BT 468.28 667.40 Td (marketable ) Tj ET Q q 0 0 0 rg BT 505.89 667.40 Td (securities. ) Tj ET Q q 0 0 0 rg BT 540.17 667.40 Td (Changes ) Tj ET Q q 0 0 0 rg BT 569.79 667.40 Td (in ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 49.50 657.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 62.60 657.80 Td (value ) Tj ET Q q 0 0 0 rg BT 81.93 657.80 Td (were ) Tj ET Q q 0 0 0 rg BT 99.47 657.80 Td (not ) Tj ET Q q 0 0 0 rg BT 111.69 657.80 Td (significant.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 648.25 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 49.50 648.25 Td (All non-current marketable securities mature within five years as of ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 268.09 648.25 Td (December 31, 2017) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 330.95 648.25 Td ( and ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 346.50 648.25 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 362.50 648.25 Td (.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 638.65 Td (\(c\) ) Tj ET Q q 0 0 0 rg BT 49.50 638.65 Td (Includes equity investments.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 613.3169921875 m 242.630859375 613.3169921875 l s q 0 0 0 rg BT 36.00 614.65 Td (Qualifying Hedges and Non-Qualifying Derivatives) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 597.65 Td (The following summarizes the fair value of outstanding derivatives:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 548.10 198.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 234.50 548.10 35.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 269.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 273.50 548.10 41.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 314.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 318.50 548.10 35.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 548.10 41.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 398.50 548.10 14.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 548.10 35.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 548.10 41.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 548.10 35.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 531.50 548.10 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 535.50 548.10 41.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 521.10 198.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 234.50 521.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 269.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 273.50 521.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 314.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 318.50 521.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 521.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 398.50 521.10 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 521.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 521.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 521.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 531.50 521.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 535.50 521.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 495.10 198.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 234.50 495.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 269.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 273.50 495.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 314.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 318.50 495.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 495.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 398.50 495.10 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 495.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 495.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 495.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 531.50 495.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 535.50 495.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 469.10 198.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 234.50 469.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 269.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 273.50 469.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 314.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 318.50 469.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 469.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 398.50 469.10 14.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 469.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 469.10 41.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 469.10 35.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 531.50 469.10 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 535.50 469.10 41.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 234.5 574.1 m 269.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 269.5 574.1 m 273.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 273.5 574.1 m 314.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 314.5 574.1 m 318.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 574.1 m 353.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 353.5 574.1 m 357.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 574.1 m 398.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 574.1 m 447.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 574.1 m 451.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 574.1 m 492.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 492.5 574.1 m 496.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 574.1 m 531.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 531.5 574.1 m 535.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 535.5 574.1 m 576.5 574.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 234.5 561.1 m 269.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 269.5 561.1 m 273.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 273.5 561.1 m 314.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 561.1 m 353.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 353.5 561.1 m 357.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 561.1 m 398.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 561.1 m 447.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 447.5 561.1 m 451.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 561.1 m 492.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 561.1 m 531.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 531.5 561.1 m 535.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 535.5 561.1 m 576.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 234.5 548.1 m 269.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 273.5 548.1 m 314.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 561.1 m 353.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 318.5 548.1 m 353.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 353.5 561.1 m 357.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 561.1 m 398.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 548.1 m 398.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 548.1 m 447.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 548.1 m 492.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 561.1 m 531.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 548.1 m 531.5 548.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 531.5 561.1 m 535.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 535.5 561.1 m 576.5 561.1 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 535.5 548.1 m 576.5 548.1 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 578.35 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 283.75 578.33 Td (December) Tj ET Q q 0 0 0 rg BT 318.32 578.33 Td ( 31, 2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 461.75 578.33 Td (December) Tj ET Q q 0 0 0 rg BT 496.25 578.33 Td ( 31, 2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 261.85 565.33 Td (Asset) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 280.07 568.96 Td (\(a\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 340.15 565.33 Td (Liability) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 369.49 568.96 Td (\(b\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 439.85 565.33 Td (Asset) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 458.07 568.96 Td (\(a\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 518.15 565.33 Td (Liability) Tj ET Q BT /F2 8.00 Tf ET BT /F2 5.20 Tf ET q 0 0 0 rg BT 547.49 568.96 Td (\(b\)) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 552.35 Td (Dollars in Millions) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 237.35 552.29 Td (Notional) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 276.30 552.29 Td (Fair) Tj ET Q q 0 0 0 rg BT 290.34 552.29 Td ( ) Tj ET Q q 0 0 0 rg BT 292.13 552.29 Td (V) Tj ET Q q 0 0 0 rg BT 297.27 552.29 Td (alue) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 321.35 552.29 Td (Notional) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 360.30 552.29 Td (Fair) Tj ET Q q 0 0 0 rg BT 374.34 552.29 Td ( ) Tj ET Q q 0 0 0 rg BT 376.13 552.29 Td (V) Tj ET Q q 0 0 0 rg BT 381.27 552.29 Td (alue) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 415.35 552.29 Td (Notional) Tj ET Q BT /F2 7.70 Tf ET q 0 0 0 rg BT 454.30 552.29 Td (Fair) Tj ET Q q 0 0 0 rg BT 468.34 552.29 Td ( ) Tj ET Q q 0 0 0 rg BT 470.13 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524.72 Td (\(6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 524.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.00 524.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.60 524.67 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 524.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 524.67 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 524.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.60 524.67 Td (755) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 538.00 524.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 524.67 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 524.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 511.67 Td (Forward starting interest rate swap contracts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 255.65 511.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.65 511.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.65 511.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.65 511.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.60 511.67 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 511.67 Td (8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.60 511.67 Td (250) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 511.67 Td (\(1) Tj ET Q q 0 0 0 rg BT 567.63 511.67 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 511.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 498.67 Td (Foreign currency forward contracts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 250.60 498.67 Td (944) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.65 498.67 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 334.60 498.67 Td (489) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 386.30 498.72 Td (\(9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 498.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.60 498.67 Td (967) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 498.67 Td (66) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.60 498.67 Td (198) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 498.67 Td (\(9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 498.67 Td (\)) Tj ET Q BT /F3 9.30 Tf ET q 0 0 0 rg BT 39.00 473.14 Td (Derivatives not designated as hedging instruments:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 459.67 Td (Foreign currency forward contracts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 250.60 459.67 Td (206) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 459.67 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.10 459.67 Td (1,369) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.30 459.72 Td (\(37) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.65 459.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.60 459.67 Td (106) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 459.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.60 459.67 Td (360) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 459.67 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 459.67 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 441.00 Td (\(a\) ) Tj ET Q q 0 0 0 rg BT 49.50 441.00 Td (Included ) Tj ET Q q 0 0 0 rg BT 79.49 441.00 Td (in ) Tj ET Q q 0 0 0 rg BT 87.71 441.00 Td (prepaid ) Tj ET Q q 0 0 0 rg BT 113.70 441.00 Td (expenses ) Tj ET Q q 0 0 0 rg BT 144.58 441.00 Td (and ) Tj ET Q q 0 0 0 rg BT 158.13 441.00 Td (other ) Tj ET Q q 0 0 0 rg BT 176.57 441.00 Td (and ) Tj ET Q q 0 0 0 rg BT 190.12 441.00 Td (other ) Tj ET Q q 0 0 0 rg BT 208.55 441.00 Td (assets.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 431.40 Td (\(b\) ) Tj ET Q q 0 0 0 rg BT 49.50 431.40 Td (Included ) Tj ET Q q 0 0 0 rg BT 79.49 431.40 Td (in ) Tj ET Q q 0 0 0 rg BT 87.71 431.40 Td (accrued ) Tj ET Q q 0 0 0 rg BT 114.58 431.40 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 146.35 431.40 Td (and ) Tj ET Q q 0 0 0 rg BT 159.90 431.40 Td (pension ) Tj ET Q q 0 0 0 rg BT 186.79 431.40 Td (and ) Tj ET Q q 0 0 0 rg BT 200.34 431.40 Td (other ) Tj ET Q q 0 0 0 rg BT 218.78 431.40 Td (liabilities.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 409.80 Td (Cash ) Tj ET Q q 0 0 0 rg BT 60.74 409.80 Td (Flow ) Tj ET Q q 0 0 0 rg BT 85.47 409.80 Td (Hedges ) Tj ET Q q 0 0 0 rg BT 119.64 409.80 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 128.53 409.80 Td ( ) Tj ET Q q 0 0 0 rg BT 132.71 409.80 Td (Foreign ) Tj ET Q q 0 0 0 rg BT 168.00 409.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 207.15 409.80 Td (forward ) Tj ET Q q 0 0 0 rg BT 242.98 409.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 283.25 409.80 Td (are ) Tj ET Q q 0 0 0 rg BT 299.64 409.80 Td (used ) Tj ET Q q 0 0 0 rg BT 322.15 409.80 Td (to ) Tj ET Q q 0 0 0 rg BT 334.10 409.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 362.16 409.80 Td (certain ) Tj ET Q q 0 0 0 rg BT 393.54 409.80 Td (forecasted ) Tj ET Q q 0 0 0 rg BT 438.80 409.80 Td (intercompany ) Tj ET Q q 0 0 0 rg BT 497.96 409.80 Td (inventory ) Tj ET Q q 0 0 0 rg BT 540.46 409.80 Td (purchase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 397.80 Td (transactions ) Tj ET Q q 0 0 0 rg BT 86.78 397.80 Td (and ) Tj ET Q q 0 0 0 rg BT 104.23 397.80 Td (certain ) Tj ET Q q 0 0 0 rg BT 134.44 397.80 Td (other ) Tj ET Q q 0 0 0 rg BT 158.00 397.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 189.89 397.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 227.88 397.80 Td (transactions. ) Tj ET Q q 0 0 0 rg BT 280.94 397.80 Td (The ) Tj ET Q q 0 0 0 rg BT 299.50 397.80 Td (ef) Tj ET Q q 0 0 0 rg BT 307.09 397.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 337.30 397.80 Td (portion ) Tj ET Q q 0 0 0 rg BT 369.20 397.80 Td (of ) Tj ET Q q 0 0 0 rg BT 380.54 397.80 Td (changes ) Tj ET Q q 0 0 0 rg BT 415.76 397.80 Td (in ) Tj ET Q q 0 0 0 rg BT 426.55 397.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 443.44 397.80 Td (value ) Tj ET Q q 0 0 0 rg BT 468.11 397.80 Td (for ) Tj ET Q q 0 0 0 rg BT 482.78 397.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 521.89 397.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 567.67 397.80 Td (as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 385.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 56.99 385.80 Td (flow ) Tj ET Q q 0 0 0 rg BT 78.54 385.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 109.53 385.80 Td (are ) Tj ET Q q 0 0 0 rg BT 124.96 385.80 Td (temporarily ) Tj ET Q q 0 0 0 rg BT 174.83 385.80 Td (reported ) Tj ET Q q 0 0 0 rg BT 211.36 385.80 Td (in ) Tj ET Q q 0 0 0 rg BT 222.36 385.80 Td (accumulated ) Tj ET Q q 0 0 0 rg BT 276.11 385.80 Td (other ) Tj ET Q q 0 0 0 rg BT 299.87 385.80 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 363.63 385.80 Td (loss ) Tj ET Q q 0 0 0 rg BT 382.41 385.80 Td (and ) Tj ET Q q 0 0 0 rg BT 400.07 385.80 Td (included ) Tj ET Q q 0 0 0 rg BT 437.72 385.80 Td (in ) Tj ET Q q 0 0 0 rg BT 448.72 385.80 Td (earnings ) Tj ET Q q 0 0 0 rg BT 485.82 385.80 Td (when ) Tj ET Q q 0 0 0 rg BT 510.70 385.80 Td (the ) Tj ET Q q 0 0 0 rg BT 526.13 385.80 Td (hedged ) Tj ET Q q 0 0 0 rg BT 558.23 385.80 Td (item ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 373.80 Td (af) Tj ET Q q 0 0 0 rg BT 43.59 373.80 Td (fects ) Tj ET Q q 0 0 0 rg BT 64.97 373.80 Td (earnings. ) Tj ET Q q 0 0 0 rg BT 103.67 373.80 Td (The ) Tj ET Q q 0 0 0 rg BT 121.72 373.80 Td (net ) Tj ET Q q 0 0 0 rg BT 136.43 373.80 Td (gains ) Tj ET Q q 0 0 0 rg BT 160.05 373.80 Td (on ) Tj ET Q q 0 0 0 rg BT 172.55 373.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 203.93 373.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 241.41 373.80 Td (forward ) Tj ET Q q 0 0 0 rg BT 275.56 373.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 314.15 373.80 Td (are ) Tj ET Q q 0 0 0 rg BT 328.86 373.80 Td (expected ) Tj ET Q q 0 0 0 rg BT 366.90 373.80 Td (to ) Tj ET Q q 0 0 0 rg BT 377.18 373.80 Td (be ) Tj ET Q q 0 0 0 rg BT 389.12 373.80 Td (reclassified ) Tj ET Q q 0 0 0 rg BT 437.15 373.80 Td (to ) Tj ET Q q 0 0 0 rg BT 447.44 373.80 Td (net ) Tj ET Q q 0 0 0 rg BT 462.15 373.80 Td (earnings ) Tj ET Q q 0 0 0 rg BT 498.53 373.80 Td (\(primarily ) Tj ET Q q 0 0 0 rg BT 541.58 373.80 Td (included ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 361.80 Td (in ) Tj ET Q q 0 0 0 rg BT 45.89 361.80 Td (cost ) Tj ET Q q 0 0 0 rg BT 64.11 361.80 Td (of ) Tj ET Q q 0 0 0 rg BT 74.55 361.80 Td (products ) Tj ET Q q 0 0 0 rg BT 111.10 361.80 Td (sold\) ) Tj ET Q q 0 0 0 rg BT 133.21 361.80 Td (within ) Tj ET Q q 0 0 0 rg BT 160.88 361.80 Td (the ) Tj ET Q q 0 0 0 rg BT 175.21 361.80 Td (next ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 194.54 361.80 Td (two) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 209.54 361.80 Td ( ) Tj ET Q q 0 0 0 rg BT 211.65 361.80 Td (years. ) Tj ET Q q 0 0 0 rg BT 237.21 361.80 Td (The ) Tj ET Q q 0 0 0 rg BT 254.87 361.80 Td (notional ) Tj ET Q q 0 0 0 rg BT 289.75 361.80 Td (amount ) Tj ET Q q 0 0 0 rg BT 321.86 361.80 Td (of ) Tj ET Q q 0 0 0 rg BT 332.30 361.80 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 381.08 361.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 412.07 361.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 449.16 361.80 Td (forward ) Tj ET Q q 0 0 0 rg BT 482.92 361.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 521.12 361.80 Td (was ) Tj ET Q q 0 0 0 rg BT 538.79 361.80 Td (primarily ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.80 Td (attributed ) Tj ET Q q 0 0 0 rg BT 76.82 349.80 Td (to ) Tj ET Q q 0 0 0 rg BT 87.10 349.80 Td (the ) Tj ET Q q 0 0 0 rg BT 101.82 349.80 Td (euro ) Tj ET Q q 0 0 0 rg BT 122.08 349.80 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 125.41 349.80 Td ($1,904 ) Tj ET Q q 0 0 0 rg BT 155.41 349.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 184.31 349.80 Td (\) ) Tj ET Q q 0 0 0 rg BT 190.14 349.80 Td (and ) Tj ET Q q 0 0 0 rg BT 207.07 349.80 Td (Japanese ) Tj ET Q q 0 0 0 rg BT 245.11 349.80 Td (yen ) Tj ET Q q 0 0 0 rg BT 262.05 349.80 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 265.38 349.80 Td ($31) Tj ET Q q 0 0 0 rg BT 280.01 349.80 Td (1 ) Tj ET Q q 0 0 0 rg BT 287.51 349.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 316.40 349.80 Td (\) ) Tj ET Q q 0 0 0 rg BT 322.23 349.80 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.95 349.80 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 390.53 349.80 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.53 349.80 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.80 Td (In ) Tj ET Q q 0 0 0 rg BT 46.63 325.80 Td (2015, ) Tj ET Q q 0 0 0 rg BT 71.42 325.80 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.84 325.80 Td (entered ) Tj ET Q q 0 0 0 rg BT 126.56 325.80 Td (into ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 144.41 325.80 Td ($750 ) Tj ET Q q 0 0 0 rg BT 166.70 325.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 195.59 325.80 Td ( ) Tj ET Q q 0 0 0 rg BT 197.89 325.80 Td (of ) Tj ET Q q 0 0 0 rg BT 208.51 325.80 Td (forward ) Tj ET Q q 0 0 0 rg BT 242.46 325.80 Td (starting ) Tj ET Q q 0 0 0 rg BT 274.75 325.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 306.48 325.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 323.76 325.80 Td (swap ) Tj ET Q q 0 0 0 rg BT 346.61 325.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 384.99 325.80 Td (maturing ) Tj ET Q q 0 0 0 rg BT 423.39 325.80 Td (in ) Tj ET Q q 0 0 0 rg BT 433.47 325.80 Td (March ) Tj ET Q q 0 0 0 rg BT 461.86 325.80 Td (2017 ) Tj ET Q q 0 0 0 rg BT 484.15 325.80 Td (to ) Tj ET Q q 0 0 0 rg BT 494.23 325.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 520.40 325.80 Td (the ) Tj ET Q q 0 0 0 rg BT 534.91 325.80 Td (variability ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 313.80 Td (of ) Tj ET Q q 0 0 0 rg BT 46.87 313.80 Td (probable ) Tj ET Q q 0 0 0 rg BT 84.40 313.80 Td (forecasted ) Tj ET Q q 0 0 0 rg BT 128.03 313.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 160.00 313.80 Td (expense ) Tj ET Q q 0 0 0 rg BT 194.75 313.80 Td (associated ) Tj ET Q q 0 0 0 rg BT 238.39 313.80 Td (with ) Tj ET Q q 0 0 0 rg BT 258.71 313.80 Td (potential ) Tj ET Q q 0 0 0 rg BT 296.25 313.80 Td (future ) Tj ET Q q 0 0 0 rg BT 322.67 313.80 Td (issuances ) Tj ET Q q 0 0 0 rg BT 362.98 313.80 Td (of ) Tj ET Q q 0 0 0 rg BT 373.85 313.80 Td (debt. ) Tj ET Q q 0 0 0 rg BT 396.11 313.80 Td (BMS ) Tj ET Q q 0 0 0 rg BT 419.78 313.80 Td (terminated ) Tj ET Q q 0 0 0 rg BT 465.08 313.80 Td (the ) Tj ET Q q 0 0 0 rg BT 479.84 313.80 Td (forward ) Tj ET Q q 0 0 0 rg BT 514.03 313.80 Td (starting ) Tj ET Q q 0 0 0 rg BT 546.57 313.80 Td (interest ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 301.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 53.19 301.80 Td (swap ) Tj ET Q q 0 0 0 rg BT 75.94 301.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 114.23 301.80 Td (in ) Tj ET Q q 0 0 0 rg BT 124.21 301.80 Td (2017 ) Tj ET Q q 0 0 0 rg BT 146.42 301.80 Td (and ) Tj ET Q q 0 0 0 rg BT 163.05 301.80 Td (the ) Tj ET Q q 0 0 0 rg BT 177.47 301.80 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 215.21 301.80 Td (and ) Tj ET Q q 0 0 0 rg BT 231.85 301.80 Td (related ) Tj ET Q q 0 0 0 rg BT 261.25 301.80 Td (gain ) Tj ET Q q 0 0 0 rg BT 280.67 301.80 Td (were ) Tj ET Q q 0 0 0 rg BT 302.30 301.80 Td (not ) Tj ET Q q 0 0 0 rg BT 317.28 301.80 Td (material. ) Tj ET Q q 0 0 0 rg BT 354.58 301.80 Td (The ) Tj ET Q q 0 0 0 rg BT 372.33 301.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 410.63 301.80 Td (were ) Tj ET Q q 0 0 0 rg BT 432.25 301.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 477.22 301.80 Td (as ) Tj ET Q q 0 0 0 rg BT 487.75 301.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 507.72 301.80 Td (flow ) Tj ET Q q 0 0 0 rg BT 528.25 301.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 558.22 301.80 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 289.80 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 289.80 Td (ef) Tj ET Q q 0 0 0 rg BT 58.30 289.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 88.01 289.80 Td (portion ) Tj ET Q q 0 0 0 rg BT 119.39 289.80 Td (of ) Tj ET Q q 0 0 0 rg BT 130.22 289.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 146.60 289.80 Td (value ) Tj ET Q q 0 0 0 rg BT 170.76 289.80 Td (changes ) Tj ET Q q 0 0 0 rg BT 205.46 289.80 Td (included ) Tj ET Q q 0 0 0 rg BT 242.40 289.80 Td (in ) Tj ET Q q 0 0 0 rg BT 252.67 289.80 Td (other ) Tj ET Q q 0 0 0 rg BT 275.72 289.80 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 338.75 289.80 Td (income.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 265.80 Td (The ) Tj ET Q q 0 0 0 rg BT 53.68 265.80 Td (earnings ) Tj ET Q q 0 0 0 rg BT 89.69 265.80 Td (impact ) Tj ET Q q 0 0 0 rg BT 119.04 265.80 Td (related ) Tj ET Q q 0 0 0 rg BT 148.37 265.80 Td (to ) Tj ET Q q 0 0 0 rg BT 158.29 265.80 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 211.52 265.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 231.42 265.80 Td (flow ) Tj ET Q q 0 0 0 rg BT 251.89 265.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 281.79 265.80 Td (and ) Tj ET Q q 0 0 0 rg BT 298.36 265.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 324.37 265.80 Td (inef) Tj ET Q q 0 0 0 rg BT 339.74 265.80 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 386.30 265.80 Td (was ) Tj ET Q q 0 0 0 rg BT 403.98 265.80 Td (not ) Tj ET Q q 0 0 0 rg BT 418.90 265.80 Td (significant ) Tj ET Q q 0 0 0 rg BT 463.24 265.80 Td (during ) Tj ET Q q 0 0 0 rg BT 491.48 265.80 Td (all ) Tj ET Q q 0 0 0 rg BT 503.61 265.80 Td (periods ) Tj ET Q q 0 0 0 rg BT 535.18 265.80 Td (presented. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 253.80 Td (Cash ) Tj ET Q q 0 0 0 rg BT 58.45 253.80 Td (flow ) Tj ET Q q 0 0 0 rg BT 79.24 253.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 105.56 253.80 Td (accounting ) Tj ET Q q 0 0 0 rg BT 151.89 253.80 Td (is ) Tj ET Q q 0 0 0 rg BT 161.01 253.80 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 214.57 253.80 Td (when ) Tj ET Q q 0 0 0 rg BT 238.68 253.80 Td (the ) Tj ET Q q 0 0 0 rg BT 253.35 253.80 Td (forecasted ) Tj ET Q q 0 0 0 rg BT 296.89 253.80 Td (transaction ) Tj ET Q q 0 0 0 rg BT 343.21 253.80 Td (is ) Tj ET Q q 0 0 0 rg BT 352.33 253.80 Td (no ) Tj ET Q q 0 0 0 rg BT 364.79 253.80 Td (longer ) Tj ET Q q 0 0 0 rg BT 392.79 253.80 Td (probable ) Tj ET Q q 0 0 0 rg BT 430.22 253.80 Td (of ) Tj ET Q q 0 0 0 rg BT 441.01 253.80 Td (occurring ) Tj ET Q q 0 0 0 rg BT 481.78 253.80 Td (within ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.78 253.80 Td (60) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.78 253.80 Td ( ) Tj ET Q q 0 0 0 rg BT 522.24 253.80 Td (days ) Tj ET Q q 0 0 0 rg BT 543.02 253.80 Td (after ) Tj ET Q q 0 0 0 rg BT 563.79 253.80 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 241.80 Td (originally ) Tj ET Q q 0 0 0 rg BT 76.61 241.80 Td (forecasted ) Tj ET Q q 0 0 0 rg BT 119.41 241.80 Td (date ) Tj ET Q q 0 0 0 rg BT 137.79 241.80 Td (or ) Tj ET Q q 0 0 0 rg BT 147.85 241.80 Td (when ) Tj ET Q q 0 0 0 rg BT 171.23 241.80 Td (the ) Tj ET Q q 0 0 0 rg BT 185.17 241.80 Td (hedge ) Tj ET Q q 0 0 0 rg BT 210.77 241.80 Td (is ) Tj ET Q q 0 0 0 rg BT 219.16 241.80 Td (no ) Tj ET Q q 0 0 0 rg BT 230.89 241.80 Td (longer ) Tj ET Q q 0 0 0 rg BT 258.16 241.80 Td (ef) Tj ET Q q 0 0 0 rg BT 265.75 241.80 Td (fective. ) Tj ET Q q 0 0 0 rg BT 296.79 241.80 Td (Assessments ) Tj ET Q q 0 0 0 rg BT 349.63 241.80 Td (to ) Tj ET Q q 0 0 0 rg BT 359.13 241.80 Td (determine ) Tj ET Q q 0 0 0 rg BT 400.83 241.80 Td (whether ) Tj ET Q q 0 0 0 rg BT 434.77 241.80 Td (derivatives ) Tj ET Q q 0 0 0 rg BT 480.36 241.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 524.85 241.80 Td (as ) Tj ET Q q 0 0 0 rg BT 534.90 241.80 Td (qualifying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 229.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 66.27 229.80 Td (are ) Tj ET Q q 0 0 0 rg BT 80.98 229.80 Td (highly ) Tj ET Q q 0 0 0 rg BT 109.03 229.80 Td (ef) Tj ET Q q 0 0 0 rg BT 116.62 229.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 146.32 229.80 Td (in ) Tj ET Q q 0 0 0 rg BT 156.60 229.80 Td (of) Tj ET Q q 0 0 0 rg BT 164.75 229.80 Td (fsetting ) Tj ET Q q 0 0 0 rg BT 197.25 229.80 Td (changes ) Tj ET Q q 0 0 0 rg BT 231.95 229.80 Td (in ) Tj ET Q q 0 0 0 rg BT 242.23 229.80 Td (the ) Tj ET Q q 0 0 0 rg BT 256.95 229.80 Td (cash ) Tj ET Q q 0 0 0 rg BT 277.22 229.80 Td (flows ) Tj ET Q q 0 0 0 rg BT 301.94 229.80 Td (of ) Tj ET Q q 0 0 0 rg BT 312.77 229.80 Td (hedged ) Tj ET Q q 0 0 0 rg BT 344.14 229.80 Td (items ) Tj ET Q q 0 0 0 rg BT 368.31 229.80 Td (are ) Tj ET Q q 0 0 0 rg BT 383.02 229.80 Td (performed ) Tj ET Q q 0 0 0 rg BT 427.16 229.80 Td (at ) Tj ET Q q 0 0 0 rg BT 436.88 229.80 Td (inception ) Tj ET Q q 0 0 0 rg BT 476.59 229.80 Td (and ) Tj ET Q q 0 0 0 rg BT 493.53 229.80 Td (on ) Tj ET Q q 0 0 0 rg BT 506.03 229.80 Td (a ) Tj ET Q q 0 0 0 rg BT 512.97 229.80 Td (quarterly ) Tj ET Q q 0 0 0 rg BT 551.56 229.80 Td (basis.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 205.80 Td (Net ) Tj ET Q q 0 0 0 rg BT 52.47 205.80 Td (Investment ) Tj ET Q q 0 0 0 rg BT 98.37 205.80 Td (Hedges ) Tj ET Q q 0 0 0 rg BT 130.95 205.80 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.84 205.80 Td ( ) Tj ET Q q 0 0 0 rg BT 142.42 205.80 Td (Non-U.S. ) Tj ET Q q 0 0 0 rg BT 183.34 205.80 Td (dollar ) Tj ET Q q 0 0 0 rg BT 209.25 205.80 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 257.39 205.80 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.30 205.80 Td (€950 ) Tj ET Q q 0 0 0 rg BT 290.89 205.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 319.78 205.80 Td ( ) Tj ET Q q 0 0 0 rg BT 322.36 205.80 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.69 205.80 Td ($1,127 ) Tj ET Q q 0 0 0 rg BT 355.78 205.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.67 205.80 Td (\) ) Tj ET Q q 0 0 0 rg BT 390.58 205.80 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.38 205.80 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 459.05 205.80 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.05 205.80 Td ( ) Tj ET Q q 0 0 0 rg BT 481.64 205.80 Td (are ) Tj ET Q q 0 0 0 rg BT 496.43 205.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 541.78 205.80 Td (to ) Tj ET Q q 0 0 0 rg BT 552.14 205.80 Td (hedge ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 193.80 Td (the ) Tj ET Q q 0 0 0 rg BT 51.41 193.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 83.49 193.80 Td (currency ) Tj ET Q q 0 0 0 rg BT 121.66 193.80 Td (exposures ) Tj ET Q q 0 0 0 rg BT 164.85 193.80 Td (of ) Tj ET Q q 0 0 0 rg BT 176.38 193.80 Td (the ) Tj ET Q q 0 0 0 rg BT 191.79 193.80 Td (net ) Tj ET Q q 0 0 0 rg BT 207.20 193.80 Td (investment ) Tj ET Q q 0 0 0 rg BT 254.28 193.80 Td (in ) Tj ET Q q 0 0 0 rg BT 265.26 193.80 Td (certain ) Tj ET Q q 0 0 0 rg BT 295.66 193.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 327.73 193.80 Td (af) Tj ET Q q 0 0 0 rg BT 335.32 193.80 Td (filiates. ) Tj ET Q q 0 0 0 rg BT 368.00 193.80 Td (These ) Tj ET Q q 0 0 0 rg BT 395.07 193.80 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 443.82 193.80 Td (are ) Tj ET Q q 0 0 0 rg BT 459.23 193.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 505.19 193.80 Td (as ) Tj ET Q q 0 0 0 rg BT 516.71 193.80 Td (net ) Tj ET Q q 0 0 0 rg BT 532.13 193.80 Td (investment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 181.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 66.56 181.80 Td (and ) Tj ET Q q 0 0 0 rg BT 83.79 181.80 Td (recognized ) Tj ET Q q 0 0 0 rg BT 130.45 181.80 Td (in ) Tj ET Q q 0 0 0 rg BT 141.02 181.80 Td (long ) Tj ET Q q 0 0 0 rg BT 161.59 181.80 Td (term ) Tj ET Q q 0 0 0 rg BT 182.70 181.80 Td (debt. ) Tj ET Q q 0 0 0 rg BT 205.01 181.80 Td (The ) Tj ET Q q 0 0 0 rg BT 223.35 181.80 Td (ef) Tj ET Q q 0 0 0 rg BT 230.94 181.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 260.93 181.80 Td (portion ) Tj ET Q q 0 0 0 rg BT 292.61 181.80 Td (of ) Tj ET Q q 0 0 0 rg BT 303.73 181.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 335.40 181.80 Td (exchange ) Tj ET Q q 0 0 0 rg BT 375.95 181.80 Td (loss ) Tj ET Q q 0 0 0 rg BT 394.30 181.80 Td (on ) Tj ET Q q 0 0 0 rg BT 407.09 181.80 Td (the ) Tj ET Q q 0 0 0 rg BT 422.10 181.80 Td (remeasurement ) Tj ET Q q 0 0 0 rg BT 485.97 181.80 Td (of ) Tj ET Q q 0 0 0 rg BT 497.09 181.80 Td (euro ) Tj ET Q q 0 0 0 rg BT 517.65 181.80 Td (debt ) Tj ET Q q 0 0 0 rg BT 537.66 181.80 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.01 181.80 Td ($134 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 169.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 169.80 Td ( ) Tj ET Q q 0 0 0 rg BT 67.79 169.80 Td (in ) Tj ET Q q 0 0 0 rg BT 78.46 169.80 Td (2017 ) Tj ET Q q 0 0 0 rg BT 101.36 169.80 Td (and ) Tj ET Q q 0 0 0 rg BT 118.70 169.80 Td (a ) Tj ET Q q 0 0 0 rg BT 126.03 169.80 Td (gain ) Tj ET Q q 0 0 0 rg BT 146.15 169.80 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.37 169.80 Td ($48 ) Tj ET Q q 0 0 0 rg BT 175.27 169.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 204.16 169.80 Td (, ) Tj ET Q q 0 0 0 rg BT 209.56 169.80 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 226.89 169.80 Td ($80 ) Tj ET Q q 0 0 0 rg BT 244.79 169.80 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 273.68 169.80 Td ( ) Tj ET Q q 0 0 0 rg BT 276.58 169.80 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 287.25 169.80 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.25 169.80 Td ( ) Tj ET Q q 0 0 0 rg BT 310.15 169.80 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.49 169.80 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.49 169.80 Td (, ) Tj ET Q q 0 0 0 rg BT 352.88 169.80 Td (respectively) Tj ET Q q 0 0 0 rg BT 400.54 169.80 Td (, ) Tj ET Q q 0 0 0 rg BT 405.94 169.80 Td (and ) Tj ET Q q 0 0 0 rg BT 423.28 169.80 Td (were ) Tj ET Q q 0 0 0 rg BT 445.60 169.80 Td (recorded ) Tj ET Q q 0 0 0 rg BT 483.48 169.80 Td (in ) Tj ET Q q 0 0 0 rg BT 494.15 169.80 Td (the ) Tj ET Q q 0 0 0 rg BT 509.26 169.80 Td (foreign ) Tj ET Q q 0 0 0 rg BT 541.04 169.80 Td (currency ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 157.80 Td (translation ) Tj ET Q q 0 0 0 rg BT 80.71 157.80 Td (component ) Tj ET Q q 0 0 0 rg BT 127.65 157.80 Td (of ) Tj ET Q q 0 0 0 rg BT 138.48 157.80 Td (accumulated ) Tj ET Q q 0 0 0 rg BT 191.50 157.80 Td (other ) Tj ET Q q 0 0 0 rg BT 214.55 157.80 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 277.58 157.80 Td (loss ) Tj ET Q q 0 0 0 rg BT 295.64 157.80 Td (with ) Tj ET Q q 0 0 0 rg BT 315.92 157.80 Td (the ) Tj ET Q q 0 0 0 rg BT 330.64 157.80 Td (related ) Tj ET Q q 0 0 0 rg BT 360.34 157.80 Td (of) Tj ET Q q 0 0 0 rg BT 368.49 157.80 Td (fset ) Tj ET Q q 0 0 0 rg BT 385.43 157.80 Td (in ) Tj ET Q q 0 0 0 rg BT 395.71 157.80 Td (long-term ) Tj ET Q q 0 0 0 rg BT 437.64 157.80 Td (debt.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 133.80 Td (Fair ) Tj ET Q q 0 0 0 rg BT 57.26 133.80 Td (V) Tj ET Q q 0 0 0 rg BT 62.26 133.80 Td (alue ) Tj ET Q q 0 0 0 rg BT 82.96 133.80 Td (Hedges ) Tj ET Q q 0 0 0 rg BT 116.43 133.80 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 125.32 133.80 Td ( ) Tj ET Q q 0 0 0 rg BT 128.80 133.80 Td (Fixed-to-floating ) Tj ET Q q 0 0 0 rg BT 200.60 133.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 233.52 133.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 251.99 133.80 Td (swap ) Tj ET Q q 0 0 0 rg BT 276.02 133.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 315.59 133.80 Td (are ) Tj ET Q q 0 0 0 rg BT 331.28 133.80 Td (designated ) Tj ET Q q 0 0 0 rg BT 377.53 133.80 Td (as ) Tj ET Q q 0 0 0 rg BT 389.34 133.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 406.70 133.80 Td (value ) Tj ET Q q 0 0 0 rg BT 431.83 133.80 Td (hedges ) Tj ET Q q 0 0 0 rg BT 463.08 133.80 Td (used ) Tj ET Q q 0 0 0 rg BT 484.90 133.80 Td (as ) Tj ET Q q 0 0 0 rg BT 496.71 133.80 Td (an ) Tj ET Q q 0 0 0 rg BT 509.63 133.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 542.54 133.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 561.01 133.80 Td (risk ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 121.80 Td (management ) Tj ET Q q 0 0 0 rg BT 89.68 121.80 Td (strategy ) Tj ET Q q 0 0 0 rg BT 123.92 121.80 Td (to ) Tj ET Q q 0 0 0 rg BT 134.29 121.80 Td (create ) Tj ET Q q 0 0 0 rg BT 160.75 121.80 Td (an ) Tj ET Q q 0 0 0 rg BT 172.77 121.80 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 220.90 121.80 Td (balance ) Tj ET Q q 0 0 0 rg BT 254.02 121.80 Td (of ) Tj ET Q q 0 0 0 rg BT 264.94 121.80 Td (fixed ) Tj ET Q q 0 0 0 rg BT 288.08 121.80 Td (and ) Tj ET Q q 0 0 0 rg BT 305.11 121.80 Td (floating ) Tj ET Q q 0 0 0 rg BT 338.80 121.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 356.38 121.80 Td (debt. ) Tj ET Q q 0 0 0 rg BT 378.50 121.80 Td (The ) Tj ET Q q 0 0 0 rg BT 396.63 121.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 435.32 121.80 Td (and ) Tj ET Q q 0 0 0 rg BT 452.35 121.80 Td (underlying ) Tj ET Q q 0 0 0 rg BT 498.26 121.80 Td (debt ) Tj ET Q q 0 0 0 rg BT 518.07 121.80 Td (for ) Tj ET Q q 0 0 0 rg BT 532.32 121.80 Td (the ) Tj ET Q q 0 0 0 rg BT 547.13 121.80 Td (hedged ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 109.80 Td (benchmark ) Tj ET Q q 0 0 0 rg BT 83.01 109.80 Td (risk ) Tj ET Q q 0 0 0 rg BT 100.59 109.80 Td (are ) Tj ET Q q 0 0 0 rg BT 115.39 109.80 Td (recorded ) Tj ET Q q 0 0 0 rg BT 152.95 109.80 Td (at ) Tj ET Q q 0 0 0 rg BT 162.75 109.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 179.21 109.80 Td (value. ) Tj ET Q q 0 0 0 rg BT 205.77 109.80 Td (The ) Tj ET Q q 0 0 0 rg BT 223.90 109.80 Td (ef) Tj ET Q q 0 0 0 rg BT 231.49 109.80 Td (fective ) Tj ET Q q 0 0 0 rg BT 261.27 109.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 293.29 109.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 310.86 109.80 Td (for ) Tj ET Q q 0 0 0 rg BT 325.11 109.80 Td (the ) Tj ET Q q 0 0 0 rg BT 339.91 109.80 Td (contracts ) Tj ET Q q 0 0 0 rg BT 378.59 109.80 Td (is ) Tj ET Q q 0 0 0 rg BT 387.85 109.80 Td (one-month ) Tj ET Q q 0 0 0 rg BT 433.76 109.80 Td (LIBOR ) Tj ET Q q 0 0 0 rg BT 466.34 109.80 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.67 109.80 Td (1.56%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 495.50 109.80 Td ( ) Tj ET Q q 0 0 0 rg BT 498.09 109.80 Td (as ) Tj ET Q q 0 0 0 rg BT 509.00 109.80 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.92 109.80 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 97.80 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 56.00 97.80 Td (\) ) Tj ET Q q 0 0 0 rg BT 61.98 97.80 Td (plus ) Tj ET Q q 0 0 0 rg BT 81.29 97.80 Td (an ) Tj ET Q q 0 0 0 rg BT 93.38 97.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 125.46 97.80 Td (rate ) Tj ET Q q 0 0 0 rg BT 143.09 97.80 Td (spread ) Tj ET Q q 0 0 0 rg BT 171.83 97.80 Td (ranging ) Tj ET Q q 0 0 0 rg BT 205.03 97.80 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 227.11 97.80 Td (0.3%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 247.94 97.80 Td ( ) Tj ET Q q 0 0 0 rg BT 250.59 97.80 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 261.01 97.80 Td (4.6%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 281.84 97.80 Td (. ) Tj ET Q q 0 0 0 rg BT 286.80 97.80 Td (When ) Tj ET Q q 0 0 0 rg BT 313.32 97.80 Td (the ) Tj ET Q q 0 0 0 rg BT 328.19 97.80 Td (underlying ) Tj ET Q q 0 0 0 rg BT 374.16 97.80 Td (swap ) Tj ET Q q 0 0 0 rg BT 397.36 97.80 Td (is ) Tj ET Q q 0 0 0 rg BT 406.67 97.80 Td (terminated ) Tj ET Q q 0 0 0 rg BT 452.08 97.80 Td (prior ) Tj ET Q q 0 0 0 rg BT 474.16 97.80 Td (to ) Tj ET Q q 0 0 0 rg BT 484.59 97.80 Td (maturity) Tj ET Q q 0 0 0 rg BT 517.82 97.80 Td (, ) Tj ET Q q 0 0 0 rg BT 522.97 97.80 Td (the ) Tj ET Q q 0 0 0 rg BT 537.83 97.80 Td (fair ) Tj ET Q q 0 0 0 rg BT 554.35 97.80 Td (value ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 85.80 Td (basis ) Tj ET Q q 0 0 0 rg BT 58.50 85.80 Td (adjustment ) Tj ET Q q 0 0 0 rg BT 104.88 85.80 Td (to ) Tj ET Q q 0 0 0 rg BT 115.16 85.80 Td (the ) Tj ET Q q 0 0 0 rg BT 129.88 85.80 Td (underlying ) Tj ET Q q 0 0 0 rg BT 175.70 85.80 Td (debt ) Tj ET Q q 0 0 0 rg BT 195.42 85.80 Td (instrument ) Tj ET Q q 0 0 0 rg BT 240.69 85.80 Td (is ) Tj ET Q q 0 0 0 rg BT 249.86 85.80 Td (amortized ) Tj ET Q q 0 0 0 rg BT 292.34 85.80 Td (as ) Tj ET Q q 0 0 0 rg BT 303.17 85.80 Td (a ) Tj ET Q q 0 0 0 rg BT 310.11 85.80 Td (reduction ) Tj ET Q q 0 0 0 rg BT 350.38 85.80 Td (to ) Tj ET Q q 0 0 0 rg BT 360.65 85.80 Td (interest ) Tj ET Q q 0 0 0 rg BT 392.59 85.80 Td (expense ) Tj ET Q q 0 0 0 rg BT 427.29 85.80 Td (over ) Tj ET Q q 0 0 0 rg BT 447.56 85.80 Td (the ) Tj ET Q q 0 0 0 rg BT 462.28 85.80 Td (remaining ) Tj ET Q q 0 0 0 rg BT 505.32 85.80 Td (life ) Tj ET Q q 0 0 0 rg BT 521.15 85.80 Td (of ) Tj ET Q q 0 0 0 rg BT 531.98 85.80 Td (the ) Tj ET Q q 0 0 0 rg BT 546.69 85.80 Td (debt.) Tj ET Q endstream endobj 175 0 obj <> endobj 176 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 53.95 749.10 Td (notional ) Tj ET Q q 0 0 0 rg BT 89.12 749.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 121.52 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 132.25 749.10 Td (fixed-to-floating ) Tj ET Q q 0 0 0 rg BT 200.73 749.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 232.57 749.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 249.95 749.10 Td (swap ) Tj ET Q q 0 0 0 rg BT 272.90 749.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 311.40 749.10 Td (executed ) Tj ET Q q 0 0 0 rg BT 349.33 749.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.28 749.10 Td ($255 ) Tj ET Q q 0 0 0 rg BT 389.68 749.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.57 749.10 Td ( ) Tj ET Q q 0 0 0 rg BT 420.97 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 431.15 749.10 Td (2016. ) Tj ET Q q 0 0 0 rg BT 455.88 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 473.82 749.10 Td (notional ) Tj ET Q q 0 0 0 rg BT 509.00 749.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 541.39 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 552.12 749.10 Td (fixed-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (to-floating ) Tj ET Q q 0 0 0 rg BT 80.25 737.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 111.71 737.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 128.73 737.10 Td (swap ) Tj ET Q q 0 0 0 rg BT 151.32 737.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 189.44 737.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 234.24 737.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.82 737.10 Td ($500 ) Tj ET Q q 0 0 0 rg BT 273.86 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.75 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 304.78 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 314.59 737.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 336.63 737.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.10 737.10 Td ($147 ) Tj ET Q q 0 0 0 rg BT 375.13 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.02 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 406.06 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 415.87 737.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 437.90 737.10 Td (generating ) Tj ET Q q 0 0 0 rg BT 482.14 737.10 Td (proceeds ) Tj ET Q q 0 0 0 rg BT 519.71 737.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 530.07 737.10 Td ($43 ) Tj ET Q q 0 0 0 rg BT 547.11 737.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.11 725.10 Td (2016 ) Tj ET Q q 0 0 0 rg BT 68.45 725.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.23 725.10 Td ($28 ) Tj ET Q q 0 0 0 rg BT 102.56 725.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 131.45 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 133.79 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 143.91 725.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 166.24 725.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 209.68 725.10 Td (accrued ) Tj ET Q q 0 0 0 rg BT 243.10 725.10 Td (interest\). ) Tj ET Q q 0 0 0 rg BT 280.19 725.10 Td (Additional ) Tj ET Q q 0 0 0 rg BT 325.30 725.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 363.73 725.10 Td (were ) Tj ET Q q 0 0 0 rg BT 385.49 725.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 430.59 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 440.70 725.10 Td (connection ) Tj ET Q q 0 0 0 rg BT 486.91 725.10 Td (with ) Tj ET Q q 0 0 0 rg BT 507.02 725.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 526.58 725.10 Td (redemptions ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 713.10 Td (2015.) Tj ET Q BT /F3 10.00 Tf ET 0 0 0 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 36 687.7669921875 m 105.1650390625 687.7669921875 l s q 0 0 0 rg BT 36.00 689.10 Td (Debt Obligations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 667.50 Td (Short-term ) Tj ET Q q 0 0 0 rg BT 81.83 667.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 101.54 667.50 Td (obligations ) Tj ET Q q 0 0 0 rg BT 148.49 667.50 Td (include:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 629.00 376.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 629.00 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 629.00 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 629.00 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 599.00 376.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 599.00 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 599.00 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 599.00 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 569.00 376.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 411.50 569.00 80.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 569.00 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 569.00 80.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 644 m 491.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 491.5 644 m 495.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 644 m 575.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 644 m 491.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 629 m 491.5 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 491.5 644 m 495.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 644 m 575.5 644 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 629 m 575.5 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 629 m 491.5 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 629 m 575.5 629 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 569 m 491.5 569 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 569 m 575.5 569 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 555 m 491.5 555 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 411.5 553 m 491.5 553 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 555 m 575.5 555 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 553 m 575.5 553 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 469.75 648.23 Td (December) Tj ET Q q 0 0 0 rg BT 504.32 648.23 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 633.25 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 443.00 633.23 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 527.00 633.23 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 619.57 Td (Commercial paper) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.00 618.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 618.67 Td (299) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 618.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 618.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 604.57 Td (Non-U.S. short-term borrowings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 603.67 Td (512) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 603.67 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 589.57 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 588.67 Td (176) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 588.67 Td (134) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 574.57 Td (Current portion of long-term debt) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 573.67 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 573.67 Td (749) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 559.57 Td (T) Tj ET Q q 0 0 0 rg BT 43.41 559.57 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.00 558.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 558.67 Td (987) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 558.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 558.67 Td (992) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 530.50 Td (The ) Tj ET Q q 0 0 0 rg BT 54.14 530.50 Td (average ) Tj ET Q q 0 0 0 rg BT 87.82 530.50 Td (amount ) Tj ET Q q 0 0 0 rg BT 120.40 530.50 Td (of ) Tj ET Q q 0 0 0 rg BT 131.33 530.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 181.12 530.50 Td (paper ) Tj ET Q q 0 0 0 rg BT 205.92 530.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 255.17 530.50 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 273.32 530.50 Td ($389 ) Tj ET Q q 0 0 0 rg BT 295.91 530.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 324.80 530.50 Td ( ) Tj ET Q q 0 0 0 rg BT 327.40 530.50 Td (at ) Tj ET Q q 0 0 0 rg BT 337.21 530.50 Td (a ) Tj ET Q q 0 0 0 rg BT 344.24 530.50 Td (weighted-average ) Tj ET Q q 0 0 0 rg BT 417.90 530.50 Td (interest ) Tj ET Q q 0 0 0 rg BT 449.93 530.50 Td (rate ) Tj ET Q q 0 0 0 rg BT 467.50 530.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.43 530.50 Td (1.17%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.26 530.50 Td ( ) Tj ET Q q 0 0 0 rg BT 506.85 530.50 Td (during ) Tj ET Q q 0 0 0 rg BT 535.55 530.50 Td (2017. ) Tj ET Q q 0 0 0 rg BT 560.46 530.50 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 518.50 Td (maximum ) Tj ET Q q 0 0 0 rg BT 79.13 518.50 Td (amount ) Tj ET Q q 0 0 0 rg BT 111.70 518.50 Td (of ) Tj ET Q q 0 0 0 rg BT 122.60 518.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 172.38 518.50 Td (paper ) Tj ET Q q 0 0 0 rg BT 197.16 518.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 246.40 518.50 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.53 518.50 Td ($1.3 ) Tj ET Q q 0 0 0 rg BT 284.60 518.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.72 518.50 Td ( ) Tj ET Q q 0 0 0 rg BT 313.29 518.50 Td (with ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.65 518.50 Td ($299 ) Tj ET Q q 0 0 0 rg BT 356.22 518.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 385.11 518.50 Td ( ) Tj ET Q q 0 0 0 rg BT 387.69 518.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 436.93 518.50 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 485.06 518.50 Td (at ) Tj ET Q q 0 0 0 rg BT 494.85 518.50 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 553.51 518.50 Td (2017. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 506.50 Td (There ) Tj ET Q q 0 0 0 rg BT 61.82 506.50 Td (were ) Tj ET Q q 0 0 0 rg BT 83.74 506.50 Td (no ) Tj ET Q q 0 0 0 rg BT 96.24 506.50 Td (commercial ) Tj ET Q q 0 0 0 rg BT 145.94 506.50 Td (paper ) Tj ET Q q 0 0 0 rg BT 170.65 506.50 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 218.70 506.50 Td (in ) Tj ET Q q 0 0 0 rg BT 228.98 506.50 Td (2016. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 482.50 Td (Long-term debt and the current portion of long-term debt includes:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 448.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 448.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 448.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 448.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 448.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 424.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 424.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 424.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 424.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 424.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 400.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 400.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 400.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 400.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 400.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 376.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 376.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 376.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 376.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 376.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 352.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 352.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 352.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 352.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 352.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 328.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 328.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 328.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 328.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 328.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 304.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 304.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 304.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 304.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 304.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 280.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 280.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 280.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 280.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 280.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 256.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 256.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 256.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 256.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 256.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 232.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 232.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 232.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 232.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 232.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 208.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 208.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 208.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 208.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 208.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 184.00 372.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 184.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 184.00 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 184.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 184.00 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 156.00 372.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 156.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 156.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 156.00 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 156.00 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 131.00 372.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 131.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 131.00 80.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 131.00 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 131.00 80.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 460 m 492.5 460 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 492.5 460 m 496.5 460 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 460 m 576.5 460 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 448 m 492.5 448 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 448 m 576.5 448 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 244 m 492.5 244 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 244 m 576.5 244 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 232 m 492.5 232 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 232 m 576.5 232 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 171 m 492.5 171 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 171 m 576.5 171 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 157 m 492.5 157 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 412.5 155 m 492.5 155 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 157 m 576.5 157 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 155 m 576.5 155 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 463.95 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 470.75 464.08 Td (December) Tj ET Q q 0 0 0 rg BT 505.32 464.08 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 451.95 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.00 452.08 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.00 452.08 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 438.62 Td (Principal ) Tj ET Q q 0 0 0 rg BT 77.51 438.62 Td (V) Tj ET Q q 0 0 0 rg BT 84.09 438.62 Td (alue:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 426.62 Td (0.875% Notes due 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.00 426.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 426.62 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 426.62 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 426.62 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 414.62 Td (1.750% Notes due 2019) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 414.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 414.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 402.62 Td (1.600% Notes due 2019) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 402.62 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 402.62 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 390.62 Td (2.000% Notes due 2022) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 390.62 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 390.62 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 378.62 Td (7.150% Notes due 2023) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 378.62 Td (302) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 378.62 Td (302) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 366.62 Td (3.250% Notes due 2023) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 366.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 366.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 354.62 Td (1.000% Euro Notes due 2025) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 354.62 Td (682) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 354.62 Td (601) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 342.62 Td (6.800% Notes due 2026) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 342.62 Td (256) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 342.62 Td (256) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 330.62 Td (3.250% Notes due 2027) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 330.62 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 330.62 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 318.62 Td (1.750% Euro Notes due 2035) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 318.62 Td (682) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 318.62 Td (601) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 306.62 Td (5.875% Notes due 2036) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 306.62 Td (287) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 306.62 Td (404) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 294.62 Td (6.125% Notes due 2038) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 294.62 Td (230) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 294.62 Td (278) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 282.62 Td (3.250% Notes due 2042) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 282.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 282.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 270.62 Td (4.500% Notes due 2044) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 270.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 270.62 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 258.62 Td (6.875% Notes due 2097) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 258.62 Td (87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 258.62 Td (260) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 246.62 Td (0% - 5.75% Other - maturing 2018 - 2024) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 246.62 Td (59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 246.62 Td (59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 234.62 Td (Subtotal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 234.62 Td (6,835) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 234.62 Td (6,261) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 210.62 Td (Adjustments to Principal ) Tj ET Q q 0 0 0 rg BT 140.85 210.62 Td (V) Tj ET Q q 0 0 0 rg BT 147.43 210.62 Td (alue:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 198.62 Td (Fair value of interest rate swap contracts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.30 198.62 Td (\(6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 198.62 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 198.62 Td (\(2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 198.62 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 186.62 Td (Unamortized basis adjustment from swap terminations) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 186.62 Td (227) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 186.62 Td (287) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 174.57 Td (Unamortized bond discounts and issuance costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 174.62 Td (\(81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 174.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 174.57 Td (\(81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 174.57 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 161.57 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 161.57 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.00 160.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 160.67 Td (6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 160.67 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 160.67 Td (6,465) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 134.57 Td (Current portion of long-term debt) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.00 134.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 134.57 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 134.57 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 134.57 Td (749) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 121.57 Td (Long-term debt) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 121.57 Td (6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 121.57 Td (5,716) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 94.50 Td (The ) Tj ET Q q 0 0 0 rg BT 53.75 94.50 Td (fair ) Tj ET Q q 0 0 0 rg BT 69.84 94.50 Td (value ) Tj ET Q q 0 0 0 rg BT 93.70 94.50 Td (of ) Tj ET Q q 0 0 0 rg BT 104.24 94.50 Td (long-term ) Tj ET Q q 0 0 0 rg BT 145.88 94.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 165.30 94.50 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 183.06 94.50 Td ($7.5 ) Tj ET Q q 0 0 0 rg BT 202.77 94.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 228.88 94.50 Td ( ) Tj ET Q q 0 0 0 rg BT 231.09 94.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 247.73 94.50 Td ($6.9 ) Tj ET Q q 0 0 0 rg BT 267.44 94.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 293.55 94.50 Td ( ) Tj ET Q q 0 0 0 rg BT 295.76 94.50 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.18 94.50 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 363.48 94.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.48 94.50 Td ( ) Tj ET Q q 0 0 0 rg BT 385.68 94.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 402.33 94.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.33 94.50 Td (, ) Tj ET Q q 0 0 0 rg BT 427.04 94.50 Td (respectively) Tj ET Q q 0 0 0 rg BT 474.70 94.50 Td (, ) Tj ET Q q 0 0 0 rg BT 479.40 94.50 Td (and ) Tj ET Q q 0 0 0 rg BT 496.05 94.50 Td (was ) Tj ET Q q 0 0 0 rg BT 513.81 94.50 Td (estimated ) Tj ET Q q 0 0 0 rg BT 554.33 94.50 Td (using ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 82.50 Td (Level ) Tj ET Q q 0 0 0 rg BT 61.93 82.50 Td (2 ) Tj ET Q q 0 0 0 rg BT 70.09 82.50 Td (inputs ) Tj ET Q q 0 0 0 rg BT 97.70 82.50 Td (which ) Tj ET Q q 0 0 0 rg BT 125.30 82.50 Td (are ) Tj ET Q q 0 0 0 rg BT 140.67 82.50 Td (based ) Tj ET Q q 0 0 0 rg BT 166.60 82.50 Td (upon ) Tj ET Q q 0 0 0 rg BT 189.76 82.50 Td (the ) Tj ET Q q 0 0 0 rg BT 205.14 82.50 Td (quoted ) Tj ET Q q 0 0 0 rg BT 235.51 82.50 Td (market ) Tj ET Q q 0 0 0 rg BT 266.44 82.50 Td (prices ) Tj ET Q q 0 0 0 rg BT 293.48 82.50 Td (for ) Tj ET Q q 0 0 0 rg BT 308.30 82.50 Td (the ) Tj ET Q q 0 0 0 rg BT 323.68 82.50 Td (same ) Tj ET Q q 0 0 0 rg BT 347.39 82.50 Td (or ) Tj ET Q q 0 0 0 rg BT 358.88 82.50 Td (similar ) Tj ET Q q 0 0 0 rg BT 389.81 82.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 410.19 82.50 Td (instruments. ) Tj ET Q q 0 0 0 rg BT 462.29 82.50 Td (The ) Tj ET Q q 0 0 0 rg BT 481.00 82.50 Td (fair ) Tj ET Q q 0 0 0 rg BT 498.04 82.50 Td (value ) Tj ET Q q 0 0 0 rg BT 522.85 82.50 Td (of ) Tj ET Q q 0 0 0 rg BT 534.35 82.50 Td (short-term ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 70.50 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 84.05 70.50 Td (approximates ) Tj ET Q q 0 0 0 rg BT 140.42 70.50 Td (the ) Tj ET Q q 0 0 0 rg BT 155.14 70.50 Td (carrying ) Tj ET Q q 0 0 0 rg BT 190.96 70.50 Td (value ) Tj ET Q q 0 0 0 rg BT 215.11 70.50 Td (due ) Tj ET Q q 0 0 0 rg BT 232.05 70.50 Td (to ) Tj ET Q q 0 0 0 rg BT 242.33 70.50 Td (the ) Tj ET Q q 0 0 0 rg BT 257.04 70.50 Td (short ) Tj ET Q q 0 0 0 rg BT 279.54 70.50 Td (maturities ) Tj ET Q q 0 0 0 rg BT 322.04 70.50 Td (of ) Tj ET Q q 0 0 0 rg BT 332.87 70.50 Td (the ) Tj ET Q q 0 0 0 rg BT 347.58 70.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 367.30 70.50 Td (instruments.) Tj ET Q endstream endobj 177 0 obj <> endobj 178 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (88) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (Senior ) Tj ET Q q 0 0 0 rg BT 64.57 749.10 Td (unsecured ) Tj ET Q q 0 0 0 rg BT 107.57 749.10 Td (notes ) Tj ET Q q 0 0 0 rg BT 131.13 749.10 Td (were ) Tj ET Q q 0 0 0 rg BT 153.02 749.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 180.48 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 190.72 749.10 Td (registered ) Tj ET Q q 0 0 0 rg BT 232.60 749.10 Td (public ) Tj ET Q q 0 0 0 rg BT 260.06 749.10 Td (of) Tj ET Q q 0 0 0 rg BT 268.21 749.10 Td (ferings ) Tj ET Q q 0 0 0 rg BT 298.44 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 308.68 749.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 331.14 749.10 Td (and ) Tj ET Q q 0 0 0 rg BT 348.03 749.10 Td (2015. ) Tj ET Q q 0 0 0 rg BT 372.82 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 390.82 749.10 Td (notes ) Tj ET Q q 0 0 0 rg BT 414.39 749.10 Td (rank ) Tj ET Q q 0 0 0 rg BT 434.62 749.10 Td (equally ) Tj ET Q q 0 0 0 rg BT 466.51 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 476.75 749.10 Td (right ) Tj ET Q q 0 0 0 rg BT 498.10 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 508.89 749.10 Td (payment ) Tj ET Q q 0 0 0 rg BT 545.78 749.10 Td (with ) Tj ET Q q 0 0 0 rg BT 566.02 749.10 Td (all ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 47.68 737.10 Td (BMS's ) Tj ET Q q 0 0 0 rg BT 77.84 737.10 Td (existing ) Tj ET Q q 0 0 0 rg BT 112.86 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 130.64 737.10 Td (future ) Tj ET Q q 0 0 0 rg BT 157.87 737.10 Td (senior ) Tj ET Q q 0 0 0 rg BT 185.66 737.10 Td (unsecured ) Tj ET Q q 0 0 0 rg BT 229.54 737.10 Td (indebtedness ) Tj ET Q q 0 0 0 rg BT 284.55 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 302.33 737.10 Td (are ) Tj ET Q q 0 0 0 rg BT 317.89 737.10 Td (redeemable ) Tj ET Q q 0 0 0 rg BT 367.32 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 378.44 737.10 Td (whole ) Tj ET Q q 0 0 0 rg BT 406.23 737.10 Td (or ) Tj ET Q q 0 0 0 rg BT 417.91 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 429.04 737.10 Td (part, ) Tj ET Q q 0 0 0 rg BT 450.43 737.10 Td (at ) Tj ET Q q 0 0 0 rg BT 461.00 737.10 Td (any ) Tj ET Q q 0 0 0 rg BT 478.79 737.10 Td (time ) Tj ET Q q 0 0 0 rg BT 499.91 737.10 Td (at ) Tj ET Q q 0 0 0 rg BT 510.47 737.10 Td (a ) Tj ET Q q 0 0 0 rg BT 518.26 737.10 Td (predetermined ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (redemption ) Tj ET Q q 0 0 0 rg BT 83.87 725.10 Td (price. ) Tj ET Q q 0 0 0 rg BT 108.68 725.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 132.12 725.10 Td (also ) Tj ET Q q 0 0 0 rg BT 150.56 725.10 Td (terminated ) Tj ET Q q 0 0 0 rg BT 195.64 725.10 Td (forward ) Tj ET Q q 0 0 0 rg BT 229.61 725.10 Td (starting ) Tj ET Q q 0 0 0 rg BT 261.93 725.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 293.69 725.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 311.00 725.10 Td (swap ) Tj ET Q q 0 0 0 rg BT 333.88 725.10 Td (contracts ) Tj ET Q q 0 0 0 rg BT 372.29 725.10 Td (entered ) Tj ET Q q 0 0 0 rg BT 404.04 725.10 Td (into ) Tj ET Q q 0 0 0 rg BT 421.92 725.10 Td (during ) Tj ET Q q 0 0 0 rg BT 450.36 725.10 Td (2015, ) Tj ET Q q 0 0 0 rg BT 475.18 725.10 Td (resulting ) Tj ET Q q 0 0 0 rg BT 512.50 725.10 Td (in ) Tj ET Q q 0 0 0 rg BT 522.60 725.10 Td (an ) Tj ET Q q 0 0 0 rg BT 534.36 725.10 Td (unrealized ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 53.76 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 63.73 713.10 Td (other ) Tj ET Q q 0 0 0 rg BT 86.47 713.10 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 149.19 713.10 Td (income. ) Tj ET Q q 0 0 0 rg BT 183.16 713.10 Td (The ) Tj ET Q q 0 0 0 rg BT 200.90 713.10 Td (following ) Tj ET Q q 0 0 0 rg BT 241.98 713.10 Td (table ) Tj ET Q q 0 0 0 rg BT 263.61 713.10 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 313.57 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 327.98 713.10 Td (issuance ) Tj ET Q q 0 0 0 rg BT 364.05 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 374.57 713.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 416.20 713.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 435.61 713.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 482.25 713.10 Td (in ) Tj ET Q q 0 0 0 rg BT 492.22 713.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 514.42 713.10 Td (and ) Tj ET Q q 0 0 0 rg BT 531.05 713.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 553.24 713.10 Td (\(none ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 701.10 Td (2016\):) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 660.60 396.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 660.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 660.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 660.60 44.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 660.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 660.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 630.60 396.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 630.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 630.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 630.60 44.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 630.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 630.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 600.60 396.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 600.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 600.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 600.60 44.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 600.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 600.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 570.60 396.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 570.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 570.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 570.60 44.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 570.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 570.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 542.60 396.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 542.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 542.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 542.60 44.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 542.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 542.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 514.60 396.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 514.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 514.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 514.60 44.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 514.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 514.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 484.60 396.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 432.50 484.60 46.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 478.50 484.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 482.50 484.60 44.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 484.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 484.60 46.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 675.6 m 478.5 675.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 482.5 675.6 m 526.5 675.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 526.5 675.6 m 530.5 675.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 675.6 m 576.5 675.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 660.6 m 478.5 660.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 482.5 660.6 m 526.5 660.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 660.6 m 576.5 660.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 585.6 m 478.5 585.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 571.6 m 478.5 571.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 432.5 569.6 m 478.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 482.5 585.6 m 526.5 585.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 482.5 571.6 m 526.5 571.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 482.5 569.6 m 526.5 569.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 585.6 m 576.5 585.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 571.6 m 576.5 571.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 569.6 m 576.5 569.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 447.00 679.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 521.00 679.83 Td (2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 664.85 Td (Amounts in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 435.10 664.83 Td (U.S. dollars) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 495.40 664.83 Td (Eur) Tj ET Q q 0 0 0 rg BT 508.66 664.83 Td (o) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.10 664.83 Td (U.S. dollars) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 650.27 Td (Principal ) Tj ET Q q 0 0 0 rg BT 77.51 650.27 Td (V) Tj ET Q q 0 0 0 rg BT 84.09 650.27 Td (alue:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 635.27 Td (1.600% Notes due 2019) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 635.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.65 635.27 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.00 635.27 Td (€) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 635.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 635.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 635.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 620.27 Td (1.000% Euro Notes due 2025) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.65 620.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 620.27 Td (575) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 620.27 Td (643) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 605.27 Td (3.250% Notes due 2027) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.65 605.27 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 605.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 605.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 590.27 Td (1.750% Euro Notes due 2035) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.65 590.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 590.27 Td (575) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 590.27 Td (643) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 575.27 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 575.27 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 575.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 575.27 Td (1,500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.00 575.27 Td (€) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 575.27 Td (1,150) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 575.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 575.27 Td (1,286) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 547.27 Td (Proceeds net of discount and deferred loan issuance costs) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 547.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 547.27 Td (1,488) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.00 547.27 Td (€) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 547.27 Td (1,133) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 547.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 547.27 Td (1,268) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 519.27 Td (Forward starting interest rate swap contracts terminated:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 504.27 Td (Notional amount) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.00 504.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.65 504.27 Td (750) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.00 504.27 Td (€) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 504.27 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 504.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 504.27 Td (559) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 489.27 Td (Realized gain) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.65 489.27 Td (6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 489.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 489.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 474.27 Td (Unrealized loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.30 474.32 Td (\(2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 474.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.30 474.32 Td (\(16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 474.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 474.27 Td (\(18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 474.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 446.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 60.03 446.10 Td (repaid ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.92 446.10 Td ($750 ) Tj ET Q q 0 0 0 rg BT 110.82 446.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 139.71 446.10 Td ( ) Tj ET Q q 0 0 0 rg BT 142.62 446.10 Td (of ) Tj ET Q q 0 0 0 rg BT 153.85 446.10 Td (0.875% ) Tj ET Q q 0 0 0 rg BT 187.59 446.10 Td (Notes ) Tj ET Q q 0 0 0 rg BT 213.82 446.10 Td (at ) Tj ET Q q 0 0 0 rg BT 223.94 446.10 Td (maturity ) Tj ET Q q 0 0 0 rg BT 260.73 446.10 Td (in ) Tj ET Q q 0 0 0 rg BT 271.41 446.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 296.60 446.10 Td (The ) Tj ET Q q 0 0 0 rg BT 315.06 446.10 Td (following ) Tj ET Q q 0 0 0 rg BT 356.85 446.10 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 407.51 446.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.64 446.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 442.76 446.10 Td (redemption ) Tj ET Q q 0 0 0 rg BT 491.20 446.10 Td (activity ) Tj ET Q q 0 0 0 rg BT 524.10 446.10 Td (for ) Tj ET Q q 0 0 0 rg BT 538.66 446.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 561.57 446.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 434.10 Td (2015 ) Tj ET Q q 0 0 0 rg BT 58.50 434.10 Td (\(none ) Tj ET Q q 0 0 0 rg BT 83.77 434.10 Td (in ) Tj ET Q q 0 0 0 rg BT 94.05 434.10 Td (2016\):) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 410.60 388.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 410.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 410.60 72.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 410.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 410.60 72.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 384.60 388.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 384.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 384.60 72.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 384.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 384.60 72.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 358.60 388.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 424.50 358.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 428.50 358.60 72.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 500.50 358.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 504.50 358.60 72.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 428.5 410.6 m 500.5 410.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 504.5 410.6 m 576.5 410.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 414.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 456.00 414.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.00 414.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 401.17 Td (Principal amount) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 431.00 401.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 401.17 Td (337) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.00 401.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 401.17 Td (1,624) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 388.17 Td (Carrying value) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 388.17 Td (366) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 388.17 Td (1,795) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 375.17 Td (Debt redemption price) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 375.17 Td (474) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 375.17 Td (1,957) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 362.17 Td (Notional amount of interest rate swap contracts terminated) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.65 362.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 362.17 Td (735) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 349.17 Td (Interest rate swap termination payments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.65 349.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 349.17 Td (1) Tj ET Q q 0 0 0 rg BT 567.65 349.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 336.17 Td (Loss on debt redemption) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 138.15 340.70 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.65 336.17 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 336.17 Td (180) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 317.50 Td (\(a\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 49.50 317.50 Td (Including ) Tj ET Q q 0 0 0 rg BT 82.16 317.50 Td (acceleration ) Tj ET Q q 0 0 0 rg BT 122.80 317.50 Td (of ) Tj ET Q q 0 0 0 rg BT 131.46 317.50 Td (debt ) Tj ET Q q 0 0 0 rg BT 147.23 317.50 Td (issuance ) Tj ET Q q 0 0 0 rg BT 176.34 317.50 Td (costs, ) Tj ET Q q 0 0 0 rg BT 196.34 317.50 Td (loss ) Tj ET Q q 0 0 0 rg BT 210.79 317.50 Td (on ) Tj ET Q q 0 0 0 rg BT 220.79 317.50 Td (interest ) Tj ET Q q 0 0 0 rg BT 246.33 317.50 Td (rate ) Tj ET Q q 0 0 0 rg BT 260.32 317.50 Td (lock ) Tj ET Q q 0 0 0 rg BT 276.09 317.50 Td (contract ) Tj ET Q q 0 0 0 rg BT 303.86 317.50 Td (and ) Tj ET Q q 0 0 0 rg BT 317.41 317.50 Td (other ) Tj ET Q q 0 0 0 rg BT 335.84 317.50 Td (related ) Tj ET Q q 0 0 0 rg BT 359.61 317.50 Td (fees.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.50 Td (Interest ) Tj ET Q q 0 0 0 rg BT 68.40 293.50 Td (payments ) Tj ET Q q 0 0 0 rg BT 109.14 293.50 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 130.99 293.50 Td ($215 ) Tj ET Q q 0 0 0 rg BT 153.41 293.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 182.30 293.50 Td ( ) Tj ET Q q 0 0 0 rg BT 184.72 293.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 194.91 293.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.91 293.50 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.83 293.50 Td ($191 ) Tj ET Q q 0 0 0 rg BT 242.25 293.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 271.14 293.50 Td ( ) Tj ET Q q 0 0 0 rg BT 273.55 293.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 283.75 293.50 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 303.75 293.50 Td ( ) Tj ET Q q 0 0 0 rg BT 306.17 293.50 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.02 293.50 Td ($205 ) Tj ET Q q 0 0 0 rg BT 345.44 293.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 374.33 293.50 Td ( ) Tj ET Q q 0 0 0 rg BT 376.75 293.50 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 386.94 293.50 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 406.94 293.50 Td ( ) Tj ET Q q 0 0 0 rg BT 409.36 293.50 Td (net ) Tj ET Q q 0 0 0 rg BT 423.99 293.50 Td (of ) Tj ET Q q 0 0 0 rg BT 434.74 293.50 Td (amounts ) Tj ET Q q 0 0 0 rg BT 471.04 293.50 Td (received ) Tj ET Q q 0 0 0 rg BT 507.32 293.50 Td (from ) Tj ET Q q 0 0 0 rg BT 529.18 293.50 Td (interest ) Tj ET Q q 0 0 0 rg BT 561.03 293.50 Td (rate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 281.50 Td (swap ) Tj ET Q q 0 0 0 rg BT 59.05 281.50 Td (contracts.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 257.50 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 257.50 Td (e ) Tj ET Q q 0 0 0 rg BT 52.04 257.50 Td (currently ) Tj ET Q q 0 0 0 rg BT 91.09 257.50 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 112.92 257.50 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 132.91 257.50 Td ( ) Tj ET Q q 0 0 0 rg BT 135.87 257.50 Td (separate ) Tj ET Q q 0 0 0 rg BT 171.58 257.50 Td (revolving ) Tj ET Q q 0 0 0 rg BT 212.87 257.50 Td (credit ) Tj ET Q q 0 0 0 rg BT 238.59 257.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 275.98 257.50 Td (totaling ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.49 257.50 Td ($5.0 ) Tj ET Q q 0 0 0 rg BT 329.95 257.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 356.06 257.50 Td ( ) Tj ET Q q 0 0 0 rg BT 359.02 257.50 Td (from ) Tj ET Q q 0 0 0 rg BT 381.42 257.50 Td (a ) Tj ET Q q 0 0 0 rg BT 388.81 257.50 Td (syndicate ) Tj ET Q q 0 0 0 rg BT 429.54 257.50 Td (of ) Tj ET Q q 0 0 0 rg BT 440.82 257.50 Td (lenders. ) Tj ET Q q 0 0 0 rg BT 474.95 257.50 Td (The ) Tj ET Q q 0 0 0 rg BT 493.45 257.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 530.84 257.50 Td (provide ) Tj ET Q q 0 0 0 rg BT 564.35 257.50 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 245.50 Td (customary ) Tj ET Q q 0 0 0 rg BT 80.27 245.50 Td (terms ) Tj ET Q q 0 0 0 rg BT 105.09 245.50 Td (and ) Tj ET Q q 0 0 0 rg BT 122.14 245.50 Td (conditions ) Tj ET Q q 0 0 0 rg BT 166.42 245.50 Td (with ) Tj ET Q q 0 0 0 rg BT 186.81 245.50 Td (no ) Tj ET Q q 0 0 0 rg BT 199.42 245.50 Td (financial ) Tj ET Q q 0 0 0 rg BT 237.01 245.50 Td (covenants. ) Tj ET Q q 0 0 0 rg BT 282.11 245.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 300.27 245.50 Td (364 ) Tj ET Q q 0 0 0 rg BT 317.88 245.50 Td (day ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 334.93 245.50 Td ($2.0 ) Tj ET Q q 0 0 0 rg BT 355.05 245.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.16 245.50 Td ( ) Tj ET Q q 0 0 0 rg BT 383.77 245.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 414.70 245.50 Td (expires ) Tj ET Q q 0 0 0 rg BT 446.19 245.50 Td (in ) Tj ET Q q 0 0 0 rg BT 456.58 245.50 Td (March ) Tj ET Q q 0 0 0 rg BT 485.29 245.50 Td (2018 ) Tj ET Q q 0 0 0 rg BT 507.90 245.50 Td (and ) Tj ET Q q 0 0 0 rg BT 524.95 245.50 Td (our ) Tj ET Q q 0 0 0 rg BT 540.89 245.50 Td (two ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.50 245.50 Td ($1.5 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 233.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 62.11 233.50 Td ( ) Tj ET Q q 0 0 0 rg BT 64.55 233.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 101.42 233.50 Td (were ) Tj ET Q q 0 0 0 rg BT 123.29 233.50 Td (extended ) Tj ET Q q 0 0 0 rg BT 161.82 233.50 Td (to ) Tj ET Q q 0 0 0 rg BT 172.04 233.50 Td (October ) Tj ET Q q 0 0 0 rg BT 206.68 233.50 Td (2021 ) Tj ET Q q 0 0 0 rg BT 229.12 233.50 Td (and ) Tj ET Q q 0 0 0 rg BT 246.00 233.50 Td (July ) Tj ET Q q 0 0 0 rg BT 265.11 233.50 Td (2022. ) Tj ET Q q 0 0 0 rg BT 290.05 233.50 Td (Our ) Tj ET Q q 0 0 0 rg BT 308.04 233.50 Td (two ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.48 233.50 Td ($1.5 ) Tj ET Q q 0 0 0 rg BT 345.42 233.50 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 371.53 233.50 Td (, ) Tj ET Q q 0 0 0 rg BT 376.47 233.50 Td (five-year ) Tj ET Q q 0 0 0 rg BT 414.99 233.50 Td (facilities ) Tj ET Q q 0 0 0 rg BT 451.86 233.50 Td (are ) Tj ET Q q 0 0 0 rg BT 466.51 233.50 Td (extendable ) Tj ET Q q 0 0 0 rg BT 512.25 233.50 Td (annually ) Tj ET Q q 0 0 0 rg BT 549.13 233.50 Td (by ) Tj ET Q q 0 0 0 rg BT 561.57 233.50 Td (one ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.50 Td (year ) Tj ET Q q 0 0 0 rg BT 56.56 221.50 Td (on ) Tj ET Q q 0 0 0 rg BT 69.92 221.50 Td (the ) Tj ET Q q 0 0 0 rg BT 85.49 221.50 Td (anniversary ) Tj ET Q q 0 0 0 rg BT 135.49 221.50 Td (date ) Tj ET Q q 0 0 0 rg BT 155.50 221.50 Td (with ) Tj ET Q q 0 0 0 rg BT 176.64 221.50 Td (the ) Tj ET Q q 0 0 0 rg BT 192.21 221.50 Td (consent ) Tj ET Q q 0 0 0 rg BT 226.11 221.50 Td (of ) Tj ET Q q 0 0 0 rg BT 237.80 221.50 Td (the ) Tj ET Q q 0 0 0 rg BT 253.37 221.50 Td (lenders. ) Tj ET Q q 0 0 0 rg BT 288.11 221.50 Td (No ) Tj ET Q q 0 0 0 rg BT 303.68 221.50 Td (borrowings ) Tj ET Q q 0 0 0 rg BT 352.59 221.50 Td (were ) Tj ET Q q 0 0 0 rg BT 375.38 221.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 425.40 221.50 Td (under ) Tj ET Q q 0 0 0 rg BT 451.52 221.50 Td (any ) Tj ET Q q 0 0 0 rg BT 469.32 221.50 Td (revolving ) Tj ET Q q 0 0 0 rg BT 511.00 221.50 Td (credit ) Tj ET Q q 0 0 0 rg BT 537.12 221.50 Td (facility ) Tj ET Q q 0 0 0 rg BT 568.79 221.50 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 209.50 Td (December ) Tj ET Q q 0 0 0 rg BT 79.58 209.50 Td (31, ) Tj ET Q q 0 0 0 rg BT 94.58 209.50 Td (2017 ) Tj ET Q q 0 0 0 rg BT 117.08 209.50 Td (or ) Tj ET Q q 0 0 0 rg BT 127.91 209.50 Td (2016.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 185.50 Td (A) Tj ET Q q 0 0 0 rg BT 42.48 185.50 Td (vailable ) Tj ET Q q 0 0 0 rg BT 75.73 185.50 Td (financial ) Tj ET Q q 0 0 0 rg BT 112.31 185.50 Td (guarantees ) Tj ET Q q 0 0 0 rg BT 156.66 185.50 Td (provided ) Tj ET Q q 0 0 0 rg BT 193.81 185.50 Td (in ) Tj ET Q q 0 0 0 rg BT 203.19 185.50 Td (the ) Tj ET Q q 0 0 0 rg BT 217.00 185.50 Td (form ) Tj ET Q q 0 0 0 rg BT 238.04 185.50 Td (of ) Tj ET Q q 0 0 0 rg BT 247.97 185.50 Td (stand-by ) Tj ET Q q 0 0 0 rg BT 284.01 185.50 Td (letters ) Tj ET Q q 0 0 0 rg BT 310.04 185.50 Td (of ) Tj ET Q q 0 0 0 rg BT 319.97 185.50 Td (credit ) Tj ET Q q 0 0 0 rg BT 344.33 185.50 Td (and ) Tj ET Q q 0 0 0 rg BT 360.37 185.50 Td (performance ) Tj ET Q q 0 0 0 rg BT 412.49 185.50 Td (bonds ) Tj ET Q q 0 0 0 rg BT 437.98 185.50 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.01 185.50 Td ($704 ) Tj ET Q q 0 0 0 rg BT 480.61 185.50 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.50 185.50 Td ( ) Tj ET Q q 0 0 0 rg BT 511.10 185.50 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.91 185.50 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 173.50 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 56.00 173.50 Td (. ) Tj ET Q q 0 0 0 rg BT 61.45 173.50 Td (Stand-by ) Tj ET Q q 0 0 0 rg BT 100.51 173.50 Td (letters ) Tj ET Q q 0 0 0 rg BT 127.89 173.50 Td (of ) Tj ET Q q 0 0 0 rg BT 139.17 173.50 Td (credit ) Tj ET Q q 0 0 0 rg BT 164.88 173.50 Td (are ) Tj ET Q q 0 0 0 rg BT 180.04 173.50 Td (issued ) Tj ET Q q 0 0 0 rg BT 207.99 173.50 Td (through ) Tj ET Q q 0 0 0 rg BT 242.04 173.50 Td (financial ) Tj ET Q q 0 0 0 rg BT 279.97 173.50 Td (institutions ) Tj ET Q q 0 0 0 rg BT 327.38 173.50 Td (in ) Tj ET Q q 0 0 0 rg BT 338.10 173.50 Td (support ) Tj ET Q q 0 0 0 rg BT 371.05 173.50 Td (of ) Tj ET Q q 0 0 0 rg BT 382.33 173.50 Td (guarantees ) Tj ET Q q 0 0 0 rg BT 428.04 173.50 Td (for ) Tj ET Q q 0 0 0 rg BT 442.65 173.50 Td (various ) Tj ET Q q 0 0 0 rg BT 475.03 173.50 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 524.93 173.50 Td (Performance ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 161.50 Td (bonds ) Tj ET Q q 0 0 0 rg BT 61.78 161.50 Td (are ) Tj ET Q q 0 0 0 rg BT 75.87 161.50 Td (issued ) Tj ET Q q 0 0 0 rg BT 102.75 161.50 Td (to ) Tj ET Q q 0 0 0 rg BT 112.41 161.50 Td (support ) Tj ET Q q 0 0 0 rg BT 144.30 161.50 Td (a ) Tj ET Q q 0 0 0 rg BT 150.62 161.50 Td (range ) Tj ET Q q 0 0 0 rg BT 174.71 161.50 Td (of ) Tj ET Q q 0 0 0 rg BT 184.92 161.50 Td (ongoing ) Tj ET Q q 0 0 0 rg BT 219.58 161.50 Td (operating ) Tj ET Q q 0 0 0 rg BT 259.23 161.50 Td (activities, ) Tj ET Q q 0 0 0 rg BT 299.71 161.50 Td (including ) Tj ET Q q 0 0 0 rg BT 339.37 161.50 Td (sale ) Tj ET Q q 0 0 0 rg BT 356.80 161.50 Td (of ) Tj ET Q q 0 0 0 rg BT 367.02 161.50 Td (products ) Tj ET Q q 0 0 0 rg BT 403.34 161.50 Td (to ) Tj ET Q q 0 0 0 rg BT 413.00 161.50 Td (hospitals ) Tj ET Q q 0 0 0 rg BT 450.44 161.50 Td (and ) Tj ET Q q 0 0 0 rg BT 466.76 161.50 Td (foreign ) Tj ET Q q 0 0 0 rg BT 497.52 161.50 Td (ministries ) Tj ET Q q 0 0 0 rg BT 538.85 161.50 Td (of ) Tj ET Q q 0 0 0 rg BT 549.07 161.50 Td (health, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 149.50 Td (bonds ) Tj ET Q q 0 0 0 rg BT 63.66 149.50 Td (for ) Tj ET Q q 0 0 0 rg BT 79.08 149.50 Td (customs, ) Tj ET Q q 0 0 0 rg BT 118.13 149.50 Td (duties ) Tj ET Q q 0 0 0 rg BT 145.78 149.50 Td (and ) Tj ET Q q 0 0 0 rg BT 163.98 149.50 Td (value ) Tj ET Q q 0 0 0 rg BT 189.40 149.50 Td (added ) Tj ET Q q 0 0 0 rg BT 217.04 149.50 Td (tax ) Tj ET Q q 0 0 0 rg BT 233.03 149.50 Td (and ) Tj ET Q q 0 0 0 rg BT 251.23 149.50 Td (guarantees ) Tj ET Q q 0 0 0 rg BT 297.75 149.50 Td (related ) Tj ET Q q 0 0 0 rg BT 328.72 149.50 Td (to ) Tj ET Q q 0 0 0 rg BT 340.26 149.50 Td (miscellaneous ) Tj ET Q q 0 0 0 rg BT 400.67 149.50 Td (legal ) Tj ET Q q 0 0 0 rg BT 423.87 149.50 Td (actions. ) Tj ET Q q 0 0 0 rg BT 457.63 149.50 Td (A) Tj ET Q q 0 0 0 rg BT 464.30 149.50 Td ( ) Tj ET Q q 0 0 0 rg BT 468.07 149.50 Td (significant ) Tj ET Q q 0 0 0 rg BT 514.04 149.50 Td (majority ) Tj ET Q q 0 0 0 rg BT 551.69 149.50 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 149.50 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 137.50 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 85.17 137.50 Td (financial ) Tj ET Q q 0 0 0 rg BT 122.65 137.50 Td (guarantees ) Tj ET Q q 0 0 0 rg BT 167.90 137.50 Td (will ) Tj ET Q q 0 0 0 rg BT 185.96 137.50 Td (expire ) Tj ET Q q 0 0 0 rg BT 213.44 137.50 Td (within ) Tj ET Q q 0 0 0 rg BT 241.50 137.50 Td (the ) Tj ET Q q 0 0 0 rg BT 256.21 137.50 Td (year ) Tj ET Q q 0 0 0 rg BT 275.92 137.50 Td (and ) Tj ET Q q 0 0 0 rg BT 292.86 137.50 Td (are ) Tj ET Q q 0 0 0 rg BT 307.57 137.50 Td (not ) Tj ET Q q 0 0 0 rg BT 322.85 137.50 Td (expected ) Tj ET Q q 0 0 0 rg BT 360.88 137.50 Td (to ) Tj ET Q q 0 0 0 rg BT 371.16 137.50 Td (be ) Tj ET Q q 0 0 0 rg BT 383.09 137.50 Td (funded.) Tj ET Q endstream endobj 179 0 obj <> endobj 180 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (89) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 749.25 Td (10) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 749.25 Td (. RECEIV) Tj ET Q q 0 0 0 rg BT 111.10 749.25 Td (ABLES) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 702.75 373.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 702.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 702.75 79.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 702.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 702.75 80.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 674.75 373.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 674.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 674.75 79.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 674.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 674.75 80.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 646.75 373.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 646.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 646.75 79.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 646.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 646.75 80.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 618.75 373.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 618.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 618.75 79.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 618.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 618.75 80.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 714.75 m 492.5 714.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 492.5 714.75 m 496.5 714.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 714.75 m 576.5 714.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 702.75 m 492.5 702.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 702.75 m 576.5 702.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i 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ET q 0 0 0 rg BT 39.00 693.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.93 693.32 Td (rade receivables) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 693.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 693.32 Td (4,599) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 693.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 693.32 Td (3,948) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 679.32 Td (Less char) Tj ET Q q 0 0 0 rg BT 76.95 679.32 Td (ge-backs and cash discounts) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.30 679.37 Td (\(209) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 679.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 679.32 Td (\(126) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 679.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 665.32 Td (Less bad debt allowances) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.30 665.37 Td (\(43) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 665.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 665.32 Td (\(48) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 665.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 651.32 Td (Net trade receivables) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 651.32 Td (4,347) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 651.32 Td (3,774) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 637.32 Td (Alliance receivables) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 637.32 Td (522) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 637.32 Td (903) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 623.32 Td (Prepaid and refundable income taxes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 623.32 Td (691) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 623.32 Td (627) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 609.32 Td (Royalties, ) Tj ET Q q 0 0 0 rg BT 81.68 609.32 Td (V) Tj ET Q q 0 0 0 rg BT 88.17 609.32 Td (A) Tj ET Q q 0 0 0 rg BT 94.19 609.32 Td (T) Tj ET Q q 0 0 0 rg BT 99.66 609.32 Td ( and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 609.32 Td (740) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 609.32 Td (239) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 595.32 Td (Receivables) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 595.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 595.32 Td (6,300) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 595.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 595.32 Td (5,543) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 567.25 Td (Non-U.S. ) Tj ET Q q 0 0 0 rg BT 77.28 567.25 Td (receivables ) Tj ET Q q 0 0 0 rg BT 125.20 567.25 Td (sold ) Tj ET Q q 0 0 0 rg BT 144.81 567.25 Td (on ) Tj ET Q q 0 0 0 rg BT 157.76 567.25 Td (a ) Tj ET Q q 0 0 0 rg BT 165.14 567.25 Td (nonrecourse ) Tj ET Q q 0 0 0 rg BT 216.96 567.25 Td (basis ) Tj ET Q q 0 0 0 rg BT 239.90 567.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.28 567.25 Td ($637 ) Tj ET Q q 0 0 0 rg BT 285.22 567.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 314.11 567.25 Td ( ) Tj ET Q q 0 0 0 rg BT 317.06 567.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.78 567.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.78 567.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.23 567.25 Td ($618 ) Tj ET Q q 0 0 0 rg BT 376.18 567.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.07 567.25 Td ( ) Tj ET Q q 0 0 0 rg BT 408.01 567.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.74 567.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.74 567.25 Td (, ) Tj ET Q q 0 0 0 rg BT 444.18 567.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.57 567.25 Td ($476 ) Tj ET Q q 0 0 0 rg BT 484.51 567.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.40 567.25 Td ( ) Tj ET Q q 0 0 0 rg BT 516.35 567.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 527.07 567.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 547.07 567.25 Td (. ) Tj ET Q q 0 0 0 rg BT 552.52 567.25 Td (In ) Tj ET Q q 0 0 0 rg BT 563.80 567.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 555.25 Td (aggregate, ) Tj ET Q q 0 0 0 rg BT 81.64 555.25 Td (receivables ) Tj ET Q q 0 0 0 rg BT 130.89 555.25 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 154.60 555.25 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 174.59 555.25 Td ( ) Tj ET Q q 0 0 0 rg BT 178.87 555.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 244.22 555.25 Td (wholesalers ) Tj ET Q q 0 0 0 rg BT 295.71 555.25 Td (in ) Tj ET Q q 0 0 0 rg BT 307.76 555.25 Td (the ) Tj ET Q q 0 0 0 rg BT 324.26 555.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 346.32 555.25 Td (represented ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 396.68 555.25 Td (65%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.01 555.25 Td ( ) Tj ET Q q 0 0 0 rg BT 419.29 555.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.00 555.25 Td (66%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 456.33 555.25 Td ( ) Tj ET Q q 0 0 0 rg BT 460.61 555.25 Td (of ) Tj ET Q q 0 0 0 rg BT 473.22 555.25 Td (total ) Tj ET Q q 0 0 0 rg BT 495.27 555.25 Td (trade ) Tj ET Q q 0 0 0 rg BT 519.53 555.25 Td (receivables ) Tj ET Q q 0 0 0 rg BT 568.78 555.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 543.25 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 94.58 543.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 114.58 543.25 Td ( ) Tj ET Q q 0 0 0 rg BT 117.08 543.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 134.02 543.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 154.02 543.25 Td (, ) Tj ET Q q 0 0 0 rg BT 159.02 543.25 Td (respectively) Tj ET Q q 0 0 0 rg BT 206.68 543.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 519.25 Td (Changes to the allowances for bad debt, char) Tj ET Q q 0 0 0 rg BT 215.20 519.25 Td (ge-backs and cash discounts were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 484.75 321.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 484.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 484.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 484.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 484.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 484.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 484.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 456.75 321.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 456.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 456.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 456.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 456.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 456.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 456.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 428.75 321.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 428.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 428.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 428.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 428.75 69.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 428.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 428.75 69.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 496.75 m 429.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 429.5 496.75 m 433.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 496.75 m 502.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 502.5 496.75 m 506.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 496.75 m 575.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 496.75 m 429.5 496.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 484.75 m 429.5 484.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 484.75 m 502.5 484.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 484.75 m 575.5 484.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 484.75 m 502.5 484.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 484.75 m 575.5 484.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 428.75 m 429.5 428.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 415.75 m 429.5 415.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 413.75 m 429.5 413.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 428.75 m 502.5 428.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 415.75 m 502.5 415.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 413.75 m 502.5 413.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 428.75 m 575.5 428.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 415.75 m 575.5 415.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 413.75 m 575.5 413.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 500.70 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 423.20 500.83 Td (Y) Tj ET Q q 0 0 0 rg BT 428.53 500.83 Td (ear) Tj ET Q q 0 0 0 rg BT 439.12 500.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 499.85 500.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 488.70 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 386.50 488.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 459.50 488.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 488.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 475.32 Td (Balance at beginning of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 475.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 475.32 Td (174) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 475.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 475.32 Td (122) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 475.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 475.32 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 461.32 Td (Provision) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 461.32 Td (2,090) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.15 461.32 Td (1,613) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 461.32 Td (1,059) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 447.32 Td (Utilization) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 447.37 Td (\(2,015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 447.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.80 447.37 Td (\(1,561) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.65 447.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.80 447.32 Td (\(1,030) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 447.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 433.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 433.32 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 433.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 433.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 38.00 419.32 Td (Balance at end of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.00 419.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.65 419.32 Td (252) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.00 419.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.65 419.32 Td (174) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.00 419.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 419.32 Td (122) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 389.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 389.25 Td (1) Tj ET Q q 0 0 0 rg BT 62.94 389.25 Td (1) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 67.94 389.25 Td (. INVENT) Tj ET Q q 0 0 0 rg BT 111.65 389.25 Td (ORIES) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 342.75 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 342.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 342.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 342.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 342.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 314.75 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 314.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 314.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 314.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 314.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 286.75 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 286.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 286.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 286.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 286.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 258.75 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 258.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 258.75 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 258.75 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 258.75 81.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 354.75 m 491.5 354.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 491.5 354.75 m 495.5 354.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 354.75 m 576.5 354.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 342.75 m 491.5 342.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 342.75 m 576.5 342.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 300.75 m 491.5 300.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 287.75 m 491.5 287.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 285.75 m 491.5 285.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 300.75 m 576.5 300.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 287.75 m 576.5 287.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 285.75 m 576.5 285.75 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 469.75 358.83 Td (December) Tj ET Q q 0 0 0 rg BT 504.32 358.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 346.70 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 442.50 346.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 527.50 346.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 333.32 Td (Finished goods) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.00 333.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 333.32 Td (384) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 333.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 333.32 Td (310) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 319.32 Td (W) Tj ET Q q 0 0 0 rg BT 48.04 319.32 Td (ork in process) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 319.32 Td (931) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 319.32 Td (988) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 305.32 Td (Raw and packaging materials) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 305.32 Td (273) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 305.32 Td (264) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 291.32 Td (Inventories) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.00 291.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.15 291.32 Td (1,588) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 291.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 291.32 Td (1,562) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 263.32 Td (Inventories) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.00 263.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.15 263.32 Td (1,166) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 263.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 263.32 Td (1,241) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 249.32 Td (Other assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 249.32 Td (422) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 249.32 Td (321) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 221.25 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.27 221.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 87.10 221.25 Td (include ) Tj ET Q q 0 0 0 rg BT 119.03 221.25 Td (inventory ) Tj ET Q q 0 0 0 rg BT 159.86 221.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 197.89 221.25 Td (to ) Tj ET Q q 0 0 0 rg BT 208.17 221.25 Td (remain ) Tj ET Q q 0 0 0 rg BT 238.43 221.25 Td (on ) Tj ET Q q 0 0 0 rg BT 250.93 221.25 Td (hand ) Tj ET Q q 0 0 0 rg BT 272.87 221.25 Td (beyond ) Tj ET Q q 0 0 0 rg BT 304.81 221.25 Td (one ) Tj ET Q q 0 0 0 rg BT 321.75 221.25 Td (year ) Tj ET Q q 0 0 0 rg BT 341.45 221.25 Td (in ) Tj ET Q q 0 0 0 rg BT 351.73 221.25 Td (both ) Tj ET Q q 0 0 0 rg BT 372.01 221.25 Td (periods.) 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505.82 718.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 706.70 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.50 706.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.00 706.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 693.32 Td (Land) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 693.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 693.32 Td (100) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 693.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 693.32 Td (107) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 679.32 Td (Buildings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 679.32 Td (4,848) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 679.32 Td (4,930) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 665.32 Td (Machinery) Tj ET Q q 0 0 0 rg BT 81.99 665.32 Td (, equipment and fixtures) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 665.32 Td (3,059) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 665.32 Td (3,287) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 651.32 Td (Construction in progress) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 651.32 Td (980) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 651.32 Td (849) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 637.32 Td (Gross property) Tj ET Q q 0 0 0 rg BT 98.39 637.32 Td (, plant and equipment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 637.32 Td (8,987) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 637.32 Td (9,173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 623.32 Td (Less accumulated depreciation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.80 623.37 Td (\(3,986) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 623.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 623.32 Td (\(4,193) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 623.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 609.32 Td (Property) Tj ET Q q 0 0 0 rg BT 72.79 609.32 Td (, plant and equipment) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 609.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 609.32 Td (5,001) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 609.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 609.32 Td (4,980) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (Depreciation ) Tj ET Q q 0 0 0 rg BT 90.14 581.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 124.85 581.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 142.90 581.25 Td ($682 ) Tj ET Q q 0 0 0 rg BT 165.40 581.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 194.29 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 196.79 581.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 207.07 581.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 227.07 581.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 232.07 581.25 Td ($448 ) Tj ET Q q 0 0 0 rg BT 254.57 581.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 283.46 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 285.96 581.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 296.24 581.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 316.24 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 318.74 581.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.68 581.25 Td ($500 ) Tj ET Q q 0 0 0 rg BT 358.18 581.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.07 581.25 Td ( ) Tj ET Q q 0 0 0 rg BT 389.57 581.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.85 581.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.85 581.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (Gross ) Tj ET Q q 0 0 0 rg BT 62.03 557.25 Td (property) Tj ET Q q 0 0 0 rg BT 95.26 557.25 Td (, ) Tj ET Q q 0 0 0 rg BT 100.45 557.25 Td (plant ) Tj ET Q q 0 0 0 rg BT 123.14 557.25 Td (and ) Tj ET Q q 0 0 0 rg BT 140.27 557.25 Td (equipment ) Tj ET Q q 0 0 0 rg BT 185.18 557.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 196.20 557.25 Td ($475 ) Tj ET Q q 0 0 0 rg BT 218.90 557.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 247.79 557.25 Td ( ) Tj ET Q q 0 0 0 rg BT 250.48 557.25 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 253.81 557.25 Td ($85 ) Tj ET Q q 0 0 0 rg BT 271.51 557.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.40 557.25 Td ( ) Tj ET Q q 0 0 0 rg BT 303.09 557.25 Td (net ) Tj ET Q q 0 0 0 rg BT 318.01 557.25 Td (of ) Tj ET Q q 0 0 0 rg BT 329.03 557.25 Td (accumulated ) Tj ET Q q 0 0 0 rg BT 382.25 557.25 Td (depreciation\) ) Tj ET Q q 0 0 0 rg BT 437.70 557.25 Td (was ) Tj ET Q q 0 0 0 rg BT 455.94 557.25 Td (reclassified ) Tj ET Q q 0 0 0 rg BT 504.17 557.25 Td (to ) Tj ET Q q 0 0 0 rg BT 514.64 557.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 540.67 557.25 Td (held-for) Tj ET Q q 0 0 0 rg BT 572.67 557.25 Td (-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 545.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 53.50 545.25 Td (at ) Tj ET Q q 0 0 0 rg BT 62.67 545.25 Td (December ) Tj ET Q q 0 0 0 rg BT 105.71 545.25 Td (31, ) Tj ET Q q 0 0 0 rg BT 120.17 545.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 142.12 545.25 Td (as ) Tj ET Q q 0 0 0 rg BT 152.41 545.25 Td (a ) Tj ET Q q 0 0 0 rg BT 158.80 545.25 Td (result ) Tj ET Q q 0 0 0 rg BT 182.97 545.25 Td (of ) Tj ET Q q 0 0 0 rg BT 193.25 545.25 Td (the ) Tj ET Q q 0 0 0 rg BT 207.43 545.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 241.60 545.25 Td (sale ) Tj ET Q q 0 0 0 rg BT 259.10 545.25 Td (of ) Tj ET Q q 0 0 0 rg BT 269.38 545.25 Td (a ) Tj ET Q q 0 0 0 rg BT 275.78 545.25 Td (R&D ) Tj ET Q q 0 0 0 rg BT 299.40 545.25 Td (facility ) Tj ET Q q 0 0 0 rg BT 329.68 545.25 Td (in ) Tj ET Q q 0 0 0 rg BT 339.27 545.25 Td (W) Tj ET Q q 0 0 0 rg BT 347.90 545.25 Td (allingford, ) Tj ET Q q 0 0 0 rg BT 391.79 545.25 Td (Connecticut. ) Tj ET Q q 0 0 0 rg BT 444.57 545.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 468.73 545.25 Td (to ) Tj ET Q q 0 0 0 rg BT 478.46 545.25 Td ("—Note ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 513.94 545.25 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.94 545.25 Td (. ) Tj ET Q q 0 0 0 rg BT 522.96 545.25 Td (Acquisitions, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 533.25 Td (Divestitures ) Tj ET Q q 0 0 0 rg BT 86.83 533.25 Td (and ) Tj ET Q q 0 0 0 rg BT 103.76 533.25 Td (Licensing ) Tj ET Q q 0 0 0 rg BT 145.15 533.25 Td (Arrangements" ) Tj ET Q q 0 0 0 rg BT 208.37 533.25 Td (for ) Tj ET Q q 0 0 0 rg BT 222.53 533.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 265.02 533.25 Td (information.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 509.25 Td (Annual ) Tj ET Q q 0 0 0 rg BT 67.97 509.25 Td (minimum ) Tj ET Q q 0 0 0 rg BT 109.39 509.25 Td (rental ) Tj ET Q q 0 0 0 rg BT 134.69 509.25 Td (commitments ) Tj ET Q q 0 0 0 rg BT 191.66 509.25 Td (for ) Tj ET Q q 0 0 0 rg BT 205.85 509.25 Td (non-cancelable ) Tj ET Q q 0 0 0 rg BT 268.90 509.25 Td (operating ) Tj ET Q q 0 0 0 rg BT 309.20 509.25 Td (leases ) Tj ET Q q 0 0 0 rg BT 335.60 509.25 Td (\(primarily ) Tj ET Q q 0 0 0 rg BT 378.68 509.25 Td (real ) Tj ET Q q 0 0 0 rg BT 396.20 509.25 Td (estate ) Tj ET Q q 0 0 0 rg BT 421.49 509.25 Td (and ) Tj ET Q q 0 0 0 rg BT 438.46 509.25 Td (motor ) Tj ET Q q 0 0 0 rg BT 464.88 509.25 Td (vehicles\) ) Tj ET Q q 0 0 0 rg BT 503.50 509.25 Td (are ) Tj ET Q q 0 0 0 rg BT 518.24 509.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 497.25 Td ($100 ) Tj ET Q q 0 0 0 rg BT 58.66 497.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.55 497.25 Td ( ) Tj ET Q q 0 0 0 rg BT 90.22 497.25 Td (in ) Tj ET Q q 0 0 0 rg BT 100.66 497.25 Td (each ) Tj ET Q q 0 0 0 rg BT 121.64 497.25 Td (of ) Tj ET Q q 0 0 0 rg BT 132.63 497.25 Td (the ) Tj ET Q q 0 0 0 rg BT 147.51 497.25 Td (next ) Tj ET Q q 0 0 0 rg BT 167.39 497.25 Td (five ) Tj ET Q q 0 0 0 rg BT 185.60 497.25 Td (years ) Tj ET Q q 0 0 0 rg BT 209.36 497.25 Td (and ) Tj ET Q q 0 0 0 rg BT 226.46 497.25 Td (an ) Tj ET Q q 0 0 0 rg BT 238.56 497.25 Td (aggregate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 280.08 497.25 Td ($300 ) Tj ET Q q 0 0 0 rg BT 302.75 497.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.64 497.25 Td ( ) Tj ET Q q 0 0 0 rg BT 334.30 497.25 Td (thereafter) Tj ET Q q 0 0 0 rg BT 372.05 497.25 Td (. ) Tj ET Q q 0 0 0 rg BT 377.21 497.25 Td (Operating ) Tj ET Q q 0 0 0 rg BT 419.86 497.25 Td (lease ) Tj ET Q q 0 0 0 rg BT 442.51 497.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 477.38 497.25 Td (was ) Tj ET Q q 0 0 0 rg BT 495.59 497.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.01 497.25 Td ($120 ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 485.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 64.89 485.25 Td ( ) Tj ET Q q 0 0 0 rg BT 67.32 485.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 77.53 485.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 97.53 485.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 102.46 485.25 Td ($145 ) Tj ET Q q 0 0 0 rg BT 124.89 485.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 153.78 485.25 Td ( ) Tj ET Q q 0 0 0 rg BT 156.21 485.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 166.42 485.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 186.42 485.25 Td ( ) Tj ET Q q 0 0 0 rg BT 188.84 485.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.71 485.25 Td ($140 ) Tj ET Q q 0 0 0 rg BT 228.14 485.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 257.03 485.25 Td ( ) Tj ET Q q 0 0 0 rg BT 259.46 485.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 269.67 485.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 289.67 485.25 Td (. ) Tj ET Q q 0 0 0 rg BT 294.60 485.25 Td (Sublease ) Tj ET Q q 0 0 0 rg BT 332.57 485.25 Td (income ) Tj ET Q q 0 0 0 rg BT 364.44 485.25 Td (and ) Tj ET Q q 0 0 0 rg BT 381.31 485.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 410.38 485.25 Td (lease ) Tj ET Q q 0 0 0 rg BT 432.80 485.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 479.67 485.25 Td (were ) Tj ET Q q 0 0 0 rg BT 501.53 485.25 Td (not ) Tj ET Q q 0 0 0 rg BT 516.74 485.25 Td (material ) Tj ET Q q 0 0 0 rg BT 551.93 485.25 Td (for ) Tj ET Q q 0 0 0 rg BT 566.01 485.25 Td (all ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 473.25 Td (periods ) Tj ET Q q 0 0 0 rg BT 67.94 473.25 Td (presented. ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 447.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 447.25 Td (13) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 447.25 Td (. GOODWILL) Tj ET Q q 0 0 0 rg BT 130.73 447.25 Td ( ) Tj ET Q q 0 0 0 rg BT 132.67 447.25 Td (AND OTHER INT) Tj ET Q q 0 0 0 rg BT 212.50 447.25 Td (ANGIBLE ) Tj ET Q q 0 0 0 rg BT 260.57 447.25 Td (ASSETS) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 393.75 315.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 350.50 393.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 393.75 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 393.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 393.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 393.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 393.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 367.75 315.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 350.50 367.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 367.75 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 367.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 367.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 367.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 367.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 341.75 315.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 350.50 341.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 341.75 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 341.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 341.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 341.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 341.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 315.75 315.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 350.50 315.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 315.75 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 315.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 315.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 315.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 315.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 289.75 315.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 350.50 289.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 354.50 289.75 55.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 289.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 289.75 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 289.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 289.75 79.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 412.75 m 492.5 412.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 492.5 412.75 m 496.5 412.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 412.75 m 575.5 412.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 354.5 393.75 m 409.5 393.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 393.75 m 492.5 393.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 393.75 m 575.5 393.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 302.75 m 492.5 302.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 302.75 m 575.5 302.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 276.75 m 492.5 276.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 276.75 m 575.5 276.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 264.75 m 492.5 264.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 262.75 m 492.5 262.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 264.75 m 575.5 264.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 262.75 m 575.5 262.75 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 470.75 416.83 Td (December) Tj ET Q q 0 0 0 rg BT 505.32 416.83 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 398.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 364.15 404.83 Td (Estimated) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 360.50 396.83 Td (Useful Lives) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.50 397.98 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 527.50 397.98 Td (2016) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 384.48 Td (Goodwill) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 384.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 384.32 Td (6,863) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 384.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 384.32 Td (6,875) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 38.00 358.48 Td (Other) Tj ET Q q 0 0 0 rg BT 63.37 358.48 Td ( intangible assets:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 345.32 Td (Licenses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.40 345.32 Td (5 – 15 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 345.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 345.32 Td (567) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 345.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 345.32 Td (564) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 332.32 Td (Developed technology rights) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.40 332.32 Td (9 – 15 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 332.32 Td (2,357) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 332.32 Td (2,357) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 319.32 Td (Capitalized software) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.40 319.32 Td (3 – 10 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 319.32 Td (1,381) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 319.32 Td (1,441) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 306.32 Td (IPRD) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 306.32 Td (32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 306.32 Td (107) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 293.32 Td (Gross other intangible assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 293.32 Td (4,337) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 293.32 Td (4,469) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 280.32 Td (Less accumulated amortization) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.80 280.37 Td (\(3,127) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.65 280.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.80 280.32 Td (\(3,084) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 280.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 47.00 267.32 Td (T) Tj ET Q q 0 0 0 rg BT 52.41 267.32 Td (otal other intangible assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 267.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 267.32 Td (1,210) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 267.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 549.15 267.32 Td (1,385) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 240.25 Td (Amortization ) Tj ET Q q 0 0 0 rg BT 91.44 240.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 125.77 240.25 Td (of ) Tj ET Q q 0 0 0 rg BT 136.22 240.25 Td (other ) Tj ET Q q 0 0 0 rg BT 158.89 240.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 201.00 240.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 226.45 240.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 244.12 240.25 Td ($190 ) Tj ET Q q 0 0 0 rg BT 266.24 240.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.13 240.25 Td ( ) Tj ET Q q 0 0 0 rg BT 297.25 240.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.15 240.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.15 240.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.77 240.25 Td ($178 ) Tj ET Q q 0 0 0 rg BT 353.89 240.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.79 240.25 Td ( ) Tj ET Q q 0 0 0 rg BT 384.91 240.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.80 240.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 414.80 240.25 Td ( ) Tj ET Q q 0 0 0 rg BT 416.93 240.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.48 240.25 Td ($183 ) Tj ET Q q 0 0 0 rg BT 455.60 240.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.50 240.25 Td ( ) Tj ET Q q 0 0 0 rg BT 486.62 240.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.52 240.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 516.52 240.25 Td (. ) Tj ET Q q 0 0 0 rg BT 521.14 240.25 Td (Future ) Tj ET Q q 0 0 0 rg BT 549.37 240.25 Td (annual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.25 Td (amortization ) Tj ET Q q 0 0 0 rg BT 88.57 228.25 Td (expense ) Tj ET Q q 0 0 0 rg BT 122.81 228.25 Td (of ) Tj ET Q q 0 0 0 rg BT 133.17 228.25 Td (other ) Tj ET Q q 0 0 0 rg BT 155.75 228.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 197.77 228.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 223.14 228.25 Td (is ) Tj ET Q q 0 0 0 rg BT 231.84 228.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 269.41 228.25 Td (to ) Tj ET Q q 0 0 0 rg BT 279.22 228.25 Td (be ) Tj ET Q q 0 0 0 rg BT 290.69 228.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 350.48 228.25 Td ($220 ) Tj ET Q q 0 0 0 rg BT 372.51 228.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.40 228.25 Td ( ) Tj ET Q q 0 0 0 rg BT 403.44 228.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.25 228.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.25 228.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.78 228.25 Td ($200 ) Tj ET Q q 0 0 0 rg BT 459.81 228.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 488.70 228.25 Td ( ) Tj ET Q q 0 0 0 rg BT 490.74 228.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.55 228.25 Td (2019) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.55 228.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.08 228.25 Td ($160 ) Tj ET Q q 0 0 0 rg BT 547.11 228.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.63 216.25 Td (2020) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 65.63 216.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 69.99 216.25 Td ($130 ) Tj ET Q q 0 0 0 rg BT 91.84 216.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 120.74 216.25 Td ( ) Tj ET Q q 0 0 0 rg BT 122.59 216.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 132.23 216.25 Td (2021) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 152.23 216.25 Td (, ) Tj ET Q q 0 0 0 rg BT 156.58 216.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 172.88 216.25 Td ($100 ) Tj ET Q q 0 0 0 rg BT 194.73 216.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 223.62 216.25 Td ( ) Tj ET Q q 0 0 0 rg BT 225.48 216.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 235.11 216.25 Td (2022) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 255.11 216.25 Td (. ) Tj ET Q q 0 0 0 rg BT 259.47 216.25 Td (Other ) Tj ET Q q 0 0 0 rg BT 284.09 216.25 Td (intangible ) Tj ET Q q 0 0 0 rg BT 325.94 216.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 347.23 216.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 395.18 216.25 Td (char) Tj ET Q q 0 0 0 rg BT 412.21 216.25 Td (ges ) Tj ET Q q 0 0 0 rg BT 427.40 216.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.68 216.25 Td ($80 ) Tj ET Q q 0 0 0 rg BT 465.54 216.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.43 216.25 Td ( ) Tj ET Q q 0 0 0 rg BT 496.28 216.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 505.92 216.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.92 216.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 530.27 216.25 Td ($33 ) Tj ET Q q 0 0 0 rg BT 547.13 216.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 46.28 204.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.28 204.25 Td ( ) Tj ET Q q 0 0 0 rg BT 68.78 204.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.72 204.25 Td ($181 ) Tj ET Q q 0 0 0 rg BT 108.22 204.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 137.11 204.25 Td ( ) Tj ET Q q 0 0 0 rg BT 139.61 204.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 149.89 204.25 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 169.89 204.25 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 180.25 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 180.25 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 44.66 180.25 Td ($75 ) Tj ET Q q 0 0 0 rg BT 61.65 180.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 90.54 180.25 Td ( ) Tj ET Q q 0 0 0 rg BT 92.53 180.25 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 117.30 180.25 Td (char) Tj ET Q q 0 0 0 rg BT 134.33 180.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 145.75 180.25 Td (was ) Tj ET Q q 0 0 0 rg BT 163.29 180.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 209.15 180.25 Td (and ) Tj ET Q q 0 0 0 rg BT 225.57 180.25 Td (attributed ) Tj ET Q q 0 0 0 rg BT 265.88 180.25 Td (to ) Tj ET Q q 0 0 0 rg BT 275.65 180.25 Td (noncontrolling ) Tj ET Q q 0 0 0 rg BT 336.52 180.25 Td (interest ) Tj ET Q q 0 0 0 rg BT 367.94 180.25 Td (after ) Tj ET Q q 0 0 0 rg BT 388.25 180.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 411.36 180.25 Td (declined ) Tj ET Q q 0 0 0 rg BT 447.22 180.25 Td (to ) Tj ET Q q 0 0 0 rg BT 456.99 180.25 Td (exercise ) Tj ET Q q 0 0 0 rg BT 491.73 180.25 Td (its ) Tj ET Q q 0 0 0 rg BT 503.17 180.25 Td (option ) Tj ET Q q 0 0 0 rg BT 530.71 180.25 Td (to ) Tj ET Q q 0 0 0 rg BT 540.48 180.25 Td (purchase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 168.25 Td (F-Star ) Tj ET Q q 0 0 0 rg BT 62.67 168.25 Td (Alpha ) Tj ET Q q 0 0 0 rg BT 89.25 168.25 Td (in ) Tj ET Q q 0 0 0 rg BT 99.16 168.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 123.33 168.25 Td (A) Tj ET Q q 0 0 0 rg BT 130.00 168.25 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 132.14 168.25 Td ($160 ) Tj ET Q q 0 0 0 rg BT 154.28 168.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 183.17 168.25 Td ( ) Tj ET Q q 0 0 0 rg BT 185.31 168.25 Td (IPRD ) Tj ET Q q 0 0 0 rg BT 210.24 168.25 Td (impairment ) Tj ET Q q 0 0 0 rg BT 258.48 168.25 Td (char) Tj ET Q q 0 0 0 rg BT 275.50 168.25 Td (ge ) Tj ET Q q 0 0 0 rg BT 287.08 168.25 Td (was ) Tj ET Q q 0 0 0 rg BT 304.77 168.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 350.78 168.25 Td (for ) Tj ET Q q 0 0 0 rg BT 364.58 168.25 Td (BMS-986020 ) Tj ET Q q 0 0 0 rg BT 421.17 168.25 Td (\(LP) Tj ET Q q 0 0 0 rg BT 435.25 168.25 Td (A1 ) Tj ET Q q 0 0 0 rg BT 449.14 168.25 Td (Antagonist\) ) Tj ET Q q 0 0 0 rg BT 498.50 168.25 Td (which ) Tj ET Q q 0 0 0 rg BT 525.08 168.25 Td (was ) Tj ET Q q 0 0 0 rg BT 542.77 168.25 Td (in ) Tj ET Q q 0 0 0 rg BT 552.69 168.25 Td (Phase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 156.25 Td (II ) Tj ET Q q 0 0 0 rg BT 45.19 156.25 Td (development ) Tj ET Q q 0 0 0 rg BT 99.37 156.25 Td (for ) Tj ET Q q 0 0 0 rg BT 113.56 156.25 Td (treatment ) Tj ET Q q 0 0 0 rg BT 153.85 156.25 Td (of ) Tj ET Q q 0 0 0 rg BT 164.71 156.25 Td (IPF ) Tj ET Q q 0 0 0 rg BT 181.69 156.25 Td (in ) Tj ET Q q 0 0 0 rg BT 192.00 156.25 Td (2015. ) Tj ET Q q 0 0 0 rg BT 216.84 156.25 Td (The ) Tj ET Q q 0 0 0 rg BT 234.92 156.25 Td (full ) Tj ET Q q 0 0 0 rg BT 251.33 156.25 Td (write-of) Tj ET Q q 0 0 0 rg BT 283.36 156.25 Td (f ) Tj ET Q q 0 0 0 rg BT 289.22 156.25 Td (was ) Tj ET Q q 0 0 0 rg BT 307.30 156.25 Td (required ) Tj ET Q q 0 0 0 rg BT 343.15 156.25 Td (after ) Tj ET Q q 0 0 0 rg BT 363.99 156.25 Td (considering ) Tj ET Q q 0 0 0 rg BT 413.18 156.25 Td (the ) Tj ET Q q 0 0 0 rg BT 427.92 156.25 Td (occurrence ) Tj ET Q q 0 0 0 rg BT 474.30 156.25 Td (of ) Tj ET Q q 0 0 0 rg BT 485.16 156.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 514.89 156.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 547.96 156.25 Td (events, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 144.25 Td (voluntary ) Tj ET Q q 0 0 0 rg BT 77.14 144.25 Td (suspension ) Tj ET Q q 0 0 0 rg BT 123.85 144.25 Td (of ) Tj ET Q q 0 0 0 rg BT 135.00 144.25 Td (the ) Tj ET Q q 0 0 0 rg BT 150.04 144.25 Td (study ) Tj ET Q q 0 0 0 rg BT 174.53 144.25 Td (and ) Tj ET Q q 0 0 0 rg BT 191.79 144.25 Td (an ) Tj ET Q q 0 0 0 rg BT 204.04 144.25 Td (internal ) Tj ET Q q 0 0 0 rg BT 237.40 144.25 Td (assessment ) Tj ET Q q 0 0 0 rg BT 284.66 144.25 Td (indicating ) Tj ET Q q 0 0 0 rg BT 327.47 144.25 Td (a ) Tj ET Q q 0 0 0 rg BT 334.73 144.25 Td (significantly ) Tj ET Q q 0 0 0 rg BT 387.54 144.25 Td (lower ) Tj ET Q q 0 0 0 rg BT 413.12 144.25 Td (likelihood ) Tj ET Q q 0 0 0 rg BT 456.49 144.25 Td (of ) Tj ET Q q 0 0 0 rg BT 467.64 144.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 511.56 144.25 Td (and ) Tj ET Q q 0 0 0 rg BT 528.81 144.25 Td (commercial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 132.25 Td (success. ) Tj ET Q q 0 0 0 rg BT 70.99 132.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 94.61 132.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 131.54 132.25 Td (BMS-986020 ) Tj ET Q q 0 0 0 rg BT 188.49 132.25 Td (with ) Tj ET Q q 0 0 0 rg BT 208.77 132.25 Td (its ) Tj ET Q q 0 0 0 rg BT 220.72 132.25 Td (acquisition ) Tj ET Q q 0 0 0 rg BT 267.10 132.25 Td (of ) Tj ET Q q 0 0 0 rg BT 277.38 132.25 Td (Amira ) Tj ET Q q 0 0 0 rg BT 305.42 132.25 Td (Pharmaceuticals, ) Tj ET Q q 0 0 0 rg BT 375.95 132.25 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 393.72 132.25 Td (in ) Tj ET Q q 0 0 0 rg BT 404.00 132.25 Td (201) Tj ET Q q 0 0 0 rg BT 418.63 132.25 Td (1.) 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/GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 355.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 325.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 325.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 325.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 325.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 325.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 325.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 325.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 325.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 325.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 325.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 325.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 325.75 29.00 -15.00 re f /GS0 gs 0.8 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1 rg /GS0 gs 387.50 295.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 295.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 295.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 295.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 265.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 265.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 265.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 265.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 265.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 265.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 265.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 265.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 265.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 265.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 235.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 235.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 235.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 235.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 235.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 235.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 235.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 235.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 235.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 235.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 205.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 205.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 205.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 205.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 205.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 205.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 205.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 205.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 205.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 205.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 175.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 175.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 175.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 175.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 175.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 175.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 175.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 175.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 175.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 175.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 145.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 145.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 145.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 145.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 145.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 145.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 145.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 145.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 145.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 145.75 56.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 115.75 161.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 197.50 115.75 31.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 228.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 232.50 115.75 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 270.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 274.50 115.75 47.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 321.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 325.50 115.75 58.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 383.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 387.50 115.75 42.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 115.75 29.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 462.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 466.50 115.75 50.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 516.50 115.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 520.50 115.75 56.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 499.75 m 228.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 228.5 499.75 m 232.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 499.75 m 270.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 499.75 m 462.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 462.5 499.75 m 466.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 499.75 m 516.5 499.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 475.75 m 228.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 475.75 m 270.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 475.75 m 321.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 475.75 m 429.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 475.75 m 462.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 475.75 m 516.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 475.75 m 576.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 475.75 m 383.5 475.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 370.75 m 228.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 370.75 m 270.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 370.75 m 321.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 370.75 m 429.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 370.75 m 462.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 370.75 m 516.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 370.75 m 576.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 370.75 m 383.5 370.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 265.75 m 228.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 265.75 m 270.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 265.75 m 321.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 265.75 m 429.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 265.75 m 462.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 265.75 m 516.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 265.75 m 576.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 265.75 m 383.5 265.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 235.75 m 228.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 235.75 m 270.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 235.75 m 321.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 235.75 m 383.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 235.75 m 429.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 235.75 m 462.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 235.75 m 516.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 235.75 m 576.5 235.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 115.75 m 228.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 115.75 m 270.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 115.75 m 321.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 115.75 m 429.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 115.75 m 462.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 115.75 m 516.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 115.75 m 576.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 101.75 m 228.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 197.5 99.75 m 228.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 101.75 m 270.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 232.5 99.75 m 270.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 101.75 m 321.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 274.5 99.75 m 321.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 115.75 m 383.5 115.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 101.75 m 383.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 325.5 99.75 m 383.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 101.75 m 429.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 387.5 99.75 m 429.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 101.75 m 462.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 99.75 m 462.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 101.75 m 516.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 466.5 99.75 m 516.5 99.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 101.75 m 576.5 101.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 520.5 99.75 m 576.5 99.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 504.00 Td ( ) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 208.80 503.87 Td (Common Stock) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 281.55 502.37 Td (Capital in  ) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 286.85 494.87 Td (Excess) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 277.75 487.37 Td (of Par) Tj ET Q q 0 0 0 rg BT 297.40 487.37 Td ( ) Tj ET Q q 0 0 0 rg BT 299.14 487.37 Td (V) Tj ET Q q 0 0 0 rg BT 303.87 487.37 Td (alue) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 284.45 479.87 Td (of Stock) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 332.75 502.37 Td (Accumulated) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 344.45 494.87 Td (Other) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 329.05 487.37 Td (Compr) Tj ET Q q 0 0 0 rg BT 351.90 487.37 Td (ehensive) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 346.70 479.87 Td (Loss) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 393.60 487.37 Td (Retained) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 393.40 479.87 Td (Earnings) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 450.15 503.87 Td (T) Tj ET Q q 0 0 0 rg BT 454.87 503.87 Td (r) Tj ET Q q 0 0 0 rg BT 457.86 503.87 Td (easury Stock) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 523.85 487.37 Td (Noncontr) Tj ET Q q 0 0 0 rg BT 554.13 487.37 Td (olling) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 535.55 479.87 Td (Inter) Tj ET Q q 0 0 0 rg BT 551.66 479.87 Td (est) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 480.00 Td (Dollars and Shares in Millions) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 201.70 479.87 Td (Shar) Tj ET Q q 0 0 0 rg BT 217.05 479.87 Td (es) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 235.30 479.87 Td (Par) Tj ET Q q 0 0 0 rg BT 246.89 479.87 Td ( ) Tj ET Q q 0 0 0 rg BT 248.63 479.87 Td (V) Tj ET Q q 0 0 0 rg BT 253.64 479.87 Td (alue) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 436.70 479.87 Td (Shar) Tj ET Q q 0 0 0 rg BT 452.05 479.87 Td (es) Tj ET Q BT /F2 7.50 Tf ET q 0 0 0 rg BT 483.70 479.87 Td (Cost        ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 466.32 Td (Balance at January 1, 2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.10 465.42 Td (2,208) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 235.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.65 465.42 Td (221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 277.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 465.42 Td (1,507) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.80 465.47 Td (\(2,425) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 465.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.10 465.42 Td (32,541) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.60 465.42 Td (547) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 465.47 Td (\(16,992) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 465.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.00 465.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 465.42 Td (131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 451.32 Td (Net earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.10 450.42 Td (1,565) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 450.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 450.42 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 436.32 Td (Other comprehensive loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.30 435.47 Td (\(43) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 435.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 435.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 421.32 Td (Cash dividends) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 420.47 Td (\(2,493) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 420.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 420.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 406.32 Td (Stock compensation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 405.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 405.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 304.30 405.47 Td (\(48) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 317.65 405.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 405.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 405.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.30 405.47 Td (\(8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.65 405.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.65 405.42 Td (431) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 405.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 391.32 Td (Debt conversion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 390.42 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 390.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 376.32 Td (Distributions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 375.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 375.42 Td (\(57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 375.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 361.32 Td (Balance at December 31, 2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.10 360.42 Td (2,208) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.65 360.42 Td (221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 360.42 Td (1,459) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.80 360.47 Td (\(2,468) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 360.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.10 360.42 Td (31,613) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.60 360.42 Td (539) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 360.47 Td (\(16,559) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 360.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 360.42 Td (158) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 346.32 Td (Net earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.10 345.42 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 345.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 345.42 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 331.32 Td (Other comprehensive loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.30 330.47 Td (\(35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 330.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 330.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 316.32 Td (Cash dividends) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 315.47 Td (\(2,557) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 315.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 315.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 301.32 Td (Stock repurchase program) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 300.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 300.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 300.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 300.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 453.65 300.42 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.30 300.47 Td (\(231) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 300.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 300.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 286.32 Td (Stock compensation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 285.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 285.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.65 285.42 Td (266) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 285.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 285.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.30 285.47 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.65 285.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 285.42 Td (1) Tj ET Q q 0 0 0 rg BT 507.65 285.42 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 285.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 271.32 Td (Distributions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 270.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 270.42 Td (\(38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 270.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 256.32 Td (Balance at December 31, 2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.10 255.42 Td (2,208) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.65 255.42 Td (221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 255.42 Td (1,725) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.80 255.47 Td (\(2,503) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 255.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.10 255.42 Td (33,513) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.60 255.42 Td (536) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 255.47 Td (\(16,779) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 255.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 255.42 Td (170) Tj ET Q BT /F1 9.50 Tf ET q 0 0 0 rg BT 39.00 241.66 Td (Accounting change - cumulative ef) Tj ET Q q 0 0 0 rg BT 172.31 241.66 Td (fect) Tj ET Q BT /F1 9.50 Tf ET BT /F1 6.17 Tf ET q 0 0 0 rg BT 186.54 245.97 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.30 240.47 Td (\(787) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 240.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 240.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 226.32 Td (Adjusted balance at January 1, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.10 225.42 Td (2,208) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.65 225.42 Td (221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 225.42 Td (1,725) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.80 225.47 Td (\(2,503) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 225.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.10 225.42 Td (32,726) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.60 225.42 Td (536) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 225.47 Td (\(16,779) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 225.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 225.42 Td (170) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 211.32 Td (Net earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.10 210.42 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 210.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 210.42 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 196.32 Td (Other comprehensive income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.65 195.42 Td (214) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 195.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 181.32 Td (Cash dividends) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.80 180.47 Td (\(2,573) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.65 180.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 180.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 166.32 Td (Stock repurchase program) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 165.42 Td (44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.80 165.47 Td (\(2,477) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 165.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 165.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 151.32 Td (Stock compensation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 150.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 150.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.65 150.42 Td (173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 150.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 150.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.30 150.47 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 458.65 150.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 150.42 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 150.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 136.32 Td (V) Tj ET Q q 0 0 0 rg BT 45.67 136.32 Td (ariable interest entity) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 135.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 135.42 Td (\(59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 135.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 121.32 Td (Distributions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.60 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.65 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.65 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 369.65 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.60 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.65 120.42 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 120.42 Td (\(32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 120.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 106.32 Td (Balance at December 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.10 105.42 Td (2,208) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 235.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 251.65 105.42 Td (221) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 277.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 295.15 105.42 Td (1,898) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 328.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 353.80 105.47 Td (\(2,289) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.65 105.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 398.10 105.42 Td (31,160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.60 105.42 Td (575) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.80 105.47 Td (\(19,249) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 105.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 523.00 105.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 105.42 Td (106) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 36.00 89.25 Td (\(a\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 46.88 89.25 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 49.38 89.25 Td (Refer ) Tj ET Q q 0 0 0 rg BT 69.14 89.25 Td (to ) Tj ET Q q 0 0 0 rg BT 77.37 89.25 Td ("—Note ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 106.18 89.25 Td (1) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 110.18 89.25 Td (. ) Tj ET Q q 0 0 0 rg BT 113.74 89.25 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 153.07 89.25 Td (Policies ) Tj ET Q q 0 0 0 rg BT 180.40 89.25 Td (and ) Tj ET Q q 0 0 0 rg BT 193.95 89.25 Td (Recently ) Tj ET Q q 0 0 0 rg BT 224.38 89.25 Td (Issued ) Tj ET Q q 0 0 0 rg BT 246.38 89.25 Td (Accounting ) Tj ET Q q 0 0 0 rg BT 285.71 89.25 Td (Standards" ) Tj ET Q q 0 0 0 rg BT 322.52 89.25 Td (for ) Tj ET Q q 0 0 0 rg BT 333.85 89.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 367.84 89.25 Td (information.) Tj ET Q endstream endobj 185 0 obj <> endobj 186 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (92) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.17 749.10 Td (has ) Tj ET Q q 0 0 0 rg BT 74.54 749.10 Td (a ) Tj ET Q q 0 0 0 rg BT 81.03 749.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 104.18 749.10 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 149.53 749.10 Td (program ) Tj ET Q q 0 0 0 rg BT 185.45 749.10 Td (authorized ) Tj ET Q q 0 0 0 rg BT 229.70 749.10 Td (by ) Tj ET Q q 0 0 0 rg BT 241.74 749.10 Td (its ) Tj ET Q q 0 0 0 rg BT 253.24 749.10 Td (Board ) Tj ET Q q 0 0 0 rg BT 279.72 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 290.10 749.10 Td (Directors ) Tj ET Q q 0 0 0 rg BT 329.35 749.10 Td (allowing ) Tj ET Q q 0 0 0 rg BT 366.39 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 380.09 749.10 Td (repurchases ) Tj ET Q q 0 0 0 rg BT 429.33 749.10 Td (in ) Tj ET Q q 0 0 0 rg BT 439.16 749.10 Td (the ) Tj ET Q q 0 0 0 rg BT 453.42 749.10 Td (open ) Tj ET Q q 0 0 0 rg BT 474.90 749.10 Td (market ) Tj ET Q q 0 0 0 rg BT 504.71 749.10 Td (or ) Tj ET Q q 0 0 0 rg BT 515.09 749.10 Td (through ) Tj ET Q q 0 0 0 rg BT 548.24 749.10 Td (private ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (transactions, ) Tj ET Q q 0 0 0 rg BT 87.94 737.10 Td (including ) Tj ET Q q 0 0 0 rg BT 127.38 737.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 150.16 737.10 Td (established ) Tj ET Q q 0 0 0 rg BT 196.27 737.10 Td (in ) Tj ET Q q 0 0 0 rg BT 205.72 737.10 Td (accordance ) Tj ET Q q 0 0 0 rg BT 252.35 737.10 Td (with ) Tj ET Q q 0 0 0 rg BT 271.80 737.10 Td (Rule ) Tj ET Q q 0 0 0 rg BT 292.36 737.10 Td (10b5-1 ) Tj ET Q q 0 0 0 rg BT 322.36 737.10 Td (under ) Tj ET Q q 0 0 0 rg BT 346.81 737.10 Td (the ) Tj ET Q q 0 0 0 rg BT 360.69 737.10 Td (Securities ) Tj ET Q q 0 0 0 rg BT 401.80 737.10 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 442.53 737.10 Td (Act ) Tj ET Q q 0 0 0 rg BT 458.64 737.10 Td (of ) Tj ET Q q 0 0 0 rg BT 468.64 737.10 Td (1934. ) Tj ET Q q 0 0 0 rg BT 492.69 737.10 Td (The ) Tj ET Q q 0 0 0 rg BT 509.91 737.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 532.69 737.10 Td (repurchase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (program ) Tj ET Q q 0 0 0 rg BT 72.29 725.10 Td (does ) Tj ET Q q 0 0 0 rg BT 93.03 725.10 Td (not ) Tj ET Q q 0 0 0 rg BT 108.21 725.10 Td (have ) Tj ET Q q 0 0 0 rg BT 129.50 725.10 Td (an ) Tj ET Q q 0 0 0 rg BT 141.35 725.10 Td (expiration ) Tj ET Q q 0 0 0 rg BT 184.30 725.10 Td (date ) Tj ET Q q 0 0 0 rg BT 203.37 725.10 Td (and ) Tj ET Q q 0 0 0 rg BT 220.21 725.10 Td (may ) Tj ET Q q 0 0 0 rg BT 239.84 725.10 Td (be ) Tj ET Q q 0 0 0 rg BT 251.69 725.10 Td (suspended ) Tj ET Q q 0 0 0 rg BT 295.76 725.10 Td (or ) Tj ET Q q 0 0 0 rg BT 306.50 725.10 Td (discontinued ) Tj ET Q q 0 0 0 rg BT 360.01 725.10 Td (at ) Tj ET Q q 0 0 0 rg BT 369.64 725.10 Td (any ) Tj ET Q q 0 0 0 rg BT 386.49 725.10 Td (time. ) Tj ET Q q 0 0 0 rg BT 408.99 725.10 Td (T) Tj ET Q q 0 0 0 rg BT 414.75 725.10 Td (reasury ) Tj ET Q q 0 0 0 rg BT 446.59 725.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 470.11 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 479.19 725.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 525.46 725.10 Td (at ) Tj ET Q q 0 0 0 rg BT 535.09 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 549.71 725.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 568.23 725.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (reacquire ) Tj ET Q q 0 0 0 rg BT 75.88 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 90.79 713.10 Td (shares. ) Tj ET Q q 0 0 0 rg BT 120.97 713.10 Td (Shares ) Tj ET Q q 0 0 0 rg BT 150.32 713.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 178.01 713.10 Td (from ) Tj ET Q q 0 0 0 rg BT 200.14 713.10 Td (treasury ) Tj ET Q q 0 0 0 rg BT 235.04 713.10 Td (are ) Tj ET Q q 0 0 0 rg BT 249.94 713.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 296.49 713.10 Td (utilizing ) Tj ET Q q 0 0 0 rg BT 332.51 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 347.42 713.10 Td (first-in ) Tj ET Q q 0 0 0 rg BT 377.32 713.10 Td (first-out ) Tj ET Q q 0 0 0 rg BT 412.23 713.10 Td (method. ) Tj ET Q q 0 0 0 rg BT 447.42 713.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 471.23 713.10 Td (repurchased ) Tj ET Q q 0 0 0 rg BT 522.23 713.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 549.91 713.10 Td (during ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (2017 ) Tj ET Q q 0 0 0 rg BT 58.50 701.10 Td (through ) Tj ET Q q 0 0 0 rg BT 92.11 701.10 Td (Rule ) Tj ET Q q 0 0 0 rg BT 113.50 701.10 Td (10b5-1, ) Tj ET Q q 0 0 0 rg BT 146.83 701.10 Td (open ) Tj ET Q q 0 0 0 rg BT 168.76 701.10 Td (market ) Tj ET Q q 0 0 0 rg BT 199.03 701.10 Td (purchases ) Tj ET Q q 0 0 0 rg BT 240.96 701.10 Td (and ) Tj ET Q q 0 0 0 rg BT 257.89 701.10 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 305.35 701.10 Td (share ) Tj ET Q q 0 0 0 rg BT 328.95 701.10 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 374.75 701.10 Td (agreements.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 59.11 677.10 Td (completed ) Tj ET Q q 0 0 0 rg BT 102.74 677.10 Td (accelerated ) Tj ET Q q 0 0 0 rg BT 149.68 677.10 Td (share ) Tj ET Q q 0 0 0 rg BT 172.77 677.10 Td (repurchase ) Tj ET Q q 0 0 0 rg BT 218.06 677.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 265.58 677.10 Td (that ) Tj ET Q q 0 0 0 rg BT 282.56 677.10 Td (repurchased ) Tj ET Q q 0 0 0 rg BT 332.85 677.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.59 677.10 Td (36.5 ) Tj ET Q q 0 0 0 rg BT 412.07 677.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 440.97 677.10 Td ( ) Tj ET Q q 0 0 0 rg BT 442.95 677.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 469.93 677.10 Td (of ) Tj ET Q q 0 0 0 rg BT 480.24 677.10 Td (the ) Tj ET Q q 0 0 0 rg BT 494.44 677.10 Td (Company's ) Tj ET Q q 0 0 0 rg BT 541.01 677.10 Td (common ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 59.61 665.10 Td (for ) Tj ET Q q 0 0 0 rg BT 73.77 665.10 Td (an ) Tj ET Q q 0 0 0 rg BT 85.71 665.10 Td (aggregate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 127.07 665.10 Td ($2 ) Tj ET Q q 0 0 0 rg BT 139.57 665.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 165.68 665.10 Td ( ) Tj ET Q q 0 0 0 rg BT 168.18 665.10 Td (in ) Tj ET Q q 0 0 0 rg BT 178.46 665.10 Td (2017. ) Tj ET Q q 0 0 0 rg BT 203.28 665.10 Td (The ) Tj ET Q q 0 0 0 rg BT 221.33 665.10 Td (agreements ) Tj ET Q q 0 0 0 rg BT 269.36 665.10 Td (were ) Tj ET Q q 0 0 0 rg BT 291.29 665.10 Td (funded ) Tj ET Q q 0 0 0 rg BT 321.56 665.10 Td (through ) Tj ET Q q 0 0 0 rg BT 355.17 665.10 Td (a ) Tj ET Q q 0 0 0 rg BT 362.10 665.10 Td (combination ) Tj ET Q q 0 0 0 rg BT 414.59 665.10 Td (of ) Tj ET Q q 0 0 0 rg BT 425.42 665.10 Td (debt ) Tj ET Q q 0 0 0 rg BT 445.14 665.10 Td (and ) Tj ET Q q 0 0 0 rg BT 462.08 665.10 Td (cash. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 641.10 Td (components ) Tj ET Q q 0 0 0 rg BT 104.87 641.10 Td (of ) Tj ET Q q 0 0 0 rg BT 115.70 641.10 Td (other ) Tj ET Q q 0 0 0 rg BT 138.75 641.10 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 201.78 641.10 Td (income/\(loss\) ) Tj ET Q q 0 0 0 rg BT 258.71 641.10 Td (were ) Tj ET Q q 0 0 0 rg BT 280.64 641.10 Td (as ) Tj ET Q q 0 0 0 rg BT 291.47 641.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 585.60 160.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 195.50 585.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 237.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 276.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 280.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 319.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 323.50 585.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 585.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 489.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 532.50 585.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 536.50 585.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 35.50 555.60 160.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 195.50 555.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 233.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 237.50 555.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 276.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 280.50 555.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 319.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 323.50 555.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 365.50 555.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 404.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 555.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 447.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 451.50 555.60 38.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 489.50 555.60 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 555.60 39.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 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/GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 280.5 359.6 m 319.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 323.5 375.6 m 361.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 323.5 361.6 m 361.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 323.5 359.6 m 361.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 375.6 m 404.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 361.6 m 404.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 365.5 359.6 m 404.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 408.5 375.6 m 447.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 408.5 361.6 m 447.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 408.5 359.6 m 447.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 375.6 m 489.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 361.6 m 489.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 451.5 359.6 m 489.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 493.5 375.6 m 532.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 493.5 361.6 m 532.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 493.5 359.6 m 532.5 359.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 536.5 375.6 m 575.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 536.5 361.6 m 575.5 361.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 536.5 359.6 m 575.5 359.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 619.85 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 340.20 619.83 Td (Y) Tj ET Q q 0 0 0 rg BT 345.53 619.83 Td (ear) Tj ET Q q 0 0 0 rg BT 356.12 619.83 Td ( Ended December) Tj ET Q q 0 0 0 rg BT 416.85 619.83 Td ( 31,) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 249.00 604.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 377.00 604.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 505.00 604.83 Td (2015) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.00 589.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 202.70 589.83 Td (Pr) Tj ET Q q 0 0 0 rg BT 211.07 589.83 Td (etax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 250.15 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 255.12 589.83 Td (ax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 283.20 589.83 Td (After) Tj ET Q q 0 0 0 rg BT 301.33 589.83 Td ( ) Tj ET Q q 0 0 0 rg BT 303.19 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 308.09 589.83 Td (ax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 330.70 589.83 Td (Pr) Tj ET Q q 0 0 0 rg BT 339.07 589.83 Td (etax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 378.15 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 383.12 589.83 Td (ax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 411.20 589.83 Td (After) Tj ET Q q 0 0 0 rg BT 429.33 589.83 Td ( ) Tj ET Q q 0 0 0 rg BT 431.19 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 436.09 589.83 Td (ax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.70 589.83 Td (Pr) Tj ET Q q 0 0 0 rg BT 467.07 589.83 Td (etax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 506.15 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 511.12 589.83 Td (ax) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 539.20 589.83 Td (After) Tj ET Q q 0 0 0 rg BT 557.26 589.83 Td ( ) Tj ET Q q 0 0 0 rg BT 559.12 589.83 Td (T) Tj ET Q q 0 0 0 rg BT 563.72 589.83 Td (ax) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 574.96 Td (Derivatives qualifying as cash flow hedges:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 562.21 Td (Unrealized gains/\(losses\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 198.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 211.30 560.27 Td (\(101) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.65 560.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 240.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.65 560.27 Td (33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 283.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.30 560.32 Td (\(68) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.65 560.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 326.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 349.30 560.32 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 560.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 368.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.65 560.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 435.30 560.32 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 560.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.65 560.27 Td (59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 560.32 Td (\(22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 560.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 539.00 560.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 560.27 Td (37) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 547.21 Td (Reclassified to net earnings) Tj ET Q BT /F1 8.50 Tf ET BT /F1 5.52 Tf ET q 0 0 0 rg BT 149.71 551.06 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.65 545.27 Td (19) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.30 545.27 Td (\(8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.65 545.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 545.27 Td (1) Tj ET Q q 0 0 0 rg BT 310.65 545.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 545.27 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 545.32 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 545.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.65 545.27 Td (9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.30 545.32 Td (\(130) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 545.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 545.27 Td (42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 545.27 Td (\(88) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 545.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 532.21 Td (Derivatives qualifying as cash flow hedges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 216.30 530.27 Td (\(82) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.65 530.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.65 530.27 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 302.30 530.32 Td (\(57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.65 530.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.65 530.27 Td (7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 530.32 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 530.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 438.65 530.27 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.30 530.32 Td (\(71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 530.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 530.27 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 530.27 Td (\(51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 530.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 514.96 Td (Pension and postretirement benefits:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 502.21 Td (Actuarial gains/\(losses\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.65 500.27 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.65 500.27 Td (1) Tj ET Q q 0 0 0 rg BT 267.65 500.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 500.27 Td (58) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 339.30 500.32 Td (\(126) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 500.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 500.32 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 500.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 425.30 500.32 Td (\(129) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 500.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.30 500.32 Td (\(88) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 500.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 500.27 Td (27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 500.27 Td (\(61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 500.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 487.21 Td (Amortization) Tj ET Q BT /F1 8.50 Tf ET BT /F1 5.52 Tf ET q 0 0 0 rg BT 101.32 491.06 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.65 485.27 Td (77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.30 485.27 Td (\(31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.65 485.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 485.27 Td (46) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 485.27 Td (78) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.30 485.32 Td (\(25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 485.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.65 485.27 Td (53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.65 485.27 Td (85) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 485.32 Td (\(28) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 485.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 561.65 485.27 Td (57) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 472.21 Td (Settlements) Tj ET Q BT /F1 8.50 Tf ET BT /F1 5.52 Tf ET q 0 0 0 rg BT 95.66 476.06 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.65 470.27 Td (167) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.30 470.27 Td (\(57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.65 470.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.65 470.27 Td (1) Tj ET Q q 0 0 0 rg BT 305.65 470.27 Td (10) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 470.27 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.30 470.32 Td (\(32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 470.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.65 470.27 Td (59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.65 470.27 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 470.32 Td (\(55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 470.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 470.27 Td (105) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 457.21 Td (Pension and postretirement benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.65 455.27 Td (291) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.30 455.27 Td (\(77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.65 455.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.65 455.27 Td (214) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 455.27 Td (43) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.30 455.32 Td (\(60) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 455.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.30 455.32 Td (\(17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 455.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.65 455.27 Td (157) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 455.32 Td (\(56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 455.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 556.65 455.27 Td (101) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 442.21 Td (A) Tj ET Q q 0 0 0 rg BT 43.82 442.21 Td (vailable-for) Tj ET Q q 0 0 0 rg BT 83.07 442.21 Td (-sale securities:) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 427.21 Td (Unrealized gains/\(losses\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.65 425.27 Td (38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.65 425.27 Td (6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 425.27 Td (44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.30 425.32 Td (\(12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 425.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 425.32 Td (\(1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 425.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.30 425.32 Td (\(13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 425.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.30 425.32 Td (\(71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 425.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 425.27 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 425.27 Td (\(57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 425.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 56.00 412.21 Td (Realized \(gains\)/losses) Tj ET Q BT /F1 8.50 Tf ET BT /F1 5.52 Tf ET q 0 0 0 rg BT 134.13 416.06 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 221.30 410.27 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.65 410.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.65 410.27 Td (2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.30 410.32 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.65 410.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 410.27 Td (29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 390.65 410.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.65 410.27 Td (29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.65 410.27 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 410.27 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 566.65 410.27 Td (3) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 394.96 Td (A) Tj ET Q q 0 0 0 rg BT 43.82 394.96 Td (vailable-for) Tj ET Q q 0 0 0 rg BT 83.07 394.96 Td (-sale securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 219.65 395.27 Td (31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.65 395.27 Td (8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 395.27 Td (39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 395.27 Td (17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 395.32 Td (\(1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 395.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.65 395.27 Td (16) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.30 395.32 Td (\(68) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 395.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 518.65 395.27 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 395.27 Td (\(54) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 395.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 382.21 Td (Foreign currency translation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 216.30 380.27 Td (\(20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.65 380.27 Td (38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 305.65 380.27 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.30 380.32 Td (\(33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 392.30 380.32 Td (\(5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.30 380.32 Td (\(38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.30 380.32 Td (\(17) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 380.32 Td (\(22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 380.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 380.27 Td (\(39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 380.27 Td (\)) Tj ET Q BT /F1 8.50 Tf ET q 0 0 0 rg BT 38.00 364.96 Td (T) Tj ET Q q 0 0 0 rg BT 42.60 364.96 Td (otal Other Comprehensive Income/\(Loss\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 198.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 214.65 365.27 Td (220) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 240.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 264.30 365.27 Td (\(6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.65 365.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 283.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.65 365.27 Td (214) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 326.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 365.27 Td (34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 368.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 387.30 365.32 Td (\(69) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.65 365.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 430.30 365.32 Td (\(35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.65 365.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.65 365.27 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.30 365.32 Td (\(44) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 528.65 365.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 539.00 365.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 558.30 365.27 Td (\(43) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 571.65 365.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 344.30 Td (\(a\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 344.30 Td (Included ) Tj ET Q q 0 0 0 rg BT 91.34 344.30 Td (in ) Tj ET Q q 0 0 0 rg BT 99.56 344.30 Td (cost ) Tj ET Q q 0 0 0 rg BT 114.45 344.30 Td (of ) Tj ET Q q 0 0 0 rg BT 123.11 344.30 Td (products ) Tj ET Q q 0 0 0 rg BT 152.66 344.30 Td (sold) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 334.70 Td (\(b\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 334.70 Td (Included ) Tj ET Q q 0 0 0 rg BT 91.34 334.70 Td (in ) Tj ET Q q 0 0 0 rg BT 99.56 334.70 Td (cost ) Tj ET Q q 0 0 0 rg BT 114.45 334.70 Td (of ) Tj ET Q q 0 0 0 rg BT 123.11 334.70 Td (products ) Tj ET Q q 0 0 0 rg BT 152.66 334.70 Td (sold, ) Tj ET Q q 0 0 0 rg BT 170.00 334.70 Td (research ) Tj ET Q q 0 0 0 rg BT 198.64 334.70 Td (and ) Tj ET Q q 0 0 0 rg BT 212.19 334.70 Td (development, ) Tj ET Q q 0 0 0 rg BT 257.51 334.70 Td (and ) Tj ET Q q 0 0 0 rg BT 271.06 334.70 Td (marketing, ) Tj ET Q q 0 0 0 rg BT 307.50 334.70 Td (selling ) Tj ET Q q 0 0 0 rg BT 330.83 334.70 Td (and ) Tj ET Q q 0 0 0 rg BT 344.38 334.70 Td (administrative ) Tj ET Q q 0 0 0 rg BT 392.15 334.70 Td (expenses) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 38.85 325.10 Td (\(c\) ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.35 325.10 Td (Included ) Tj ET Q q 0 0 0 rg BT 91.34 325.10 Td (in ) Tj ET Q q 0 0 0 rg BT 99.56 325.10 Td (other ) Tj ET Q q 0 0 0 rg BT 118.00 325.10 Td (income ) Tj ET Q q 0 0 0 rg BT 143.55 325.10 Td (\(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 304.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 304.10 Td (accumulated ) Tj ET Q q 0 0 0 rg BT 107.07 304.10 Td (balances ) Tj ET Q q 0 0 0 rg BT 144.00 304.10 Td (related ) Tj ET Q q 0 0 0 rg BT 173.70 304.10 Td (to ) Tj ET Q q 0 0 0 rg BT 183.98 304.10 Td (each ) Tj ET Q q 0 0 0 rg BT 204.79 304.10 Td (component ) Tj ET Q q 0 0 0 rg BT 251.73 304.10 Td (of ) Tj ET Q q 0 0 0 rg BT 262.56 304.10 Td (other ) Tj ET Q q 0 0 0 rg BT 285.60 304.10 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 348.64 304.10 Td (loss, ) Tj ET Q q 0 0 0 rg BT 369.20 304.10 Td (net ) Tj ET Q q 0 0 0 rg BT 383.92 304.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.75 304.10 Td (taxes, ) Tj ET Q q 0 0 0 rg BT 420.29 304.10 Td (were ) Tj ET Q q 0 0 0 rg BT 442.22 304.10 Td (as ) Tj ET Q q 0 0 0 rg BT 453.05 304.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 269.60 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 269.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 269.60 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 269.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 269.60 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 241.60 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 241.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 241.60 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 241.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 241.60 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 213.60 370.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 406.50 213.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 213.60 81.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 491.50 213.60 4.00 -14.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 495.50 213.60 81.00 -14.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 281.6 m 491.5 281.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 491.5 281.6 m 495.5 281.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 281.6 m 576.5 281.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 269.6 m 491.5 269.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 269.6 m 576.5 269.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 269.6 m 491.5 269.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 213.60000000000002 m 491.5 213.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 213.60000000000002 m 576.5 213.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 200.60000000000002 m 491.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 410.5 198.60000000000002 m 491.5 198.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 200.60000000000002 m 576.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 495.5 198.60000000000002 m 576.5 198.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 285.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 469.75 285.68 Td (December) Tj ET Q q 0 0 0 rg BT 504.32 285.68 Td ( 31,) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 273.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 442.50 273.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 527.50 273.68 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 260.17 Td (Derivatives qualifying as cash flow hedges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.00 260.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.30 260.22 Td (\(19) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 260.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 260.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 260.17 Td (38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 246.17 Td (Pension and postretirement benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 246.22 Td (\(1,883) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 246.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 246.17 Td (\(2,097) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 246.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 232.17 Td (A) Tj ET Q q 0 0 0 rg BT 45.85 232.17 Td (vailable-for) Tj ET Q q 0 0 0 rg BT 92.02 232.17 Td (-sale securities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.65 232.17 Td (32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 232.17 Td (\(7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 232.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 218.17 Td (Foreign currency translation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 469.30 218.22 Td (\(419) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 218.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 218.17 Td (\(437) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 218.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 204.17 Td (Accumulated other comprehensive loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.00 204.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.80 204.22 Td (\(2,289) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 204.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 498.00 204.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.80 204.17 Td (\(2,503) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 204.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 174.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 174.10 Td (16) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 174.10 Td (. PENSION ) Tj ET Q q 0 0 0 rg BT 119.89 174.10 Td (AND POSTRETIREMENT) Tj ET Q q 0 0 0 rg BT 238.34 174.10 Td ( BENEFIT) Tj ET Q q 0 0 0 rg BT 284.56 174.10 Td ( PLANS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 157.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 58.94 157.10 Td (sponsors ) Tj ET Q q 0 0 0 rg BT 95.75 157.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 127.55 157.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 157.13 157.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 190.05 157.10 Td (plans, ) Tj ET Q q 0 0 0 rg BT 215.47 157.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 247.27 157.10 Td (contribution ) Tj ET Q q 0 0 0 rg BT 297.96 157.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 320.89 157.10 Td (and ) Tj ET Q q 0 0 0 rg BT 337.14 157.10 Td (termination ) Tj ET Q q 0 0 0 rg BT 385.05 157.10 Td (indemnity ) Tj ET Q q 0 0 0 rg BT 427.41 157.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 450.34 157.10 Td (for ) Tj ET Q q 0 0 0 rg BT 463.81 157.10 Td (regular ) Tj ET Q q 0 0 0 rg BT 493.94 157.10 Td (full-time ) Tj ET Q q 0 0 0 rg BT 530.74 157.10 Td (employees. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 145.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.81 145.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 93.61 145.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 126.85 145.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 157.87 145.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 192.24 145.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 212.71 145.10 Td (is ) Tj ET Q q 0 0 0 rg BT 222.64 145.10 Td (the ) Tj ET Q q 0 0 0 rg BT 238.12 145.10 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 297.48 145.10 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 329.08 145.10 Td (Retirement ) Tj ET Q q 0 0 0 rg BT 376.77 145.10 Td (Income ) Tj ET Q q 0 0 0 rg BT 410.01 145.10 Td (Plan, ) Tj ET Q q 0 0 0 rg BT 433.55 145.10 Td (covering ) Tj ET Q q 0 0 0 rg BT 471.79 145.10 Td (most ) Tj ET Q q 0 0 0 rg BT 494.50 145.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 515.54 145.10 Td (employees ) Tj ET Q q 0 0 0 rg BT 561.56 145.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 133.10 Td (representing ) Tj ET Q q 0 0 0 rg BT 88.23 133.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 148.79 133.10 Td (66%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 167.12 133.10 Td ( ) Tj ET Q q 0 0 0 rg BT 169.92 133.10 Td (of ) Tj ET Q q 0 0 0 rg BT 181.05 133.10 Td (the ) Tj ET Q q 0 0 0 rg BT 196.07 133.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 249.41 133.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 283.32 133.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 303.34 133.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 329.47 133.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.71 133.10 Td (62%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 365.04 133.10 Td ( ) Tj ET Q q 0 0 0 rg BT 367.84 133.10 Td (of ) Tj ET Q q 0 0 0 rg BT 378.98 133.10 Td (the ) Tj ET Q q 0 0 0 rg BT 394.00 133.10 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 443.74 133.10 Td (Future ) Tj ET Q q 0 0 0 rg BT 472.65 133.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 507.11 133.10 Td (related ) Tj ET Q q 0 0 0 rg BT 537.11 133.10 Td (to ) Tj ET Q q 0 0 0 rg BT 547.69 133.10 Td (service ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 121.10 Td (for ) Tj ET Q q 0 0 0 rg BT 50.58 121.10 Td (this ) Tj ET Q q 0 0 0 rg BT 67.94 121.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 88.07 121.10 Td (were ) Tj ET Q q 0 0 0 rg BT 110.42 121.10 Td (eliminated ) Tj ET Q q 0 0 0 rg BT 155.54 121.10 Td (in ) Tj ET Q q 0 0 0 rg BT 166.24 121.10 Td (2009. ) Tj ET Q q 0 0 0 rg BT 191.65 121.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 215.69 121.10 Td (contributes ) Tj ET Q q 0 0 0 rg BT 263.04 121.10 Td (at ) Tj ET Q q 0 0 0 rg BT 273.18 121.10 Td (least ) Tj ET Q q 0 0 0 rg BT 294.42 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 309.55 121.10 Td (minimum ) Tj ET Q q 0 0 0 rg BT 351.36 121.10 Td (amount ) Tj ET Q q 0 0 0 rg BT 384.27 121.10 Td (required ) Tj ET Q q 0 0 0 rg BT 420.50 121.10 Td (by ) Tj ET Q q 0 0 0 rg BT 433.42 121.10 Td (the ) Tj ET Q q 0 0 0 rg BT 448.55 121.10 Td (ERISA. ) Tj ET Q q 0 0 0 rg BT 482.86 121.10 Td (Plan ) Tj ET Q q 0 0 0 rg BT 503.56 121.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 538.13 121.10 Td (are ) Tj ET Q q 0 0 0 rg BT 553.25 121.10 Td (based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 109.10 Td (primarily ) Tj ET Q q 0 0 0 rg BT 75.08 109.10 Td (on ) Tj ET Q q 0 0 0 rg BT 86.95 109.10 Td (the ) Tj ET Q q 0 0 0 rg BT 101.03 109.10 Td (participant’) Tj ET Q q 0 0 0 rg BT 146.57 109.10 Td (s ) Tj ET Q q 0 0 0 rg BT 152.32 109.10 Td (years ) Tj ET Q q 0 0 0 rg BT 175.29 109.10 Td (of ) Tj ET Q q 0 0 0 rg BT 185.49 109.10 Td (credited ) Tj ET Q q 0 0 0 rg BT 219.56 109.10 Td (service ) Tj ET Q q 0 0 0 rg BT 249.74 109.10 Td (and ) Tj ET Q q 0 0 0 rg BT 266.04 109.10 Td (final ) Tj ET Q q 0 0 0 rg BT 286.23 109.10 Td (average ) Tj ET Q q 0 0 0 rg BT 319.19 109.10 Td (compensation. ) Tj ET Q q 0 0 0 rg BT 379.09 109.10 Td (Plan ) Tj ET Q q 0 0 0 rg BT 398.74 109.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 423.94 109.10 Td (consist ) Tj ET Q q 0 0 0 rg BT 453.58 109.10 Td (principally ) Tj ET Q q 0 0 0 rg BT 498.77 109.10 Td (of ) Tj ET Q q 0 0 0 rg BT 508.96 109.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 535.83 109.10 Td (and ) Tj ET Q q 0 0 0 rg BT 552.13 109.10 Td (fixed-) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 97.10 Td (income ) Tj ET Q q 0 0 0 rg BT 67.93 97.10 Td (securities. ) Tj ET Q endstream endobj 187 0 obj <> endobj 188 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The net periodic benefit cost/\(credit\) of defined benefit pension plans includes:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 725.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 725.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 725.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 725.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 725.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 725.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 725.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 699.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 699.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 699.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 699.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 699.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 699.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 699.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 673.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 673.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 673.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 673.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 673.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 673.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 673.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 647.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 647.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 647.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 647.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 647.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 647.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 647.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 621.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 621.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 621.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 621.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 621.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 621.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 621.60 69.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 725.6 m 430.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 725.6 m 503.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 725.6 m 576.5 725.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 621.6 m 430.5 621.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 621.6 m 503.5 621.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 621.6 m 576.5 621.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 609.6 m 430.5 609.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 607.6 m 430.5 607.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 609.6 m 503.5 609.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 607.6 m 503.5 607.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 609.6 m 576.5 609.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 607.6 m 576.5 607.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 729.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.50 729.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 460.50 729.83 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.50 729.83 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 716.17 Td (Service cost — benefits earned during the year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 716.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 716.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 716.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 716.17 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 716.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 716.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 703.17 Td (Interest cost on projected benefit obligation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 703.17 Td (188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 703.17 Td (192) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 703.17 Td (242) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 690.17 Td (Expected return on plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.30 690.22 Td (\(41) Tj ET Q q 0 0 0 rg BT 421.63 690.22 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 690.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.30 690.22 Td (\(418) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 690.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 690.17 Td (\(405) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 690.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 677.17 Td (Amortization of prior service credits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.30 677.22 Td (\(4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 677.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 491.30 677.22 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 677.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 677.17 Td (\(3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 677.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 664.17 Td (Amortization of net actuarial loss) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 664.17 Td (82) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 664.17 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 664.17 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 651.17 Td (Curtailments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.30 651.22 Td (\(8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 426.65 651.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 651.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 564.30 651.17 Td (\(1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 651.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 638.17 Td (Settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.65 638.17 Td (167) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 638.17 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 638.17 Td (161) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 625.17 Td (Special termination benefits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 625.17 Td (3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 625.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 625.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 612.17 Td (Net periodic benefit cost/\(credit\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.00 612.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.65 612.17 Td (42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 437.00 612.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.30 612.22 Td (\(29) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.65 612.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 510.00 612.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 612.17 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 612.17 Td (10) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 585.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 69.79 585.10 Td (settlement ) Tj ET Q q 0 0 0 rg BT 113.01 585.10 Td (char) Tj ET Q q 0 0 0 rg BT 130.04 585.10 Td (ges ) Tj ET Q q 0 0 0 rg BT 145.49 585.10 Td (were ) Tj ET Q q 0 0 0 rg BT 167.04 585.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 213.02 585.10 Td (after ) Tj ET Q q 0 0 0 rg BT 233.46 585.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 283.90 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 298.23 585.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 327.01 585.10 Td (lump ) Tj ET Q q 0 0 0 rg BT 349.69 585.10 Td (sum ) Tj ET Q q 0 0 0 rg BT 368.48 585.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 408.92 585.10 Td (will ) Tj ET Q q 0 0 0 rg BT 426.60 585.10 Td (exceed ) Tj ET Q q 0 0 0 rg BT 456.47 585.10 Td (the ) Tj ET Q q 0 0 0 rg BT 470.81 585.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 499.59 585.10 Td (interest ) Tj ET Q q 0 0 0 rg BT 531.14 585.10 Td (and ) Tj ET Q q 0 0 0 rg BT 547.70 585.10 Td (service ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 573.10 Td (costs ) Tj ET Q q 0 0 0 rg BT 58.50 573.10 Td (for ) Tj ET Q q 0 0 0 rg BT 72.66 573.10 Td (certain ) Tj ET Q q 0 0 0 rg BT 102.36 573.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 135.97 573.10 Td (plans, ) Tj ET Q q 0 0 0 rg BT 162.08 573.10 Td (including ) Tj ET Q q 0 0 0 rg BT 202.35 573.10 Td (the ) Tj ET Q q 0 0 0 rg BT 217.07 573.10 Td (primary ) Tj ET Q q 0 0 0 rg BT 251.22 573.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 271.51 573.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 305.12 573.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 324.83 573.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.11 573.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 355.11 573.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.11 573.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 380.11 573.10 Td ( ) Tj ET Q q 0 0 0 rg BT 382.61 573.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 399.55 573.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 419.55 573.10 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 549.10 Td (Changes ) Tj ET Q q 0 0 0 rg BT 73.42 549.10 Td (in ) Tj ET Q q 0 0 0 rg BT 84.18 549.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 117.15 549.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 147.90 549.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 181.99 549.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 202.19 549.10 Td (obligations, ) Tj ET Q q 0 0 0 rg BT 252.11 549.10 Td (assets, ) Tj ET Q q 0 0 0 rg BT 280.92 549.10 Td (funded ) Tj ET Q q 0 0 0 rg BT 311.67 549.10 Td (status ) Tj ET Q q 0 0 0 rg BT 337.44 549.10 Td (and ) Tj ET Q q 0 0 0 rg BT 354.86 549.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 391.73 549.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 438.57 549.10 Td (in ) Tj ET Q q 0 0 0 rg BT 449.33 549.10 Td (the ) Tj ET Q q 0 0 0 rg BT 464.53 549.10 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 518.05 549.10 Td (balance ) Tj ET Q q 0 0 0 rg BT 551.57 549.10 Td (sheets ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 537.10 Td (were ) Tj ET Q q 0 0 0 rg BT 57.93 537.10 Td (as ) Tj ET Q q 0 0 0 rg BT 68.76 537.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 513.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 513.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 513.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 513.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 513.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 487.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 487.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 487.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 487.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 487.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 461.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 461.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 461.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 461.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 461.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 435.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 435.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 435.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 435.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 435.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 409.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 409.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 409.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 409.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 409.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 383.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 383.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 383.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 383.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 383.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 357.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 357.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 357.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 357.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 357.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 331.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 331.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 331.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 331.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 331.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 305.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 305.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 305.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 305.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 305.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 279.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 279.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 279.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 279.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 279.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 253.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 253.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 253.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 253.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 253.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 227.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 227.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 227.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 227.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 227.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 201.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 201.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 201.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 201.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 201.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 175.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 175.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 175.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 175.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 175.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 149.60 374.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 149.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 149.60 79.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 149.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 149.60 79.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 513.6 m 493.5 513.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 513.6 m 576.5 513.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 422.6 m 493.5 422.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 422.6 m 576.5 422.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 410.6 m 493.5 410.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 408.6 m 493.5 408.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 410.6 m 576.5 410.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 408.6 m 576.5 408.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 318.6 m 493.5 318.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 318.6 m 576.5 318.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 306.6 m 493.5 306.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 304.6 m 493.5 304.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 306.6 m 576.5 306.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 304.6 m 576.5 304.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 292.6 m 493.5 292.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 280.6 m 493.5 280.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 278.6 m 493.5 278.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 292.6 m 576.5 292.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 280.6 m 576.5 280.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 278.6 m 576.5 278.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 214.60000000000002 m 493.5 214.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 214.60000000000002 m 576.5 214.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 202.60000000000002 m 493.5 202.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 200.60000000000002 m 493.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 202.60000000000002 m 576.5 202.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 200.60000000000002 m 576.5 200.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 149.60000000000002 m 493.5 149.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 149.60000000000002 m 576.5 149.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 137.60000000000002 m 493.5 137.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 135.60000000000002 m 493.5 135.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 137.60000000000002 m 576.5 137.60000000000002 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 135.60000000000002 m 576.5 135.60000000000002 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 517.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 445.50 517.83 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.50 517.83 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 504.17 Td (Benefit obligations at beginning of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 504.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 504.17 Td (6,440) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 504.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 504.17 Td (6,418) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 491.17 Td (Service cost—benefits earned during the year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.65 491.17 Td (25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 491.17 Td (24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 478.17 Td (Interest cost) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 478.17 Td (188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 478.17 Td (192) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 465.17 Td (Settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 465.22 Td (\(330) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 465.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 465.17 Td (\(173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 465.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 452.17 Td (Actuarial \(gains\)/losses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 452.17 Td (368) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 452.17 Td (253) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 439.17 Td (Benefits paid) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 439.22 Td (\(121) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 439.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 439.17 Td (\(109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 439.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 426.17 Td (Foreign currency and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 426.17 Td (179) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 426.17 Td (\(165) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 426.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 413.17 Td (Benefit obligations at end of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 413.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 413.17 Td (6,749) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 413.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 413.17 Td (6,440) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 387.17 Td (Fair value of plan assets at beginning of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 387.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 387.17 Td (5,831) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 387.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 387.17 Td (5,687) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 374.17 Td (Actual return on plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 374.17 Td (804) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 374.17 Td (513) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 361.17 Td (Employer contributions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 361.17 Td (396) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 361.17 Td (81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 348.17 Td (Settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 348.22 Td (\(330) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 348.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 348.17 Td (\(173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 348.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 335.17 Td (Benefits paid) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 335.22 Td (\(121) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 335.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 335.17 Td (\(109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 335.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 322.17 Td (Foreign currency and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 322.17 Td (169) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 322.17 Td (\(168) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 322.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 309.17 Td (Fair value of plan assets at end of year) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 309.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 309.17 Td (6,749) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 309.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 309.17 Td (5,831) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 283.17 Td (Funded status) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 283.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.65 283.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 283.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 283.17 Td (\(609) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 283.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 257.17 Td (Assets/\(Liabilities\) recognized:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 244.17 Td (Other assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 244.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.65 244.17 Td (487) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 244.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 244.17 Td (26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 231.17 Td (Accrued liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.30 231.22 Td (\(31) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 231.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 231.17 Td (\(35) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 231.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 218.17 Td (Pension and other liabilities) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 471.30 218.22 Td (\(456) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 218.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 218.17 Td (\(600) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 218.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 205.17 Td (Funded status) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 205.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.65 205.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 205.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 205.17 Td (\(609) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 205.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 179.17 Td (Recognized in accumulated other comprehensive loss:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 166.17 Td (Net actuarial losses) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 166.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 166.17 Td (2,849) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 166.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 166.17 Td (3,123) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 153.17 Td (Prior service credit) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 476.30 153.22 Td (\(36) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 489.65 153.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 153.17 Td (\(39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 153.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 140.17 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 140.17 Td (otal) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 417.00 140.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.15 140.17 Td (2,813) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.00 140.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 140.17 Td (3,084) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 113.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.00 113.10 Td (accumulated ) Tj ET Q q 0 0 0 rg BT 106.97 113.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 137.18 113.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 180.18 113.10 Td (for ) Tj ET Q q 0 0 0 rg BT 194.29 113.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 226.73 113.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 256.94 113.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 290.50 113.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 314.05 113.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.05 113.10 Td ($6.7 ) Tj ET Q q 0 0 0 rg BT 352.00 113.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.12 113.10 Td ( ) Tj ET Q q 0 0 0 rg BT 380.57 113.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.45 113.10 Td ($6.4 ) Tj ET Q q 0 0 0 rg BT 417.40 113.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.51 113.10 Td ( ) Tj ET Q q 0 0 0 rg BT 445.96 113.10 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 455.63 113.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 514.16 113.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 534.16 113.10 Td ( ) Tj ET Q q 0 0 0 rg BT 536.61 113.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.50 113.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.50 113.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 101.10 Td (respectively) Tj ET Q q 0 0 0 rg BT 83.66 101.10 Td (.) Tj ET Q endstream endobj 189 0 obj <> endobj 190 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (Additional information related to pension plans was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 714.60 373.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 714.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 714.60 79.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 714.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 714.60 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 690.60 373.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 690.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 690.60 79.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 690.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 690.60 80.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 666.60 373.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 409.50 666.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 413.50 666.60 79.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 666.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 666.60 80.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 413.5 714.6 m 492.5 714.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 496.5 714.6 m 576.5 714.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 718.55 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.50 718.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.00 718.68 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 705.22 Td (Pension plans with projected benefit obligations in excess of plan assets:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 693.22 Td (Projected benefit obligation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 693.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 693.22 Td (1,166) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 693.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 693.22 Td (6,195) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 681.22 Td (Fair value of plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 681.22 Td (678) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 681.22 Td (5,559) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 669.22 Td (Pension plans with accumulated benefit obligations in excess of plan assets) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 340.04 669.22 Td (:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 657.22 Td (Accumulated benefit obligation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.00 657.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 657.22 Td (1,008) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 657.22 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 657.22 Td (5,978) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 645.22 Td (Fair value of plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 473.65 645.22 Td (550) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 645.22 Td (5,380) Tj ET Q BT /F1 10.00 Tf ET BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 617.10 Td (Actuarial ) Tj ET Q q 0 0 0 rg BT 77.03 617.10 Td (Assumptions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 600.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 600.10 Td (eighted-average assumptions used to determine defined benefit pension plan obligations at December 31 were as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 577.60 374.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 410.50 577.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 414.50 577.60 79.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 493.50 577.60 4.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 497.50 577.60 79.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 414.5 577.6 m 493.5 577.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 497.5 577.6 m 576.5 577.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 581.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 445.50 581.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.50 581.68 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 568.22 Td (Discount rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.15 568.22 Td (3.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 568.22 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 568.22 Td (3.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 568.22 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 556.22 Td (Rate of compensation increase) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.15 556.22 Td (0.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.65 556.22 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 556.22 Td (0.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 556.22 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 530.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 530.10 Td (eighted-average ) Tj ET Q q 0 0 0 rg BT 111.33 530.10 Td (actuarial ) Tj ET Q q 0 0 0 rg BT 148.59 530.10 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 200.88 530.10 Td (used ) Tj ET Q q 0 0 0 rg BT 222.05 530.10 Td (to ) Tj ET Q q 0 0 0 rg BT 232.67 530.10 Td (determine ) Tj ET Q q 0 0 0 rg BT 275.49 530.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 308.32 530.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 338.92 530.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 372.88 530.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 392.93 530.10 Td (net ) Tj ET Q q 0 0 0 rg BT 407.99 530.10 Td (periodic ) Tj ET Q q 0 0 0 rg BT 443.60 530.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 474.20 530.10 Td (\(credit\)/cost ) Tj ET Q q 0 0 0 rg BT 525.36 530.10 Td (for ) Tj ET Q q 0 0 0 rg BT 539.86 530.10 Td (the ) Tj ET Q q 0 0 0 rg BT 554.92 530.10 Td (years ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 518.10 Td (ended ) Tj ET Q q 0 0 0 rg BT 62.38 518.10 Td (December 31 ) Tj ET Q q 0 0 0 rg BT 118.46 518.10 Td (were ) Tj ET Q q 0 0 0 rg BT 140.39 518.10 Td (as ) Tj ET Q q 0 0 0 rg BT 151.22 518.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 495.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 495.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 495.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 495.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 495.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 495.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 495.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 469.60 321.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 469.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 361.50 469.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 469.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 469.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 503.50 469.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 507.50 469.60 69.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 361.5 495.6 m 430.5 495.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 434.5 495.6 m 503.5 495.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 507.5 495.6 m 576.5 495.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 499.55 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 387.50 499.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 460.50 499.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.50 499.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 486.17 Td (Discount rate) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.15 486.17 Td (3.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 486.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 486.17 Td (3.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 486.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 486.17 Td (3.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 486.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 473.17 Td (Expected long-term return on plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.15 473.17 Td (7.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 473.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 473.17 Td (7.2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 473.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 473.17 Td (7.2) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 473.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 460.17 Td (Rate of compensation increase) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.15 460.17 Td (0.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.65 460.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.15 460.17 Td (0.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 494.65 460.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 460.17 Td (0.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 460.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 433.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.01 433.10 Td (yield ) Tj ET Q q 0 0 0 rg BT 76.47 433.10 Td (on ) Tj ET Q q 0 0 0 rg BT 88.93 433.10 Td (high ) Tj ET Q q 0 0 0 rg BT 109.17 433.10 Td (quality ) Tj ET Q q 0 0 0 rg BT 139.41 433.10 Td (corporate ) Tj ET Q q 0 0 0 rg BT 179.62 433.10 Td (bonds ) Tj ET Q q 0 0 0 rg BT 205.98 433.10 Td (matching ) Tj ET Q q 0 0 0 rg BT 245.65 433.10 Td (the ) Tj ET Q q 0 0 0 rg BT 260.33 433.10 Td (duration ) Tj ET Q q 0 0 0 rg BT 296.12 433.10 Td (of ) Tj ET Q q 0 0 0 rg BT 306.91 433.10 Td (the ) Tj ET Q q 0 0 0 rg BT 321.59 433.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 351.81 433.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 398.72 433.10 Td (is ) Tj ET Q q 0 0 0 rg BT 407.85 433.10 Td (used ) Tj ET Q q 0 0 0 rg BT 428.65 433.10 Td (in ) Tj ET Q q 0 0 0 rg BT 438.89 433.10 Td (determining ) Tj ET Q q 0 0 0 rg BT 489.67 433.10 Td (the ) Tj ET Q q 0 0 0 rg BT 504.35 433.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 540.70 433.10 Td (rate. ) Tj ET Q q 0 0 0 rg BT 560.47 433.10 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 421.10 Td (Citi ) Tj ET Q q 0 0 0 rg BT 53.50 421.10 Td (Pension ) Tj ET Q q 0 0 0 rg BT 87.67 421.10 Td (Discount ) Tj ET Q q 0 0 0 rg BT 126.28 421.10 Td (curve ) Tj ET Q q 0 0 0 rg BT 150.99 421.10 Td (is ) Tj ET Q q 0 0 0 rg BT 160.16 421.10 Td (used ) Tj ET Q q 0 0 0 rg BT 180.99 421.10 Td (in ) Tj ET Q q 0 0 0 rg BT 191.27 421.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 238.20 421.10 Td (the ) Tj ET Q q 0 0 0 rg BT 252.92 421.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 289.31 421.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 306.79 421.10 Td (for ) Tj ET Q q 0 0 0 rg BT 320.95 421.10 Td (the ) Tj ET Q q 0 0 0 rg BT 335.67 421.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 355.95 421.10 Td (plans.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 397.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.25 397.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 92.49 397.10 Td (return ) Tj ET Q q 0 0 0 rg BT 119.07 397.10 Td (on ) Tj ET Q q 0 0 0 rg BT 131.77 397.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 151.69 397.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 177.73 397.10 Td (was ) Tj ET Q q 0 0 0 rg BT 195.98 397.10 Td (determined ) Tj ET Q q 0 0 0 rg BT 243.67 397.10 Td (using ) Tj ET Q q 0 0 0 rg BT 268.04 397.10 Td (the ) Tj ET Q q 0 0 0 rg BT 282.96 397.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 321.20 397.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 338.89 397.10 Td (of ) Tj ET Q q 0 0 0 rg BT 349.92 397.10 Td (return ) Tj ET Q q 0 0 0 rg BT 376.50 397.10 Td (and ) Tj ET Q q 0 0 0 rg BT 393.65 397.10 Td (a ) Tj ET Q q 0 0 0 rg BT 400.79 397.10 Td (calculated ) Tj ET Q q 0 0 0 rg BT 444.02 397.10 Td (value ) Tj ET Q q 0 0 0 rg BT 468.38 397.10 Td (of ) Tj ET Q q 0 0 0 rg BT 479.41 397.10 Td (assets, ) Tj ET Q q 0 0 0 rg BT 507.95 397.10 Td (referred ) Tj ET Q q 0 0 0 rg BT 542.29 397.10 Td (to ) Tj ET Q q 0 0 0 rg BT 552.77 397.10 Td (as ) Tj ET Q q 0 0 0 rg BT 563.80 397.10 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 385.10 Td (“market-related ) Tj ET Q q 0 0 0 rg BT 100.90 385.10 Td (value” ) Tj ET Q q 0 0 0 rg BT 129.16 385.10 Td (which ) Tj ET Q q 0 0 0 rg BT 155.76 385.10 Td (approximated ) Tj ET Q q 0 0 0 rg BT 212.91 385.10 Td (the ) Tj ET Q q 0 0 0 rg BT 227.29 385.10 Td (fair ) Tj ET Q q 0 0 0 rg BT 243.33 385.10 Td (value ) Tj ET Q q 0 0 0 rg BT 267.15 385.10 Td (of ) Tj ET Q q 0 0 0 rg BT 277.65 385.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 297.03 385.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 322.53 385.10 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.91 385.10 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 390.16 385.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.16 385.10 Td (. ) Tj ET Q q 0 0 0 rg BT 414.83 385.10 Td (Dif) Tj ET Q q 0 0 0 rg BT 427.98 385.10 Td (ferences ) Tj ET Q q 0 0 0 rg BT 463.45 385.10 Td (between ) Tj ET Q q 0 0 0 rg BT 498.93 385.10 Td (assumed ) Tj ET Q q 0 0 0 rg BT 535.53 385.10 Td (and ) Tj ET Q q 0 0 0 rg BT 552.14 385.10 Td (actual ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 373.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 67.25 373.10 Td (are ) Tj ET Q q 0 0 0 rg BT 82.93 373.10 Td (amortized ) Tj ET Q q 0 0 0 rg BT 126.39 373.10 Td (to ) Tj ET Q q 0 0 0 rg BT 137.65 373.10 Td (the ) Tj ET Q q 0 0 0 rg BT 153.34 373.10 Td (market-related ) Tj ET Q q 0 0 0 rg BT 215.12 373.10 Td (value ) Tj ET Q q 0 0 0 rg BT 240.25 373.10 Td (on ) Tj ET Q q 0 0 0 rg BT 253.73 373.10 Td (a ) Tj ET Q q 0 0 0 rg BT 261.64 373.10 Td (straight-line ) Tj ET Q q 0 0 0 rg BT 313.44 373.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 336.92 373.10 Td (over ) Tj ET Q q 0 0 0 rg BT 358.17 373.10 Td (a ) Tj ET Q q 0 0 0 rg BT 366.08 373.10 Td (three-year ) Tj ET Q q 0 0 0 rg BT 410.08 373.10 Td (period. ) Tj ET Q q 0 0 0 rg BT 441.61 373.10 Td (Several ) Tj ET Q q 0 0 0 rg BT 475.07 373.10 Td (factors ) Tj ET Q q 0 0 0 rg BT 505.76 373.10 Td (are ) Tj ET Q q 0 0 0 rg BT 521.44 373.10 Td (considered ) Tj ET Q q 0 0 0 rg BT 568.23 373.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 361.10 Td (developing ) Tj ET Q q 0 0 0 rg BT 83.12 361.10 Td (the ) Tj ET Q q 0 0 0 rg BT 98.03 361.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 136.25 361.10 Td (return ) Tj ET Q q 0 0 0 rg BT 162.81 361.10 Td (on ) Tj ET Q q 0 0 0 rg BT 175.50 361.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 195.40 361.10 Td (assets, ) Tj ET Q q 0 0 0 rg BT 223.92 361.10 Td (including ) Tj ET Q q 0 0 0 rg BT 264.38 361.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 306.51 361.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 346.41 361.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 376.86 361.10 Td (and ) Tj ET Q q 0 0 0 rg BT 393.99 361.10 Td (input ) Tj ET Q q 0 0 0 rg BT 417.23 361.10 Td (from ) Tj ET Q q 0 0 0 rg BT 439.36 361.10 Td (external ) Tj ET Q q 0 0 0 rg BT 474.25 361.10 Td (advisors. ) Tj ET Q q 0 0 0 rg BT 512.77 361.10 Td (Individual ) Tj ET Q q 0 0 0 rg BT 556.56 361.10 Td (asset ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 349.10 Td (class ) Tj ET Q q 0 0 0 rg BT 57.61 349.10 Td (return ) Tj ET Q q 0 0 0 rg BT 83.65 349.10 Td (forecasts ) Tj ET Q q 0 0 0 rg BT 121.36 349.10 Td (were ) Tj ET Q q 0 0 0 rg BT 142.95 349.10 Td (developed ) Tj ET Q q 0 0 0 rg BT 186.21 349.10 Td (based ) Tj ET Q q 0 0 0 rg BT 211.15 349.10 Td (upon ) Tj ET Q q 0 0 0 rg BT 233.32 349.10 Td (market ) Tj ET Q q 0 0 0 rg BT 263.25 349.10 Td (conditions, ) Tj ET Q q 0 0 0 rg BT 309.58 349.10 Td (for ) Tj ET Q q 0 0 0 rg BT 323.41 349.10 Td (example, ) Tj ET Q q 0 0 0 rg BT 361.95 349.10 Td (price-earnings ) Tj ET Q q 0 0 0 rg BT 421.31 349.10 Td (levels ) Tj ET Q q 0 0 0 rg BT 446.81 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 463.41 349.10 Td (yields ) Tj ET Q q 0 0 0 rg BT 489.47 349.10 Td (and ) Tj ET Q q 0 0 0 rg BT 506.07 349.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 547.67 349.10 Td (growth ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 337.10 Td (expectations. ) Tj ET Q q 0 0 0 rg BT 90.90 337.10 Td (The ) Tj ET Q q 0 0 0 rg BT 109.05 337.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 147.18 337.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 189.22 337.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 206.81 337.10 Td (of ) Tj ET Q q 0 0 0 rg BT 217.74 337.10 Td (return ) Tj ET Q q 0 0 0 rg BT 244.23 337.10 Td (is ) Tj ET Q q 0 0 0 rg BT 253.50 337.10 Td (the ) Tj ET Q q 0 0 0 rg BT 268.32 337.10 Td (weighted-average ) Tj ET Q q 0 0 0 rg BT 341.99 337.10 Td (of ) Tj ET Q q 0 0 0 rg BT 352.93 337.10 Td (the ) Tj ET Q q 0 0 0 rg BT 367.75 337.10 Td (tar) Tj ET Q q 0 0 0 rg BT 378.11 337.10 Td (get ) Tj ET Q q 0 0 0 rg BT 392.94 337.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 414.98 337.10 Td (allocation ) Tj ET Q q 0 0 0 rg BT 457.01 337.10 Td (of ) Tj ET Q q 0 0 0 rg BT 467.94 337.10 Td (each ) Tj ET Q q 0 0 0 rg BT 488.86 337.10 Td (individual ) Tj ET Q q 0 0 0 rg BT 532.02 337.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 554.06 337.10 Td (class. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.10 Td (Historical ) Tj ET Q q 0 0 0 rg BT 77.93 325.10 Td (long-term ) Tj ET Q q 0 0 0 rg BT 119.87 325.10 Td (actual ) Tj ET Q q 0 0 0 rg BT 146.24 325.10 Td (annualized ) Tj ET Q q 0 0 0 rg BT 192.05 325.10 Td (returns ) Tj ET Q q 0 0 0 rg BT 222.32 325.10 Td (for ) Tj ET Q q 0 0 0 rg BT 236.48 325.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 256.76 325.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 290.37 325.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 313.98 325.10 Td (were ) Tj ET Q q 0 0 0 rg BT 335.91 325.10 Td (as ) Tj ET Q q 0 0 0 rg BT 346.74 325.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 302.60 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 302.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 302.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 302.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 302.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 302.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 302.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 276.60 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 276.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 276.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 276.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 276.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 276.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 276.60 70.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 360.5 302.6 m 429.5 302.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 433.5 302.6 m 502.5 302.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 506.5 302.6 m 576.5 302.6 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 386.50 306.68 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 459.50 306.68 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 533.00 306.68 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 293.17 Td (10 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 293.17 Td (6.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 293.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 293.17 Td (6.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 293.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 293.17 Td (6.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 293.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 280.17 Td (15 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 280.17 Td (9.3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 280.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 280.17 Td (7.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 280.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 280.17 Td (6.0) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 280.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 267.17 Td (20 years) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 267.17 Td (7.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 267.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.15 267.17 Td (7.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.65 267.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 267.17 Td (8.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 267.17 Td (%) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 240.10 Td (Actuarial ) Tj ET Q q 0 0 0 rg BT 76.22 240.10 Td (gains ) Tj ET Q q 0 0 0 rg BT 100.35 240.10 Td (and ) Tj ET Q q 0 0 0 rg BT 117.81 240.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 144.72 240.10 Td (resulted ) Tj ET Q q 0 0 0 rg BT 179.40 240.10 Td (from ) Tj ET Q q 0 0 0 rg BT 201.85 240.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 237.08 240.10 Td (in ) Tj ET Q q 0 0 0 rg BT 247.88 240.10 Td (actuarial ) Tj ET Q q 0 0 0 rg BT 285.32 240.10 Td (assumptions ) Tj ET Q q 0 0 0 rg BT 337.79 240.10 Td (\(such ) Tj ET Q q 0 0 0 rg BT 362.47 240.10 Td (as ) Tj ET Q q 0 0 0 rg BT 373.82 240.10 Td (changes ) Tj ET Q q 0 0 0 rg BT 409.04 240.10 Td (in ) Tj ET Q q 0 0 0 rg BT 419.84 240.10 Td (the ) Tj ET Q q 0 0 0 rg BT 435.08 240.10 Td (discount ) Tj ET Q q 0 0 0 rg BT 471.99 240.10 Td (rate ) Tj ET Q q 0 0 0 rg BT 489.99 240.10 Td (and ) Tj ET Q q 0 0 0 rg BT 507.45 240.10 Td (revised ) Tj ET Q q 0 0 0 rg BT 539.35 240.10 Td (mortality ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.10 Td (rates\) ) Tj ET Q q 0 0 0 rg BT 61.42 228.10 Td (and ) Tj ET Q q 0 0 0 rg BT 79.07 228.10 Td (from ) Tj ET Q q 0 0 0 rg BT 101.73 228.10 Td (dif) Tj ET Q q 0 0 0 rg BT 112.65 228.10 Td (ferences ) Tj ET Q q 0 0 0 rg BT 149.17 228.10 Td (between ) Tj ET Q q 0 0 0 rg BT 185.70 228.10 Td (assumed ) Tj ET Q q 0 0 0 rg BT 223.36 228.10 Td (and ) Tj ET Q q 0 0 0 rg BT 241.01 228.10 Td (actual ) Tj ET Q q 0 0 0 rg BT 268.10 228.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 314.61 228.10 Td (\(such ) Tj ET Q q 0 0 0 rg BT 339.49 228.10 Td (as ) Tj ET Q q 0 0 0 rg BT 351.03 228.10 Td (dif) Tj ET Q q 0 0 0 rg BT 361.96 228.10 Td (ferences ) Tj ET Q q 0 0 0 rg BT 398.48 228.10 Td (between ) Tj ET Q q 0 0 0 rg BT 435.01 228.10 Td (actual ) Tj ET Q q 0 0 0 rg BT 462.09 228.10 Td (and ) Tj ET Q q 0 0 0 rg BT 479.75 228.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 518.49 228.10 Td (return ) Tj ET Q q 0 0 0 rg BT 545.59 228.10 Td (on ) Tj ET Q q 0 0 0 rg BT 558.80 228.10 Td (plan ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.10 Td (assets\). ) Tj ET Q q 0 0 0 rg BT 67.81 216.10 Td (Gains ) Tj ET Q q 0 0 0 rg BT 93.79 216.10 Td (and ) Tj ET Q q 0 0 0 rg BT 110.87 216.10 Td (losses ) Tj ET Q q 0 0 0 rg BT 137.41 216.10 Td (are ) Tj ET Q q 0 0 0 rg BT 152.27 216.10 Td (amortized ) Tj ET Q q 0 0 0 rg BT 194.90 216.10 Td (over ) Tj ET Q q 0 0 0 rg BT 215.31 216.10 Td (the ) Tj ET Q q 0 0 0 rg BT 230.18 216.10 Td (life ) Tj ET Q q 0 0 0 rg BT 246.15 216.10 Td (expectancy ) Tj ET Q q 0 0 0 rg BT 293.77 216.10 Td (of ) Tj ET Q q 0 0 0 rg BT 304.75 216.10 Td (the ) Tj ET Q q 0 0 0 rg BT 319.61 216.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 339.48 216.10 Td (participants ) Tj ET Q q 0 0 0 rg BT 388.77 216.10 Td (for ) Tj ET Q q 0 0 0 rg BT 403.08 216.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 423.51 216.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 447.27 216.10 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 450.60 216.10 Td (34) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.60 216.10 Td ( ) Tj ET Q q 0 0 0 rg BT 463.25 216.10 Td (years ) Tj ET Q q 0 0 0 rg BT 486.99 216.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.42 216.10 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 517.42 216.10 Td (\) ) Tj ET Q q 0 0 0 rg BT 523.40 216.10 Td (and ) Tj ET Q q 0 0 0 rg BT 540.49 216.10 Td (expected ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.10 Td (remaining ) Tj ET Q q 0 0 0 rg BT 79.13 204.10 Td (service ) Tj ET Q q 0 0 0 rg BT 110.03 204.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 142.05 204.10 Td (for ) Tj ET Q q 0 0 0 rg BT 156.30 204.10 Td (most ) Tj ET Q q 0 0 0 rg BT 178.33 204.10 Td (other ) Tj ET Q q 0 0 0 rg BT 201.46 204.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 225.16 204.10 Td (to ) Tj ET Q q 0 0 0 rg BT 235.52 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 250.32 204.10 Td (extent ) Tj ET Q q 0 0 0 rg BT 277.34 204.10 Td (they ) Tj ET Q q 0 0 0 rg BT 297.15 204.10 Td (exceed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 327.48 204.10 Td (10%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 345.81 204.10 Td ( ) Tj ET Q q 0 0 0 rg BT 348.40 204.10 Td (of ) Tj ET Q q 0 0 0 rg BT 359.32 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 374.12 204.10 Td (higher ) Tj ET Q q 0 0 0 rg BT 402.25 204.10 Td (of ) Tj ET Q q 0 0 0 rg BT 413.17 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 427.97 204.10 Td (market-related ) Tj ET Q q 0 0 0 rg BT 488.85 204.10 Td (value ) Tj ET Q q 0 0 0 rg BT 513.09 204.10 Td (or ) Tj ET Q q 0 0 0 rg BT 524.01 204.10 Td (the ) Tj ET Q q 0 0 0 rg BT 538.81 204.10 Td (projected ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 192.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 65.91 192.10 Td (obligation ) Tj ET Q q 0 0 0 rg BT 108.60 192.10 Td (for ) Tj ET Q q 0 0 0 rg BT 122.41 192.10 Td (each ) Tj ET Q q 0 0 0 rg BT 142.87 192.10 Td (respective ) Tj ET Q q 0 0 0 rg BT 185.54 192.10 Td (plan. ) Tj ET Q q 0 0 0 rg BT 207.25 192.10 Td (The ) Tj ET Q q 0 0 0 rg BT 224.94 192.10 Td (amortization ) Tj ET Q q 0 0 0 rg BT 277.62 192.10 Td (of ) Tj ET Q q 0 0 0 rg BT 288.09 192.10 Td (net ) Tj ET Q q 0 0 0 rg BT 302.45 192.10 Td (actuarial ) Tj ET Q q 0 0 0 rg BT 339.01 192.10 Td (loss ) Tj ET Q q 0 0 0 rg BT 356.72 192.10 Td (and ) Tj ET Q q 0 0 0 rg BT 373.30 192.10 Td (prior ) Tj ET Q q 0 0 0 rg BT 394.88 192.10 Td (service ) Tj ET Q q 0 0 0 rg BT 425.34 192.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 450.25 192.10 Td (is ) Tj ET Q q 0 0 0 rg BT 459.06 192.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 496.74 192.10 Td (to ) Tj ET Q q 0 0 0 rg BT 506.66 192.10 Td (be ) Tj ET Q q 0 0 0 rg BT 518.24 192.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 180.10 Td ($80 ) Tj ET Q q 0 0 0 rg BT 53.69 180.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 82.58 180.10 Td ( ) Tj ET Q q 0 0 0 rg BT 85.27 180.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 95.73 180.10 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 115.73 180.10 Td (. ) Tj ET Q q 0 0 0 rg BT 120.73 180.10 Td (The ) Tj ET Q q 0 0 0 rg BT 138.96 180.10 Td (periodic ) Tj ET Q q 0 0 0 rg BT 174.41 180.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 204.87 180.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 223.66 180.10 Td (or ) Tj ET Q q 0 0 0 rg BT 234.68 180.10 Td (credit ) Tj ET Q q 0 0 0 rg BT 260.13 180.10 Td (is ) Tj ET Q q 0 0 0 rg BT 269.49 180.10 Td (included ) Tj ET Q q 0 0 0 rg BT 306.61 180.10 Td (in ) Tj ET Q q 0 0 0 rg BT 317.08 180.10 Td (cost ) Tj ET Q q 0 0 0 rg BT 335.87 180.10 Td (of ) Tj ET Q q 0 0 0 rg BT 346.89 180.10 Td (products ) Tj ET Q q 0 0 0 rg BT 384.02 180.10 Td (sold, ) Tj ET Q q 0 0 0 rg BT 405.88 180.10 Td (research ) Tj ET Q q 0 0 0 rg BT 441.87 180.10 Td (and ) Tj ET Q q 0 0 0 rg BT 459.00 180.10 Td (development, ) Tj ET Q q 0 0 0 rg BT 515.83 180.10 Td (and ) Tj ET Q q 0 0 0 rg BT 532.96 180.10 Td (marketing, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 168.10 Td (selling ) Tj ET Q q 0 0 0 rg BT 65.73 168.10 Td (and ) Tj ET Q q 0 0 0 rg BT 83.24 168.10 Td (administrative ) Tj ET Q q 0 0 0 rg BT 143.51 168.10 Td (expenses, ) Tj ET Q q 0 0 0 rg BT 185.17 168.10 Td (except ) Tj ET Q q 0 0 0 rg BT 214.33 168.10 Td (for ) Tj ET Q q 0 0 0 rg BT 229.06 168.10 Td (curtailments, ) Tj ET Q q 0 0 0 rg BT 284.06 168.10 Td (settlements ) Tj ET Q q 0 0 0 rg BT 332.11 168.10 Td (and ) Tj ET Q q 0 0 0 rg BT 349.62 168.10 Td (other ) Tj ET Q q 0 0 0 rg BT 373.23 168.10 Td (special ) Tj ET Q q 0 0 0 rg BT 404.06 168.10 Td (termination ) Tj ET Q q 0 0 0 rg BT 453.23 168.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 487.95 168.10 Td (which ) Tj ET Q q 0 0 0 rg BT 515.45 168.10 Td (are ) Tj ET Q q 0 0 0 rg BT 530.73 168.10 Td (included ) Tj ET Q q 0 0 0 rg BT 568.23 168.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 156.10 Td (other ) Tj ET Q q 0 0 0 rg BT 59.05 156.10 Td (expenses.) Tj ET Q endstream endobj 191 0 obj <> endobj 192 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (95) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Postretirement ) Tj ET Q q 0 0 0 rg BT 99.05 749.25 Td (Benefit ) Tj ET Q q 0 0 0 rg BT 131.55 749.25 Td (Plans) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.25 Td (Comprehensive ) Tj ET Q q 0 0 0 rg BT 101.45 725.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 135.79 725.25 Td (and ) Tj ET Q q 0 0 0 rg BT 152.92 725.25 Td (group ) Tj ET Q q 0 0 0 rg BT 178.94 725.25 Td (life ) Tj ET Q q 0 0 0 rg BT 194.96 725.25 Td (benefits ) Tj ET Q q 0 0 0 rg BT 229.31 725.25 Td (are ) Tj ET Q q 0 0 0 rg BT 244.20 725.25 Td (provided ) Tj ET Q q 0 0 0 rg BT 282.44 725.25 Td (for ) Tj ET Q q 0 0 0 rg BT 296.79 725.25 Td (substantially ) Tj ET Q q 0 0 0 rg BT 350.03 725.25 Td (all ) Tj ET Q q 0 0 0 rg BT 362.72 725.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 383.19 725.25 Td (retirees ) Tj ET Q q 0 0 0 rg BT 415.31 725.25 Td (electing ) Tj ET Q q 0 0 0 rg BT 449.65 725.25 Td (to ) Tj ET Q q 0 0 0 rg BT 460.12 725.25 Td (participate ) Tj ET Q q 0 0 0 rg BT 505.00 725.25 Td (in ) Tj ET Q q 0 0 0 rg BT 515.47 725.25 Td (comprehensive ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 69.31 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 85.40 713.25 Td (group ) Tj ET Q q 0 0 0 rg BT 110.39 713.25 Td (life ) Tj ET Q q 0 0 0 rg BT 125.38 713.25 Td (plans ) Tj ET Q q 0 0 0 rg BT 148.14 713.25 Td (and ) Tj ET Q q 0 0 0 rg BT 164.24 713.25 Td (to ) Tj ET Q q 0 0 0 rg BT 173.67 713.25 Td (a ) Tj ET Q q 0 0 0 rg BT 179.77 713.25 Td (lesser ) Tj ET Q q 0 0 0 rg BT 204.20 713.25 Td (extent ) Tj ET Q q 0 0 0 rg BT 230.29 713.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 259.15 713.25 Td (benefits ) Tj ET Q q 0 0 0 rg BT 292.46 713.25 Td (for ) Tj ET Q q 0 0 0 rg BT 305.78 713.25 Td (non-U.S. ) Tj ET Q q 0 0 0 rg BT 343.55 713.25 Td (employees. ) Tj ET Q q 0 0 0 rg BT 390.35 713.25 Td (The ) Tj ET Q q 0 0 0 rg BT 407.56 713.25 Td (medical ) Tj ET Q q 0 0 0 rg BT 440.86 713.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 459.74 713.25 Td (is ) Tj ET Q q 0 0 0 rg BT 468.07 713.25 Td (contributory) Tj ET Q q 0 0 0 rg BT 516.85 713.25 Td (. ) Tj ET Q q 0 0 0 rg BT 521.01 713.25 Td (Contributions ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.25 Td (are ) Tj ET Q q 0 0 0 rg BT 51.27 701.25 Td (adjusted ) Tj ET Q q 0 0 0 rg BT 87.67 701.25 Td (periodically ) Tj ET Q q 0 0 0 rg BT 138.49 701.25 Td (and ) Tj ET Q q 0 0 0 rg BT 156.00 701.25 Td (vary ) Tj ET Q q 0 0 0 rg BT 176.83 701.25 Td (by ) Tj ET Q q 0 0 0 rg BT 189.90 701.25 Td (date ) Tj ET Q q 0 0 0 rg BT 209.62 701.25 Td (of ) Tj ET Q q 0 0 0 rg BT 221.01 701.25 Td (retirement. ) Tj ET Q q 0 0 0 rg BT 267.45 701.25 Td (The ) Tj ET Q q 0 0 0 rg BT 286.06 701.25 Td (life ) Tj ET Q q 0 0 0 rg BT 302.45 701.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 343.83 701.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 364.12 701.25 Td (is ) Tj ET Q q 0 0 0 rg BT 373.85 701.25 Td (noncontributory) Tj ET Q q 0 0 0 rg BT 437.64 701.25 Td (. ) Tj ET Q q 0 0 0 rg BT 443.21 701.25 Td (Plan ) Tj ET Q q 0 0 0 rg BT 464.05 701.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 490.45 701.25 Td (consist ) Tj ET Q q 0 0 0 rg BT 521.29 701.25 Td (principally ) Tj ET Q q 0 0 0 rg BT 567.68 701.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 689.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 63.76 689.25 Td (and ) Tj ET Q q 0 0 0 rg BT 80.97 689.25 Td (fixed-income ) Tj ET Q q 0 0 0 rg BT 137.05 689.25 Td (securities. ) Tj ET Q q 0 0 0 rg BT 180.08 689.25 Td (Postretirement ) Tj ET Q q 0 0 0 rg BT 241.17 689.25 Td (benefit ) Tj ET Q q 0 0 0 rg BT 271.70 689.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 291.69 689.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 338.90 689.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 361.10 689.25 Td ($298 ) Tj ET Q q 0 0 0 rg BT 383.87 689.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.76 689.25 Td ( ) Tj ET Q q 0 0 0 rg BT 415.53 689.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 432.73 689.25 Td ($308 ) Tj ET Q q 0 0 0 rg BT 455.50 689.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.39 689.25 Td ( ) Tj ET Q q 0 0 0 rg BT 487.16 689.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 497.15 689.25 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 556.00 689.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 677.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 52.33 677.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 72.33 677.25 Td (, ) Tj ET Q q 0 0 0 rg BT 76.73 677.25 Td (respectively) Tj ET Q q 0 0 0 rg BT 124.39 677.25 Td (, ) Tj ET Q q 0 0 0 rg BT 128.78 677.25 Td (and ) Tj ET Q q 0 0 0 rg BT 145.12 677.25 Td (the ) Tj ET Q q 0 0 0 rg BT 159.23 677.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 175.00 677.25 Td (value ) Tj ET Q q 0 0 0 rg BT 198.55 677.25 Td (of ) Tj ET Q q 0 0 0 rg BT 208.77 677.25 Td (plan ) Tj ET Q q 0 0 0 rg BT 227.88 677.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 253.11 677.25 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 274.43 677.25 Td ($364 ) Tj ET Q q 0 0 0 rg BT 296.33 677.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.22 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 327.11 677.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 343.45 677.25 Td ($331 ) Tj ET Q q 0 0 0 rg BT 365.34 677.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.23 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 396.13 677.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.24 677.25 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 463.22 677.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.22 677.25 Td ( ) Tj ET Q q 0 0 0 rg BT 485.11 677.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.44 677.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.44 677.25 Td (, ) Tj ET Q q 0 0 0 rg BT 525.84 677.25 Td (respectively) Tj ET Q q 0 0 0 rg BT 573.50 677.25 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 665.25 Td (The ) Tj ET Q q 0 0 0 rg BT 52.89 665.25 Td (weighted-average ) Tj ET Q q 0 0 0 rg BT 125.30 665.25 Td (discount ) Tj ET Q q 0 0 0 rg BT 160.53 665.25 Td (rate ) Tj ET Q q 0 0 0 rg BT 176.86 665.25 Td (used ) Tj ET Q q 0 0 0 rg BT 196.53 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 205.65 665.25 Td (determine ) Tj ET Q q 0 0 0 rg BT 246.98 665.25 Td (benefit ) Tj ET Q q 0 0 0 rg BT 276.08 665.25 Td (obligations ) Tj ET Q q 0 0 0 rg BT 321.87 665.25 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 338.76 665.25 Td (3.3%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.59 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 360.94 665.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 376.72 665.25 Td (3.6%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.55 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 398.89 665.25 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.45 665.25 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 464.88 665.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.88 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 486.22 665.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.00 665.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.00 665.25 Td (, ) Tj ET Q q 0 0 0 rg BT 525.84 665.25 Td (respectively) Tj ET Q q 0 0 0 rg BT 573.50 665.25 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 653.25 Td (net ) Tj ET Q q 0 0 0 rg BT 68.76 653.25 Td (periodic ) Tj ET Q q 0 0 0 rg BT 104.03 653.25 Td (benefit ) Tj ET Q q 0 0 0 rg BT 134.29 653.25 Td (credits ) Tj ET Q q 0 0 0 rg BT 163.45 653.25 Td (were ) Tj ET Q q 0 0 0 rg BT 185.38 653.25 Td (not ) Tj ET Q q 0 0 0 rg BT 200.65 653.25 Td (material.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (Plan ) Tj ET Q q 0 0 0 rg BT 57.58 629.25 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 613.25 Td (The fair value of pension and postretirement plan assets by asset category at December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.42 613.25 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 421.42 613.25 Td ( and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 440.86 613.25 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.86 613.25 Td ( was as follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 576.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 576.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 576.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 550.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 550.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 550.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 524.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 524.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 524.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 498.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 498.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 498.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 472.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 472.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 472.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 446.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 446.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 446.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 429.75 246.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 370.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 408.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 412.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 450.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 454.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 492.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 496.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 534.50 429.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 538.50 429.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 403.75 204.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 240.50 403.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 244.50 403.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 282.50 403.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 286.50 403.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 324.50 403.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 328.50 403.75 38.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 366.50 403.75 4.00 -13.00 re f /GS0 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408.5 364.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 370.5 352.75 m 408.5 352.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 370.5 350.75 m 408.5 350.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 538.5 364.75 m 576.5 364.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 538.5 352.75 m 576.5 352.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 538.5 350.75 m 576.5 350.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 594.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 293.75 593.98 Td (December) Tj ET Q q 0 0 0 rg BT 328.32 593.98 Td ( 31, 2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 461.75 593.98 Td (December) Tj ET Q q 0 0 0 rg BT 496.32 593.98 Td ( 31, 2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 581.00 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 250.65 580.98 Td (Level 1) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 292.65 580.98 Td (Level 2) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 334.65 580.98 Td (Level 3) Tj ET Q BT /F2 8.00 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476.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 476.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 476.32 Td (1) Tj ET Q q 0 0 0 rg BT 520.65 476.32 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 476.32 Td (1) Tj ET Q q 0 0 0 rg BT 562.65 476.32 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 463.32 Td (Cash and cash equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.65 463.32 Td (214) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.65 463.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.65 463.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 463.32 Td (214) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.65 463.32 Td (81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 463.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.65 463.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 463.32 Td (81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 450.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.65 450.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.65 450.32 Td (92) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.65 450.32 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 450.32 Td (105) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 436.65 450.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.65 450.32 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 520.65 450.32 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 450.32 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 437.32 Td (Plan assets subject to leveling) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 247.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.10 437.32 Td (1,173) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 289.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.10 437.32 Td (4,957) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.65 437.32 Td (151) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.10 437.32 Td (6,281) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 424.10 437.32 Td (1,052) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.10 437.32 Td (4,158) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 499.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 515.65 437.32 Td (1) Tj ET Q q 0 0 0 rg BT 520.65 437.32 Td (12) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 541.00 437.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.10 437.32 Td (5,322) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 420.48 Td (Plan assets measur) Tj ET Q q 0 0 0 rg BT 119.37 420.48 Td (ed at NA) Tj ET Q q 0 0 0 rg BT 155.86 420.48 Td (V) Tj ET Q q 0 0 0 rg BT 162.90 420.48 Td ( as a practical expedient) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 407.32 Td (Equity funds) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.00 407.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 407.32 Td (488) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 541.00 407.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 407.32 Td (476) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 394.32 Td (V) Tj ET Q q 0 0 0 rg BT 45.67 394.32 Td (enture capital and limited partnerships) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 394.32 Td (154) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 394.32 Td (198) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 381.32 Td (Other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 381.32 Td (191) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 381.32 Td (166) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 368.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 368.32 Td (otal plan assets measured at NA) Tj ET Q q 0 0 0 rg BT 171.14 368.32 Td (V) Tj ET Q q 0 0 0 rg BT 178.18 368.32 Td ( as a practical expedient) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.65 368.32 Td (833) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 368.32 Td (840) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 355.32 Td (Net plan assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 373.00 355.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.10 355.32 Td (7,1) Tj ET Q q 0 0 0 rg BT 394.60 355.32 Td (14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 541.00 355.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.10 355.32 Td (6,162) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 334.25 Td (The investment valuation policies per investment class are as follows:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 317.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 87.38 317.25 Td (1 ) Tj ET Q q 0 0 0 rg BT 93.99 317.25 Td (inputs ) Tj ET Q q 0 0 0 rg BT 120.06 317.25 Td (utilize ) Tj ET Q q 0 0 0 rg BT 146.66 317.25 Td (unadjusted ) Tj ET Q q 0 0 0 rg BT 191.60 317.25 Td (quoted ) Tj ET Q q 0 0 0 rg BT 220.44 317.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 245.93 317.25 Td (in ) Tj ET Q q 0 0 0 rg BT 255.32 317.25 Td (active ) Tj ET Q q 0 0 0 rg BT 280.81 317.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 314.08 317.25 Td (accessible ) Tj ET Q q 0 0 0 rg BT 356.23 317.25 Td (at ) Tj ET Q q 0 0 0 rg BT 365.06 317.25 Td (the ) Tj ET Q q 0 0 0 rg BT 378.89 317.25 Td (measurement ) Tj ET Q q 0 0 0 rg BT 433.82 317.25 Td (date ) Tj ET Q q 0 0 0 rg BT 452.09 317.25 Td (for ) Tj ET Q q 0 0 0 rg BT 465.36 317.25 Td (identical ) Tj ET Q q 0 0 0 rg BT 501.41 317.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 526.35 317.25 Td (or ) Tj ET Q q 0 0 0 rg BT 536.30 317.25 Td (liabilities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 305.25 Td (The ) Tj ET Q q 0 0 0 rg BT 80.98 305.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 97.30 305.25 Td (value ) Tj ET Q q 0 0 0 rg BT 121.39 305.25 Td (hierarchy ) Tj ET Q q 0 0 0 rg BT 161.58 305.25 Td (provides ) Tj ET Q q 0 0 0 rg BT 198.46 305.25 Td (the ) Tj ET Q q 0 0 0 rg BT 213.12 305.25 Td (highest ) Tj ET Q q 0 0 0 rg BT 244.44 305.25 Td (priority ) Tj ET Q q 0 0 0 rg BT 276.87 305.25 Td (to ) Tj ET Q q 0 0 0 rg BT 287.09 305.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 312.29 305.25 Td (1 ) Tj ET Q q 0 0 0 rg BT 319.73 305.25 Td (inputs. ) Tj ET Q q 0 0 0 rg BT 348.94 305.25 Td (These ) Tj ET Q q 0 0 0 rg BT 375.25 305.25 Td (instruments ) Tj ET Q q 0 0 0 rg BT 424.36 305.25 Td (include ) Tj ET Q q 0 0 0 rg BT 456.23 305.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 483.66 305.25 Td (securities, ) Tj ET Q q 0 0 0 rg BT 526.36 305.25 Td (equity ) Tj ET Q q 0 0 0 rg BT 553.80 305.25 Td (funds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 79.21 293.25 Td (fixed ) Tj ET Q q 0 0 0 rg BT 101.54 293.25 Td (income ) Tj ET Q q 0 0 0 rg BT 132.74 293.25 Td (funds ) Tj ET Q q 0 0 0 rg BT 156.74 293.25 Td (publicly ) Tj ET Q q 0 0 0 rg BT 191.29 293.25 Td (traded ) Tj ET Q q 0 0 0 rg BT 218.05 293.25 Td (on ) Tj ET Q q 0 0 0 rg BT 229.82 293.25 Td (a ) Tj ET Q q 0 0 0 rg BT 236.04 293.25 Td (national ) Tj ET Q q 0 0 0 rg BT 270.02 293.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 309.56 293.25 Td (exchange, ) Tj ET Q q 0 0 0 rg BT 351.59 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 367.80 293.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 387.35 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 403.56 293.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 423.10 293.25 Td (equivalents. ) Tj ET Q q 0 0 0 rg BT 472.92 293.25 Td (Cash ) Tj ET Q q 0 0 0 rg BT 494.70 293.25 Td (and ) Tj ET Q q 0 0 0 rg BT 510.91 293.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 530.45 293.25 Td (equivalents ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 281.25 Td (are ) Tj ET Q q 0 0 0 rg BT 77.91 281.25 Td (highly ) Tj ET Q q 0 0 0 rg BT 106.17 281.25 Td (liquid ) Tj ET Q q 0 0 0 rg BT 132.21 281.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 182.68 281.25 Td (with ) Tj ET Q q 0 0 0 rg BT 203.16 281.25 Td (original ) Tj ET Q q 0 0 0 rg BT 236.97 281.25 Td (maturities ) Tj ET Q q 0 0 0 rg BT 279.66 281.25 Td (of ) Tj ET Q q 0 0 0 rg BT 290.70 281.25 Td (three ) Tj ET Q q 0 0 0 rg BT 313.38 281.25 Td (months ) Tj ET Q q 0 0 0 rg BT 345.53 281.25 Td (or ) Tj ET Q q 0 0 0 rg BT 356.57 281.25 Td (less ) Tj ET Q q 0 0 0 rg BT 374.27 281.25 Td (at ) Tj ET Q q 0 0 0 rg BT 384.19 281.25 Td (the ) Tj ET Q q 0 0 0 rg BT 399.11 281.25 Td (time ) Tj ET Q q 0 0 0 rg BT 419.58 281.25 Td (of ) Tj ET Q q 0 0 0 rg BT 430.62 281.25 Td (purchase ) Tj ET Q q 0 0 0 rg BT 468.86 281.25 Td (and ) Tj ET Q q 0 0 0 rg BT 486.00 281.25 Td (are ) Tj ET Q q 0 0 0 rg BT 500.91 281.25 Td (recognized ) Tj ET Q q 0 0 0 rg BT 547.47 281.25 Td (at ) Tj ET Q q 0 0 0 rg BT 557.39 281.25 Td (cost, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 269.25 Td (which ) Tj ET Q q 0 0 0 rg BT 89.68 269.25 Td (approximates ) Tj ET Q q 0 0 0 rg BT 145.80 269.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 161.92 269.25 Td (value. ) Tj ET Q q 0 0 0 rg BT 188.32 269.25 Td (Pending ) Tj ET Q q 0 0 0 rg BT 223.35 269.25 Td (trade ) Tj ET Q q 0 0 0 rg BT 245.58 269.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 267.26 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 283.94 269.25 Td (purchases ) Tj ET Q q 0 0 0 rg BT 325.62 269.25 Td (are ) Tj ET Q q 0 0 0 rg BT 340.07 269.25 Td (included ) Tj ET Q q 0 0 0 rg BT 376.75 269.25 Td (in ) Tj ET Q q 0 0 0 rg BT 386.77 269.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 406.79 269.25 Td (and ) Tj ET Q q 0 0 0 rg BT 423.47 269.25 Td (cash ) Tj ET Q q 0 0 0 rg BT 443.48 269.25 Td (equivalents ) Tj ET Q q 0 0 0 rg BT 491.27 269.25 Td (until ) Tj ET Q q 0 0 0 rg BT 511.85 269.25 Td (final ) Tj ET Q q 0 0 0 rg BT 532.42 269.25 Td (settlement.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 252.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 88.71 252.25 Td (2 ) Tj ET Q q 0 0 0 rg BT 96.66 252.25 Td (inputs ) Tj ET Q q 0 0 0 rg BT 124.05 252.25 Td (utilize ) Tj ET Q q 0 0 0 rg BT 151.99 252.25 Td (observable ) Tj ET Q q 0 0 0 rg BT 198.25 252.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 225.07 252.25 Td (for ) Tj ET Q q 0 0 0 rg BT 239.68 252.25 Td (similar ) Tj ET Q q 0 0 0 rg BT 270.39 252.25 Td (instruments, ) Tj ET Q q 0 0 0 rg BT 322.51 252.25 Td (quoted ) Tj ET Q q 0 0 0 rg BT 352.67 252.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 379.49 252.25 Td (for ) Tj ET Q q 0 0 0 rg BT 394.10 252.25 Td (identical ) Tj ET Q q 0 0 0 rg BT 431.47 252.25 Td (or ) Tj ET Q q 0 0 0 rg BT 442.75 252.25 Td (similar ) Tj ET Q q 0 0 0 rg BT 473.47 252.25 Td (instruments ) Tj ET Q q 0 0 0 rg BT 523.08 252.25 Td (in ) Tj ET Q q 0 0 0 rg BT 533.80 252.25 Td (non-active ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 240.25 Td (markets, ) Tj ET Q q 0 0 0 rg BT 98.76 240.25 Td (and ) Tj ET Q q 0 0 0 rg BT 114.81 240.25 Td (other ) Tj ET Q q 0 0 0 rg BT 136.96 240.25 Td (observable ) Tj ET Q q 0 0 0 rg BT 181.88 240.25 Td (inputs ) Tj ET Q q 0 0 0 rg BT 207.94 240.25 Td (that ) Tj ET Q q 0 0 0 rg BT 224.54 240.25 Td (can ) Tj ET Q q 0 0 0 rg BT 240.02 240.25 Td (be ) Tj ET Q q 0 0 0 rg BT 251.07 240.25 Td (corroborated ) Tj ET Q q 0 0 0 rg BT 303.76 240.25 Td (by ) Tj ET Q q 0 0 0 rg BT 315.36 240.25 Td (market ) Tj ET Q q 0 0 0 rg BT 344.73 240.25 Td (data ) Tj ET Q q 0 0 0 rg BT 363.00 240.25 Td (for ) Tj ET Q q 0 0 0 rg BT 376.26 240.25 Td (substantially ) Tj ET Q q 0 0 0 rg BT 428.42 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 442.24 240.25 Td (full ) Tj ET Q q 0 0 0 rg BT 457.74 240.25 Td (term ) Tj ET Q q 0 0 0 rg BT 477.67 240.25 Td (of ) Tj ET Q q 0 0 0 rg BT 487.60 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 501.43 240.25 Td (assets ) Tj ET Q q 0 0 0 rg BT 526.36 240.25 Td (or ) Tj ET Q q 0 0 0 rg BT 536.30 240.25 Td (liabilities. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 228.25 Td (Equity ) Tj ET Q q 0 0 0 rg BT 91.82 228.25 Td (funds, ) Tj ET Q q 0 0 0 rg BT 118.70 228.25 Td (fixed ) Tj ET Q q 0 0 0 rg BT 141.40 228.25 Td (income ) Tj ET Q q 0 0 0 rg BT 172.99 228.25 Td (funds, ) Tj ET Q q 0 0 0 rg BT 199.86 228.25 Td (and ) Tj ET Q q 0 0 0 rg BT 216.46 228.25 Td (short-term ) Tj ET Q q 0 0 0 rg BT 260.27 228.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 306.30 228.25 Td (funds ) Tj ET Q q 0 0 0 rg BT 330.68 228.25 Td (classified ) Tj ET Q q 0 0 0 rg BT 370.60 228.25 Td (as ) Tj ET Q q 0 0 0 rg BT 381.08 228.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 406.00 228.25 Td (2 ) Tj ET Q q 0 0 0 rg BT 413.16 228.25 Td (within ) Tj ET Q q 0 0 0 rg BT 440.87 228.25 Td (the ) Tj ET Q q 0 0 0 rg BT 455.24 228.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 471.27 228.25 Td (value ) Tj ET Q q 0 0 0 rg BT 495.08 228.25 Td (hierarchy ) Tj ET Q q 0 0 0 rg BT 534.99 228.25 Td (are ) Tj ET Q q 0 0 0 rg BT 549.35 228.25 Td (valued ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 216.25 Td (at ) Tj ET Q q 0 0 0 rg BT 72.51 216.25 Td (the ) Tj ET Q q 0 0 0 rg BT 87.01 216.25 Td (net ) Tj ET Q q 0 0 0 rg BT 101.52 216.25 Td (asset ) Tj ET Q q 0 0 0 rg BT 123.25 216.25 Td (value ) Tj ET Q q 0 0 0 rg BT 147.19 216.25 Td (of ) Tj ET Q q 0 0 0 rg BT 157.81 216.25 Td (their ) Tj ET Q q 0 0 0 rg BT 178.43 216.25 Td (shares ) Tj ET Q q 0 0 0 rg BT 205.71 216.25 Td (held ) Tj ET Q q 0 0 0 rg BT 225.22 216.25 Td (at ) Tj ET Q q 0 0 0 rg BT 234.72 216.25 Td (year ) Tj ET Q q 0 0 0 rg BT 254.22 216.25 Td (end, ) Tj ET Q q 0 0 0 rg BT 273.45 216.25 Td (which ) Tj ET Q q 0 0 0 rg BT 300.18 216.25 Td (represents ) Tj ET Q q 0 0 0 rg BT 343.00 216.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 359.17 216.25 Td (value. ) Tj ET Q q 0 0 0 rg BT 385.62 216.25 Td (Corporate ) Tj ET Q q 0 0 0 rg BT 427.89 216.25 Td (debt ) Tj ET Q q 0 0 0 rg BT 447.40 216.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 487.45 216.25 Td (and ) Tj ET Q q 0 0 0 rg BT 504.18 216.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 524.09 216.25 Td (T) Tj ET Q q 0 0 0 rg BT 529.85 216.25 Td (reasury ) Tj ET Q q 0 0 0 rg BT 561.56 216.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 204.25 Td (agency ) Tj ET Q q 0 0 0 rg BT 93.34 204.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 133.14 204.25 Td (classified ) Tj ET Q q 0 0 0 rg BT 172.93 204.25 Td (as ) Tj ET Q q 0 0 0 rg BT 183.29 204.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 208.08 204.25 Td (2 ) Tj ET Q q 0 0 0 rg BT 215.11 204.25 Td (within ) Tj ET Q q 0 0 0 rg BT 242.69 204.25 Td (the ) Tj ET Q q 0 0 0 rg BT 256.94 204.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 272.85 204.25 Td (value ) Tj ET Q q 0 0 0 rg BT 296.53 204.25 Td (hierarchy ) Tj ET Q q 0 0 0 rg BT 336.31 204.25 Td (are ) Tj ET Q q 0 0 0 rg BT 350.55 204.25 Td (valued ) Tj ET Q q 0 0 0 rg BT 379.23 204.25 Td (utilizing ) Tj ET Q q 0 0 0 rg BT 414.59 204.25 Td (observable ) Tj ET Q q 0 0 0 rg BT 459.94 204.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 485.84 204.25 Td (for ) Tj ET Q q 0 0 0 rg BT 499.53 204.25 Td (similar ) Tj ET Q q 0 0 0 rg BT 529.33 204.25 Td (instruments ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 192.25 Td (and ) Tj ET Q q 0 0 0 rg BT 79.94 192.25 Td (quoted ) Tj ET Q q 0 0 0 rg BT 109.66 192.25 Td (prices ) Tj ET Q q 0 0 0 rg BT 136.03 192.25 Td (for ) Tj ET Q q 0 0 0 rg BT 150.19 192.25 Td (identical ) Tj ET Q q 0 0 0 rg BT 187.12 192.25 Td (or ) Tj ET Q q 0 0 0 rg BT 197.95 192.25 Td (similar ) Tj ET Q q 0 0 0 rg BT 228.22 192.25 Td (instruments ) Tj ET Q q 0 0 0 rg BT 277.39 192.25 Td (in ) Tj ET Q q 0 0 0 rg BT 287.67 192.25 Td (markets ) Tj ET Q q 0 0 0 rg BT 321.82 192.25 Td (that ) Tj ET Q q 0 0 0 rg BT 339.32 192.25 Td (are ) Tj ET Q q 0 0 0 rg BT 354.03 192.25 Td (not ) Tj ET Q q 0 0 0 rg BT 369.30 192.25 Td (active.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 175.25 Td (Level ) Tj ET Q q 0 0 0 rg BT 88.69 175.25 Td (3 ) Tj ET Q q 0 0 0 rg BT 96.61 175.25 Td (unobservable ) Tj ET Q q 0 0 0 rg BT 152.85 175.25 Td (inputs ) Tj ET Q q 0 0 0 rg BT 180.22 175.25 Td (are ) Tj ET Q q 0 0 0 rg BT 195.35 175.25 Td (used ) Tj ET Q q 0 0 0 rg BT 216.61 175.25 Td (when ) Tj ET Q q 0 0 0 rg BT 241.19 175.25 Td (little ) Tj ET Q q 0 0 0 rg BT 262.45 175.25 Td (or ) Tj ET Q q 0 0 0 rg BT 273.70 175.25 Td (no ) Tj ET Q q 0 0 0 rg BT 286.62 175.25 Td (market ) Tj ET Q q 0 0 0 rg BT 317.31 175.25 Td (data ) Tj ET Q q 0 0 0 rg BT 336.89 175.25 Td (is ) Tj ET Q q 0 0 0 rg BT 346.48 175.25 Td (available. ) Tj ET Q q 0 0 0 rg BT 388.00 175.25 Td (Insurance ) Tj ET Q q 0 0 0 rg BT 429.79 175.25 Td (contracts ) Tj ET Q q 0 0 0 rg BT 468.80 175.25 Td (are ) Tj ET Q q 0 0 0 rg BT 483.94 175.25 Td (held ) Tj ET Q q 0 0 0 rg BT 504.08 175.25 Td (by ) Tj ET Q q 0 0 0 rg BT 517.00 175.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 547.13 175.25 Td (foreign ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 163.25 Td (pension ) Tj ET Q q 0 0 0 rg BT 96.67 163.25 Td (plans ) Tj ET Q q 0 0 0 rg BT 120.33 163.25 Td (and ) Tj ET Q q 0 0 0 rg BT 137.33 163.25 Td (are ) Tj ET Q q 0 0 0 rg BT 152.09 163.25 Td (carried ) Tj ET Q q 0 0 0 rg BT 182.40 163.25 Td (at ) Tj ET Q q 0 0 0 rg BT 192.18 163.25 Td (contract ) Tj ET Q q 0 0 0 rg BT 226.94 163.25 Td (value, ) Tj ET Q q 0 0 0 rg BT 253.65 163.25 Td (which ) Tj ET Q q 0 0 0 rg BT 280.65 163.25 Td (approximates ) Tj ET Q q 0 0 0 rg BT 337.08 163.25 Td (the ) Tj ET Q q 0 0 0 rg BT 351.85 163.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 392.73 163.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 409.16 163.25 Td (value ) Tj ET Q q 0 0 0 rg BT 433.38 163.25 Td (and ) Tj ET Q q 0 0 0 rg BT 450.37 163.25 Td (is ) Tj ET Q q 0 0 0 rg BT 459.60 163.25 Td (based ) Tj ET Q q 0 0 0 rg BT 484.93 163.25 Td (on ) Tj ET Q q 0 0 0 rg BT 497.48 163.25 Td (the ) Tj ET Q q 0 0 0 rg BT 512.26 163.25 Td (fair ) Tj ET Q q 0 0 0 rg BT 528.69 163.25 Td (value ) Tj ET Q q 0 0 0 rg BT 552.91 163.25 Td (of ) Tj ET Q q 0 0 0 rg BT 563.79 163.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 63.00 151.25 Td (underlying ) Tj ET Q q 0 0 0 rg BT 108.83 151.25 Td (investment ) Tj ET Q q 0 0 0 rg BT 155.21 151.25 Td (of ) Tj ET Q q 0 0 0 rg BT 166.04 151.25 Td (the ) Tj ET Q q 0 0 0 rg BT 180.75 151.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 221.57 151.25 Td (company) Tj ET Q q 0 0 0 rg BT 257.58 151.25 Td (. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 130.25 Td (V) Tj ET Q q 0 0 0 rg BT 42.11 130.25 Td (enture ) Tj ET Q q 0 0 0 rg BT 68.81 130.25 Td (capital ) Tj ET Q q 0 0 0 rg BT 97.17 130.25 Td (and ) Tj ET Q q 0 0 0 rg BT 113.32 130.25 Td (limited ) Tj ET Q q 0 0 0 rg BT 143.36 130.25 Td (partnership ) Tj ET Q q 0 0 0 rg BT 190.06 130.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 239.54 130.25 Td (are ) Tj ET Q q 0 0 0 rg BT 253.46 130.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 290.16 130.25 Td (only ) Tj ET Q q 0 0 0 rg BT 309.65 130.25 Td (redeemable ) Tj ET Q q 0 0 0 rg BT 357.44 130.25 Td (through ) Tj ET Q q 0 0 0 rg BT 390.25 130.25 Td (distributions ) Tj ET Q q 0 0 0 rg BT 441.97 130.25 Td (upon ) Tj ET Q q 0 0 0 rg BT 463.68 130.25 Td (liquidation ) Tj ET Q q 0 0 0 rg BT 508.72 130.25 Td (of ) Tj ET Q q 0 0 0 rg BT 518.76 130.25 Td (the ) Tj ET Q q 0 0 0 rg BT 532.69 130.25 Td (underlying ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 118.25 Td (assets. ) Tj ET Q q 0 0 0 rg BT 64.18 118.25 Td (There ) Tj ET Q q 0 0 0 rg BT 90.03 118.25 Td (were ) Tj ET Q q 0 0 0 rg BT 111.99 118.25 Td (no ) Tj ET Q q 0 0 0 rg BT 124.53 118.25 Td (significant ) Tj ET Q q 0 0 0 rg BT 169.27 118.25 Td (unfunded ) Tj ET Q q 0 0 0 rg BT 209.58 118.25 Td (commitments ) Tj ET Q q 0 0 0 rg BT 266.55 118.25 Td (for ) Tj ET Q q 0 0 0 rg BT 280.74 118.25 Td (these ) Tj ET Q q 0 0 0 rg BT 303.82 118.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 354.13 118.25 Td (and ) Tj ET Q q 0 0 0 rg BT 371.10 118.25 Td (essentially ) Tj ET Q q 0 0 0 rg BT 415.85 118.25 Td (all ) Tj ET Q q 0 0 0 rg BT 428.38 118.25 Td (liquidations ) Tj ET Q q 0 0 0 rg BT 478.14 118.25 Td (are ) Tj ET Q q 0 0 0 rg BT 492.88 118.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 530.94 118.25 Td (to ) Tj ET Q q 0 0 0 rg BT 541.26 118.25 Td (occur ) Tj ET Q q 0 0 0 rg BT 566.00 118.25 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 106.25 Td (2019. Most ) Tj ET Q q 0 0 0 rg BT 84.06 106.25 Td (of ) Tj ET Q q 0 0 0 rg BT 94.89 106.25 Td (the ) Tj ET Q q 0 0 0 rg BT 109.61 106.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 152.65 106.25 Td (investments ) Tj ET Q q 0 0 0 rg BT 202.92 106.25 Td (using ) Tj ET Q q 0 0 0 rg BT 227.09 106.25 Td (the ) Tj ET Q q 0 0 0 rg BT 241.81 106.25 Td (practical ) Tj ET Q q 0 0 0 rg BT 278.73 106.25 Td (expedient ) Tj ET Q q 0 0 0 rg BT 320.10 106.25 Td (are ) Tj ET Q q 0 0 0 rg BT 334.81 106.25 Td (redeemable ) Tj ET Q q 0 0 0 rg BT 383.39 106.25 Td (on ) Tj ET Q q 0 0 0 rg BT 395.89 106.25 Td (a ) Tj ET Q q 0 0 0 rg BT 402.83 106.25 Td (weekly ) Tj ET Q q 0 0 0 rg BT 434.20 106.25 Td (or ) Tj ET Q q 0 0 0 rg BT 445.03 106.25 Td (monthly ) Tj ET Q q 0 0 0 rg BT 480.87 106.25 Td (basis.) Tj ET Q endstream endobj 193 0 obj <> endobj 194 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (96) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.40 749.10 Td (investment ) Tj ET Q q 0 0 0 rg BT 101.14 749.10 Td (strategy ) Tj ET Q q 0 0 0 rg BT 135.65 749.10 Td (is ) Tj ET Q q 0 0 0 rg BT 145.17 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 155.80 749.10 Td (maximize ) Tj ET Q q 0 0 0 rg BT 198.08 749.10 Td (return ) Tj ET Q q 0 0 0 rg BT 224.82 749.10 Td (while ) Tj ET Q q 0 0 0 rg BT 249.89 749.10 Td (maintaining ) Tj ET Q q 0 0 0 rg BT 300.51 749.10 Td (an ) Tj ET Q q 0 0 0 rg BT 312.80 749.10 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 361.19 749.10 Td (level ) Tj ET Q q 0 0 0 rg BT 383.48 749.10 Td (of ) Tj ET Q q 0 0 0 rg BT 394.66 749.10 Td (risk ) Tj ET Q q 0 0 0 rg BT 412.51 749.10 Td (to ) Tj ET Q q 0 0 0 rg BT 423.15 749.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 456.55 749.10 Td (suf) Tj ET Q q 0 0 0 rg BT 468.59 749.10 Td (ficient ) Tj ET Q q 0 0 0 rg BT 496.98 749.10 Td (liquidity ) Tj ET Q q 0 0 0 rg BT 533.73 749.10 Td (for ) Tj ET Q q 0 0 0 rg BT 548.24 749.10 Td (benefit ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 737.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 82.61 737.10 Td (and ) Tj ET Q q 0 0 0 rg BT 99.22 737.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 118.60 737.10 Td (expenses. ) Tj ET Q q 0 0 0 rg BT 159.37 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 161.06 737.10 Td (A) Tj ET Q q 0 0 0 rg BT 167.73 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 169.90 737.10 Td (tar) Tj ET Q q 0 0 0 rg BT 180.26 737.10 Td (get ) Tj ET Q q 0 0 0 rg BT 194.65 737.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 216.25 737.10 Td (allocation ) Tj ET Q q 0 0 0 rg BT 257.85 737.10 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.35 737.10 Td (43%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 286.68 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 288.85 737.10 Td (public ) Tj ET Q q 0 0 0 rg BT 316.01 737.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 343.17 737.10 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 346.50 737.10 Td (16%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 364.83 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 367.00 737.10 Td (international, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.21 737.10 Td (14%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 440.54 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 442.70 737.10 Td (global ) Tj ET Q q 0 0 0 rg BT 469.87 737.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.47 737.10 Td (13%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.80 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 506.97 737.10 Td (U.S.\), ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.75 737.10 Td (7%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 546.08 737.10 Td ( ) Tj ET Q q 0 0 0 rg BT 548.25 737.10 Td (private ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 725.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 63.13 725.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 79.70 725.10 Td (50%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 98.03 725.10 Td ( ) Tj ET Q q 0 0 0 rg BT 100.16 725.10 Td (long-duration ) Tj ET Q q 0 0 0 rg BT 156.73 725.10 Td (fixed ) Tj ET Q q 0 0 0 rg BT 179.41 725.10 Td (income ) Tj ET Q q 0 0 0 rg BT 210.97 725.10 Td (is ) Tj ET Q q 0 0 0 rg BT 219.78 725.10 Td (maintained ) Tj ET Q q 0 0 0 rg BT 266.34 725.10 Td (for ) Tj ET Q q 0 0 0 rg BT 280.13 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 294.48 725.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 314.40 725.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 347.64 725.10 Td (plans. ) Tj ET Q q 0 0 0 rg BT 373.38 725.10 Td (Investments ) Tj ET Q q 0 0 0 rg BT 423.84 725.10 Td (are ) Tj ET Q q 0 0 0 rg BT 438.18 725.10 Td (diversified ) Tj ET Q q 0 0 0 rg BT 483.07 725.10 Td (within ) Tj ET Q q 0 0 0 rg BT 510.76 725.10 Td (each ) Tj ET Q q 0 0 0 rg BT 531.21 725.10 Td (of ) Tj ET Q q 0 0 0 rg BT 541.67 725.10 Td (the ) Tj ET Q q 0 0 0 rg BT 556.02 725.10 Td (three ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 713.10 Td (major ) Tj ET Q q 0 0 0 rg BT 62.45 713.10 Td (asset ) Tj ET Q q 0 0 0 rg BT 85.00 713.10 Td (categories. ) Tj ET Q q 0 0 0 rg BT 130.47 713.10 Td (Approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 194.13 713.10 Td (90%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 212.46 713.10 Td ( ) Tj ET Q q 0 0 0 rg BT 215.58 713.10 Td (of ) Tj ET Q q 0 0 0 rg BT 227.03 713.10 Td (the ) Tj ET Q q 0 0 0 rg BT 242.37 713.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 263.27 713.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 297.50 713.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 321.73 713.10 Td (equity ) Tj ET Q q 0 0 0 rg BT 349.84 713.10 Td (investments ) Tj ET Q q 0 0 0 rg BT 400.74 713.10 Td (are ) Tj ET Q q 0 0 0 rg BT 416.06 713.10 Td (actively ) Tj ET Q q 0 0 0 rg BT 450.83 713.10 Td (managed. ) Tj ET Q q 0 0 0 rg BT 492.55 713.10 Td (BMS ) Tj ET Q q 0 0 0 rg BT 516.79 713.10 Td (common ) Tj ET Q q 0 0 0 rg BT 554.91 713.10 Td (stock ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 701.10 Td (represents ) Tj ET Q q 0 0 0 rg BT 79.04 701.10 Td (less ) Tj ET Q q 0 0 0 rg BT 96.54 701.10 Td (than ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 116.25 701.10 Td (1%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 129.58 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 132.08 701.10 Td (of ) Tj ET Q q 0 0 0 rg BT 142.91 701.10 Td (the ) Tj ET Q q 0 0 0 rg BT 157.63 701.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 177.35 701.10 Td (assets ) Tj ET Q q 0 0 0 rg BT 203.18 701.10 Td (at ) Tj ET Q q 0 0 0 rg BT 212.89 701.10 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 271.48 701.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 291.48 701.10 Td ( ) Tj ET Q q 0 0 0 rg BT 293.98 701.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 310.92 701.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 330.92 701.10 Td (.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 677.10 Td (Contributions and Estimated Futur) Tj ET Q q 0 0 0 rg BT 176.47 677.10 Td (e Benefit Payments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.10 Td (Contributions ) Tj ET Q q 0 0 0 rg BT 94.85 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 106.47 653.10 Td (pension ) Tj ET Q q 0 0 0 rg BT 141.43 653.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 166.38 653.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 189.65 653.10 Td ($396 ) Tj ET Q q 0 0 0 rg BT 213.50 653.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 242.39 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 246.24 653.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 257.86 653.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 277.86 653.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 284.21 653.10 Td ($81 ) Tj ET Q q 0 0 0 rg BT 303.05 653.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 331.94 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 335.79 653.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 347.41 653.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 367.41 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 371.26 653.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 389.54 653.10 Td ($1) Tj ET Q q 0 0 0 rg BT 399.17 653.10 Td (18 ) Tj ET Q q 0 0 0 rg BT 413.01 653.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.91 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 445.75 653.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.37 653.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.37 653.10 Td ( ) Tj ET Q q 0 0 0 rg BT 481.22 653.10 Td (and ) Tj ET Q q 0 0 0 rg BT 499.50 653.10 Td (are ) Tj ET Q q 0 0 0 rg BT 515.56 653.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 554.93 653.10 Td (to ) Tj ET Q q 0 0 0 rg BT 566.56 653.10 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 95.76 641.10 Td ($70 ) Tj ET Q q 0 0 0 rg BT 112.77 641.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 141.66 641.10 Td ( ) Tj ET Q q 0 0 0 rg BT 143.66 641.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 153.45 641.10 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 173.45 641.10 Td (. ) Tj ET Q q 0 0 0 rg BT 177.95 641.10 Td (Estimated ) Tj ET Q q 0 0 0 rg BT 219.95 641.10 Td (annual ) Tj ET Q q 0 0 0 rg BT 248.60 641.10 Td (future ) Tj ET Q q 0 0 0 rg BT 274.49 641.10 Td (benefit ) Tj ET Q q 0 0 0 rg BT 304.25 641.10 Td (payments ) Tj ET Q q 0 0 0 rg BT 344.58 641.10 Td (\(including ) Tj ET Q q 0 0 0 rg BT 387.69 641.10 Td (lump ) Tj ET Q q 0 0 0 rg BT 410.25 641.10 Td (sum ) Tj ET Q q 0 0 0 rg BT 428.93 641.10 Td (payments\) ) Tj ET Q q 0 0 0 rg BT 472.59 641.10 Td (range ) Tj ET Q q 0 0 0 rg BT 496.80 641.10 Td (from ) Tj ET Q q 0 0 0 rg BT 518.24 641.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.10 Td ($275 ) Tj ET Q q 0 0 0 rg BT 58.50 629.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.39 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 89.89 629.10 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 100.17 629.10 Td ($300 ) Tj ET Q q 0 0 0 rg BT 122.67 629.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 151.56 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 154.06 629.10 Td (in ) Tj ET Q q 0 0 0 rg BT 164.34 629.10 Td (each ) Tj ET Q q 0 0 0 rg BT 185.16 629.10 Td (of ) Tj ET Q q 0 0 0 rg BT 195.99 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 210.70 629.10 Td (next ) Tj ET Q q 0 0 0 rg BT 230.42 629.10 Td (five ) Tj ET Q q 0 0 0 rg BT 248.47 629.10 Td (years, ) Tj ET Q q 0 0 0 rg BT 274.56 629.10 Td (and ) Tj ET Q q 0 0 0 rg BT 291.50 629.10 Td (aggregate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.87 629.10 Td ($1.6 ) Tj ET Q q 0 0 0 rg BT 352.87 629.10 Td (billion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 378.98 629.10 Td ( ) Tj ET Q q 0 0 0 rg BT 381.48 629.10 Td (in ) Tj ET Q q 0 0 0 rg BT 391.76 629.10 Td (the ) Tj ET Q q 0 0 0 rg BT 406.47 629.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 453.41 629.10 Td (five ) Tj ET Q q 0 0 0 rg BT 471.46 629.10 Td (year ) Tj ET Q q 0 0 0 rg BT 491.17 629.10 Td (period.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 605.10 Td (Savings Plans) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.10 Td (The ) Tj ET Q q 0 0 0 rg BT 54.98 581.10 Td (principal ) Tj ET Q q 0 0 0 rg BT 93.96 581.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 127.38 581.10 Td (contribution ) Tj ET Q q 0 0 0 rg BT 179.70 581.10 Td (plan ) Tj ET Q q 0 0 0 rg BT 200.35 581.10 Td (is ) Tj ET Q q 0 0 0 rg BT 210.45 581.10 Td (the ) Tj ET Q q 0 0 0 rg BT 226.10 581.10 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 285.65 581.10 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 317.42 581.10 Td (Savings ) Tj ET Q q 0 0 0 rg BT 352.53 581.10 Td (and ) Tj ET Q q 0 0 0 rg BT 370.40 581.10 Td (Investment ) Tj ET Q q 0 0 0 rg BT 418.27 581.10 Td (Program. ) Tj ET Q q 0 0 0 rg BT 458.40 581.10 Td (The ) Tj ET Q q 0 0 0 rg BT 477.38 581.10 Td (contribution ) Tj ET Q q 0 0 0 rg BT 529.69 581.10 Td (is ) Tj ET Q q 0 0 0 rg BT 539.80 581.10 Td (based ) Tj ET Q q 0 0 0 rg BT 566.00 581.10 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.10 Td (employee ) Tj ET Q q 0 0 0 rg BT 79.39 569.10 Td (contributions ) Tj ET Q q 0 0 0 rg BT 136.68 569.10 Td (and ) Tj ET Q q 0 0 0 rg BT 155.63 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 172.36 569.10 Td (level ) Tj ET Q q 0 0 0 rg BT 196.31 569.10 Td (of ) Tj ET Q q 0 0 0 rg BT 209.16 569.10 Td (Company ) Tj ET Q q 0 0 0 rg BT 252.56 569.10 Td (match. ) Tj ET Q q 0 0 0 rg BT 283.68 569.10 Td (The ) Tj ET Q q 0 0 0 rg BT 303.75 569.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 340.47 569.10 Td (attributed ) Tj ET Q q 0 0 0 rg BT 383.30 569.10 Td (to ) Tj ET Q q 0 0 0 rg BT 395.60 569.10 Td (defined ) Tj ET Q q 0 0 0 rg BT 430.10 569.10 Td (contribution ) Tj ET Q q 0 0 0 rg BT 483.50 569.10 Td (plans ) Tj ET Q q 0 0 0 rg BT 509.12 569.10 Td (in ) Tj ET Q q 0 0 0 rg BT 521.42 569.10 Td (the ) Tj ET Q q 0 0 0 rg BT 538.15 569.10 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 560.45 569.10 Td (was ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.10 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 96.26 557.10 Td ($200 ) Tj ET Q q 0 0 0 rg BT 118.76 557.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 147.65 557.10 Td ( ) Tj ET Q q 0 0 0 rg BT 150.15 557.10 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 160.43 557.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 180.43 557.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 185.43 557.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.43 557.10 Td ( ) Tj ET Q q 0 0 0 rg BT 207.93 557.10 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 224.87 557.10 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 244.87 557.10 Td (.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 531.10 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 531.10 Td (17) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 531.10 Td (. EMPLOYEE ST) Tj ET Q q 0 0 0 rg BT 145.27 531.10 Td (OCK BENEFIT) Tj ET Q q 0 0 0 rg BT 214.27 531.10 Td ( PLANS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 514.10 Td (On ) Tj ET Q q 0 0 0 rg BT 50.94 514.10 Td (May ) Tj ET Q q 0 0 0 rg BT 71.98 514.10 Td (1, ) Tj ET Q q 0 0 0 rg BT 82.19 514.10 Td (2012, ) Tj ET Q q 0 0 0 rg BT 107.41 514.10 Td (the ) Tj ET Q q 0 0 0 rg BT 122.34 514.10 Td (shareholders ) Tj ET Q q 0 0 0 rg BT 175.59 514.10 Td (approved ) Tj ET Q q 0 0 0 rg BT 215.51 514.10 Td (the ) Tj ET Q q 0 0 0 rg BT 230.44 514.10 Td (2012 ) Tj ET Q q 0 0 0 rg BT 253.15 514.10 Td (Plan, ) Tj ET Q q 0 0 0 rg BT 276.15 514.10 Td (which ) Tj ET Q q 0 0 0 rg BT 303.30 514.10 Td (replaced ) Tj ET Q q 0 0 0 rg BT 339.88 514.10 Td (the ) Tj ET Q q 0 0 0 rg BT 354.81 514.10 Td (2007 ) Tj ET Q q 0 0 0 rg BT 377.52 514.10 Td (Stock ) Tj ET Q q 0 0 0 rg BT 403.01 514.10 Td (Incentive ) Tj ET Q q 0 0 0 rg BT 442.93 514.10 Td (Plan. ) Tj ET Q q 0 0 0 rg BT 465.72 514.10 Td (The ) Tj ET Q q 0 0 0 rg BT 483.98 514.10 Td (2012 ) Tj ET Q q 0 0 0 rg BT 506.70 514.10 Td (Plan ) Tj ET Q q 0 0 0 rg BT 527.19 514.10 Td (provides ) Tj ET Q q 0 0 0 rg BT 564.34 514.10 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 502.10 Td (109 ) Tj ET Q q 0 0 0 rg BT 53.15 502.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 82.05 502.10 Td ( ) Tj ET Q q 0 0 0 rg BT 84.20 502.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 111.35 502.10 Td (to ) Tj ET Q q 0 0 0 rg BT 121.28 502.10 Td (be ) Tj ET Q q 0 0 0 rg BT 132.87 502.10 Td (authorized ) Tj ET Q q 0 0 0 rg BT 177.23 502.10 Td (for ) Tj ET Q q 0 0 0 rg BT 191.04 502.10 Td (grants, ) Tj ET Q q 0 0 0 rg BT 220.14 502.10 Td (plus ) Tj ET Q q 0 0 0 rg BT 238.96 502.10 Td (any ) Tj ET Q q 0 0 0 rg BT 255.56 502.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 282.70 502.10 Td (from ) Tj ET Q q 0 0 0 rg BT 304.29 502.10 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 353.11 502.10 Td (awards ) Tj ET Q q 0 0 0 rg BT 383.59 502.10 Td (under ) Tj ET Q q 0 0 0 rg BT 408.51 502.10 Td (the ) Tj ET Q q 0 0 0 rg BT 422.88 502.10 Td (2007 ) Tj ET Q q 0 0 0 rg BT 445.04 502.10 Td (Plan ) Tj ET Q q 0 0 0 rg BT 464.97 502.10 Td (as ) Tj ET Q q 0 0 0 rg BT 475.46 502.10 Td (of ) Tj ET Q q 0 0 0 rg BT 485.94 502.10 Td (February ) Tj ET Q q 0 0 0 rg BT 524.19 502.10 Td (29, ) Tj ET Q q 0 0 0 rg BT 538.85 502.10 Td (2012 ) Tj ET Q q 0 0 0 rg BT 561.00 502.10 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 490.10 Td (expire, ) Tj ET Q q 0 0 0 rg BT 66.57 490.10 Td (are ) Tj ET Q q 0 0 0 rg BT 81.86 490.10 Td (forfeited, ) Tj ET Q q 0 0 0 rg BT 121.87 490.10 Td (canceled, ) Tj ET Q q 0 0 0 rg BT 162.43 490.10 Td (or ) Tj ET Q q 0 0 0 rg BT 173.85 490.10 Td (withheld ) Tj ET Q q 0 0 0 rg BT 211.93 490.10 Td (to ) Tj ET Q q 0 0 0 rg BT 222.79 490.10 Td (satisfy ) Tj ET Q q 0 0 0 rg BT 251.99 490.10 Td (tax ) Tj ET Q q 0 0 0 rg BT 267.29 490.10 Td (withholding ) Tj ET Q q 0 0 0 rg BT 318.71 490.10 Td (obligations. ) Tj ET Q q 0 0 0 rg BT 368.06 490.10 Td (As ) Tj ET Q q 0 0 0 rg BT 382.26 490.10 Td (of ) Tj ET Q q 0 0 0 rg BT 393.67 490.10 Td (December 31, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.84 490.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.84 490.10 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 478.43 490.10 Td (104 ) Tj ET Q q 0 0 0 rg BT 496.52 490.10 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.41 490.10 Td ( ) Tj ET Q q 0 0 0 rg BT 528.49 490.10 Td (shares ) Tj ET Q q 0 0 0 rg BT 556.57 490.10 Td (were ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 478.10 Td (available ) Tj ET Q q 0 0 0 rg BT 74.59 478.10 Td (for ) Tj ET Q q 0 0 0 rg BT 88.75 478.10 Td (award. ) Tj ET Q q 0 0 0 rg BT 118.18 478.10 Td (Shares ) Tj ET Q q 0 0 0 rg BT 147.34 478.10 Td (are ) Tj ET Q q 0 0 0 rg BT 162.04 478.10 Td (issued ) Tj ET Q q 0 0 0 rg BT 189.54 478.10 Td (from ) Tj ET Q q 0 0 0 rg BT 211.48 478.10 Td (treasury ) Tj ET Q q 0 0 0 rg BT 246.19 478.10 Td (stock ) Tj ET Q q 0 0 0 rg BT 269.80 478.10 Td (to ) Tj ET Q q 0 0 0 rg BT 280.08 478.10 Td (satisfy ) Tj ET Q q 0 0 0 rg BT 308.69 478.10 Td (our ) Tj ET Q q 0 0 0 rg BT 324.52 478.10 Td (obligations ) Tj ET Q q 0 0 0 rg BT 371.46 478.10 Td (under ) Tj ET Q q 0 0 0 rg BT 396.73 478.10 Td (this ) Tj ET Q q 0 0 0 rg BT 413.68 478.10 Td (Plan.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 456.50 Td (Executive ) Tj ET Q q 0 0 0 rg BT 78.24 456.50 Td (of) Tj ET Q q 0 0 0 rg BT 86.39 456.50 Td (ficers ) Tj ET Q q 0 0 0 rg BT 110.86 456.50 Td (and ) Tj ET Q q 0 0 0 rg BT 127.56 456.50 Td (key ) Tj ET Q q 0 0 0 rg BT 144.26 456.50 Td (employees ) Tj ET Q q 0 0 0 rg BT 189.29 456.50 Td (may ) Tj ET Q q 0 0 0 rg BT 208.77 456.50 Td (be ) Tj ET Q q 0 0 0 rg BT 220.47 456.50 Td (granted ) Tj ET Q q 0 0 0 rg BT 252.72 456.50 Td (options ) Tj ET Q q 0 0 0 rg BT 284.43 456.50 Td (to ) Tj ET Q q 0 0 0 rg BT 294.47 456.50 Td (purchase ) Tj ET Q q 0 0 0 rg BT 332.27 456.50 Td (common ) Tj ET Q q 0 0 0 rg BT 369.52 456.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 392.89 456.50 Td (at ) Tj ET Q q 0 0 0 rg BT 402.37 456.50 Td (no ) Tj ET Q q 0 0 0 rg BT 414.64 456.50 Td (less ) Tj ET Q q 0 0 0 rg BT 431.90 456.50 Td (than ) Tj ET Q q 0 0 0 rg BT 451.38 456.50 Td (the ) Tj ET Q q 0 0 0 rg BT 465.86 456.50 Td (market ) Tj ET Q q 0 0 0 rg BT 495.88 456.50 Td (price ) Tj ET Q q 0 0 0 rg BT 518.13 456.50 Td (on ) Tj ET Q q 0 0 0 rg BT 530.39 456.50 Td (the ) Tj ET Q q 0 0 0 rg BT 544.87 456.50 Td (date ) Tj ET Q q 0 0 0 rg BT 563.79 456.50 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 444.50 Td (option ) Tj ET Q q 0 0 0 rg BT 63.42 444.50 Td (is ) Tj ET Q q 0 0 0 rg BT 71.96 444.50 Td (granted. ) Tj ET Q q 0 0 0 rg BT 106.31 444.50 Td (Options ) Tj ET Q q 0 0 0 rg BT 139.85 444.50 Td (generally ) Tj ET Q q 0 0 0 rg BT 178.92 444.50 Td (become ) Tj ET Q q 0 0 0 rg BT 211.88 444.50 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 258.72 444.50 Td (ratably ) Tj ET Q q 0 0 0 rg BT 288.35 444.50 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 307.99 444.50 Td (four) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 324.65 444.50 Td ( ) Tj ET Q q 0 0 0 rg BT 326.52 444.50 Td (years ) Tj ET Q q 0 0 0 rg BT 349.48 444.50 Td (and ) Tj ET Q q 0 0 0 rg BT 365.79 444.50 Td (have ) Tj ET Q q 0 0 0 rg BT 386.53 444.50 Td (a ) Tj ET Q q 0 0 0 rg BT 392.84 444.50 Td (maximum ) Tj ET Q q 0 0 0 rg BT 435.26 444.50 Td (term ) Tj ET Q q 0 0 0 rg BT 455.45 444.50 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.65 444.50 Td (ten) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 477.87 444.50 Td ( ) Tj ET Q q 0 0 0 rg BT 479.74 444.50 Td (years. ) Tj ET Q q 0 0 0 rg BT 505.07 444.50 Td (The ) Tj ET Q q 0 0 0 rg BT 522.48 444.50 Td (plan ) Tj ET Q q 0 0 0 rg BT 541.57 444.50 Td (provides ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 432.50 Td (for ) Tj ET Q q 0 0 0 rg BT 49.75 432.50 Td (the ) Tj ET Q q 0 0 0 rg BT 64.05 432.50 Td (granting ) Tj ET Q q 0 0 0 rg BT 99.46 432.50 Td (of ) Tj ET Q q 0 0 0 rg BT 109.88 432.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 133.08 432.50 Td (appreciation ) Tj ET Q q 0 0 0 rg BT 184.58 432.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 209.45 432.50 Td (whereby ) Tj ET Q q 0 0 0 rg BT 245.97 432.50 Td (the ) Tj ET Q q 0 0 0 rg BT 260.27 432.50 Td (grantee ) Tj ET Q q 0 0 0 rg BT 291.78 432.50 Td (may ) Tj ET Q q 0 0 0 rg BT 311.09 432.50 Td (surrender ) Tj ET Q q 0 0 0 rg BT 350.93 432.50 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 397.99 432.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 422.86 432.50 Td (and ) Tj ET Q q 0 0 0 rg BT 439.38 432.50 Td (receive ) Tj ET Q q 0 0 0 rg BT 470.33 432.50 Td (common ) Tj ET Q q 0 0 0 rg BT 507.41 432.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 530.61 432.50 Td (and/or ) Tj ET Q q 0 0 0 rg BT 558.24 432.50 Td (cash ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 420.50 Td (measured ) Tj ET Q q 0 0 0 rg BT 76.57 420.50 Td (by ) Tj ET Q q 0 0 0 rg BT 88.82 420.50 Td (the ) Tj ET Q q 0 0 0 rg BT 103.28 420.50 Td (excess ) Tj ET Q q 0 0 0 rg BT 131.63 420.50 Td (of ) Tj ET Q q 0 0 0 rg BT 142.21 420.50 Td (the ) Tj ET Q q 0 0 0 rg BT 156.68 420.50 Td (market ) Tj ET Q q 0 0 0 rg BT 186.69 420.50 Td (price ) Tj ET Q q 0 0 0 rg BT 208.93 420.50 Td (of ) Tj ET Q q 0 0 0 rg BT 219.51 420.50 Td (the ) Tj ET Q q 0 0 0 rg BT 233.97 420.50 Td (common ) Tj ET Q q 0 0 0 rg BT 271.22 420.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 294.58 420.50 Td (over ) Tj ET Q q 0 0 0 rg BT 314.60 420.50 Td (the ) Tj ET Q q 0 0 0 rg BT 329.06 420.50 Td (option ) Tj ET Q q 0 0 0 rg BT 356.87 420.50 Td (exercise ) Tj ET Q q 0 0 0 rg BT 391.87 420.50 Td (price. ) Tj ET Q q 0 0 0 rg BT 416.45 420.50 Td (The ) Tj ET Q q 0 0 0 rg BT 434.24 420.50 Td (Company ) Tj ET Q q 0 0 0 rg BT 475.38 420.50 Td (has ) Tj ET Q q 0 0 0 rg BT 490.96 420.50 Td (not ) Tj ET Q q 0 0 0 rg BT 505.99 420.50 Td (granted ) Tj ET Q q 0 0 0 rg BT 538.22 420.50 Td (any ) Tj ET Q q 0 0 0 rg BT 554.91 420.50 Td (stock ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 408.50 Td (options ) Tj ET Q q 0 0 0 rg BT 67.95 408.50 Td (or ) Tj ET Q q 0 0 0 rg BT 78.78 408.50 Td (stock ) Tj ET Q q 0 0 0 rg BT 102.39 408.50 Td (appreciation ) Tj ET Q q 0 0 0 rg BT 154.31 408.50 Td (rights ) Tj ET Q q 0 0 0 rg BT 179.58 408.50 Td (since ) Tj ET Q q 0 0 0 rg BT 202.63 408.50 Td (2009.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 386.90 Td (Restricted ) Tj ET Q q 0 0 0 rg BT 79.07 386.90 Td (stock ) Tj ET Q q 0 0 0 rg BT 102.71 386.90 Td (units ) Tj ET Q q 0 0 0 rg BT 124.68 386.90 Td (may ) Tj ET Q q 0 0 0 rg BT 144.43 386.90 Td (be ) Tj ET Q q 0 0 0 rg BT 156.40 386.90 Td (granted ) Tj ET Q q 0 0 0 rg BT 188.91 386.90 Td (to ) Tj ET Q q 0 0 0 rg BT 199.22 386.90 Td (key ) Tj ET Q q 0 0 0 rg BT 216.18 386.90 Td (employees, ) Tj ET Q q 0 0 0 rg BT 263.97 386.90 Td (subject ) Tj ET Q q 0 0 0 rg BT 294.83 386.90 Td (to ) Tj ET Q q 0 0 0 rg BT 305.13 386.90 Td (restrictions ) Tj ET Q q 0 0 0 rg BT 352.10 386.90 Td (as ) Tj ET Q q 0 0 0 rg BT 362.96 386.90 Td (to ) Tj ET Q q 0 0 0 rg BT 373.26 386.90 Td (continuous ) Tj ET Q q 0 0 0 rg BT 419.68 386.90 Td (employment. ) Tj ET Q q 0 0 0 rg BT 474.70 386.90 Td (Generally) Tj ET Q q 0 0 0 rg BT 513.47 386.90 Td (, ) Tj ET Q q 0 0 0 rg BT 518.50 386.90 Td (vesting ) Tj ET Q q 0 0 0 rg BT 549.91 386.90 Td (occurs ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 374.90 Td (ratably ) Tj ET Q q 0 0 0 rg BT 66.35 374.90 Td (over ) Tj ET Q q 0 0 0 rg BT 86.71 374.90 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 93.74 374.90 Td (four) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 110.40 374.90 Td ( ) Tj ET Q q 0 0 0 rg BT 112.99 374.90 Td (year ) Tj ET Q q 0 0 0 rg BT 132.78 374.90 Td (period ) Tj ET Q q 0 0 0 rg BT 160.92 374.90 Td (from ) Tj ET Q q 0 0 0 rg BT 182.95 374.90 Td (grant ) Tj ET Q q 0 0 0 rg BT 206.08 374.90 Td (date. ) Tj ET Q q 0 0 0 rg BT 227.26 374.90 Td (A) Tj ET Q q 0 0 0 rg BT 233.93 374.90 Td ( ) Tj ET Q q 0 0 0 rg BT 236.52 374.90 Td (stock ) Tj ET Q q 0 0 0 rg BT 260.21 374.90 Td (unit ) Tj ET Q q 0 0 0 rg BT 278.36 374.90 Td (is ) Tj ET Q q 0 0 0 rg BT 287.62 374.90 Td (a ) Tj ET Q q 0 0 0 rg BT 294.65 374.90 Td (right ) Tj ET Q q 0 0 0 rg BT 316.12 374.90 Td (to ) Tj ET Q q 0 0 0 rg BT 326.49 374.90 Td (receive ) Tj ET Q q 0 0 0 rg BT 357.94 374.90 Td (stock ) Tj ET Q q 0 0 0 rg BT 381.64 374.90 Td (at ) Tj ET Q q 0 0 0 rg BT 391.45 374.90 Td (the ) Tj ET Q q 0 0 0 rg BT 406.25 374.90 Td (end ) Tj ET Q q 0 0 0 rg BT 423.28 374.90 Td (of ) Tj ET Q q 0 0 0 rg BT 434.20 374.90 Td (the ) Tj ET Q q 0 0 0 rg BT 449.01 374.90 Td (specified ) Tj ET Q q 0 0 0 rg BT 487.69 374.90 Td (vesting ) Tj ET Q q 0 0 0 rg BT 519.17 374.90 Td (period ) Tj ET Q q 0 0 0 rg BT 547.30 374.90 Td (but ) Tj ET Q q 0 0 0 rg BT 562.67 374.90 Td (has ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 362.90 Td (no ) Tj ET Q q 0 0 0 rg BT 48.50 362.90 Td (voting ) Tj ET Q q 0 0 0 rg BT 76.56 362.90 Td (rights.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 341.30 Td (Market ) Tj ET Q q 0 0 0 rg BT 67.83 341.30 Td (share ) Tj ET Q q 0 0 0 rg BT 91.89 341.30 Td (units ) Tj ET Q q 0 0 0 rg BT 114.29 341.30 Td (are ) Tj ET Q q 0 0 0 rg BT 129.46 341.30 Td (granted ) Tj ET Q q 0 0 0 rg BT 162.40 341.30 Td (to ) Tj ET Q q 0 0 0 rg BT 173.13 341.30 Td (executives. ) Tj ET Q q 0 0 0 rg BT 220.58 341.30 Td (V) Tj ET Q q 0 0 0 rg BT 226.69 341.30 Td (esting ) Tj ET Q q 0 0 0 rg BT 253.54 341.30 Td (is ) Tj ET Q q 0 0 0 rg BT 263.16 341.30 Td (conditioned ) Tj ET Q q 0 0 0 rg BT 313.33 341.30 Td (upon ) Tj ET Q q 0 0 0 rg BT 336.29 341.30 Td (continuous ) Tj ET Q q 0 0 0 rg BT 383.13 341.30 Td (employment ) Tj ET Q q 0 0 0 rg BT 436.08 341.30 Td (until ) Tj ET Q q 0 0 0 rg BT 457.37 341.30 Td (the ) Tj ET Q q 0 0 0 rg BT 472.54 341.30 Td (vesting ) Tj ET Q q 0 0 0 rg BT 504.38 341.30 Td (date ) Tj ET Q q 0 0 0 rg BT 524.00 341.30 Td (and ) Tj ET Q q 0 0 0 rg BT 541.39 341.30 Td (a ) Tj ET Q q 0 0 0 rg BT 548.79 341.30 Td (payout ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.30 Td (factor ) Tj ET Q q 0 0 0 rg BT 61.71 329.30 Td (of ) Tj ET Q q 0 0 0 rg BT 72.43 329.30 Td (at ) Tj ET Q q 0 0 0 rg BT 82.04 329.30 Td (least ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 102.75 329.30 Td (60%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 121.08 329.30 Td ( ) Tj ET Q q 0 0 0 rg BT 123.48 329.30 Td (of ) Tj ET Q q 0 0 0 rg BT 134.20 329.30 Td (the ) Tj ET Q q 0 0 0 rg BT 148.81 329.30 Td (share ) Tj ET Q q 0 0 0 rg BT 172.30 329.30 Td (price ) Tj ET Q q 0 0 0 rg BT 194.67 329.30 Td (on ) Tj ET Q q 0 0 0 rg BT 207.06 329.30 Td (the ) Tj ET Q q 0 0 0 rg BT 221.67 329.30 Td (award ) Tj ET Q q 0 0 0 rg BT 248.49 329.30 Td (date. ) Tj ET Q q 0 0 0 rg BT 269.87 329.30 Td (The ) Tj ET Q q 0 0 0 rg BT 287.81 329.30 Td (payout ) Tj ET Q q 0 0 0 rg BT 317.41 329.30 Td (factor ) Tj ET Q q 0 0 0 rg BT 343.12 329.30 Td (is ) Tj ET Q q 0 0 0 rg BT 352.18 329.30 Td (the ) Tj ET Q q 0 0 0 rg BT 366.79 329.30 Td (share ) Tj ET Q q 0 0 0 rg BT 390.28 329.30 Td (price ) Tj ET Q q 0 0 0 rg BT 412.66 329.30 Td (on ) Tj ET Q q 0 0 0 rg BT 425.05 329.30 Td (vesting ) Tj ET Q q 0 0 0 rg BT 456.33 329.30 Td (date ) Tj ET Q q 0 0 0 rg BT 475.38 329.30 Td (divided ) Tj ET Q q 0 0 0 rg BT 507.76 329.30 Td (by ) Tj ET Q q 0 0 0 rg BT 520.15 329.30 Td (share ) Tj ET Q q 0 0 0 rg BT 543.64 329.30 Td (price ) Tj ET Q q 0 0 0 rg BT 566.02 329.30 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.30 Td (award ) Tj ET Q q 0 0 0 rg BT 62.99 317.30 Td (date, ) Tj ET Q q 0 0 0 rg BT 84.71 317.30 Td (with ) Tj ET Q q 0 0 0 rg BT 105.05 317.30 Td (a ) Tj ET Q q 0 0 0 rg BT 112.05 317.30 Td (maximum ) Tj ET Q q 0 0 0 rg BT 155.17 317.30 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 166.06 317.30 Td (200%) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 189.39 317.30 Td (. ) Tj ET Q q 0 0 0 rg BT 194.26 317.30 Td (The ) Tj ET Q q 0 0 0 rg BT 212.37 317.30 Td (share ) Tj ET Q q 0 0 0 rg BT 236.04 317.30 Td (price ) Tj ET Q q 0 0 0 rg BT 258.58 317.30 Td (used ) Tj ET Q q 0 0 0 rg BT 279.48 317.30 Td (in ) Tj ET Q q 0 0 0 rg BT 289.82 317.30 Td (the ) Tj ET Q q 0 0 0 rg BT 304.60 317.30 Td (payout ) Tj ET Q q 0 0 0 rg BT 334.38 317.30 Td (factor ) Tj ET Q q 0 0 0 rg BT 360.25 317.30 Td (is ) Tj ET Q q 0 0 0 rg BT 369.49 317.30 Td (calculated ) Tj ET Q q 0 0 0 rg BT 412.58 317.30 Td (using ) Tj ET Q q 0 0 0 rg BT 436.81 317.30 Td (an ) Tj ET Q q 0 0 0 rg BT 448.81 317.30 Td (average ) Tj ET Q q 0 0 0 rg BT 482.46 317.30 Td (of ) Tj ET Q q 0 0 0 rg BT 493.35 317.30 Td (the ) Tj ET Q q 0 0 0 rg BT 508.13 317.30 Td (closing ) Tj ET Q q 0 0 0 rg BT 539.58 317.30 Td (prices ) Tj ET Q q 0 0 0 rg BT 566.02 317.30 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 305.30 Td (the ) Tj ET Q q 0 0 0 rg BT 50.72 305.30 Td (grant ) Tj ET Q q 0 0 0 rg BT 73.76 305.30 Td (or ) Tj ET Q q 0 0 0 rg BT 84.59 305.30 Td (vest ) Tj ET Q q 0 0 0 rg BT 103.20 305.30 Td (date, ) Tj ET Q q 0 0 0 rg BT 124.86 305.30 Td (and ) Tj ET Q q 0 0 0 rg BT 141.80 305.30 Td (the ) Tj ET Q q 0 0 0 rg BT 156.51 305.30 Td (nine ) Tj ET Q q 0 0 0 rg BT 176.23 305.30 Td (trading ) Tj ET Q q 0 0 0 rg BT 207.05 305.30 Td (days ) Tj ET Q q 0 0 0 rg BT 227.88 305.30 Td (immediately ) Tj ET Q q 0 0 0 rg BT 280.37 305.30 Td (preceding ) Tj ET Q q 0 0 0 rg BT 322.29 305.30 Td (the ) Tj ET Q q 0 0 0 rg BT 337.01 305.30 Td (grant ) Tj ET Q q 0 0 0 rg BT 360.06 305.30 Td (or ) Tj ET Q q 0 0 0 rg BT 370.89 305.30 Td (vest ) Tj ET Q q 0 0 0 rg BT 389.50 305.30 Td (date. ) Tj ET Q q 0 0 0 rg BT 410.97 305.30 Td (V) Tj ET Q q 0 0 0 rg BT 417.08 305.30 Td (esting ) Tj ET Q q 0 0 0 rg BT 443.47 305.30 Td (occurs ) Tj ET Q q 0 0 0 rg BT 472.07 305.30 Td (ratably ) Tj ET Q q 0 0 0 rg BT 502.33 305.30 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.60 305.30 Td (four) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 539.26 305.30 Td ( ) Tj ET Q q 0 0 0 rg BT 541.76 305.30 Td (years.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 283.70 Td (Performance ) Tj ET Q q 0 0 0 rg BT 88.79 283.70 Td (share ) Tj ET Q q 0 0 0 rg BT 111.60 283.70 Td (units ) Tj ET Q q 0 0 0 rg BT 132.76 283.70 Td (are ) Tj ET Q q 0 0 0 rg BT 146.67 283.70 Td (granted ) Tj ET Q q 0 0 0 rg BT 178.37 283.70 Td (to ) Tj ET Q q 0 0 0 rg BT 187.86 283.70 Td (executives, ) Tj ET Q q 0 0 0 rg BT 234.27 283.70 Td (have ) Tj ET Q q 0 0 0 rg BT 254.85 283.70 Td (a ) Tj ET Q q 0 0 0 rg BT 261.00 283.70 Td (three ) Tj ET Q q 0 0 0 rg BT 282.69 283.70 Td (year ) Tj ET Q q 0 0 0 rg BT 301.61 283.70 Td (cycle ) Tj ET Q q 0 0 0 rg BT 324.41 283.70 Td (and ) Tj ET Q q 0 0 0 rg BT 340.56 283.70 Td (are ) Tj ET Q q 0 0 0 rg BT 354.48 283.70 Td (granted ) Tj ET Q q 0 0 0 rg BT 386.17 283.70 Td (as ) Tj ET Q q 0 0 0 rg BT 396.21 283.70 Td (a ) Tj ET Q q 0 0 0 rg BT 402.36 283.70 Td (tar) Tj ET Q q 0 0 0 rg BT 412.72 283.70 Td (get ) Tj ET Q q 0 0 0 rg BT 426.65 283.70 Td (number ) Tj ET Q q 0 0 0 rg BT 458.91 283.70 Td (of ) Tj ET Q q 0 0 0 rg BT 468.94 283.70 Td (units ) Tj ET Q q 0 0 0 rg BT 490.10 283.70 Td (subject ) Tj ET Q q 0 0 0 rg BT 520.14 283.70 Td (to ) Tj ET Q q 0 0 0 rg BT 529.62 283.70 Td (adjustment. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 271.70 Td (The ) Tj ET Q q 0 0 0 rg BT 53.67 271.70 Td (number ) Tj ET Q q 0 0 0 rg BT 86.34 271.70 Td (of ) Tj ET Q q 0 0 0 rg BT 96.79 271.70 Td (shares ) Tj ET Q q 0 0 0 rg BT 123.90 271.70 Td (issued ) Tj ET Q q 0 0 0 rg BT 151.02 271.70 Td (when ) Tj ET Q q 0 0 0 rg BT 174.80 271.70 Td (performance ) Tj ET Q q 0 0 0 rg BT 227.45 271.70 Td (share ) Tj ET Q q 0 0 0 rg BT 250.67 271.70 Td (units ) Tj ET Q q 0 0 0 rg BT 272.24 271.70 Td (vest ) Tj ET Q q 0 0 0 rg BT 290.47 271.70 Td (is ) Tj ET Q q 0 0 0 rg BT 299.26 271.70 Td (determined ) Tj ET Q q 0 0 0 rg BT 346.36 271.70 Td (based ) Tj ET Q q 0 0 0 rg BT 371.25 271.70 Td (on ) Tj ET Q q 0 0 0 rg BT 383.37 271.70 Td (the ) Tj ET Q q 0 0 0 rg BT 397.71 271.70 Td (achievement ) Tj ET Q q 0 0 0 rg BT 450.36 271.70 Td (of ) Tj ET Q q 0 0 0 rg BT 460.81 271.70 Td (performance ) Tj ET Q q 0 0 0 rg BT 513.46 271.70 Td (goals ) Tj ET Q q 0 0 0 rg BT 536.69 271.70 Td (and ) Tj ET Q q 0 0 0 rg BT 553.25 271.70 Td (based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 259.70 Td (on ) Tj ET Q q 0 0 0 rg BT 49.36 259.70 Td (the ) Tj ET Q q 0 0 0 rg BT 64.94 259.70 Td (Company's ) Tj ET Q q 0 0 0 rg BT 112.89 259.70 Td (three-year ) Tj ET Q q 0 0 0 rg BT 156.77 259.70 Td (total ) Tj ET Q q 0 0 0 rg BT 177.91 259.70 Td (shareholder ) Tj ET Q q 0 0 0 rg BT 227.92 259.70 Td (return ) Tj ET Q q 0 0 0 rg BT 255.16 259.70 Td (relative ) Tj ET Q q 0 0 0 rg BT 288.50 259.70 Td (to ) Tj ET Q q 0 0 0 rg BT 299.64 259.70 Td (a ) Tj ET Q q 0 0 0 rg BT 307.45 259.70 Td (peer ) Tj ET Q q 0 0 0 rg BT 328.02 259.70 Td (group ) Tj ET Q q 0 0 0 rg BT 354.71 259.70 Td (of ) Tj ET Q q 0 0 0 rg BT 366.40 259.70 Td (companies. ) Tj ET Q q 0 0 0 rg BT 414.79 259.70 Td (V) Tj ET Q q 0 0 0 rg BT 420.90 259.70 Td (esting ) Tj ET Q q 0 0 0 rg BT 448.15 259.70 Td (is ) Tj ET Q q 0 0 0 rg BT 458.18 259.70 Td (conditioned ) Tj ET Q q 0 0 0 rg BT 508.76 259.70 Td (upon ) Tj ET Q q 0 0 0 rg BT 532.12 259.70 Td (continuous ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 247.70 Td (employment ) Tj ET Q q 0 0 0 rg BT 88.49 247.70 Td (and ) Tj ET Q q 0 0 0 rg BT 105.43 247.70 Td (occurs ) Tj ET Q q 0 0 0 rg BT 134.03 247.70 Td (on ) Tj ET Q q 0 0 0 rg BT 146.53 247.70 Td (the ) Tj ET Q q 0 0 0 rg BT 161.24 247.70 Td (third ) Tj ET Q q 0 0 0 rg BT 182.63 247.70 Td (anniversary ) Tj ET Q q 0 0 0 rg BT 231.78 247.70 Td (of ) Tj ET Q q 0 0 0 rg BT 242.61 247.70 Td (the ) Tj ET Q q 0 0 0 rg BT 257.32 247.70 Td (grant ) Tj ET Q q 0 0 0 rg BT 280.37 247.70 Td (date.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 226.10 Td (Stock-based ) Tj ET Q q 0 0 0 rg BT 86.73 226.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 144.13 226.10 Td (expense ) Tj ET Q q 0 0 0 rg BT 178.20 226.10 Td (for ) Tj ET Q q 0 0 0 rg BT 191.72 226.10 Td (awards ) Tj ET Q q 0 0 0 rg BT 221.90 226.10 Td (ultimately ) Tj ET Q q 0 0 0 rg BT 264.30 226.10 Td (expected ) Tj ET Q q 0 0 0 rg BT 301.69 226.10 Td (to ) Tj ET Q q 0 0 0 rg BT 311.33 226.10 Td (vest ) Tj ET Q q 0 0 0 rg BT 329.29 226.10 Td (is ) Tj ET Q q 0 0 0 rg BT 337.82 226.10 Td (recognized ) Tj ET Q q 0 0 0 rg BT 383.54 226.10 Td (over ) Tj ET Q q 0 0 0 rg BT 403.17 226.10 Td (the ) Tj ET Q q 0 0 0 rg BT 417.24 226.10 Td (vesting ) Tj ET Q q 0 0 0 rg BT 447.99 226.10 Td (period. ) Tj ET Q q 0 0 0 rg BT 477.89 226.10 Td (Forfeitures ) Tj ET Q q 0 0 0 rg BT 523.63 226.10 Td (are ) Tj ET Q q 0 0 0 rg BT 537.69 226.10 Td (estimated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 214.10 Td (based ) Tj ET Q q 0 0 0 rg BT 61.86 214.10 Td (on ) Tj ET Q q 0 0 0 rg BT 74.95 214.10 Td (historical ) Tj ET Q q 0 0 0 rg BT 115.25 214.10 Td (experience ) Tj ET Q q 0 0 0 rg BT 161.63 214.10 Td (at ) Tj ET Q q 0 0 0 rg BT 171.94 214.10 Td (the ) Tj ET Q q 0 0 0 rg BT 187.25 214.10 Td (time ) Tj ET Q q 0 0 0 rg BT 208.11 214.10 Td (of ) Tj ET Q q 0 0 0 rg BT 219.53 214.10 Td (grant ) Tj ET Q q 0 0 0 rg BT 243.16 214.10 Td (and ) Tj ET Q q 0 0 0 rg BT 260.69 214.10 Td (revised ) Tj ET Q q 0 0 0 rg BT 292.65 214.10 Td (in ) Tj ET Q q 0 0 0 rg BT 303.52 214.10 Td (subsequent ) Tj ET Q q 0 0 0 rg BT 351.05 214.10 Td (periods ) Tj ET Q q 0 0 0 rg BT 383.57 214.10 Td (if ) Tj ET Q q 0 0 0 rg BT 392.77 214.10 Td (actual ) Tj ET Q q 0 0 0 rg BT 419.73 214.10 Td (forfeitures ) Tj ET Q q 0 0 0 rg BT 464.46 214.10 Td (dif) Tj ET Q q 0 0 0 rg BT 475.39 214.10 Td (fer ) Tj ET Q q 0 0 0 rg BT 489.58 214.10 Td (from ) Tj ET Q q 0 0 0 rg BT 512.11 214.10 Td (those ) Tj ET Q q 0 0 0 rg BT 536.30 214.10 Td (estimates. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 202.10 Td (Other ) Tj ET Q q 0 0 0 rg BT 61.27 202.10 Td (information ) Tj ET Q q 0 0 0 rg BT 110.98 202.10 Td (related ) Tj ET Q q 0 0 0 rg BT 140.68 202.10 Td (to ) Tj ET Q q 0 0 0 rg BT 150.96 202.10 Td (stock-based ) Tj ET Q q 0 0 0 rg BT 200.67 202.10 Td (compensation ) Tj ET Q q 0 0 0 rg BT 258.71 202.10 Td (benefits ) Tj ET Q q 0 0 0 rg BT 292.87 202.10 Td (are ) Tj ET Q q 0 0 0 rg BT 307.57 202.10 Td (as ) Tj ET Q q 0 0 0 rg BT 318.40 202.10 Td (follows:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 165.60 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 165.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 165.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 165.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 165.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 165.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 165.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 139.60 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 139.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 139.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 139.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 139.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 139.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 506.50 139.60 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 113.60 320.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 356.50 113.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 360.50 113.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 429.50 113.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 433.50 113.60 69.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 502.50 113.60 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rg BT 490.45 700.73 Td (A) Tj ET Q q 0 0 0 rg BT 495.63 700.73 Td (wards) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 534.90 724.73 Td (W) Tj ET Q q 0 0 0 rg BT 542.46 724.73 Td (eighted-) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.55 716.73 Td (A) Tj ET Q q 0 0 0 rg BT 543.73 716.73 Td (verage) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.70 708.73 Td (Grant-Date ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 534.65 700.73 Td (Fair) Tj ET Q q 0 0 0 rg BT 549.17 700.73 Td ( ) Tj ET Q q 0 0 0 rg BT 551.02 700.73 Td (V) Tj ET Q q 0 0 0 rg BT 556.06 700.73 Td (alue) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 699.45 Td (Shares in Millions) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 687.07 Td (Balance at January 1, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.15 687.07 Td (6.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 687.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.15 687.07 Td (21.02) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.15 687.07 Td (4.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 336.00 687.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 687.07 Td (56.90) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.15 687.07 Td (1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 687.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 687.07 Td (61.63) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.15 687.07 Td (4.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.00 687.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 687.07 Td (60.97) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 674.07 Td (Granted) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 208.65 674.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.65 674.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.15 674.07 Td (2.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 674.07 Td (54.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.15 674.07 Td (0.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 674.07 Td (60.14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.15 674.07 Td (1.3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 674.07 Td (57.91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 661.07 Td (Released/Exercised) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.80 661.07 Td (\(2.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 218.65 661.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.15 661.07 Td (23.80) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.80 661.12 Td (\(1.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.65 661.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 661.07 Td (53.00) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.80 661.12 Td (\(0.6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.65 661.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 661.07 Td (54.64) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 505.80 661.12 Td (\(1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.65 661.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 661.07 Td (54.46) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 648.07 Td (Adjustments for actual payout) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 208.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 268.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 366.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 464.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 648.07 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 635.07 Td (Forfeited/Canceled) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 202.80 635.07 Td (\(0.1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 218.65 635.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.15 635.07 Td (25.55) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 309.80 635.12 Td (\(0.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 325.65 635.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 635.07 Td (57.26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.80 635.12 Td (\(0.3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.65 635.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 635.07 Td (62.95) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 505.80 635.12 Td (\(0.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 521.65 635.07 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 635.07 Td (62.21) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 622.07 Td (Balance at December 31, 2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.15 622.07 Td (3.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.15 622.07 Td (19.04) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.15 622.07 Td (4.9) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 622.07 Td (56.85) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.15 622.07 Td (1.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 622.07 Td (62.25) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.15 622.07 Td (3.5) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 622.07 Td (62.57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 596.07 Td (V) Tj ET Q q 0 0 0 rg BT 45.11 596.07 Td (ested or expected to vest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 206.15 596.07 Td (3.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 256.15 596.07 Td (19.04) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.15 596.07 Td (4.3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.15 596.07 Td (56.89) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.15 596.07 Td (1.4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 452.15 596.07 Td (62.27) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.15 596.07 Td (3.3) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 596.07 Td (62.82) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 538.50 379.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 415.50 538.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 419.50 538.50 48.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 467.50 538.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 471.50 538.50 47.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 518.50 538.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 522.50 538.50 54.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 419.5 538.5 m 467.5 538.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 471.5 538.5 m 518.5 538.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 522.5 538.5 m 576.5 538.5 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 425.45 555.73 Td (Restricted) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 481.60 555.73 Td (Market) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 526.75 555.73 Td (Performance) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 542.75 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 423.30 542.73 Td (Stock Units) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 474.45 542.73 Td (Shar) Tj ET Q q 0 0 0 rg BT 490.83 542.73 Td (e Units) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 528.95 542.73 Td (Shar) Tj ET Q q 0 0 0 rg BT 545.25 542.73 Td (e Units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 529.07 Td (Unrecognized compensation cost) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.00 529.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 448.65 529.07 Td (197) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.00 529.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.65 529.07 Td (42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 525.00 529.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 529.07 Td (70) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 516.07 Td (Expected weighted-average period in years of compensation cost to be recognized) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.50 516.07 Td (2.7) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 502.50 516.07 Td (2.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 560.50 516.07 Td (1.7) Tj ET Q BT /F1 10.00 Tf ET 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 477.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 477.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 477.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 477.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 477.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 477.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 477.50 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 451.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 451.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 451.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 451.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 451.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 451.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 451.50 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 425.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 425.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 425.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 425.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 425.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 425.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 425.50 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 399.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 399.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 399.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 399.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 399.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 399.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 399.50 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 373.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 373.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 373.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 373.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 373.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 373.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 373.50 71.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 347.50 317.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 353.50 347.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 357.50 347.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 427.50 347.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 431.50 347.50 70.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 501.50 347.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 347.50 71.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 357.5 477.5 m 427.5 477.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 431.5 477.5 m 501.5 477.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 505.5 477.5 m 576.5 477.5 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 481.75 Td (Amounts in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 384.00 481.73 Td (2017) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 458.00 481.73 Td (2016) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.50 481.73 Td (2015) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 468.07 Td (W) Tj ET Q q 0 0 0 rg BT 48.04 468.07 Td (eighted-average grant date fair value \(per share\):) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 455.07 Td (Restricted stock units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 455.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.15 455.07 Td (54.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 455.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 455.07 Td (60.56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 455.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 455.07 Td (61.18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 442.07 Td (Market share units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.15 442.07 Td (60.14) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 442.07 Td (65.26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 442.07 Td (67.03) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 429.07 Td (Performance share units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 401.15 429.07 Td (57.91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.15 429.07 Td (64.87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 429.07 Td (65.07) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 403.07 Td (Fair value of awards that vested:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 390.07 Td (Restricted stock units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 390.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 390.07 Td (91) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 390.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 390.07 Td (81) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 390.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 390.07 Td (77) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 377.07 Td (Market share units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 377.07 Td (33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 377.07 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 377.07 Td (47) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 57.00 364.07 Td (Performance share units) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 364.07 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 487.65 364.07 Td (93) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 364.07 Td (75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 338.07 Td (T) Tj ET Q q 0 0 0 rg BT 44.41 338.07 Td (otal intrinsic value of stock options exercised) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 360.00 338.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.65 338.07 Td (84) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 434.00 338.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 482.65 338.07 Td (158) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 508.00 338.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 338.07 Td (206) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 314.00 Td (The ) Tj ET Q q 0 0 0 rg BT 53.95 314.00 Td (fair ) Tj ET Q q 0 0 0 rg BT 70.23 314.00 Td (value ) Tj ET Q q 0 0 0 rg BT 94.29 314.00 Td (of ) Tj ET Q q 0 0 0 rg BT 105.03 314.00 Td (restricted ) Tj ET Q q 0 0 0 rg BT 144.64 314.00 Td (stock ) Tj ET Q q 0 0 0 rg BT 168.15 314.00 Td (units, ) Tj ET Q q 0 0 0 rg BT 192.50 314.00 Td (market ) Tj ET Q q 0 0 0 rg BT 222.67 314.00 Td (share ) Tj ET Q q 0 0 0 rg BT 246.17 314.00 Td (units ) Tj ET Q q 0 0 0 rg BT 268.03 314.00 Td (and ) Tj ET Q q 0 0 0 rg BT 284.87 314.00 Td (performance ) Tj ET Q q 0 0 0 rg BT 337.80 314.00 Td (share ) Tj ET Q q 0 0 0 rg BT 361.30 314.00 Td (units ) Tj ET Q q 0 0 0 rg BT 383.15 314.00 Td (approximates ) Tj ET Q q 0 0 0 rg BT 439.43 314.00 Td (the ) Tj ET Q q 0 0 0 rg BT 454.05 314.00 Td (closing ) Tj ET Q q 0 0 0 rg BT 485.34 314.00 Td (trading ) Tj ET Q q 0 0 0 rg BT 516.07 314.00 Td (price ) Tj ET Q q 0 0 0 rg BT 538.46 314.00 Td (of ) Tj ET Q q 0 0 0 rg BT 549.20 314.00 Td (BMS's ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 302.00 Td (common ) Tj ET Q q 0 0 0 rg BT 73.20 302.00 Td (stock ) Tj ET Q q 0 0 0 rg BT 96.52 302.00 Td (on ) Tj ET Q q 0 0 0 rg BT 108.72 302.00 Td (the ) Tj ET Q q 0 0 0 rg BT 123.14 302.00 Td (grant ) Tj ET Q q 0 0 0 rg BT 145.90 302.00 Td (date ) Tj ET Q q 0 0 0 rg BT 164.76 302.00 Td (after ) Tj ET Q q 0 0 0 rg BT 185.28 302.00 Td (adjusting ) Tj ET Q q 0 0 0 rg BT 224.15 302.00 Td (for ) Tj ET Q q 0 0 0 rg BT 238.02 302.00 Td (the ) Tj ET Q q 0 0 0 rg BT 252.44 302.00 Td (units ) Tj ET Q q 0 0 0 rg BT 274.09 302.00 Td (not ) Tj ET Q q 0 0 0 rg BT 289.08 302.00 Td (eligible ) Tj ET Q q 0 0 0 rg BT 321.28 302.00 Td (for ) Tj ET Q q 0 0 0 rg BT 335.14 302.00 Td (accrued ) Tj ET Q q 0 0 0 rg BT 368.43 302.00 Td (dividends. ) Tj ET Q q 0 0 0 rg BT 412.02 302.00 Td (In ) Tj ET Q q 0 0 0 rg BT 422.56 302.00 Td (addition, ) Tj ET Q q 0 0 0 rg BT 460.04 302.00 Td (the ) Tj ET Q q 0 0 0 rg BT 474.46 302.00 Td (fair ) Tj ET Q q 0 0 0 rg BT 490.55 302.00 Td (value ) Tj ET Q q 0 0 0 rg BT 514.41 302.00 Td (of ) Tj ET Q q 0 0 0 rg BT 524.94 302.00 Td (market ) Tj ET Q q 0 0 0 rg BT 554.91 302.00 Td (share ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 290.00 Td (units ) Tj ET Q q 0 0 0 rg BT 57.95 290.00 Td (and ) Tj ET Q q 0 0 0 rg BT 74.89 290.00 Td (performance ) Tj ET Q q 0 0 0 rg BT 127.91 290.00 Td (share ) Tj ET Q q 0 0 0 rg BT 151.51 290.00 Td (units ) Tj ET Q q 0 0 0 rg BT 173.46 290.00 Td (considers ) Tj ET Q q 0 0 0 rg BT 213.72 290.00 Td (the ) Tj ET Q q 0 0 0 rg BT 228.44 290.00 Td (probability ) Tj ET Q q 0 0 0 rg BT 274.82 290.00 Td (of ) Tj ET Q q 0 0 0 rg BT 285.65 290.00 Td (satisfying ) Tj ET Q q 0 0 0 rg BT 327.04 290.00 Td (the ) Tj ET Q q 0 0 0 rg BT 341.76 290.00 Td (payout ) Tj ET Q q 0 0 0 rg BT 371.47 290.00 Td (factor ) Tj ET Q q 0 0 0 rg BT 397.29 290.00 Td (and ) Tj ET Q q 0 0 0 rg BT 414.23 290.00 Td (total ) Tj ET Q q 0 0 0 rg BT 434.50 290.00 Td (shareholder ) Tj ET Q q 0 0 0 rg BT 483.65 290.00 Td (return, ) Tj ET Q q 0 0 0 rg BT 512.52 290.00 Td (respectively) Tj ET Q q 0 0 0 rg BT 560.18 290.00 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 269.00 Td (The ) Tj ET Q q 0 0 0 rg BT 54.05 269.00 Td (following ) Tj ET Q q 0 0 0 rg BT 95.43 269.00 Td (table ) Tj ET Q q 0 0 0 rg BT 117.37 269.00 Td (summarizes ) Tj ET Q q 0 0 0 rg BT 167.63 269.00 Td (significant ) Tj ET Q q 0 0 0 rg BT 212.34 269.00 Td (ranges ) Tj ET Q q 0 0 0 rg BT 240.94 269.00 Td (of ) Tj ET Q q 0 0 0 rg BT 251.77 269.00 Td (outstanding ) Tj ET Q q 0 0 0 rg BT 300.94 269.00 Td (and ) Tj ET Q q 0 0 0 rg BT 317.88 269.00 Td (exercisable ) Tj ET Q q 0 0 0 rg BT 365.35 269.00 Td (options ) Tj ET Q q 0 0 0 rg BT 397.29 269.00 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.01 269.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 465.59 269.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 485.59 269.00 Td (:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 217.50 156.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 192.50 217.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 196.50 217.50 108.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 304.50 217.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 308.50 217.50 89.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 397.50 217.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 401.50 217.50 85.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 486.50 217.50 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 490.50 217.50 86.00 -13.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 196.5 246.5 m 304.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 304.5 246.5 m 308.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 308.5 246.5 m 397.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 397.5 246.5 m 401.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 401.5 246.5 m 486.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 486.5 246.5 m 490.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 246.5 m 576.5 246.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 196.5 217.5 m 304.5 217.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 308.5 217.5 m 397.5 217.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 401.5 217.5 m 486.5 217.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 490.5 217.5 m 576.5 217.5 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 250.45 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 321.90 250.58 Td (Options Outstanding and Exer) Tj ET Q q 0 0 0 rg BT 426.90 250.58 Td (cisable) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 39.00 221.73 Td ( Range of Exer) Tj ET Q q 0 0 0 rg BT 89.73 221.73 Td (cise Prices) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 235.85 237.73 Td (Number) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 200.50 229.73 Td (Outstanding and Exer) Tj ET Q q 0 0 0 rg BT 276.38 229.73 Td (cisable ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 229.40 221.73 Td (\(in millions\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 321.00 237.73 Td (W) Tj ET Q q 0 0 0 rg BT 328.56 237.73 Td (eighted-A) Tj ET Q q 0 0 0 rg BT 361.29 237.73 Td (verage) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 312.15 229.73 Td (Remaining Contractual) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 328.50 221.73 Td (Life \(in years\)) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 412.00 237.73 Td (W) Tj ET Q q 0 0 0 rg BT 419.56 237.73 Td (eighted-A) Tj ET Q q 0 0 0 rg BT 452.29 237.73 Td (verage) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 419.25 229.73 Td (Exer) Tj ET Q q 0 0 0 rg BT 435.54 229.73 Td (cise Price ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 426.65 221.73 Td (Per) Tj ET Q q 0 0 0 rg BT 438.49 221.73 Td ( Shar) Tj ET Q q 0 0 0 rg BT 456.80 221.73 Td (e) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 515.50 237.73 Td (Aggr) Tj ET Q q 0 0 0 rg BT 532.68 237.73 Td (egate) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 507.75 229.73 Td (Intrinsic ) Tj ET Q q 0 0 0 rg BT 538.94 229.73 Td (V) Tj ET Q q 0 0 0 rg BT 543.98 229.73 Td (alue ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 512.40 221.73 Td (\(in millions\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 208.07 Td ($17 - $24) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 288.15 208.07 Td (3.8) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 376.50 208.07 Td (0.83) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.00 208.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 460.15 208.07 Td (19.04) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.00 208.07 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 208.07 Td (160) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 184.00 Td (The ) Tj ET Q q 0 0 0 rg BT 53.88 184.00 Td (aggregate ) Tj ET Q q 0 0 0 rg BT 95.08 184.00 Td (intrinsic ) Tj ET Q q 0 0 0 rg BT 130.20 184.00 Td (value ) Tj ET Q q 0 0 0 rg BT 154.19 184.00 Td (in ) Tj ET Q q 0 0 0 rg BT 164.31 184.00 Td (the ) Tj ET Q q 0 0 0 rg BT 178.86 184.00 Td (preceding ) Tj ET Q q 0 0 0 rg BT 220.62 184.00 Td (table ) Tj ET Q q 0 0 0 rg BT 242.39 184.00 Td (represents ) Tj ET Q q 0 0 0 rg BT 285.27 184.00 Td (the ) Tj ET Q q 0 0 0 rg BT 299.82 184.00 Td (total ) Tj ET Q q 0 0 0 rg BT 319.93 184.00 Td (pretax ) Tj ET Q q 0 0 0 rg BT 347.26 184.00 Td (intrinsic ) Tj ET Q q 0 0 0 rg BT 382.37 184.00 Td (value, ) Tj ET Q q 0 0 0 rg BT 408.86 184.00 Td (based ) Tj ET Q q 0 0 0 rg BT 433.97 184.00 Td (on ) Tj ET Q q 0 0 0 rg BT 446.31 184.00 Td (the ) Tj ET Q q 0 0 0 rg BT 460.86 184.00 Td (closing ) Tj ET Q q 0 0 0 rg BT 492.09 184.00 Td (stock ) Tj ET Q q 0 0 0 rg BT 515.53 184.00 Td (price ) Tj ET Q q 0 0 0 rg BT 537.86 184.00 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 548.52 184.00 Td ($61.28) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 172.00 Td (on ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 48.50 172.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 107.08 172.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 127.08 172.00 Td (.) Tj ET Q endstream endobj 197 0 obj <> endobj 198 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (98) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 749.25 Td (18) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 749.25 Td (. LEGAL) Tj ET Q q 0 0 0 rg BT 107.95 749.25 Td ( PROCEEDINGS ) Tj ET Q q 0 0 0 rg BT 185.74 749.25 Td (AND CONTINGENCIES) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 734.25 Td (The ) Tj ET Q q 0 0 0 rg BT 52.91 734.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 93.17 734.25 Td (and ) Tj ET Q q 0 0 0 rg BT 108.97 734.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 137.54 734.25 Td (of ) Tj ET Q q 0 0 0 rg BT 147.24 734.25 Td (its ) Tj ET Q q 0 0 0 rg BT 158.05 734.25 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 206.63 734.25 Td (are ) Tj ET Q q 0 0 0 rg BT 220.21 734.25 Td (involved ) Tj ET Q q 0 0 0 rg BT 256.57 734.25 Td (in ) Tj ET Q q 0 0 0 rg BT 265.71 734.25 Td (various ) Tj ET Q q 0 0 0 rg BT 296.52 734.25 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 333.16 734.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 363.13 734.25 Td (government ) Tj ET Q q 0 0 0 rg BT 412.26 734.25 Td (investigations ) Tj ET Q q 0 0 0 rg BT 469.18 734.25 Td (and ) Tj ET Q q 0 0 0 rg BT 484.98 734.25 Td (other ) Tj ET Q q 0 0 0 rg BT 506.90 734.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 527.70 734.25 Td (proceedings ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 722.25 Td (that ) Tj ET Q q 0 0 0 rg BT 53.69 722.25 Td (arise ) Tj ET Q q 0 0 0 rg BT 75.26 722.25 Td (in ) Tj ET Q q 0 0 0 rg BT 85.73 722.25 Td (the ) Tj ET Q q 0 0 0 rg BT 100.64 722.25 Td (ordinary ) Tj ET Q q 0 0 0 rg BT 137.22 722.25 Td (course ) Tj ET Q q 0 0 0 rg BT 166.01 722.25 Td (of ) Tj ET Q q 0 0 0 rg BT 177.03 722.25 Td (business. ) Tj ET Q q 0 0 0 rg BT 215.92 722.25 Td (These ) Tj ET Q q 0 0 0 rg BT 242.50 722.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 271.29 722.25 Td (or ) Tj ET Q q 0 0 0 rg BT 282.32 722.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 333.33 722.25 Td (can ) Tj ET Q q 0 0 0 rg BT 349.90 722.25 Td (involve ) Tj ET Q q 0 0 0 rg BT 382.59 722.25 Td (various ) Tj ET Q q 0 0 0 rg BT 414.72 722.25 Td (types ) Tj ET Q q 0 0 0 rg BT 438.52 722.25 Td (of ) Tj ET Q q 0 0 0 rg BT 449.55 722.25 Td (parties, ) Tj ET Q q 0 0 0 rg BT 481.40 722.25 Td (including ) Tj ET Q q 0 0 0 rg BT 521.87 722.25 Td (governments, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 710.25 Td (competitors, ) Tj ET Q q 0 0 0 rg BT 87.51 710.25 Td (customers, ) Tj ET Q q 0 0 0 rg BT 132.35 710.25 Td (suppliers, ) Tj ET Q q 0 0 0 rg BT 172.76 710.25 Td (service ) Tj ET Q q 0 0 0 rg BT 202.87 710.25 Td (providers, ) Tj ET Q q 0 0 0 rg BT 244.94 710.25 Td (licensees, ) Tj ET Q q 0 0 0 rg BT 285.33 710.25 Td (employees, ) Tj ET Q q 0 0 0 rg BT 332.39 710.25 Td (or ) Tj ET Q q 0 0 0 rg BT 342.51 710.25 Td (shareholders, ) Tj ET Q q 0 0 0 rg BT 397.35 710.25 Td (among ) Tj ET Q q 0 0 0 rg BT 426.36 710.25 Td (others. ) Tj ET Q q 0 0 0 rg BT 454.97 710.25 Td (The ) Tj ET Q q 0 0 0 rg BT 472.31 710.25 Td (resolution ) Tj ET Q q 0 0 0 rg BT 514.10 710.25 Td (of ) Tj ET Q q 0 0 0 rg BT 524.23 710.25 Td (these ) Tj ET Q q 0 0 0 rg BT 546.57 710.25 Td (matters ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 698.25 Td (often ) Tj ET Q q 0 0 0 rg BT 60.39 698.25 Td (develops ) Tj ET Q q 0 0 0 rg BT 99.78 698.25 Td (over ) Tj ET Q q 0 0 0 rg BT 121.39 698.25 Td (a ) Tj ET Q q 0 0 0 rg BT 129.67 698.25 Td (long ) Tj ET Q q 0 0 0 rg BT 151.30 698.25 Td (period ) Tj ET Q q 0 0 0 rg BT 180.69 698.25 Td (of ) Tj ET Q q 0 0 0 rg BT 192.86 698.25 Td (time ) Tj ET Q q 0 0 0 rg BT 214.48 698.25 Td (and ) Tj ET Q q 0 0 0 rg BT 232.76 698.25 Td (expectations ) Tj ET Q q 0 0 0 rg BT 286.58 698.25 Td (can ) Tj ET Q q 0 0 0 rg BT 304.30 698.25 Td (change ) Tj ET Q q 0 0 0 rg BT 336.46 698.25 Td (as ) Tj ET Q q 0 0 0 rg BT 348.63 698.25 Td (a ) Tj ET Q q 0 0 0 rg BT 356.92 698.25 Td (result ) Tj ET Q q 0 0 0 rg BT 382.98 698.25 Td (of ) Tj ET Q q 0 0 0 rg BT 395.15 698.25 Td (new ) Tj ET Q q 0 0 0 rg BT 415.65 698.25 Td (findings, ) Tj ET Q q 0 0 0 rg BT 454.77 698.25 Td (rulings, ) Tj ET Q q 0 0 0 rg BT 488.90 698.25 Td (appeals ) Tj ET Q q 0 0 0 rg BT 522.72 698.25 Td (or ) Tj ET Q q 0 0 0 rg BT 534.90 698.25 Td (settlement ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 686.25 Td (arrangements. ) Tj ET Q q 0 0 0 rg BT 93.96 686.25 Td (The ) Tj ET Q q 0 0 0 rg BT 111.23 686.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 151.84 686.25 Td (recognizes ) Tj ET Q q 0 0 0 rg BT 196.32 686.25 Td (accruals ) Tj ET Q q 0 0 0 rg BT 230.80 686.25 Td (for ) Tj ET Q q 0 0 0 rg BT 244.18 686.25 Td (such ) Tj ET Q q 0 0 0 rg BT 264.23 686.25 Td (contingencies ) Tj ET Q q 0 0 0 rg BT 320.94 686.25 Td (when ) Tj ET Q q 0 0 0 rg BT 344.32 686.25 Td (it ) Tj ET Q q 0 0 0 rg BT 351.60 686.25 Td (is ) Tj ET Q q 0 0 0 rg BT 360.00 686.25 Td (probable ) Tj ET Q q 0 0 0 rg BT 396.71 686.25 Td (that ) Tj ET Q q 0 0 0 rg BT 413.42 686.25 Td (a ) Tj ET Q q 0 0 0 rg BT 419.59 686.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 452.42 686.25 Td (will ) Tj ET Q q 0 0 0 rg BT 469.70 686.25 Td (be ) Tj ET Q q 0 0 0 rg BT 480.86 686.25 Td (incurred ) Tj ET Q q 0 0 0 rg BT 515.90 686.25 Td (and ) Tj ET Q q 0 0 0 rg BT 532.06 686.25 Td (the ) Tj ET Q q 0 0 0 rg BT 546.00 686.25 Td (amount ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 674.25 Td (of ) Tj ET Q q 0 0 0 rg BT 45.98 674.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 63.20 674.25 Td (can ) Tj ET Q q 0 0 0 rg BT 78.72 674.25 Td (be ) Tj ET Q q 0 0 0 rg BT 89.81 674.25 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 134.78 674.25 Td (estimated. ) Tj ET Q q 0 0 0 rg BT 177.13 674.25 Td (These ) Tj ET Q q 0 0 0 rg BT 202.66 674.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 233.75 674.25 Td (involve ) Tj ET Q q 0 0 0 rg BT 265.40 674.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 291.48 674.25 Td (infringement, ) Tj ET Q q 0 0 0 rg BT 347.28 674.25 Td (antitrust, ) Tj ET Q q 0 0 0 rg BT 384.21 674.25 Td (securities, ) Tj ET Q q 0 0 0 rg BT 426.12 674.25 Td (pricing, ) Tj ET Q q 0 0 0 rg BT 458.60 674.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 479.69 674.25 Td (and ) Tj ET Q q 0 0 0 rg BT 495.78 674.25 Td (marketing ) Tj ET Q q 0 0 0 rg BT 537.98 674.25 Td (practices, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 662.25 Td (environmental, ) Tj ET Q q 0 0 0 rg BT 99.20 662.25 Td (commercial, ) Tj ET Q q 0 0 0 rg BT 151.84 662.25 Td (contractual ) Tj ET Q q 0 0 0 rg BT 199.20 662.25 Td (rights, ) Tj ET Q q 0 0 0 rg BT 227.42 662.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 266.46 662.25 Td (obligations, ) Tj ET Q q 0 0 0 rg BT 316.35 662.25 Td (health ) Tj ET Q q 0 0 0 rg BT 343.72 662.25 Td (and ) Tj ET Q q 0 0 0 rg BT 361.10 662.25 Td (safety ) Tj ET Q q 0 0 0 rg BT 387.92 662.25 Td (matters, ) Tj ET Q q 0 0 0 rg BT 422.79 662.25 Td (consumer ) Tj ET Q q 0 0 0 rg BT 464.61 662.25 Td (fraud, ) Tj ET Q q 0 0 0 rg BT 491.15 662.25 Td (employment ) Tj ET Q q 0 0 0 rg BT 544.08 662.25 Td (matters, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 650.25 Td (product ) Tj ET Q q 0 0 0 rg BT 69.35 650.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 103.27 650.25 Td (and ) Tj ET Q q 0 0 0 rg BT 120.51 650.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 161.63 650.25 Td (coverage. ) Tj ET Q q 0 0 0 rg BT 203.02 650.25 Td (Legal ) Tj ET Q q 0 0 0 rg BT 228.59 650.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 279.71 650.25 Td (that ) Tj ET Q q 0 0 0 rg BT 297.51 650.25 Td (are ) Tj ET Q q 0 0 0 rg BT 312.52 650.25 Td (material ) Tj ET Q q 0 0 0 rg BT 348.08 650.25 Td (or ) Tj ET Q q 0 0 0 rg BT 359.22 650.25 Td (that ) Tj ET Q q 0 0 0 rg BT 377.02 650.25 Td (the ) Tj ET Q q 0 0 0 rg BT 392.04 650.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 433.73 650.25 Td (believes ) Tj ET Q q 0 0 0 rg BT 469.30 650.25 Td (could ) Tj ET Q q 0 0 0 rg BT 494.33 650.25 Td (become ) Tj ET Q q 0 0 0 rg BT 528.22 650.25 Td (material ) Tj ET Q q 0 0 0 rg BT 563.79 650.25 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 638.25 Td (described ) Tj ET Q q 0 0 0 rg BT 76.82 638.25 Td (below) Tj ET Q q 0 0 0 rg BT 100.60 638.25 Td (.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 620.25 Td (Although ) Tj ET Q q 0 0 0 rg BT 76.27 620.25 Td (the ) Tj ET Q q 0 0 0 rg BT 90.99 620.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 132.37 620.25 Td (believes ) Tj ET Q q 0 0 0 rg BT 167.63 620.25 Td (it ) Tj ET Q q 0 0 0 rg BT 175.68 620.25 Td (has ) Tj ET Q q 0 0 0 rg BT 191.50 620.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 236.77 620.25 Td (defenses ) Tj ET Q q 0 0 0 rg BT 273.70 620.25 Td (in ) Tj ET Q q 0 0 0 rg BT 283.97 620.25 Td (these ) Tj ET Q q 0 0 0 rg BT 307.01 620.25 Td (matters, ) Tj ET Q q 0 0 0 rg BT 341.44 620.25 Td (there ) Tj ET Q q 0 0 0 rg BT 363.92 620.25 Td (can ) Tj ET Q q 0 0 0 rg BT 380.29 620.25 Td (be ) Tj ET Q q 0 0 0 rg BT 392.23 620.25 Td (no ) Tj ET Q q 0 0 0 rg BT 404.72 620.25 Td (assurance ) Tj ET Q q 0 0 0 rg BT 446.08 620.25 Td (that ) Tj ET Q q 0 0 0 rg BT 463.57 620.25 Td (there ) Tj ET Q q 0 0 0 rg BT 486.05 620.25 Td (will ) Tj ET Q q 0 0 0 rg BT 504.11 620.25 Td (not ) Tj ET Q q 0 0 0 rg BT 519.38 620.25 Td (be ) Tj ET Q q 0 0 0 rg BT 531.31 620.25 Td (an ) Tj ET Q q 0 0 0 rg BT 543.25 620.25 Td (increase ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 608.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.98 608.25 Td (the ) Tj ET Q q 0 0 0 rg BT 62.40 608.25 Td (scope ) Tj ET Q q 0 0 0 rg BT 88.37 608.25 Td (of ) Tj ET Q q 0 0 0 rg BT 99.90 608.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 135.31 608.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 167.95 608.25 Td (or ) Tj ET Q q 0 0 0 rg BT 179.48 608.25 Td (that ) Tj ET Q q 0 0 0 rg BT 197.67 608.25 Td (any ) Tj ET Q q 0 0 0 rg BT 215.31 608.25 Td (future ) Tj ET Q q 0 0 0 rg BT 242.39 608.25 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 280.87 608.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 312.67 608.25 Td (government ) Tj ET Q q 0 0 0 rg BT 363.64 608.25 Td (investigations ) Tj ET Q q 0 0 0 rg BT 422.39 608.25 Td (or ) Tj ET Q q 0 0 0 rg BT 433.92 608.25 Td (other ) Tj ET Q q 0 0 0 rg BT 457.67 608.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 480.30 608.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 531.82 608.25 Td (will ) Tj ET Q q 0 0 0 rg BT 550.58 608.25 Td (not ) Tj ET Q q 0 0 0 rg BT 566.56 608.25 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 596.25 Td (material. ) Tj ET Q q 0 0 0 rg BT 74.14 596.25 Td (Unless ) Tj ET Q q 0 0 0 rg BT 104.25 596.25 Td (otherwise ) Tj ET Q q 0 0 0 rg BT 146.01 596.25 Td (noted, ) Tj ET Q q 0 0 0 rg BT 173.61 596.25 Td (the ) Tj ET Q q 0 0 0 rg BT 188.71 596.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 230.49 596.25 Td (is ) Tj ET Q q 0 0 0 rg BT 240.04 596.25 Td (unable ) Tj ET Q q 0 0 0 rg BT 269.58 596.25 Td (to ) Tj ET Q q 0 0 0 rg BT 280.24 596.25 Td (assess ) Tj ET Q q 0 0 0 rg BT 307.57 596.25 Td (the ) Tj ET Q q 0 0 0 rg BT 322.67 596.25 Td (outcome ) Tj ET Q q 0 0 0 rg BT 359.99 596.25 Td (of ) Tj ET Q q 0 0 0 rg BT 371.21 596.25 Td (the ) Tj ET Q q 0 0 0 rg BT 386.31 596.25 Td (respective ) Tj ET Q q 0 0 0 rg BT 429.73 596.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 468.72 596.25 Td (nor ) Tj ET Q q 0 0 0 rg BT 484.93 596.25 Td (is ) Tj ET Q q 0 0 0 rg BT 494.49 596.25 Td (it ) Tj ET Q q 0 0 0 rg BT 502.93 596.25 Td (able ) Tj ET Q q 0 0 0 rg BT 522.47 596.25 Td (to ) Tj ET Q q 0 0 0 rg BT 533.13 596.25 Td (provide ) Tj ET Q q 0 0 0 rg BT 566.56 596.25 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 584.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 77.60 584.25 Td (range ) Tj ET Q q 0 0 0 rg BT 103.09 584.25 Td (of ) Tj ET Q q 0 0 0 rg BT 114.71 584.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 152.98 584.25 Td (loss. ) Tj ET Q q 0 0 0 rg BT 174.33 584.25 Td (Furthermore, ) Tj ET Q q 0 0 0 rg BT 230.10 584.25 Td (failure ) Tj ET Q q 0 0 0 rg BT 259.47 584.25 Td (to ) Tj ET Q q 0 0 0 rg BT 270.54 584.25 Td (enforce ) Tj ET Q q 0 0 0 rg BT 303.80 584.25 Td (our ) Tj ET Q q 0 0 0 rg BT 320.41 584.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 348.13 584.25 Td (rights ) Tj ET Q q 0 0 0 rg BT 374.19 584.25 Td (would ) Tj ET Q q 0 0 0 rg BT 402.47 584.25 Td (likely ) Tj ET Q q 0 0 0 rg BT 428.53 584.25 Td (result ) Tj ET Q q 0 0 0 rg BT 454.03 584.25 Td (in ) Tj ET Q q 0 0 0 rg BT 465.09 584.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 511.15 584.25 Td (decreases ) Tj ET Q q 0 0 0 rg BT 552.74 584.25 Td (in ) Tj ET Q q 0 0 0 rg BT 563.80 584.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 572.25 Td (respective ) Tj ET Q q 0 0 0 rg BT 79.03 572.25 Td (product ) Tj ET Q q 0 0 0 rg BT 112.08 572.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 150.12 572.25 Td (from ) Tj ET Q q 0 0 0 rg BT 172.05 572.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 203.98 572.25 Td (competition.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 551.25 Td (INTELLECTUAL) Tj ET Q q 0 0 0 rg BT 114.92 551.25 Td ( PROPER) Tj ET Q q 0 0 0 rg BT 158.17 551.25 Td (TY) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 535.25 Td (Plavix* ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 69.60 535.25 Td (- ) Tj ET Q q 0 0 0 rg BT 74.88 535.25 Td (Australia) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 519.25 Td (As ) Tj ET Q q 0 0 0 rg BT 49.42 519.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 93.94 519.25 Td (disclosed, ) Tj ET Q q 0 0 0 rg BT 135.97 519.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 164.38 519.25 Td (was ) Tj ET Q q 0 0 0 rg BT 182.24 519.25 Td (notified ) Tj ET Q q 0 0 0 rg BT 215.65 519.25 Td (that, ) Tj ET Q q 0 0 0 rg BT 235.46 519.25 Td (in ) Tj ET Q q 0 0 0 rg BT 245.03 519.25 Td (August ) Tj ET Q q 0 0 0 rg BT 276.23 519.25 Td (2007, ) Tj ET Q q 0 0 0 rg BT 301.04 519.25 Td (GenRx ) Tj ET Q q 0 0 0 rg BT 331.67 519.25 Td (Proprietary ) Tj ET Q q 0 0 0 rg BT 378.97 519.25 Td (Limited ) Tj ET Q q 0 0 0 rg BT 412.93 519.25 Td (\(GenRx\) ) Tj ET Q q 0 0 0 rg BT 450.23 519.25 Td (obtained ) Tj ET Q q 0 0 0 rg BT 486.97 519.25 Td (regulatory ) Tj ET Q q 0 0 0 rg BT 530.37 519.25 Td (approval ) Tj ET Q q 0 0 0 rg BT 567.67 519.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 507.25 Td (an ) Tj ET Q q 0 0 0 rg BT 46.97 507.25 Td (application ) Tj ET Q q 0 0 0 rg BT 92.94 507.25 Td (for ) Tj ET Q q 0 0 0 rg BT 106.13 507.25 Td (clopidogrel ) Tj ET Q q 0 0 0 rg BT 153.21 507.25 Td (bisulfate ) Tj ET Q q 0 0 0 rg BT 189.18 507.25 Td (75mg ) Tj ET Q q 0 0 0 rg BT 213.50 507.25 Td (tablets ) Tj ET Q q 0 0 0 rg BT 241.13 507.25 Td (in ) Tj ET Q q 0 0 0 rg BT 250.11 507.25 Td (Australia. ) Tj ET Q q 0 0 0 rg BT 290.80 507.25 Td (GenRx, ) Tj ET Q q 0 0 0 rg BT 323.17 507.25 Td (formerly ) Tj ET Q q 0 0 0 rg BT 359.69 507.25 Td (a ) Tj ET Q q 0 0 0 rg BT 365.66 507.25 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 408.31 507.25 Td (of ) Tj ET Q q 0 0 0 rg BT 417.83 507.25 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 448.81 507.25 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 465.61 507.25 Td (\(Apotex\), ) Tj ET Q q 0 0 0 rg BT 505.74 507.25 Td (has ) Tj ET Q q 0 0 0 rg BT 520.61 507.25 Td (since ) Tj ET Q q 0 0 0 rg BT 542.69 507.25 Td (changed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 495.25 Td (its ) Tj ET Q q 0 0 0 rg BT 47.72 495.25 Td (name ) Tj ET Q q 0 0 0 rg BT 71.65 495.25 Td (to ) Tj ET Q q 0 0 0 rg BT 81.20 495.25 Td (Apotex. ) Tj ET Q q 0 0 0 rg BT 115.41 495.25 Td (In ) Tj ET Q q 0 0 0 rg BT 125.51 495.25 Td (August ) Tj ET Q q 0 0 0 rg BT 156.67 495.25 Td (2007, ) Tj ET Q q 0 0 0 rg BT 180.94 495.25 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 212.65 495.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 233.25 495.25 Td (an ) Tj ET Q q 0 0 0 rg BT 244.96 495.25 Td (application ) Tj ET Q q 0 0 0 rg BT 291.66 495.25 Td (in ) Tj ET Q q 0 0 0 rg BT 301.71 495.25 Td (the ) Tj ET Q q 0 0 0 rg BT 316.20 495.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 348.46 495.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 373.51 495.25 Td (of ) Tj ET Q q 0 0 0 rg BT 383.61 495.25 Td (Australia ) Tj ET Q q 0 0 0 rg BT 422.53 495.25 Td (\(the ) Tj ET Q q 0 0 0 rg BT 440.35 495.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 472.61 495.25 Td (Court\) ) Tj ET Q q 0 0 0 rg BT 500.99 495.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 533.81 495.25 Td (revocation ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 483.25 Td (of ) Tj ET Q q 0 0 0 rg BT 47.83 483.25 Td (Sanofi’) Tj ET Q q 0 0 0 rg BT 76.72 483.25 Td (s ) Tj ET Q q 0 0 0 rg BT 83.34 483.25 Td (Australian ) Tj ET Q q 0 0 0 rg BT 128.50 483.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 157.00 483.25 Td (No. 597784 ) Tj ET Q q 0 0 0 rg BT 207.73 483.25 Td (\(Case ) Tj ET Q q 0 0 0 rg BT 234.00 483.25 Td (No. ) Tj ET Q q 0 0 0 rg BT 252.23 483.25 Td (NSD ) Tj ET Q q 0 0 0 rg BT 275.74 483.25 Td (1639 ) Tj ET Q q 0 0 0 rg BT 299.25 483.25 Td (of ) Tj ET Q q 0 0 0 rg BT 311.08 483.25 Td (2007\). ) Tj ET Q q 0 0 0 rg BT 340.42 483.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 370.03 483.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 391.86 483.25 Td (counterclaims ) Tj ET Q q 0 0 0 rg BT 451.45 483.25 Td (of ) Tj ET Q q 0 0 0 rg BT 463.29 483.25 Td (infringement ) Tj ET Q q 0 0 0 rg BT 518.44 483.25 Td (and ) Tj ET Q q 0 0 0 rg BT 536.39 483.25 Td (sought ) Tj ET Q q 0 0 0 rg BT 566.56 483.25 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 471.25 Td (injunction. ) Tj ET Q q 0 0 0 rg BT 81.13 471.25 Td (On ) Tj ET Q q 0 0 0 rg BT 95.42 471.25 Td (September 21, ) Tj ET Q q 0 0 0 rg BT 155.26 471.25 Td (2007, ) Tj ET Q q 0 0 0 rg BT 179.84 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 194.13 471.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 226.19 471.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 251.04 471.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 283.10 471.25 Td (Sanofi’) Tj ET Q q 0 0 0 rg BT 311.99 471.25 Td (s ) Tj ET Q q 0 0 0 rg BT 317.96 471.25 Td (injunction. ) Tj ET Q q 0 0 0 rg BT 362.63 471.25 Td (A) Tj ET Q q 0 0 0 rg BT 369.30 471.25 Td ( ) Tj ET Q q 0 0 0 rg BT 371.37 471.25 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 414.56 471.25 Td (of ) Tj ET Q q 0 0 0 rg BT 424.96 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 439.25 471.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 480.21 471.25 Td (was ) Tj ET Q q 0 0 0 rg BT 497.84 471.25 Td (subsequently ) Tj ET Q q 0 0 0 rg BT 552.13 471.25 Td (added ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 459.25 Td (as ) Tj ET Q q 0 0 0 rg BT 46.83 459.25 Td (a ) Tj ET Q q 0 0 0 rg BT 53.77 459.25 Td (party ) Tj ET Q q 0 0 0 rg BT 76.82 459.25 Td (to ) Tj ET Q q 0 0 0 rg BT 87.10 459.25 Td (the ) Tj ET Q q 0 0 0 rg BT 101.82 459.25 Td (proceedings. ) Tj ET Q q 0 0 0 rg BT 155.14 459.25 Td (In ) Tj ET Q q 0 0 0 rg BT 165.97 459.25 Td (February ) Tj ET Q q 0 0 0 rg BT 204.57 459.25 Td (2008, ) Tj ET Q q 0 0 0 rg BT 229.58 459.25 Td (a ) Tj ET Q q 0 0 0 rg BT 236.52 459.25 Td (second ) Tj ET Q q 0 0 0 rg BT 266.79 459.25 Td (company) Tj ET Q q 0 0 0 rg BT 302.79 459.25 Td (, ) Tj ET Q q 0 0 0 rg BT 307.80 459.25 Td (Spirit ) Tj ET Q q 0 0 0 rg BT 332.53 459.25 Td (Pharmaceuticals ) Tj ET Q q 0 0 0 rg BT 400.56 459.25 Td (Pty) Tj ET Q q 0 0 0 rg BT 413.25 459.25 Td (. ) Tj ET Q q 0 0 0 rg BT 418.25 459.25 Td (Ltd., ) Tj ET Q q 0 0 0 rg BT 439.64 459.25 Td (also ) Tj ET Q q 0 0 0 rg BT 458.25 459.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 479.08 459.25 Td (a ) Tj ET Q q 0 0 0 rg BT 486.02 459.25 Td (revocation ) Tj ET Q q 0 0 0 rg BT 530.72 459.25 Td (suit ) Tj ET Q q 0 0 0 rg BT 547.67 459.25 Td (against ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 447.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.94 447.25 Td (same ) Tj ET Q q 0 0 0 rg BT 74.21 447.25 Td (patent. ) Tj ET Q q 0 0 0 rg BT 103.67 447.25 Td (This ) Tj ET Q q 0 0 0 rg BT 124.18 447.25 Td (case ) Tj ET Q q 0 0 0 rg BT 144.11 447.25 Td (was ) Tj ET Q q 0 0 0 rg BT 162.39 447.25 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 215.65 447.25 Td (with ) Tj ET Q q 0 0 0 rg BT 236.15 447.25 Td (the ) Tj ET Q q 0 0 0 rg BT 250.49 447.25 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 282.66 447.25 Td (case, ) Tj ET Q q 0 0 0 rg BT 305.09 447.25 Td (and ) Tj ET Q q 0 0 0 rg BT 322.25 447.25 Td (a ) Tj ET Q q 0 0 0 rg BT 329.42 447.25 Td (trial ) Tj ET Q q 0 0 0 rg BT 348.24 447.25 Td (occurred ) Tj ET Q q 0 0 0 rg BT 385.94 447.25 Td (in ) Tj ET Q q 0 0 0 rg BT 395.85 447.25 Td (April ) Tj ET Q q 0 0 0 rg BT 419.68 447.25 Td (2008. ) Tj ET Q q 0 0 0 rg BT 444.90 447.25 Td (On ) Tj ET Q q 0 0 0 rg BT 459.25 447.25 Td (August 12, ) Tj ET Q q 0 0 0 rg BT 505.86 447.25 Td (2008, ) Tj ET Q q 0 0 0 rg BT 531.09 447.25 Td (the ) Tj ET Q q 0 0 0 rg BT 546.03 447.25 Td (Federal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 435.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 61.10 435.25 Td (of ) Tj ET Q q 0 0 0 rg BT 71.24 435.25 Td (Australia ) Tj ET Q q 0 0 0 rg BT 110.22 435.25 Td (held ) Tj ET Q q 0 0 0 rg BT 129.76 435.25 Td (that ) Tj ET Q q 0 0 0 rg BT 147.07 435.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 175.50 435.25 Td (of ) Tj ET Q q 0 0 0 rg BT 186.15 435.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 213.47 435.25 Td (No. 597784 ) Tj ET Q q 0 0 0 rg BT 263.01 435.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 300.32 435.25 Td (clopidogrel ) Tj ET Q q 0 0 0 rg BT 348.18 435.25 Td (bisulfate, ) Tj ET Q q 0 0 0 rg BT 387.44 435.25 Td (hydrochloride, ) Tj ET Q q 0 0 0 rg BT 448.35 435.25 Td (hydrobromide, ) Tj ET Q q 0 0 0 rg BT 509.83 435.25 Td (and ) Tj ET Q q 0 0 0 rg BT 526.59 435.25 Td (taurocholate ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 423.25 Td (salts ) Tj ET Q q 0 0 0 rg BT 55.45 423.25 Td (were ) Tj ET Q q 0 0 0 rg BT 76.54 423.25 Td (valid. ) Tj ET Q q 0 0 0 rg BT 100.58 423.25 Td (The ) Tj ET Q q 0 0 0 rg BT 117.80 423.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 149.45 423.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 173.90 423.25 Td (also ) Tj ET Q q 0 0 0 rg BT 191.67 423.25 Td (held ) Tj ET Q q 0 0 0 rg BT 210.56 423.25 Td (that ) Tj ET Q q 0 0 0 rg BT 227.22 423.25 Td (the ) Tj ET Q q 0 0 0 rg BT 241.10 423.25 Td (process ) Tj ET Q q 0 0 0 rg BT 272.76 423.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 303.03 423.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 365.77 423.25 Td (composition ) Tj ET Q q 0 0 0 rg BT 416.89 423.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 447.16 423.25 Td (and ) Tj ET Q q 0 0 0 rg BT 463.26 423.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 487.14 423.25 Td (directed ) Tj ET Q q 0 0 0 rg BT 521.01 423.25 Td (to ) Tj ET Q q 0 0 0 rg BT 530.46 423.25 Td (clopidogrel ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 411.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.93 411.25 Td (its ) Tj ET Q q 0 0 0 rg BT 64.87 411.25 Td (pharmaceutically ) Tj ET Q q 0 0 0 rg BT 136.21 411.25 Td (acceptable ) Tj ET Q q 0 0 0 rg BT 180.89 411.25 Td (salts ) Tj ET Q q 0 0 0 rg BT 201.16 411.25 Td (were ) Tj ET Q q 0 0 0 rg BT 223.08 411.25 Td (invalid. ) Tj ET Q q 0 0 0 rg BT 255.66 411.25 Td (The ) Tj ET Q q 0 0 0 rg BT 273.70 411.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 315.07 411.25 Td (and ) Tj ET Q q 0 0 0 rg BT 332.00 411.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 360.60 411.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 381.42 411.25 Td (notices ) Tj ET Q q 0 0 0 rg BT 412.23 411.25 Td (of ) Tj ET Q q 0 0 0 rg BT 423.05 411.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 451.64 411.25 Td (in ) Tj ET Q q 0 0 0 rg BT 461.90 411.25 Td (the ) Tj ET Q q 0 0 0 rg BT 476.61 411.25 Td (Full ) Tj ET Q q 0 0 0 rg BT 495.22 411.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 520.49 411.25 Td (of ) Tj ET Q q 0 0 0 rg BT 531.31 411.25 Td (the ) Tj ET Q q 0 0 0 rg BT 546.02 411.25 Td (Federal ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 399.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 61.04 399.25 Td (of ) Tj ET Q q 0 0 0 rg BT 71.13 399.25 Td (Australia ) Tj ET Q q 0 0 0 rg BT 110.04 399.25 Td (\(Full ) Tj ET Q q 0 0 0 rg BT 131.75 399.25 Td (Court\) ) Tj ET Q q 0 0 0 rg BT 160.12 399.25 Td (appealing ) Tj ET Q q 0 0 0 rg BT 201.25 399.25 Td (the ) Tj ET Q q 0 0 0 rg BT 215.73 399.25 Td (holding ) Tj ET Q q 0 0 0 rg BT 248.54 399.25 Td (of ) Tj ET Q q 0 0 0 rg BT 259.13 399.25 Td (invalidity ) Tj ET Q q 0 0 0 rg BT 299.72 399.25 Td (of ) Tj ET Q q 0 0 0 rg BT 310.31 399.25 Td (the ) Tj ET Q q 0 0 0 rg BT 324.79 399.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 349.26 399.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 386.51 399.25 Td (clopidogrel ) Tj ET Q q 0 0 0 rg BT 434.31 399.25 Td (and ) Tj ET Q q 0 0 0 rg BT 451.01 399.25 Td (its ) Tj ET Q q 0 0 0 rg BT 462.72 399.25 Td (pharmaceutically ) Tj ET Q q 0 0 0 rg BT 533.83 399.25 Td (acceptable ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 387.25 Td (salts, ) Tj ET Q q 0 0 0 rg BT 59.55 387.25 Td (process ) Tj ET Q q 0 0 0 rg BT 92.82 387.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 124.69 387.25 Td (and ) Tj ET Q q 0 0 0 rg BT 142.41 387.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 206.75 387.25 Td (composition ) Tj ET Q q 0 0 0 rg BT 259.47 387.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 288.85 387.25 Td (which ) Tj ET Q q 0 0 0 rg BT 316.56 387.25 Td (have ) Tj ET Q q 0 0 0 rg BT 338.71 387.25 Td (stayed ) Tj ET Q q 0 0 0 rg BT 367.53 387.25 Td (the ) Tj ET Q q 0 0 0 rg BT 383.02 387.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 416.28 387.25 Td (Court’) Tj ET Q q 0 0 0 rg BT 441.84 387.25 Td (s ) Tj ET Q q 0 0 0 rg BT 449.01 387.25 Td (ruling. ) Tj ET Q q 0 0 0 rg BT 477.94 387.25 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 510.66 387.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 532.25 387.25 Td (a ) Tj ET Q q 0 0 0 rg BT 539.97 387.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 567.67 387.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 375.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 64.85 375.25 Td (appealing ) Tj ET Q q 0 0 0 rg BT 106.48 375.25 Td (the ) Tj ET Q q 0 0 0 rg BT 121.45 375.25 Td (holding ) Tj ET Q q 0 0 0 rg BT 154.76 375.25 Td (of ) Tj ET Q q 0 0 0 rg BT 165.85 375.25 Td (validity ) Tj ET Q q 0 0 0 rg BT 199.16 375.25 Td (of ) Tj ET Q q 0 0 0 rg BT 210.25 375.25 Td (the ) Tj ET Q q 0 0 0 rg BT 225.22 375.25 Td (clopidogrel ) Tj ET Q q 0 0 0 rg BT 273.52 375.25 Td (bisulfate, ) Tj ET Q q 0 0 0 rg BT 313.21 375.25 Td (hydrochloride, ) Tj ET Q q 0 0 0 rg BT 374.56 375.25 Td (hydrobromide, ) Tj ET Q q 0 0 0 rg BT 436.47 375.25 Td (and ) Tj ET Q q 0 0 0 rg BT 453.66 375.25 Td (taurocholate ) Tj ET Q q 0 0 0 rg BT 505.84 375.25 Td (claims. ) Tj ET Q q 0 0 0 rg BT 536.59 375.25 Td (A) Tj ET Q q 0 0 0 rg BT 543.26 375.25 Td ( ) Tj ET Q q 0 0 0 rg BT 546.02 375.25 Td (hearing ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 363.25 Td (on ) Tj ET Q q 0 0 0 rg BT 48.27 363.25 Td (the ) Tj ET Q q 0 0 0 rg BT 62.75 363.25 Td (appeals ) Tj ET Q q 0 0 0 rg BT 95.00 363.25 Td (occurred ) Tj ET Q q 0 0 0 rg BT 132.24 363.25 Td (in ) Tj ET Q q 0 0 0 rg BT 142.28 363.25 Td (February ) Tj ET Q q 0 0 0 rg BT 180.65 363.25 Td (2009. ) Tj ET Q q 0 0 0 rg BT 205.41 363.25 Td (On ) Tj ET Q q 0 0 0 rg BT 219.90 363.25 Td (September 29, ) Tj ET Q q 0 0 0 rg BT 279.93 363.25 Td (2009, ) Tj ET Q q 0 0 0 rg BT 304.70 363.25 Td (the ) Tj ET Q q 0 0 0 rg BT 319.18 363.25 Td (Full ) Tj ET Q q 0 0 0 rg BT 337.56 363.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 362.61 363.25 Td (held ) Tj ET Q q 0 0 0 rg BT 382.09 363.25 Td (all ) Tj ET Q q 0 0 0 rg BT 394.35 363.25 Td (of ) Tj ET Q q 0 0 0 rg BT 404.95 363.25 Td (the ) Tj ET Q q 0 0 0 rg BT 419.43 363.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 447.80 363.25 Td (of ) Tj ET Q q 0 0 0 rg BT 458.39 363.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 485.65 363.25 Td (No. 597784 ) Tj ET Q q 0 0 0 rg BT 535.14 363.25 Td (invalid. ) Tj ET Q q 0 0 0 rg BT 567.68 363.25 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 351.25 Td (November ) Tj ET Q q 0 0 0 rg BT 80.74 351.25 Td (2009, ) Tj ET Q q 0 0 0 rg BT 105.77 351.25 Td (the ) Tj ET Q q 0 0 0 rg BT 120.52 351.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 161.94 351.25 Td (and ) Tj ET Q q 0 0 0 rg BT 178.92 351.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 207.56 351.25 Td (applied ) Tj ET Q q 0 0 0 rg BT 239.52 351.25 Td (to ) Tj ET Q q 0 0 0 rg BT 249.83 351.25 Td (the ) Tj ET Q q 0 0 0 rg BT 264.58 351.25 Td (High ) Tj ET Q q 0 0 0 rg BT 287.12 351.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 312.43 351.25 Td (of ) Tj ET Q q 0 0 0 rg BT 322.73 351.25 Td (Australia ) Tj ET Q q 0 0 0 rg BT 361.92 351.25 Td (\(High ) Tj ET Q q 0 0 0 rg BT 387.79 351.25 Td (Court\) ) Tj ET Q q 0 0 0 rg BT 416.43 351.25 Td (for ) Tj ET Q q 0 0 0 rg BT 430.62 351.25 Td (special ) Tj ET Q q 0 0 0 rg BT 460.92 351.25 Td (leave ) Tj ET Q q 0 0 0 rg BT 484.54 351.25 Td (to ) Tj ET Q q 0 0 0 rg BT 494.86 351.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 523.48 351.25 Td (the ) Tj ET Q q 0 0 0 rg BT 538.23 351.25 Td (judgment ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 339.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.57 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 61.02 339.25 Td (Full ) Tj ET Q q 0 0 0 rg BT 79.38 339.25 Td (Court. ) Tj ET Q q 0 0 0 rg BT 106.90 339.25 Td (In ) Tj ET Q q 0 0 0 rg BT 117.47 339.25 Td (March ) Tj ET Q q 0 0 0 rg BT 145.80 339.25 Td (2010, ) Tj ET Q q 0 0 0 rg BT 170.54 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 185.00 339.25 Td (High ) Tj ET Q q 0 0 0 rg BT 207.24 339.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 232.25 339.25 Td (denied ) Tj ET Q q 0 0 0 rg BT 261.15 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 275.60 339.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 316.73 339.25 Td (and ) Tj ET Q q 0 0 0 rg BT 333.41 339.25 Td (Sanofi’) Tj ET Q q 0 0 0 rg BT 362.29 339.25 Td (s ) Tj ET Q q 0 0 0 rg BT 368.42 339.25 Td (request ) Tj ET Q q 0 0 0 rg BT 399.54 339.25 Td (to ) Tj ET Q q 0 0 0 rg BT 409.56 339.25 Td (hear ) Tj ET Q q 0 0 0 rg BT 429.00 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 443.46 339.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 471.79 339.25 Td (of ) Tj ET Q q 0 0 0 rg BT 482.36 339.25 Td (the ) Tj ET Q q 0 0 0 rg BT 496.82 339.25 Td (Full ) Tj ET Q q 0 0 0 rg BT 515.17 339.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 540.19 339.25 Td (decision. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 327.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.39 327.25 Td (case ) Tj ET Q q 0 0 0 rg BT 74.45 327.25 Td (was ) Tj ET Q q 0 0 0 rg BT 92.84 327.25 Td (remanded ) Tj ET Q q 0 0 0 rg BT 135.11 327.25 Td (to ) Tj ET Q q 0 0 0 rg BT 145.74 327.25 Td (the ) Tj ET Q q 0 0 0 rg BT 160.80 327.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 193.63 327.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 219.25 327.25 Td (for ) Tj ET Q q 0 0 0 rg BT 233.76 327.25 Td (further ) Tj ET Q q 0 0 0 rg BT 263.81 327.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 314.97 327.25 Td (related ) Tj ET Q q 0 0 0 rg BT 345.02 327.25 Td (to ) Tj ET Q q 0 0 0 rg BT 355.65 327.25 Td (damages ) Tj ET Q q 0 0 0 rg BT 393.48 327.25 Td (sought ) Tj ET Q q 0 0 0 rg BT 422.99 327.25 Td (by ) Tj ET Q q 0 0 0 rg BT 435.21 327.25 Td (Apotex. ) Tj ET Q q 0 0 0 rg BT 469.79 327.25 Td (The ) Tj ET Q q 0 0 0 rg BT 488.18 327.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 529.91 327.25 Td (and ) Tj ET Q q 0 0 0 rg BT 546.57 327.25 Td (Apotex ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 315.25 Td (have ) Tj ET Q q 0 0 0 rg BT 56.43 315.25 Td (settled ) Tj ET Q q 0 0 0 rg BT 84.09 315.25 Td (the ) Tj ET Q q 0 0 0 rg BT 97.52 315.25 Td (Apotex ) Tj ET Q q 0 0 0 rg BT 128.51 315.25 Td (case, ) Tj ET Q q 0 0 0 rg BT 149.77 315.25 Td (and ) Tj ET Q q 0 0 0 rg BT 165.76 315.25 Td (the ) Tj ET Q q 0 0 0 rg BT 179.53 315.25 Td (case ) Tj ET Q q 0 0 0 rg BT 198.30 315.25 Td (was ) Tj ET Q q 0 0 0 rg BT 215.40 315.25 Td (dismissed. ) Tj ET Q q 0 0 0 rg BT 258.79 315.25 Td (The ) Tj ET Q q 0 0 0 rg BT 275.55 315.25 Td (Australian ) Tj ET Q q 0 0 0 rg BT 318.76 315.25 Td (government ) Tj ET Q q 0 0 0 rg BT 368.08 315.25 Td (has ) Tj ET Q q 0 0 0 rg BT 382.96 315.25 Td (intervened ) Tj ET Q q 0 0 0 rg BT 426.72 315.25 Td (in ) Tj ET Q q 0 0 0 rg BT 436.05 315.25 Td (this ) Tj ET Q q 0 0 0 rg BT 452.05 315.25 Td (matter ) Tj ET Q q 0 0 0 rg BT 479.15 315.25 Td (and ) Tj ET Q q 0 0 0 rg BT 495.14 315.25 Td (is ) Tj ET Q q 0 0 0 rg BT 503.37 315.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 535.47 315.25 Td (maximum ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 303.25 Td (damages ) Tj ET Q q 0 0 0 rg BT 73.25 303.25 Td (up ) Tj ET Q q 0 0 0 rg BT 85.51 303.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 95.55 303.25 Td (449 ) Tj ET Q q 0 0 0 rg BT 112.82 303.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 141.71 303.25 Td ( ) Tj ET Q q 0 0 0 rg BT 143.47 303.25 Td (AUD ) Tj ET Q q 0 0 0 rg BT 167.40 303.25 Td (\() Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 170.73 303.25 Td ($346 ) Tj ET Q q 0 0 0 rg BT 192.99 303.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 221.88 303.25 Td (\), ) Tj ET Q q 0 0 0 rg BT 229.98 303.25 Td (plus ) Tj ET Q q 0 0 0 rg BT 248.91 303.25 Td (interest, ) Tj ET Q q 0 0 0 rg BT 283.11 303.25 Td (which ) Tj ET Q q 0 0 0 rg BT 309.81 303.25 Td (would ) Tj ET Q q 0 0 0 rg BT 337.07 303.25 Td (be ) Tj ET Q q 0 0 0 rg BT 348.77 303.25 Td (split ) Tj ET Q q 0 0 0 rg BT 368.26 303.25 Td (between ) Tj ET Q q 0 0 0 rg BT 403.84 303.25 Td (the ) Tj ET Q q 0 0 0 rg BT 418.32 303.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 459.47 303.25 Td (and ) Tj ET Q q 0 0 0 rg BT 476.17 303.25 Td (Sanofi, ) Tj ET Q q 0 0 0 rg BT 507.05 303.25 Td (for ) Tj ET Q q 0 0 0 rg BT 520.97 303.25 Td (alleged ) Tj ET Q q 0 0 0 rg BT 552.10 303.25 Td (losses ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 291.25 Td (experienced ) Tj ET Q q 0 0 0 rg BT 86.84 291.25 Td (for ) Tj ET Q q 0 0 0 rg BT 101.05 291.25 Td (paying ) Tj ET Q q 0 0 0 rg BT 130.81 291.25 Td (a ) Tj ET Q q 0 0 0 rg BT 137.79 291.25 Td (higher ) Tj ET Q q 0 0 0 rg BT 165.88 291.25 Td (price ) Tj ET Q q 0 0 0 rg BT 188.41 291.25 Td (for ) Tj ET Q q 0 0 0 rg BT 202.62 291.25 Td (branded ) Tj ET Q q 0 0 0 rg BT 237.37 291.25 Td (Plavix ) Tj ET Q q 0 0 0 rg BT 265.47 291.25 Td (during ) Tj ET Q q 0 0 0 rg BT 294.12 291.25 Td (the ) Tj ET Q q 0 0 0 rg BT 308.88 291.25 Td (period ) Tj ET Q q 0 0 0 rg BT 336.97 291.25 Td (when ) Tj ET Q q 0 0 0 rg BT 361.18 291.25 Td (the ) Tj ET Q q 0 0 0 rg BT 375.94 291.25 Td (injunction ) Tj ET Q q 0 0 0 rg BT 419.03 291.25 Td (was ) Tj ET Q q 0 0 0 rg BT 437.13 291.25 Td (in ) Tj ET Q q 0 0 0 rg BT 447.45 291.25 Td (place. ) Tj ET Q q 0 0 0 rg BT 473.40 291.25 Td (The ) Tj ET Q q 0 0 0 rg BT 491.49 291.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 532.93 291.25 Td (and ) Tj ET Q q 0 0 0 rg BT 549.91 291.25 Td (Sanofi ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 279.25 Td (have ) Tj ET Q q 0 0 0 rg BT 57.01 279.25 Td (disputed ) Tj ET Q q 0 0 0 rg BT 93.03 279.25 Td (that ) Tj ET Q q 0 0 0 rg BT 110.16 279.25 Td (the ) Tj ET Q q 0 0 0 rg BT 124.04 279.25 Td (Australian ) Tj ET Q q 0 0 0 rg BT 167.84 279.25 Td (government ) Tj ET Q q 0 0 0 rg BT 217.73 279.25 Td (is ) Tj ET Q q 0 0 0 rg BT 226.54 279.25 Td (entitled ) Tj ET Q q 0 0 0 rg BT 258.67 279.25 Td (to ) Tj ET Q q 0 0 0 rg BT 268.58 279.25 Td (any ) Tj ET Q q 0 0 0 rg BT 285.15 279.25 Td (damages ) Tj ET Q q 0 0 0 rg BT 322.27 279.25 Td (and ) Tj ET Q q 0 0 0 rg BT 338.85 279.25 Td (the ) Tj ET Q q 0 0 0 rg BT 352.73 279.25 Td (Australian ) Tj ET Q q 0 0 0 rg BT 396.52 279.25 Td (government's ) Tj ET Q q 0 0 0 rg BT 452.11 279.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 476.46 279.25 Td (is ) Tj ET Q q 0 0 0 rg BT 485.26 279.25 Td (still ) Tj ET Q q 0 0 0 rg BT 502.40 279.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 536.75 279.25 Td (and ) Tj ET Q q 0 0 0 rg BT 553.33 279.25 Td (a ) Tj ET Q q 0 0 0 rg BT 559.90 279.25 Td (trial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 267.25 Td (was ) Tj ET Q q 0 0 0 rg BT 54.05 267.25 Td (concluded ) Tj ET Q q 0 0 0 rg BT 97.65 267.25 Td (in ) Tj ET Q q 0 0 0 rg BT 107.92 267.25 Td (September ) Tj ET Q q 0 0 0 rg BT 153.19 267.25 Td (2017. ) Tj ET Q q 0 0 0 rg BT 178.01 267.25 Td (The ) Tj ET Q q 0 0 0 rg BT 196.05 267.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 237.44 267.25 Td (is ) Tj ET Q q 0 0 0 rg BT 246.61 267.25 Td (expecting ) Tj ET Q q 0 0 0 rg BT 287.98 267.25 Td (a ) Tj ET Q q 0 0 0 rg BT 294.92 267.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 330.75 267.25 Td (in ) Tj ET Q q 0 0 0 rg BT 341.02 267.25 Td (2018.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 251.25 Td (Sprycel) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 66.55 251.25 Td ( ) Tj ET Q q 0 0 0 rg BT 69.05 251.25 Td (- ) Tj ET Q q 0 0 0 rg BT 74.88 251.25 Td (Eur) Tj ET Q q 0 0 0 rg BT 91.37 251.25 Td (opean ) Tj ET Q q 0 0 0 rg BT 119.43 251.25 Td (Union) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 235.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.76 235.25 Td (May ) Tj ET Q q 0 0 0 rg BT 67.53 235.25 Td (2013, ) Tj ET Q q 0 0 0 rg BT 91.93 235.25 Td (Apotex, ) Tj ET Q q 0 0 0 rg BT 125.76 235.25 Td (Actavis ) Tj ET Q q 0 0 0 rg BT 158.74 235.25 Td (Group ) Tj ET Q q 0 0 0 rg BT 186.73 235.25 Td (PTC ) Tj ET Q q 0 0 0 rg BT 207.50 235.25 Td (ehf, ) Tj ET Q q 0 0 0 rg BT 225.20 235.25 Td (Generics ) Tj ET Q q 0 0 0 rg BT 263.18 235.25 Td ([UK] ) Tj ET Q q 0 0 0 rg BT 286.71 235.25 Td (Limited ) Tj ET Q q 0 0 0 rg BT 320.81 235.25 Td (\(Mylan\) ) Tj ET Q q 0 0 0 rg BT 356.01 235.25 Td (and ) Tj ET Q q 0 0 0 rg BT 372.88 235.25 Td (an ) Tj ET Q q 0 0 0 rg BT 384.75 235.25 Td (unnamed ) Tj ET Q q 0 0 0 rg BT 423.84 235.25 Td (company ) Tj ET Q q 0 0 0 rg BT 462.93 235.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 483.69 235.25 Td (oppositions ) Tj ET Q q 0 0 0 rg BT 532.25 235.25 Td (in ) Tj ET Q q 0 0 0 rg BT 542.46 235.25 Td (the ) Tj ET Q q 0 0 0 rg BT 557.11 235.25 Td (EPO ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 223.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 68.44 223.25 Td (revocation ) Tj ET Q q 0 0 0 rg BT 112.54 223.25 Td (of ) Tj ET Q q 0 0 0 rg BT 122.76 223.25 Td (European ) Tj ET Q q 0 0 0 rg BT 162.97 223.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 189.86 223.25 Td (No. ) Tj ET Q q 0 0 0 rg BT 206.47 223.25 Td (1) Tj ET Q q 0 0 0 rg BT 211.10 223.25 Td (169038 ) Tj ET Q q 0 0 0 rg BT 243.00 223.25 Td (\(the ) Tj ET Q q 0 0 0 rg BT 260.44 223.25 Td (‘038 ) Tj ET Q q 0 0 0 rg BT 280.66 223.25 Td (patent\) ) Tj ET Q q 0 0 0 rg BT 310.32 223.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 347.20 223.25 Td (dasatinib, ) Tj ET Q q 0 0 0 rg BT 387.69 223.25 Td (the ) Tj ET Q q 0 0 0 rg BT 401.80 223.25 Td (active ) Tj ET Q q 0 0 0 rg BT 427.57 223.25 Td (ingredient ) Tj ET Q q 0 0 0 rg BT 470.00 223.25 Td (in ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 479.68 223.25 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.66 223.25 Td (. ) Tj ET Q q 0 0 0 rg BT 513.92 223.25 Td (The ) Tj ET Q q 0 0 0 rg BT 531.36 223.25 Td (‘038 ) Tj ET Q q 0 0 0 rg BT 551.58 223.25 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 211.25 Td (is ) Tj ET Q q 0 0 0 rg BT 45.64 211.25 Td (scheduled ) Tj ET Q q 0 0 0 rg BT 88.59 211.25 Td (to ) Tj ET Q q 0 0 0 rg BT 99.34 211.25 Td (expire ) Tj ET Q q 0 0 0 rg BT 127.29 211.25 Td (in ) Tj ET Q q 0 0 0 rg BT 137.38 211.25 Td (April ) Tj ET Q q 0 0 0 rg BT 161.46 211.25 Td (2020 ) Tj ET Q q 0 0 0 rg BT 184.42 211.25 Td (\(excluding ) Tj ET Q q 0 0 0 rg BT 230.16 211.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 268.11 211.25 Td (term ) Tj ET Q q 0 0 0 rg BT 289.41 211.25 Td (extensions\). ) Tj ET Q q 0 0 0 rg BT 340.42 211.25 Td (On ) Tj ET Q q 0 0 0 rg BT 355.61 211.25 Td (January ) Tj ET Q q 0 0 0 rg BT 389.68 211.25 Td (20, ) Tj ET Q q 0 0 0 rg BT 405.15 211.25 Td (2016, ) Tj ET Q q 0 0 0 rg BT 430.61 211.25 Td (the ) Tj ET Q q 0 0 0 rg BT 445.80 211.25 Td (Opposition ) Tj ET Q q 0 0 0 rg BT 493.21 211.25 Td (Division ) Tj ET Q q 0 0 0 rg BT 530.63 211.25 Td (of ) Tj ET Q q 0 0 0 rg BT 541.93 211.25 Td (the ) Tj ET Q q 0 0 0 rg BT 557.11 211.25 Td (EPO ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 199.25 Td (revoked ) Tj ET Q q 0 0 0 rg BT 71.02 199.25 Td (the ) Tj ET Q q 0 0 0 rg BT 86.05 199.25 Td (‘038 ) Tj ET Q q 0 0 0 rg BT 107.19 199.25 Td (patent. ) Tj ET Q q 0 0 0 rg BT 136.94 199.25 Td (In ) Tj ET Q q 0 0 0 rg BT 148.08 199.25 Td (May ) Tj ET Q q 0 0 0 rg BT 169.22 199.25 Td (2016, ) Tj ET Q q 0 0 0 rg BT 194.54 199.25 Td (the ) Tj ET Q q 0 0 0 rg BT 209.56 199.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 251.26 199.25 Td (appealed ) Tj ET Q q 0 0 0 rg BT 289.61 199.25 Td (the ) Tj ET Q q 0 0 0 rg BT 304.64 199.25 Td (EPO’) Tj ET Q q 0 0 0 rg BT 326.31 199.25 Td (s ) Tj ET Q q 0 0 0 rg BT 333.01 199.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 369.15 199.25 Td (to ) Tj ET Q q 0 0 0 rg BT 379.74 199.25 Td (the ) Tj ET Q q 0 0 0 rg BT 394.77 199.25 Td (EPO ) Tj ET Q q 0 0 0 rg BT 416.47 199.25 Td (Board ) Tj ET Q q 0 0 0 rg BT 443.72 199.25 Td (of ) Tj ET Q q 0 0 0 rg BT 454.25 199.25 Td (Appeal. ) Tj ET Q q 0 0 0 rg BT 488.44 199.25 Td (In ) Tj ET Q q 0 0 0 rg BT 499.58 199.25 Td (February ) Tj ET Q q 0 0 0 rg BT 538.49 199.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 563.80 199.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 187.25 Td (EPO ) Tj ET Q q 0 0 0 rg BT 56.40 187.25 Td (Board ) Tj ET Q q 0 0 0 rg BT 82.35 187.25 Td (of ) Tj ET Q q 0 0 0 rg BT 91.85 187.25 Td (Appeal ) Tj ET Q q 0 0 0 rg BT 122.24 187.25 Td (upheld ) Tj ET Q q 0 0 0 rg BT 150.96 187.25 Td (the ) Tj ET Q q 0 0 0 rg BT 164.68 187.25 Td (Opposition ) Tj ET Q q 0 0 0 rg BT 210.64 187.25 Td (Division's ) Tj ET Q q 0 0 0 rg BT 252.29 187.25 Td (decision, ) Tj ET Q q 0 0 0 rg BT 289.62 187.25 Td (and ) Tj ET Q q 0 0 0 rg BT 305.57 187.25 Td (revoked ) Tj ET Q q 0 0 0 rg BT 339.28 187.25 Td (the ) Tj ET Q q 0 0 0 rg BT 353.01 187.25 Td (‘038 ) Tj ET Q q 0 0 0 rg BT 372.85 187.25 Td (patent. ) Tj ET Q q 0 0 0 rg BT 401.29 187.25 Td (Orphan ) Tj ET Q q 0 0 0 rg BT 432.79 187.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 452.62 187.25 Td (exclusivity ) Tj ET Q q 0 0 0 rg BT 498.01 187.25 Td (and ) Tj ET Q q 0 0 0 rg BT 513.96 187.25 Td (data ) Tj ET Q q 0 0 0 rg BT 532.12 187.25 Td (exclusivity ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 175.25 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 50.23 175.25 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 80.21 175.25 Td ( ) Tj ET Q q 0 0 0 rg BT 82.78 175.25 Td (in ) Tj ET Q q 0 0 0 rg BT 93.12 175.25 Td (the ) Tj ET Q q 0 0 0 rg BT 107.90 175.25 Td (EU ) Tj ET Q q 0 0 0 rg BT 123.80 175.25 Td (expired ) Tj ET Q q 0 0 0 rg BT 156.35 175.25 Td (in ) Tj ET Q q 0 0 0 rg BT 166.70 175.25 Td (November ) Tj ET Q q 0 0 0 rg BT 211.47 175.25 Td (2016. ) Tj ET Q q 0 0 0 rg BT 236.35 175.25 Td (The ) Tj ET Q q 0 0 0 rg BT 254.46 175.25 Td (EPO ) Tj ET Q q 0 0 0 rg BT 275.92 175.25 Td (Board ) Tj ET Q q 0 0 0 rg BT 302.92 175.25 Td (of ) Tj ET Q q 0 0 0 rg BT 313.25 175.25 Td (Appeal's ) Tj ET Q q 0 0 0 rg BT 350.39 175.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 386.28 175.25 Td (does ) Tj ET Q q 0 0 0 rg BT 407.18 175.25 Td (not ) Tj ET Q q 0 0 0 rg BT 422.52 175.25 Td (af) Tj ET Q q 0 0 0 rg BT 430.11 175.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 447.66 175.25 Td (the ) Tj ET Q q 0 0 0 rg BT 462.44 175.25 Td (validity ) Tj ET Q q 0 0 0 rg BT 495.56 175.25 Td (of ) Tj ET Q q 0 0 0 rg BT 506.46 175.25 Td (our ) Tj ET Q q 0 0 0 rg BT 522.35 175.25 Td (other ) Tj ET Q q 0 0 0 rg BT 545.47 175.25 Td (Sprycel ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 163.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 66.97 163.25 Td (within ) Tj ET Q q 0 0 0 rg BT 95.17 163.25 Td (and ) Tj ET Q q 0 0 0 rg BT 112.25 163.25 Td (outside ) Tj ET Q q 0 0 0 rg BT 143.77 163.25 Td (Europe, ) Tj ET Q q 0 0 0 rg BT 177.79 163.25 Td (including ) Tj ET Q q 0 0 0 rg BT 218.21 163.25 Td (dif) Tj ET Q q 0 0 0 rg BT 229.13 163.25 Td (ferent ) Tj ET Q q 0 0 0 rg BT 255.09 163.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 286.06 163.25 Td (that ) Tj ET Q q 0 0 0 rg BT 303.70 163.25 Td (cover ) Tj ET Q q 0 0 0 rg BT 328.54 163.25 Td (the ) Tj ET Q q 0 0 0 rg BT 343.40 163.25 Td (monohydrate ) Tj ET Q q 0 0 0 rg BT 398.81 163.25 Td (form ) Tj ET Q q 0 0 0 rg BT 420.89 163.25 Td (of ) Tj ET Q q 0 0 0 rg BT 431.86 163.25 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 470.60 163.25 Td (and ) Tj ET Q q 0 0 0 rg BT 487.68 163.25 Td (the ) Tj ET Q q 0 0 0 rg BT 502.54 163.25 Td (use ) Tj ET Q q 0 0 0 rg BT 518.51 163.25 Td (of ) Tj ET Q q 0 0 0 rg BT 529.49 163.25 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 568.23 163.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 151.25 Td (treat ) Tj ET Q q 0 0 0 rg BT 56.16 151.25 Td (CML. ) Tj ET Q q 0 0 0 rg BT 82.19 151.25 Td (Additionally) Tj ET Q q 0 0 0 rg BT 132.09 151.25 Td (, ) Tj ET Q q 0 0 0 rg BT 136.99 151.25 Td (in ) Tj ET Q q 0 0 0 rg BT 147.16 151.25 Td (February ) Tj ET Q q 0 0 0 rg BT 185.65 151.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 210.54 151.25 Td (the ) Tj ET Q q 0 0 0 rg BT 225.15 151.25 Td (EPO ) Tj ET Q q 0 0 0 rg BT 246.43 151.25 Td (Board ) Tj ET Q q 0 0 0 rg BT 273.27 151.25 Td (of ) Tj ET Q q 0 0 0 rg BT 283.46 151.25 Td (Appeal ) Tj ET Q q 0 0 0 rg BT 314.73 151.25 Td (reversed ) Tj ET Q q 0 0 0 rg BT 350.99 151.25 Td (and ) Tj ET Q q 0 0 0 rg BT 367.82 151.25 Td (remanded ) Tj ET Q q 0 0 0 rg BT 409.64 151.25 Td (an ) Tj ET Q q 0 0 0 rg BT 421.47 151.25 Td (invalidity ) Tj ET Q q 0 0 0 rg BT 462.19 151.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 497.91 151.25 Td (on ) Tj ET Q q 0 0 0 rg BT 510.30 151.25 Td (European ) Tj ET Q q 0 0 0 rg BT 551.01 151.25 Td (Patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 139.25 Td (No. ) Tj ET Q q 0 0 0 rg BT 52.98 139.25 Td (1610780 ) Tj ET Q q 0 0 0 rg BT 90.25 139.25 Td (and ) Tj ET Q q 0 0 0 rg BT 106.95 139.25 Td (its ) Tj ET Q q 0 0 0 rg BT 118.66 139.25 Td (claim ) Tj ET Q q 0 0 0 rg BT 143.14 139.25 Td (to ) Tj ET Q q 0 0 0 rg BT 153.18 139.25 Td (the ) Tj ET Q q 0 0 0 rg BT 167.66 139.25 Td (use ) Tj ET Q q 0 0 0 rg BT 183.25 139.25 Td (of ) Tj ET Q q 0 0 0 rg BT 193.84 139.25 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 232.21 139.25 Td (to ) Tj ET Q q 0 0 0 rg BT 242.25 139.25 Td (treat ) Tj ET Q q 0 0 0 rg BT 262.28 139.25 Td (CML, ) Tj ET Q q 0 0 0 rg BT 288.71 139.25 Td (which ) Tj ET Q q 0 0 0 rg BT 315.41 139.25 Td (the ) Tj ET Q q 0 0 0 rg BT 329.89 139.25 Td (EPO's ) Tj ET Q q 0 0 0 rg BT 356.74 139.25 Td (Opposition ) Tj ET Q q 0 0 0 rg BT 403.45 139.25 Td (Division ) Tj ET Q q 0 0 0 rg BT 440.17 139.25 Td (had ) Tj ET Q q 0 0 0 rg BT 456.87 139.25 Td (revoked ) Tj ET Q q 0 0 0 rg BT 491.34 139.25 Td (in ) Tj ET Q q 0 0 0 rg BT 501.38 139.25 Td (October ) Tj ET Q q 0 0 0 rg BT 535.85 139.25 Td (2012. ) Tj ET Q q 0 0 0 rg BT 560.45 139.25 Td (The ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 127.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 77.71 127.25 Td (intends ) Tj ET Q q 0 0 0 rg BT 109.42 127.25 Td (to ) Tj ET Q q 0 0 0 rg BT 120.03 127.25 Td (take ) Tj ET Q q 0 0 0 rg BT 139.51 127.25 Td (appropriate ) Tj ET Q q 0 0 0 rg BT 187.86 127.25 Td (legal ) Tj ET Q q 0 0 0 rg BT 210.12 127.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 241.27 127.25 Td (to ) Tj ET Q q 0 0 0 rg BT 251.87 127.25 Td (protect ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 282.46 127.25 Td (Sprycel) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 312.45 127.25 Td (. ) Tj ET Q q 0 0 0 rg BT 317.57 127.25 Td (W) Tj ET Q q 0 0 0 rg BT 326.21 127.25 Td (e ) Tj ET Q q 0 0 0 rg BT 333.47 127.25 Td (may ) Tj ET Q q 0 0 0 rg BT 353.51 127.25 Td (experience ) Tj ET Q q 0 0 0 rg BT 399.64 127.25 Td (a ) Tj ET Q q 0 0 0 rg BT 406.90 127.25 Td (decline ) Tj ET Q q 0 0 0 rg BT 438.60 127.25 Td (in ) Tj ET Q q 0 0 0 rg BT 449.20 127.25 Td (European ) Tj ET Q q 0 0 0 rg BT 490.34 127.25 Td (revenues ) Tj ET Q q 0 0 0 rg BT 528.70 127.25 Td (in ) Tj ET Q q 0 0 0 rg BT 539.30 127.25 Td (the ) Tj ET Q q 0 0 0 rg BT 554.35 127.25 Td (event ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 115.25 Td (that ) Tj ET Q q 0 0 0 rg BT 53.50 115.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 85.42 115.25 Td (dasatinib ) Tj ET Q q 0 0 0 rg BT 124.02 115.25 Td (product ) Tj ET Q q 0 0 0 rg BT 157.07 115.25 Td (enters ) Tj ET Q q 0 0 0 rg BT 183.45 115.25 Td (the ) Tj ET Q q 0 0 0 rg BT 198.16 115.25 Td (market.) Tj ET Q endstream endobj 199 0 obj <> endobj 200 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 301.00 24.60 Td (99) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Anti-PD-1 ) Tj ET Q q 0 0 0 rg BT 81.83 749.25 Td (Antibody ) Tj ET Q q 0 0 0 rg BT 124.34 749.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 154.61 749.25 Td (Oppositions ) Tj ET Q q 0 0 0 rg BT 208.25 749.25 Td (and ) Tj ET Q q 0 0 0 rg BT 226.87 749.25 Td (Litigation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 733.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.84 733.25 Td (September ) Tj ET Q q 0 0 0 rg BT 92.12 733.25 Td (2015, ) Tj ET Q q 0 0 0 rg BT 117.13 733.25 Td (Dana-Farber ) Tj ET Q q 0 0 0 rg BT 170.17 733.25 Td (Cancer ) Tj ET Q q 0 0 0 rg BT 201.00 733.25 Td (Institute ) Tj ET Q q 0 0 0 rg BT 236.28 733.25 Td (\(Dana-Farber\) ) Tj ET Q q 0 0 0 rg BT 295.98 733.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 316.82 733.25 Td (a ) Tj ET Q q 0 0 0 rg BT 323.77 733.25 Td (complaint ) Tj ET Q q 0 0 0 rg BT 366.27 733.25 Td (in ) Tj ET Q q 0 0 0 rg BT 376.56 733.25 Td (Massachusetts ) Tj ET Q q 0 0 0 rg BT 436.84 733.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 467.11 733.25 Td (court ) Tj ET Q q 0 0 0 rg BT 490.17 733.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 523.23 733.25 Td (to ) Tj ET Q q 0 0 0 rg BT 533.52 733.25 Td (correct ) Tj ET Q q 0 0 0 rg BT 563.79 733.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 721.25 Td (inventorship ) Tj ET Q q 0 0 0 rg BT 88.99 721.25 Td (on ) Tj ET Q q 0 0 0 rg BT 101.98 721.25 Td (up ) Tj ET Q q 0 0 0 rg BT 114.98 721.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 125.75 721.25 Td (five) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 141.30 721.25 Td ( ) Tj ET Q q 0 0 0 rg BT 144.29 721.25 Td (related ) Tj ET Q q 0 0 0 rg BT 174.49 721.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 195.27 721.25 Td (patents ) Tj ET Q q 0 0 0 rg BT 226.59 721.25 Td (directed ) Tj ET Q q 0 0 0 rg BT 261.78 721.25 Td (to ) Tj ET Q q 0 0 0 rg BT 272.56 721.25 Td (methods ) Tj ET Q q 0 0 0 rg BT 309.44 721.25 Td (of ) Tj ET Q q 0 0 0 rg BT 320.76 721.25 Td (treating ) Tj ET Q q 0 0 0 rg BT 354.30 721.25 Td (cancer ) Tj ET Q q 0 0 0 rg BT 383.38 721.25 Td (using ) Tj ET Q q 0 0 0 rg BT 408.04 721.25 Td (PD-1 ) Tj ET Q q 0 0 0 rg BT 432.15 721.25 Td (and ) Tj ET Q q 0 0 0 rg BT 449.58 721.25 Td (PD-L1 ) Tj ET Q q 0 0 0 rg BT 479.80 721.25 Td (antibodies. ) Tj ET Q q 0 0 0 rg BT 526.40 721.25 Td (Specifically) Tj ET Q q 0 0 0 rg BT 573.51 721.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 709.25 Td (Dana-Farber ) Tj ET Q q 0 0 0 rg BT 89.03 709.25 Td (is ) Tj ET Q q 0 0 0 rg BT 98.21 709.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 131.27 709.25 Td (to ) Tj ET Q q 0 0 0 rg BT 141.55 709.25 Td (add ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 158.50 709.25 Td (two) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 173.50 709.25 Td ( ) Tj ET Q q 0 0 0 rg BT 176.00 709.25 Td (scientists ) Tj ET Q q 0 0 0 rg BT 215.18 709.25 Td (as ) Tj ET Q q 0 0 0 rg BT 226.01 709.25 Td (inventors ) Tj ET Q q 0 0 0 rg BT 265.74 709.25 Td (to ) Tj ET Q q 0 0 0 rg BT 276.02 709.25 Td (these ) Tj ET Q q 0 0 0 rg BT 299.08 709.25 Td (patents. ) Tj ET Q q 0 0 0 rg BT 332.41 709.25 Td (In ) Tj ET Q q 0 0 0 rg BT 343.25 709.25 Td (October ) Tj ET Q q 0 0 0 rg BT 377.96 709.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 402.97 709.25 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 429.35 709.25 Td (was ) Tj ET Q q 0 0 0 rg BT 447.41 709.25 Td (allowed ) Tj ET Q q 0 0 0 rg BT 481.58 709.25 Td (to ) Tj ET Q q 0 0 0 rg BT 491.86 709.25 Td (intervene ) Tj ET Q q 0 0 0 rg BT 531.57 709.25 Td (in ) Tj ET Q q 0 0 0 rg BT 541.86 709.25 Td (this ) Tj ET Q q 0 0 0 rg BT 558.81 709.25 Td (case ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 697.25 Td (alleging ) Tj ET Q q 0 0 0 rg BT 70.00 697.25 Td (that ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 86.78 697.25 Td (one) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 101.22 697.25 Td ( ) Tj ET Q q 0 0 0 rg BT 103.01 697.25 Td (of ) Tj ET Q q 0 0 0 rg BT 113.12 697.25 Td (the ) Tj ET Q q 0 0 0 rg BT 127.13 697.25 Td (scientists ) Tj ET Q q 0 0 0 rg BT 165.58 697.25 Td (identified ) Tj ET Q q 0 0 0 rg BT 205.69 697.25 Td (by ) Tj ET Q q 0 0 0 rg BT 217.47 697.25 Td (Dana-Farber ) Tj ET Q q 0 0 0 rg BT 269.79 697.25 Td (was ) Tj ET Q q 0 0 0 rg BT 287.13 697.25 Td (employed ) Tj ET Q q 0 0 0 rg BT 328.35 697.25 Td (by ) Tj ET Q q 0 0 0 rg BT 340.14 697.25 Td (a ) Tj ET Q q 0 0 0 rg BT 346.36 697.25 Td (company ) Tj ET Q q 0 0 0 rg BT 384.80 697.25 Td (eventually ) Tj ET Q q 0 0 0 rg BT 428.24 697.25 Td (acquired ) Tj ET Q q 0 0 0 rg BT 464.45 697.25 Td (by ) Tj ET Q q 0 0 0 rg BT 476.24 697.25 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 501.90 697.25 Td (during ) Tj ET Q q 0 0 0 rg BT 529.80 697.25 Td (the ) Tj ET Q q 0 0 0 rg BT 543.80 697.25 Td (relevant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 685.25 Td (period. ) Tj ET Q q 0 0 0 rg BT 66.72 685.25 Td (While ) Tj ET Q q 0 0 0 rg BT 94.04 685.25 Td (an ) Tj ET Q q 0 0 0 rg BT 106.36 685.25 Td (adverse ) Tj ET Q q 0 0 0 rg BT 139.78 685.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 175.99 685.25 Td (in ) Tj ET Q q 0 0 0 rg BT 186.65 685.25 Td (this ) Tj ET Q q 0 0 0 rg BT 203.98 685.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 242.97 685.25 Td (would ) Tj ET Q q 0 0 0 rg BT 270.86 685.25 Td (not ) Tj ET Q q 0 0 0 rg BT 286.52 685.25 Td (result ) Tj ET Q q 0 0 0 rg BT 311.62 685.25 Td (in ) Tj ET Q q 0 0 0 rg BT 322.28 685.25 Td (monetary ) Tj ET Q q 0 0 0 rg BT 362.93 685.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 396.92 685.25 Td (for ) Tj ET Q q 0 0 0 rg BT 411.46 685.25 Td (the ) Tj ET Q q 0 0 0 rg BT 426.56 685.25 Td (Company) Tj ET Q q 0 0 0 rg BT 464.80 685.25 Td (, ) Tj ET Q q 0 0 0 rg BT 470.18 685.25 Td (it ) Tj ET Q q 0 0 0 rg BT 478.62 685.25 Td (could ) Tj ET Q q 0 0 0 rg BT 503.72 685.25 Td (decrease ) Tj ET Q q 0 0 0 rg BT 541.02 685.25 Td (potential ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 673.25 Td (future ) Tj ET Q q 0 0 0 rg BT 62.38 673.25 Td (licensing ) Tj ET Q q 0 0 0 rg BT 100.98 673.25 Td (revenue ) Tj ET Q q 0 0 0 rg BT 135.13 673.25 Td (from ) Tj ET Q q 0 0 0 rg BT 157.06 673.25 Td (these ) Tj ET Q q 0 0 0 rg BT 180.11 673.25 Td (patents.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 657.25 Td (Eliquis) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 65.46 657.25 Td ( ) Tj ET Q q 0 0 0 rg BT 67.96 657.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 98.23 657.25 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 142.95 657.25 Td (- ) Tj ET Q q 0 0 0 rg BT 148.78 657.25 Td (U.S.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (In ) Tj ET Q q 0 0 0 rg BT 46.71 641.25 Td (2017, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 71.60 641.25 Td (twenty-five) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 117.69 641.25 Td ( generic ) Tj ET Q q 0 0 0 rg BT 152.00 641.25 Td (companies ) Tj ET Q q 0 0 0 rg BT 197.14 641.25 Td (sent ) Tj ET Q q 0 0 0 rg BT 215.63 641.25 Td (the ) Tj ET Q q 0 0 0 rg BT 230.23 641.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 271.50 641.25 Td (Paragraph-IV) Tj ET Q q 0 0 0 rg BT 325.74 641.25 Td ( ) Tj ET Q q 0 0 0 rg BT 328.12 641.25 Td (certification ) Tj ET Q q 0 0 0 rg BT 378.81 641.25 Td (letters ) Tj ET Q q 0 0 0 rg BT 405.63 641.25 Td (informing ) Tj ET Q q 0 0 0 rg BT 448.01 641.25 Td (the ) Tj ET Q q 0 0 0 rg BT 462.61 641.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 503.88 641.25 Td (that ) Tj ET Q q 0 0 0 rg BT 521.25 641.25 Td (they ) Tj ET Q q 0 0 0 rg BT 540.85 641.25 Td (had ) Tj ET Q q 0 0 0 rg BT 557.67 641.25 Td (filed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (abbreviated ) Tj ET Q q 0 0 0 rg BT 84.82 629.25 Td (new ) Tj ET Q q 0 0 0 rg BT 103.65 629.25 Td (drug ) Tj ET Q q 0 0 0 rg BT 124.16 629.25 Td (applications ) Tj ET Q q 0 0 0 rg BT 174.66 629.25 Td (\(aNDAs\) ) Tj ET Q q 0 0 0 rg BT 213.49 629.25 Td (seeking ) Tj ET Q q 0 0 0 rg BT 246.21 629.25 Td (approval ) Tj ET Q q 0 0 0 rg BT 283.38 629.25 Td (of ) Tj ET Q q 0 0 0 rg BT 293.88 629.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 325.48 629.25 Td (versions ) Tj ET Q q 0 0 0 rg BT 360.99 629.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 371.82 629.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 400.16 629.25 Td (. ) Tj ET Q q 0 0 0 rg BT 404.35 629.25 Td (As ) Tj ET Q q 0 0 0 rg BT 417.64 629.25 Td (a ) Tj ET Q q 0 0 0 rg BT 424.26 629.25 Td (result, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 451.15 629.25 Td (two) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 466.15 629.25 Td ( ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 468.65 629.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.99 629.25 Td ( patents ) Tj ET Q q 0 0 0 rg BT 529.99 629.25 Td (listed ) Tj ET Q q 0 0 0 rg BT 553.83 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 563.78 629.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (FDA) Tj ET Q q 0 0 0 rg BT 55.45 617.25 Td ( ) Tj ET Q q 0 0 0 rg BT 58.26 617.25 Td (Orange ) Tj ET Q q 0 0 0 rg BT 90.49 617.25 Td (Book ) Tj ET Q q 0 0 0 rg BT 114.96 617.25 Td (are ) Tj ET Q q 0 0 0 rg BT 129.97 617.25 Td (being ) Tj ET Q q 0 0 0 rg BT 154.99 617.25 Td (challenged: ) Tj ET Q q 0 0 0 rg BT 203.88 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 218.90 617.25 Td (composition ) Tj ET Q q 0 0 0 rg BT 271.15 617.25 Td (of ) Tj ET Q q 0 0 0 rg BT 282.28 617.25 Td (matter ) Tj ET Q q 0 0 0 rg BT 310.62 617.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 337.86 617.25 Td (claiming ) Tj ET Q q 0 0 0 rg BT 375.65 617.25 Td (apixaban ) Tj ET Q q 0 0 0 rg BT 414.55 617.25 Td (specifically ) Tj ET Q q 0 0 0 rg BT 463.44 617.25 Td (and ) Tj ET Q q 0 0 0 rg BT 480.68 617.25 Td (a ) Tj ET Q q 0 0 0 rg BT 487.92 617.25 Td (formulation ) Tj ET Q q 0 0 0 rg BT 537.94 617.25 Td (patent. ) Tj ET Q q 0 0 0 rg BT 567.67 617.25 Td (In ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (April ) Tj ET Q q 0 0 0 rg BT 59.75 605.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 84.88 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 99.74 605.25 Td (Company) Tj ET Q q 0 0 0 rg BT 137.97 605.25 Td (, ) Tj ET Q q 0 0 0 rg BT 143.11 605.25 Td (along ) Tj ET Q q 0 0 0 rg BT 167.96 605.25 Td (with ) Tj ET Q q 0 0 0 rg BT 188.38 605.25 Td (its ) Tj ET Q q 0 0 0 rg BT 200.46 605.25 Td (partner ) Tj ET Q q 0 0 0 rg BT 231.42 605.25 Td (Pfizer) Tj ET Q q 0 0 0 rg BT 254.89 605.25 Td (, ) Tj ET Q q 0 0 0 rg BT 260.03 605.25 Td (initiated ) Tj ET Q q 0 0 0 rg BT 295.43 605.25 Td (patent ) Tj ET Q q 0 0 0 rg BT 322.50 605.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 357.92 605.25 Td (under ) Tj ET Q q 0 0 0 rg BT 383.32 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 398.18 605.25 Td (Hatch-W) Tj ET Q q 0 0 0 rg BT 434.02 605.25 Td (axman ) Tj ET Q q 0 0 0 rg BT 462.73 605.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 479.81 605.25 Td (against ) Tj ET Q q 0 0 0 rg BT 510.77 605.25 Td (all ) Tj ET Q q 0 0 0 rg BT 523.40 605.25 Td (generic ) Tj ET Q q 0 0 0 rg BT 555.46 605.25 Td (filers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 593.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.40 593.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 76.77 593.25 Td (district ) Tj ET Q q 0 0 0 rg BT 107.16 593.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 134.21 593.25 Td (in ) Tj ET Q q 0 0 0 rg BT 144.61 593.25 Td (Delaware ) Tj ET Q q 0 0 0 rg BT 185.53 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 202.40 593.25 Td (W) Tj ET Q q 0 0 0 rg BT 211.04 593.25 Td (est ) Tj ET Q q 0 0 0 rg BT 224.57 593.25 Td (V) Tj ET Q q 0 0 0 rg BT 231.19 593.25 Td (ir) Tj ET Q q 0 0 0 rg BT 237.12 593.25 Td (ginia. ) Tj ET Q q 0 0 0 rg BT 262.23 593.25 Td (In ) Tj ET Q q 0 0 0 rg BT 272.60 593.25 Td (August ) Tj ET Q q 0 0 0 rg BT 304.11 593.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 329.23 593.25 Td (the ) Tj ET Q q 0 0 0 rg BT 344.06 593.25 Td (United ) Tj ET Q q 0 0 0 rg BT 373.90 593.25 Td (States ) Tj ET Q q 0 0 0 rg BT 400.40 593.25 Td (Patent ) Tj ET Q q 0 0 0 rg BT 428.01 593.25 Td (and ) Tj ET Q q 0 0 0 rg BT 444.88 593.25 Td (T) Tj ET Q q 0 0 0 rg BT 450.64 593.25 Td (rademark ) Tj ET Q q 0 0 0 rg BT 491.01 593.25 Td (Of) Tj ET Q q 0 0 0 rg BT 501.38 593.25 Td (fice ) Tj ET Q q 0 0 0 rg BT 518.98 593.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 551.58 593.25 Td (patent ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 581.25 Td (term ) Tj ET Q q 0 0 0 rg BT 56.70 581.25 Td (restoration ) Tj ET Q q 0 0 0 rg BT 101.84 581.25 Td (to ) Tj ET Q q 0 0 0 rg BT 111.99 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 126.59 581.25 Td (composition ) Tj ET Q q 0 0 0 rg BT 178.40 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 189.11 581.25 Td (matter ) Tj ET Q q 0 0 0 rg BT 217.03 581.25 Td (patent, ) Tj ET Q q 0 0 0 rg BT 246.34 581.25 Td (thereby ) Tj ET Q q 0 0 0 rg BT 278.70 581.25 Td (restoring ) Tj ET Q q 0 0 0 rg BT 316.62 581.25 Td (the ) Tj ET Q q 0 0 0 rg BT 331.21 581.25 Td (term ) Tj ET Q q 0 0 0 rg BT 351.91 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 362.62 581.25 Td (the ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 377.34 581.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 405.67 581.25 Td ( composition ) Tj ET Q q 0 0 0 rg BT 459.99 581.25 Td (of ) Tj ET Q q 0 0 0 rg BT 470.69 581.25 Td (matter ) Tj ET Q q 0 0 0 rg BT 498.61 581.25 Td (patent, ) Tj ET Q q 0 0 0 rg BT 527.92 581.25 Td (which ) Tj ET Q q 0 0 0 rg BT 554.74 581.25 Td (is ) Tj ET Q q 0 0 0 rg BT 563.78 581.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 569.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 77.67 569.25 Td (s ) Tj ET Q q 0 0 0 rg BT 83.50 569.25 Td (basis ) Tj ET Q q 0 0 0 rg BT 105.44 569.25 Td (for ) Tj ET Q q 0 0 0 rg BT 119.05 569.25 Td (projected ) Tj ET Q q 0 0 0 rg BT 158.19 569.25 Td (LOE, ) Tj ET Q q 0 0 0 rg BT 182.07 569.25 Td (from ) Tj ET Q q 0 0 0 rg BT 203.46 569.25 Td (February ) Tj ET Q q 0 0 0 rg BT 241.50 569.25 Td (2023 ) Tj ET Q q 0 0 0 rg BT 263.44 569.25 Td (to ) Tj ET Q q 0 0 0 rg BT 273.16 569.25 Td (November ) Tj ET Q q 0 0 0 rg BT 317.31 569.25 Td (2026. ) Tj ET Q q 0 0 0 rg BT 341.62 569.25 Td (The ) Tj ET Q q 0 0 0 rg BT 359.11 569.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 399.94 569.25 Td (has ) Tj ET Q q 0 0 0 rg BT 415.21 569.25 Td (settled ) Tj ET Q q 0 0 0 rg BT 443.26 569.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 477.98 569.25 Td (with ) Tj ET Q q 0 0 0 rg BT 497.70 569.25 Td (several ) Tj ET Q q 0 0 0 rg BT 527.96 569.25 Td (aNDA) Tj ET Q q 0 0 0 rg BT 553.51 569.25 Td ( ) Tj ET Q q 0 0 0 rg BT 555.45 569.25 Td (filers ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 557.25 Td (through ) Tj ET Q q 0 0 0 rg BT 69.61 557.25 Td (February ) Tj ET Q q 0 0 0 rg BT 108.21 557.25 Td (2018. ) Tj ET Q q 0 0 0 rg BT 133.03 557.25 Td (The ) Tj ET Q q 0 0 0 rg BT 151.07 557.25 Td (settlements ) Tj ET Q q 0 0 0 rg BT 198.56 557.25 Td (do ) Tj ET Q q 0 0 0 rg BT 211.06 557.25 Td (not ) Tj ET Q q 0 0 0 rg BT 226.34 557.25 Td (af) Tj ET Q q 0 0 0 rg BT 233.93 557.25 Td (fect ) Tj ET Q q 0 0 0 rg BT 251.42 557.25 Td (the ) Tj ET Q q 0 0 0 rg BT 266.13 557.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 307.80 557.25 Td (s ) Tj ET Q q 0 0 0 rg BT 314.19 557.25 Td (projected ) Tj ET Q q 0 0 0 rg BT 353.89 557.25 Td (LOE ) Tj ET Q q 0 0 0 rg BT 375.83 557.25 Td (for ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 389.99 557.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 418.32 557.25 Td (.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 536.25 Td (PRICING, SALES ) Tj ET Q q 0 0 0 rg BT 117.97 536.25 Td (AND PROMOTIONAL) Tj ET Q q 0 0 0 rg BT 219.36 536.25 Td ( PRACTICES LITIGA) Tj ET Q q 0 0 0 rg BT 317.53 536.25 Td (TION) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 520.25 Td (Plavix*) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 67.10 520.25 Td ( ) Tj ET Q q 0 0 0 rg BT 69.60 520.25 Td (State ) Tj ET Q q 0 0 0 rg BT 93.21 520.25 Td (Attorneys ) Tj ET Q q 0 0 0 rg BT 137.92 520.25 Td (General ) Tj ET Q q 0 0 0 rg BT 174.86 520.25 Td (Lawsuits) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 504.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.07 504.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 95.48 504.25 Td (and ) Tj ET Q q 0 0 0 rg BT 112.44 504.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 142.16 504.25 Td (af) Tj ET Q q 0 0 0 rg BT 149.75 504.25 Td (filiates ) Tj ET Q q 0 0 0 rg BT 179.48 504.25 Td (of ) Tj ET Q q 0 0 0 rg BT 190.33 504.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 218.96 504.25 Td (are ) Tj ET Q q 0 0 0 rg BT 233.69 504.25 Td (defendants ) Tj ET Q q 0 0 0 rg BT 279.52 504.25 Td (in ) Tj ET Q q 0 0 0 rg BT 289.82 504.25 Td (consumer ) Tj ET Q q 0 0 0 rg BT 331.22 504.25 Td (protection ) Tj ET Q q 0 0 0 rg BT 374.28 504.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 402.35 504.25 Td (false ) Tj ET Q q 0 0 0 rg BT 423.75 504.25 Td (advertising ) Tj ET Q q 0 0 0 rg BT 470.70 504.25 Td (actions ) Tj ET Q q 0 0 0 rg BT 501.55 504.25 Td (brought ) Tj ET Q q 0 0 0 rg BT 535.18 504.25 Td (by ) Tj ET Q q 0 0 0 rg BT 547.70 504.25 Td (several ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 492.25 Td (states ) Tj ET Q q 0 0 0 rg BT 60.72 492.25 Td (relating ) Tj ET Q q 0 0 0 rg BT 93.76 492.25 Td (to ) Tj ET Q q 0 0 0 rg BT 104.04 492.25 Td (the ) Tj ET Q q 0 0 0 rg BT 118.75 492.25 Td (sales ) Tj ET Q q 0 0 0 rg BT 140.69 492.25 Td (and ) Tj ET Q q 0 0 0 rg BT 157.63 492.25 Td (promotion ) Tj ET Q q 0 0 0 rg BT 201.80 492.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 212.63 492.25 Td (Plavix*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 243.17 492.25 Td (.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 476.25 Td (PRODUCT) Tj ET Q q 0 0 0 rg BT 85.26 476.25 Td ( ) Tj ET Q q 0 0 0 rg BT 87.76 476.25 Td (LIABILITY) Tj ET Q q 0 0 0 rg BT 140.19 476.25 Td ( ) Tj ET Q q 0 0 0 rg BT 142.69 476.25 Td (LITIGA) Tj ET Q q 0 0 0 rg BT 178.07 476.25 Td (TION) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 460.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.09 460.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 95.52 460.25 Td (is ) Tj ET Q q 0 0 0 rg BT 104.73 460.25 Td (a ) Tj ET Q q 0 0 0 rg BT 111.71 460.25 Td (party ) Tj ET Q q 0 0 0 rg BT 134.80 460.25 Td (to ) Tj ET Q q 0 0 0 rg BT 145.12 460.25 Td (various ) Tj ET Q q 0 0 0 rg BT 177.10 460.25 Td (product ) Tj ET Q q 0 0 0 rg BT 210.18 460.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 243.83 460.25 Td (lawsuits. ) Tj ET Q q 0 0 0 rg BT 281.65 460.25 Td (Plaintif) Tj ET Q q 0 0 0 rg BT 310.92 460.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 320.68 460.25 Td (in ) Tj ET Q q 0 0 0 rg BT 331.00 460.25 Td (these ) Tj ET Q q 0 0 0 rg BT 354.09 460.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 377.73 460.25 Td (seek ) Tj ET Q q 0 0 0 rg BT 398.04 460.25 Td (damages ) Tj ET Q q 0 0 0 rg BT 435.57 460.25 Td (and ) Tj ET Q q 0 0 0 rg BT 452.55 460.25 Td (other ) Tj ET Q q 0 0 0 rg BT 475.63 460.25 Td (relief ) Tj ET Q q 0 0 0 rg BT 499.27 460.25 Td (on ) Tj ET Q q 0 0 0 rg BT 511.81 460.25 Td (various ) Tj ET Q q 0 0 0 rg BT 543.79 460.25 Td (grounds ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 448.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.40 448.25 Td (alleged ) Tj ET Q q 0 0 0 rg BT 82.02 448.25 Td (personal ) Tj ET Q q 0 0 0 rg BT 118.64 448.25 Td (injury ) Tj ET Q q 0 0 0 rg BT 145.27 448.25 Td (and ) Tj ET Q q 0 0 0 rg BT 162.45 448.25 Td (economic ) Tj ET Q q 0 0 0 rg BT 204.07 448.25 Td (loss. ) Tj ET Q q 0 0 0 rg BT 224.26 448.25 Td (As ) Tj ET Q q 0 0 0 rg BT 238.12 448.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 283.08 448.25 Td (disclosed, ) Tj ET Q q 0 0 0 rg BT 325.54 448.25 Td (in ) Tj ET Q q 0 0 0 rg BT 336.06 448.25 Td (addition ) Tj ET Q q 0 0 0 rg BT 371.58 448.25 Td (to ) Tj ET Q q 0 0 0 rg BT 382.10 448.25 Td (lawsuits, ) Tj ET Q q 0 0 0 rg BT 420.12 448.25 Td (the ) Tj ET Q q 0 0 0 rg BT 435.08 448.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 476.71 448.25 Td (also ) Tj ET Q q 0 0 0 rg BT 495.56 448.25 Td (faces ) Tj ET Q q 0 0 0 rg BT 518.84 448.25 Td (unfiled ) Tj ET Q q 0 0 0 rg BT 549.91 448.25 Td (claims ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 436.25 Td (involving ) Tj ET Q q 0 0 0 rg BT 76.83 436.25 Td (its ) Tj ET Q q 0 0 0 rg BT 88.78 436.25 Td (products.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 420.25 Td (Plavix*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 404.25 Td (As ) Tj ET Q q 0 0 0 rg BT 49.59 404.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 94.28 404.25 Td (disclosed, ) Tj ET Q q 0 0 0 rg BT 136.47 404.25 Td (the ) Tj ET Q q 0 0 0 rg BT 151.16 404.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 192.52 404.25 Td (and ) Tj ET Q q 0 0 0 rg BT 209.44 404.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 239.11 404.25 Td (af) Tj ET Q q 0 0 0 rg BT 246.70 404.25 Td (filiates ) Tj ET Q q 0 0 0 rg BT 276.39 404.25 Td (of ) Tj ET Q q 0 0 0 rg BT 287.19 404.25 Td (Sanofi ) Tj ET Q q 0 0 0 rg BT 315.78 404.25 Td (are ) Tj ET Q q 0 0 0 rg BT 330.46 404.25 Td (defendants ) Tj ET Q q 0 0 0 rg BT 376.25 404.25 Td (in ) Tj ET Q q 0 0 0 rg BT 386.50 404.25 Td (a ) Tj ET Q q 0 0 0 rg BT 393.41 404.25 Td (number ) Tj ET Q q 0 0 0 rg BT 426.43 404.25 Td (of ) Tj ET Q q 0 0 0 rg BT 437.24 404.25 Td (individual ) Tj ET Q q 0 0 0 rg BT 480.27 404.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 515.52 404.25 Td (in ) Tj ET Q q 0 0 0 rg BT 525.77 404.25 Td (various ) Tj ET Q q 0 0 0 rg BT 557.68 404.25 Td (state ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 392.25 Td (and ) Tj ET Q q 0 0 0 rg BT 52.55 392.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 82.42 392.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 108.97 392.25 Td (claiming ) Tj ET Q q 0 0 0 rg BT 146.07 392.25 Td (personal ) Tj ET Q q 0 0 0 rg BT 182.06 392.25 Td (injury ) Tj ET Q q 0 0 0 rg BT 208.06 392.25 Td (damage ) Tj ET Q q 0 0 0 rg BT 241.26 392.25 Td (allegedly ) Tj ET Q q 0 0 0 rg BT 280.02 392.25 Td (sustained ) Tj ET Q q 0 0 0 rg BT 319.35 392.25 Td (after ) Tj ET Q q 0 0 0 rg BT 339.78 392.25 Td (using ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 363.56 392.25 Td (Plavix*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 394.10 392.25 Td (. ) Tj ET Q q 0 0 0 rg BT 398.71 392.25 Td (Over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.82 392.25 Td (5,000) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 443.32 392.25 Td ( ) Tj ET Q q 0 0 0 rg BT 445.43 392.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 473.64 392.25 Td (involving ) Tj ET Q q 0 0 0 rg BT 514.09 392.25 Td (injury ) Tj ET Q q 0 0 0 rg BT 540.09 392.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 568.79 392.25 Td (fs ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 380.25 Td (as ) Tj ET Q q 0 0 0 rg BT 46.72 380.25 Td (well ) Tj ET Q q 0 0 0 rg BT 66.33 380.25 Td (as ) Tj ET Q q 0 0 0 rg BT 77.04 380.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 105.54 380.25 Td (by ) Tj ET Q q 0 0 0 rg BT 117.93 380.25 Td (spouses ) Tj ET Q q 0 0 0 rg BT 151.43 380.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 179.36 380.25 Td (other ) Tj ET Q q 0 0 0 rg BT 202.30 380.25 Td (beneficiaries, ) Tj ET Q q 0 0 0 rg BT 258.27 380.25 Td (have ) Tj ET Q q 0 0 0 rg BT 279.54 380.25 Td (been ) Tj ET Q q 0 0 0 rg BT 300.80 380.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 321.52 380.25 Td (in ) Tj ET Q q 0 0 0 rg BT 331.68 380.25 Td (state ) Tj ET Q q 0 0 0 rg BT 352.40 380.25 Td (and ) Tj ET Q q 0 0 0 rg BT 369.23 380.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 399.37 380.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 426.20 380.25 Td (in ) Tj ET Q q 0 0 0 rg BT 436.36 380.25 Td (various ) Tj ET Q q 0 0 0 rg BT 468.19 380.25 Td (states ) Tj ET Q q 0 0 0 rg BT 492.80 380.25 Td (including ) Tj ET Q q 0 0 0 rg BT 532.96 380.25 Td (California, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 368.25 Td (New ) Tj ET Q q 0 0 0 rg BT 57.02 368.25 Td (Jersey) Tj ET Q q 0 0 0 rg BT 81.37 368.25 Td (, ) Tj ET Q q 0 0 0 rg BT 86.01 368.25 Td (Delaware ) Tj ET Q q 0 0 0 rg BT 126.46 368.25 Td (and ) Tj ET Q q 0 0 0 rg BT 143.04 368.25 Td (New ) Tj ET Q q 0 0 0 rg BT 163.74 368.25 Td (Y) Tj ET Q q 0 0 0 rg BT 169.96 368.25 Td (ork. ) Tj ET Q q 0 0 0 rg BT 187.94 368.25 Td (In ) Tj ET Q q 0 0 0 rg BT 198.41 368.25 Td (February ) Tj ET Q q 0 0 0 rg BT 236.65 368.25 Td (2013, ) Tj ET Q q 0 0 0 rg BT 261.29 368.25 Td (the ) Tj ET Q q 0 0 0 rg BT 275.65 368.25 Td (Judicial ) Tj ET Q q 0 0 0 rg BT 308.90 368.25 Td (Panel ) Tj ET Q q 0 0 0 rg BT 333.26 368.25 Td (on ) Tj ET Q q 0 0 0 rg BT 345.40 368.25 Td (Multidistrict ) Tj ET Q q 0 0 0 rg BT 397.54 368.25 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 439.12 368.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 471.25 368.25 Td (the ) Tj ET Q q 0 0 0 rg BT 485.61 368.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 526.64 368.25 Td (and ) Tj ET Q q 0 0 0 rg BT 543.22 368.25 Td (Sanofi’) Tj ET Q q 0 0 0 rg BT 572.11 368.25 Td (s ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 356.25 Td (motion ) Tj ET Q q 0 0 0 rg BT 67.19 356.25 Td (to ) Tj ET Q q 0 0 0 rg BT 77.82 356.25 Td (establish ) Tj ET Q q 0 0 0 rg BT 115.66 356.25 Td (a ) Tj ET Q q 0 0 0 rg BT 122.95 356.25 Td (multi-district ) Tj ET Q q 0 0 0 rg BT 178.02 356.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 216.98 356.25 Td (\(MDL\) ) Tj ET Q q 0 0 0 rg BT 248.71 356.25 Td (to ) Tj ET Q q 0 0 0 rg BT 259.34 356.25 Td (coordinate ) Tj ET Q q 0 0 0 rg BT 304.40 356.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 337.24 356.25 Td (pretrial ) Tj ET Q q 0 0 0 rg BT 368.96 356.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 420.13 356.25 Td (in ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 430.76 356.25 Td (Plavix*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 461.30 356.25 Td ( ) Tj ET Q q 0 0 0 rg BT 464.15 356.25 Td (product ) Tj ET Q q 0 0 0 rg BT 497.55 356.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 531.51 356.25 Td (and ) Tj ET Q q 0 0 0 rg BT 548.80 356.25 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 344.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 60.31 344.25 Td (in ) Tj ET Q q 0 0 0 rg BT 71.29 344.25 Td (New ) Tj ET Q q 0 0 0 rg BT 93.38 344.25 Td (Jersey ) Tj ET Q q 0 0 0 rg BT 121.58 344.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 154.77 344.25 Td (Court. ) Tj ET Q q 0 0 0 rg BT 183.26 344.25 Td (Following ) Tj ET Q q 0 0 0 rg BT 227.59 344.25 Td (the ) Tj ET Q q 0 0 0 rg BT 243.01 344.25 Td (United ) Tj ET Q q 0 0 0 rg BT 273.44 344.25 Td (States ) Tj ET Q q 0 0 0 rg BT 300.53 344.25 Td (Supreme ) Tj ET Q q 0 0 0 rg BT 339.29 344.25 Td (Court’) Tj ET Q q 0 0 0 rg BT 364.84 344.25 Td (s ) Tj ET Q q 0 0 0 rg BT 371.94 344.25 Td (June ) Tj ET Q q 0 0 0 rg BT 393.48 344.25 Td (2017 ) Tj ET Q q 0 0 0 rg BT 416.69 344.25 Td (reversal ) Tj ET Q q 0 0 0 rg BT 451.54 344.25 Td (of ) Tj ET Q q 0 0 0 rg BT 463.08 344.25 Td (a ) Tj ET Q q 0 0 0 rg BT 470.73 344.25 Td (California ) Tj ET Q q 0 0 0 rg BT 514.48 344.25 Td (Supreme ) Tj ET Q q 0 0 0 rg BT 553.23 344.25 Td (Court ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 332.25 Td (decision ) Tj ET Q q 0 0 0 rg BT 71.66 332.25 Td (that ) Tj ET Q q 0 0 0 rg BT 88.99 332.25 Td (had ) Tj ET Q q 0 0 0 rg BT 105.76 332.25 Td (held ) Tj ET Q q 0 0 0 rg BT 125.31 332.25 Td (that ) Tj ET Q q 0 0 0 rg BT 142.64 332.25 Td (the ) Tj ET Q q 0 0 0 rg BT 157.19 332.25 Td (California ) Tj ET Q q 0 0 0 rg BT 200.07 332.25 Td (state ) Tj ET Q q 0 0 0 rg BT 220.73 332.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 247.50 332.25 Td (can ) Tj ET Q q 0 0 0 rg BT 263.71 332.25 Td (exercise ) Tj ET Q q 0 0 0 rg BT 298.80 332.25 Td (personal ) Tj ET Q q 0 0 0 rg BT 335.01 332.25 Td (jurisdiction ) Tj ET Q q 0 0 0 rg BT 382.89 332.25 Td (over ) Tj ET Q q 0 0 0 rg BT 403.00 332.25 Td (the ) Tj ET Q q 0 0 0 rg BT 417.55 332.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 445.99 332.25 Td (of ) Tj ET Q q 0 0 0 rg BT 456.65 332.25 Td (non-California ) Tj ET Q q 0 0 0 rg BT 517.86 332.25 Td (residents, ) Tj ET Q q 0 0 0 rg BT 558.24 332.25 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 320.25 Td (3,300) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 58.50 320.25 Td ( ) Tj ET Q q 0 0 0 rg BT 61.13 320.25 Td (out-of-state ) Tj ET Q q 0 0 0 rg BT 109.86 320.25 Td (resident ) Tj ET Q q 0 0 0 rg BT 144.15 320.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 172.85 320.25 Td (fs' ) Tj ET Q q 0 0 0 rg BT 184.51 320.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 213.25 320.25 Td (\(including ) Tj ET Q q 0 0 0 rg BT 256.99 320.25 Td (spouses ) Tj ET Q q 0 0 0 rg BT 290.73 320.25 Td (and ) Tj ET Q q 0 0 0 rg BT 307.81 320.25 Td (beneficiaries\) ) Tj ET Q q 0 0 0 rg BT 364.85 320.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 409.70 320.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 444.55 320.25 Td (in ) Tj ET Q q 0 0 0 rg BT 454.96 320.25 Td (the ) Tj ET Q q 0 0 0 rg BT 469.82 320.25 Td (California ) Tj ET Q q 0 0 0 rg BT 512.99 320.25 Td (state ) Tj ET Q q 0 0 0 rg BT 533.95 320.25 Td (court ) Tj ET Q q 0 0 0 rg BT 557.13 320.25 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 308.25 Td (been ) Tj ET Q q 0 0 0 rg BT 56.83 308.25 Td (dismissed. ) Tj ET Q q 0 0 0 rg BT 100.73 308.25 Td (Some ) Tj ET Q q 0 0 0 rg BT 125.46 308.25 Td (number ) Tj ET Q q 0 0 0 rg BT 157.96 308.25 Td (of ) Tj ET Q q 0 0 0 rg BT 168.24 308.25 Td (these ) Tj ET Q q 0 0 0 rg BT 190.74 308.25 Td (California ) Tj ET Q q 0 0 0 rg BT 233.23 308.25 Td (non-resident ) Tj ET Q q 0 0 0 rg BT 285.17 308.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 313.87 308.25 Td (fs’) Tj ET Q q 0 0 0 rg BT 323.68 308.25 Td ( ) Tj ET Q q 0 0 0 rg BT 325.63 308.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 353.69 308.25 Td (may ) Tj ET Q q 0 0 0 rg BT 372.86 308.25 Td (be ) Tj ET Q q 0 0 0 rg BT 384.25 308.25 Td (re-filed ) Tj ET Q q 0 0 0 rg BT 415.63 308.25 Td (in ) Tj ET Q q 0 0 0 rg BT 425.36 308.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 455.06 308.25 Td (court. ) Tj ET Q q 0 0 0 rg BT 479.63 308.25 Td (After ) Tj ET Q q 0 0 0 rg BT 502.68 308.25 Td (the ) Tj ET Q q 0 0 0 rg BT 516.85 308.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 557.69 308.25 Td (filed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 296.25 Td (summary ) Tj ET Q q 0 0 0 rg BT 76.16 296.25 Td (judgment ) Tj ET Q q 0 0 0 rg BT 116.87 296.25 Td (motions ) Tj ET Q q 0 0 0 rg BT 152.03 296.25 Td (in ) Tj ET Q q 0 0 0 rg BT 162.75 296.25 Td (all ) Tj ET Q q 0 0 0 rg BT 175.68 296.25 Td (of ) Tj ET Q q 0 0 0 rg BT 186.95 296.25 Td (the ) Tj ET Q q 0 0 0 rg BT 202.11 296.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 245.59 296.25 Td (cases, ) Tj ET Q q 0 0 0 rg BT 272.12 296.25 Td (law ) Tj ET Q q 0 0 0 rg BT 289.50 296.25 Td (firms ) Tj ET Q q 0 0 0 rg BT 313.55 296.25 Td (representing ) Tj ET Q q 0 0 0 rg BT 365.91 296.25 Td (a ) Tj ET Q q 0 0 0 rg BT 373.29 296.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 410.11 296.25 Td (of ) Tj ET Q q 0 0 0 rg BT 421.38 296.25 Td (the ) Tj ET Q q 0 0 0 rg BT 436.53 296.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 480.01 296.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 504.05 296.25 Td (represented ) Tj ET Q q 0 0 0 rg BT 553.07 296.25 Td (to ) Tj ET Q q 0 0 0 rg BT 563.79 296.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 284.25 Td (various ) Tj ET Q q 0 0 0 rg BT 68.24 284.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 95.49 284.25 Td (that ) Tj ET Q q 0 0 0 rg BT 113.29 284.25 Td (they ) Tj ET Q q 0 0 0 rg BT 133.31 284.25 Td (will ) Tj ET Q q 0 0 0 rg BT 151.67 284.25 Td (withdraw ) Tj ET Q q 0 0 0 rg BT 192.25 284.25 Td (from ) Tj ET Q q 0 0 0 rg BT 214.49 284.25 Td (or ) Tj ET Q q 0 0 0 rg BT 225.62 284.25 Td (discontinue ) Tj ET Q q 0 0 0 rg BT 274.53 284.25 Td (all ) Tj ET Q q 0 0 0 rg BT 287.33 284.25 Td (or ) Tj ET Q q 0 0 0 rg BT 298.47 284.25 Td (most ) Tj ET Q q 0 0 0 rg BT 320.72 284.25 Td (of ) Tj ET Q q 0 0 0 rg BT 331.86 284.25 Td (their ) Tj ET Q q 0 0 0 rg BT 352.99 284.25 Td (cases. ) Tj ET Q q 0 0 0 rg BT 379.19 284.25 Td (The ) Tj ET Q q 0 0 0 rg BT 397.54 284.25 Td (resolution ) Tj ET Q q 0 0 0 rg BT 440.34 284.25 Td (of ) Tj ET Q q 0 0 0 rg BT 451.48 284.25 Td (these ) Tj ET Q q 0 0 0 rg BT 474.83 284.25 Td (remaining ) Tj ET Q q 0 0 0 rg BT 518.18 284.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 553.76 284.25 Td (is ) Tj ET Q q 0 0 0 rg BT 563.23 284.25 Td (not ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 272.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 74.03 272.25 Td (to ) Tj ET Q q 0 0 0 rg BT 84.31 272.25 Td (have ) Tj ET Q q 0 0 0 rg BT 105.69 272.25 Td (a ) Tj ET Q q 0 0 0 rg BT 112.63 272.25 Td (material ) Tj ET Q q 0 0 0 rg BT 147.88 272.25 Td (impact ) Tj ET Q q 0 0 0 rg BT 177.60 272.25 Td (on ) Tj ET Q q 0 0 0 rg BT 190.10 272.25 Td (the ) Tj ET Q q 0 0 0 rg BT 204.81 272.25 Td (Company) Tj ET Q q 0 0 0 rg BT 243.05 272.25 Td (.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 256.25 Td (Byetta*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 240.25 Td (Amylin, ) Tj ET Q q 0 0 0 rg BT 71.45 240.25 Td (a ) Tj ET Q q 0 0 0 rg BT 78.28 240.25 Td (former ) Tj ET Q q 0 0 0 rg BT 107.87 240.25 Td (subsidiary ) Tj ET Q q 0 0 0 rg BT 151.37 240.25 Td (of ) Tj ET Q q 0 0 0 rg BT 162.09 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 176.70 240.25 Td (Company) Tj ET Q q 0 0 0 rg BT 214.94 240.25 Td (, ) Tj ET Q q 0 0 0 rg BT 219.83 240.25 Td (and ) Tj ET Q q 0 0 0 rg BT 236.65 240.25 Td (Lilly ) Tj ET Q q 0 0 0 rg BT 258.49 240.25 Td (are ) Tj ET Q q 0 0 0 rg BT 273.08 240.25 Td (co-defendants ) Tj ET Q q 0 0 0 rg BT 331.56 240.25 Td (in ) Tj ET Q q 0 0 0 rg BT 341.73 240.25 Td (product ) Tj ET Q q 0 0 0 rg BT 374.66 240.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 408.16 240.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 446.66 240.25 Td (related ) Tj ET Q q 0 0 0 rg BT 476.25 240.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 486.42 240.25 Td (Byetta*.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 519.46 240.25 Td ( ) Tj ET Q q 0 0 0 rg BT 521.68 240.25 Td (T) Tj ET Q q 0 0 0 rg BT 527.09 240.25 Td (o ) Tj ET Q q 0 0 0 rg BT 534.48 240.25 Td (date, ) Tj ET Q q 0 0 0 rg BT 556.03 240.25 Td (there ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.25 Td (are ) Tj ET Q q 0 0 0 rg BT 50.32 228.25 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 70.20 228.25 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.20 228.25 Td ( ) Tj ET Q q 0 0 0 rg BT 87.31 228.25 Td (separate ) Tj ET Q q 0 0 0 rg BT 122.18 228.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 157.07 228.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 191.40 228.25 Td (on ) Tj ET Q q 0 0 0 rg BT 203.51 228.25 Td (behalf ) Tj ET Q q 0 0 0 rg BT 230.60 228.25 Td (of ) Tj ET Q q 0 0 0 rg BT 241.05 228.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.92 228.25 Td (2,000) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 323.42 228.25 Td ( ) Tj ET Q q 0 0 0 rg BT 325.53 228.25 Td (active ) Tj ET Q q 0 0 0 rg BT 351.51 228.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 380.21 228.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 389.55 228.25 Td (\(including ) Tj ET Q q 0 0 0 rg BT 432.76 228.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 467.09 228.25 Td (settlements\), ) Tj ET Q q 0 0 0 rg BT 520.02 228.25 Td (which ) Tj ET Q q 0 0 0 rg BT 546.57 228.25 Td (include ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.25 Td (injury ) Tj ET Q q 0 0 0 rg BT 61.80 216.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 90.50 216.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 99.64 216.25 Td (as ) Tj ET Q q 0 0 0 rg BT 109.88 216.25 Td (well ) Tj ET Q q 0 0 0 rg BT 129.01 216.25 Td (as ) Tj ET Q q 0 0 0 rg BT 139.25 216.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 167.27 216.25 Td (by ) Tj ET Q q 0 0 0 rg BT 179.18 216.25 Td (spouses ) Tj ET Q q 0 0 0 rg BT 212.21 216.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 239.67 216.25 Td (other ) Tj ET Q q 0 0 0 rg BT 262.13 216.25 Td (beneficiaries, ) Tj ET Q q 0 0 0 rg BT 317.62 216.25 Td (in ) Tj ET Q q 0 0 0 rg BT 327.31 216.25 Td (various ) Tj ET Q q 0 0 0 rg BT 358.66 216.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 385.01 216.25 Td (in ) Tj ET Q q 0 0 0 rg BT 394.71 216.25 Td (the ) Tj ET Q q 0 0 0 rg BT 408.84 216.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 428.11 216.25 Td (As ) Tj ET Q q 0 0 0 rg BT 441.14 216.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 485.27 216.25 Td (reported, ) Tj ET Q q 0 0 0 rg BT 522.99 216.25 Td (the ) Tj ET Q q 0 0 0 rg BT 537.12 216.25 Td (Company ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.25 Td (has ) Tj ET Q q 0 0 0 rg BT 51.69 204.25 Td (agreed ) Tj ET Q q 0 0 0 rg BT 80.70 204.25 Td (to ) Tj ET Q q 0 0 0 rg BT 90.84 204.25 Td (resolve ) Tj ET Q q 0 0 0 rg BT 122.08 204.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 151.65 204.25 Td (of ) Tj ET Q q 0 0 0 rg BT 162.34 204.25 Td (these ) Tj ET Q q 0 0 0 rg BT 185.25 204.25 Td (claims.  ) Tj ET Q q 0 0 0 rg BT 218.72 204.25 Td (Most ) Tj ET Q q 0 0 0 rg BT 241.64 204.25 Td (of ) Tj ET Q q 0 0 0 rg BT 252.34 204.25 Td (those ) Tj ET Q q 0 0 0 rg BT 275.81 204.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 304.28 204.25 Td (have ) Tj ET Q q 0 0 0 rg BT 325.52 204.25 Td (been, ) Tj ET Q q 0 0 0 rg BT 349.26 204.25 Td (or ) Tj ET Q q 0 0 0 rg BT 359.95 204.25 Td (are ) Tj ET Q q 0 0 0 rg BT 374.52 204.25 Td (in ) Tj ET Q q 0 0 0 rg BT 384.66 204.25 Td (the ) Tj ET Q q 0 0 0 rg BT 399.24 204.25 Td (process ) Tj ET Q q 0 0 0 rg BT 431.60 204.25 Td (of ) Tj ET Q q 0 0 0 rg BT 442.29 204.25 Td (being, ) Tj ET Q q 0 0 0 rg BT 469.37 204.25 Td (dismissed. ) Tj ET Q q 0 0 0 rg BT 513.51 204.25 Td (The ) Tj ET Q q 0 0 0 rg BT 531.42 204.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 567.67 204.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 192.25 Td (these ) Tj ET Q q 0 0 0 rg BT 59.17 192.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 82.88 192.25 Td (have ) Tj ET Q q 0 0 0 rg BT 104.38 192.25 Td (been ) Tj ET Q q 0 0 0 rg BT 125.87 192.25 Td (brought ) Tj ET Q q 0 0 0 rg BT 159.60 192.25 Td (by ) Tj ET Q q 0 0 0 rg BT 172.22 192.25 Td (individuals ) Tj ET Q q 0 0 0 rg BT 219.28 192.25 Td (who ) Tj ET Q q 0 0 0 rg BT 239.12 192.25 Td (allege ) Tj ET Q q 0 0 0 rg BT 265.61 192.25 Td (personal ) Tj ET Q q 0 0 0 rg BT 302.11 192.25 Td (injury ) Tj ET Q q 0 0 0 rg BT 328.61 192.25 Td (sustained ) Tj ET Q q 0 0 0 rg BT 368.45 192.25 Td (after ) Tj ET Q q 0 0 0 rg BT 389.38 192.25 Td (using ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 413.67 192.25 Td (Byetta*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 444.21 192.25 Td (, ) Tj ET Q q 0 0 0 rg BT 449.33 192.25 Td (primarily ) Tj ET Q q 0 0 0 rg BT 489.16 192.25 Td (pancreatic ) Tj ET Q q 0 0 0 rg BT 532.86 192.25 Td (cancer ) Tj ET Q q 0 0 0 rg BT 561.56 192.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 180.25 Td (pancreatitis, ) Tj ET Q q 0 0 0 rg BT 87.04 180.25 Td (and, ) Tj ET Q q 0 0 0 rg BT 106.43 180.25 Td (in ) Tj ET Q q 0 0 0 rg BT 116.66 180.25 Td (some ) Tj ET Q q 0 0 0 rg BT 140.21 180.25 Td (cases, ) Tj ET Q q 0 0 0 rg BT 166.26 180.25 Td (claiming ) Tj ET Q q 0 0 0 rg BT 203.70 180.25 Td (alleged ) Tj ET Q q 0 0 0 rg BT 235.03 180.25 Td (wrongful ) Tj ET Q q 0 0 0 rg BT 274.14 180.25 Td (death. ) Tj ET Q q 0 0 0 rg BT 300.56 180.25 Td (The ) Tj ET Q q 0 0 0 rg BT 318.56 180.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 354.89 180.25 Td (of ) Tj ET Q q 0 0 0 rg BT 365.67 180.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 389.22 180.25 Td (were ) Tj ET Q q 0 0 0 rg BT 411.10 180.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 445.77 180.25 Td (in ) Tj ET Q q 0 0 0 rg BT 456.00 180.25 Td (Federal ) Tj ET Q q 0 0 0 rg BT 488.43 180.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 513.66 180.25 Td (in ) Tj ET Q q 0 0 0 rg BT 523.89 180.25 Td (San ) Tj ET Q q 0 0 0 rg BT 541.34 180.25 Td (Diego ) Tj ET Q q 0 0 0 rg BT 568.23 180.25 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 168.25 Td (an ) Tj ET Q q 0 0 0 rg BT 47.70 168.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 69.55 168.25 Td ( ) Tj ET Q q 0 0 0 rg BT 71.82 168.25 Td (or ) Tj ET Q q 0 0 0 rg BT 82.42 168.25 Td (in ) Tj ET Q q 0 0 0 rg BT 92.46 168.25 Td (a ) Tj ET Q q 0 0 0 rg BT 99.16 168.25 Td (coordinated ) Tj ET Q q 0 0 0 rg BT 148.63 168.25 Td (proceeding ) Tj ET Q q 0 0 0 rg BT 195.32 168.25 Td (in ) Tj ET Q q 0 0 0 rg BT 205.37 168.25 Td (California ) Tj ET Q q 0 0 0 rg BT 248.17 168.25 Td (Superior ) Tj ET Q q 0 0 0 rg BT 284.88 168.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 309.92 168.25 Td (in ) Tj ET Q q 0 0 0 rg BT 319.96 168.25 Td (Los ) Tj ET Q q 0 0 0 rg BT 336.73 168.25 Td (Angeles ) Tj ET Q q 0 0 0 rg BT 371.76 168.25 Td (\(JCCP\). ) Tj ET Q q 0 0 0 rg BT 405.98 168.25 Td (In ) Tj ET Q q 0 0 0 rg BT 416.58 168.25 Td (November ) Tj ET Q q 0 0 0 rg BT 461.05 168.25 Td (2015, ) Tj ET Q q 0 0 0 rg BT 485.82 168.25 Td (the ) Tj ET Q q 0 0 0 rg BT 500.30 168.25 Td (defendants' ) Tj ET Q q 0 0 0 rg BT 547.68 168.25 Td (motion ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 156.25 Td (for ) Tj ET Q q 0 0 0 rg BT 50.15 156.25 Td (summary ) Tj ET Q q 0 0 0 rg BT 89.86 156.25 Td (judgment ) Tj ET Q q 0 0 0 rg BT 130.13 156.25 Td (based ) Tj ET Q q 0 0 0 rg BT 155.39 156.25 Td (on ) Tj ET Q q 0 0 0 rg BT 167.88 156.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 198.13 156.25 Td (preemption ) Tj ET Q q 0 0 0 rg BT 246.16 156.25 Td (was ) Tj ET Q q 0 0 0 rg BT 264.21 156.25 Td (granted ) Tj ET Q q 0 0 0 rg BT 296.69 156.25 Td (in ) Tj ET Q q 0 0 0 rg BT 306.96 156.25 Td (both ) Tj ET Q q 0 0 0 rg BT 327.23 156.25 Td (the ) Tj ET Q q 0 0 0 rg BT 341.94 156.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 363.79 156.25 Td ( ) Tj ET Q q 0 0 0 rg BT 366.28 156.25 Td (and ) Tj ET Q q 0 0 0 rg BT 383.21 156.25 Td (the ) Tj ET Q q 0 0 0 rg BT 397.92 156.25 Td (JCCP) Tj ET Q q 0 0 0 rg BT 419.61 156.25 Td (. ) Tj ET Q q 0 0 0 rg BT 424.42 156.25 Td (The ) Tj ET Q q 0 0 0 rg BT 442.46 156.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 471.16 156.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 480.87 156.25 Td (in ) Tj ET Q q 0 0 0 rg BT 491.14 156.25 Td (the ) Tj ET Q q 0 0 0 rg BT 505.85 156.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 527.70 156.25 Td ( ) Tj ET Q q 0 0 0 rg BT 530.20 156.25 Td (appealed ) Tj ET Q q 0 0 0 rg BT 568.22 156.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 144.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.86 144.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 71.29 144.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 96.71 144.25 Td (of ) Tj ET Q q 0 0 0 rg BT 107.10 144.25 Td (Appeals ) Tj ET Q q 0 0 0 rg BT 142.51 144.25 Td (for ) Tj ET Q q 0 0 0 rg BT 156.82 144.25 Td (the ) Tj ET Q q 0 0 0 rg BT 171.68 144.25 Td (Ninth ) Tj ET Q q 0 0 0 rg BT 197.10 144.25 Td (Circuit. ) Tj ET Q q 0 0 0 rg BT 230.02 144.25 Td (In ) Tj ET Q q 0 0 0 rg BT 240.99 144.25 Td (November ) Tj ET Q q 0 0 0 rg BT 285.84 144.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 310.99 144.25 Td (the ) Tj ET Q q 0 0 0 rg BT 325.85 144.25 Td (Ninth ) Tj ET Q q 0 0 0 rg BT 351.27 144.25 Td (Circuit ) Tj ET Q q 0 0 0 rg BT 381.69 144.25 Td (reversed ) Tj ET Q q 0 0 0 rg BT 418.20 144.25 Td (the ) Tj ET Q q 0 0 0 rg BT 433.06 144.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 454.91 144.25 Td ( ) Tj ET Q q 0 0 0 rg BT 457.56 144.25 Td (summary ) Tj ET Q q 0 0 0 rg BT 497.42 144.25 Td (judgment ) Tj ET Q q 0 0 0 rg BT 537.83 144.25 Td (order ) Tj ET Q q 0 0 0 rg BT 561.58 144.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 132.25 Td (remanded ) Tj ET Q q 0 0 0 rg BT 77.56 132.25 Td (the ) Tj ET Q q 0 0 0 rg BT 91.92 132.25 Td (case ) Tj ET Q q 0 0 0 rg BT 111.26 132.25 Td (for ) Tj ET Q q 0 0 0 rg BT 125.06 132.25 Td (further ) Tj ET Q q 0 0 0 rg BT 154.41 132.25 Td (proceedings. ) Tj ET Q q 0 0 0 rg BT 207.21 132.25 Td (The ) Tj ET Q q 0 0 0 rg BT 224.89 132.25 Td (JCCP) Tj ET Q q 0 0 0 rg BT 247.31 132.25 Td ( ) Tj ET Q q 0 0 0 rg BT 249.45 132.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 278.15 132.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 287.52 132.25 Td (have ) Tj ET Q q 0 0 0 rg BT 308.53 132.25 Td (appealed ) Tj ET Q q 0 0 0 rg BT 346.20 132.25 Td (to ) Tj ET Q q 0 0 0 rg BT 356.12 132.25 Td (the ) Tj ET Q q 0 0 0 rg BT 370.47 132.25 Td (California ) Tj ET Q q 0 0 0 rg BT 413.15 132.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 438.07 132.25 Td (of ) Tj ET Q q 0 0 0 rg BT 448.07 132.25 Td (Appeal ) Tj ET Q q 0 0 0 rg BT 479.08 132.25 Td (and ) Tj ET Q q 0 0 0 rg BT 495.66 132.25 Td (their ) Tj ET Q q 0 0 0 rg BT 516.13 132.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 544.36 132.25 Td (remains ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 120.25 Td (pending. ) Tj ET Q q 0 0 0 rg BT 72.83 120.25 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 106.09 120.25 Td (has ) Tj ET Q q 0 0 0 rg BT 122.13 120.25 Td (product ) Tj ET Q q 0 0 0 rg BT 155.38 120.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 189.19 120.25 Td (insurance ) Tj ET Q q 0 0 0 rg BT 230.22 120.25 Td (covering ) Tj ET Q q 0 0 0 rg BT 267.91 120.25 Td (a ) Tj ET Q q 0 0 0 rg BT 275.05 120.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 320.53 120.25 Td (number ) Tj ET Q q 0 0 0 rg BT 353.79 120.25 Td (of ) Tj ET Q q 0 0 0 rg BT 364.82 120.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 393.63 120.25 Td (involving ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 434.67 120.25 Td (Byetta*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 465.22 120.25 Td ( ) Tj ET Q q 0 0 0 rg BT 467.92 120.25 Td (and ) Tj ET Q q 0 0 0 rg BT 485.07 120.25 Td (any ) Tj ET Q q 0 0 0 rg BT 502.21 120.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 544.91 120.25 Td (liability ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 108.25 Td (to ) Tj ET Q q 0 0 0 rg BT 45.73 108.25 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 78.78 108.25 Td (with ) Tj ET Q q 0 0 0 rg BT 99.06 108.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 129.88 108.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 140.16 108.25 Td (Byetta*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 170.70 108.25 Td ( ) Tj ET Q q 0 0 0 rg BT 173.20 108.25 Td (is ) Tj ET Q q 0 0 0 rg BT 182.37 108.25 Td (expected ) Tj ET Q q 0 0 0 rg BT 220.40 108.25 Td (to ) Tj ET Q q 0 0 0 rg BT 230.68 108.25 Td (be ) Tj ET Q q 0 0 0 rg BT 242.62 108.25 Td (shared ) Tj ET Q q 0 0 0 rg BT 271.21 108.25 Td (between ) Tj ET Q q 0 0 0 rg BT 307.03 108.25 Td (the ) Tj ET Q q 0 0 0 rg BT 321.75 108.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 363.13 108.25 Td (and ) Tj ET Q q 0 0 0 rg BT 379.52 108.25 Td (AstraZeneca. ) Tj ET Q endstream endobj 201 0 obj <> endobj 202 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (100) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 733.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.48 733.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 96.30 733.25 Td (and ) Tj ET Q q 0 0 0 rg BT 113.68 733.25 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 144.94 733.25 Td (are ) Tj ET Q q 0 0 0 rg BT 160.08 733.25 Td (co-defendants ) Tj ET Q q 0 0 0 rg BT 219.10 733.25 Td (in ) Tj ET Q q 0 0 0 rg BT 229.81 733.25 Td (product ) Tj ET Q q 0 0 0 rg BT 263.29 733.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 297.34 733.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 336.38 733.25 Td (related ) Tj ET Q q 0 0 0 rg BT 366.52 733.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 377.23 733.25 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.89 733.25 Td (. ) Tj ET Q q 0 0 0 rg BT 414.33 733.25 Td (Plaintif) Tj ET Q q 0 0 0 rg BT 443.59 733.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 453.74 733.25 Td (allege ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 480.55 733.25 Td (Abilify*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.21 733.25 Td ( ) Tj ET Q q 0 0 0 rg BT 515.15 733.25 Td (caused ) Tj ET Q q 0 0 0 rg BT 545.29 733.25 Td (them ) Tj ET Q q 0 0 0 rg BT 568.22 733.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 721.25 Td (engage ) Tj ET Q q 0 0 0 rg BT 66.49 721.25 Td (in ) Tj ET Q q 0 0 0 rg BT 76.44 721.25 Td (compulsive ) Tj ET Q q 0 0 0 rg BT 124.72 721.25 Td (gambling ) Tj ET Q q 0 0 0 rg BT 164.66 721.25 Td (and ) Tj ET Q q 0 0 0 rg BT 181.27 721.25 Td (other ) Tj ET Q q 0 0 0 rg BT 203.99 721.25 Td (impulse ) Tj ET Q q 0 0 0 rg BT 237.83 721.25 Td (control ) Tj ET Q q 0 0 0 rg BT 268.33 721.25 Td (disorders. ) Tj ET Q q 0 0 0 rg BT 309.50 721.25 Td (There ) Tj ET Q q 0 0 0 rg BT 334.99 721.25 Td (have ) Tj ET Q q 0 0 0 rg BT 356.04 721.25 Td (been ) Tj ET Q q 0 0 0 rg BT 377.09 721.25 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 397.03 721.25 Td (500) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.03 721.25 Td ( ) Tj ET Q q 0 0 0 rg BT 414.21 721.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 437.48 721.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 457.98 721.25 Td (in ) Tj ET Q q 0 0 0 rg BT 467.93 721.25 Td (state ) Tj ET Q q 0 0 0 rg BT 488.43 721.25 Td (and ) Tj ET Q q 0 0 0 rg BT 505.04 721.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 534.96 721.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 561.58 721.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 709.25 Td (several ) Tj ET Q q 0 0 0 rg BT 66.45 709.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 108.58 709.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 131.82 709.25 Td (are ) Tj ET Q q 0 0 0 rg BT 146.16 709.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 180.52 709.25 Td (in ) Tj ET Q q 0 0 0 rg BT 190.43 709.25 Td (Canada. ) Tj ET Q q 0 0 0 rg BT 224.90 709.25 Td (The ) Tj ET Q q 0 0 0 rg BT 242.59 709.25 Td (Judicial ) Tj ET Q q 0 0 0 rg BT 275.83 709.25 Td (Panel ) Tj ET Q q 0 0 0 rg BT 300.18 709.25 Td (on ) Tj ET Q q 0 0 0 rg BT 312.32 709.25 Td (Multidistrict ) Tj ET Q q 0 0 0 rg BT 364.46 709.25 Td (Litigation ) Tj ET Q q 0 0 0 rg BT 406.03 709.25 Td (has ) Tj ET Q q 0 0 0 rg BT 421.50 709.25 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 474.18 709.25 Td (the ) Tj ET Q q 0 0 0 rg BT 488.53 709.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 518.43 709.25 Td (court ) Tj ET Q q 0 0 0 rg BT 541.11 709.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 564.35 709.25 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 697.25 Td (pretrial ) Tj ET Q q 0 0 0 rg BT 66.94 697.25 Td (purposes ) Tj ET Q q 0 0 0 rg BT 104.55 697.25 Td (in ) Tj ET Q q 0 0 0 rg BT 114.39 697.25 Td (the ) Tj ET Q q 0 0 0 rg BT 128.67 697.25 Td (United ) Tj ET Q q 0 0 0 rg BT 157.95 697.25 Td (States ) Tj ET Q q 0 0 0 rg BT 183.90 697.25 Td (District ) Tj ET Q q 0 0 0 rg BT 215.96 697.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 240.80 697.25 Td (for ) Tj ET Q q 0 0 0 rg BT 254.52 697.25 Td (the ) Tj ET Q q 0 0 0 rg BT 268.80 697.25 Td (Northern ) Tj ET Q q 0 0 0 rg BT 306.96 697.25 Td (District ) Tj ET Q q 0 0 0 rg BT 339.02 697.25 Td (of ) Tj ET Q q 0 0 0 rg BT 349.42 697.25 Td (Florida. ) Tj ET Q q 0 0 0 rg BT 382.72 697.25 Td (The ) Tj ET Q q 0 0 0 rg BT 400.33 697.25 Td (first ) Tj ET Q q 0 0 0 rg BT 418.50 697.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 440.35 697.25 Td ( ) Tj ET Q q 0 0 0 rg BT 442.41 697.25 Td (trial ) Tj ET Q q 0 0 0 rg BT 460.58 697.25 Td (is ) Tj ET Q q 0 0 0 rg BT 469.31 697.25 Td (currently ) Tj ET Q q 0 0 0 rg BT 507.47 697.25 Td (scheduled ) Tj ET Q q 0 0 0 rg BT 549.52 697.25 Td (to ) Tj ET Q q 0 0 0 rg BT 559.36 697.25 Td (take ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 685.25 Td (place ) Tj ET Q q 0 0 0 rg BT 59.59 685.25 Td (in ) Tj ET Q q 0 0 0 rg BT 69.87 685.25 Td (June ) Tj ET Q q 0 0 0 rg BT 90.70 685.25 Td (2018.) Tj ET Q BT /F4 10.00 Tf ET q 0 0 0 rg BT 36.00 669.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 653.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.00 653.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 95.35 653.25 Td (and ) Tj ET Q q 0 0 0 rg BT 112.24 653.25 Td (Pfizer ) Tj ET Q q 0 0 0 rg BT 138.57 653.25 Td (are ) Tj ET Q q 0 0 0 rg BT 153.24 653.25 Td (co-defendants ) Tj ET Q q 0 0 0 rg BT 211.78 653.25 Td (in ) Tj ET Q q 0 0 0 rg BT 222.01 653.25 Td (product ) Tj ET Q q 0 0 0 rg BT 255.01 653.25 Td (liability ) Tj ET Q q 0 0 0 rg BT 288.58 653.25 Td (litigation ) Tj ET Q q 0 0 0 rg BT 327.14 653.25 Td (related ) Tj ET Q q 0 0 0 rg BT 356.80 653.25 Td (to ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 367.04 653.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 395.37 653.25 Td (. ) Tj ET Q q 0 0 0 rg BT 400.33 653.25 Td (Plaintif) Tj ET Q q 0 0 0 rg BT 429.59 653.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 439.27 653.25 Td (assert ) Tj ET Q q 0 0 0 rg BT 464.49 653.25 Td (claims, ) Tj ET Q q 0 0 0 rg BT 495.55 653.25 Td (including ) Tj ET Q q 0 0 0 rg BT 535.78 653.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 564.34 653.25 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 641.25 Td (wrongful ) Tj ET Q q 0 0 0 rg BT 75.62 641.25 Td (death, ) Tj ET Q q 0 0 0 rg BT 102.73 641.25 Td (as ) Tj ET Q q 0 0 0 rg BT 114.01 641.25 Td (a ) Tj ET Q q 0 0 0 rg BT 121.41 641.25 Td (result ) Tj ET Q q 0 0 0 rg BT 146.58 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 157.86 641.25 Td (bleeding ) Tj ET Q q 0 0 0 rg BT 195.25 641.25 Td (they ) Tj ET Q q 0 0 0 rg BT 215.43 641.25 Td (allege ) Tj ET Q q 0 0 0 rg BT 242.25 641.25 Td (was ) Tj ET Q q 0 0 0 rg BT 260.76 641.25 Td (caused ) Tj ET Q q 0 0 0 rg BT 290.92 641.25 Td (by ) Tj ET Q q 0 0 0 rg BT 303.88 641.25 Td (their ) Tj ET Q q 0 0 0 rg BT 325.16 641.25 Td (use ) Tj ET Q q 0 0 0 rg BT 341.45 641.25 Td (of ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 352.73 641.25 Td (Eliquis) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.07 641.25 Td (. ) Tj ET Q q 0 0 0 rg BT 386.31 641.25 Td (The ) Tj ET Q q 0 0 0 rg BT 404.81 641.25 Td (majority ) Tj ET Q q 0 0 0 rg BT 441.65 641.25 Td (of ) Tj ET Q q 0 0 0 rg BT 452.93 641.25 Td (these ) Tj ET Q q 0 0 0 rg BT 476.44 641.25 Td (claims ) Tj ET Q q 0 0 0 rg BT 505.49 641.25 Td (are ) Tj ET Q q 0 0 0 rg BT 520.66 641.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 555.83 641.25 Td (in ) Tj ET Q q 0 0 0 rg BT 566.56 641.25 Td (an ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 629.25 Td (MDL) Tj ET Q q 0 0 0 rg BT 57.85 629.25 Td ( ) Tj ET Q q 0 0 0 rg BT 60.17 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 70.27 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 84.81 629.25 Td (United ) Tj ET Q q 0 0 0 rg BT 114.35 629.25 Td (States ) Tj ET Q q 0 0 0 rg BT 140.55 629.25 Td (District ) Tj ET Q q 0 0 0 rg BT 172.87 629.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 197.97 629.25 Td (for ) Tj ET Q q 0 0 0 rg BT 211.95 629.25 Td (the ) Tj ET Q q 0 0 0 rg BT 226.49 629.25 Td (Southern ) Tj ET Q q 0 0 0 rg BT 264.92 629.25 Td (District ) Tj ET Q q 0 0 0 rg BT 297.23 629.25 Td (of ) Tj ET Q q 0 0 0 rg BT 307.88 629.25 Td (New ) Tj ET Q q 0 0 0 rg BT 328.74 629.25 Td (Y) Tj ET Q q 0 0 0 rg BT 334.96 629.25 Td (ork ) Tj ET Q q 0 0 0 rg BT 350.61 629.25 Td (and ) Tj ET Q q 0 0 0 rg BT 367.37 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 377.47 629.25 Td (state ) Tj ET Q q 0 0 0 rg BT 398.12 629.25 Td (court ) Tj ET Q q 0 0 0 rg BT 420.98 629.25 Td (in ) Tj ET Q q 0 0 0 rg BT 431.08 629.25 Td (Delaware. ) Tj ET Q q 0 0 0 rg BT 473.70 629.25 Td (As ) Tj ET Q q 0 0 0 rg BT 487.13 629.25 Td (of ) Tj ET Q q 0 0 0 rg BT 497.78 629.25 Td (January ) Tj ET Q q 0 0 0 rg BT 531.20 629.25 Td (2018, ) Tj ET Q q 0 0 0 rg BT 556.02 629.25 Td (there ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 617.25 Td (are ) Tj ET Q q 0 0 0 rg BT 50.33 617.25 Td (over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 70.22 617.25 Td (160) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 85.22 617.25 Td ( ) Tj ET Q q 0 0 0 rg BT 87.34 617.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 110.56 617.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 144.89 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 154.79 617.25 Td (courts ) Tj ET Q q 0 0 0 rg BT 181.35 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 191.25 617.25 Td (the ) Tj ET Q q 0 0 0 rg BT 205.59 617.25 Td (United ) Tj ET Q q 0 0 0 rg BT 234.93 617.25 Td (States ) Tj ET Q q 0 0 0 rg BT 260.93 617.25 Td (and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 277.49 617.25 Td (one) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 291.93 617.25 Td ( ) Tj ET Q q 0 0 0 rg BT 294.05 617.25 Td (pending ) Tj ET Q q 0 0 0 rg BT 328.39 617.25 Td (in ) Tj ET Q q 0 0 0 rg BT 338.29 617.25 Td (Canada. ) Tj ET Q q 0 0 0 rg BT 372.89 617.25 Td (Over ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 395.00 617.25 Td (150) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 410.00 617.25 Td ( ) Tj ET Q q 0 0 0 rg BT 412.13 617.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 435.34 617.25 Td (have ) Tj ET Q q 0 0 0 rg BT 456.34 617.25 Td (been ) Tj ET Q q 0 0 0 rg BT 477.34 617.25 Td (dismissed ) Tj ET Q q 0 0 0 rg BT 518.91 617.25 Td (with ) Tj ET Q q 0 0 0 rg BT 538.81 617.25 Td (prejudice ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 605.25 Td (by ) Tj ET Q q 0 0 0 rg BT 48.50 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 63.22 605.25 Td (MDL. ) Tj ET Q q 0 0 0 rg BT 90.44 605.25 Td (Plaintif) Tj ET Q q 0 0 0 rg BT 119.70 605.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 129.42 605.25 Td (have ) Tj ET Q q 0 0 0 rg BT 150.80 605.25 Td (appealed ) Tj ET Q q 0 0 0 rg BT 188.83 605.25 Td (some ) Tj ET Q q 0 0 0 rg BT 212.44 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 223.27 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 237.99 605.25 Td (dismissed ) Tj ET Q q 0 0 0 rg BT 279.94 605.25 Td (cases ) Tj ET Q q 0 0 0 rg BT 303.53 605.25 Td (to ) Tj ET Q q 0 0 0 rg BT 313.81 605.25 Td (the ) Tj ET Q q 0 0 0 rg BT 328.53 605.25 Td (Second ) Tj ET Q q 0 0 0 rg BT 360.47 605.25 Td (Circuit ) Tj ET Q q 0 0 0 rg BT 390.74 605.25 Td (Court ) Tj ET Q q 0 0 0 rg BT 416.02 605.25 Td (of ) Tj ET Q q 0 0 0 rg BT 426.30 605.25 Td (Appeals.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 584.25 Td (SHAREHOLDER ) Tj ET Q q 0 0 0 rg BT 116.29 584.25 Td (DERIV) Tj ET Q q 0 0 0 rg BT 147.23 584.25 Td (A) Tj ET Q q 0 0 0 rg BT 153.71 584.25 Td (TIVE ) Tj ET Q q 0 0 0 rg BT 180.66 584.25 Td (LITIGA) Tj ET Q q 0 0 0 rg BT 216.04 584.25 Td (TION) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 568.25 Td (Since ) Tj ET Q q 0 0 0 rg BT 60.78 568.25 Td (December ) Tj ET Q q 0 0 0 rg BT 104.43 568.25 Td (2015, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 129.50 568.25 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 149.48 568.25 Td ( ) Tj ET Q q 0 0 0 rg BT 152.05 568.25 Td (shareholder ) Tj ET Q q 0 0 0 rg BT 201.26 568.25 Td (derivative ) Tj ET Q q 0 0 0 rg BT 243.80 568.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 279.15 568.25 Td (were ) Tj ET Q q 0 0 0 rg BT 301.14 568.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 322.03 568.25 Td (in ) Tj ET Q q 0 0 0 rg BT 332.37 568.25 Td (New ) Tj ET Q q 0 0 0 rg BT 353.44 568.25 Td (Y) Tj ET Q q 0 0 0 rg BT 359.66 568.25 Td (ork ) Tj ET Q q 0 0 0 rg BT 375.55 568.25 Td (state ) Tj ET Q q 0 0 0 rg BT 396.44 568.25 Td (court ) Tj ET Q q 0 0 0 rg BT 419.56 568.25 Td (against ) Tj ET Q q 0 0 0 rg BT 450.45 568.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 480.21 568.25 Td (of) Tj ET Q q 0 0 0 rg BT 488.36 568.25 Td (ficers ) Tj ET Q q 0 0 0 rg BT 513.13 568.25 Td (and ) Tj ET Q q 0 0 0 rg BT 530.14 568.25 Td (directors ) Tj ET Q q 0 0 0 rg BT 567.69 568.25 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 556.25 Td (the ) Tj ET Q q 0 0 0 rg BT 51.47 556.25 Td (Company) Tj ET Q q 0 0 0 rg BT 89.71 556.25 Td (. ) Tj ET Q q 0 0 0 rg BT 95.22 556.25 Td (The ) Tj ET Q q 0 0 0 rg BT 114.02 556.25 Td (plaintif) Tj ET Q q 0 0 0 rg BT 142.72 556.25 Td (fs ) Tj ET Q q 0 0 0 rg BT 153.19 556.25 Td (allege, ) Tj ET Q q 0 0 0 rg BT 182.82 556.25 Td (among ) Tj ET Q q 0 0 0 rg BT 213.28 556.25 Td (other ) Tj ET Q q 0 0 0 rg BT 237.08 556.25 Td (things, ) Tj ET Q q 0 0 0 rg BT 267.28 556.25 Td (breaches ) Tj ET Q q 0 0 0 rg BT 305.51 556.25 Td (of ) Tj ET Q q 0 0 0 rg BT 317.09 556.25 Td (fiduciary ) Tj ET Q q 0 0 0 rg BT 356.43 556.25 Td (duty ) Tj ET Q q 0 0 0 rg BT 377.46 556.25 Td (surrounding ) Tj ET Q q 0 0 0 rg BT 429.04 556.25 Td (the ) Tj ET Q q 0 0 0 rg BT 444.51 556.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 486.18 556.25 Td (s ) Tj ET Q q 0 0 0 rg BT 493.32 556.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 538.79 556.25 Td (disclosed ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 544.25 Td (October ) Tj ET Q q 0 0 0 rg BT 70.12 544.25 Td (2015 ) Tj ET Q q 0 0 0 rg BT 92.03 544.25 Td (civil ) Tj ET Q q 0 0 0 rg BT 111.72 544.25 Td (settlement ) Tj ET Q q 0 0 0 rg BT 154.73 544.25 Td (with ) Tj ET Q q 0 0 0 rg BT 174.42 544.25 Td (the ) Tj ET Q q 0 0 0 rg BT 188.55 544.25 Td (Securities ) Tj ET Q q 0 0 0 rg BT 229.90 544.25 Td (and ) Tj ET Q q 0 0 0 rg BT 246.25 544.25 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 287.59 544.25 Td (Commission ) Tj ET Q q 0 0 0 rg BT 340.07 544.25 Td (of ) Tj ET Q q 0 0 0 rg BT 350.31 544.25 Td (alleged ) Tj ET Q q 0 0 0 rg BT 381.10 544.25 Td (Foreign ) Tj ET Q q 0 0 0 rg BT 414.12 544.25 Td (Corrupt ) Tj ET Q q 0 0 0 rg BT 447.14 544.25 Td (Practices ) Tj ET Q q 0 0 0 rg BT 484.72 544.25 Td (Act ) Tj ET Q q 0 0 0 rg BT 501.07 544.25 Td (violations ) Tj ET Q q 0 0 0 rg BT 542.43 544.25 Td (in ) Tj ET Q q 0 0 0 rg BT 552.12 544.25 Td (China ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 532.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.07 532.25 Td (which ) Tj ET Q q 0 0 0 rg BT 72.80 532.25 Td (the ) Tj ET Q q 0 0 0 rg BT 87.31 532.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 128.49 532.25 Td (agreed ) Tj ET Q q 0 0 0 rg BT 157.42 532.25 Td (to ) Tj ET Q q 0 0 0 rg BT 167.49 532.25 Td (a ) Tj ET Q q 0 0 0 rg BT 174.22 532.25 Td (payment ) Tj ET Q q 0 0 0 rg BT 210.95 532.25 Td (of ) Tj ET Q q 0 0 0 rg BT 221.57 532.25 Td (approximately ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 281.62 532.25 Td ($14.7 ) Tj ET Q q 0 0 0 rg BT 306.41 532.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.30 532.25 Td ( ) Tj ET Q q 0 0 0 rg BT 337.59 532.25 Td (in ) Tj ET Q q 0 0 0 rg BT 347.66 532.25 Td (disgor) Tj ET Q q 0 0 0 rg BT 372.48 532.25 Td (gement, ) Tj ET Q q 0 0 0 rg BT 406.71 532.25 Td (penalties ) Tj ET Q q 0 0 0 rg BT 444.54 532.25 Td (and ) Tj ET Q q 0 0 0 rg BT 461.27 532.25 Td (interest. ) Tj ET Q q 0 0 0 rg BT 494.99 532.25 Td (As ) Tj ET Q q 0 0 0 rg BT 508.40 532.25 Td (of ) Tj ET Q q 0 0 0 rg BT 519.02 532.25 Td (October ) Tj ET Q q 0 0 0 rg BT 553.52 532.25 Td (2017, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 520.25 Td (all ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 48.50 520.25 Td (three) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 68.48 520.25 Td ( ) Tj ET Q q 0 0 0 rg BT 70.98 520.25 Td (of ) Tj ET Q q 0 0 0 rg BT 81.81 520.25 Td (the ) Tj ET Q q 0 0 0 rg BT 96.53 520.25 Td (lawsuits ) Tj ET Q q 0 0 0 rg BT 131.81 520.25 Td (have ) Tj ET Q q 0 0 0 rg BT 153.18 520.25 Td (been ) Tj ET Q q 0 0 0 rg BT 174.56 520.25 Td (dismissed. ) Tj ET Q q 0 0 0 rg BT 218.83 520.25 Td (The ) Tj ET Q q 0 0 0 rg BT 236.87 520.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 278.26 520.25 Td (received ) Tj ET Q q 0 0 0 rg BT 314.62 520.25 Td (a ) Tj ET Q q 0 0 0 rg BT 321.56 520.25 Td (notice ) Tj ET Q q 0 0 0 rg BT 348.50 520.25 Td (of ) Tj ET Q q 0 0 0 rg BT 359.33 520.25 Td (appeal ) Tj ET Q q 0 0 0 rg BT 387.92 520.25 Td (as ) Tj ET Q q 0 0 0 rg BT 398.75 520.25 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 409.03 520.25 Td (one) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 423.47 520.25 Td ( ) Tj ET Q q 0 0 0 rg BT 425.97 520.25 Td (of ) Tj ET Q q 0 0 0 rg BT 436.80 520.25 Td (the ) Tj ET Q q 0 0 0 rg BT 451.51 520.25 Td (dismissed ) Tj ET Q q 0 0 0 rg BT 493.46 520.25 Td (lawsuits.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 499.25 Td (SECURITIES ) Tj ET Q q 0 0 0 rg BT 99.08 499.25 Td (LITIGA) Tj ET Q q 0 0 0 rg BT 134.46 499.25 Td (TION) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 483.25 Td (In ) Tj ET Q q 0 0 0 rg BT 47.08 483.25 Td (February ) Tj ET Q q 0 0 0 rg BT 85.93 483.25 Td (2018, ) Tj ET Q q 0 0 0 rg BT 111.18 483.25 Td (the ) Tj ET Q q 0 0 0 rg BT 126.15 483.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 167.79 483.25 Td (became ) Tj ET Q q 0 0 0 rg BT 201.07 483.25 Td (aware ) Tj ET Q q 0 0 0 rg BT 227.69 483.25 Td (of ) Tj ET Q q 0 0 0 rg BT 238.77 483.25 Td (a ) Tj ET Q q 0 0 0 rg BT 245.96 483.25 Td (putative ) Tj ET Q q 0 0 0 rg BT 280.93 483.25 Td (class ) Tj ET Q q 0 0 0 rg BT 303.12 483.25 Td (action ) Tj ET Q q 0 0 0 rg BT 330.30 483.25 Td (complaint, ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 375.29 483.25 Td (Joseph ) Tj ET Q q 0 0 0 rg BT 405.81 483.25 Td (Giugno ) Tj ET Q q 0 0 0 rg BT 438.56 483.25 Td (v) Tj ET Q q 0 0 0 rg BT 442.26 483.25 Td (. ) Tj ET Q q 0 0 0 rg BT 447.51 483.25 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 505.81 483.25 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 536.34 483.25 Td (Co., ) Tj ET Q q 0 0 0 rg BT 555.76 483.25 Td (et ) Tj ET Q q 0 0 0 rg BT 565.73 483.25 Td (al.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 471.25 Td (that ) Tj ET Q q 0 0 0 rg BT 53.62 471.25 Td (was ) Tj ET Q q 0 0 0 rg BT 71.80 471.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 92.75 471.25 Td (in ) Tj ET Q q 0 0 0 rg BT 103.15 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 117.99 471.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 138.40 471.25 Td (District ) Tj ET Q q 0 0 0 rg BT 171.02 471.25 Td (for ) Tj ET Q q 0 0 0 rg BT 185.30 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 200.14 471.25 Td (Northern ) Tj ET Q q 0 0 0 rg BT 238.87 471.25 Td (District ) Tj ET Q q 0 0 0 rg BT 271.49 471.25 Td (of ) Tj ET Q q 0 0 0 rg BT 282.44 471.25 Td (California ) Tj ET Q q 0 0 0 rg BT 325.61 471.25 Td (against ) Tj ET Q q 0 0 0 rg BT 356.56 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 371.40 471.25 Td (Company) Tj ET Q q 0 0 0 rg BT 409.64 471.25 Td (, ) Tj ET Q q 0 0 0 rg BT 414.76 471.25 Td (the ) Tj ET Q q 0 0 0 rg BT 429.60 471.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 471.27 471.25 Td (s ) Tj ET Q q 0 0 0 rg BT 477.78 471.25 Td (Chief ) Tj ET Q q 0 0 0 rg BT 502.62 471.25 Td (Executive ) Tj ET Q q 0 0 0 rg BT 545.23 471.25 Td (Of) Tj ET Q q 0 0 0 rg BT 555.60 471.25 Td (ficer) Tj ET Q q 0 0 0 rg BT 573.51 471.25 Td (, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 459.25 Td (Giovanni ) Tj ET Q q 0 0 0 rg BT 77.52 459.25 Td (Caforio, ) Tj ET Q q 0 0 0 rg BT 114.86 459.25 Td (the ) Tj ET Q q 0 0 0 rg BT 131.38 459.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 173.04 459.25 Td (s ) Tj ET Q q 0 0 0 rg BT 181.23 459.25 Td (Chief ) Tj ET Q q 0 0 0 rg BT 207.75 459.25 Td (Financial ) Tj ET Q q 0 0 0 rg BT 249.26 459.25 Td (Of) Tj ET Q q 0 0 0 rg BT 259.63 459.25 Td (ficer) Tj ET Q q 0 0 0 rg BT 277.55 459.25 Td (, ) Tj ET Q q 0 0 0 rg BT 284.35 459.25 Td (Charles ) Tj ET Q q 0 0 0 rg BT 318.24 459.25 Td (A. ) Tj ET Q q 0 0 0 rg BT 332.27 459.25 Td (Bancroft ) Tj ET Q q 0 0 0 rg BT 371.55 459.25 Td (and ) Tj ET Q q 0 0 0 rg BT 390.29 459.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 421.79 459.25 Td (former ) Tj ET Q q 0 0 0 rg BT 453.30 459.25 Td (and ) Tj ET Q q 0 0 0 rg BT 472.03 459.25 Td (current ) Tj ET Q q 0 0 0 rg BT 504.65 459.25 Td (executives ) Tj ET Q q 0 0 0 rg BT 551.15 459.25 Td (of ) Tj ET Q q 0 0 0 rg BT 563.78 459.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 447.25 Td (Company) Tj ET Q q 0 0 0 rg BT 74.24 447.25 Td (. ) Tj ET Q q 0 0 0 rg BT 79.06 447.25 Td (The ) Tj ET Q q 0 0 0 rg BT 96.88 447.25 Td (complaint ) Tj ET Q q 0 0 0 rg BT 139.15 447.25 Td (alleges ) Tj ET Q q 0 0 0 rg BT 169.20 447.25 Td (violations ) Tj ET Q q 0 0 0 rg BT 210.92 447.25 Td (of ) Tj ET Q q 0 0 0 rg BT 221.53 447.25 Td (securities ) Tj ET Q q 0 0 0 rg BT 261.58 447.25 Td (laws ) Tj ET Q q 0 0 0 rg BT 282.19 447.25 Td (for ) Tj ET Q q 0 0 0 rg BT 296.13 447.25 Td (the ) Tj ET Q q 0 0 0 rg BT 310.62 447.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 352.29 447.25 Td (s ) Tj ET Q q 0 0 0 rg BT 358.46 447.25 Td (disclosures ) Tj ET Q q 0 0 0 rg BT 405.18 447.25 Td (related ) Tj ET Q q 0 0 0 rg BT 434.66 447.25 Td (to ) Tj ET Q q 0 0 0 rg BT 444.72 447.25 Td (the ) Tj ET Q q 0 0 0 rg BT 459.22 447.25 Td (CheckMate ) Tj ET Q q 0 0 0 rg BT 507.59 447.25 Td (-026 ) Tj ET Q q 0 0 0 rg BT 528.20 447.25 Td (clinical ) Tj ET Q q 0 0 0 rg BT 559.91 447.25 Td (trial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 435.25 Td (in ) Tj ET Q q 0 0 0 rg BT 46.28 435.25 Td (lung ) Tj ET Q q 0 0 0 rg BT 66.56 435.25 Td (cancer) Tj ET Q q 0 0 0 rg BT 92.09 435.25 Td (. ) Tj ET Q q 0 0 0 rg BT 96.91 435.25 Td (The ) Tj ET Q q 0 0 0 rg BT 114.96 435.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 156.34 435.25 Td (intends ) Tj ET Q q 0 0 0 rg BT 187.73 435.25 Td (to ) Tj ET Q q 0 0 0 rg BT 198.01 435.25 Td (defend ) Tj ET Q q 0 0 0 rg BT 227.71 435.25 Td (itself ) Tj ET Q q 0 0 0 rg BT 250.21 435.25 Td (vigorously ) Tj ET Q q 0 0 0 rg BT 295.49 435.25 Td (in ) Tj ET Q q 0 0 0 rg BT 305.77 435.25 Td (this ) Tj ET Q q 0 0 0 rg BT 322.71 435.25 Td (litigation.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 414.25 Td (GOVERNMENT) Tj ET Q q 0 0 0 rg BT 109.71 414.25 Td ( ) Tj ET Q q 0 0 0 rg BT 112.21 414.25 Td (INVESTIGA) Tj ET Q q 0 0 0 rg BT 167.60 414.25 Td (TIONS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 398.25 Td (Like ) Tj ET Q q 0 0 0 rg BT 56.96 398.25 Td (other ) Tj ET Q q 0 0 0 rg BT 80.14 398.25 Td (pharmaceutical ) Tj ET Q q 0 0 0 rg BT 143.85 398.25 Td (companies, ) Tj ET Q q 0 0 0 rg BT 191.74 398.25 Td (the ) Tj ET Q q 0 0 0 rg BT 206.59 398.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 248.11 398.25 Td (and ) Tj ET Q q 0 0 0 rg BT 265.19 398.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 295.02 398.25 Td (of ) Tj ET Q q 0 0 0 rg BT 305.98 398.25 Td (its ) Tj ET Q q 0 0 0 rg BT 318.07 398.25 Td (subsidiaries ) Tj ET Q q 0 0 0 rg BT 367.92 398.25 Td (are ) Tj ET Q q 0 0 0 rg BT 382.76 398.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 413.71 398.25 Td (to ) Tj ET Q q 0 0 0 rg BT 424.13 398.25 Td (extensive ) Tj ET Q q 0 0 0 rg BT 464.52 398.25 Td (regulation ) Tj ET Q q 0 0 0 rg BT 507.70 398.25 Td (by ) Tj ET Q q 0 0 0 rg BT 520.33 398.25 Td (national, ) Tj ET Q q 0 0 0 rg BT 557.68 398.25 Td (state ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 386.25 Td (and ) Tj ET Q q 0 0 0 rg BT 53.08 386.25 Td (local ) Tj ET Q q 0 0 0 rg BT 75.16 386.25 Td (government ) Tj ET Q q 0 0 0 rg BT 125.57 386.25 Td (agencies ) Tj ET Q q 0 0 0 rg BT 162.64 386.25 Td (in ) Tj ET Q q 0 0 0 rg BT 173.06 386.25 Td (the ) Tj ET Q q 0 0 0 rg BT 187.92 386.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 208.35 386.25 Td (and ) Tj ET Q q 0 0 0 rg BT 225.43 386.25 Td (other ) Tj ET Q q 0 0 0 rg BT 248.62 386.25 Td (countries ) Tj ET Q q 0 0 0 rg BT 287.92 386.25 Td (in ) Tj ET Q q 0 0 0 rg BT 298.34 386.25 Td (which ) Tj ET Q q 0 0 0 rg BT 325.42 386.25 Td (BMS ) Tj ET Q q 0 0 0 rg BT 349.19 386.25 Td (operates. ) Tj ET Q q 0 0 0 rg BT 387.07 386.25 Td (As ) Tj ET Q q 0 0 0 rg BT 400.82 386.25 Td (a ) Tj ET Q q 0 0 0 rg BT 407.91 386.25 Td (result, ) Tj ET Q q 0 0 0 rg BT 435.27 386.25 Td (the ) Tj ET Q q 0 0 0 rg BT 450.13 386.25 Td (Company) Tj ET Q q 0 0 0 rg BT 488.37 386.25 Td (, ) Tj ET Q q 0 0 0 rg BT 493.51 386.25 Td (from ) Tj ET Q q 0 0 0 rg BT 515.59 386.25 Td (time ) Tj ET Q q 0 0 0 rg BT 536.01 386.25 Td (to ) Tj ET Q q 0 0 0 rg BT 546.43 386.25 Td (time, ) Tj ET Q q 0 0 0 rg BT 569.35 386.25 Td (is ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 374.25 Td (subject ) Tj ET Q q 0 0 0 rg BT 66.78 374.25 Td (to ) Tj ET Q q 0 0 0 rg BT 77.01 374.25 Td (various ) Tj ET Q q 0 0 0 rg BT 108.90 374.25 Td (governmental ) Tj ET Q q 0 0 0 rg BT 166.33 374.25 Td (inquiries ) Tj ET Q q 0 0 0 rg BT 203.78 374.25 Td (and ) Tj ET Q q 0 0 0 rg BT 220.67 374.25 Td (investigations. ) Tj ET Q q 0 0 0 rg BT 281.18 374.25 Td (It ) Tj ET Q q 0 0 0 rg BT 289.74 374.25 Td (is ) Tj ET Q q 0 0 0 rg BT 298.86 374.25 Td (possible ) Tj ET Q q 0 0 0 rg BT 334.09 374.25 Td (that ) Tj ET Q q 0 0 0 rg BT 351.54 374.25 Td (criminal ) Tj ET Q q 0 0 0 rg BT 387.31 374.25 Td (char) Tj ET Q q 0 0 0 rg BT 404.34 374.25 Td (ges, ) Tj ET Q q 0 0 0 rg BT 422.62 374.25 Td (substantial ) Tj ET Q q 0 0 0 rg BT 467.85 374.25 Td (fines ) Tj ET Q q 0 0 0 rg BT 489.74 374.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 517.74 374.25 Td (civil ) Tj ET Q q 0 0 0 rg BT 537.96 374.25 Td (penalties, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 362.25 Td (could ) Tj ET Q q 0 0 0 rg BT 60.72 362.25 Td (result ) Tj ET Q q 0 0 0 rg BT 85.43 362.25 Td (from ) Tj ET Q q 0 0 0 rg BT 107.37 362.25 Td (government ) Tj ET Q q 0 0 0 rg BT 157.64 362.25 Td (investigations.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 341.25 Td (ENVIRONMENT) Tj ET Q q 0 0 0 rg BT 112.48 341.25 Td (AL) Tj ET Q q 0 0 0 rg BT 125.82 341.25 Td ( PROCEEDINGS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 325.25 Td (As ) Tj ET Q q 0 0 0 rg BT 49.23 325.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 93.56 325.25 Td (reported, ) Tj ET Q q 0 0 0 rg BT 131.49 325.25 Td (the ) Tj ET Q q 0 0 0 rg BT 145.82 325.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 186.82 325.25 Td (is ) Tj ET Q q 0 0 0 rg BT 195.60 325.25 Td (a ) Tj ET Q q 0 0 0 rg BT 202.15 325.25 Td (party ) Tj ET Q q 0 0 0 rg BT 224.81 325.25 Td (to ) Tj ET Q q 0 0 0 rg BT 234.70 325.25 Td (several ) Tj ET Q q 0 0 0 rg BT 265.13 325.25 Td (environmental ) Tj ET Q q 0 0 0 rg BT 325.00 325.25 Td (proceedings ) Tj ET Q q 0 0 0 rg BT 375.43 325.25 Td (and ) Tj ET Q q 0 0 0 rg BT 391.98 325.25 Td (other ) Tj ET Q q 0 0 0 rg BT 414.64 325.25 Td (matters, ) Tj ET Q q 0 0 0 rg BT 448.69 325.25 Td (and ) Tj ET Q q 0 0 0 rg BT 465.24 325.25 Td (is ) Tj ET Q q 0 0 0 rg BT 474.03 325.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 521.69 325.25 Td (under ) Tj ET Q q 0 0 0 rg BT 546.57 325.25 Td (various ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 313.25 Td (state, ) Tj ET Q q 0 0 0 rg BT 59.56 313.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 90.05 313.25 Td (and ) Tj ET Q q 0 0 0 rg BT 107.23 313.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 138.84 313.25 Td (laws, ) Tj ET Q q 0 0 0 rg BT 162.40 313.25 Td (including ) Tj ET Q q 0 0 0 rg BT 202.91 313.25 Td (CERCLA, ) Tj ET Q q 0 0 0 rg BT 247.60 313.25 Td (for ) Tj ET Q q 0 0 0 rg BT 261.99 313.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 291.93 313.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 314.67 313.25 Td (of ) Tj ET Q q 0 0 0 rg BT 325.73 313.25 Td (investigating ) Tj ET Q q 0 0 0 rg BT 380.13 313.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 408.41 313.25 Td (remediating ) Tj ET Q q 0 0 0 rg BT 458.91 313.25 Td (contamination ) Tj ET Q q 0 0 0 rg BT 518.85 313.25 Td (resulting ) Tj ET Q q 0 0 0 rg BT 556.58 313.25 Td (from ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 301.25 Td (past ) Tj ET Q q 0 0 0 rg BT 54.61 301.25 Td (industrial ) Tj ET Q q 0 0 0 rg BT 94.88 301.25 Td (activity ) Tj ET Q q 0 0 0 rg BT 127.37 301.25 Td (at ) Tj ET Q q 0 0 0 rg BT 137.09 301.25 Td (the ) Tj ET Q q 0 0 0 rg BT 151.81 301.25 Td (Company’) Tj ET Q q 0 0 0 rg BT 193.47 301.25 Td (s ) Tj ET Q q 0 0 0 rg BT 199.86 301.25 Td (current ) Tj ET Q q 0 0 0 rg BT 230.68 301.25 Td (or ) Tj ET Q q 0 0 0 rg BT 241.51 301.25 Td (former ) Tj ET Q q 0 0 0 rg BT 271.21 301.25 Td (sites ) Tj ET Q q 0 0 0 rg BT 291.49 301.25 Td (or ) Tj ET Q q 0 0 0 rg BT 302.32 301.25 Td (at ) Tj ET Q q 0 0 0 rg BT 312.04 301.25 Td (waste ) Tj ET Q q 0 0 0 rg BT 337.31 301.25 Td (disposal ) Tj ET Q q 0 0 0 rg BT 372.59 301.25 Td (or ) Tj ET Q q 0 0 0 rg BT 383.42 301.25 Td (reprocessing ) Tj ET Q q 0 0 0 rg BT 436.45 301.25 Td (facilities ) Tj ET Q q 0 0 0 rg BT 473.38 301.25 Td (operated ) Tj ET Q q 0 0 0 rg BT 510.31 301.25 Td (by ) Tj ET Q q 0 0 0 rg BT 522.81 301.25 Td (third ) Tj ET Q q 0 0 0 rg BT 544.19 301.25 Td (parties.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 280.25 Td (CERCLA) Tj ET Q q 0 0 0 rg BT 77.67 280.25 Td ( Matters) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 264.25 Td (W) Tj ET Q q 0 0 0 rg BT 45.04 264.25 Td (ith ) Tj ET Q q 0 0 0 rg BT 58.78 264.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 90.28 264.25 Td (to ) Tj ET Q q 0 0 0 rg BT 101.25 264.25 Td (CERCLA) Tj ET Q q 0 0 0 rg BT 140.14 264.25 Td ( ) Tj ET Q q 0 0 0 rg BT 143.33 264.25 Td (matters ) Tj ET Q q 0 0 0 rg BT 175.95 264.25 Td (for ) Tj ET Q q 0 0 0 rg BT 190.79 264.25 Td (which ) Tj ET Q q 0 0 0 rg BT 218.42 264.25 Td (the ) Tj ET Q q 0 0 0 rg BT 233.82 264.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 275.90 264.25 Td (is ) Tj ET Q q 0 0 0 rg BT 285.75 264.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 334.48 264.25 Td (under ) Tj ET Q q 0 0 0 rg BT 360.44 264.25 Td (various ) Tj ET Q q 0 0 0 rg BT 393.06 264.25 Td (state, ) Tj ET Q q 0 0 0 rg BT 417.07 264.25 Td (federal ) Tj ET Q q 0 0 0 rg BT 448.01 264.25 Td (and ) Tj ET Q q 0 0 0 rg BT 465.64 264.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 497.70 264.25 Td (laws, ) Tj ET Q q 0 0 0 rg BT 521.72 264.25 Td (the ) Tj ET Q q 0 0 0 rg BT 537.12 264.25 Td (Company ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 252.25 Td (typically ) Tj ET Q q 0 0 0 rg BT 73.73 252.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 113.69 252.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 151.42 252.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 174.17 252.25 Td (based ) Tj ET Q q 0 0 0 rg BT 199.68 252.25 Td (on ) Tj ET Q q 0 0 0 rg BT 212.42 252.25 Td (information ) Tj ET Q q 0 0 0 rg BT 262.38 252.25 Td (obtained ) Tj ET Q q 0 0 0 rg BT 299.55 252.25 Td (from ) Tj ET Q q 0 0 0 rg BT 321.73 252.25 Td (the ) Tj ET Q q 0 0 0 rg BT 336.69 252.25 Td (U.S. ) Tj ET Q q 0 0 0 rg BT 357.22 252.25 Td (Environmental ) Tj ET Q q 0 0 0 rg BT 419.39 252.25 Td (Protection ) Tj ET Q q 0 0 0 rg BT 462.63 252.25 Td (Agency) Tj ET Q q 0 0 0 rg BT 493.08 252.25 Td (, ) Tj ET Q q 0 0 0 rg BT 498.33 252.25 Td (or ) Tj ET Q q 0 0 0 rg BT 509.40 252.25 Td (counterpart ) Tj ET Q q 0 0 0 rg BT 557.67 252.25 Td (state ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 240.25 Td (or ) Tj ET Q q 0 0 0 rg BT 47.16 240.25 Td (foreign ) Tj ET Q q 0 0 0 rg BT 78.87 240.25 Td (agency ) Tj ET Q q 0 0 0 rg BT 110.02 240.25 Td (and/or ) Tj ET Q q 0 0 0 rg BT 138.39 240.25 Td (studies ) Tj ET Q q 0 0 0 rg BT 169.00 240.25 Td (prepared ) Tj ET Q q 0 0 0 rg BT 206.81 240.25 Td (by ) Tj ET Q q 0 0 0 rg BT 219.64 240.25 Td (independent ) Tj ET Q q 0 0 0 rg BT 271.34 240.25 Td (consultants, ) Tj ET Q q 0 0 0 rg BT 321.67 240.25 Td (including ) Tj ET Q q 0 0 0 rg BT 362.27 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 377.32 240.25 Td (total ) Tj ET Q q 0 0 0 rg BT 397.93 240.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 439.08 240.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 461.91 240.25 Td (for ) Tj ET Q q 0 0 0 rg BT 476.40 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 491.45 240.25 Td (site ) Tj ET Q q 0 0 0 rg BT 508.17 240.25 Td (and ) Tj ET Q q 0 0 0 rg BT 525.44 240.25 Td (the ) Tj ET Q q 0 0 0 rg BT 540.48 240.25 Td (expected ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 228.25 Td (cost-sharing, ) Tj ET Q q 0 0 0 rg BT 88.77 228.25 Td (if ) Tj ET Q q 0 0 0 rg BT 96.26 228.25 Td (any) Tj ET Q q 0 0 0 rg BT 110.05 228.25 Td (, ) Tj ET Q q 0 0 0 rg BT 113.94 228.25 Td (with ) Tj ET Q q 0 0 0 rg BT 133.11 228.25 Td (other ) Tj ET Q q 0 0 0 rg BT 155.05 228.25 Td (“potentially ) Tj ET Q q 0 0 0 rg BT 203.64 228.25 Td (responsible ) Tj ET Q q 0 0 0 rg BT 250.58 228.25 Td (parties,” ) Tj ET Q q 0 0 0 rg BT 285.56 228.25 Td (and ) Tj ET Q q 0 0 0 rg BT 301.39 228.25 Td (the ) Tj ET Q q 0 0 0 rg BT 314.99 228.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 355.27 228.25 Td (accrues ) Tj ET Q q 0 0 0 rg BT 386.63 228.25 Td (liabilities ) Tj ET Q q 0 0 0 rg BT 425.24 228.25 Td (when ) Tj ET Q q 0 0 0 rg BT 448.29 228.25 Td (they ) Tj ET Q q 0 0 0 rg BT 466.90 228.25 Td (are ) Tj ET Q q 0 0 0 rg BT 480.49 228.25 Td (probable ) Tj ET Q q 0 0 0 rg BT 516.87 228.25 Td (and ) Tj ET Q q 0 0 0 rg BT 532.69 228.25 Td (reasonably ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 216.25 Td (estimable. ) Tj ET Q q 0 0 0 rg BT 79.35 216.25 Td (The ) Tj ET Q q 0 0 0 rg BT 97.62 216.25 Td (Company ) Tj ET Q q 0 0 0 rg BT 139.23 216.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 180.28 216.25 Td (its ) Tj ET Q q 0 0 0 rg BT 192.46 216.25 Td (share ) Tj ET Q q 0 0 0 rg BT 216.28 216.25 Td (of ) Tj ET Q q 0 0 0 rg BT 227.34 216.25 Td (future ) Tj ET Q q 0 0 0 rg BT 253.94 216.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 276.67 216.25 Td (for ) Tj ET Q q 0 0 0 rg BT 291.05 216.25 Td (these ) Tj ET Q q 0 0 0 rg BT 314.32 216.25 Td (sites ) Tj ET Q q 0 0 0 rg BT 334.83 216.25 Td (to ) Tj ET Q q 0 0 0 rg BT 345.33 216.25 Td (be ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.50 216.25 Td ($62.8 ) Tj ET Q q 0 0 0 rg BT 382.72 216.25 Td (million) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 411.62 216.25 Td ( ) Tj ET Q q 0 0 0 rg BT 414.34 216.25 Td (at ) Tj ET Q q 0 0 0 rg BT 424.28 216.25 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 483.09 216.25 Td (2017, ) Tj ET Q q 0 0 0 rg BT 508.32 216.25 Td (which ) Tj ET Q q 0 0 0 rg BT 535.49 216.25 Td (represents ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 204.25 Td (the ) Tj ET Q q 0 0 0 rg BT 50.69 204.25 Td (sum ) Tj ET Q q 0 0 0 rg BT 69.84 204.25 Td (of ) Tj ET Q q 0 0 0 rg BT 80.64 204.25 Td (best ) Tj ET Q q 0 0 0 rg BT 99.23 204.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 138.92 204.25 Td (or) Tj ET Q q 0 0 0 rg BT 146.84 204.25 Td (, ) Tj ET Q q 0 0 0 rg BT 151.82 204.25 Td (where ) Tj ET Q q 0 0 0 rg BT 178.72 204.25 Td (no ) Tj ET Q q 0 0 0 rg BT 191.20 204.25 Td (best ) Tj ET Q q 0 0 0 rg BT 209.78 204.25 Td (estimate ) Tj ET Q q 0 0 0 rg BT 245.58 204.25 Td (can ) Tj ET Q q 0 0 0 rg BT 261.93 204.25 Td (reasonably ) Tj ET Q q 0 0 0 rg BT 307.72 204.25 Td (be ) Tj ET Q q 0 0 0 rg BT 319.64 204.25 Td (made, ) Tj ET Q q 0 0 0 rg BT 346.27 204.25 Td (estimates ) Tj ET Q q 0 0 0 rg BT 385.96 204.25 Td (of ) Tj ET Q q 0 0 0 rg BT 396.76 204.25 Td (the ) Tj ET Q q 0 0 0 rg BT 411.45 204.25 Td (minimal ) Tj ET Q q 0 0 0 rg BT 447.26 204.25 Td (probable ) Tj ET Q q 0 0 0 rg BT 484.72 204.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 517.19 204.25 Td (among ) Tj ET Q q 0 0 0 rg BT 546.88 204.25 Td (a ) Tj ET Q q 0 0 0 rg BT 553.80 204.25 Td (range ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 192.25 Td (of ) Tj ET Q q 0 0 0 rg BT 46.81 192.25 Td (such ) Tj ET Q q 0 0 0 rg BT 67.61 192.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 90.09 192.25 Td (\(without ) Tj ET Q q 0 0 0 rg BT 126.45 192.25 Td (taking ) Tj ET Q q 0 0 0 rg BT 153.92 192.25 Td (into ) Tj ET Q q 0 0 0 rg BT 171.95 192.25 Td (account ) Tj ET Q q 0 0 0 rg BT 205.52 192.25 Td (any ) Tj ET Q q 0 0 0 rg BT 222.44 192.25 Td (potential ) Tj ET Q q 0 0 0 rg BT 259.90 192.25 Td (recoveries ) Tj ET Q q 0 0 0 rg BT 303.46 192.25 Td (from ) Tj ET Q q 0 0 0 rg BT 325.38 192.25 Td (other ) Tj ET Q q 0 0 0 rg BT 348.40 192.25 Td (parties\). ) Tj ET Q q 0 0 0 rg BT 383.18 192.25 Td (The ) Tj ET Q q 0 0 0 rg BT 401.20 192.25 Td (amount ) Tj ET Q q 0 0 0 rg BT 433.67 192.25 Td (includes ) Tj ET Q q 0 0 0 rg BT 469.47 192.25 Td (the ) Tj ET Q q 0 0 0 rg BT 484.17 192.25 Td (estimated ) Tj ET Q q 0 0 0 rg BT 524.96 192.25 Td (costs ) Tj ET Q q 0 0 0 rg BT 547.44 192.25 Td (for ) Tj ET Q q 0 0 0 rg BT 561.57 192.25 Td (any ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 180.25 Td (additional ) Tj ET Q q 0 0 0 rg BT 78.49 180.25 Td (probable ) Tj ET Q q 0 0 0 rg BT 115.98 180.25 Td (loss ) Tj ET Q q 0 0 0 rg BT 134.04 180.25 Td (associated ) Tj ET Q q 0 0 0 rg BT 177.63 180.25 Td (with ) Tj ET Q q 0 0 0 rg BT 197.91 180.25 Td (the ) Tj ET Q q 0 0 0 rg BT 212.63 180.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 257.34 180.25 Td (disclosed ) Tj ET Q q 0 0 0 rg BT 297.06 180.25 Td (North ) Tj ET Q q 0 0 0 rg BT 322.89 180.25 Td (Brunswick ) Tj ET Q q 0 0 0 rg BT 368.54 180.25 Td (T) Tj ET Q q 0 0 0 rg BT 373.95 180.25 Td (ownship ) Tj ET Q q 0 0 0 rg BT 410.34 180.25 Td (High ) Tj ET Q q 0 0 0 rg BT 432.84 180.25 Td (School ) Tj ET Q q 0 0 0 rg BT 463.12 180.25 Td (Remediation ) Tj ET Q q 0 0 0 rg BT 516.72 180.25 Td (Site.) Tj ET Q endstream endobj 203 0 obj <> endobj 204 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (101) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (Note ) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 58.49 749.25 Td (19) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 68.49 749.25 Td (. SELECTED QUAR) Tj ET Q q 0 0 0 rg BT 158.44 749.25 Td (TERL) Tj ET Q q 0 0 0 rg BT 184.75 749.25 Td (Y) Tj ET Q q 0 0 0 rg BT 191.60 749.25 Td ( FINANCIAL) Tj ET Q q 0 0 0 rg BT 250.22 749.25 Td ( DA) Tj ET Q q 0 0 0 rg BT 266.42 749.25 Td (T) Tj ET Q q 0 0 0 rg BT 272.35 749.25 Td (A) Tj ET Q q 0 0 0 rg BT 279.02 749.25 Td ( \(UNAUDITED\)) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 725.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 725.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 725.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 725.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 725.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 725.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 725.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 699.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 699.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 699.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 699.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 699.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 699.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 699.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 673.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 673.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 673.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 673.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 673.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 673.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 673.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 673.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 673.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 673.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 673.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 647.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 647.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 647.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 647.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 647.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 647.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 647.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 647.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 647.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 647.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 647.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 625.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 625.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 625.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 625.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 625.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 625.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 625.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 625.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 625.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 625.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 625.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 595.75 186.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 595.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 595.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 595.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 595.75 66.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 595.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 595.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 595.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 595.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 595.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 595.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 573.75 186.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 573.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 573.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 573.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 573.75 66.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 573.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 573.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 573.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 573.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 573.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 573.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 551.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 551.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 551.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 551.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 551.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 551.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 551.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 551.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 551.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 551.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 551.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 523.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 523.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 523.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 523.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 523.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 523.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 523.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 523.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 523.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 523.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 523.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 469.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 469.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 469.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 469.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 469.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 469.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 469.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 469.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 469.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 469.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 469.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 443.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 443.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 443.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 443.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 443.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 443.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 443.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 443.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 443.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 443.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 443.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 417.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 417.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 417.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 417.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 417.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 417.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 417.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 417.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 417.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 417.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 417.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 391.75 186.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 391.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 391.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 391.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 391.75 66.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 391.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 391.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 391.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 391.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 391.75 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 391.75 67.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 369.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 369.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 369.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 369.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 369.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 369.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 369.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 369.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 369.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 369.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 369.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 339.75 186.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 339.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 339.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 339.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 339.75 66.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 339.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 339.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 339.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 339.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 339.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 339.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 317.75 186.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 317.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 317.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 317.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 317.75 66.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 317.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 317.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 317.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 317.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 317.75 4.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 317.75 67.00 -9.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 295.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 295.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 295.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 295.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 295.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 295.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 295.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 267.75 186.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 222.50 267.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 226.50 267.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 293.50 267.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 297.50 267.75 66.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 363.50 267.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 367.50 267.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 434.50 267.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 438.50 267.75 67.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 505.50 267.75 4.00 -15.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 509.50 267.75 67.00 -15.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 226.5 725.75 m 293.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 297.5 725.75 m 363.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 725.75 m 434.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 438.5 725.75 m 505.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 509.5 725.75 m 576.5 725.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 226.5 469.75 m 293.5 469.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 297.5 469.75 m 363.5 469.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 367.5 469.75 m 434.5 469.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 438.5 469.75 m 505.5 469.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 509.5 469.75 m 576.5 469.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 730.00 Td (Dollars in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 236.35 729.98 Td (First Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 302.85 729.98 Td (Second Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 375.55 729.98 Td (Third Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.55 729.98 Td (Fourth Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 534.55 729.98 Td (Y) Tj ET Q q 0 0 0 rg BT 539.88 729.98 Td (ear) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 39 714.91259765625 m 59 714.91259765625 l s q 0 0 0 rg BT 39.00 716.48 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 703.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 703.32 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 703.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 703.32 Td (4,929) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 703.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 703.32 Td (5,144) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 703.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 703.32 Td (5,254) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 703.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 703.32 Td (5,449) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 703.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 703.32 Td (20,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 690.32 Td (Gross Mar) Tj ET Q q 0 0 0 rg BT 81.40 690.32 Td (gin) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 690.32 Td (3,670) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 690.32 Td (3,582) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 690.32 Td (3,682) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 690.32 Td (3,776) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 690.32 Td (14,710) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 677.32 Td (Net Earnings/\(Loss\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 677.32 Td (1,526) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.65 677.32 Td (922) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 677.32 Td (856) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.80 677.37 Td (\(2,329) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 677.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 677.32 Td (975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 664.32 Td (Net Earnings/\(Loss\) ) Tj ET Q q 0 0 0 rg BT 122.04 664.32 Td (Attributable to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 651.32 Td (Noncontrolling Interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 276.30 651.32 Td (\(48) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 289.65 651.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.65 651.32 Td (6) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 651.32 Td (1) Tj ET Q q 0 0 0 rg BT 425.65 651.32 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 493.30 651.37 Td (\(1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 651.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 651.32 Td (\(32) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 651.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 638.32 Td (BMS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 638.32 Td (1,574) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 344.65 638.32 Td (916) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 415.65 638.32 Td (845) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 475.80 638.37 Td (\(2,328) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 638.32 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 638.32 Td (1,007) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 615.42 Td (Earnings/\(Loss\) per Share - Basic) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 173.96 619.95 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 615.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 615.42 Td (0.95) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 615.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 615.42 Td (0.56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 615.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 615.42 Td (0.52) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 615.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.80 615.47 Td (\(1.42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 615.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 615.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 615.42 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 600.42 Td (Earnings/\(Loss\) per Share - Diluted) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 181.74 604.95 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 600.42 Td (0.94) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 600.42 Td (0.56) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 600.42 Td (0.51) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 480.80 600.47 Td (\(1.42) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 501.65 600.42 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 600.42 Td (0.61) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 577.32 Td (Cash dividends declared per common share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 577.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 577.32 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 577.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 577.32 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 577.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 577.32 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 577.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.15 577.32 Td (0.40) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 577.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 577.32 Td (1.57) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 555.32 Td (Cash and cash equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 555.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 555.32 Td (3,910) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 555.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 555.32 Td (3,470) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 555.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 555.32 Td (4,644) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 555.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 555.32 Td (5,421) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 555.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 555.32 Td (5,421) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 541.42 Td (Marketable securities) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 124.80 545.95 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 541.42 Td (4,884) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 541.42 Td (5,615) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 541.42 Td (5,004) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 541.42 Td (3,871) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 541.42 Td (3,871) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 527.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 527.32 Td (otal ) Tj ET Q q 0 0 0 rg BT 61.63 527.32 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.15 527.32 Td (32,937) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.15 527.32 Td (33,409) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 527.32 Td (33,977) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.15 527.32 Td (33,551) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 527.32 Td (33,551) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 513.42 Td (Long-term debt) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 101.48 517.95 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 513.42 Td (7,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 513.42 Td (6,91) Tj ET Q q 0 0 0 rg BT 354.65 513.42 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 513.42 Td (6,982) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 513.42 Td (6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 513.42 Td (6,975) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 499.32 Td (Equity) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.15 499.32 Td (14,535) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.15 499.32 Td (14,821) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 499.32 Td (14,914) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.15 499.32 Td (1) Tj ET Q q 0 0 0 rg BT 479.15 499.32 Td (1,847) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 499.32 Td (1) Tj ET Q q 0 0 0 rg BT 550.15 499.32 Td (1,847) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 474.00 Td (Dollars in Millions, except per share data) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 236.35 473.98 Td (First Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 302.85 473.98 Td (Second Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 375.55 473.98 Td (Third Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 444.55 473.98 Td (Fourth Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 534.55 473.98 Td (Y) Tj ET Q q 0 0 0 rg BT 539.44 473.98 Td (ear) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 39 458.91259765625 m 59 458.91259765625 l s q 0 0 0 rg BT 39.00 460.48 Td (2016) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 229.00 461.00 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 300.00 461.00 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 370.00 461.00 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 441.00 461.00 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 512.00 461.00 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 447.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 447.32 Td (otal Revenues) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 447.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 447.32 Td (4,391) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 447.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 447.32 Td (4,871) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 447.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 447.32 Td (4,922) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 447.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 447.32 Td (5,243) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 447.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 447.32 Td (19,427) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 434.32 Td (Gross Mar) Tj ET Q q 0 0 0 rg BT 81.40 434.32 Td (gin) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 434.32 Td (3,339) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 434.32 Td (3,665) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 434.32 Td (3,617) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 434.32 Td (3,860) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 434.32 Td (14,481) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 421.32 Td (Net Earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 421.32 Td (1,206) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 421.32 Td (1,188) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 421.32 Td (1,215) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.65 421.32 Td (898) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 421.32 Td (4,507) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 408.32 Td (Net Earnings ) Tj ET Q q 0 0 0 rg BT 93.71 408.32 Td (Attributable to:) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 395.32 Td (Noncontrolling Interest) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 279.65 395.32 Td (1) Tj ET Q q 0 0 0 rg BT 284.65 395.32 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 349.65 395.32 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 420.65 395.32 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 496.65 395.32 Td (4) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 395.32 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 51.00 382.32 Td (BMS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 382.32 Td (1,195) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 382.32 Td (1,166) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 382.32 Td (1,202) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 486.65 382.32 Td (894) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 382.32 Td (4,457) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 359.42 Td (Earnings per Share - Basic) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 145.63 363.95 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 359.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 359.42 Td (0.72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 359.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 359.42 Td (0.70) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 359.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 359.42 Td (0.72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 359.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.15 359.42 Td (0.53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 359.42 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 359.42 Td (2.67) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 344.42 Td (Earnings per Share - Diluted) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 153.41 348.95 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 344.42 Td (0.71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 344.42 Td (0.69) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 344.42 Td (0.72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.15 344.42 Td (0.53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 344.42 Td (2.65) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 321.32 Td (Cash dividends declared per common share) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 321.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 272.15 321.32 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 321.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 342.15 321.32 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 321.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 413.15 321.32 Td (0.38) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 321.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 484.15 321.32 Td (0.39) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 321.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 555.15 321.32 Td (1.53) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 299.32 Td (Cash and cash equivalents) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 229.00 299.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 299.32 Td (2,644) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 300.00 299.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 299.32 Td (2,934) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 370.00 299.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 299.32 Td (3,432) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 441.00 299.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 299.32 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.00 299.32 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 299.32 Td (4,237) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 285.42 Td (Marketable securities) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 124.80 289.95 Td (\(b\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 285.42 Td (5,352) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 285.42 Td (4,998) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 285.42 Td (5,163) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 285.42 Td (4,832) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 285.42 Td (4,832) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 271.32 Td (T) Tj ET Q q 0 0 0 rg BT 44.76 271.32 Td (otal ) Tj ET Q q 0 0 0 rg BT 61.63 271.32 Td (Assets) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.15 271.32 Td (31,892) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.15 271.32 Td (32,831) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 271.32 Td (33,727) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.15 271.32 Td (33,707) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 271.32 Td (33,707) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 258.32 Td (Long-term debt) Tj ET Q BT /F1 10.00 Tf ET BT /F1 6.50 Tf ET q 0 0 0 rg BT 101.48 262.85 Td (\(c\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 267.15 257.42 Td (6,593) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 337.15 257.42 Td (6,581) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 408.15 257.42 Td (6,585) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 479.15 257.42 Td (6,465) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 257.42 Td (6,465) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 243.32 Td (Equity) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 262.15 243.32 Td (14,551) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 332.15 243.32 Td (15,078) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 403.15 243.32 Td (15,781) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.15 243.32 Td (16,347) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 545.15 243.32 Td (16,347) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 221.70 Td (\(a\)) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 56.00 221.70 Td (Earnings per share for the quarters may not add to the amounts for the year) Tj ET Q q 0 0 0 rg BT 295.76 221.70 Td (, as each period is computed on a discrete basis.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 210.70 Td (\(b\)) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 56.00 210.70 Td (Marketable securities includes current and non-current assets.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 199.70 Td (\(c\)) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 56.00 199.70 Td (Long-term debt includes the current portion.) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 205 0 obj <> endobj 206 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (102) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 749.10 Td (The following specified items af) Tj ET Q q 0 0 0 rg BT 165.78 749.10 Td (fected the comparability of results in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 315.17 749.10 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.17 749.10 Td ( and ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.61 749.10 Td (2016) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 374.61 749.10 Td (:) Tj ET Q BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 730.53505859375 m 56 730.53505859375 l s q 0 0 0 rg BT 36.00 732.10 Td (2017) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 701.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 701.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 701.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 701.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 701.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 701.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 701.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 681.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 681.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 681.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 681.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 681.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 681.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 681.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 681.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 681.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 681.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 681.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 661.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 661.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 661.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 661.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 661.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 661.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 661.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 661.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 661.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 661.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 661.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 635.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 635.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 635.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 635.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 635.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 635.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 635.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 635.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 635.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 635.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 635.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 609.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 609.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 609.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 609.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 609.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 609.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 609.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 609.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 609.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 609.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 609.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 589.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 589.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 589.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 589.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 589.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 589.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 589.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 589.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 589.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 589.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 589.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 563.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 563.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 563.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 563.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 563.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 563.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 563.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 563.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 563.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 563.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 563.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 537.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 537.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 537.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 537.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 537.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 537.60 4.00 -13.00 re f 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0.9333333333333333 1 rg /GS0 gs 480.50 511.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 511.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 511.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 491.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 491.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 491.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 491.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 491.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 491.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 491.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 491.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 491.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 491.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 491.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 471.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 471.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 471.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 471.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 471.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 471.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 471.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 445.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 445.60 4.00 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0.9333333333333333 1 rg /GS0 gs 380.50 425.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 425.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 425.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 425.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 425.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 425.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 425.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 405.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 405.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 405.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 405.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 405.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 405.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 405.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 405.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 405.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 405.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 405.60 46.00 -7.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 701.6 m 376.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 701.6 m 426.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 701.6 m 476.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 701.6 m 526.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 701.6 m 576.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 701.6 m 576.5 701.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 622.6 m 376.5 622.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 622.6 m 426.5 622.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 622.6 m 476.5 622.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 622.6 m 526.5 622.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 622.6 m 576.5 622.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 524.6 m 376.5 524.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 524.6 m 426.5 524.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 524.6 m 476.5 524.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 524.6 m 526.5 524.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 524.6 m 576.5 524.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 458.6 m 376.5 458.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 458.6 m 426.5 458.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 458.6 m 476.5 458.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 458.6 m 526.5 458.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 458.6 m 576.5 458.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 398.6 m 376.5 398.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 377.6 m 376.5 377.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 330.5 375.6 m 376.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 398.6 m 426.5 398.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 377.6 m 426.5 377.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380.5 375.6 m 426.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 398.6 m 476.5 398.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 377.6 m 476.5 377.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 430.5 375.6 m 476.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 398.6 m 526.5 398.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 377.6 m 526.5 377.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 480.5 375.6 m 526.5 375.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 398.6 m 576.5 398.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 377.6 m 576.5 377.6 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 530.5 375.6 m 576.5 375.6 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 705.85 Td (Dollars in Millions) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 344.75 713.68 Td (First) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 339.05 705.68 Td (Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 390.75 713.68 Td (Second) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 389.05 705.68 Td (Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 442.95 713.68 Td (Third) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 439.05 705.68 Td (Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 491.00 713.68 Td (Fourth) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 489.05 705.68 Td (Quarter) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 545.05 705.83 Td (Y) Tj ET Q q 0 0 0 rg BT 549.94 705.83 Td (ear) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 692.33 Td (Cost of pr) Tj ET Q q 0 0 0 rg BT 81.59 692.33 Td (oducts sold) Tj ET Q BT /F2 10.00 Tf ET BT /F2 6.50 Tf ET q 0 0 0 rg BT 129.11 696.86 Td (\(a\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.00 692.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 692.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.00 692.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 692.17 Td (130) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 692.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 467.65 692.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.00 692.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 692.17 Td (18) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 692.17 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 692.17 Td (149) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 672.33 Td (Marketing, selling and administrative) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 672.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 672.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 672.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 517.65 672.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 567.65 672.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 652.17 Td (License and asset acquisition char) Tj ET Q q 0 0 0 rg BT 174.97 652.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 652.17 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 652.17 Td (393) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.65 652.17 Td (310) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 652.17 Td (377) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 652.17 Td (1,130) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 639.17 Td (IPRD impairments) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 639.17 Td (75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 639.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 639.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 639.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 562.65 639.17 Td (75) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 626.17 Td (Site exit costs and other) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 626.17 Td (72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 626.17 Td (96) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 626.17 Td (64) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 626.17 Td (151) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 626.17 Td (383) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 613.33 Td (Resear) Tj ET Q q 0 0 0 rg BT 68.34 613.33 Td (ch and development) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 613.17 Td (197) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 613.17 Td (489) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.65 613.17 Td (374) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 613.17 Td (528) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 613.17 Td (1,588) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 593.17 Td (Provision for restructuring) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 357.65 593.17 Td (164) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 593.17 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 593.17 Td (28) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 593.17 Td (86) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 593.17 Td (293) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 580.17 Td (Litigation and other settlements) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 580.22 Td (\(481) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 580.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 580.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 580.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 580.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 580.17 Td (\(481) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 580.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 567.17 Td (Divestiture gains) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 567.22 Td (\(100) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 567.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 567.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 567.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 509.30 567.22 Td (\(26) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 567.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 567.17 Td (\(126) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 567.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 554.17 Td (Royalties and licensing income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 554.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.30 554.22 Td (\(497) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.65 554.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 554.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 554.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 554.17 Td (\(497) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 554.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 541.17 Td (Pension char) Tj ET Q q 0 0 0 rg BT 90.29 541.17 Td (ges) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 541.17 Td (33) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 541.17 Td (36) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 541.17 Td (22) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 541.17 Td (71) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 541.17 Td (162) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 528.17 Td (Loss on debt redemption) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 528.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 528.17 Td (109) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 528.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 528.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 557.65 528.17 Td (109) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 515.33 Td (Other) Tj ET Q q 0 0 0 rg BT 64.46 515.33 Td ( income \(net\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 515.22 Td (\(384) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 515.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 404.30 515.22 Td (\(337) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 422.65 515.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 515.17 Td (50) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 515.17 Td (131) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.30 515.17 Td (\(540) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 515.17 Td (\)) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 495.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.24 495.33 Td (ease/\(decr) Tj ET Q q 0 0 0 rg BT 99.81 495.33 Td (ease\) to pr) Tj ET Q q 0 0 0 rg BT 144.06 495.33 Td (etax income) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 495.22 Td (\(187) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 495.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 495.17 Td (282) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.65 495.17 Td (425) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 507.65 495.17 Td (678) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 495.17 Td (1,198) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 475.17 Td (Income taxes on items above) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 475.17 Td (72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 475.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.30 475.22 Td (\(41) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 475.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.30 475.22 Td (\(138) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 522.65 475.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 475.17 Td (\(87) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 475.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 462.17 Td (Income taxes attributed to U.S. tax reform) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 462.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 462.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 462.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 462.17 Td (2,91) Tj ET Q q 0 0 0 rg BT 517.65 462.17 Td (1) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 462.17 Td (2,91) Tj ET Q q 0 0 0 rg BT 567.65 462.17 Td (1) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 449.33 Td (Income taxes) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 362.65 449.17 Td (72) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 449.17 Td (20) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.30 449.22 Td (\(41) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 472.65 449.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 449.17 Td (2,773) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 449.17 Td (2,824) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 429.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.24 429.33 Td (ease/\(decr) Tj ET Q q 0 0 0 rg BT 99.81 429.33 Td (ease\) to net earnings) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 429.22 Td (\(1) Tj ET Q q 0 0 0 rg BT 362.63 429.22 Td (15) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 429.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 429.17 Td (302) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.65 429.17 Td (384) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 429.17 Td (3,451) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 429.17 Td (4,022) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 409.33 Td (Noncontr) Tj ET Q q 0 0 0 rg BT 79.46 409.33 Td (olling inter) Tj ET Q q 0 0 0 rg BT 126.22 409.33 Td (est) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 359.30 409.22 Td (\(59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 409.17 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 412.65 409.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 462.65 409.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 512.65 409.17 Td (—) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 559.30 409.17 Td (\(59) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 572.65 409.17 Td (\)) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 389.33 Td (Incr) Tj ET Q q 0 0 0 rg BT 57.15 389.33 Td (ease/\(decr) Tj ET Q q 0 0 0 rg BT 99.72 389.33 Td (ease\) to net earnings used for) Tj ET Q q 0 0 0 rg BT 223.69 389.33 Td ( Diluted Non-GAAP) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 379.33 Td (EPS calculation) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 333.00 381.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 354.30 381.32 Td (\(174) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.65 381.27 Td (\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 383.00 381.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 407.65 381.27 Td (302) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 433.00 381.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 457.65 381.27 Td (384) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 483.00 381.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 500.15 381.27 Td (3,451) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 533.00 381.27 Td ($) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 550.15 381.27 Td (3,963) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET 0 0 0 RG /GS0 gs 0.95 w 0 i [] 0 d 1 J 1 j 3 M 36 358.53505859375 m 56 358.53505859375 l s q 0 0 0 rg BT 36.00 360.10 Td (2016) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 329.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 329.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 329.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 329.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 329.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 329.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 329.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 309.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 309.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 309.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 309.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 309.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 309.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 309.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 309.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 309.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 309.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 309.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 283.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 283.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 283.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 283.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 283.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 283.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 283.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 283.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 283.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 283.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 283.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 257.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 257.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 257.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 257.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 257.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 257.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 257.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 257.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 257.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 257.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 257.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 237.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 237.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 237.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 237.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 237.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 237.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 237.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 237.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 237.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 237.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 237.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 211.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 211.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 211.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 211.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 211.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 211.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 211.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 211.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 211.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 211.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 211.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 185.60 290.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 185.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 185.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 185.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 185.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 185.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 185.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 185.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 185.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 185.60 4.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 185.60 46.00 -13.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 159.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 159.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 159.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 159.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 159.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 159.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 159.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 159.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 159.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 159.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 159.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 139.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 139.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 139.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 139.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 139.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 139.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 139.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 139.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 139.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 526.50 139.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 530.50 139.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 36.50 119.60 290.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 326.50 119.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 330.50 119.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 376.50 119.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.50 119.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 426.50 119.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 430.50 119.60 46.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 476.50 119.60 4.00 -7.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 480.50 119.60 46.00 -7.00 re f 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437.10 Td (error ) Tj ET Q q 0 0 0 rg BT 523.87 437.10 Td (or ) Tj ET Q q 0 0 0 rg BT 534.53 437.10 Td (fraud. ) Tj ET Q q 0 0 0 rg BT 560.45 437.10 Td (Our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 425.10 Td (audits ) Tj ET Q q 0 0 0 rg BT 62.69 425.10 Td (included ) Tj ET Q q 0 0 0 rg BT 99.92 425.10 Td (performing ) Tj ET Q q 0 0 0 rg BT 147.71 425.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 194.38 425.10 Td (to ) Tj ET Q q 0 0 0 rg BT 204.96 425.10 Td (assess ) Tj ET Q q 0 0 0 rg BT 232.21 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 247.22 425.10 Td (risks ) Tj ET Q q 0 0 0 rg BT 268.92 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 280.05 425.10 Td (material ) Tj ET Q q 0 0 0 rg BT 315.61 425.10 Td (misstatement ) Tj ET Q q 0 0 0 rg BT 371.18 425.10 Td (of ) Tj ET Q q 0 0 0 rg BT 382.31 425.10 Td (the ) Tj ET Q q 0 0 0 rg BT 397.33 425.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 435.11 425.10 Td (statements, ) Tj ET Q q 0 0 0 rg BT 482.63 425.10 Td (whether ) Tj ET Q q 0 0 0 rg BT 517.63 425.10 Td (due ) Tj ET Q q 0 0 0 rg BT 534.88 425.10 Td (to ) Tj ET Q q 0 0 0 rg BT 545.46 425.10 Td (error ) Tj ET Q q 0 0 0 rg BT 567.69 425.10 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 413.10 Td (fraud, ) Tj ET Q q 0 0 0 rg BT 62.29 413.10 Td (and ) Tj ET Q q 0 0 0 rg BT 79.43 413.10 Td (performing ) Tj ET Q q 0 0 0 rg BT 127.11 413.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 173.67 413.10 Td (that ) Tj ET Q q 0 0 0 rg BT 191.36 413.10 Td (respond ) Tj ET Q q 0 0 0 rg BT 225.71 413.10 Td (to ) Tj ET Q q 0 0 0 rg BT 236.18 413.10 Td (those ) Tj ET Q q 0 0 0 rg BT 259.99 413.10 Td (risks. ) Tj ET Q q 0 0 0 rg BT 284.07 413.10 Td (Such ) Tj ET Q q 0 0 0 rg BT 306.77 413.10 Td (procedures ) Tj ET Q q 0 0 0 rg BT 353.33 413.10 Td (included ) Tj ET Q q 0 0 0 rg BT 390.46 413.10 Td (examining, ) Tj ET Q q 0 0 0 rg BT 437.86 413.10 Td (on ) Tj ET Q q 0 0 0 rg BT 450.56 413.10 Td (a ) Tj ET Q q 0 0 0 rg BT 457.69 413.10 Td (test ) Tj ET Q q 0 0 0 rg BT 474.27 413.10 Td (basis, ) Tj ET Q q 0 0 0 rg BT 499.46 413.10 Td (evidence ) Tj ET Q q 0 0 0 rg BT 537.69 413.10 Td (regarding ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 50.06 401.10 Td (amounts ) Tj ET Q q 0 0 0 rg BT 85.79 401.10 Td (and ) Tj ET Q q 0 0 0 rg BT 102.08 401.10 Td (disclosures ) Tj ET Q q 0 0 0 rg BT 148.36 401.10 Td (in ) Tj ET Q q 0 0 0 rg BT 157.98 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 172.04 401.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 208.87 401.10 Td (statements. ) Tj ET Q q 0 0 0 rg BT 255.43 401.10 Td (Our ) Tj ET Q q 0 0 0 rg BT 272.82 401.10 Td (audits ) Tj ET Q q 0 0 0 rg BT 298.55 401.10 Td (also ) Tj ET Q q 0 0 0 rg BT 316.51 401.10 Td (included ) Tj ET Q q 0 0 0 rg BT 352.79 401.10 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 396.28 401.10 Td (the ) Tj ET Q q 0 0 0 rg BT 410.34 401.10 Td (accounting ) Tj ET Q q 0 0 0 rg BT 456.06 401.10 Td (principles ) Tj ET Q q 0 0 0 rg BT 497.34 401.10 Td (used ) Tj ET Q q 0 0 0 rg BT 517.51 401.10 Td (and ) Tj ET Q q 0 0 0 rg BT 533.79 401.10 Td (significant ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 389.10 Td (estimates ) Tj ET Q q 0 0 0 rg BT 76.32 389.10 Td (made ) Tj ET Q q 0 0 0 rg BT 101.08 389.10 Td (by ) Tj ET Q q 0 0 0 rg BT 114.18 389.10 Td (management, ) Tj ET Q q 0 0 0 rg BT 170.88 389.10 Td (as ) Tj ET Q q 0 0 0 rg BT 182.31 389.10 Td (well ) Tj ET Q q 0 0 0 rg BT 202.64 389.10 Td (as ) Tj ET Q q 0 0 0 rg BT 214.07 389.10 Td (evaluating ) Tj ET Q q 0 0 0 rg BT 258.83 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 274.15 389.10 Td (overall ) Tj ET Q q 0 0 0 rg BT 305.02 389.10 Td (presentation ) Tj ET Q q 0 0 0 rg BT 357.00 389.10 Td (of ) Tj ET Q q 0 0 0 rg BT 368.43 389.10 Td (the ) Tj ET Q q 0 0 0 rg BT 383.75 389.10 Td (financial ) Tj ET Q q 0 0 0 rg BT 421.84 389.10 Td (statements. ) Tj ET Q q 0 0 0 rg BT 469.43 389.10 Td (W) Tj ET Q q 0 0 0 rg BT 478.07 389.10 Td (e ) Tj ET Q q 0 0 0 rg BT 485.61 389.10 Td (believe ) Tj ET Q q 0 0 0 rg BT 517.59 389.10 Td (that ) Tj ET Q q 0 0 0 rg BT 535.69 389.10 Td (our ) Tj ET Q q 0 0 0 rg BT 552.13 389.10 Td (audits ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 377.10 Td (provide ) Tj ET Q q 0 0 0 rg BT 69.05 377.10 Td (a ) Tj ET Q q 0 0 0 rg BT 75.99 377.10 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 121.24 377.10 Td (basis ) Tj ET Q q 0 0 0 rg BT 143.74 377.10 Td (for ) Tj ET Q q 0 0 0 rg BT 157.90 377.10 Td (our ) Tj ET Q q 0 0 0 rg BT 173.73 377.10 Td (opinion.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 353.10 Td (/s/ DELOITTE & T) Tj ET Q q 0 0 0 rg BT 112.78 353.10 Td (OUCHE LLP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 329.10 Td (Parsippany) Tj ET Q q 0 0 0 rg BT 79.79 329.10 Td (, New Jersey) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 317.10 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 293.10 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 293.10 Td (e have served as the Company's auditor since 2006.) Tj ET Q endstream endobj 209 0 obj <> endobj 210 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (104) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 746.23 Td (Item 9.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 746.23 Td (CHANGES IN ) Tj ET Q q 0 0 0 rg BT 160.01 746.23 Td (AND DISAGREEMENTS ) Tj ET Q q 0 0 0 rg BT 274.30 746.23 Td (WITH ) Tj ET Q q 0 0 0 rg BT 304.58 746.23 Td (ACCOUNT) Tj ET Q q 0 0 0 rg BT 354.40 746.23 Td (ANTS ON ) Tj ET Q q 0 0 0 rg BT 400.52 746.23 Td (ACCOUNTING ) Tj ET Q q 0 0 0 rg BT 471.92 746.23 Td (AND FINANCIAL) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 736.23 Td (DISCLOSURE.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 715.00 Td (None.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 683.23 Td (Item 9A.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 683.23 Td (CONTROLS ) Tj ET Q q 0 0 0 rg BT 153.07 683.23 Td (AND PROCEDURES.) Tj ET Q BT /F1 10.00 Tf ET BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 655.00 Td (Evaluation of Disclosur) Tj ET Q q 0 0 0 rg BT 135.83 655.00 Td (e Contr) Tj ET Q q 0 0 0 rg BT 168.14 655.00 Td (ols and Pr) Tj ET Q q 0 0 0 rg BT 211.30 655.00 Td (ocedur) Tj ET Q q 0 0 0 rg BT 240.56 655.00 Td (es) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 631.00 Td (As ) Tj ET Q q 0 0 0 rg BT 49.46 631.00 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 60.14 631.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 118.57 631.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 138.57 631.00 Td (, ) Tj ET Q q 0 0 0 rg BT 143.42 631.00 Td (management ) Tj ET Q q 0 0 0 rg BT 196.86 631.00 Td (carried ) Tj ET Q q 0 0 0 rg BT 226.96 631.00 Td (out ) Tj ET Q q 0 0 0 rg BT 242.09 631.00 Td (an ) Tj ET Q q 0 0 0 rg BT 253.88 631.00 Td (evaluation, ) Tj ET Q q 0 0 0 rg BT 300.38 631.00 Td (under ) Tj ET Q q 0 0 0 rg BT 325.49 631.00 Td (the ) Tj ET Q q 0 0 0 rg BT 340.06 631.00 Td (supervision ) Tj ET Q q 0 0 0 rg BT 388.51 631.00 Td (and ) Tj ET Q q 0 0 0 rg BT 405.30 631.00 Td (with ) Tj ET Q q 0 0 0 rg BT 425.43 631.00 Td (the ) Tj ET Q q 0 0 0 rg BT 439.99 631.00 Td (participation ) Tj ET Q q 0 0 0 rg BT 492.88 631.00 Td (of ) Tj ET Q q 0 0 0 rg BT 503.56 631.00 Td (its ) Tj ET Q q 0 0 0 rg BT 515.36 631.00 Td (chief ) Tj ET Q q 0 0 0 rg BT 537.69 631.00 Td (executive ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 619.00 Td (of) Tj ET Q q 0 0 0 rg BT 44.15 619.00 Td (ficer ) Tj ET Q q 0 0 0 rg BT 64.86 619.00 Td (and ) Tj ET Q q 0 0 0 rg BT 81.70 619.00 Td (chief ) Tj ET Q q 0 0 0 rg BT 104.08 619.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 141.46 619.00 Td (of) Tj ET Q q 0 0 0 rg BT 149.60 619.00 Td (ficer) Tj ET Q q 0 0 0 rg BT 167.52 619.00 Td (, ) Tj ET Q q 0 0 0 rg BT 172.42 619.00 Td (of ) Tj ET Q q 0 0 0 rg BT 183.14 619.00 Td (the ) Tj ET Q q 0 0 0 rg BT 197.76 619.00 Td (ef) Tj ET Q q 0 0 0 rg BT 205.34 619.00 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 252.16 619.00 Td (of ) Tj ET Q q 0 0 0 rg BT 262.89 619.00 Td (the ) Tj ET Q q 0 0 0 rg BT 277.50 619.00 Td (design ) Tj ET Q q 0 0 0 rg BT 306.01 619.00 Td (and ) Tj ET Q q 0 0 0 rg BT 322.84 619.00 Td (operation ) Tj ET Q q 0 0 0 rg BT 363.00 619.00 Td (of ) Tj ET Q q 0 0 0 rg BT 373.73 619.00 Td (its ) Tj ET Q q 0 0 0 rg BT 385.58 619.00 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 428.52 619.00 Td (controls ) Tj ET Q q 0 0 0 rg BT 463.13 619.00 Td (and ) Tj ET Q q 0 0 0 rg BT 479.97 619.00 Td (procedures ) Tj ET Q q 0 0 0 rg BT 526.23 619.00 Td (as ) Tj ET Q q 0 0 0 rg BT 536.96 619.00 Td (such ) Tj ET Q q 0 0 0 rg BT 557.68 619.00 Td (term ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 607.00 Td (is ) Tj ET Q q 0 0 0 rg BT 44.76 607.00 Td (defined ) Tj ET Q q 0 0 0 rg BT 76.84 607.00 Td (under ) Tj ET Q q 0 0 0 rg BT 101.71 607.00 Td (Exchange ) Tj ET Q q 0 0 0 rg BT 142.76 607.00 Td (Act ) Tj ET Q q 0 0 0 rg BT 159.30 607.00 Td (Rule ) Tj ET Q q 0 0 0 rg BT 180.28 607.00 Td (13a-15\(e\). ) Tj ET Q q 0 0 0 rg BT 223.74 607.00 Td (Based ) Tj ET Q q 0 0 0 rg BT 250.27 607.00 Td (on ) Tj ET Q q 0 0 0 rg BT 262.37 607.00 Td (this ) Tj ET Q q 0 0 0 rg BT 278.91 607.00 Td (evaluation, ) Tj ET Q q 0 0 0 rg BT 325.16 607.00 Td (management ) Tj ET Q q 0 0 0 rg BT 378.34 607.00 Td (has ) Tj ET Q q 0 0 0 rg BT 393.77 607.00 Td (concluded ) Tj ET Q q 0 0 0 rg BT 436.95 607.00 Td (that ) Tj ET Q q 0 0 0 rg BT 454.04 607.00 Td (as ) Tj ET Q q 0 0 0 rg BT 464.47 607.00 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 474.89 607.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 533.07 607.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 553.07 607.00 Td (, ) Tj ET Q q 0 0 0 rg BT 557.67 607.00 Td (such ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 595.00 Td (disclosure ) Tj ET Q q 0 0 0 rg BT 79.05 595.00 Td (controls ) Tj ET Q q 0 0 0 rg BT 113.76 595.00 Td (and ) Tj ET Q q 0 0 0 rg BT 130.70 595.00 Td (procedures ) Tj ET Q q 0 0 0 rg BT 177.07 595.00 Td (were ) Tj ET Q q 0 0 0 rg BT 199.00 595.00 Td (ef) Tj ET Q q 0 0 0 rg BT 206.59 595.00 Td (fective.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 571.00 Td (Management’) Tj ET Q q 0 0 0 rg BT 95.06 571.00 Td (s Report on Internal Contr) Tj ET Q q 0 0 0 rg BT 209.87 571.00 Td (ol Over) Tj ET Q q 0 0 0 rg BT 241.63 571.00 Td ( Financial Reporting) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 547.00 Td (Management ) Tj ET Q q 0 0 0 rg BT 91.16 547.00 Td (is ) Tj ET Q q 0 0 0 rg BT 100.78 547.00 Td (responsible ) Tj ET Q q 0 0 0 rg BT 149.29 547.00 Td (for ) Tj ET Q q 0 0 0 rg BT 163.90 547.00 Td (establishing ) Tj ET Q q 0 0 0 rg BT 214.63 547.00 Td (and ) Tj ET Q q 0 0 0 rg BT 232.02 547.00 Td (maintaining ) Tj ET Q q 0 0 0 rg BT 282.75 547.00 Td (adequate ) Tj ET Q q 0 0 0 rg BT 321.24 547.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 354.73 547.00 Td (control ) Tj ET Q q 0 0 0 rg BT 386.01 547.00 Td (over ) Tj ET Q q 0 0 0 rg BT 406.74 547.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 444.67 547.00 Td (reporting. ) Tj ET Q q 0 0 0 rg BT 486.79 547.00 Td (Under ) Tj ET Q q 0 0 0 rg BT 514.73 547.00 Td (the ) Tj ET Q q 0 0 0 rg BT 529.90 547.00 Td (supervision ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 535.00 Td (and ) Tj ET Q q 0 0 0 rg BT 53.57 535.00 Td (with ) Tj ET Q q 0 0 0 rg BT 74.48 535.00 Td (the ) Tj ET Q q 0 0 0 rg BT 89.82 535.00 Td (participation ) Tj ET Q q 0 0 0 rg BT 143.49 535.00 Td (of ) Tj ET Q q 0 0 0 rg BT 154.95 535.00 Td (management, ) Tj ET Q q 0 0 0 rg BT 211.67 535.00 Td (including ) Tj ET Q q 0 0 0 rg BT 252.57 535.00 Td (the ) Tj ET Q q 0 0 0 rg BT 267.92 535.00 Td (chief ) Tj ET Q q 0 0 0 rg BT 291.03 535.00 Td (executive ) Tj ET Q q 0 0 0 rg BT 332.47 535.00 Td (of) Tj ET Q q 0 0 0 rg BT 340.62 535.00 Td (ficer ) Tj ET Q q 0 0 0 rg BT 362.07 535.00 Td (and ) Tj ET Q q 0 0 0 rg BT 379.64 535.00 Td (chief ) Tj ET Q q 0 0 0 rg BT 402.75 535.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 440.86 535.00 Td (of) Tj ET Q q 0 0 0 rg BT 449.01 535.00 Td (ficer) Tj ET Q q 0 0 0 rg BT 466.93 535.00 Td (, ) Tj ET Q q 0 0 0 rg BT 472.56 535.00 Td (management ) Tj ET Q q 0 0 0 rg BT 526.78 535.00 Td (assessed ) Tj ET Q q 0 0 0 rg BT 563.79 535.00 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 523.00 Td (ef) Tj ET Q q 0 0 0 rg BT 43.59 523.00 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 89.51 523.00 Td (of ) Tj ET Q q 0 0 0 rg BT 99.33 523.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 131.37 523.00 Td (control ) Tj ET Q q 0 0 0 rg BT 161.19 523.00 Td (over ) Tj ET Q q 0 0 0 rg BT 180.45 523.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 216.92 523.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 255.07 523.00 Td (as ) Tj ET Q q 0 0 0 rg BT 264.90 523.00 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 274.72 523.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 332.30 523.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 352.30 523.00 Td ( ) Tj ET Q q 0 0 0 rg BT 353.79 523.00 Td (based ) Tj ET Q q 0 0 0 rg BT 378.06 523.00 Td (on ) Tj ET Q q 0 0 0 rg BT 389.55 523.00 Td (the ) Tj ET Q q 0 0 0 rg BT 403.26 523.00 Td (framework ) Tj ET Q q 0 0 0 rg BT 448.62 523.00 Td (in ) Tj ET Q q 0 0 0 rg BT 457.89 523.00 Td (“Internal ) Tj ET Q q 0 0 0 rg BT 494.92 523.00 Td (Control—Integrated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 511.00 Td (Framework” ) Tj ET Q q 0 0 0 rg BT 89.79 511.00 Td (\(2013\) ) Tj ET Q q 0 0 0 rg BT 119.69 511.00 Td (issued ) Tj ET Q q 0 0 0 rg BT 147.94 511.00 Td (by ) Tj ET Q q 0 0 0 rg BT 161.19 511.00 Td (the ) Tj ET Q q 0 0 0 rg BT 176.66 511.00 Td (Committee ) Tj ET Q q 0 0 0 rg BT 224.34 511.00 Td (of ) Tj ET Q q 0 0 0 rg BT 235.92 511.00 Td (Sponsoring ) Tj ET Q q 0 0 0 rg BT 284.73 511.00 Td (Or) Tj ET Q q 0 0 0 rg BT 295.10 511.00 Td (ganizations ) Tj ET Q q 0 0 0 rg BT 343.89 511.00 Td (of ) Tj ET Q q 0 0 0 rg BT 355.47 511.00 Td (the ) Tj ET Q q 0 0 0 rg BT 370.70 511.00 Td (T) Tj ET Q q 0 0 0 rg BT 376.46 511.00 Td (readway ) Tj ET Q q 0 0 0 rg BT 413.58 511.00 Td (Commission. ) Tj ET Q q 0 0 0 rg BT 469.89 511.00 Td (Based ) Tj ET Q q 0 0 0 rg BT 497.58 511.00 Td (on ) Tj ET Q q 0 0 0 rg BT 510.83 511.00 Td (that ) Tj ET Q q 0 0 0 rg BT 529.07 511.00 Td (assessment, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 499.00 Td (management ) Tj ET Q q 0 0 0 rg BT 89.53 499.00 Td (has ) Tj ET Q q 0 0 0 rg BT 105.30 499.00 Td (concluded ) Tj ET Q q 0 0 0 rg BT 148.83 499.00 Td (that ) Tj ET Q q 0 0 0 rg BT 166.27 499.00 Td (the ) Tj ET Q q 0 0 0 rg BT 180.93 499.00 Td (Company’) Tj ET Q q 0 0 0 rg BT 222.59 499.00 Td (s ) Tj ET Q q 0 0 0 rg BT 228.92 499.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 261.91 499.00 Td (control ) Tj ET Q q 0 0 0 rg BT 292.67 499.00 Td (over ) Tj ET Q q 0 0 0 rg BT 312.88 499.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 350.30 499.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 389.40 499.00 Td (was ) Tj ET Q q 0 0 0 rg BT 407.39 499.00 Td (ef) Tj ET Q q 0 0 0 rg BT 414.98 499.00 Td (fective ) Tj ET Q q 0 0 0 rg BT 444.62 499.00 Td (at ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 454.28 499.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 512.80 499.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.80 499.00 Td ( ) Tj ET Q q 0 0 0 rg BT 535.24 499.00 Td (to ) Tj ET Q q 0 0 0 rg BT 545.46 499.00 Td (provide ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 487.00 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 80.59 487.00 Td (assurance ) Tj ET Q q 0 0 0 rg BT 121.29 487.00 Td (regarding ) Tj ET Q q 0 0 0 rg BT 161.43 487.00 Td (the ) Tj ET Q q 0 0 0 rg BT 175.48 487.00 Td (reliability ) Tj ET Q q 0 0 0 rg BT 216.19 487.00 Td (of ) Tj ET Q q 0 0 0 rg BT 226.36 487.00 Td (its ) Tj ET Q q 0 0 0 rg BT 237.64 487.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 274.45 487.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 312.94 487.00 Td (and ) Tj ET Q q 0 0 0 rg BT 329.21 487.00 Td (the ) Tj ET Q q 0 0 0 rg BT 343.26 487.00 Td (preparation ) Tj ET Q q 0 0 0 rg BT 390.62 487.00 Td (of ) Tj ET Q q 0 0 0 rg BT 400.78 487.00 Td (its ) Tj ET Q q 0 0 0 rg BT 412.07 487.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 448.88 487.00 Td (statements ) Tj ET Q q 0 0 0 rg BT 492.92 487.00 Td (for ) Tj ET Q q 0 0 0 rg BT 506.42 487.00 Td (external ) Tj ET Q q 0 0 0 rg BT 540.45 487.00 Td (purposes ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 475.00 Td (in ) Tj ET Q q 0 0 0 rg BT 45.95 475.00 Td (accordance ) Tj ET Q q 0 0 0 rg BT 93.08 475.00 Td (with ) Tj ET Q q 0 0 0 rg BT 113.02 475.00 Td (United ) Tj ET Q q 0 0 0 rg BT 142.41 475.00 Td (States ) Tj ET Q q 0 0 0 rg BT 168.46 475.00 Td (generally ) Tj ET Q q 0 0 0 rg BT 207.83 475.00 Td (accepted ) Tj ET Q q 0 0 0 rg BT 244.97 475.00 Td (accounting ) Tj ET Q q 0 0 0 rg BT 291.01 475.00 Td (principles. ) Tj ET Q q 0 0 0 rg BT 335.11 475.00 Td (Due ) Tj ET Q q 0 0 0 rg BT 353.94 475.00 Td (to ) Tj ET Q q 0 0 0 rg BT 363.89 475.00 Td (its ) Tj ET Q q 0 0 0 rg BT 375.50 475.00 Td (inherent ) Tj ET Q q 0 0 0 rg BT 410.43 475.00 Td (limitations, ) Tj ET Q q 0 0 0 rg BT 457.88 475.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 490.59 475.00 Td (control ) Tj ET Q q 0 0 0 rg BT 521.08 475.00 Td (over ) Tj ET Q q 0 0 0 rg BT 541.02 475.00 Td (financial ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 463.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 75.43 463.00 Td (may ) Tj ET Q q 0 0 0 rg BT 95.41 463.00 Td (not ) Tj ET Q q 0 0 0 rg BT 110.96 463.00 Td (prevent ) Tj ET Q q 0 0 0 rg BT 143.72 463.00 Td (or ) Tj ET Q q 0 0 0 rg BT 154.82 463.00 Td (detect ) Tj ET Q q 0 0 0 rg BT 181.46 463.00 Td (misstatements. ) Tj ET Q q 0 0 0 rg BT 242.78 463.00 Td (Also, ) Tj ET Q q 0 0 0 rg BT 266.94 463.00 Td (projections ) Tj ET Q q 0 0 0 rg BT 314.14 463.00 Td (of ) Tj ET Q q 0 0 0 rg BT 325.24 463.00 Td (any ) Tj ET Q q 0 0 0 rg BT 342.45 463.00 Td (evaluation ) Tj ET Q q 0 0 0 rg BT 386.87 463.00 Td (of ) Tj ET Q q 0 0 0 rg BT 397.97 463.00 Td (ef) Tj ET Q q 0 0 0 rg BT 405.56 463.00 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 452.75 463.00 Td (to ) Tj ET Q q 0 0 0 rg BT 463.30 463.00 Td (future ) Tj ET Q q 0 0 0 rg BT 489.95 463.00 Td (periods ) Tj ET Q q 0 0 0 rg BT 522.16 463.00 Td (are ) Tj ET Q q 0 0 0 rg BT 537.13 463.00 Td (subject ) Tj ET Q q 0 0 0 rg BT 568.23 463.00 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 451.00 Td (the ) Tj ET Q q 0 0 0 rg BT 51.26 451.00 Td (risk ) Tj ET Q q 0 0 0 rg BT 69.29 451.00 Td (that ) Tj ET Q q 0 0 0 rg BT 87.33 451.00 Td (controls ) Tj ET Q q 0 0 0 rg BT 122.58 451.00 Td (may ) Tj ET Q q 0 0 0 rg BT 142.84 451.00 Td (become ) Tj ET Q q 0 0 0 rg BT 176.97 451.00 Td (inadequate ) Tj ET Q q 0 0 0 rg BT 223.32 451.00 Td (because ) Tj ET Q q 0 0 0 rg BT 258.00 451.00 Td (of ) Tj ET Q q 0 0 0 rg BT 269.37 451.00 Td (changes ) Tj ET Q q 0 0 0 rg BT 304.62 451.00 Td (in ) Tj ET Q q 0 0 0 rg BT 315.44 451.00 Td (conditions, ) Tj ET Q q 0 0 0 rg BT 362.64 451.00 Td (or ) Tj ET Q q 0 0 0 rg BT 374.01 451.00 Td (that ) Tj ET Q q 0 0 0 rg BT 392.04 451.00 Td (the ) Tj ET Q q 0 0 0 rg BT 407.30 451.00 Td (degree ) Tj ET Q q 0 0 0 rg BT 436.98 451.00 Td (of ) Tj ET Q q 0 0 0 rg BT 448.35 451.00 Td (compliance ) Tj ET Q q 0 0 0 rg BT 497.48 451.00 Td (with ) Tj ET Q q 0 0 0 rg BT 518.29 451.00 Td (the ) Tj ET Q q 0 0 0 rg BT 533.55 451.00 Td (policies ) Tj ET Q q 0 0 0 rg BT 567.69 451.00 Td (or ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 439.00 Td (procedures ) Tj ET Q q 0 0 0 rg BT 82.37 439.00 Td (may ) Tj ET Q q 0 0 0 rg BT 102.08 439.00 Td (deteriorate.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 415.00 Td (Deloitte & ) Tj ET Q q 0 0 0 rg BT 80.98 415.00 Td (T) Tj ET Q q 0 0 0 rg BT 86.39 415.00 Td (ouche ) Tj ET Q q 0 0 0 rg BT 112.96 415.00 Td (LLP) Tj ET Q q 0 0 0 rg BT 129.63 415.00 Td (, ) Tj ET Q q 0 0 0 rg BT 134.81 415.00 Td (an ) Tj ET Q q 0 0 0 rg BT 146.94 415.00 Td (independent ) Tj ET Q q 0 0 0 rg BT 198.50 415.00 Td (registered ) Tj ET Q q 0 0 0 rg BT 240.61 415.00 Td (public ) Tj ET Q q 0 0 0 rg BT 268.29 415.00 Td (accounting ) Tj ET Q q 0 0 0 rg BT 314.85 415.00 Td (firm, ) Tj ET Q q 0 0 0 rg BT 337.25 415.00 Td (has ) Tj ET Q q 0 0 0 rg BT 353.27 415.00 Td (audited ) Tj ET Q q 0 0 0 rg BT 385.39 415.00 Td (the ) Tj ET Q q 0 0 0 rg BT 400.30 415.00 Td (Company’) Tj ET Q q 0 0 0 rg BT 441.96 415.00 Td (s ) Tj ET Q q 0 0 0 rg BT 448.54 415.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 486.21 415.00 Td (statements ) Tj ET Q q 0 0 0 rg BT 531.11 415.00 Td (included ) Tj ET Q q 0 0 0 rg BT 568.23 415.00 Td (in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 403.00 Td (this ) Tj ET Q q 0 0 0 rg BT 53.85 403.00 Td (report ) Tj ET Q q 0 0 0 rg BT 81.13 403.00 Td (on ) Tj ET Q q 0 0 0 rg BT 94.53 403.00 Td (Form ) Tj ET Q q 0 0 0 rg BT 119.60 403.00 Td (10-K ) Tj ET Q q 0 0 0 rg BT 143.56 403.00 Td (and ) Tj ET Q q 0 0 0 rg BT 161.40 403.00 Td (issued ) Tj ET Q q 0 0 0 rg BT 189.80 403.00 Td (its ) Tj ET Q q 0 0 0 rg BT 202.65 403.00 Td (report ) Tj ET Q q 0 0 0 rg BT 229.93 403.00 Td (on ) Tj ET Q q 0 0 0 rg BT 243.33 403.00 Td (the ) Tj ET Q q 0 0 0 rg BT 258.95 403.00 Td (ef) Tj ET Q q 0 0 0 rg BT 266.54 403.00 Td (fectiveness ) Tj ET Q q 0 0 0 rg BT 314.37 403.00 Td (of ) Tj ET Q q 0 0 0 rg BT 326.10 403.00 Td (the ) Tj ET Q q 0 0 0 rg BT 341.72 403.00 Td (Company’) Tj ET Q q 0 0 0 rg BT 383.38 403.00 Td (s ) Tj ET Q q 0 0 0 rg BT 390.68 403.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 424.62 403.00 Td (control ) Tj ET Q q 0 0 0 rg BT 456.35 403.00 Td (over ) Tj ET Q q 0 0 0 rg BT 477.52 403.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 515.90 403.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 555.96 403.00 Td (as ) Tj ET Q q 0 0 0 rg BT 567.69 403.00 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 391.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 94.58 391.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 114.58 391.00 Td (, ) Tj ET Q q 0 0 0 rg BT 119.58 391.00 Td (which ) Tj ET Q q 0 0 0 rg BT 146.52 391.00 Td (is ) Tj ET Q q 0 0 0 rg BT 155.69 391.00 Td (included ) Tj ET Q q 0 0 0 rg BT 192.63 391.00 Td (herein.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 367.00 Td (Changes ) Tj ET Q q 0 0 0 rg BT 75.17 367.00 Td (in ) Tj ET Q q 0 0 0 rg BT 86.01 367.00 Td (Internal ) Tj ET Q q 0 0 0 rg BT 123.51 367.00 Td (Contr) Tj ET Q q 0 0 0 rg BT 148.89 367.00 Td (ol ) Tj ET Q q 0 0 0 rg BT 159.16 367.00 Td (Over) Tj ET Q q 0 0 0 rg BT 180.64 367.00 Td ( ) Tj ET Q q 0 0 0 rg BT 183.14 367.00 Td (Financial ) Tj ET Q q 0 0 0 rg BT 225.64 367.00 Td (Reporting) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 343.00 Td (There ) Tj ET Q q 0 0 0 rg BT 61.51 343.00 Td (were ) Tj ET Q q 0 0 0 rg BT 83.14 343.00 Td (no ) Tj ET Q q 0 0 0 rg BT 95.33 343.00 Td (changes ) Tj ET Q q 0 0 0 rg BT 129.74 343.00 Td (in ) Tj ET Q q 0 0 0 rg BT 139.71 343.00 Td (the ) Tj ET Q q 0 0 0 rg BT 154.12 343.00 Td (Company's ) Tj ET Q q 0 0 0 rg BT 200.90 343.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 233.64 343.00 Td (control ) Tj ET Q q 0 0 0 rg BT 264.16 343.00 Td (over ) Tj ET Q q 0 0 0 rg BT 284.13 343.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 321.30 343.00 Td (reporting ) Tj ET Q q 0 0 0 rg BT 360.15 343.00 Td (during ) Tj ET Q q 0 0 0 rg BT 388.46 343.00 Td (the ) Tj ET Q q 0 0 0 rg BT 402.87 343.00 Td (quarter ) Tj ET Q q 0 0 0 rg BT 433.38 343.00 Td (ended ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.46 343.00 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 517.74 343.00 Td (2017) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 537.74 343.00 Td ( ) Tj ET Q q 0 0 0 rg BT 539.93 343.00 Td (that ) Tj ET Q q 0 0 0 rg BT 557.12 343.00 Td (have ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 331.00 Td (materially ) Tj ET Q q 0 0 0 rg BT 79.04 331.00 Td (af) Tj ET Q q 0 0 0 rg BT 86.63 331.00 Td (fected, ) Tj ET Q q 0 0 0 rg BT 116.05 331.00 Td (or ) Tj ET Q q 0 0 0 rg BT 126.88 331.00 Td (are ) Tj ET Q q 0 0 0 rg BT 141.59 331.00 Td (reasonable ) Tj ET Q q 0 0 0 rg BT 186.84 331.00 Td (likely ) Tj ET Q q 0 0 0 rg BT 212.11 331.00 Td (to ) Tj ET Q q 0 0 0 rg BT 222.39 331.00 Td (materially ) Tj ET Q q 0 0 0 rg BT 265.43 331.00 Td (af) Tj ET Q q 0 0 0 rg BT 273.02 331.00 Td (fect, ) Tj ET Q q 0 0 0 rg BT 293.00 331.00 Td (the ) Tj ET Q q 0 0 0 rg BT 307.72 331.00 Td (Company's ) Tj ET Q q 0 0 0 rg BT 354.80 331.00 Td (internal ) Tj ET Q q 0 0 0 rg BT 387.84 331.00 Td (control ) Tj ET Q q 0 0 0 rg BT 418.67 331.00 Td (over ) Tj ET Q q 0 0 0 rg BT 438.93 331.00 Td (financial ) Tj ET Q q 0 0 0 rg BT 476.42 331.00 Td (reporting.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 299.23 Td (Item 9B.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 299.23 Td (OTHER INFORMA) Tj ET Q q 0 0 0 rg BT 181.76 299.23 Td (TION.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 271.00 Td (None.) Tj ET Q endstream endobj 211 0 obj <> endobj 212 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (105) Tj ET Q BT /F1 11.00 Tf ET q 0 0 0 rg BT 36.00 748.40 Td (REPOR) Tj ET Q q 0 0 0 rg BT 70.79 748.40 Td (T) Tj ET Q q 0 0 0 rg BT 77.31 748.40 Td ( OF INDEPENDENT) Tj ET Q q 0 0 0 rg BT 173.05 748.40 Td ( REGISTERED PUBLIC ) Tj ET Q q 0 0 0 rg BT 287.03 748.40 Td (ACCOUNTING FIRM) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 724.40 Td (T) Tj ET Q q 0 0 0 rg BT 41.41 724.40 Td (o the shareholders and the Board of Directors of Bristol-Myers Squibb Company) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 700.40 Td (Opinion on Internal Contr) Tj ET Q q 0 0 0 rg BT 149.45 700.40 Td (ol over) Tj ET Q q 0 0 0 rg BT 178.43 700.40 Td ( Financial Reporting) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 676.40 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 676.40 Td (e have audited the internal control over financial reporting of Bristol-Myers Squibb and subsidiaries \(the “Company”\) as of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 664.40 Td (December 31, 2017, based on criteria established in Internal Control - Integrated Framework \(2013\) issued by the Committee of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 652.40 Td (Sponsoring Or) Tj ET Q q 0 0 0 rg BT 94.43 652.40 Td (ganizations of the ) Tj ET Q q 0 0 0 rg BT 167.84 652.40 Td (T) Tj ET Q q 0 0 0 rg BT 173.60 652.40 Td (readway Commission \(COSO\). In our opinion, the Company maintained, in all material respects, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 640.40 Td (ef) Tj ET Q q 0 0 0 rg BT 43.59 640.40 Td (fective internal control over financial reporting as of December 31, 2017, based on criteria established in Internal Control - ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 628.40 Td (Integrated Framework \(2013\) issued by COSO.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 604.40 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 604.40 Td (e have also audited, in accordance with the standards of the Public Company ) Tj ET Q q 0 0 0 rg BT 353.44 604.40 Td (Accounting Oversight Board \(United States\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 592.40 Td (\(PCAOB\), the consolidated financial statements as of and for the year ended December 31, 2017, of the Company and our report dated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 580.40 Td (February 13, 2018, expressed an unqualified opinion on those consolidated financial statements.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 556.40 Td (Basis for) Tj ET Q q 0 0 0 rg BT 73.32 556.40 Td ( Opinion) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 532.40 Td (The Company’) Tj ET Q q 0 0 0 rg BT 95.71 532.40 Td (s management is responsible for maintaining ef) Tj ET Q q 0 0 0 rg BT 284.93 532.40 Td (fective internal control over financial reporting and for its assessment of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 520.40 Td (the ef) Tj ET Q q 0 0 0 rg BT 58.30 520.40 Td (fectiveness of internal control over financial reporting, included in the accompanying Management’) Tj ET Q q 0 0 0 rg BT 457.05 520.40 Td (s Report on Internal Control ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 508.40 Td (Over Financial Reporting. Our responsibility is to express an opinion on the Company’) Tj ET Q q 0 0 0 rg BT 384.01 508.40 Td (s internal control over financial reporting based ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 496.40 Td (on our audit. ) Tj ET Q q 0 0 0 rg BT 89.14 496.40 Td (W) Tj ET Q q 0 0 0 rg BT 97.78 496.40 Td (e are a public accounting firm registered with the PCAOB and are required to be independent with respect to the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 484.40 Td (Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 472.40 Td (Commission and the PCAOB.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 448.40 Td (W) Tj ET Q q 0 0 0 rg BT 44.64 448.40 Td (e conducted our audit in accordance with the standards of the PCAOB. ) Tj ET Q q 0 0 0 rg BT 330.21 448.40 Td (Those standards require that we plan and perform the audit ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 436.40 Td (to obtain reasonable assurance about whether ef) Tj ET Q q 0 0 0 rg BT 227.41 436.40 Td (fective internal control over financial reporting was maintained in all material respects. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 424.40 Td (Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 412.40 Td (exists, testing and evaluating the design and operating ef) Tj ET Q q 0 0 0 rg BT 262.15 412.40 Td (fectiveness of internal control based on the assessed risk, and performing such ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 400.40 Td (other procedures as we considered necessary in the circumstances. ) Tj ET Q q 0 0 0 rg BT 304.04 400.40 Td (W) Tj ET Q q 0 0 0 rg BT 312.68 400.40 Td (e believe that our audit provides a reasonable basis for our ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 388.40 Td (opinion.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 364.40 Td (Definition and Limitations of Internal Contr) Tj ET Q q 0 0 0 rg BT 225.55 364.40 Td (ol over) Tj ET Q q 0 0 0 rg BT 254.53 364.40 Td ( Financial Reporting) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 340.40 Td (A) Tj ET Q q 0 0 0 rg BT 42.67 340.40 Td ( company’) Tj ET Q q 0 0 0 rg BT 84.60 340.40 Td (s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 328.40 Td (financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 316.40 Td (principles. ) Tj ET Q q 0 0 0 rg BT 79.88 316.40 Td (A) Tj ET Q q 0 0 0 rg BT 86.55 316.40 Td ( company’) Tj ET Q q 0 0 0 rg BT 128.49 316.40 Td (s internal control over financial reporting includes those policies and procedures that \(1\) pertain to the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 304.40 Td (maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 292.40 Td (company; \(2\) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 280.40 Td (accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 268.40 Td (accordance with authorizations of management and directors of the company; and \(3\) provide reasonable assurance regarding ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 256.40 Td (prevention or timely detection of unauthorized acquisition, use, or disposition of the company’) Tj ET Q q 0 0 0 rg BT 414.25 256.40 Td (s assets that could have a material ef) Tj ET Q q 0 0 0 rg BT 559.84 256.40 Td (fect ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 244.40 Td (on the financial statements.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 220.40 Td (Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. ) Tj ET Q q 0 0 0 rg BT 504.20 220.40 Td (Also, projections ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 208.40 Td (of any evaluation of ef) Tj ET Q q 0 0 0 rg BT 126.34 208.40 Td (fectiveness to future periods are subject to the risk that controls may become inadequate because of changes in ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 196.40 Td (conditions, or that the degree of compliance with the policies or procedures may deteriorate.) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 36.00 172.40 Td (/s/ DELOITTE & T) Tj ET Q q 0 0 0 rg BT 112.78 172.40 Td (OUCHE LLP) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 148.40 Td (Parsippany) Tj ET Q q 0 0 0 rg BT 79.79 148.40 Td (, New Jersey) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 136.40 Td (February 13, 2018) Tj ET Q endstream endobj 213 0 obj <><><><><><><><><><><><>] /Rotate 0 /Contents 214 0 R>> endobj 214 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (106) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 749.25 Td (P) Tj ET Q q 0 0 0 rg BT 41.37 749.25 Td (AR) Tj ET Q q 0 0 0 rg BT 55.46 749.25 Td (T) Tj ET Q q 0 0 0 rg BT 61.95 749.25 Td ( III) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 717.48 Td (Item 10.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 717.48 Td (DIRECT) Tj ET Q q 0 0 0 rg BT 133.72 717.48 Td (ORS ) Tj ET Q q 0 0 0 rg BT 156.23 717.48 Td (AND EXECUTIVE OFFICERS OF) Tj ET Q q 0 0 0 rg BT 308.93 717.48 Td ( ) Tj ET Q q 0 0 0 rg BT 311.25 717.48 Td (THE REGISTRANT) Tj ET Q q 0 0 0 rg BT 400.25 717.48 Td (.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.45 695.25 Td (\(a\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.45 695.25 Td (Reference ) Tj ET Q q 0 0 0 rg BT 110.42 695.25 Td (is ) Tj ET Q q 0 0 0 rg BT 120.53 695.25 Td (made ) Tj ET Q q 0 0 0 rg BT 145.63 695.25 Td (to ) Tj ET Q q 0 0 0 rg BT 156.85 695.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 172.51 695.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 192.51 695.25 Td ( ) Tj ET Q q 0 0 0 rg BT 195.96 695.25 Td (Proxy ) Tj ET Q q 0 0 0 rg BT 223.29 695.25 Td (Statement ) Tj ET Q q 0 0 0 rg BT 266.73 695.25 Td (to ) Tj ET Q q 0 0 0 rg BT 277.95 695.25 Td (be ) Tj ET Q q 0 0 0 rg BT 290.83 695.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 312.60 695.25 Td (on ) Tj ET Q q 0 0 0 rg BT 326.04 695.25 Td (or ) Tj ET Q q 0 0 0 rg BT 337.82 695.25 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 363.48 695.25 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 408.02 695.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 428.02 695.25 Td ( ) Tj ET Q q 0 0 0 rg BT 431.46 695.25 Td (with ) Tj ET Q q 0 0 0 rg BT 452.69 695.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 484.45 695.25 Td (to ) Tj ET Q q 0 0 0 rg BT 495.67 695.25 Td (the ) Tj ET Q q 0 0 0 rg BT 511.33 695.25 Td (Directors ) Tj ET Q q 0 0 0 rg BT 551.98 695.25 Td (of ) Tj ET Q q 0 0 0 rg BT 563.75 695.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.45 683.25 Td (Registrant, ) Tj ET Q q 0 0 0 rg BT 112.36 683.25 Td (which ) Tj ET Q q 0 0 0 rg BT 139.11 683.25 Td (is ) Tj ET Q q 0 0 0 rg BT 148.09 683.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 200.93 683.25 Td (herein ) Tj ET Q q 0 0 0 rg BT 228.23 683.25 Td (by ) Tj ET Q q 0 0 0 rg BT 240.54 683.25 Td (reference ) Tj ET Q q 0 0 0 rg BT 280.03 683.25 Td (and ) Tj ET Q q 0 0 0 rg BT 296.78 683.25 Td (made ) Tj ET Q q 0 0 0 rg BT 320.74 683.25 Td (a ) Tj ET Q q 0 0 0 rg BT 327.49 683.25 Td (part ) Tj ET Q q 0 0 0 rg BT 345.35 683.25 Td (hereof ) Tj ET Q q 0 0 0 rg BT 373.19 683.25 Td (in ) Tj ET Q q 0 0 0 rg BT 383.28 683.25 Td (response ) Tj ET Q q 0 0 0 rg BT 420.58 683.25 Td (to ) Tj ET Q q 0 0 0 rg BT 430.67 683.25 Td (the ) Tj ET Q q 0 0 0 rg BT 445.20 683.25 Td (information ) Tj ET Q q 0 0 0 rg BT 494.72 683.25 Td (required ) Tj ET Q q 0 0 0 rg BT 530.34 683.25 Td (by ) Tj ET Q q 0 0 0 rg BT 542.65 683.25 Td (Item 10.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.45 665.25 Td (\(b\) ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.45 665.25 Td (The ) Tj ET Q q 0 0 0 rg BT 84.33 665.25 Td (information ) Tj ET Q q 0 0 0 rg BT 133.88 665.25 Td (required ) Tj ET Q q 0 0 0 rg BT 169.53 665.25 Td (by ) Tj ET Q q 0 0 0 rg BT 181.86 665.25 Td (Item 10 ) Tj ET Q q 0 0 0 rg BT 215.02 665.25 Td (with ) Tj ET Q q 0 0 0 rg BT 235.13 665.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 265.78 665.25 Td (to ) Tj ET Q q 0 0 0 rg BT 275.89 665.25 Td (the ) Tj ET Q q 0 0 0 rg BT 290.44 665.25 Td (Executive ) Tj ET Q q 0 0 0 rg BT 332.76 665.25 Td (Of) Tj ET Q q 0 0 0 rg BT 343.13 665.25 Td (ficers ) Tj ET Q q 0 0 0 rg BT 367.67 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 378.33 665.25 Td (the ) Tj ET Q q 0 0 0 rg BT 392.89 665.25 Td (Registrant ) Tj ET Q q 0 0 0 rg BT 436.32 665.25 Td (has ) Tj ET Q q 0 0 0 rg BT 451.99 665.25 Td (been ) Tj ET Q q 0 0 0 rg BT 473.20 665.25 Td (included ) Tj ET Q q 0 0 0 rg BT 509.97 665.25 Td (in ) Tj ET Q q 0 0 0 rg BT 520.08 665.25 Td (Part ) Tj ET Q q 0 0 0 rg BT 538.52 665.25 Td (IA) Tj ET Q q 0 0 0 rg BT 548.52 665.25 Td ( ) Tj ET Q q 0 0 0 rg BT 550.85 665.25 Td (of ) Tj ET Q q 0 0 0 rg BT 561.52 665.25 Td (this ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.45 653.25 Td (Form ) Tj ET Q q 0 0 0 rg BT 90.62 653.25 Td (10-K ) Tj ET Q q 0 0 0 rg BT 113.67 653.25 Td (in ) Tj ET Q q 0 0 0 rg BT 123.95 653.25 Td (reliance ) Tj ET Q q 0 0 0 rg BT 158.09 653.25 Td (on ) Tj ET Q q 0 0 0 rg BT 170.59 653.25 Td (General ) Tj ET Q q 0 0 0 rg BT 204.74 653.25 Td (Instruction ) Tj ET Q q 0 0 0 rg BT 250.56 653.25 Td (G ) Tj ET Q q 0 0 0 rg BT 260.28 653.25 Td (of ) Tj ET Q q 0 0 0 rg BT 271.11 653.25 Td (Form ) Tj ET Q q 0 0 0 rg BT 295.28 653.25 Td (10-K ) Tj ET Q q 0 0 0 rg BT 318.33 653.25 Td (and ) Tj ET Q q 0 0 0 rg BT 335.27 653.25 Td (Instruction ) Tj ET Q q 0 0 0 rg BT 381.10 653.25 Td (3 ) Tj ET Q q 0 0 0 rg BT 388.60 653.25 Td (to ) Tj ET Q q 0 0 0 rg BT 398.88 653.25 Td (Item 401\(b\) ) Tj ET Q q 0 0 0 rg BT 448.86 653.25 Td (of ) Tj ET Q q 0 0 0 rg BT 459.69 653.25 Td (Regulation ) Tj ET Q q 0 0 0 rg BT 506.07 653.25 Td (S-K.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 621.48 Td (Item 1) Tj ET Q q 0 0 0 rg BT 66.21 621.48 Td (1.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 621.48 Td (EXECUTIVE COMPENSA) Tj ET Q q 0 0 0 rg BT 213.44 621.48 Td (TION.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 600.25 Td (Reference ) Tj ET Q q 0 0 0 rg BT 78.98 600.25 Td (is ) Tj ET Q q 0 0 0 rg BT 88.10 600.25 Td (made ) Tj ET Q q 0 0 0 rg BT 112.21 600.25 Td (to ) Tj ET Q q 0 0 0 rg BT 122.44 600.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 137.11 600.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.11 600.25 Td ( ) Tj ET Q q 0 0 0 rg BT 159.56 600.25 Td (Proxy ) Tj ET Q q 0 0 0 rg BT 185.91 600.25 Td (Statement ) Tj ET Q q 0 0 0 rg BT 228.35 600.25 Td (to ) Tj ET Q q 0 0 0 rg BT 238.59 600.25 Td (be ) Tj ET Q q 0 0 0 rg BT 250.48 600.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 271.26 600.25 Td (on ) Tj ET Q q 0 0 0 rg BT 283.71 600.25 Td (or ) Tj ET Q q 0 0 0 rg BT 294.49 600.25 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 319.16 600.25 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 362.72 600.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 382.72 600.25 Td ( ) Tj ET Q q 0 0 0 rg BT 385.17 600.25 Td (with ) Tj ET Q q 0 0 0 rg BT 405.40 600.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 436.17 600.25 Td (to ) Tj ET Q q 0 0 0 rg BT 446.40 600.25 Td (Executive ) Tj ET Q q 0 0 0 rg BT 488.84 600.25 Td (Compensation, ) Tj ET Q q 0 0 0 rg BT 551.56 600.25 Td (which ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 588.25 Td (is ) Tj ET Q q 0 0 0 rg BT 45.17 588.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 98.20 588.25 Td (herein ) Tj ET Q q 0 0 0 rg BT 125.69 588.25 Td (by ) Tj ET Q q 0 0 0 rg BT 138.19 588.25 Td (reference ) Tj ET Q q 0 0 0 rg BT 177.87 588.25 Td (and ) Tj ET Q q 0 0 0 rg BT 194.81 588.25 Td (made ) Tj ET Q q 0 0 0 rg BT 218.96 588.25 Td (a ) Tj ET Q q 0 0 0 rg BT 225.90 588.25 Td (part ) Tj ET Q q 0 0 0 rg BT 243.95 588.25 Td (hereof ) Tj ET Q q 0 0 0 rg BT 271.99 588.25 Td (in ) Tj ET Q q 0 0 0 rg BT 282.26 588.25 Td (response ) Tj ET Q q 0 0 0 rg BT 319.75 588.25 Td (to ) Tj ET Q q 0 0 0 rg BT 330.03 588.25 Td (the ) Tj ET Q q 0 0 0 rg BT 344.75 588.25 Td (information ) Tj ET Q q 0 0 0 rg BT 394.46 588.25 Td (required ) Tj ET Q q 0 0 0 rg BT 430.28 588.25 Td (by ) Tj ET Q q 0 0 0 rg BT 442.78 588.25 Td (Item 1) Tj ET Q q 0 0 0 rg BT 468.23 588.25 Td (1.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 556.48 Td (Item 12.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 556.48 Td (SECURITY) Tj ET Q q 0 0 0 rg BT 146.31 556.48 Td ( OWNERSHIP) Tj ET Q q 0 0 0 rg BT 210.49 556.48 Td ( OF) Tj ET Q q 0 0 0 rg BT 226.50 556.48 Td ( CER) Tj ET Q q 0 0 0 rg BT 249.77 556.48 Td (T) Tj ET Q q 0 0 0 rg BT 255.69 556.48 Td (AIN BENEFICIAL) Tj ET Q q 0 0 0 rg BT 338.21 556.48 Td ( OWNERS ) Tj ET Q q 0 0 0 rg BT 387.11 556.48 Td (AND MANAGEMENT) Tj ET Q q 0 0 0 rg BT 486.65 556.48 Td ( ) Tj ET Q q 0 0 0 rg BT 488.60 556.48 Td (AND RELA) Tj ET Q q 0 0 0 rg BT 539.80 556.48 Td (TED) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 546.48 Td (ST) Tj ET Q q 0 0 0 rg BT 107.05 546.48 Td (OCKHOLDER MA) Tj ET Q q 0 0 0 rg BT 191.59 546.48 Td (TTERS.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 525.25 Td (Reference ) Tj ET Q q 0 0 0 rg BT 78.92 525.25 Td (is ) Tj ET Q q 0 0 0 rg BT 87.99 525.25 Td (made ) Tj ET Q q 0 0 0 rg BT 112.04 525.25 Td (to ) Tj ET Q q 0 0 0 rg BT 122.22 525.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 136.84 525.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 156.84 525.25 Td ( ) Tj ET Q q 0 0 0 rg BT 159.24 525.25 Td (Proxy ) Tj ET Q q 0 0 0 rg BT 185.53 525.25 Td (Statement ) Tj ET Q q 0 0 0 rg BT 227.92 525.25 Td (to ) Tj ET Q q 0 0 0 rg BT 238.09 525.25 Td (be ) Tj ET Q q 0 0 0 rg BT 249.93 525.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 270.65 525.25 Td (on ) Tj ET Q q 0 0 0 rg BT 283.05 525.25 Td (or ) Tj ET Q q 0 0 0 rg BT 293.78 525.25 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.40 525.25 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 361.90 525.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 381.90 525.25 Td ( ) Tj ET Q q 0 0 0 rg BT 384.29 525.25 Td (with ) Tj ET Q q 0 0 0 rg BT 404.47 525.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 435.19 525.25 Td (to ) Tj ET Q q 0 0 0 rg BT 445.36 525.25 Td (the ) Tj ET Q q 0 0 0 rg BT 459.98 525.25 Td (security ) Tj ET Q q 0 0 0 rg BT 494.03 525.25 Td (ownership ) Tj ET Q q 0 0 0 rg BT 538.09 525.25 Td (of ) Tj ET Q q 0 0 0 rg BT 548.82 525.25 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 513.25 Td (beneficial ) Tj ET Q q 0 0 0 rg BT 78.49 513.25 Td (owners ) Tj ET Q q 0 0 0 rg BT 110.44 513.25 Td (and ) Tj ET Q q 0 0 0 rg BT 127.94 513.25 Td (management, ) Tj ET Q q 0 0 0 rg BT 184.60 513.25 Td (which ) Tj ET Q q 0 0 0 rg BT 212.11 513.25 Td (is ) Tj ET Q q 0 0 0 rg BT 221.84 513.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 275.44 513.25 Td (herein ) Tj ET Q q 0 0 0 rg BT 303.50 513.25 Td (by ) Tj ET Q q 0 0 0 rg BT 316.56 513.25 Td (reference ) Tj ET Q q 0 0 0 rg BT 356.82 513.25 Td (and ) Tj ET Q q 0 0 0 rg BT 374.32 513.25 Td (made ) Tj ET Q q 0 0 0 rg BT 399.04 513.25 Td (a ) Tj ET Q q 0 0 0 rg BT 406.55 513.25 Td (part ) Tj ET Q q 0 0 0 rg BT 425.17 513.25 Td (hereof ) Tj ET Q q 0 0 0 rg BT 453.77 513.25 Td (in ) Tj ET Q q 0 0 0 rg BT 464.62 513.25 Td (response ) Tj ET Q q 0 0 0 rg BT 502.68 513.25 Td (to ) Tj ET Q q 0 0 0 rg BT 513.52 513.25 Td (the ) Tj ET Q q 0 0 0 rg BT 528.81 513.25 Td (information ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 501.25 Td (required ) Tj ET Q q 0 0 0 rg BT 71.82 501.25 Td (by ) Tj ET Q q 0 0 0 rg BT 84.32 501.25 Td (Item 12.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 481.48 Td (Item 13.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 481.48 Td (CER) Tj ET Q q 0 0 0 rg BT 115.76 481.48 Td (T) Tj ET Q q 0 0 0 rg BT 121.69 481.48 Td (AIN RELA) Tj ET Q q 0 0 0 rg BT 169.57 481.48 Td (TIONSHIPS ) Tj ET Q q 0 0 0 rg BT 225.98 481.48 Td (AND RELA) Tj ET Q q 0 0 0 rg BT 277.18 481.48 Td (TED ) Tj ET Q q 0 0 0 rg BT 300.06 481.48 Td (TRANSACTIONS.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 460.25 Td (Reference ) Tj ET Q q 0 0 0 rg BT 79.08 460.25 Td (is ) Tj ET Q q 0 0 0 rg BT 88.31 460.25 Td (made ) Tj ET Q q 0 0 0 rg BT 112.52 460.25 Td (to ) Tj ET Q q 0 0 0 rg BT 122.86 460.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 137.64 460.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 157.64 460.25 Td ( ) Tj ET Q q 0 0 0 rg BT 160.19 460.25 Td (Proxy ) Tj ET Q q 0 0 0 rg BT 186.64 460.25 Td (Statement ) Tj ET Q q 0 0 0 rg BT 229.19 460.25 Td (to ) Tj ET Q q 0 0 0 rg BT 239.53 460.25 Td (be ) Tj ET Q q 0 0 0 rg BT 251.53 460.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 272.41 460.25 Td (on ) Tj ET Q q 0 0 0 rg BT 284.97 460.25 Td (or ) Tj ET Q q 0 0 0 rg BT 295.86 460.25 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 320.63 460.25 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 364.29 460.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 384.29 460.25 Td ( ) Tj ET Q q 0 0 0 rg BT 386.85 460.25 Td (with ) Tj ET Q q 0 0 0 rg BT 407.19 460.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 438.06 460.25 Td (to ) Tj ET Q q 0 0 0 rg BT 448.40 460.25 Td (certain ) Tj ET Q q 0 0 0 rg BT 478.16 460.25 Td (relationships ) Tj ET Q q 0 0 0 rg BT 531.82 460.25 Td (and ) Tj ET Q q 0 0 0 rg BT 548.82 460.25 Td (related ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 448.25 Td (transactions, ) Tj ET Q q 0 0 0 rg BT 88.76 448.25 Td (which ) Tj ET Q q 0 0 0 rg BT 115.70 448.25 Td (is ) Tj ET Q q 0 0 0 rg BT 124.87 448.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 177.90 448.25 Td (herein ) Tj ET Q q 0 0 0 rg BT 205.39 448.25 Td (by ) Tj ET Q q 0 0 0 rg BT 217.89 448.25 Td (reference ) Tj ET Q q 0 0 0 rg BT 257.57 448.25 Td (and ) Tj ET Q q 0 0 0 rg BT 274.51 448.25 Td (made ) Tj ET Q q 0 0 0 rg BT 298.67 448.25 Td (a ) Tj ET Q q 0 0 0 rg BT 305.60 448.25 Td (part ) Tj ET Q q 0 0 0 rg BT 323.65 448.25 Td (hereof ) Tj ET Q q 0 0 0 rg BT 351.69 448.25 Td (in ) Tj ET Q q 0 0 0 rg BT 361.97 448.25 Td (response ) Tj ET Q q 0 0 0 rg BT 399.46 448.25 Td (to ) Tj ET Q q 0 0 0 rg BT 409.74 448.25 Td (the ) Tj ET Q q 0 0 0 rg BT 424.45 448.25 Td (information ) Tj ET Q q 0 0 0 rg BT 474.16 448.25 Td (required ) Tj ET Q q 0 0 0 rg BT 509.98 448.25 Td (by ) Tj ET Q q 0 0 0 rg BT 522.48 448.25 Td (Item 13.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 428.48 Td (Item 14.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 428.48 Td (AUDIT) Tj ET Q q 0 0 0 rg BT 127.05 428.48 Td (OR FEES.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 408.25 Td (Reference ) Tj ET Q q 0 0 0 rg BT 78.59 408.25 Td (is ) Tj ET Q q 0 0 0 rg BT 87.34 408.25 Td (made ) Tj ET Q q 0 0 0 rg BT 111.06 408.25 Td (to ) Tj ET Q q 0 0 0 rg BT 120.91 408.25 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 135.20 408.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 155.20 408.25 Td ( ) Tj ET Q q 0 0 0 rg BT 157.27 408.25 Td (Proxy ) Tj ET Q q 0 0 0 rg BT 183.24 408.25 Td (Statement ) Tj ET Q q 0 0 0 rg BT 225.30 408.25 Td (to ) Tj ET Q q 0 0 0 rg BT 235.15 408.25 Td (be ) Tj ET Q q 0 0 0 rg BT 246.66 408.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 267.06 408.25 Td (on ) Tj ET Q q 0 0 0 rg BT 279.13 408.25 Td (or ) Tj ET Q q 0 0 0 rg BT 289.53 408.25 Td (about ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 313.82 408.25 Td (March 22, ) Tj ET Q q 0 0 0 rg BT 356.99 408.25 Td (2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 376.99 408.25 Td ( ) Tj ET Q q 0 0 0 rg BT 379.06 408.25 Td (with ) Tj ET Q q 0 0 0 rg BT 398.91 408.25 Td (respect ) Tj ET Q q 0 0 0 rg BT 429.30 408.25 Td (to ) Tj ET Q q 0 0 0 rg BT 439.15 408.25 Td (auditor ) Tj ET Q q 0 0 0 rg BT 469.54 408.25 Td (fees, ) Tj ET Q q 0 0 0 rg BT 490.22 408.25 Td (which ) Tj ET Q q 0 0 0 rg BT 516.73 408.25 Td (is ) Tj ET Q q 0 0 0 rg BT 525.47 408.25 Td (incorporated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 396.25 Td (herein ) Tj ET Q q 0 0 0 rg BT 63.49 396.25 Td (by ) Tj ET Q q 0 0 0 rg BT 75.99 396.25 Td (reference ) Tj ET Q q 0 0 0 rg BT 115.67 396.25 Td (and ) Tj ET Q q 0 0 0 rg BT 132.61 396.25 Td (made ) Tj ET Q q 0 0 0 rg BT 156.76 396.25 Td (a ) Tj ET Q q 0 0 0 rg BT 163.70 396.25 Td (part ) Tj ET Q q 0 0 0 rg BT 181.75 396.25 Td (hereof ) Tj ET Q q 0 0 0 rg BT 209.78 396.25 Td (in ) Tj ET Q q 0 0 0 rg BT 220.06 396.25 Td (response ) Tj ET Q q 0 0 0 rg BT 257.55 396.25 Td (to ) Tj ET Q q 0 0 0 rg BT 267.83 396.25 Td (the ) Tj ET Q q 0 0 0 rg BT 282.55 396.25 Td (information ) Tj ET Q q 0 0 0 rg BT 332.26 396.25 Td (required ) Tj ET Q q 0 0 0 rg BT 368.08 396.25 Td (by ) Tj ET Q q 0 0 0 rg BT 380.58 396.25 Td (Item 14.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 372.25 Td (P) Tj ET Q q 0 0 0 rg BT 41.37 372.25 Td (AR) Tj ET Q q 0 0 0 rg BT 55.46 372.25 Td (T) Tj ET Q q 0 0 0 rg BT 61.95 372.25 Td ( IV) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 352.48 Td (Item 15.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 352.48 Td (EXHIBITS and FINANCIAL) Tj ET Q q 0 0 0 rg BT 220.60 352.48 Td ( ST) Tj ET Q q 0 0 0 rg BT 234.58 352.48 Td (A) Tj ET Q q 0 0 0 rg BT 241.06 352.48 Td (TEMENT) Tj ET Q q 0 0 0 rg BT 284.22 352.48 Td ( SCHEDULE.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 48.45 336.25 Td (\(a\) ) Tj ET Q BT /F1 10.00 Tf ET 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 518.5 290.75 m 576.5 290.75 l s BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 295.00 Td ( ) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 61.00 295.00 Td ( ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 538.75 302.83 Td (Page) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 532.85 294.83 Td (Number) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 281.32 Td (1.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 61.00 281.32 Td (Consolidated Financial Statements) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 106 265.9833984375 m 254.0322265625 265.9833984375 l s q 0 0 1 rg BT 106.00 267.32 Td (Consolidated ) Tj ET Q q 0 0 1 rg BT 161.27 267.32 Td (Statements ) Tj ET Q q 0 0 1 rg BT 207.66 267.32 Td (of ) Tj ET Q q 0 0 1 rg BT 218.49 267.32 Td (Earnings) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 254.0322265625 265.9833984375 m 368.7197265625 265.9833984375 l s q 0 0 1 rg BT 254.03 267.32 Td ( ) Tj ET Q q 0 0 1 rg BT 256.53 267.32 Td (and ) Tj ET Q q 0 0 1 rg BT 273.47 267.32 Td (Comprehensive ) Tj ET Q q 0 0 1 rg BT 338.73 267.32 Td (Income) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 106 251.9833984375 m 222.083984375 251.9833984375 l s q 0 0 1 rg BT 106.00 253.32 Td (Consolidated ) Tj ET Q q 0 0 1 rg BT 161.27 253.32 Td (Balance ) Tj ET Q q 0 0 1 rg BT 195.98 253.32 Td (Sheets) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 106 237.9833984375 m 265.4384765625 237.9833984375 l s q 0 0 1 rg BT 106.00 239.32 Td (Consolidated ) Tj ET Q q 0 0 1 rg BT 161.27 239.32 Td (Statements ) Tj ET Q q 0 0 1 rg BT 207.66 239.32 Td (of ) Tj ET Q q 0 0 1 rg BT 218.49 239.32 Td (Cash ) Tj ET Q q 0 0 1 rg BT 240.99 239.32 Td (Flows) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 106 223.9833984375 m 280.9755859375 223.9833984375 l s q 0 0 1 rg BT 106.00 225.32 Td (Notes ) Tj ET Q q 0 0 1 rg BT 131.83 225.32 Td (to ) Tj ET Q q 0 0 1 rg BT 142.11 225.32 Td (Consolidated ) Tj ET Q q 0 0 1 rg BT 197.38 225.32 Td (Financial ) Tj ET Q q 0 0 1 rg BT 237.09 225.32 Td (Statements) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 106 209.9833984375 m 339.8427734375 209.9833984375 l s q 0 0 1 rg BT 106.00 211.32 Td (Report ) Tj ET Q q 0 0 1 rg BT 135.72 211.32 Td (of ) Tj ET Q q 0 0 1 rg BT 146.55 211.32 Td (Independent ) Tj ET Q q 0 0 1 rg BT 198.47 211.32 Td (Registered ) Tj ET Q q 0 0 1 rg BT 243.73 211.32 Td (Public ) Tj ET Q q 0 0 1 rg BT 271.24 211.32 Td (Accounting ) Tj ET Q q 0 0 1 rg BT 320.39 211.32 Td (Firm) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL q 0 0 0 rg BT 39.00 192.42 Td (All ) Tj ET Q q 0 0 0 rg BT 53.38 192.42 Td (other ) Tj ET Q q 0 0 0 rg BT 75.52 192.42 Td (schedules ) Tj ET Q q 0 0 0 rg BT 116.00 192.42 Td (not ) Tj ET Q q 0 0 0 rg BT 130.37 192.42 Td (included ) Tj ET Q q 0 0 0 rg BT 166.40 192.42 Td (with ) Tj ET Q q 0 0 0 rg BT 185.78 192.42 Td (this ) Tj ET Q q 0 0 0 rg BT 201.83 192.42 Td (additional ) Tj ET Q q 0 0 0 rg BT 243.42 192.42 Td (financial ) Tj ET Q q 0 0 0 rg BT 279.99 192.42 Td (data ) Tj ET Q q 0 0 0 rg BT 298.25 192.42 Td (are ) Tj ET Q q 0 0 0 rg BT 312.05 192.42 Td (omitted ) Tj ET Q q 0 0 0 rg BT 344.20 192.42 Td (because ) Tj ET Q q 0 0 0 rg BT 377.45 192.42 Td (they ) Tj ET Q q 0 0 0 rg BT 396.26 192.42 Td (are ) Tj ET Q q 0 0 0 rg BT 410.07 192.42 Td (not ) Tj ET Q q 0 0 0 rg BT 424.44 192.42 Td (applicable ) Tj ET Q q 0 0 0 rg BT 467.13 192.42 Td (or ) Tj ET Q q 0 0 0 rg BT 477.06 192.42 Td (the ) Tj ET Q q 0 0 0 rg BT 490.87 192.42 Td (required ) Tj ET Q q 0 0 0 rg BT 525.79 192.42 Td (information ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 182.42 Td (is ) Tj ET Q q 0 0 0 rg BT 48.17 182.42 Td (included ) Tj ET Q q 0 0 0 rg BT 85.10 182.42 Td (in ) Tj ET Q q 0 0 0 rg BT 95.38 182.42 Td (the ) Tj ET Q q 0 0 0 rg BT 110.10 182.42 Td (financial ) Tj ET Q q 0 0 0 rg BT 147.58 182.42 Td (statements ) Tj ET Q q 0 0 0 rg BT 192.29 182.42 Td (or ) Tj ET Q q 0 0 0 rg BT 203.12 182.42 Td (notes ) Tj ET Q q 0 0 0 rg BT 226.73 182.42 Td (thereto.) 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Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 39.00 119.48 Td (Item 16.) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 95.00 119.48 Td (FORM 10-K SUMMAR) Tj ET Q q 0 0 0 rg BT 197.41 119.48 Td (Y) Tj ET Q q 0 0 0 rg BT 203.71 119.48 Td (.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 99.25 Td (None.) 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CALDARELLA) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 445.27 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 445.27 Td (Senior ) Tj ET Q q 0 0 0 rg BT 291.52 445.27 Td (V) Tj ET Q q 0 0 0 rg BT 298.35 445.27 Td (ice President and Corporate Controller) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 445.27 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 445.27 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 431.17 Td (\(Joseph C. Caldarella\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 431.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 431.17 Td (\(Principal ) Tj ET Q q 0 0 0 rg BT 304.66 431.17 Td (Accounting Of) Tj ET Q q 0 0 0 rg BT 364.00 431.17 Td (ficer\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 431.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 413.17 Td (/s/ PETER J. ) Tj ET Q q 0 0 0 rg BT 92.62 413.17 Td (ARDUINI) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 413.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 413.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 413.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 413.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 399.17 Td (\(Peter J. ) Tj ET Q q 0 0 0 rg BT 73.99 399.17 Td (Arduini\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 399.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 399.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 381.17 Td (/s/ ROBER) Tj ET Q q 0 0 0 rg BT 83.99 381.17 Td (T) Tj ET Q q 0 0 0 rg BT 89.71 381.17 Td ( J. BER) Tj ET Q q 0 0 0 rg BT 120.15 381.17 Td (T) Tj ET Q q 0 0 0 rg BT 125.87 381.17 Td (OLINI) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 381.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 381.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 367.17 Td (\(Robert J. Bertolini\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 349.17 Td (/s/ MA) Tj ET Q q 0 0 0 rg BT 66.51 349.17 Td (TTHEW) Tj ET Q q 0 0 0 rg BT 100.85 349.17 Td ( ) Tj ET Q q 0 0 0 rg BT 103.17 349.17 Td (W) Tj ET Q q 0 0 0 rg BT 112.06 349.17 Td (. EMMENS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 349.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 349.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 335.17 Td (\(Matthew ) Tj ET Q q 0 0 0 rg BT 80.29 335.17 Td (W) Tj ET Q q 0 0 0 rg BT 89.18 335.17 Td (. Emmens\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 317.17 Td (/s/ MICHAEL) Tj ET Q q 0 0 0 rg BT 96.31 317.17 Td ( GROBSTEIN) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 317.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 317.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 317.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 317.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 303.17 Td (\(Michael Grobstein\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 303.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 303.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 285.17 Td (/s/ ) Tj ET Q q 0 0 0 rg BT 50.67 285.17 Td (ALAN J. LACY) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 285.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 285.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 285.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 285.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 271.17 Td (\(Alan J. Lacy\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 271.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 271.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 253.17 Td (/s/ DINESH C. P) Tj ET Q q 0 0 0 rg BT 106.89 253.17 Td (ALIW) Tj ET Q q 0 0 0 rg BT 131.97 253.17 Td (AL) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 253.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 253.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 253.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 239.17 Td (\(Dinesh C. Paliwal\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 221.17 Td (/s/ ) Tj ET Q q 0 0 0 rg BT 50.86 221.17 Td (THEODORE R. SAMUELS) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 221.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 221.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 207.17 Td (\(Theodore R. Samuels\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 189.17 Td (/s/ ) Tj ET Q q 0 0 0 rg BT 50.86 189.17 Td (VICKI L. SA) Tj ET Q q 0 0 0 rg BT 104.38 189.17 Td (T) Tj ET Q q 0 0 0 rg BT 109.84 189.17 Td (O, PH.D.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 189.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 189.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 189.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 189.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 175.17 Td (\(V) Tj ET Q q 0 0 0 rg BT 49.25 175.17 Td (icki L. Sato, Ph.D.\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 175.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 175.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 157.17 Td (/s/ GERALD L. ST) Tj ET Q q 0 0 0 rg BT 116.69 157.17 Td (ORCH) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 157.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 157.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 157.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 157.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 143.17 Td (\(Gerald L. Storch\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 143.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 143.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 125.17 Td (/s/ KAREN H. ) Tj ET Q q 0 0 0 rg BT 100.02 125.17 Td (VOUSDEN, PH.D.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 125.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 263.00 125.17 Td (Director) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 125.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 470.70 125.17 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 39.00 111.17 Td (\(Karen H. ) Tj ET Q q 0 0 0 rg BT 81.30 111.17 Td (V) Tj ET Q q 0 0 0 rg BT 87.23 111.17 Td (ousden, Ph.D.\)) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 259.00 111.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 459.00 111.17 Td ( ) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 217 0 obj <> endobj 218 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (108) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 22.50 750.60 Td (SUMMAR) Tj ET Q q 0 0 0 rg BT 59.10 750.60 Td (Y) Tj ET Q q 0 0 0 rg BT 64.58 750.60 Td ( OF) Tj ET Q q 0 0 0 rg BT 77.39 750.60 Td ( ) Tj ET Q q 0 0 0 rg BT 78.95 750.60 Td (ABBREVIA) Tj ET Q q 0 0 0 rg BT 120.59 750.60 Td (TED ) Tj ET Q q 0 0 0 rg BT 138.89 750.60 Td (TERMS) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 22.50 736.80 Td (Bristol-Myers Squibb Company may be referred to as Bristol-Myers Squibb, BMS, the Company) Tj ET Q q 0 0 0 rg BT 372.38 736.80 Td (, we, our or us in this ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 450.63 736.80 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 468.63 736.80 Td ( Form 10-K. ) Tj ET Q q 0 0 0 rg BT 515.47 736.80 Td (Throughout this ) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 22.50 726.00 Td (2017) Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 40.50 726.00 Td ( Form 10-K we have used terms which are defined below:) Tj ET Q 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 715.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 715.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 715.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 715.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 691.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 691.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 691.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 691.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 667.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 667.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 667.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 667.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 643.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 643.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 643.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 643.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 619.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 619.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 619.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 619.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 595.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 595.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 595.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 595.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 571.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 571.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 571.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 571.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 547.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 547.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 547.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 547.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 523.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 523.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 523.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 523.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 499.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 499.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 499.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 499.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 475.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 475.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 475.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 475.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 443.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 443.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 443.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 443.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 419.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 419.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 419.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 419.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 395.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 395.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 395.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 395.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 371.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 371.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 371.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 371.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 347.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 347.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 347.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 347.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 315.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 315.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 315.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 315.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 291.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 291.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 291.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 291.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 267.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 267.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 267.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 267.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 243.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 243.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 243.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 243.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 219.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 219.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 219.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 219.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 195.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 195.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 195.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 195.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 171.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 171.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 171.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 171.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 147.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 147.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 147.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 147.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 123.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 123.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 123.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 123.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 99.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 99.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 99.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 99.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 75.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 75.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 75.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 75.50 209.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 22.00 51.50 60.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 82.00 51.50 245.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 327.00 51.50 53.00 -12.00 re f /GS0 gs 0.8 0.9333333333333333 1 rg /GS0 gs 380.00 51.50 209.00 -12.00 re f /GS0 gs 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 715.5 m 22 703.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 715.5 m 82 715.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 715.5 m 327 703.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 82 715.5 m 327 715.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 715.5 m 380 715.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 715.5 m 589 703.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380 715.5 m 589 715.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 703.5 m 22 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 703.5 m 327 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 703.5 m 589 691.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 691.5 m 22 679.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 691.5 m 327 679.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 691.5 m 589 679.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 679.5 m 22 667.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 679.5 m 327 667.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 679.5 m 589 667.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 667.5 m 22 655.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 667.5 m 327 655.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 667.5 m 589 655.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 655.5 m 22 643.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 655.5 m 327 643.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 655.5 m 589 643.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 643.5 m 22 631.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 643.5 m 327 631.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 643.5 m 589 631.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 631.5 m 22 619.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 631.5 m 327 619.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 631.5 m 589 619.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 619.5 m 22 607.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 619.5 m 327 607.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 619.5 m 589 607.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 607.5 m 22 595.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 607.5 m 327 595.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 607.5 m 589 595.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 595.5 m 22 583.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 595.5 m 327 583.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 595.5 m 589 583.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 583.5 m 22 571.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 583.5 m 327 571.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 583.5 m 589 571.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 571.5 m 22 559.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 571.5 m 327 559.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 571.5 m 589 559.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 559.5 m 22 547.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 559.5 m 327 547.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 559.5 m 589 547.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 547.5 m 22 535.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 547.5 m 327 535.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 547.5 m 589 535.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 535.5 m 22 523.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 535.5 m 327 523.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 535.5 m 589 523.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 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327 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 291.5 m 589 279.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 279.5 m 22 267.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 279.5 m 327 267.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 279.5 m 589 267.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 267.5 m 22 255.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 267.5 m 327 255.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 267.5 m 589 255.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 255.5 m 22 243.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 255.5 m 327 243.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 255.5 m 589 243.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 243.5 m 22 231.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 243.5 m 327 231.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 243.5 m 327 231.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 243.5 m 589 231.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 231.5 m 22 219.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 231.5 m 327 219.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 231.5 m 327 219.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 231.5 m 589 219.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 219.5 m 22 207.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 219.5 m 327 207.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 219.5 m 589 207.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 207.5 m 22 195.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 207.5 m 327 195.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 207.5 m 589 195.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 195.5 m 22 183.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 195.5 m 327 183.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 195.5 m 589 183.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 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1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 135.5 m 589 123.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 123.5 m 22 111.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 123.5 m 327 111.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 123.5 m 589 111.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 111.5 m 22 99.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 111.5 m 327 99.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 111.5 m 589 99.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 99.5 m 22 87.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 99.5 m 327 87.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 99.5 m 589 87.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 87.5 m 22 75.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 87.5 m 327 75.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 87.5 m 589 75.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 75.5 m 22 63.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 75.5 m 327 63.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 75.5 m 589 63.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 63.5 m 22 51.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 63.5 m 327 51.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 63.5 m 589 51.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 51.5 m 22 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 22 39.5 m 82 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 82 39.5 m 327 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 51.5 m 327 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 327 39.5 m 380 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 589 51.5 m 589 39.5 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 380 39.5 m 589 39.5 l s BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 707.77 Td (2017 Form 10-K) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 707.77 Td (Annual Report on Form 10-K for the fiscal year ended December 31, 2017) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 707.77 Td (LIBOR) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 707.77 Td (London Interbank Of) Tj ET Q q 0 0 0 rg BT 445.32 707.77 Td (fered Rate) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 695.77 Td (AbbV) Tj ET Q q 0 0 0 rg BT 42.37 695.77 Td (ie) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 695.77 Td (AbbV) Tj ET Q q 0 0 0 rg BT 102.37 695.77 Td (ie Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 695.77 Td (Lilly) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 695.77 Td (Eli Lilly and Company) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 683.77 Td (ALL) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 683.77 Td (acute lymphoblastic leukemia) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 683.77 Td (LOE) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 683.77 Td (loss of exclusivity) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 671.77 Td (Amira) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 671.77 Td (Amira Pharmaceuticals, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 671.77 Td (MAA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 671.77 Td (Marketing ) Tj ET Q q 0 0 0 rg BT 414.97 671.77 Td (Authorization ) Tj ET Q q 0 0 0 rg BT 457.52 671.77 Td (Application) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 659.77 Td (Amylin) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 659.77 Td (Amylin Pharmaceuticals, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 659.77 Td (MCOs) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 659.77 Td (Managed Care Or) Tj ET Q q 0 0 0 rg BT 435.44 659.77 Td (ganizations) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 647.77 Td (aNDA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 647.77 Td (abbreviated New Drug ) Tj ET Q q 0 0 0 rg BT 153.54 647.77 Td (Application) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 647.77 Td (mCRC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 647.77 Td (metastatic colorectal cancer) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 635.77 Td (API) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 635.77 Td (active pharmaceutical ingredient) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 635.77 Td (MDL) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 635.77 Td (multi-district litigation) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 623.77 Td (ASEAN) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 623.77 Td (Association of Southeast ) Tj ET Q q 0 0 0 rg BT 159.73 623.77 Td (Asian Nations) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 623.77 Td (Mead Johnson) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 623.77 Td (Mead Johnson Nutrition Company) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 611.77 Td (AstraZeneca) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 611.77 Td (AstraZeneca PLC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 611.77 Td (Merck) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 611.77 Td (Merck & Co., Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 599.77 Td (auto-HSCT) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 599.77 Td (autologous hematopoietic stem cell transplantation) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 599.77 Td (MF) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 599.77 Td (myelofibrosis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 587.77 Td (Biogen) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 587.77 Td (Biogen, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 587.77 Td (MPM) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 587.77 Td (malignant pleural mesothelioma) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 575.77 Td (BLA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 575.77 Td (Biologics License ) Tj ET Q q 0 0 0 rg BT 139.38 575.77 Td (Application) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 575.77 Td (MSI-H) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 575.77 Td (high microsatellite instability) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 563.77 Td (Cardioxyl) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 563.77 Td (Cardioxyl Pharmaceuticals, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 563.77 Td (mUC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 563.77 Td (metastatic urothelial carcinoma) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 551.77 Td (CERCLA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 551.77 Td (U.S. Comprehensive Environmental Response, Compensation and Liability ) Tj ET Q q 0 0 0 rg BT 309.97 551.77 Td (Act) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 551.77 Td (NA) Tj ET Q q 0 0 0 rg BT 339.71 551.77 Td (V) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 551.77 Td (net asset value) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 539.77 Td (cGMP) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 539.77 Td (current Good Manufacturing Practices) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 539.77 Td (NDA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 539.77 Td (New Drug ) Tj ET Q q 0 0 0 rg BT 415.18 539.77 Td (Application) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 527.77 Td (cHL) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 527.77 Td (classical Hodgkin lymphoma) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 527.77 Td (Nitto Denko) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 527.77 Td (Nitto Denko Corporation) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 515.77 Td (CHMP) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 515.77 Td (Committee for Medicinal Products for Human Use) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 515.77 Td (NKT) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 515.77 Td (natural killer ) Tj ET Q q 0 0 0 rg BT 422.30 515.77 Td (T) Tj ET Q q 0 0 0 rg BT 426.68 515.77 Td ( cells) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 503.77 Td (CML) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 503.77 Td (chronic myeloid leukemia) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 503.77 Td (Novartis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 503.77 Td (Novartis Pharmaceutical Corporation) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 491.77 Td (Cormorant) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 491.77 Td (Cormorant Pharmaceuticals) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 491.77 Td (NSCLC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 491.77 Td (non-small cell lung cancer) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 479.77 Td (CPPIB) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 479.77 Td (CPPIB Credit Europe S.A.R.L., a Luxembour) Tj ET Q q 0 0 0 rg BT 220.09 479.77 Td (g private limited liability company) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 479.77 Td (NV) Tj ET Q q 0 0 0 rg BT 339.71 479.77 Td (AF) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 479.77 Td (nonvalvular atrial fibrillation) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 467.77 Td (CSF1R) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 467.77 Td (colony stimulating factor 1 receptor) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 467.77 Td (OCI) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 467.77 Td (Other Comprehensive Income) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 451.77 Td (CytomX) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 451.77 Td (CytomX ) Tj ET Q q 0 0 0 rg BT 111.77 451.77 Td (Therapeutics, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 451.77 Td (OIG) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 455.47 Td (Of) Tj ET Q q 0 0 0 rg BT 390.24 455.47 Td (fice of Inspector General of the U.S. Dept. of Health and Human) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 448.07 Td (Services) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 435.77 Td (dMMR) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 435.77 Td (DNA) Tj ET Q q 0 0 0 rg BT 100.33 435.77 Td ( mismatch repair deficient) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 435.77 Td (Ono) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 435.77 Td (Ono Pharmaceutical Co., Ltd.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 423.77 Td (DSA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 423.77 Td (Distribution Services ) Tj ET Q q 0 0 0 rg BT 148.84 423.77 Td (Agreement) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 423.77 Td (OTC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 423.77 Td (Over) Tj ET Q q 0 0 0 rg BT 397.22 423.77 Td (-the-counter) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 411.77 Td (EC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 411.77 Td (European Commission) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 411.77 Td (Otsuka) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 411.77 Td (Otsuka Pharmaceutical Co., Ltd.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 399.77 Td (EMA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 399.77 Td (European Medicines ) Tj ET Q q 0 0 0 rg BT 147.18 399.77 Td (Agency) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 399.77 Td (P) Tj ET Q q 0 0 0 rg BT 333.28 399.77 Td (AD) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 399.77 Td (Protein/Peptidyl ) Tj ET Q q 0 0 0 rg BT 432.25 399.77 Td (Ar) Tj ET Q q 0 0 0 rg BT 439.79 399.77 Td (ginine Deiminase) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 387.77 Td (EPO) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 387.77 Td (European Patent Of) Tj ET Q q 0 0 0 rg BT 142.79 387.77 Td (fice) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 387.77 Td (Padlock) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 387.77 Td (Padlock ) Tj ET Q q 0 0 0 rg BT 408.12 387.77 Td (Therapeutics, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 375.77 Td (EPS) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 375.77 Td (earnings per share) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 375.77 Td (PBMs) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 375.77 Td (Pharmacy Benefit Managers) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 363.77 Td (ERISA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 363.77 Td (Employee Retirement Income Security ) Tj ET Q q 0 0 0 rg BT 201.43 363.77 Td (Act of 1974) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 363.77 Td (PD-1) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 363.77 Td (programmed death receptor) Tj ET Q q 0 0 0 rg BT 464.20 363.77 Td (-1) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 351.77 Td (EU) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 351.77 Td (European Union) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 351.77 Td (PDMA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 351.77 Td (Prescription Drug Marketing ) Tj ET Q q 0 0 0 rg BT 469.64 351.77 Td (Act) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 339.77 Td (F) Tj ET Q q 0 0 0 rg BT 28.34 339.77 Td (ASB) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 339.77 Td (Financial ) Tj ET Q q 0 0 0 rg BT 113.68 339.77 Td (Accounting Standards Board) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 339.77 Td (Pfizer) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 339.77 Td (Pfizer) Tj ET Q q 0 0 0 rg BT 400.02 339.77 Td (, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 323.77 Td (FCP) Tj ET Q q 0 0 0 rg BT 37.33 323.77 Td (A) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 323.77 Td (Foreign Corrupt Practices ) Tj ET Q q 0 0 0 rg BT 162.60 323.77 Td (Act) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 323.77 Td (PHRMA) Tj ET Q q 0 0 0 rg BT 355.61 323.77 Td ( Code) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 327.47 Td (Pharmaceutical Research and Manufacturers of ) Tj ET Q q 0 0 0 rg BT 524.27 327.47 Td (America’) Tj ET Q q 0 0 0 rg BT 551.81 327.47 Td (s) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 320.07 Td (Professional Practices Code) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 307.77 Td (FDA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 307.77 Td (U.S. Food and Drug ) Tj ET Q q 0 0 0 rg BT 145.96 307.77 Td (Administration) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 307.77 Td (Promedior) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 307.77 Td (Promedior) Tj ET Q q 0 0 0 rg BT 413.59 307.77 Td (, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 295.77 Td (Five Prime) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 295.77 Td (Five Prime ) Tj ET Q q 0 0 0 rg BT 118.97 295.77 Td (Therapeutics, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 295.77 Td (PRP) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 295.77 Td (potentially responsible party) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 283.77 Td (Flexus) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 283.77 Td (Flexus Biosciences, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 283.77 Td (PSA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 283.77 Td (prostate-specific antigen) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 271.77 Td (F-Star) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 271.77 Td (F-Star ) Tj ET Q q 0 0 0 rg BT 104.65 271.77 Td (Alpha Ltd.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 271.77 Td (PsiOxus) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 271.77 Td (PsiOxus ) Tj ET Q q 0 0 0 rg BT 408.96 271.77 Td (Therapeutics, Ltd.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 259.77 Td (GAAP) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 259.77 Td (U.S. generally accepted accounting principles) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 259.77 Td (PVNS) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 259.77 Td (pigmented vilonodular synovitis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 247.77 Td (GBM) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 247.77 Td (glioblastoma multiforme) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 247.77 Td (R&D) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 247.77 Td (Research and Development) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 235.77 Td (GDD) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 235.77 Td (Genetically Defined Diseases) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 235.77 Td (RA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 235.77 Td (rheumatoid arthritis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 223.77 Td (Gilead) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 223.77 Td (Gilead Sciences, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 223.77 Td (RCC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 223.77 Td (renal cell carcinoma) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 211.77 Td (GTN) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 211.77 Td (gross-to-net) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 211.77 Td (RDP) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 211.77 Td (regulatory data protection) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 199.62 Td (Halozyme) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 199.62 Td (Halozyme ) Tj ET Q q 0 0 0 rg BT 116.63 199.62 Td (Therapeutics, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 199.77 Td (Reckitt) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 199.77 Td (Reckitt Benckiser Group plc) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 187.77 Td (HCC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 187.77 Td (Hepatocellular carcinoma) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 187.77 Td (Roche) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 187.77 Td (Roche Holding ) Tj ET Q q 0 0 0 rg BT 429.16 187.77 Td (AG) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 175.77 Td (HCV) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 175.77 Td (hepatitis C virus) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 175.77 Td (Sanofi) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 175.77 Td (Sanofi S.A.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 163.77 Td (HIV) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 163.77 Td (human immunodeficiency virus) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 163.77 Td (sBLA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 163.77 Td (supplemental Biologics License ) Tj ET Q q 0 0 0 rg BT 478.68 163.77 Td (Application) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 151.77 Td (HNC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 151.77 Td (head and neck cancer) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 151.77 Td (SCCHN) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 151.77 Td (squamous cell carcinoma of the head and neck) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 139.77 Td (HPV) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 139.77 Td (human papillomavirus) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 139.77 Td (SCLC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 139.77 Td (small cell lung cancer) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 127.77 Td (HR 3590) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 127.77 Td (The Patient Protection and ) Tj ET Q q 0 0 0 rg BT 164.86 127.77 Td (Af) Tj ET Q q 0 0 0 rg BT 172.39 127.77 Td (fordable Care ) Tj ET Q q 0 0 0 rg BT 214.45 127.77 Td (Act) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 127.77 Td (SEC) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 127.77 Td (U.S. Securities and Exchange Commission) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 115.77 Td (IFM) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 115.77 Td (IFM ) Tj ET Q q 0 0 0 rg BT 99.44 115.77 Td (Therapeutics, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 115.77 Td (SK Biotek) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 115.77 Td (SK Biotek Co., Ltd.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 103.77 Td (ImClone) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 103.77 Td (ImClone Systems Incorporated) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 103.77 Td (the 2012 Plan) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 103.77 Td (The 2012 Stock ) Tj ET Q q 0 0 0 rg BT 431.01 103.77 Td (A) Tj ET Q q 0 0 0 rg BT 435.81 103.77 Td (ward and Incentive Plan) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 91.77 Td (IO) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 91.77 Td (Immuno-Oncology) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 91.77 Td (U.S.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 91.77 Td (United States) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 79.77 Td (IPF) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 79.77 Td (idiopathic pulmonary fibrosis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 79.77 Td (UK) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 79.77 Td (United Kingdom) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 67.77 Td (iPierian) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 67.77 Td (iPierian, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 67.77 Td (V) Tj ET Q q 0 0 0 rg BT 334.43 67.77 Td (aleant) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 67.77 Td (V) Tj ET Q q 0 0 0 rg BT 387.43 67.77 Td (aleant Pharmaceuticals International, Inc.) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 55.77 Td (IPRD) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 55.77 Td (in-process research and development) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 55.77 Td (VTE) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 55.77 Td (venous thromboembolic) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 24.50 43.77 Td (JIA) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 84.50 43.77 Td (Juvenile Idiopathic ) Tj ET Q q 0 0 0 rg BT 142.66 43.77 Td (Arthritis) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 329.50 43.77 Td (WT) Tj ET Q q 0 0 0 rg BT 340.94 43.77 Td (O) Tj ET Q BT /F1 7.40 Tf ET q 0 0 0 rg BT 382.50 43.77 Td (W) Tj ET Q q 0 0 0 rg BT 388.89 43.77 Td (orld ) Tj ET Q q 0 0 0 rg BT 402.53 43.77 Td (T) Tj ET Q q 0 0 0 rg BT 406.79 43.77 Td (rade Or) Tj ET Q q 0 0 0 rg BT 429.05 43.77 Td (ganization) Tj ET Q BT /F1 10.00 Tf ET endstream endobj 219 0 obj <> endobj 220 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.50 24.60 Td (109) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 36.00 737.25 Td (EXHIBIT) Tj ET Q q 0 0 0 rg BT 78.61 737.25 Td ( INDEX) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 720.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.60 720.25 Td (Exhibits ) Tj ET Q q 0 0 0 rg BT 90.98 720.25 Td (listed ) Tj ET Q q 0 0 0 rg BT 115.69 720.25 Td (below ) Tj ET Q q 0 0 0 rg BT 143.18 720.25 Td (are ) Tj ET Q q 0 0 0 rg BT 158.43 720.25 Td (identified ) Tj ET Q q 0 0 0 rg BT 199.80 720.25 Td (by ) Tj ET Q q 0 0 0 rg BT 212.85 720.25 Td (numbers ) Tj ET Q q 0 0 0 rg BT 250.34 720.25 Td (corresponding ) Tj ET Q q 0 0 0 rg BT 310.59 720.25 Td (to ) Tj ET Q q 0 0 0 rg BT 321.42 720.25 Td (the ) Tj ET Q q 0 0 0 rg BT 336.69 720.25 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 368.96 720.25 Td (T) Tj ET Q q 0 0 0 rg BT 374.37 720.25 Td (able ) Tj ET Q q 0 0 0 rg BT 394.07 720.25 Td (of ) Tj ET Q q 0 0 0 rg BT 405.45 720.25 Td (Item 601 ) Tj ET Q q 0 0 0 rg BT 444.32 720.25 Td (of ) Tj ET Q q 0 0 0 rg BT 455.70 720.25 Td (Regulation ) Tj ET Q q 0 0 0 rg BT 502.63 720.25 Td (S-K. ) Tj ET Q q 0 0 0 rg BT 524.07 720.25 Td (The ) Tj ET Q q 0 0 0 rg BT 542.67 720.25 Td (Exhibits ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 708.25 Td (designated ) Tj ET Q q 0 0 0 rg BT 81.08 708.25 Td (by ) Tj ET Q q 0 0 0 rg BT 93.40 708.25 Td (the ) Tj ET Q q 0 0 0 rg BT 107.94 708.25 Td (symbol ) Tj ET Q q 0 0 0 rg BT 139.71 708.25 Td (‡‡ ) Tj ET Q q 0 0 0 rg BT 152.03 708.25 Td (are ) Tj ET Q q 0 0 0 rg BT 166.55 708.25 Td (management ) Tj ET Q q 0 0 0 rg BT 219.96 708.25 Td (contracts ) Tj ET Q q 0 0 0 rg BT 258.37 708.25 Td (or ) Tj ET Q q 0 0 0 rg BT 269.02 708.25 Td (compensatory ) Tj ET Q q 0 0 0 rg BT 327.44 708.25 Td (plans ) Tj ET Q q 0 0 0 rg BT 350.86 708.25 Td (or ) Tj ET Q q 0 0 0 rg BT 361.51 708.25 Td (arrangements ) Tj ET Q q 0 0 0 rg BT 417.69 708.25 Td (required ) Tj ET Q q 0 0 0 rg BT 453.33 708.25 Td (to ) Tj ET Q q 0 0 0 rg BT 463.43 708.25 Td (be ) Tj ET Q q 0 0 0 rg BT 475.18 708.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 495.83 708.25 Td (pursuant ) Tj ET Q q 0 0 0 rg BT 532.59 708.25 Td (to ) Tj ET Q q 0 0 0 rg BT 542.68 708.25 Td (Item 15. ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 696.25 Td (The ) Tj ET Q q 0 0 0 rg BT 54.33 696.25 Td (symbol ) Tj ET Q q 0 0 0 rg BT 86.56 696.25 Td (‡ ) Tj ET Q q 0 0 0 rg BT 94.34 696.25 Td (in ) Tj ET Q q 0 0 0 rg BT 104.91 696.25 Td (the ) Tj ET Q q 0 0 0 rg BT 119.91 696.25 Td (Page ) Tj ET Q q 0 0 0 rg BT 142.13 696.25 Td (column ) Tj ET Q q 0 0 0 rg BT 174.91 696.25 Td (indicates ) Tj ET Q q 0 0 0 rg BT 213.23 696.25 Td (that ) Tj ET Q q 0 0 0 rg BT 231.01 696.25 Td (the ) Tj ET Q q 0 0 0 rg BT 246.01 696.25 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 278.24 696.25 Td (has ) Tj ET Q q 0 0 0 rg BT 294.35 696.25 Td (been ) Tj ET Q q 0 0 0 rg BT 316.01 696.25 Td (previously ) Tj ET Q q 0 0 0 rg BT 361.01 696.25 Td (filed ) Tj ET Q q 0 0 0 rg BT 382.12 696.25 Td (with ) Tj ET Q q 0 0 0 rg BT 402.68 696.25 Td (the ) Tj ET Q q 0 0 0 rg BT 417.68 696.25 Td (Commission ) Tj ET Q q 0 0 0 rg BT 471.03 696.25 Td (and ) Tj ET Q q 0 0 0 rg BT 488.25 696.25 Td (is ) Tj ET Q q 0 0 0 rg BT 497.70 696.25 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 551.02 696.25 Td (herein ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 36.00 684.25 Td (by ) Tj ET Q q 0 0 0 rg BT 48.50 684.25 Td (reference. ) Tj ET Q q 0 0 0 rg BT 90.68 684.25 Td (Unless ) Tj ET Q q 0 0 0 rg BT 120.40 684.25 Td (otherwise ) Tj ET Q q 0 0 0 rg BT 161.78 684.25 Td (indicated, ) Tj ET Q q 0 0 0 rg BT 203.43 684.25 Td (all ) Tj ET Q q 0 0 0 rg BT 215.93 684.25 Td (Exhibits ) Tj ET Q q 0 0 0 rg BT 251.76 684.25 Td (are ) Tj ET Q q 0 0 0 rg BT 266.47 684.25 Td (part ) Tj ET Q q 0 0 0 rg BT 284.52 684.25 Td (of ) Tj ET Q q 0 0 0 rg BT 295.35 684.25 Td (Commission ) Tj ET Q q 0 0 0 rg BT 348.41 684.25 Td (File ) Tj ET Q q 0 0 0 rg BT 366.47 684.25 Td (Number ) Tj ET Q q 0 0 0 rg BT 401.74 684.25 Td (1-1) Tj ET Q q 0 0 0 rg BT 414.70 684.25 Td (136.) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 35.5 655.75 m 81.5 655.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 85.5 655.75 m 535.5 655.75 l s 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 539.5 655.75 m 575.5 655.75 l s BT /F2 8.00 Tf ET q 0 0 0 rg BT 38.00 659.98 Td (Exhibit No.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 660.00 Td (  ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 88.00 659.98 Td (Description) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 660.00 Td (    ) Tj ET Q BT /F2 8.00 Tf ET q 0 0 0 rg BT 542.85 659.98 Td (Page No) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.05 644.9833984375 m 77.9884765625 644.9833984375 l s q 0 0 1 rg BT 66.05 646.32 Td (3a.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 635.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 644.9833984375 m 534.50390625 644.9833984375 l s q 0 0 1 rg BT 88.00 646.32 Td (Amended ) Tj ET Q q 0 0 1 rg BT 129.44 646.32 Td (and ) Tj ET Q q 0 0 1 rg BT 146.45 646.32 Td (Restated ) Tj ET Q q 0 0 1 rg BT 183.45 646.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 228.21 646.32 Td (of ) Tj ET Q q 0 0 1 rg BT 239.11 646.32 Td (Incorporation ) Tj ET Q q 0 0 1 rg BT 296.10 646.32 Td (of ) Tj ET Q q 0 0 1 rg BT 306.99 646.32 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 365.67 646.32 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 396.57 646.32 Td (Company ) Tj ET Q q 0 0 1 rg BT 438.02 646.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 494.45 646.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 522.00 646.32 Td (by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 634.9833984375 m 437.6142578125 634.9833984375 l s q 0 0 1 rg BT 88.00 636.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 127.68 636.32 Td (to ) Tj ET Q q 0 0 1 rg BT 137.96 636.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 169.90 636.32 Td (3a ) Tj ET Q q 0 0 1 rg BT 181.84 636.32 Td (to ) Tj ET Q q 0 0 1 rg BT 192.12 636.32 Td (the ) Tj ET Q q 0 0 1 rg BT 206.84 636.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 231.01 636.32 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 254.06 636.32 Td (for ) Tj ET Q q 0 0 1 rg BT 268.22 636.32 Td (the ) Tj ET Q q 0 0 1 rg BT 282.94 636.32 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 321.53 636.32 Td (period ) Tj ET Q q 0 0 1 rg BT 349.58 636.32 Td (ended ) Tj ET Q q 0 0 1 rg BT 375.95 636.32 Td (June ) Tj ET Q q 0 0 1 rg BT 396.78 636.32 Td (30, ) Tj ET Q q 0 0 1 rg BT 411.78 636.32 Td (2005\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 635.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 646.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 615.9833984375 m 78 615.9833984375 l s q 0 0 1 rg BT 65.50 617.32 Td (3b.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 596.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 615.9833984375 m 534.51025390625 615.9833984375 l s q 0 0 1 rg BT 88.00 617.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 132.26 617.32 Td (of ) Tj ET Q q 0 0 1 rg BT 142.65 617.32 Td (Correction ) Tj ET Q q 0 0 1 rg BT 187.48 617.32 Td (to ) Tj ET Q q 0 0 1 rg BT 197.32 617.32 Td (the ) Tj ET Q q 0 0 1 rg BT 211.15 617.32 Td (Amended ) Tj ET Q q 0 0 1 rg BT 252.09 617.32 Td (and ) Tj ET Q q 0 0 1 rg BT 268.59 617.32 Td (Restated ) Tj ET Q q 0 0 1 rg BT 305.08 617.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 349.34 617.32 Td (of ) Tj ET Q q 0 0 1 rg BT 359.74 617.32 Td (Incorporation, ) Tj ET Q q 0 0 1 rg BT 418.72 617.32 Td (ef) Tj ET Q q 0 0 1 rg BT 426.31 617.32 Td (fective ) Tj ET Q q 0 0 1 rg BT 455.58 617.32 Td (as ) Tj ET Q q 0 0 1 rg BT 465.97 617.32 Td (of ) Tj ET Q q 0 0 1 rg BT 476.36 617.32 Td (December ) Tj ET Q q 0 0 1 rg BT 519.51 617.32 Td (24, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 605.9833984375 m 534.5087890625 605.9833984375 l s q 0 0 1 rg BT 88.00 607.32 Td (2009 ) Tj ET Q q 0 0 1 rg BT 110.69 607.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 167.23 607.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 194.90 607.32 Td (by ) Tj ET Q q 0 0 1 rg BT 207.59 607.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 247.46 607.32 Td (to ) Tj ET Q q 0 0 1 rg BT 257.92 607.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 290.05 607.32 Td (3b ) Tj ET Q q 0 0 1 rg BT 302.74 607.32 Td (to ) Tj ET Q q 0 0 1 rg BT 313.20 607.32 Td (the ) Tj ET Q q 0 0 1 rg BT 328.10 607.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 352.46 607.32 Td (10-K ) Tj ET Q q 0 0 1 rg BT 375.70 607.32 Td (for ) Tj ET Q q 0 0 1 rg BT 390.04 607.32 Td (the ) Tj ET Q q 0 0 1 rg BT 404.94 607.32 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 429.28 607.32 Td (year ) Tj ET Q q 0 0 1 rg BT 449.18 607.32 Td (ended ) Tj ET Q q 0 0 1 rg BT 475.74 607.32 Td (December ) Tj ET Q q 0 0 1 rg BT 519.51 607.32 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 595.9833984375 m 113.830078125 595.9833984375 l s q 0 0 1 rg BT 88.00 597.32 Td (2010\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 596.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 617.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.05 576.9833984375 m 77.9884765625 576.9833984375 l s q 0 0 1 rg BT 66.05 578.32 Td (3c.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 567.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 576.9833984375 m 534.501953125 576.9833984375 l s q 0 0 1 rg BT 88.00 578.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 132.23 578.32 Td (of ) Tj ET Q q 0 0 1 rg BT 142.14 578.32 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 193.60 578.32 Td (to ) Tj ET Q q 0 0 1 rg BT 203.41 578.32 Td (the ) Tj ET Q q 0 0 1 rg BT 217.20 578.32 Td (Amended ) Tj ET Q q 0 0 1 rg BT 258.11 578.32 Td (and ) Tj ET Q q 0 0 1 rg BT 274.58 578.32 Td (Restated ) Tj ET Q q 0 0 1 rg BT 311.04 578.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 355.27 578.32 Td (of ) Tj ET Q q 0 0 1 rg BT 365.63 578.32 Td (Incorporation, ) Tj ET Q q 0 0 1 rg BT 424.58 578.32 Td (ef) Tj ET Q q 0 0 1 rg BT 432.17 578.32 Td (fective ) Tj ET Q q 0 0 1 rg BT 461.40 578.32 Td (as ) Tj ET Q q 0 0 1 rg BT 471.76 578.32 Td (of ) Tj ET Q q 0 0 1 rg BT 482.11 578.32 Td (May ) Tj ET Q q 0 0 1 rg BT 502.47 578.32 Td (7, ) Tj ET Q q 0 0 1 rg BT 512.00 578.32 Td (2010 ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 566.9833984375 m 532.013671875 566.9833984375 l s q 0 0 1 rg BT 88.00 568.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 144.22 568.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 171.57 568.32 Td (by ) Tj ET Q q 0 0 1 rg BT 183.93 568.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 223.47 568.32 Td (to ) Tj ET Q q 0 0 1 rg BT 233.61 568.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 265.41 568.32 Td (3a ) Tj ET Q q 0 0 1 rg BT 277.21 568.32 Td (to ) Tj ET Q q 0 0 1 rg BT 287.35 568.32 Td (the ) Tj ET Q q 0 0 1 rg BT 301.92 568.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 325.95 568.32 Td (8-K ) Tj ET Q q 0 0 1 rg BT 343.87 568.32 Td (dated ) Tj ET Q q 0 0 1 rg BT 367.88 568.32 Td (May ) Tj ET Q q 0 0 1 rg BT 388.57 568.32 Td (4, ) Tj ET Q q 0 0 1 rg BT 398.43 568.32 Td (2010 ) Tj ET Q q 0 0 1 rg BT 420.79 568.32 Td (and ) Tj ET Q q 0 0 1 rg BT 437.59 568.32 Td (filed ) Tj ET Q q 0 0 1 rg BT 458.27 568.32 Td (on ) Tj ET Q q 0 0 1 rg BT 470.63 568.32 Td (May ) Tj ET Q q 0 0 1 rg BT 491.32 568.32 Td (10, ) Tj ET Q q 0 0 1 rg BT 506.18 568.32 Td (2010\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 567.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 578.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 547.9833984375 m 78 547.9833984375 l s q 0 0 1 rg BT 65.50 549.32 Td (3d.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 538.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 547.9833984375 m 534.501953125 547.9833984375 l s q 0 0 1 rg BT 88.00 549.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 132.23 549.32 Td (of ) Tj ET Q q 0 0 1 rg BT 142.14 549.32 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 193.60 549.32 Td (to ) Tj ET Q q 0 0 1 rg BT 203.41 549.32 Td (the ) Tj ET Q q 0 0 1 rg BT 217.20 549.32 Td (Amended ) Tj ET Q q 0 0 1 rg BT 258.11 549.32 Td (and ) Tj ET Q q 0 0 1 rg BT 274.58 549.32 Td (Restated ) Tj ET Q q 0 0 1 rg BT 311.04 549.32 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 355.27 549.32 Td (of ) Tj ET Q q 0 0 1 rg BT 365.63 549.32 Td (Incorporation, ) Tj ET Q q 0 0 1 rg BT 424.58 549.32 Td (ef) Tj ET Q q 0 0 1 rg BT 432.17 549.32 Td (fective ) Tj ET Q q 0 0 1 rg BT 461.40 549.32 Td (as ) Tj ET Q q 0 0 1 rg BT 471.76 549.32 Td (of ) Tj ET Q q 0 0 1 rg BT 482.11 549.32 Td (May ) Tj ET Q q 0 0 1 rg BT 502.47 549.32 Td (7, ) Tj ET Q q 0 0 1 rg BT 512.00 549.32 Td (2010 ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 537.9833984375 m 532.0087890625 537.9833984375 l s q 0 0 1 rg BT 88.00 539.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 144.19 539.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 171.51 539.32 Td (by ) Tj ET Q q 0 0 1 rg BT 183.84 539.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 223.36 539.32 Td (to ) Tj ET Q q 0 0 1 rg BT 233.47 539.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 265.24 539.32 Td (3b ) Tj ET Q q 0 0 1 rg BT 277.57 539.32 Td (to ) Tj ET Q q 0 0 1 rg BT 287.68 539.32 Td (the ) Tj ET Q q 0 0 1 rg BT 302.23 539.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 326.23 539.32 Td (8-K ) Tj ET Q q 0 0 1 rg BT 344.12 539.32 Td (dated ) Tj ET Q q 0 0 1 rg BT 368.10 539.32 Td (May ) Tj ET Q q 0 0 1 rg BT 388.76 539.32 Td (4, ) Tj ET Q q 0 0 1 rg BT 398.60 539.32 Td (2010 ) Tj ET Q q 0 0 1 rg BT 420.93 539.32 Td (and ) Tj ET Q q 0 0 1 rg BT 437.70 539.32 Td (filed ) Tj ET Q q 0 0 1 rg BT 458.35 539.32 Td (on ) Tj ET Q q 0 0 1 rg BT 470.69 539.32 Td (May ) Tj ET Q q 0 0 1 rg BT 491.35 539.32 Td (10, ) Tj ET Q q 0 0 1 rg BT 506.18 539.32 Td (2010\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 538.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 549.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.05 518.9833984375 m 77.9884765625 518.9833984375 l s q 0 0 1 rg BT 66.05 520.32 Td (3e.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 509.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 518.9833984375 m 534.51611328125 518.9833984375 l s q 0 0 1 rg BT 88.00 520.32 Td (Bylaws ) Tj ET Q q 0 0 1 rg BT 119.58 520.32 Td (of ) Tj ET Q q 0 0 1 rg BT 129.49 520.32 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 187.17 520.32 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 217.09 520.32 Td (Company) Tj ET Q q 0 0 1 rg BT 255.33 520.32 Td (, ) Tj ET Q q 0 0 1 rg BT 259.41 520.32 Td (as ) Tj ET Q q 0 0 1 rg BT 269.32 520.32 Td (amended ) Tj ET Q q 0 0 1 rg BT 306.99 520.32 Td (as ) Tj ET Q q 0 0 1 rg BT 316.90 520.32 Td (of ) Tj ET Q q 0 0 1 rg BT 326.81 520.32 Td (November ) Tj ET Q q 0 0 1 rg BT 370.59 520.32 Td (2, ) Tj ET Q q 0 0 1 rg BT 379.67 520.32 Td (2016 ) Tj ET Q q 0 0 1 rg BT 401.25 520.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 456.69 520.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 483.25 520.32 Td (by ) Tj ET Q q 0 0 1 rg BT 494.83 520.32 Td (reference ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 508.9833984375 m 432.1015625 508.9833984375 l s q 0 0 1 rg BT 88.00 510.32 Td (to ) Tj ET Q q 0 0 1 rg BT 98.28 510.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 130.22 510.32 Td (3.1 ) Tj ET Q q 0 0 1 rg BT 145.22 510.32 Td (to ) Tj ET Q q 0 0 1 rg BT 155.50 510.32 Td (the ) Tj ET Q q 0 0 1 rg BT 170.22 510.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 194.39 510.32 Td (8-K ) Tj ET Q q 0 0 1 rg BT 212.44 510.32 Td (dated ) Tj ET Q q 0 0 1 rg BT 236.59 510.32 Td (November ) Tj ET Q q 0 0 1 rg BT 281.30 510.32 Td (2, ) Tj ET Q q 0 0 1 rg BT 291.30 510.32 Td (2016 ) Tj ET Q q 0 0 1 rg BT 313.80 510.32 Td (and ) Tj ET Q q 0 0 1 rg BT 330.74 510.32 Td (filed ) Tj ET Q q 0 0 1 rg BT 351.56 510.32 Td (November ) Tj ET Q q 0 0 1 rg BT 396.27 510.32 Td (4, ) Tj ET Q q 0 0 1 rg BT 406.27 510.32 Td (2016\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 509.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 520.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.05 491.32 Td (4a.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 480.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 491.32 Td (Letter ) Tj ET Q q 0 0 0 rg BT 114.40 491.32 Td (of ) Tj ET Q q 0 0 0 rg BT 124.98 491.32 Td (Agreement ) Tj ET Q q 0 0 0 rg BT 171.66 491.32 Td (dated ) Tj ET Q q 0 0 0 rg BT 195.85 491.32 Td (March ) Tj ET Q q 0 0 0 rg BT 224.48 491.32 Td (28, ) Tj ET Q q 0 0 0 rg BT 239.51 491.32 Td (1984 ) Tj ET Q q 0 0 0 rg BT 262.04 491.32 Td (\(incorporated ) Tj ET Q q 0 0 0 rg BT 318.43 491.32 Td (herein ) Tj ET Q q 0 0 0 rg BT 345.95 491.32 Td (by ) Tj ET Q q 0 0 0 rg BT 358.48 491.32 Td (reference ) Tj ET Q q 0 0 0 rg BT 398.19 491.32 Td (to ) Tj ET Q q 0 0 0 rg BT 408.50 491.32 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 440.47 491.32 Td (4 ) Tj ET Q q 0 0 0 rg BT 448.00 491.32 Td (to ) Tj ET Q q 0 0 0 rg BT 458.31 491.32 Td (the ) Tj ET Q q 0 0 0 rg BT 473.06 491.32 Td (Form ) Tj ET Q q 0 0 0 rg BT 497.26 491.32 Td (10-K ) Tj ET Q q 0 0 0 rg BT 520.34 491.32 Td (for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 481.32 Td (the ) Tj ET Q q 0 0 0 rg BT 102.72 481.32 Td (fiscal ) Tj ET Q q 0 0 0 rg BT 126.87 481.32 Td (year ) Tj ET Q q 0 0 0 rg BT 146.58 481.32 Td (ended ) Tj ET Q q 0 0 0 rg BT 172.96 481.32 Td (December ) Tj ET Q q 0 0 0 rg BT 216.54 481.32 Td (31, ) Tj ET Q q 0 0 0 rg BT 231.54 481.32 Td (1983\).) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 480.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 491.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 65.50 462.32 Td (4b.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 441.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 462.32 Td (Indenture, ) Tj ET Q q 0 0 0 rg BT 131.97 462.32 Td (dated ) Tj ET Q q 0 0 0 rg BT 156.78 462.32 Td (as ) Tj ET Q q 0 0 0 rg BT 168.26 462.32 Td (of ) Tj ET Q q 0 0 0 rg BT 179.75 462.32 Td (June ) Tj ET Q q 0 0 0 rg BT 201.23 462.32 Td (1, ) Tj ET Q q 0 0 0 rg BT 211.89 462.32 Td (1993, ) Tj ET Q q 0 0 0 rg BT 237.54 462.32 Td (between ) Tj ET Q q 0 0 0 rg BT 274.01 462.32 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 333.27 462.32 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 364.77 462.32 Td (Company ) Tj ET Q q 0 0 0 rg BT 406.81 462.32 Td (and ) Tj ET Q q 0 0 0 rg BT 424.40 462.32 Td (JPMor) Tj ET Q q 0 0 0 rg BT 450.99 462.32 Td (gan ) Tj ET Q q 0 0 0 rg BT 468.49 462.32 Td (Chase ) Tj ET Q q 0 0 0 rg BT 496.08 462.32 Td (Bank ) Tj ET Q q 0 0 0 rg BT 520.34 462.32 Td (\(as ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 452.32 Td (successor ) Tj ET Q q 0 0 0 rg BT 129.62 452.32 Td (trustee ) Tj ET Q q 0 0 0 rg BT 159.58 452.32 Td (to ) Tj ET Q q 0 0 0 rg BT 170.51 452.32 Td (The ) Tj ET Q q 0 0 0 rg BT 189.27 452.32 Td (Chase ) Tj ET Q q 0 0 0 rg BT 217.00 452.32 Td (Manhattan ) Tj ET Q q 0 0 0 rg BT 263.07 452.32 Td (Bank ) Tj ET Q q 0 0 0 rg BT 287.48 452.32 Td (\(National ) Tj ET Q q 0 0 0 rg BT 328.09 452.32 Td (Association\)\) ) Tj ET Q q 0 0 0 rg BT 384.99 452.32 Td (\(incorporated ) Tj ET Q q 0 0 0 rg BT 442.15 452.32 Td (herein ) Tj ET Q q 0 0 0 rg BT 470.44 452.32 Td (by ) Tj ET Q q 0 0 0 rg BT 483.74 452.32 Td (reference ) Tj ET Q q 0 0 0 rg BT 524.23 452.32 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 442.32 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 119.94 442.32 Td (4.1 ) Tj ET Q q 0 0 0 rg BT 134.94 442.32 Td (to ) Tj ET Q q 0 0 0 rg BT 145.22 442.32 Td (the ) Tj ET Q q 0 0 0 rg BT 159.94 442.32 Td (Form ) Tj ET Q q 0 0 0 rg BT 184.11 442.32 Td (8-K ) Tj ET Q q 0 0 0 rg BT 202.16 442.32 Td (dated ) Tj ET Q q 0 0 0 rg BT 226.32 442.32 Td (May ) Tj ET Q q 0 0 0 rg BT 247.15 442.32 Td (27, ) Tj ET Q q 0 0 0 rg BT 262.15 442.32 Td (1993 ) Tj ET Q q 0 0 0 rg BT 284.65 442.32 Td (and ) Tj ET Q q 0 0 0 rg BT 301.58 442.32 Td (filed ) Tj ET Q q 0 0 0 rg BT 322.41 442.32 Td (on ) Tj ET Q q 0 0 0 rg BT 334.91 442.32 Td (June ) Tj ET Q q 0 0 0 rg BT 355.74 442.32 Td (3, ) Tj ET Q q 0 0 0 rg BT 365.74 442.32 Td (1993\).) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 441.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 462.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 66.05 423.32 Td (4c.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 412.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 423.32 Td (Form ) Tj ET Q q 0 0 0 rg BT 113.00 423.32 Td (of ) Tj ET Q q 0 0 0 rg BT 124.66 423.32 Td (7.15% ) Tj ET Q q 0 0 0 rg BT 153.82 423.32 Td (Debenture ) Tj ET Q q 0 0 0 rg BT 198.80 423.32 Td (due ) Tj ET Q q 0 0 0 rg BT 216.56 423.32 Td (2023 ) Tj ET Q q 0 0 0 rg BT 239.89 423.32 Td (of ) Tj ET Q q 0 0 0 rg BT 251.55 423.32 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 310.99 423.32 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 342.66 423.32 Td (Company ) Tj ET Q q 0 0 0 rg BT 384.88 423.32 Td (\(incorporated ) Tj ET Q q 0 0 0 rg BT 442.07 423.32 Td (herein ) Tj ET Q q 0 0 0 rg BT 470.39 423.32 Td (by ) Tj ET Q q 0 0 0 rg BT 483.72 423.32 Td (reference ) Tj ET Q q 0 0 0 rg BT 524.23 423.32 Td (to ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 413.32 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 119.94 413.32 Td (4.2 ) Tj ET Q q 0 0 0 rg BT 134.94 413.32 Td (to ) Tj ET Q q 0 0 0 rg BT 145.22 413.32 Td (the ) Tj ET Q q 0 0 0 rg BT 159.94 413.32 Td (Form ) Tj ET Q q 0 0 0 rg BT 184.11 413.32 Td (8-K ) Tj ET Q q 0 0 0 rg BT 202.16 413.32 Td (dated ) Tj ET Q q 0 0 0 rg BT 226.32 413.32 Td (May ) Tj ET Q q 0 0 0 rg BT 247.15 413.32 Td (27, ) Tj ET Q q 0 0 0 rg BT 262.15 413.32 Td (1993 ) Tj ET Q q 0 0 0 rg BT 284.65 413.32 Td (and ) Tj ET Q q 0 0 0 rg BT 301.58 413.32 Td (filed ) Tj ET Q q 0 0 0 rg BT 322.41 413.32 Td (on ) Tj ET Q q 0 0 0 rg BT 334.91 413.32 Td (June ) Tj ET Q q 0 0 0 rg BT 355.74 413.32 Td (3, ) Tj ET Q q 0 0 0 rg BT 365.74 413.32 Td (1993\).) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 412.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 423.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 392.9833984375 m 78 392.9833984375 l s q 0 0 1 rg BT 65.50 394.32 Td (4d.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 383.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 392.9833984375 m 534.5087890625 392.9833984375 l s q 0 0 1 rg BT 88.00 394.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 113.00 394.32 Td (of ) Tj ET Q q 0 0 1 rg BT 124.66 394.32 Td (6.80% ) Tj ET Q q 0 0 1 rg BT 153.82 394.32 Td (Debenture ) Tj ET Q q 0 0 1 rg BT 198.80 394.32 Td (due ) Tj ET Q q 0 0 1 rg BT 216.56 394.32 Td (2026 ) Tj ET Q q 0 0 1 rg BT 239.89 394.32 Td (of ) Tj ET Q q 0 0 1 rg BT 251.55 394.32 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 310.99 394.32 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 342.66 394.32 Td (Company ) Tj ET Q q 0 0 1 rg BT 384.88 394.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 442.07 394.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 470.39 394.32 Td (by ) Tj ET Q q 0 0 1 rg BT 483.72 394.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 524.23 394.32 Td (to ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 382.9833984375 m 387.62890625 382.9833984375 l s q 0 0 1 rg BT 88.00 384.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 119.94 384.32 Td (4e ) Tj ET Q q 0 0 1 rg BT 131.88 384.32 Td (to ) Tj ET Q q 0 0 1 rg BT 142.16 384.32 Td (the ) Tj ET Q q 0 0 1 rg BT 156.88 384.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 181.05 384.32 Td (10-K ) Tj ET Q q 0 0 1 rg BT 204.10 384.32 Td (for ) Tj ET Q q 0 0 1 rg BT 218.26 384.32 Td (the ) Tj ET Q q 0 0 1 rg BT 232.98 384.32 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 257.13 384.32 Td (year ) Tj ET Q q 0 0 1 rg BT 276.84 384.32 Td (ended ) Tj ET Q q 0 0 1 rg BT 303.21 384.32 Td (December ) Tj ET Q q 0 0 1 rg BT 346.80 384.32 Td (31, ) Tj ET Q q 0 0 1 rg BT 361.80 384.32 Td (1996\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 383.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 394.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.05 363.9833984375 m 77.9884765625 363.9833984375 l s q 0 0 1 rg BT 66.05 365.32 Td (4e.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 354.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 363.9833984375 m 534.5048828125 363.9833984375 l s q 0 0 1 rg BT 88.00 365.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.64 365.32 Td (of ) Tj ET Q q 0 0 1 rg BT 123.95 365.32 Td (6.875% ) Tj ET Q q 0 0 1 rg BT 157.75 365.32 Td (Debenture ) Tj ET Q q 0 0 1 rg BT 202.37 365.32 Td (due ) Tj ET Q q 0 0 1 rg BT 219.78 365.32 Td (2097 ) Tj ET Q q 0 0 1 rg BT 242.75 365.32 Td (of ) Tj ET Q q 0 0 1 rg BT 254.05 365.32 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 313.13 365.32 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 344.45 365.32 Td (Company ) Tj ET Q q 0 0 1 rg BT 386.31 365.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 443.14 365.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 471.10 365.32 Td (by ) Tj ET Q q 0 0 1 rg BT 484.07 365.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 524.23 365.32 Td (to ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 353.9833984375 m 410.978515625 353.9833984375 l s q 0 0 1 rg BT 88.00 355.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 119.94 355.32 Td (4f ) Tj ET Q q 0 0 1 rg BT 130.77 355.32 Td (to ) Tj ET Q q 0 0 1 rg BT 141.05 355.32 Td (the ) Tj ET Q q 0 0 1 rg BT 155.77 355.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 179.94 355.32 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 202.99 355.32 Td (for ) Tj ET Q q 0 0 1 rg BT 217.15 355.32 Td (the ) Tj ET Q q 0 0 1 rg BT 231.87 355.32 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 270.46 355.32 Td (period ) Tj ET Q q 0 0 1 rg BT 298.51 355.32 Td (ended ) Tj ET Q q 0 0 1 rg BT 324.88 355.32 Td (September ) Tj ET Q q 0 0 1 rg BT 370.15 355.32 Td (30, ) Tj ET Q q 0 0 1 rg BT 385.15 355.32 Td (1997\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 354.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 365.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.15 334.9833984375 m 77.980078125 334.9833984375 l s q 0 0 1 rg BT 67.15 336.32 Td (4f.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 315.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 334.9833984375 m 534.5 334.9833984375 l s q 0 0 1 rg BT 88.00 336.32 Td (Indenture, ) Tj ET Q q 0 0 1 rg BT 130.46 336.32 Td (dated ) Tj ET Q q 0 0 1 rg BT 153.77 336.32 Td (October ) Tj ET Q q 0 0 1 rg BT 187.63 336.32 Td (1, ) Tj ET Q q 0 0 1 rg BT 196.78 336.32 Td (2003, ) Tj ET Q q 0 0 1 rg BT 220.92 336.32 Td (between ) Tj ET Q q 0 0 1 rg BT 255.89 336.32 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 313.65 336.32 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 343.64 336.32 Td (Company) Tj ET Q q 0 0 1 rg BT 381.87 336.32 Td (, ) Tj ET Q q 0 0 1 rg BT 386.02 336.32 Td (as ) Tj ET Q q 0 0 1 rg BT 396.00 336.32 Td (Issuer) Tj ET Q q 0 0 1 rg BT 419.48 336.32 Td (, ) Tj ET Q q 0 0 1 rg BT 423.63 336.32 Td (and ) Tj ET Q q 0 0 1 rg BT 439.72 336.32 Td (JPMor) Tj ET Q q 0 0 1 rg BT 466.22 336.32 Td (gan ) Tj ET Q q 0 0 1 rg BT 482.30 336.32 Td (Chase ) Tj ET Q q 0 0 1 rg BT 508.39 336.32 Td (Bank, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 324.9833984375 m 534.5166015625 324.9833984375 l s q 0 0 1 rg BT 88.00 326.32 Td (as ) Tj ET Q q 0 0 1 rg BT 99.68 326.32 Td (T) Tj ET Q q 0 0 1 rg BT 105.44 326.32 Td (rustee ) Tj ET Q q 0 0 1 rg BT 132.93 326.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 190.41 326.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 219.01 326.32 Td (by ) Tj ET Q q 0 0 1 rg BT 232.62 326.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 273.42 326.32 Td (to ) Tj ET Q q 0 0 1 rg BT 284.81 326.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 317.87 326.32 Td (4q ) Tj ET Q q 0 0 1 rg BT 331.49 326.32 Td (to ) Tj ET Q q 0 0 1 rg BT 342.88 326.32 Td (the ) Tj ET Q q 0 0 1 rg BT 358.71 326.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 384.00 326.32 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 408.16 326.32 Td (for ) Tj ET Q q 0 0 1 rg BT 423.44 326.32 Td (the ) Tj ET Q q 0 0 1 rg BT 439.27 326.32 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 478.98 326.32 Td (period ) Tj ET Q q 0 0 1 rg BT 508.14 326.32 Td (ended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 314.9833984375 m 174.09375 314.9833984375 l s q 0 0 1 rg BT 88.00 316.32 Td (September ) Tj ET Q q 0 0 1 rg BT 133.26 316.32 Td (30, ) Tj ET Q q 0 0 1 rg BT 148.26 316.32 Td (2003\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 315.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 336.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 295.9833984375 m 78 295.9833984375 l s q 0 0 1 rg BT 65.50 297.32 Td (4g.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 286.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 295.9833984375 m 534.50390625 295.9833984375 l s q 0 0 1 rg BT 88.00 297.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.39 297.32 Td (of ) Tj ET Q q 0 0 1 rg BT 123.44 297.32 Td (Floating ) Tj ET Q q 0 0 1 rg BT 159.49 297.32 Td (Rate ) Tj ET Q q 0 0 1 rg BT 180.54 297.32 Td (Convertible ) Tj ET Q q 0 0 1 rg BT 230.47 297.32 Td (Senior ) Tj ET Q q 0 0 1 rg BT 259.30 297.32 Td (Debenture ) Tj ET Q q 0 0 1 rg BT 303.66 297.32 Td (due ) Tj ET Q q 0 0 1 rg BT 320.82 297.32 Td (2023 ) Tj ET Q q 0 0 1 rg BT 343.54 297.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 400.12 297.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 427.83 297.32 Td (by ) Tj ET Q q 0 0 1 rg BT 440.55 297.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 480.45 297.32 Td (to ) Tj ET Q q 0 0 1 rg BT 490.95 297.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 523.11 297.32 Td (4s ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 285.9833984375 m 368.205078125 285.9833984375 l s q 0 0 1 rg BT 88.00 287.32 Td (to ) Tj ET Q q 0 0 1 rg BT 98.28 287.32 Td (the ) Tj ET Q q 0 0 1 rg BT 113.00 287.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 137.17 287.32 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 160.22 287.32 Td (for ) Tj ET Q q 0 0 1 rg BT 174.38 287.32 Td (the ) Tj ET Q q 0 0 1 rg BT 189.09 287.32 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 227.69 287.32 Td (period ) Tj ET Q q 0 0 1 rg BT 255.73 287.32 Td (ended ) Tj ET Q q 0 0 1 rg BT 282.11 287.32 Td (September ) Tj ET Q q 0 0 1 rg BT 327.38 287.32 Td (30, ) Tj ET Q q 0 0 1 rg BT 342.38 287.32 Td (2003\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 286.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 297.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 266.9833984375 m 78 266.9833984375 l s q 0 0 1 rg BT 65.50 268.32 Td (4h.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 257.00 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 266.0833984375 m 534.50146484375 266.0833984375 l s q 0 0 1 rg BT 88.00 267.42 Td (Specimen ) Tj ET Q q 0 0 1 rg BT 129.49 267.42 Td (Certificate ) Tj ET Q q 0 0 1 rg BT 173.74 267.42 Td (of ) Tj ET Q q 0 0 1 rg BT 184.12 267.42 Td (Common ) Tj ET Q q 0 0 1 rg BT 223.40 267.42 Td (Stock ) Tj ET Q q 0 0 1 rg BT 248.23 267.42 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 304.15 267.42 Td (herein ) Tj ET Q q 0 0 1 rg BT 331.19 267.42 Td (by ) Tj ET Q q 0 0 1 rg BT 343.24 267.42 Td (reference ) Tj ET Q q 0 0 1 rg BT 382.48 267.42 Td (to ) Tj ET Q q 0 0 1 rg BT 392.31 267.42 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 423.80 267.42 Td (4s ) Tj ET Q q 0 0 1 rg BT 434.75 267.42 Td (to ) Tj ET Q q 0 0 1 rg BT 444.58 267.42 Td (the ) Tj ET Q q 0 0 1 rg BT 458.85 267.42 Td (Form ) Tj ET Q q 0 0 1 rg BT 482.57 267.42 Td (10-K for the ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 256.0833984375 m 242.6533203125 256.0833984375 l s q 0 0 1 rg BT 88.00 257.42 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 112.16 257.42 Td (year ) Tj ET Q q 0 0 1 rg BT 131.86 257.42 Td (ended ) Tj ET Q q 0 0 1 rg BT 158.24 257.42 Td (December ) Tj ET Q q 0 0 1 rg BT 201.82 257.42 Td (31, ) Tj ET Q q 0 0 1 rg BT 216.82 257.42 Td (2003\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 257.00 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 268.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.7 237.9833984375 m 77.9783203125 237.9833984375 l s q 0 0 1 rg BT 67.70 239.32 Td (4i.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 237.08339843750002 m 531.9306640625 237.08339843750002 l s q 0 0 1 rg BT 88.00 238.42 Td (Form of Fourth Supplemental Indenture between Bristol-Myers Squibb Company and ) Tj ET Q q 0 0 1 rg BT 433.88 238.42 Td (The Bank of New ) Tj ET Q q 0 0 1 rg BT 507.38 238.42 Td (Y) Tj ET Q q 0 0 1 rg BT 513.60 238.42 Td (ork, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 227.08339843750002 m 532.326171875 227.08339843750002 l s q 0 0 1 rg BT 88.00 228.42 Td (as ) Tj ET Q q 0 0 1 rg BT 98.65 228.42 Td (T) Tj ET Q q 0 0 1 rg BT 104.41 228.42 Td (rustee, to the indenture dated June 1, 1993 \(incorporated herein by reference to Exhibit 4r to the Form 8-K ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 217.08339843750002 m 330.1630859375 217.08339843750002 l s q 0 0 1 rg BT 88.00 218.42 Td (dated November 20, 2006 and filed on November 27, 2006\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 239.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.7 198.9833984375 m 77.9783203125 198.9833984375 l s q 0 0 1 rg BT 67.70 200.32 Td (4j.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 84.00 189.42 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 198.08339843750002 m 502.6142578125 198.08339843750002 l s q 0 0 1 rg BT 88.00 199.42 Td (Form of 5.875% Notes due 2036 \(incorporated herein by reference to Exhibit 4s to the Form 8-K dated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 188.08339843750002 m 293.5078125 188.08339843750002 l s q 0 0 1 rg BT 88.00 189.42 Td (November 20, 2006 and filed November 27, 2006\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 538.00 189.42 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 200.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 169.9833984375 m 78 169.9833984375 l s q 0 0 1 rg BT 65.50 171.32 Td (4k.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 169.9833984375 m 534.501953125 169.9833984375 l s q 0 0 1 rg BT 88.00 171.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 113.98 171.32 Td (of ) Tj ET Q q 0 0 1 rg BT 126.62 171.32 Td (4.625% ) Tj ET Q q 0 0 1 rg BT 161.76 171.32 Td (Notes ) Tj ET Q q 0 0 1 rg BT 189.40 171.32 Td (due ) Tj ET Q q 0 0 1 rg BT 208.15 171.32 Td (2021 ) Tj ET Q q 0 0 1 rg BT 232.46 171.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 290.63 171.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 319.93 171.32 Td (by ) Tj ET Q q 0 0 1 rg BT 334.24 171.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 375.73 171.32 Td (to ) Tj ET Q q 0 0 1 rg BT 387.82 171.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 421.58 171.32 Td (4u ) Tj ET Q q 0 0 1 rg BT 435.89 171.32 Td (to ) Tj ET Q q 0 0 1 rg BT 447.98 171.32 Td (the ) Tj ET Q q 0 0 1 rg BT 464.50 171.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 490.48 171.32 Td (8-K ) Tj ET Q q 0 0 1 rg BT 510.35 171.32 Td (dated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 159.9833984375 m 293.5078125 159.9833984375 l s q 0 0 1 rg BT 88.00 161.32 Td (November 20, ) Tj ET Q q 0 0 1 rg BT 147.71 161.32 Td (2006 ) Tj ET Q q 0 0 1 rg BT 170.21 161.32 Td (and ) Tj ET Q q 0 0 1 rg BT 187.15 161.32 Td (filed ) Tj ET Q q 0 0 1 rg BT 207.97 161.32 Td (November 27, ) Tj ET Q q 0 0 1 rg BT 267.68 161.32 Td (2006\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 171.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.7 140.9833984375 m 77.9783203125 140.9833984375 l s q 0 0 1 rg BT 67.70 142.32 Td (4l.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 140.08339843750002 m 524.708984375 140.08339843750002 l s q 0 0 1 rg BT 88.00 141.42 Td (Form of Fifth Supplemental Indenture between Bristol-Myers Squibb Company and ) Tj ET Q q 0 0 1 rg BT 426.66 141.42 Td (The Bank of New ) Tj ET Q q 0 0 1 rg BT 500.16 141.42 Td (Y) Tj ET Q q 0 0 1 rg BT 506.38 141.42 Td (ork, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 130.08339843750002 m 526.7744140625 130.08339843750002 l s q 0 0 1 rg BT 88.00 131.42 Td (as ) Tj ET Q q 0 0 1 rg BT 98.65 131.42 Td (T) Tj ET Q q 0 0 1 rg BT 104.41 131.42 Td (rustee, to the indenture dated June 1, 1993 \(incorporated herein by reference to Exhibit 4.1 to the Form 8-) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 120.08339843750002 m 282.130859375 120.08339843750002 l s q 0 0 1 rg BT 88.00 121.42 Td (K dated May 1, 2008 and filed on May 7, 2008\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 142.32 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 62.7 101.9833984375 m 77.9783203125 101.9833984375 l s q 0 0 1 rg BT 62.70 103.32 Td (4m.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 101.9833984375 m 534.50146484375 101.9833984375 l s q 0 0 1 rg BT 88.00 103.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.04 103.32 Td (of ) Tj ET Q q 0 0 1 rg BT 122.73 103.32 Td (6.125% ) Tj ET Q q 0 0 1 rg BT 155.93 103.32 Td (Notes ) Tj ET Q q 0 0 1 rg BT 181.62 103.32 Td (due ) Tj ET Q q 0 0 1 rg BT 198.43 103.32 Td (2038 ) Tj ET Q q 0 0 1 rg BT 220.79 103.32 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 277.02 103.32 Td (herein ) Tj ET Q q 0 0 1 rg BT 304.37 103.32 Td (by ) Tj ET Q q 0 0 1 rg BT 316.74 103.32 Td (reference ) Tj ET Q q 0 0 1 rg BT 356.29 103.32 Td (to ) Tj ET Q q 0 0 1 rg BT 366.43 103.32 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 398.24 103.32 Td (4.3 ) Tj ET Q q 0 0 1 rg BT 413.10 103.32 Td (to ) Tj ET Q q 0 0 1 rg BT 423.25 103.32 Td (the ) Tj ET Q q 0 0 1 rg BT 437.83 103.32 Td (Form ) Tj ET Q q 0 0 1 rg BT 461.87 103.32 Td (8-K ) Tj ET Q q 0 0 1 rg BT 479.78 103.32 Td (dated ) Tj ET Q q 0 0 1 rg BT 503.81 103.32 Td (May ) Tj ET Q q 0 0 1 rg BT 524.50 103.32 Td (1, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 91.9833984375 m 217.423828125 91.9833984375 l s q 0 0 1 rg BT 88.00 93.32 Td (2008 ) Tj ET Q q 0 0 1 rg BT 110.50 93.32 Td (and ) Tj ET Q q 0 0 1 rg BT 127.44 93.32 Td (filed ) Tj ET Q q 0 0 1 rg BT 148.26 93.32 Td (on ) Tj ET Q q 0 0 1 rg BT 160.76 93.32 Td (May ) Tj ET Q q 0 0 1 rg BT 181.59 93.32 Td (7, ) Tj ET Q q 0 0 1 rg BT 191.59 93.32 Td (2008\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 103.32 Td (‡) Tj ET Q endstream endobj 221 0 obj <> endobj 222 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.65 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 303.28 24.60 Td (10) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 740.7333984375 m 78 740.7333984375 l s q 0 0 1 rg BT 65.50 742.07 Td (4n.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 720.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 740.7333984375 m 534.5029296875 740.7333984375 l s q 0 0 1 rg BT 88.00 742.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 111.99 742.07 Td (of ) Tj ET Q q 0 0 1 rg BT 122.63 742.07 Td (Sixth ) Tj ET Q q 0 0 1 rg BT 146.07 742.07 Td (Supplemental ) Tj ET Q q 0 0 1 rg BT 203.38 742.07 Td (Indenture ) Tj ET Q q 0 0 1 rg BT 244.01 742.07 Td (between ) Tj ET Q q 0 0 1 rg BT 279.64 742.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 338.07 742.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 368.72 742.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 409.93 742.07 Td (and ) Tj ET Q q 0 0 1 rg BT 426.51 742.07 Td (The ) Tj ET Q q 0 0 1 rg BT 444.38 742.07 Td (Bank ) Tj ET Q q 0 0 1 rg BT 467.80 742.07 Td (of ) Tj ET Q q 0 0 1 rg BT 478.45 742.07 Td (New ) Tj ET Q q 0 0 1 rg BT 499.31 742.07 Td (Y) Tj ET Q q 0 0 1 rg BT 505.53 742.07 Td (ork, ) Tj ET Q q 0 0 1 rg BT 523.67 742.07 Td (as ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 730.7333984375 m 534.50390625 730.7333984375 l s q 0 0 1 rg BT 88.00 732.07 Td (T) Tj ET Q q 0 0 1 rg BT 93.76 732.07 Td (rustee, ) Tj ET Q q 0 0 1 rg BT 123.11 732.07 Td (to ) Tj ET Q q 0 0 1 rg BT 133.87 732.07 Td (the ) Tj ET Q q 0 0 1 rg BT 149.07 732.07 Td (indenture ) Tj ET Q q 0 0 1 rg BT 189.82 732.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 214.45 732.07 Td (June ) Tj ET Q q 0 0 1 rg BT 235.76 732.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 246.24 732.07 Td (1993 ) Tj ET Q q 0 0 1 rg BT 269.23 732.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 326.07 732.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 354.04 732.07 Td (by ) Tj ET Q q 0 0 1 rg BT 367.02 732.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 407.18 732.07 Td (to ) Tj ET Q q 0 0 1 rg BT 417.94 732.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 450.36 732.07 Td (4.1 ) Tj ET Q q 0 0 1 rg BT 465.84 732.07 Td (to ) Tj ET Q q 0 0 1 rg BT 476.60 732.07 Td (the ) Tj ET Q q 0 0 1 rg BT 491.80 732.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 516.45 732.07 Td (8-K ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 720.7333984375 m 279.0888671875 720.7333984375 l s q 0 0 1 rg BT 88.00 722.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 112.16 722.07 Td (July ) Tj ET Q q 0 0 1 rg BT 131.33 722.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 146.33 722.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 168.83 722.07 Td (and ) Tj ET Q q 0 0 1 rg BT 185.76 722.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 206.59 722.07 Td (on ) Tj ET Q q 0 0 1 rg BT 219.09 722.07 Td (July ) Tj ET Q q 0 0 1 rg BT 238.26 722.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 253.26 722.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 720.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 742.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 701.7333984375 m 78 701.7333984375 l s q 0 0 1 rg BT 65.50 703.07 Td (4o.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 701.7333984375 m 534.513671875 701.7333984375 l s q 0 0 1 rg BT 88.00 703.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.55 703.07 Td (of ) Tj ET Q q 0 0 1 rg BT 123.77 703.07 Td (2.000% ) Tj ET Q q 0 0 1 rg BT 157.48 703.07 Td (Notes ) Tj ET Q q 0 0 1 rg BT 183.69 703.07 Td (Due ) Tj ET Q q 0 0 1 rg BT 203.24 703.07 Td (2022 ) Tj ET Q q 0 0 1 rg BT 226.12 703.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 282.87 703.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 310.73 703.07 Td (by ) Tj ET Q q 0 0 1 rg BT 323.62 703.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 363.68 703.07 Td (to ) Tj ET Q q 0 0 1 rg BT 374.35 703.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 406.67 703.07 Td (4.3 ) Tj ET Q q 0 0 1 rg BT 422.06 703.07 Td (to ) Tj ET Q q 0 0 1 rg BT 432.72 703.07 Td (the ) Tj ET Q q 0 0 1 rg BT 447.82 703.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 472.37 703.07 Td (8-K ) Tj ET Q q 0 0 1 rg BT 490.81 703.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 515.34 703.07 Td (July ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 691.7333984375 m 235.763671875 691.7333984375 l s q 0 0 1 rg BT 88.00 693.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 103.00 693.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 125.50 693.07 Td (and ) Tj ET Q q 0 0 1 rg BT 142.44 693.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 163.26 693.07 Td (on ) Tj ET Q q 0 0 1 rg BT 175.76 693.07 Td (July ) Tj ET Q q 0 0 1 rg BT 194.93 693.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 209.93 693.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 703.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 672.7333984375 m 78 672.7333984375 l s q 0 0 1 rg BT 65.50 674.07 Td (4p.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 672.7333984375 m 534.513671875 672.7333984375 l s q 0 0 1 rg BT 88.00 674.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.55 674.07 Td (of ) Tj ET Q q 0 0 1 rg BT 123.77 674.07 Td (3.250% ) Tj ET Q q 0 0 1 rg BT 157.48 674.07 Td (Notes ) Tj ET Q q 0 0 1 rg BT 183.69 674.07 Td (Due ) Tj ET Q q 0 0 1 rg BT 203.24 674.07 Td (2042 ) Tj ET Q q 0 0 1 rg BT 226.12 674.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 282.87 674.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 310.73 674.07 Td (by ) Tj ET Q q 0 0 1 rg BT 323.62 674.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 363.68 674.07 Td (to ) Tj ET Q q 0 0 1 rg BT 374.35 674.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 406.67 674.07 Td (4.4 ) Tj ET Q q 0 0 1 rg BT 422.06 674.07 Td (to ) Tj ET Q q 0 0 1 rg BT 432.72 674.07 Td (the ) Tj ET Q q 0 0 1 rg BT 447.82 674.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 472.37 674.07 Td (8-K ) Tj ET Q q 0 0 1 rg BT 490.81 674.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 515.34 674.07 Td (July ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 662.7333984375 m 235.763671875 662.7333984375 l s q 0 0 1 rg BT 88.00 664.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 103.00 664.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 125.50 664.07 Td (and ) Tj ET Q q 0 0 1 rg BT 142.44 664.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 163.26 664.07 Td (on ) Tj ET Q q 0 0 1 rg BT 175.76 664.07 Td (July ) Tj ET Q q 0 0 1 rg BT 194.93 664.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 209.93 664.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 674.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 644.7333984375 m 78 644.7333984375 l s q 0 0 1 rg BT 65.50 646.07 Td (4q.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 644.7333984375 m 527.6337890625 644.7333984375 l s q 0 0 1 rg BT 88.00 646.07 Td (Seventh Supplemental Indenture, dated as of October 31, 2013, between Bristol-Myers Squibb Company and ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 634.7333984375 m 521.5205078125 634.7333984375 l s q 0 0 1 rg BT 88.00 636.07 Td (The Bank of New ) Tj ET Q q 0 0 1 rg BT 161.50 636.07 Td (Y) Tj ET Q q 0 0 1 rg BT 167.72 636.07 Td (ork Mellon, as ) Tj ET Q q 0 0 1 rg BT 228.08 636.07 Td (T) Tj ET Q q 0 0 1 rg BT 233.84 636.07 Td (rustee to the Indenture dated as of June 1, 1993 \(incorporated herein by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 624.7333984375 m 402.0771484375 624.7333984375 l s q 0 0 1 rg BT 88.00 626.07 Td (reference to Exhibit 4.1 to the Form 8-K dated and filed on October 31, 2013\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 646.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.7 607.7333984375 m 77.9783203125 607.7333984375 l s q 0 0 1 rg BT 67.70 609.07 Td (4r) Tj ET Q q 0 0 1 rg BT 75.48 609.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 607.7333984375 m 525.3828125 607.7333984375 l s q 0 0 1 rg BT 88.00 609.07 Td (Form of 1.750% Notes Due 2019 \(incorporated herein by reference to Exhibit 4.1 to the Form 8-K dated and ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 597.7333984375 m 196.8623046875 597.7333984375 l s q 0 0 1 rg BT 88.00 599.07 Td (filed on October 31, 2013\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 609.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.6 577.7333984375 m 77.9916015625 577.7333984375 l s q 0 0 1 rg BT 66.60 579.07 Td (4s.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 577.7333984375 m 525.3828125 577.7333984375 l s q 0 0 1 rg BT 88.00 579.07 Td (Form of 3.250% Notes Due 2023 \(incorporated herein by reference to Exhibit 4.1 to the Form 8-K dated and ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 567.7333984375 m 196.8623046875 567.7333984375 l s q 0 0 1 rg BT 88.00 569.07 Td (filed on October 31, 2013\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 579.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 67.7 548.7333984375 m 77.9783203125 548.7333984375 l s q 0 0 1 rg BT 67.70 550.07 Td (4t.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 548.7333984375 m 525.3828125 548.7333984375 l s q 0 0 1 rg BT 88.00 550.07 Td (Form of 4.500% Notes Due 2044 \(incorporated herein by reference to Exhibit 4.1 to the Form 8-K dated and ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 538.7333984375 m 196.8623046875 538.7333984375 l s q 0 0 1 rg BT 88.00 540.07 Td (filed on October 31, 2013\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 550.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 65.5 520.7333984375 m 78 520.7333984375 l s q 0 0 1 rg BT 65.50 522.07 Td (4u.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 520.7333984375 m 521.0712890625 520.7333984375 l s q 0 0 1 rg BT 88.00 522.07 Td (Eighth Supplemental Indenture, dated as of May 5, 2015, between Bristol-Myers Squibb Company and ) Tj ET Q q 0 0 1 rg BT 503.02 522.07 Td (The ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 510.7333984375 m 505.9736328125 510.7333984375 l s q 0 0 1 rg BT 88.00 512.07 Td (Bank of New ) Tj ET Q q 0 0 1 rg BT 143.45 512.07 Td (Y) Tj ET Q q 0 0 1 rg BT 149.67 512.07 Td (ork Mellon, as ) Tj ET Q q 0 0 1 rg BT 210.04 512.07 Td (T) Tj ET Q q 0 0 1 rg BT 215.79 512.07 Td (rustee, to the Indenture dated as of June 1, 1993 \(incorporated herein by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 500.7333984375 m 383.2001953125 500.7333984375 l s q 0 0 1 rg BT 88.00 502.07 Td (reference to Exhibit 4.1 to the Form 8-K dated and filed on May 5, 2015\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 522.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 66.1 481.7333984375 m 77.9505859375 481.7333984375 l s q 0 0 1 rg BT 66.10 483.07 Td (4v) Tj ET Q q 0 0 1 rg BT 75.45 483.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 481.7333984375 m 523.7373046875 481.7333984375 l s q 0 0 1 rg BT 88.00 483.07 Td (Form of €575,000,000 1.000% Notes Due 2025 \(incorporated herein by reference to Exhibit 4.2 to the Form ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 471.7333984375 m 237.130859375 471.7333984375 l s q 0 0 1 rg BT 88.00 473.07 Td (8-K dated and filed on May 5, 2015\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 483.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 63.9 452.7333984375 m 77.972265625 452.7333984375 l s q 0 0 1 rg BT 63.90 454.07 Td (4w) Tj ET Q q 0 0 1 rg BT 75.47 454.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 452.7333984375 m 523.7373046875 452.7333984375 l s q 0 0 1 rg BT 88.00 454.07 Td (Form of €575,000,000 1.750% Notes Due 2035 \(incorporated herein by reference to Exhibit 4.3 to the Form ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 442.7333984375 m 237.130859375 442.7333984375 l s q 0 0 1 rg BT 88.00 444.07 Td (8-K dated and filed on May 5, 2015\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 454.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 61.05 423.7333984375 m 77.9884765625 423.7333984375 l s q 0 0 1 rg BT 61.05 425.07 Td (10a.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 422.8333984375 m 497.0966796875 422.8333984375 l s q 0 0 1 rg BT 88.00 424.17 Td ($1,500,000,000 Five ) Tj ET Q q 0 0 1 rg BT 172.91 424.17 Td (Y) Tj ET Q q 0 0 1 rg BT 179.13 424.17 Td (ear Competitive ) Tj ET Q q 0 0 1 rg BT 245.22 424.17 Td (Advance and Revolving Credit Facility ) Tj ET Q q 0 0 1 rg BT 404.36 424.17 Td (Agreement dated as of ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 412.8333984375 m 529.416015625 412.8333984375 l s q 0 0 1 rg BT 88.00 414.17 Td (September 29, 201) Tj ET Q q 0 0 1 rg BT 162.89 414.17 Td (1 among Bristol-Myers Squibb Company) Tj ET Q q 0 0 1 rg BT 327.79 414.17 Td (, the borrowing subsidiaries, the lenders named in ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 402.8333984375 m 527.3359375 402.8333984375 l s q 0 0 1 rg BT 88.00 404.17 Td (the agreement, BNP) Tj ET Q q 0 0 1 rg BT 168.44 404.17 Td ( Paribas and ) Tj ET Q q 0 0 1 rg BT 219.64 404.17 Td (The Royal Bank of Scotland plc, as documentation agents, Bank of ) Tj ET Q q 0 0 1 rg BT 490.41 404.17 Td (America ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 392.8333984375 m 513.302734375 392.8333984375 l s q 0 0 1 rg BT 88.00 394.17 Td (N.A., as syndication agent, and JPMor) Tj ET Q q 0 0 1 rg BT 241.96 394.17 Td (gan Chase Bank, N.A. and Citibank, N.A., as administrative agents ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 382.8333984375 m 510.2802734375 382.8333984375 l s q 0 0 1 rg BT 88.00 384.17 Td (\(incorporated herein by reference to Exhibit 10.1 to the Form 8-K dated September 29, 201) Tj ET Q q 0 0 1 rg BT 452.52 384.17 Td (1 and filed on ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 372.8333984375 m 158.166015625 372.8333984375 l s q 0 0 1 rg BT 88.00 374.17 Td (October 4, 201) Tj ET Q q 0 0 1 rg BT 147.34 374.17 Td (1\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 425.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 354.7333984375 m 78 354.7333984375 l s q 0 0 1 rg BT 60.50 356.07 Td (10b.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 354.7333984375 m 519.611328125 354.7333984375 l s q 0 0 1 rg BT 88.00 356.07 Td (First ) Tj ET Q q 0 0 1 rg BT 108.29 356.07 Td (Amendment dated June 21, 2013 to the Five ) Tj ET Q q 0 0 1 rg BT 287.61 356.07 Td (Y) Tj ET Q q 0 0 1 rg BT 293.83 356.07 Td (ear Competitive ) Tj ET Q q 0 0 1 rg BT 359.92 356.07 Td (Advance and Revolving Credit Facility ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 344.7333984375 m 508.546875 344.7333984375 l s q 0 0 1 rg BT 88.00 346.07 Td (Agreement dated as of September 29, 201) Tj ET Q q 0 0 1 rg BT 255.63 346.07 Td (1 among Bristol-Myers Squibb Company) Tj ET Q q 0 0 1 rg BT 420.53 346.07 Td (, the several financial ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 334.7333984375 m 524.416015625 334.7333984375 l s q 0 0 1 rg BT 88.00 336.07 Td (institutions from time to time party to the agreement, and JPMor) Tj ET Q q 0 0 1 rg BT 345.83 336.07 Td (gan Chase Bank, N.A. and Citibank N.A. as ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 324.7333984375 m 510.6318359375 324.7333984375 l s q 0 0 1 rg BT 88.00 326.07 Td (administrative agents \(incorporated herein by reference to Exhibit 10a to the Form 10-Q for the quarterly ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 314.7333984375 m 204.083984375 314.7333984375 l s q 0 0 1 rg BT 88.00 316.07 Td (period ended June 30, 2013\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 356.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 61.05 294.7333984375 m 77.9884765625 294.7333984375 l s q 0 0 1 rg BT 61.05 296.07 Td (10c.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 293.8333984374999 m 531.2666015625 293.8333984374999 l s q 0 0 1 rg BT 88.00 295.17 Td ($1,500,000,000 Five ) Tj ET Q q 0 0 1 rg BT 172.91 295.17 Td (Y) Tj ET Q q 0 0 1 rg BT 179.13 295.17 Td (ear Competitive ) Tj ET Q q 0 0 1 rg BT 245.22 295.17 Td (Advance and Revolving Credit Facility ) Tj ET Q q 0 0 1 rg BT 404.36 295.17 Td (Agreement dated as of July 30, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 283.8333984374999 m 530.880859375 283.8333984374999 l s q 0 0 1 rg BT 88.00 285.17 Td (2012 among Bristol-Myers Squibb Company) Tj ET Q q 0 0 1 rg BT 267.90 285.17 Td (, the borrowing subsidiaries, the lenders named in the agreement, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 273.8333984374999 m 517.5556640625 273.8333984374999 l s q 0 0 1 rg BT 88.00 275.17 Td (Bank of ) Tj ET Q q 0 0 1 rg BT 121.89 275.17 Td (America N.A., Barclays Bank plc, Deutsche Bank Securities Inc., and ) Tj ET Q q 0 0 1 rg BT 403.84 275.17 Td (W) Tj ET Q q 0 0 1 rg BT 412.48 275.17 Td (ells Far) Tj ET Q q 0 0 1 rg BT 442.01 275.17 Td (go Bank, National ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 263.8333984374999 m 510.8076171875 263.8333984374999 l s q 0 0 1 rg BT 88.00 265.17 Td (Association as documentation agents, Citibank, N.A. and JPMor) Tj ET Q q 0 0 1 rg BT 345.84 265.17 Td (gan Chase Bank, N.A., as administrative ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 253.8333984374999 m 531.7744140625 253.8333984374999 l s q 0 0 1 rg BT 88.00 255.17 Td (agents \(incorporated herein by reference to Exhibit 10.1 to the Form 8-K dated July 26, 2012 and filed on July ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 243.8333984374999 m 128.830078125 243.8333984374999 l s q 0 0 1 rg BT 88.00 245.17 Td (31, 2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 296.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 225.7333984375 m 78 225.7333984375 l s q 0 0 1 rg BT 60.50 227.07 Td (10d.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 225.7333984375 m 534.5126953125 225.7333984375 l s q 0 0 1 rg BT 88.00 227.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 139.70 227.07 Td (and ) Tj ET Q q 0 0 1 rg BT 156.25 227.07 Td (W) Tj ET Q q 0 0 1 rg BT 164.89 227.07 Td (aiver ) Tj ET Q q 0 0 1 rg BT 187.14 227.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 211.07 227.07 Td (as ) Tj ET Q q 0 0 1 rg BT 221.67 227.07 Td (of ) Tj ET Q q 0 0 1 rg BT 232.27 227.07 Td (June ) Tj ET Q q 0 0 1 rg BT 252.87 227.07 Td (21, ) Tj ET Q q 0 0 1 rg BT 267.64 227.07 Td (2016, ) Tj ET Q q 0 0 1 rg BT 292.41 227.07 Td (to ) Tj ET Q q 0 0 1 rg BT 302.46 227.07 Td (the ) Tj ET Q q 0 0 1 rg BT 316.95 227.07 Td (Five ) Tj ET Q q 0 0 1 rg BT 336.66 227.07 Td (Y) Tj ET Q q 0 0 1 rg BT 342.88 227.07 Td (ear ) Tj ET Q q 0 0 1 rg BT 357.36 227.07 Td (Competitive ) Tj ET Q q 0 0 1 rg BT 408.57 227.07 Td (Advance ) Tj ET Q q 0 0 1 rg BT 446.37 227.07 Td (and ) Tj ET Q q 0 0 1 rg BT 463.08 227.07 Td (Revolving ) Tj ET Q q 0 0 1 rg BT 507.02 227.07 Td (Credit ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 215.7333984375 m 534.5068359375 215.7333984375 l s q 0 0 1 rg BT 88.00 217.07 Td (Facility ) Tj ET Q q 0 0 1 rg BT 120.13 217.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 166.58 217.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 190.26 217.07 Td (as ) Tj ET Q q 0 0 1 rg BT 200.62 217.07 Td (of ) Tj ET Q q 0 0 1 rg BT 210.97 217.07 Td (September ) Tj ET Q q 0 0 1 rg BT 255.76 217.07 Td (29, ) Tj ET Q q 0 0 1 rg BT 270.29 217.07 Td (201) Tj ET Q q 0 0 1 rg BT 284.91 217.07 Td (1 ) Tj ET Q q 0 0 1 rg BT 291.94 217.07 Td (among ) Tj ET Q q 0 0 1 rg BT 321.18 217.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 379.32 217.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 409.68 217.07 Td (Company) Tj ET Q q 0 0 1 rg BT 447.92 217.07 Td (, ) Tj ET Q q 0 0 1 rg BT 452.44 217.07 Td (the ) Tj ET Q q 0 0 1 rg BT 466.69 217.07 Td (several ) Tj ET Q q 0 0 1 rg BT 497.03 217.07 Td (financial ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 205.7333984375 m 534.50146484375 205.7333984375 l s q 0 0 1 rg BT 88.00 207.07 Td (institutions ) Tj ET Q q 0 0 1 rg BT 135.55 207.07 Td (from ) Tj ET Q q 0 0 1 rg BT 158.08 207.07 Td (time ) Tj ET Q q 0 0 1 rg BT 178.94 207.07 Td (to ) Tj ET Q q 0 0 1 rg BT 189.82 207.07 Td (time ) Tj ET Q q 0 0 1 rg BT 210.68 207.07 Td (party ) Tj ET Q q 0 0 1 rg BT 234.32 207.07 Td (to ) Tj ET Q q 0 0 1 rg BT 245.19 207.07 Td (the ) Tj ET Q q 0 0 1 rg BT 260.50 207.07 Td (agreement, ) Tj ET Q q 0 0 1 rg BT 307.74 207.07 Td (and ) Tj ET Q q 0 0 1 rg BT 325.27 207.07 Td (JPMor) Tj ET Q q 0 0 1 rg BT 351.76 207.07 Td (gan ) Tj ET Q q 0 0 1 rg BT 369.30 207.07 Td (Chase ) Tj ET Q q 0 0 1 rg BT 396.83 207.07 Td (Bank, ) Tj ET Q q 0 0 1 rg BT 423.53 207.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 446.07 207.07 Td (and ) Tj ET Q q 0 0 1 rg BT 463.60 207.07 Td (Citibank ) Tj ET Q q 0 0 1 rg BT 501.13 207.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 523.67 207.07 Td (as ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 195.7333984375 m 534.4990234375 195.7333984375 l s q 0 0 1 rg BT 88.00 197.07 Td (administrative ) Tj ET Q q 0 0 1 rg BT 147.45 197.07 Td (agents ) Tj ET Q q 0 0 1 rg BT 175.23 197.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 231.33 197.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 258.56 197.07 Td (by ) Tj ET Q q 0 0 1 rg BT 270.80 197.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 310.22 197.07 Td (to ) Tj ET Q q 0 0 1 rg BT 320.23 197.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 351.92 197.07 Td (10a ) Tj ET Q q 0 0 1 rg BT 368.59 197.07 Td (to ) Tj ET Q q 0 0 1 rg BT 378.61 197.07 Td (the ) Tj ET Q q 0 0 1 rg BT 393.07 197.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 416.97 197.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 439.77 197.07 Td (for ) Tj ET Q q 0 0 1 rg BT 453.66 197.07 Td (the ) Tj ET Q q 0 0 1 rg BT 468.12 197.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 506.45 197.07 Td (period ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 185.7333984375 m 176.037109375 185.7333984375 l s q 0 0 1 rg BT 88.00 187.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 114.38 187.07 Td (June ) Tj ET Q q 0 0 1 rg BT 135.21 187.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 150.21 187.07 Td (2016\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 227.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 61.05 166.7333984375 m 77.9884765625 166.7333984375 l s q 0 0 1 rg BT 61.05 168.07 Td (10e.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 166.7333984375 m 534.51220703125 166.7333984375 l s q 0 0 1 rg BT 88.00 168.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 140.64 168.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 165.50 168.07 Td (as ) Tj ET Q q 0 0 1 rg BT 177.04 168.07 Td (of ) Tj ET Q q 0 0 1 rg BT 188.57 168.07 Td (June ) Tj ET Q q 0 0 1 rg BT 210.11 168.07 Td (21, ) Tj ET Q q 0 0 1 rg BT 225.81 168.07 Td (2016, ) Tj ET Q q 0 0 1 rg BT 251.52 168.07 Td (to ) Tj ET Q q 0 0 1 rg BT 262.50 168.07 Td (the ) Tj ET Q q 0 0 1 rg BT 277.92 168.07 Td (Five ) Tj ET Q q 0 0 1 rg BT 298.43 168.07 Td (Y) Tj ET Q q 0 0 1 rg BT 304.65 168.07 Td (ear ) Tj ET Q q 0 0 1 rg BT 320.07 168.07 Td (Competitive ) Tj ET Q q 0 0 1 rg BT 372.00 168.07 Td (Advance ) Tj ET Q q 0 0 1 rg BT 410.75 168.07 Td (and ) Tj ET Q q 0 0 1 rg BT 428.39 168.07 Td (Revolving ) Tj ET Q q 0 0 1 rg BT 473.26 168.07 Td (Credit ) Tj ET Q q 0 0 1 rg BT 501.46 168.07 Td (Facility ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 156.7333984375 m 534.5146484375 156.7333984375 l s q 0 0 1 rg BT 88.00 158.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 135.26 158.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 159.76 158.07 Td (as ) Tj ET Q q 0 0 1 rg BT 170.92 158.07 Td (of ) Tj ET Q q 0 0 1 rg BT 182.09 158.07 Td (July ) Tj ET Q q 0 0 1 rg BT 201.60 158.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 216.94 158.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 239.78 158.07 Td (among ) Tj ET Q q 0 0 1 rg BT 269.83 158.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 328.78 158.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 359.96 158.07 Td (Company) Tj ET Q q 0 0 1 rg BT 398.20 158.07 Td (, ) Tj ET Q q 0 0 1 rg BT 403.53 158.07 Td (the ) Tj ET Q q 0 0 1 rg BT 418.59 158.07 Td (several ) Tj ET Q q 0 0 1 rg BT 449.74 158.07 Td (financial ) Tj ET Q q 0 0 1 rg BT 487.56 158.07 Td (institutions ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 146.7333984375 m 534.513671875 146.7333984375 l s q 0 0 1 rg BT 88.00 148.07 Td (from ) Tj ET Q q 0 0 1 rg BT 109.78 148.07 Td (time ) Tj ET Q q 0 0 1 rg BT 129.90 148.07 Td (to ) Tj ET Q q 0 0 1 rg BT 140.02 148.07 Td (time ) Tj ET Q q 0 0 1 rg BT 160.14 148.07 Td (party ) Tj ET Q q 0 0 1 rg BT 183.03 148.07 Td (to ) Tj ET Q q 0 0 1 rg BT 193.15 148.07 Td (the ) Tj ET Q q 0 0 1 rg BT 207.71 148.07 Td (agreement, ) Tj ET Q q 0 0 1 rg BT 254.20 148.07 Td (and ) Tj ET Q q 0 0 1 rg BT 270.98 148.07 Td (JPMor) Tj ET Q q 0 0 1 rg BT 297.47 148.07 Td (gan ) Tj ET Q q 0 0 1 rg BT 314.25 148.07 Td (Chase ) Tj ET Q q 0 0 1 rg BT 341.04 148.07 Td (Bank, ) Tj ET Q q 0 0 1 rg BT 366.99 148.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 388.78 148.07 Td (and ) Tj ET Q q 0 0 1 rg BT 405.56 148.07 Td (Citibank ) Tj ET Q q 0 0 1 rg BT 442.35 148.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 464.13 148.07 Td (as ) Tj ET Q q 0 0 1 rg BT 474.81 148.07 Td (administrative ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 136.7333984375 m 534.515625 136.7333984375 l s q 0 0 1 rg BT 88.00 138.07 Td (agents ) Tj ET Q q 0 0 1 rg BT 115.65 138.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 171.61 138.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 198.69 138.07 Td (by ) Tj ET Q q 0 0 1 rg BT 210.79 138.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 250.07 138.07 Td (to ) Tj ET Q q 0 0 1 rg BT 259.95 138.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 291.49 138.07 Td (10b ) Tj ET Q q 0 0 1 rg BT 308.59 138.07 Td (to ) Tj ET Q q 0 0 1 rg BT 318.46 138.07 Td (the ) Tj ET Q q 0 0 1 rg BT 332.78 138.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 356.55 138.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 379.20 138.07 Td (for ) Tj ET Q q 0 0 1 rg BT 392.96 138.07 Td (the ) Tj ET Q q 0 0 1 rg BT 407.27 138.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 445.47 138.07 Td (period ) Tj ET Q q 0 0 1 rg BT 473.11 138.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 499.09 138.07 Td (June ) Tj ET Q q 0 0 1 rg BT 519.52 138.07 Td (30, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 126.7333984375 m 113.830078125 126.7333984375 l s q 0 0 1 rg BT 88.00 128.07 Td (2016\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 168.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 62.15 107.7333984375 m 77.980078125 107.7333984375 l s q 0 0 1 rg BT 62.15 109.07 Td (10f.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 107.7333984375 m 534.5126953125 107.7333984375 l s q 0 0 1 rg BT 88.00 109.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 139.70 109.07 Td (and ) Tj ET Q q 0 0 1 rg BT 156.25 109.07 Td (W) Tj ET Q q 0 0 1 rg BT 164.89 109.07 Td (aiver ) Tj ET Q q 0 0 1 rg BT 187.14 109.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 211.07 109.07 Td (as ) Tj ET Q q 0 0 1 rg BT 221.67 109.07 Td (of ) Tj ET Q q 0 0 1 rg BT 232.27 109.07 Td (June ) Tj ET Q q 0 0 1 rg BT 252.87 109.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 267.64 109.07 Td (2017, ) Tj ET Q q 0 0 1 rg BT 292.41 109.07 Td (to ) Tj ET Q q 0 0 1 rg BT 302.46 109.07 Td (the ) Tj ET Q q 0 0 1 rg BT 316.95 109.07 Td (Five ) Tj ET Q q 0 0 1 rg BT 336.66 109.07 Td (Y) Tj ET Q q 0 0 1 rg BT 342.88 109.07 Td (ear ) Tj ET Q q 0 0 1 rg BT 357.36 109.07 Td (Competitive ) Tj ET Q q 0 0 1 rg BT 408.57 109.07 Td (Advance ) Tj ET Q q 0 0 1 rg BT 446.37 109.07 Td (and ) Tj ET Q q 0 0 1 rg BT 463.08 109.07 Td (Revolving ) Tj ET Q q 0 0 1 rg BT 507.02 109.07 Td (Credit ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 97.7333984375 m 534.5068359375 97.7333984375 l s q 0 0 1 rg BT 88.00 99.07 Td (Facility ) Tj ET Q q 0 0 1 rg BT 120.13 99.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 166.58 99.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 190.26 99.07 Td (as ) Tj ET Q q 0 0 1 rg BT 200.62 99.07 Td (of ) Tj ET Q q 0 0 1 rg BT 210.97 99.07 Td (September ) Tj ET Q q 0 0 1 rg BT 255.76 99.07 Td (29, ) Tj ET Q q 0 0 1 rg BT 270.29 99.07 Td (201) Tj ET Q q 0 0 1 rg BT 284.91 99.07 Td (1 ) Tj ET Q q 0 0 1 rg BT 291.94 99.07 Td (among ) Tj ET Q q 0 0 1 rg BT 321.18 99.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 379.32 99.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 409.68 99.07 Td (Company) Tj ET Q q 0 0 1 rg BT 447.92 99.07 Td (, ) Tj ET Q q 0 0 1 rg BT 452.44 99.07 Td (the ) Tj ET Q q 0 0 1 rg BT 466.69 99.07 Td (several ) Tj ET Q q 0 0 1 rg BT 497.03 99.07 Td (financial ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 87.7333984375 m 534.50146484375 87.7333984375 l s q 0 0 1 rg BT 88.00 89.07 Td (institutions ) Tj ET Q q 0 0 1 rg BT 135.55 89.07 Td (from ) Tj ET Q q 0 0 1 rg BT 158.08 89.07 Td (time ) Tj ET Q q 0 0 1 rg BT 178.94 89.07 Td (to ) Tj ET Q q 0 0 1 rg BT 189.82 89.07 Td (time ) Tj ET Q q 0 0 1 rg BT 210.68 89.07 Td (party ) Tj ET Q q 0 0 1 rg BT 234.32 89.07 Td (to ) Tj ET Q q 0 0 1 rg BT 245.19 89.07 Td (the ) Tj ET Q q 0 0 1 rg BT 260.50 89.07 Td (agreement, ) Tj ET Q q 0 0 1 rg BT 307.74 89.07 Td (and ) Tj ET Q q 0 0 1 rg BT 325.27 89.07 Td (JPMor) Tj ET Q q 0 0 1 rg BT 351.76 89.07 Td (gan ) Tj ET Q q 0 0 1 rg BT 369.30 89.07 Td (Chase ) Tj ET Q q 0 0 1 rg BT 396.83 89.07 Td (Bank, ) Tj ET Q q 0 0 1 rg BT 423.53 89.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 446.07 89.07 Td (and ) Tj ET Q q 0 0 1 rg BT 463.60 89.07 Td (Citibank ) Tj ET Q q 0 0 1 rg BT 501.13 89.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 523.67 89.07 Td (as ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 77.7333984375 m 534.4990234375 77.7333984375 l s q 0 0 1 rg BT 88.00 79.07 Td (administrative ) Tj ET Q q 0 0 1 rg BT 147.45 79.07 Td (agents ) Tj ET Q q 0 0 1 rg BT 175.23 79.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 231.33 79.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 258.56 79.07 Td (by ) Tj ET Q q 0 0 1 rg BT 270.80 79.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 310.22 79.07 Td (to ) Tj ET Q q 0 0 1 rg BT 320.23 79.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 351.92 79.07 Td (10a ) Tj ET Q q 0 0 1 rg BT 368.59 79.07 Td (to ) Tj ET Q q 0 0 1 rg BT 378.61 79.07 Td (the ) Tj ET Q q 0 0 1 rg BT 393.07 79.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 416.97 79.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 439.77 79.07 Td (for ) Tj ET Q q 0 0 1 rg BT 453.66 79.07 Td (the ) Tj ET Q q 0 0 1 rg BT 468.12 79.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 506.45 79.07 Td (period ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 67.7333984375 m 173.537109375 67.7333984375 l s q 0 0 1 rg BT 88.00 69.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 114.38 69.07 Td (June ) Tj ET Q q 0 0 1 rg BT 135.21 69.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 150.21 69.07 Td (2017\)) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 109.07 Td (‡) Tj ET Q endstream endobj 223 0 obj <> endobj 224 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.85 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 303.48 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 308.11 24.60 Td (1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 744.7333984375 m 78 744.7333984375 l s q 0 0 1 rg BT 60.50 746.07 Td (10g.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 744.7333984375 m 534.51220703125 744.7333984375 l s q 0 0 1 rg BT 88.00 746.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 140.64 746.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 165.50 746.07 Td (as ) Tj ET Q q 0 0 1 rg BT 177.04 746.07 Td (of ) Tj ET Q q 0 0 1 rg BT 188.57 746.07 Td (June ) Tj ET Q q 0 0 1 rg BT 210.11 746.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 225.81 746.07 Td (2017, ) Tj ET Q q 0 0 1 rg BT 251.52 746.07 Td (to ) Tj ET Q q 0 0 1 rg BT 262.50 746.07 Td (the ) Tj ET Q q 0 0 1 rg BT 277.92 746.07 Td (Five ) Tj ET Q q 0 0 1 rg BT 298.43 746.07 Td (Y) Tj ET Q q 0 0 1 rg BT 304.65 746.07 Td (ear ) Tj ET Q q 0 0 1 rg BT 320.07 746.07 Td (Competitive ) Tj ET Q q 0 0 1 rg BT 372.00 746.07 Td (Advance ) Tj ET Q q 0 0 1 rg BT 410.75 746.07 Td (and ) Tj ET Q q 0 0 1 rg BT 428.39 746.07 Td (Revolving ) Tj ET Q q 0 0 1 rg BT 473.26 746.07 Td (Credit ) Tj ET Q q 0 0 1 rg BT 501.46 746.07 Td (Facility ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 734.7333984375 m 534.5146484375 734.7333984375 l s q 0 0 1 rg BT 88.00 736.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 135.26 736.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 159.76 736.07 Td (as ) Tj ET Q q 0 0 1 rg BT 170.92 736.07 Td (of ) Tj ET Q q 0 0 1 rg BT 182.09 736.07 Td (July ) Tj ET Q q 0 0 1 rg BT 201.60 736.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 216.94 736.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 239.78 736.07 Td (among ) Tj ET Q q 0 0 1 rg BT 269.83 736.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 328.78 736.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 359.96 736.07 Td (Company) Tj ET Q q 0 0 1 rg BT 398.20 736.07 Td (, ) Tj ET Q q 0 0 1 rg BT 403.53 736.07 Td (the ) Tj ET Q q 0 0 1 rg BT 418.59 736.07 Td (several ) Tj ET Q q 0 0 1 rg BT 449.74 736.07 Td (financial ) Tj ET Q q 0 0 1 rg BT 487.56 736.07 Td (institutions ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 724.7333984375 m 534.513671875 724.7333984375 l s q 0 0 1 rg BT 88.00 726.07 Td (from ) Tj ET Q q 0 0 1 rg BT 109.78 726.07 Td (time ) Tj ET Q q 0 0 1 rg BT 129.90 726.07 Td (to ) Tj ET Q q 0 0 1 rg BT 140.02 726.07 Td (time ) Tj ET Q q 0 0 1 rg BT 160.14 726.07 Td (party ) Tj ET Q q 0 0 1 rg BT 183.03 726.07 Td (to ) Tj ET Q q 0 0 1 rg BT 193.15 726.07 Td (the ) Tj ET Q q 0 0 1 rg BT 207.71 726.07 Td (agreement, ) Tj ET Q q 0 0 1 rg BT 254.20 726.07 Td (and ) Tj ET Q q 0 0 1 rg BT 270.98 726.07 Td (JPMor) Tj ET Q q 0 0 1 rg BT 297.47 726.07 Td (gan ) Tj ET Q q 0 0 1 rg BT 314.25 726.07 Td (Chase ) Tj ET Q q 0 0 1 rg BT 341.04 726.07 Td (Bank, ) Tj ET Q q 0 0 1 rg BT 366.99 726.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 388.78 726.07 Td (and ) Tj ET Q q 0 0 1 rg BT 405.56 726.07 Td (Citibank ) Tj ET Q q 0 0 1 rg BT 442.35 726.07 Td (N.A. ) Tj ET Q q 0 0 1 rg BT 464.13 726.07 Td (as ) Tj ET Q q 0 0 1 rg BT 474.81 726.07 Td (administrative ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 714.7333984375 m 534.515625 714.7333984375 l s q 0 0 1 rg BT 88.00 716.07 Td (agents ) Tj ET Q q 0 0 1 rg BT 115.65 716.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 171.61 716.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 198.69 716.07 Td (by ) Tj ET Q q 0 0 1 rg BT 210.79 716.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 250.07 716.07 Td (to ) Tj ET Q q 0 0 1 rg BT 259.95 716.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 291.49 716.07 Td (10b ) Tj ET Q q 0 0 1 rg BT 308.59 716.07 Td (to ) Tj ET Q q 0 0 1 rg BT 318.46 716.07 Td (the ) Tj ET Q q 0 0 1 rg BT 332.78 716.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 356.55 716.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 379.20 716.07 Td (for ) Tj ET Q q 0 0 1 rg BT 392.96 716.07 Td (the ) Tj ET Q q 0 0 1 rg BT 407.27 716.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 445.47 716.07 Td (period ) Tj ET Q q 0 0 1 rg BT 473.11 716.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 499.09 716.07 Td (June ) Tj ET Q q 0 0 1 rg BT 519.52 716.07 Td (30, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 704.7833984375 m 111.330078125 704.7833984375 l s q 0 0 1 rg BT 88.00 706.12 Td (2017\)) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 746.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 688.7333984375 m 78 688.7333984375 l s q 0 0 1 rg BT 60.50 690.07 Td (10h.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 688.7333984375 m 534.49951171875 688.7333984375 l s q 0 0 1 rg BT 88.00 690.07 Td (SEC ) Tj ET Q q 0 0 1 rg BT 108.97 690.07 Td (Consent ) Tj ET Q q 0 0 1 rg BT 144.38 690.07 Td (Order ) Tj ET Q q 0 0 1 rg BT 170.32 690.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 226.81 690.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 254.43 690.07 Td (by ) Tj ET Q q 0 0 1 rg BT 267.06 690.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 306.87 690.07 Td (to ) Tj ET Q q 0 0 1 rg BT 317.27 690.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 349.35 690.07 Td (10s ) Tj ET Q q 0 0 1 rg BT 365.87 690.07 Td (to ) Tj ET Q q 0 0 1 rg BT 376.27 690.07 Td (the ) Tj ET Q q 0 0 1 rg BT 391.12 690.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 415.42 690.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 438.60 690.07 Td (for ) Tj ET Q q 0 0 1 rg BT 452.89 690.07 Td (the ) Tj ET Q q 0 0 1 rg BT 467.73 690.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 506.45 690.07 Td (period ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 678.7333984375 m 200.470703125 678.7333984375 l s q 0 0 1 rg BT 88.00 680.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 114.38 680.07 Td (September ) Tj ET Q q 0 0 1 rg BT 159.64 680.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 174.64 680.07 Td (2004\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 690.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 62.7 659.7333984375 m 77.9783203125 659.7333984375 l s q 0 0 1 rg BT 62.70 661.07 Td (10i.) 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Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 581.7333984375 m 534.4990234375 581.7333984375 l s q 0 0 1 rg BT 88.00 583.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 125.31 583.07 Td (Development ) Tj ET Q q 0 0 1 rg BT 182.06 583.07 Td (and ) Tj ET Q q 0 0 1 rg BT 199.37 583.07 Td (Commercialization ) Tj ET Q q 0 0 1 rg BT 278.89 583.07 Td (Collaboration ) Tj ET Q q 0 0 1 rg BT 336.12 583.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 383.42 583.07 Td (between ) Tj ET Q q 0 0 1 rg BT 419.61 583.07 Td (Otsuka ) Tj ET Q q 0 0 1 rg BT 450.82 583.07 Td (Pharmaceutical ) Tj ET Q q 0 0 1 rg BT 515.33 583.07 Td (Co., ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 571.7333984375 m 534.5126953125 571.7333984375 l s q 0 0 1 rg BT 88.00 573.07 Td (Ltd. ) Tj ET Q q 0 0 1 rg BT 105.86 573.07 Td (and ) Tj ET Q q 0 0 1 rg BT 121.77 573.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 179.35 573.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 209.17 573.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 249.53 573.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 272.66 573.07 Td (as ) Tj ET Q q 0 0 1 rg BT 282.46 573.07 Td (of ) Tj ET Q q 0 0 1 rg BT 292.26 573.07 Td (October ) Tj ET Q q 0 0 1 rg BT 325.95 573.07 Td (23, ) Tj ET Q q 0 0 1 rg BT 339.92 573.07 Td (2001 ) Tj ET Q q 0 0 1 rg BT 361.39 573.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 416.73 573.07 Td (by ) Tj ET Q q 0 0 1 rg BT 428.20 573.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 466.86 573.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 493.32 573.07 Td (to ) Tj ET Q q 0 0 1 rg BT 502.57 573.07 Td (Exhibit ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 561.7333984375 m 290.2119140625 561.7333984375 l s q 0 0 1 rg BT 88.00 563.07 Td (10.12 ) Tj ET Q q 0 0 1 rg BT 113.00 563.07 Td (to ) Tj ET Q q 0 0 1 rg BT 123.28 563.07 Td (the ) Tj ET Q q 0 0 1 rg BT 138.00 563.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 162.17 563.07 Td (8-K ) Tj ET Q q 0 0 1 rg BT 180.22 563.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 201.04 563.07 Td (on ) Tj ET Q q 0 0 1 rg BT 212.99 563.07 Td (August ) Tj ET Q q 0 0 1 rg BT 244.38 563.07 Td (17, ) Tj ET Q q 0 0 1 rg BT 259.38 563.07 Td (2009\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 583.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 62.7 540.7333984375 m 77.9783203125 540.7333984375 l s q 0 0 1 rg BT 62.70 542.07 Td (10l.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 540.7333984375 m 534.49755859375 540.7333984375 l s q 0 0 1 rg BT 88.00 542.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 141.40 542.07 Td (No. ) Tj ET Q q 0 0 1 rg BT 160.08 542.07 Td (3 ) Tj ET Q q 0 0 1 rg BT 169.05 542.07 Td (to ) Tj ET Q q 0 0 1 rg BT 180.79 542.07 Td (the ) Tj ET Q q 0 0 1 rg BT 196.97 542.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 235.37 542.07 Td (Development ) Tj ET Q q 0 0 1 rg BT 293.21 542.07 Td (and ) Tj ET Q q 0 0 1 rg BT 311.61 542.07 Td (Commercialization ) Tj ET Q q 0 0 1 rg BT 392.21 542.07 Td (Collaboration ) Tj ET Q q 0 0 1 rg BT 450.29 542.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 498.68 542.07 Td (between ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 530.7333984375 m 534.50244140625 530.7333984375 l s q 0 0 1 rg BT 88.00 532.07 Td (Otsuka ) Tj ET Q q 0 0 1 rg BT 121.69 532.07 Td (Pharmaceutical ) Tj ET Q q 0 0 1 rg BT 188.68 532.07 Td (Co., ) Tj ET Q q 0 0 1 rg BT 210.70 532.07 Td (Ltd. ) Tj ET Q q 0 0 1 rg BT 232.45 532.07 Td (and ) Tj ET Q q 0 0 1 rg BT 252.24 532.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 313.71 532.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 347.40 532.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 391.64 532.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 418.65 532.07 Td (as ) Tj ET Q q 0 0 1 rg BT 432.34 532.07 Td (of ) Tj ET Q q 0 0 1 rg BT 446.03 532.07 Td (September ) Tj ET Q q 0 0 1 rg BT 494.15 532.07 Td (25, ) Tj ET Q q 0 0 1 rg BT 512.00 532.07 Td (2006 ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 520.7333984375 m 468.4638671875 520.7333984375 l s q 0 0 1 rg BT 88.00 522.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 144.36 522.07 Td (by ) Tj ET Q q 0 0 1 rg BT 156.86 522.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 196.54 522.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 224.03 522.07 Td (to ) Tj ET Q q 0 0 1 rg BT 234.31 522.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 266.25 522.07 Td (10.13 ) Tj ET Q q 0 0 1 rg BT 291.25 522.07 Td (to ) Tj ET Q q 0 0 1 rg BT 301.53 522.07 Td (the ) Tj ET Q q 0 0 1 rg BT 316.25 522.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 340.42 522.07 Td (8-K ) Tj ET Q q 0 0 1 rg BT 358.47 522.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 379.29 522.07 Td (on ) Tj ET Q q 0 0 1 rg BT 391.24 522.07 Td (August ) Tj ET Q q 0 0 1 rg BT 422.63 522.07 Td (17, ) Tj ET Q q 0 0 1 rg BT 437.63 522.07 Td (2009\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 542.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 57.7 500.7333984375 m 77.9783203125 500.7333984375 l s q 0 0 1 rg BT 57.70 502.07 Td (10m.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 500.7333984375 m 534.4990234375 500.7333984375 l s q 0 0 1 rg BT 88.00 502.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 141.55 502.07 Td (No. 5 ) Tj ET Q q 0 0 1 rg BT 167.88 502.07 Td (to ) Tj ET Q q 0 0 1 rg BT 179.78 502.07 Td (the ) Tj ET Q q 0 0 1 rg BT 196.11 502.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 234.66 502.07 Td (Development ) Tj ET Q q 0 0 1 rg BT 292.64 502.07 Td (and ) Tj ET Q q 0 0 1 rg BT 311.19 502.07 Td (Commercialization ) Tj ET Q q 0 0 1 rg BT 391.95 502.07 Td (Collaboration ) Tj ET Q q 0 0 1 rg BT 450.15 502.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 498.68 502.07 Td (between ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 490.7333984375 m 534.505859375 490.7333984375 l s q 0 0 1 rg BT 88.00 492.07 Td (Otsuka ) Tj ET Q q 0 0 1 rg BT 118.39 492.07 Td (Pharmaceutical ) Tj ET Q q 0 0 1 rg BT 182.09 492.07 Td (Co., ) Tj ET Q q 0 0 1 rg BT 200.82 492.07 Td (Ltd. ) Tj ET Q q 0 0 1 rg BT 219.27 492.07 Td (and ) Tj ET Q q 0 0 1 rg BT 235.77 492.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 293.94 492.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 324.34 492.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 365.29 492.07 Td (ef) Tj ET Q q 0 0 1 rg BT 372.88 492.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 402.14 492.07 Td (as ) Tj ET Q q 0 0 1 rg BT 412.54 492.07 Td (of ) Tj ET Q q 0 0 1 rg BT 422.47 492.07 Td (April 4, ) Tj ET Q q 0 0 1 rg BT 455.64 492.07 Td (2009 \(incorporated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 480.7333984375 m 412.1015625 480.7333984375 l s q 0 0 1 rg BT 88.00 482.07 Td (by ) Tj ET Q q 0 0 1 rg BT 100.50 482.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 140.18 482.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 167.67 482.07 Td (to ) Tj ET Q q 0 0 1 rg BT 177.95 482.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 209.89 482.07 Td (10.14 ) Tj ET Q q 0 0 1 rg BT 234.89 482.07 Td (to ) Tj ET Q q 0 0 1 rg BT 245.17 482.07 Td (the ) Tj ET Q q 0 0 1 rg BT 259.88 482.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 284.05 482.07 Td (8-K ) Tj ET Q q 0 0 1 rg BT 302.11 482.07 Td (filed ) Tj ET Q q 0 0 1 rg BT 322.93 482.07 Td (on ) Tj ET Q q 0 0 1 rg BT 334.88 482.07 Td (August ) Tj ET Q q 0 0 1 rg BT 366.27 482.07 Td (17, ) Tj ET Q q 0 0 1 rg BT 381.27 482.07 Td (2009\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 502.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 459.7333984375 m 78 459.7333984375 l s q 0 0 1 rg BT 60.50 461.07 Td (10n.) 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Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 408.7333984375 m 532.00634765625 408.7333984375 l s q 0 0 1 rg BT 88.00 410.07 Td (Amended ) Tj ET Q q 0 0 1 rg BT 130.35 410.07 Td (and ) Tj ET Q q 0 0 1 rg BT 148.26 410.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 186.17 410.07 Td (Co-Development ) Tj ET Q q 0 0 1 rg BT 258.52 410.07 Td (and ) Tj ET Q q 0 0 1 rg BT 276.43 410.07 Td (Co-Promotion ) Tj ET Q q 0 0 1 rg BT 336.36 410.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 384.26 410.07 Td (\(Apixaban\) ) Tj ET Q q 0 0 1 rg BT 433.27 410.07 Td (by ) Tj ET Q q 0 0 1 rg BT 446.75 410.07 Td (and ) Tj ET Q q 0 0 1 rg BT 464.66 410.07 Td (between ) Tj ET Q q 0 0 1 rg BT 501.45 410.07 Td (Bristol-) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 398.7333984375 m 534.5146484375 398.7333984375 l s q 0 0 1 rg BT 88.00 400.07 Td (Myers ) Tj ET Q q 0 0 1 rg BT 116.53 400.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 147.85 400.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 189.71 400.07 Td (and ) Tj ET Q q 0 0 1 rg BT 207.13 400.07 Td (Pfizer) Tj ET Q q 0 0 1 rg BT 230.60 400.07 Td (, ) Tj ET Q q 0 0 1 rg BT 236.08 400.07 Td (Inc. ) Tj ET Q q 0 0 1 rg BT 254.33 400.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 278.30 400.07 Td (April ) Tj ET Q q 0 0 1 rg BT 302.39 400.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 317.87 400.07 Td (2007 ) Tj ET Q q 0 0 1 rg BT 340.84 400.07 Td (as ) Tj ET Q q 0 0 1 rg BT 352.15 400.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 391.22 400.07 Td (and ) Tj ET Q q 0 0 1 rg BT 408.64 400.07 Td (restated ) Tj ET Q q 0 0 1 rg BT 442.71 400.07 Td (as ) Tj ET Q q 0 0 1 rg BT 454.02 400.07 Td (of ) Tj ET Q q 0 0 1 rg BT 464.67 400.07 Td (August ) Tj ET Q q 0 0 1 rg BT 496.54 400.07 Td (23, ) Tj ET Q q 0 0 1 rg BT 512.01 400.07 Td (2007 ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 388.7333984375 m 532.0087890625 388.7333984375 l s q 0 0 1 rg BT 88.00 390.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 143.70 390.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 170.52 390.07 Td (by ) Tj ET Q q 0 0 1 rg BT 182.36 390.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 221.37 390.07 Td (to ) Tj ET Q q 0 0 1 rg BT 230.99 390.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 262.27 390.07 Td (10c ) Tj ET Q q 0 0 1 rg BT 278.54 390.07 Td (to ) Tj ET Q q 0 0 1 rg BT 288.16 390.07 Td (the ) Tj ET Q q 0 0 1 rg BT 302.21 390.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 325.71 390.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 348.10 390.07 Td (for ) Tj ET Q q 0 0 1 rg BT 361.60 390.07 Td (the ) Tj ET Q q 0 0 1 rg BT 375.65 390.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 413.58 390.07 Td (period ) Tj ET Q q 0 0 1 rg BT 440.96 390.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 466.68 390.07 Td (June ) Tj ET Q q 0 0 1 rg BT 486.84 390.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 501.18 390.07 Td (2016\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 410.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 369.7333984375 m 78 369.7333984375 l s q 0 0 1 rg BT 60.50 371.07 Td (10p.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 369.7333984375 m 534.49853515625 369.7333984375 l s q 0 0 1 rg BT 88.00 371.07 Td (Second ) Tj ET Q q 0 0 1 rg BT 119.63 371.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 171.88 371.07 Td (to ) Tj ET Q q 0 0 1 rg BT 181.85 371.07 Td (Amended ) Tj ET Q q 0 0 1 rg BT 223.54 371.07 Td (and ) Tj ET Q q 0 0 1 rg BT 240.80 371.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 278.05 371.07 Td (Co-Development ) Tj ET Q q 0 0 1 rg BT 349.73 371.07 Td (and ) Tj ET Q q 0 0 1 rg BT 366.99 371.07 Td (Co-Promotion ) Tj ET Q q 0 0 1 rg BT 426.41 371.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 473.65 371.07 Td (\(Apixaban\) ) Tj ET Q q 0 0 1 rg BT 522.00 371.07 Td (by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 359.7333984375 m 534.4990234375 359.7333984375 l s q 0 0 1 rg BT 88.00 361.07 Td (and ) Tj ET Q q 0 0 1 rg BT 105.04 361.07 Td (between ) Tj ET Q q 0 0 1 rg BT 140.95 361.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 199.66 361.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 230.59 361.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 272.08 361.07 Td (and ) Tj ET Q q 0 0 1 rg BT 289.11 361.07 Td ( Pfizer) Tj ET Q q 0 0 1 rg BT 315.09 361.07 Td (, ) Tj ET Q q 0 0 1 rg BT 320.19 361.07 Td (Inc. ) Tj ET Q q 0 0 1 rg BT 338.05 361.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 362.31 361.07 Td (as ) Tj ET Q q 0 0 1 rg BT 373.23 361.07 Td (of ) Tj ET Q q 0 0 1 rg BT 384.16 361.07 Td (March ) Tj ET Q q 0 0 1 rg BT 412.86 361.07 Td (15, ) Tj ET Q q 0 0 1 rg BT 427.96 361.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 450.55 361.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 507.01 361.07 Td (herein ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 349.7333984375 m 460.67578125 349.7333984375 l s q 0 0 1 rg BT 88.00 351.07 Td (by ) Tj ET Q q 0 0 1 rg BT 100.50 351.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 140.18 351.07 Td (to ) Tj ET Q q 0 0 1 rg BT 150.46 351.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 182.40 351.07 Td (10d ) Tj ET Q q 0 0 1 rg BT 199.90 351.07 Td (to ) Tj ET Q q 0 0 1 rg BT 210.18 351.07 Td (the ) Tj ET Q q 0 0 1 rg BT 224.90 351.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 249.07 351.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 272.12 351.07 Td (for ) Tj ET Q q 0 0 1 rg BT 286.28 351.07 Td (the ) Tj ET Q q 0 0 1 rg BT 301.00 351.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 339.59 351.07 Td (period ) Tj ET Q q 0 0 1 rg BT 367.64 351.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 394.02 351.07 Td (June ) Tj ET Q q 0 0 1 rg BT 414.85 351.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 429.85 351.07 Td (2016\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 371.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 330.7333984375 m 78 330.7333984375 l s q 0 0 1 rg BT 60.50 332.07 Td (10q.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 330.7333984375 m 534.50537109375 330.7333984375 l s q 0 0 1 rg BT 88.00 332.07 Td (Fourth ) Tj ET Q q 0 0 1 rg BT 117.07 332.07 Td (Amendment ) Tj ET Q q 0 0 1 rg BT 169.59 332.07 Td (to ) Tj ET Q q 0 0 1 rg BT 179.77 332.07 Td (Amended ) Tj ET Q q 0 0 1 rg BT 221.73 332.07 Td (and ) Tj ET Q q 0 0 1 rg BT 239.25 332.07 Td (Restated ) Tj ET Q q 0 0 1 rg BT 276.77 332.07 Td (Co-Development ) Tj ET Q q 0 0 1 rg BT 348.73 332.07 Td (and ) Tj ET Q q 0 0 1 rg BT 366.25 332.07 Td (Co-Promotion ) Tj ET Q q 0 0 1 rg BT 425.88 332.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 473.38 332.07 Td (\(Apixaban\) ) Tj ET Q q 0 0 1 rg BT 522.01 332.07 Td (by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 320.7333984375 m 534.5078125 320.7333984375 l s q 0 0 1 rg BT 88.00 322.07 Td (and ) Tj ET Q q 0 0 1 rg BT 104.89 322.07 Td (between ) Tj ET Q q 0 0 1 rg BT 140.66 322.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 199.22 322.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 230.01 322.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 271.35 322.07 Td (and ) Tj ET Q q 0 0 1 rg BT 288.24 322.07 Td (Pfizer) Tj ET Q q 0 0 1 rg BT 311.72 322.07 Td (, ) Tj ET Q q 0 0 1 rg BT 316.67 322.07 Td (Inc. ) Tj ET Q q 0 0 1 rg BT 334.39 322.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 358.50 322.07 Td (as ) Tj ET Q q 0 0 1 rg BT 369.28 322.07 Td (of ) Tj ET Q q 0 0 1 rg BT 380.07 322.07 Td (May ) Tj ET Q q 0 0 1 rg BT 400.85 322.07 Td (18, ) Tj ET Q q 0 0 1 rg BT 415.80 322.07 Td (2015 ) Tj ET Q q 0 0 1 rg BT 438.25 322.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 494.57 322.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 522.01 322.07 Td (by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 310.7333984375 m 447.6142578125 310.7333984375 l s q 0 0 1 rg BT 88.00 312.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 127.68 312.07 Td (to ) Tj ET Q q 0 0 1 rg BT 137.96 312.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 169.90 312.07 Td (10e ) Tj ET Q q 0 0 1 rg BT 186.84 312.07 Td (to ) Tj ET Q q 0 0 1 rg BT 197.12 312.07 Td (the ) Tj ET Q q 0 0 1 rg BT 211.84 312.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 236.01 312.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 259.06 312.07 Td (for ) Tj ET Q q 0 0 1 rg BT 273.22 312.07 Td (the ) Tj ET Q q 0 0 1 rg BT 287.94 312.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 326.53 312.07 Td (period ) Tj ET Q q 0 0 1 rg BT 354.58 312.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 380.95 312.07 Td (June ) Tj ET Q q 0 0 1 rg BT 401.78 312.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 416.78 312.07 Td (2016\).†) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 332.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 52.7 291.7333984375 m 77.9783203125 291.7333984375 l s q 0 0 1 rg BT 52.70 293.07 Td (‡‡10r) Tj ET Q q 0 0 1 rg BT 75.48 293.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 291.7333984375 m 534.5029296875 291.7333984375 l s q 0 0 1 rg BT 88.00 293.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 145.95 293.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 176.13 293.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 216.86 293.07 Td (2002 ) Tj ET Q q 0 0 1 rg BT 238.70 293.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 263.32 293.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 302.37 293.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 324.49 293.07 Td (ef) Tj ET Q q 0 0 1 rg BT 332.08 293.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 361.12 293.07 Td (as ) Tj ET Q q 0 0 1 rg BT 371.29 293.07 Td (of ) Tj ET Q q 0 0 1 rg BT 381.47 293.07 Td (May ) Tj ET Q q 0 0 1 rg BT 401.64 293.07 Td (7, ) Tj ET Q q 0 0 1 rg BT 410.98 293.07 Td (2002 ) Tj ET Q q 0 0 1 rg BT 432.82 293.07 Td (and ) Tj ET Q q 0 0 1 rg BT 449.10 293.07 Td (as ) Tj ET Q q 0 0 1 rg BT 459.28 293.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 497.21 293.07 Td (ef) Tj ET Q q 0 0 1 rg BT 504.80 293.07 Td (fective ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 281.7333984375 m 534.5009765625 281.7333984375 l s q 0 0 1 rg BT 88.00 283.07 Td (June ) Tj ET Q q 0 0 1 rg BT 108.60 283.07 Td (10, ) Tj ET Q q 0 0 1 rg BT 123.36 283.07 Td (2008 ) Tj ET Q q 0 0 1 rg BT 145.63 283.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 201.76 283.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 229.01 283.07 Td (by ) Tj ET Q q 0 0 1 rg BT 241.28 283.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 280.73 283.07 Td (to ) Tj ET Q q 0 0 1 rg BT 290.78 283.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 322.49 283.07 Td (10.1 ) Tj ET Q q 0 0 1 rg BT 342.25 283.07 Td (to ) Tj ET Q q 0 0 1 rg BT 352.30 283.07 Td (the ) Tj ET Q q 0 0 1 rg BT 366.78 283.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 390.72 283.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 413.54 283.07 Td (for ) Tj ET Q q 0 0 1 rg BT 427.47 283.07 Td (the ) Tj ET Q q 0 0 1 rg BT 441.95 283.07 Td (quarterly ) Tj ET Q q 0 0 1 rg BT 480.31 283.07 Td (period ) Tj ET Q q 0 0 1 rg BT 508.12 283.07 Td (ended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 271.7333984375 m 174.09375 271.7333984375 l s q 0 0 1 rg BT 88.00 273.07 Td (September ) Tj ET Q q 0 0 1 rg BT 133.26 273.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 148.26 273.07 Td (2008\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 293.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 51.6 252.7333984375 m 77.9916015625 252.7333984375 l s q 0 0 1 rg BT 51.60 254.07 Td (‡‡10s.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 252.7333984375 m 534.509765625 252.7333984375 l s q 0 0 1 rg BT 88.00 254.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.04 254.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 176.31 254.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 217.13 254.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 239.06 254.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 263.34 254.07 Td (A) Tj ET Q q 0 0 1 rg BT 269.65 254.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 291.57 254.07 Td (and ) Tj ET Q q 0 0 1 rg BT 307.94 254.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 347.07 254.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 369.28 254.07 Td (ef) Tj ET Q q 0 0 1 rg BT 376.87 254.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 406.00 254.07 Td (as ) Tj ET Q q 0 0 1 rg BT 416.26 254.07 Td (of ) Tj ET Q q 0 0 1 rg BT 426.52 254.07 Td (May ) Tj ET Q q 0 0 1 rg BT 446.79 254.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 456.22 254.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 478.15 254.07 Td (\(incorporated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 242.7333984375 m 429.0205078125 242.7333984375 l s q 0 0 1 rg BT 88.00 244.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 115.49 244.07 Td (by ) Tj ET Q q 0 0 1 rg BT 127.99 244.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 167.67 244.07 Td (to ) Tj ET Q q 0 0 1 rg BT 177.95 244.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 209.89 244.07 Td (B ) Tj ET Q q 0 0 1 rg BT 219.06 244.07 Td (to ) Tj ET Q q 0 0 1 rg BT 229.34 244.07 Td (the ) Tj ET Q q 0 0 1 rg BT 244.05 244.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 266.55 244.07 Td (Proxy ) Tj ET Q q 0 0 1 rg BT 292.95 244.07 Td (Statement ) Tj ET Q q 0 0 1 rg BT 335.44 244.07 Td (dated ) Tj ET Q q 0 0 1 rg BT 359.59 244.07 Td (March ) Tj ET Q q 0 0 1 rg BT 388.19 244.07 Td (20, ) Tj ET Q q 0 0 1 rg BT 403.19 244.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 254.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 52.7 223.7333984375 m 77.9783203125 223.7333984375 l s q 0 0 1 rg BT 52.70 225.07 Td (‡‡10t.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 223.7333984375 m 534.50732421875 223.7333984375 l s q 0 0 1 rg BT 88.00 225.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 145.51 225.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 175.25 225.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 215.54 225.07 Td (2007 ) Tj ET Q q 0 0 1 rg BT 236.95 225.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 260.82 225.07 Td (A) Tj ET Q q 0 0 1 rg BT 267.12 225.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 288.51 225.07 Td (and ) Tj ET Q q 0 0 1 rg BT 304.36 225.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 342.96 225.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 364.64 225.07 Td (ef) Tj ET Q q 0 0 1 rg BT 372.23 225.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 400.83 225.07 Td (as ) Tj ET Q q 0 0 1 rg BT 410.57 225.07 Td (of ) Tj ET Q q 0 0 1 rg BT 420.30 225.07 Td (May ) Tj ET Q q 0 0 1 rg BT 440.03 225.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 448.94 225.07 Td (2007 ) Tj ET Q q 0 0 1 rg BT 470.34 225.07 Td (and ) Tj ET Q q 0 0 1 rg BT 486.18 225.07 Td (as ) Tj ET Q q 0 0 1 rg BT 495.91 225.07 Td (amended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 213.7333984375 m 534.5087890625 213.7333984375 l s q 0 0 1 rg BT 88.00 215.07 Td (ef) Tj ET Q q 0 0 1 rg BT 95.59 215.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 126.05 215.07 Td (June ) Tj ET Q q 0 0 1 rg BT 147.64 215.07 Td (10, ) Tj ET Q q 0 0 1 rg BT 163.41 215.07 Td (2008 ) Tj ET Q q 0 0 1 rg BT 186.67 215.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 243.79 215.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 272.04 215.07 Td (by ) Tj ET Q q 0 0 1 rg BT 285.30 215.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 325.74 215.07 Td (to ) Tj ET Q q 0 0 1 rg BT 336.78 215.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 369.49 215.07 Td (10.2 ) Tj ET Q q 0 0 1 rg BT 390.25 215.07 Td (to ) Tj ET Q q 0 0 1 rg BT 401.29 215.07 Td (the ) Tj ET Q q 0 0 1 rg BT 416.77 215.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 441.70 215.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 465.51 215.07 Td (for ) Tj ET Q q 0 0 1 rg BT 480.44 215.07 Td (the ) Tj ET Q q 0 0 1 rg BT 495.92 215.07 Td (quarterly ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 203.7333984375 m 228.517578125 203.7333984375 l s q 0 0 1 rg BT 88.00 205.07 Td (period ) Tj ET Q q 0 0 1 rg BT 116.05 205.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 142.42 205.07 Td (September ) Tj ET Q q 0 0 1 rg BT 187.69 205.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 202.69 205.07 Td (2008\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 225.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 50.5 182.7333984375 m 78 182.7333984375 l s q 0 0 1 rg BT 50.50 184.07 Td (‡‡10u.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 182.7333984375 m 534.5107421875 182.7333984375 l s q 0 0 1 rg BT 88.00 184.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.04 184.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 176.32 184.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 217.00 184.07 Td (T) Tj ET Q q 0 0 1 rg BT 222.41 184.07 Td (eamShare ) Tj ET Q q 0 0 1 rg BT 263.76 184.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 288.48 184.07 Td (Option ) Tj ET Q q 0 0 1 rg BT 318.19 184.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 340.40 184.07 Td (as ) Tj ET Q q 0 0 1 rg BT 350.66 184.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 388.69 184.07 Td (and ) Tj ET Q q 0 0 1 rg BT 405.06 184.07 Td (restated ) Tj ET Q q 0 0 1 rg BT 438.09 184.07 Td (ef) Tj ET Q q 0 0 1 rg BT 445.68 184.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 474.81 184.07 Td (September ) Tj ET Q q 0 0 1 rg BT 519.51 184.07 Td (10, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 172.7333984375 m 534.5087890625 172.7333984375 l s q 0 0 1 rg BT 88.00 174.07 Td (2002 ) Tj ET Q q 0 0 1 rg BT 110.44 174.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 166.74 174.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 194.16 174.07 Td (by ) Tj ET Q q 0 0 1 rg BT 206.60 174.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 246.23 174.07 Td (to ) Tj ET Q q 0 0 1 rg BT 256.44 174.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 288.32 174.07 Td (10c ) Tj ET Q q 0 0 1 rg BT 305.20 174.07 Td (to ) Tj ET Q q 0 0 1 rg BT 315.42 174.07 Td (the ) Tj ET Q q 0 0 1 rg BT 330.08 174.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 354.18 174.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 377.17 174.07 Td (for ) Tj ET Q q 0 0 1 rg BT 391.27 174.07 Td (the ) Tj ET Q q 0 0 1 rg BT 405.93 174.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 430.02 174.07 Td (year ) Tj ET Q q 0 0 1 rg BT 449.67 174.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 475.99 174.07 Td (December ) Tj ET Q q 0 0 1 rg BT 519.51 174.07 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 162.7333984375 m 113.830078125 162.7333984375 l s q 0 0 1 rg BT 88.00 164.07 Td (2002\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 184.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 51.1 142.7333984375 m 77.9505859375 142.7333984375 l s q 0 0 1 rg BT 51.10 144.07 Td (‡‡10v) Tj ET Q q 0 0 1 rg BT 75.45 144.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 142.7333984375 m 534.501953125 142.7333984375 l s q 0 0 1 rg BT 88.00 144.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.13 144.07 Td (of ) Tj ET Q q 0 0 1 rg BT 122.92 144.07 Td (Non-Qualified ) Tj ET Q q 0 0 1 rg BT 183.70 144.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 208.94 144.07 Td (Option ) Tj ET Q q 0 0 1 rg BT 238.63 144.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 285.52 144.07 Td (under ) Tj ET Q q 0 0 1 rg BT 310.75 144.07 Td (the ) Tj ET Q q 0 0 1 rg BT 325.43 144.07 Td (2002 ) Tj ET Q q 0 0 1 rg BT 347.89 144.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 372.58 144.07 Td (A) Tj ET Q q 0 0 1 rg BT 378.89 144.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 401.34 144.07 Td (and ) Tj ET Q q 0 0 1 rg BT 418.24 144.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 457.90 144.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 478.14 144.07 Td (\(incorporated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 132.7333984375 m 482.0283203125 132.7333984375 l s q 0 0 1 rg BT 88.00 134.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 115.49 134.07 Td (by ) Tj ET Q q 0 0 1 rg BT 127.99 134.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 167.67 134.07 Td (to ) Tj ET Q q 0 0 1 rg BT 177.95 134.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 209.89 134.07 Td (10s ) Tj ET Q q 0 0 1 rg BT 226.28 134.07 Td (to ) Tj ET Q q 0 0 1 rg BT 236.56 134.07 Td (the ) Tj ET Q q 0 0 1 rg BT 251.28 134.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 275.45 134.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 298.50 134.07 Td (for ) Tj ET Q q 0 0 1 rg BT 312.66 134.07 Td (the ) Tj ET Q q 0 0 1 rg BT 327.38 134.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 351.53 134.07 Td (year ) Tj ET Q q 0 0 1 rg BT 371.24 134.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 397.61 134.07 Td (December ) Tj ET Q q 0 0 1 rg BT 441.20 134.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 456.20 134.07 Td (2005\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 144.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 48.9 110.7333984375 m 77.972265625 110.7333984375 l s q 0 0 1 rg BT 48.90 112.07 Td (‡‡10w) Tj ET Q q 0 0 1 rg BT 75.47 112.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 109.83339843749991 m 511.1494140625 109.83339843749991 l s q 0 0 1 rg BT 88.00 111.17 Td (Form of 2015-2017 Performance Share Units ) Tj ET Q q 0 0 1 rg BT 271.30 111.17 Td (Agreement under the 2012 Stock ) Tj ET Q q 0 0 1 rg BT 405.44 111.17 Td (A) Tj ET Q q 0 0 1 rg BT 411.74 111.17 Td (ward and Incentive Plan ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 99.83339843749991 m 512.013671875 99.83339843749991 l s q 0 0 1 rg BT 88.00 101.17 Td (\(incorporated by reference to Exhibit 10x to the Form 10-K for the fiscal year ended December 31, 2014\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 112.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 50.5 81.7333984375 m 78 81.7333984375 l s q 0 0 1 rg BT 50.50 83.07 Td (‡‡10x.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 80.83339843749991 m 511.1494140625 80.83339843749991 l s q 0 0 1 rg BT 88.00 82.17 Td (Form of 2016-2018 Performance Share Units ) Tj ET Q q 0 0 1 rg BT 271.30 82.17 Td (Agreement under the 2012 Stock ) Tj ET Q q 0 0 1 rg BT 405.44 82.17 Td (A) Tj ET Q q 0 0 1 rg BT 411.74 82.17 Td (ward and Incentive Plan ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 70.83339843749991 m 512.013671875 70.83339843749991 l s q 0 0 1 rg BT 88.00 72.17 Td (\(incorporated by reference to Exhibit 10y to the Form 10-K for the fiscal year ended December 31, 2015\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 83.07 Td (‡) Tj ET Q endstream endobj 225 0 obj <> endobj 226 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.65 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 303.28 24.60 Td (12) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 51.1 744.7333984375 m 77.9505859375 744.7333984375 l s q 0 0 1 rg BT 51.10 746.07 Td (‡‡10y) Tj ET Q q 0 0 1 rg BT 75.45 746.07 Td (.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 742.8333984374999 m 511.1494140625 742.8333984374999 l s q 0 0 1 rg BT 88.00 744.17 Td (Form of 2017-2019 Performance Share Units ) Tj ET Q q 0 0 1 rg BT 271.30 744.17 Td (Agreement under the 2012 Stock ) Tj ET Q q 0 0 1 rg BT 405.44 744.17 Td (A) Tj ET Q q 0 0 1 rg BT 411.74 744.17 Td (ward and Incentive Plan ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 732.8333984374999 m 515.890625 732.8333984374999 l s q 0 0 1 rg BT 88.00 734.17 Td (\(incorporated by reference to Exhibit 10ee to the Form 10-K for the fiscal year ended December 31, 2016\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 746.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 51.05 714.7333984375 m 77.9884765625 714.7333984375 l s q 0 0 1 rg BT 51.05 716.07 Td (‡‡10z.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 714.7333984375 m 534.5078125 714.7333984375 l s q 0 0 1 rg BT 88.00 716.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.12 716.07 Td (of ) Tj ET Q q 0 0 1 rg BT 122.89 716.07 Td (2018-2020 ) Tj ET Q q 0 0 1 rg BT 168.67 716.07 Td (Performance ) Tj ET Q q 0 0 1 rg BT 222.20 716.07 Td (Share ) Tj ET Q q 0 0 1 rg BT 247.41 716.07 Td (Units ) Tj ET Q q 0 0 1 rg BT 270.98 716.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 317.85 716.07 Td (under ) Tj ET Q q 0 0 1 rg BT 343.07 716.07 Td (the ) Tj ET Q q 0 0 1 rg BT 357.73 716.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 380.17 716.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 404.86 716.07 Td (A) Tj ET Q q 0 0 1 rg BT 411.16 716.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 433.60 716.07 Td (and ) Tj ET Q q 0 0 1 rg BT 450.48 716.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 490.13 716.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 510.35 716.07 Td (\(filed ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 704.7333984375 m 128.8154296875 704.7333984375 l s q 0 0 1 rg BT 88.00 706.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 714.7333984375 m 570.8685546875 714.7333984375 l s q 0 0 1 rg BT 543.10 716.07 Td (E-10-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 46.6 684.7333984375 m 77.976953125 684.7333984375 l s q 0 0 1 rg BT 46.60 686.07 Td (‡‡10aa.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 684.7333984375 m 534.50390625 684.7333984375 l s q 0 0 1 rg BT 88.00 686.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 111.58 686.07 Td (of ) Tj ET Q q 0 0 1 rg BT 121.83 686.07 Td (Restricted ) Tj ET Q q 0 0 1 rg BT 164.28 686.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 188.98 686.07 Td (Units ) Tj ET Q q 0 0 1 rg BT 212.14 686.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 258.48 686.07 Td (with ) Tj ET Q q 0 0 1 rg BT 278.17 686.07 Td (five ) Tj ET Q q 0 0 1 rg BT 295.63 686.07 Td (year ) Tj ET Q q 0 0 1 rg BT 314.75 686.07 Td (vesting ) Tj ET Q q 0 0 1 rg BT 345.55 686.07 Td (under ) Tj ET Q q 0 0 1 rg BT 370.23 686.07 Td (the ) Tj ET Q q 0 0 1 rg BT 384.36 686.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 406.28 686.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 430.55 686.07 Td (A) Tj ET Q q 0 0 1 rg BT 436.85 686.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 458.76 686.07 Td (and ) Tj ET Q q 0 0 1 rg BT 475.11 686.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 514.23 686.07 Td (Plan ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 674.7333984375 m 152.970703125 674.7333984375 l s q 0 0 1 rg BT 88.00 676.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 112.16 676.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 684.7333984375 m 570.8685546875 684.7333984375 l s q 0 0 1 rg BT 543.10 686.07 Td (E-10-2) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 654.7333984375 m 78 654.7333984375 l s q 0 0 1 rg BT 45.50 656.07 Td (‡‡10bb.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 654.7333984375 m 534.4990234375 654.7333984375 l s q 0 0 1 rg BT 88.00 656.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.78 656.07 Td (of ) Tj ET Q q 0 0 1 rg BT 124.22 656.07 Td (Restricted ) Tj ET Q q 0 0 1 rg BT 167.87 656.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 193.75 656.07 Td (Units ) Tj ET Q q 0 0 1 rg BT 217.84 656.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 265.38 656.07 Td (with ) Tj ET Q q 0 0 1 rg BT 286.26 656.07 Td (four ) Tj ET Q q 0 0 1 rg BT 306.03 656.07 Td (year ) Tj ET Q q 0 0 1 rg BT 326.34 656.07 Td (vesting ) Tj ET Q q 0 0 1 rg BT 358.34 656.07 Td (under ) Tj ET Q q 0 0 1 rg BT 384.22 656.07 Td (the ) Tj ET Q q 0 0 1 rg BT 399.54 656.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 422.65 656.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 447.85 656.07 Td (A) Tj ET Q q 0 0 1 rg BT 454.15 656.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 477.25 656.07 Td (and ) Tj ET Q q 0 0 1 rg BT 494.80 656.07 Td (Incentive ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 644.7333984375 m 173.2490234375 644.7333984375 l s q 0 0 1 rg BT 88.00 646.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 108.28 646.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 132.43 646.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 654.7333984375 m 570.8685546875 654.7333984375 l s q 0 0 1 rg BT 543.10 656.07 Td (E-10-3) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 46.6 624.7333984375 m 77.976953125 624.7333984375 l s q 0 0 1 rg BT 46.60 626.07 Td (‡‡10cc.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 624.7333984375 m 508.0830078125 624.7333984375 l s q 0 0 1 rg BT 88.00 626.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.17 626.07 Td (of ) Tj ET Q q 0 0 1 rg BT 123.00 626.07 Td (Market ) Tj ET Q q 0 0 1 rg BT 154.38 626.07 Td (Share ) Tj ET Q q 0 0 1 rg BT 179.65 626.07 Td (Units ) Tj ET Q q 0 0 1 rg BT 203.26 626.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 250.19 626.07 Td (under ) Tj ET Q q 0 0 1 rg BT 275.46 626.07 Td (the ) Tj ET Q q 0 0 1 rg BT 290.17 626.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 312.67 626.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 337.40 626.07 Td (A) Tj ET Q q 0 0 1 rg BT 343.70 626.07 Td (ward ) Tj ET Q q 0 0 1 rg BT 366.19 626.07 Td (and ) Tj ET Q q 0 0 1 rg BT 383.13 626.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 422.83 626.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 443.11 626.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 467.27 626.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 624.7333984375 m 570.8685546875 624.7333984375 l s q 0 0 1 rg BT 543.10 626.07 Td (E-10-4) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 595.7333984375 m 78 595.7333984375 l s q 0 0 1 rg BT 45.50 597.07 Td (‡‡10dd.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 595.7333984375 m 534.501953125 595.7333984375 l s q 0 0 1 rg BT 88.00 597.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 147.14 597.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 178.51 597.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 220.42 597.07 Td (Performance ) Tj ET Q q 0 0 1 rg BT 274.53 597.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 314.77 597.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 338.07 597.07 Td (as ) Tj ET Q q 0 0 1 rg BT 349.43 597.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 388.55 597.07 Td (\(as ) Tj ET Q q 0 0 1 rg BT 403.24 597.07 Td (adopted, ) Tj ET Q q 0 0 1 rg BT 440.43 597.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 493.99 597.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 522.00 597.07 Td (by ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 585.7333984375 m 534.4990234375 585.7333984375 l s q 0 0 1 rg BT 88.00 587.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 127.54 587.07 Td (to ) Tj ET Q q 0 0 1 rg BT 137.68 587.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 169.49 587.07 Td (2 ) Tj ET Q q 0 0 1 rg BT 176.85 587.07 Td (to ) Tj ET Q q 0 0 1 rg BT 186.99 587.07 Td (the ) Tj ET Q q 0 0 1 rg BT 201.56 587.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 225.60 587.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 248.51 587.07 Td (for ) Tj ET Q q 0 0 1 rg BT 262.53 587.07 Td (the ) Tj ET Q q 0 0 1 rg BT 277.11 587.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 301.12 587.07 Td (year ) Tj ET Q q 0 0 1 rg BT 320.69 587.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 346.93 587.07 Td (December ) Tj ET Q q 0 0 1 rg BT 390.37 587.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 405.23 587.07 Td (1978; ) Tj ET Q q 0 0 1 rg BT 430.37 587.07 Td (as ) Tj ET Q q 0 0 1 rg BT 441.06 587.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 479.52 587.07 Td (as ) Tj ET Q q 0 0 1 rg BT 490.21 587.07 Td (of ) Tj ET Q q 0 0 1 rg BT 500.90 587.07 Td (January ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 575.7333984375 m 534.513671875 575.7333984375 l s q 0 0 1 rg BT 88.00 577.07 Td (8, ) Tj ET Q q 0 0 1 rg BT 98.23 577.07 Td (1990, ) Tj ET Q q 0 0 1 rg BT 123.46 577.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 176.73 577.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 204.45 577.07 Td (by ) Tj ET Q q 0 0 1 rg BT 217.18 577.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 257.09 577.07 Td (to ) Tj ET Q q 0 0 1 rg BT 267.60 577.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 299.78 577.07 Td (19b ) Tj ET Q q 0 0 1 rg BT 317.51 577.07 Td (to ) Tj ET Q q 0 0 1 rg BT 328.02 577.07 Td (the ) Tj ET Q q 0 0 1 rg BT 342.97 577.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 367.37 577.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 390.65 577.07 Td (for ) Tj ET Q q 0 0 1 rg BT 405.05 577.07 Td (the ) Tj ET Q q 0 0 1 rg BT 419.99 577.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 444.38 577.07 Td (year ) Tj ET Q q 0 0 1 rg BT 464.32 577.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 490.93 577.07 Td (December ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 565.7333984375 m 534.51171875 565.7333984375 l s q 0 0 1 rg BT 88.00 567.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 102.63 567.07 Td (1990; ) Tj ET Q q 0 0 1 rg BT 127.54 567.07 Td (as ) Tj ET Q q 0 0 1 rg BT 138.01 567.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 176.23 567.07 Td (on ) Tj ET Q q 0 0 1 rg BT 187.90 567.07 Td (April ) Tj ET Q q 0 0 1 rg BT 211.14 567.07 Td (2, ) Tj ET Q q 0 0 1 rg BT 220.77 567.07 Td (1991, ) Tj ET Q q 0 0 1 rg BT 245.40 567.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 298.07 567.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 325.19 567.07 Td (by ) Tj ET Q q 0 0 1 rg BT 337.32 567.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 376.63 567.07 Td (to ) Tj ET Q q 0 0 1 rg BT 386.54 567.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 418.12 567.07 Td (19b ) Tj ET Q q 0 0 1 rg BT 435.25 567.07 Td (to ) Tj ET Q q 0 0 1 rg BT 445.17 567.07 Td (the ) Tj ET Q q 0 0 1 rg BT 459.51 567.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 483.32 567.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 506.00 567.07 Td (for ) Tj ET Q q 0 0 1 rg BT 519.79 567.07 Td (the ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 555.7333984375 m 534.5087890625 555.7333984375 l s q 0 0 1 rg BT 88.00 557.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 112.45 557.07 Td (year ) Tj ET Q q 0 0 1 rg BT 132.45 557.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 159.12 557.07 Td (December ) Tj ET Q q 0 0 1 rg BT 203.00 557.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 218.29 557.07 Td (1991; ) Tj ET Q q 0 0 1 rg BT 243.86 557.07 Td (as ) Tj ET Q q 0 0 1 rg BT 254.98 557.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 293.87 557.07 Td (ef) Tj ET Q q 0 0 1 rg BT 301.46 557.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 331.45 557.07 Td (January ) Tj ET Q q 0 0 1 rg BT 365.34 557.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 375.64 557.07 Td (1994, ) Tj ET Q q 0 0 1 rg BT 400.93 557.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 454.25 557.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 482.03 557.07 Td (by ) Tj ET Q q 0 0 1 rg BT 494.83 557.07 Td (reference ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 545.7333984375 m 534.5087890625 545.7333984375 l s q 0 0 1 rg BT 88.00 547.07 Td (to ) Tj ET Q q 0 0 1 rg BT 97.98 547.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 129.63 547.07 Td (10d ) Tj ET Q q 0 0 1 rg BT 146.83 547.07 Td (to ) Tj ET Q q 0 0 1 rg BT 156.81 547.07 Td (the ) Tj ET Q q 0 0 1 rg BT 171.23 547.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 195.10 547.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 217.85 547.07 Td (for ) Tj ET Q q 0 0 1 rg BT 231.72 547.07 Td (the ) Tj ET Q q 0 0 1 rg BT 246.13 547.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 269.99 547.07 Td (year ) Tj ET Q q 0 0 1 rg BT 289.40 547.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 315.48 547.07 Td (December ) Tj ET Q q 0 0 1 rg BT 358.77 547.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 373.47 547.07 Td (1993; ) Tj ET Q q 0 0 1 rg BT 398.45 547.07 Td (and ) Tj ET Q q 0 0 1 rg BT 415.09 547.07 Td (as ) Tj ET Q q 0 0 1 rg BT 425.62 547.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 463.92 547.07 Td (ef) Tj ET Q q 0 0 1 rg BT 471.51 547.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 500.91 547.07 Td (January ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 535.7333984375 m 534.513671875 535.7333984375 l s q 0 0 1 rg BT 88.00 537.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 98.23 537.07 Td (1994, ) Tj ET Q q 0 0 1 rg BT 123.46 537.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 176.73 537.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 204.45 537.07 Td (by ) Tj ET Q q 0 0 1 rg BT 217.18 537.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 257.09 537.07 Td (to ) Tj ET Q q 0 0 1 rg BT 267.60 537.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 299.78 537.07 Td (10d ) Tj ET Q q 0 0 1 rg BT 317.51 537.07 Td (to ) Tj ET Q q 0 0 1 rg BT 328.02 537.07 Td (the ) Tj ET Q q 0 0 1 rg BT 342.97 537.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 367.37 537.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 390.65 537.07 Td (for ) Tj ET Q q 0 0 1 rg BT 405.05 537.07 Td (the ) Tj ET Q q 0 0 1 rg BT 419.99 537.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 444.38 537.07 Td (year ) Tj ET Q q 0 0 1 rg BT 464.32 537.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 490.93 537.07 Td (December ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 525.7333984375 m 128.830078125 525.7333984375 l s q 0 0 1 rg BT 88.00 527.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 103.00 527.07 Td (1994\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 597.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 46.6 507.7333984375 m 77.976953125 507.7333984375 l s q 0 0 1 rg BT 46.60 509.07 Td (‡‡10ee.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 507.7333984375 m 534.5126953125 507.7333984375 l s q 0 0 1 rg BT 88.00 509.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.60 509.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 177.43 509.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 218.80 509.07 Td (Executive ) Tj ET Q q 0 0 1 rg BT 261.27 509.07 Td (Performance ) Tj ET Q q 0 0 1 rg BT 314.85 509.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 354.54 509.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 374.80 509.07 Td (ef) Tj ET Q q 0 0 1 rg BT 382.39 509.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 412.08 509.07 Td (January ) Tj ET Q q 0 0 1 rg BT 445.67 509.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 455.66 509.07 Td (1997 ) Tj ET Q q 0 0 1 rg BT 478.15 509.07 Td (\(incorporated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 497.7333984375 m 483.13671875 497.7333984375 l s q 0 0 1 rg BT 88.00 499.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 115.49 499.07 Td (by ) Tj ET Q q 0 0 1 rg BT 127.99 499.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 167.67 499.07 Td (to ) Tj ET Q q 0 0 1 rg BT 177.95 499.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 209.89 499.07 Td (10b ) Tj ET Q q 0 0 1 rg BT 227.39 499.07 Td (to ) Tj ET Q q 0 0 1 rg BT 237.67 499.07 Td (the ) Tj ET Q q 0 0 1 rg BT 252.38 499.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 276.55 499.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 299.61 499.07 Td (for ) Tj ET Q q 0 0 1 rg BT 313.77 499.07 Td (the ) Tj ET Q q 0 0 1 rg BT 328.48 499.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 352.64 499.07 Td (year ) Tj ET Q q 0 0 1 rg BT 372.35 499.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 398.72 499.07 Td (December ) Tj ET Q q 0 0 1 rg BT 442.31 499.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 457.31 499.07 Td (1996\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 509.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 49 477.7333984375 m 77.9794921875 477.7333984375 l s q 0 0 1 rg BT 49.00 479.07 Td (‡‡10f) Tj ET Q q 0 0 1 rg BT 72.15 479.07 Td (f.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 477.7333984375 m 534.50634765625 477.7333984375 l s q 0 0 1 rg BT 88.00 479.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 145.83 479.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 175.89 479.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 216.50 479.07 Td (Executive ) Tj ET Q q 0 0 1 rg BT 258.20 479.07 Td (Performance ) Tj ET Q q 0 0 1 rg BT 311.01 479.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 349.93 479.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 369.43 479.07 Td (ef) Tj ET Q q 0 0 1 rg BT 377.02 479.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 405.94 479.07 Td (January ) Tj ET Q q 0 0 1 rg BT 438.76 479.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 447.98 479.07 Td (2003 ) Tj ET Q q 0 0 1 rg BT 469.70 479.07 Td (and ) Tj ET Q q 0 0 1 rg BT 485.86 479.07 Td (as ) Tj ET Q q 0 0 1 rg BT 495.91 479.07 Td (amended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 467.7333984375 m 534.5087890625 467.7333984375 l s q 0 0 1 rg BT 88.00 469.07 Td (ef) Tj ET Q q 0 0 1 rg BT 95.59 469.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 126.05 469.07 Td (June ) Tj ET Q q 0 0 1 rg BT 147.64 469.07 Td (10, ) Tj ET Q q 0 0 1 rg BT 163.41 469.07 Td (2008 ) Tj ET Q q 0 0 1 rg BT 186.67 469.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 243.79 469.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 272.04 469.07 Td (by ) Tj ET Q q 0 0 1 rg BT 285.30 469.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 325.74 469.07 Td (to ) Tj ET Q q 0 0 1 rg BT 336.78 469.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 369.49 469.07 Td (10.3 ) Tj ET Q q 0 0 1 rg BT 390.25 469.07 Td (to ) Tj ET Q q 0 0 1 rg BT 401.29 469.07 Td (the ) Tj ET Q q 0 0 1 rg BT 416.77 469.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 441.70 469.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 465.51 469.07 Td (for ) Tj ET Q q 0 0 1 rg BT 480.44 469.07 Td (the ) Tj ET Q q 0 0 1 rg BT 495.92 469.07 Td (quarterly ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 457.7333984375 m 228.517578125 457.7333984375 l s q 0 0 1 rg BT 88.00 459.07 Td (period ) Tj ET Q q 0 0 1 rg BT 116.05 459.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 142.42 459.07 Td (September ) Tj ET Q q 0 0 1 rg BT 187.69 459.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 202.69 459.07 Td (2008\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 479.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 437.7333984375 m 78 437.7333984375 l s q 0 0 1 rg BT 45.50 439.07 Td (‡‡10gg.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 437.7333984375 m 534.5068359375 437.7333984375 l s q 0 0 1 rg BT 88.00 439.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 147.04 439.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 178.32 439.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 220.14 439.07 Td (2007 ) Tj ET Q q 0 0 1 rg BT 243.08 439.07 Td (Senior ) Tj ET Q q 0 0 1 rg BT 272.12 439.07 Td (Executive ) Tj ET Q q 0 0 1 rg BT 315.04 439.07 Td (Performance ) Tj ET Q q 0 0 1 rg BT 369.06 439.07 Td (Incentive ) Tj ET Q q 0 0 1 rg BT 409.20 439.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 429.91 439.07 Td (\(as ) Tj ET Q q 0 0 1 rg BT 444.51 439.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 483.54 439.07 Td (and ) Tj ET Q q 0 0 1 rg BT 500.91 439.07 Td (restated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 427.7333984375 m 534.5107421875 427.7333984375 l s q 0 0 1 rg BT 88.00 429.07 Td (ef) Tj ET Q q 0 0 1 rg BT 95.59 429.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 125.56 429.07 Td (June ) Tj ET Q q 0 0 1 rg BT 146.67 429.07 Td (8, ) Tj ET Q q 0 0 1 rg BT 156.94 429.07 Td (2010 ) Tj ET Q q 0 0 1 rg BT 179.71 429.07 Td (and ) Tj ET Q q 0 0 1 rg BT 196.92 429.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 250.23 429.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 277.98 429.07 Td (by ) Tj ET Q q 0 0 1 rg BT 290.76 429.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 330.71 429.07 Td (to ) Tj ET Q q 0 0 1 rg BT 341.26 429.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 373.48 429.07 Td (10a. ) Tj ET Q q 0 0 1 rg BT 393.19 429.07 Td (to ) Tj ET Q q 0 0 1 rg BT 403.74 429.07 Td (the ) Tj ET Q q 0 0 1 rg BT 418.73 429.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 443.17 429.07 Td (10-Q ) Tj ET Q q 0 0 1 rg BT 466.50 429.07 Td (for ) Tj ET Q q 0 0 1 rg BT 480.93 429.07 Td (the ) Tj ET Q q 0 0 1 rg BT 495.92 429.07 Td (quarterly ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 417.7333984375 m 204.083984375 417.7333984375 l s q 0 0 1 rg BT 88.00 419.07 Td (period ) Tj ET Q q 0 0 1 rg BT 116.05 419.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 142.42 419.07 Td (June ) Tj ET Q q 0 0 1 rg BT 163.25 419.07 Td (30, ) Tj ET Q q 0 0 1 rg BT 178.25 419.07 Td (2010\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 439.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 400.7333984375 m 78 400.7333984375 l s q 0 0 1 rg BT 45.50 402.07 Td (‡‡10hh.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 400.7333984375 m 534.51318359375 400.7333984375 l s q 0 0 1 rg BT 88.00 402.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.67 402.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 177.57 402.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 219.02 402.07 Td (Benefit ) Tj ET Q q 0 0 1 rg BT 251.01 402.07 Td (Equalization ) Tj ET Q q 0 0 1 rg BT 304.11 402.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 324.44 402.07 Td (– ) Tj ET Q q 0 0 1 rg BT 332.00 402.07 Td (Retirement ) Tj ET Q q 0 0 1 rg BT 378.99 402.07 Td (Income ) Tj ET Q q 0 0 1 rg BT 411.54 402.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 434.38 402.07 Td (as ) Tj ET Q q 0 0 1 rg BT 445.27 402.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 483.92 402.07 Td (and ) Tj ET Q q 0 0 1 rg BT 500.92 402.07 Td (restated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 390.7333984375 m 534.51708984375 390.7333984375 l s q 0 0 1 rg BT 88.00 392.07 Td (ef) Tj ET Q q 0 0 1 rg BT 95.59 392.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 124.69 392.07 Td (as ) Tj ET Q q 0 0 1 rg BT 134.91 392.07 Td (of ) Tj ET Q q 0 0 1 rg BT 145.14 392.07 Td (January ) Tj ET Q q 0 0 1 rg BT 178.13 392.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 187.53 392.07 Td (2012, ) Tj ET Q q 0 0 1 rg BT 211.92 392.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 267.68 392.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 294.56 392.07 Td (by ) Tj ET Q q 0 0 1 rg BT 306.46 392.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 345.54 392.07 Td (to ) Tj ET Q q 0 0 1 rg BT 355.21 392.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 386.55 392.07 Td (10ww ) Tj ET Q q 0 0 1 rg BT 412.89 392.07 Td (to ) Tj ET Q q 0 0 1 rg BT 422.57 392.07 Td (the ) Tj ET Q q 0 0 1 rg BT 436.68 392.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 460.25 392.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 482.69 392.07 Td (for ) Tj ET Q q 0 0 1 rg BT 496.25 392.07 Td (the ) Tj ET Q q 0 0 1 rg BT 510.36 392.07 Td (fiscal ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 380.7333984375 m 218.498046875 380.7333984375 l s q 0 0 1 rg BT 88.00 382.07 Td (year ) Tj ET Q q 0 0 1 rg BT 107.71 382.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 134.08 382.07 Td (December ) Tj ET Q q 0 0 1 rg BT 177.67 382.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 192.67 382.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 402.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 49.9 362.7333984375 m 77.956640625 362.7333984375 l s q 0 0 1 rg BT 49.90 364.07 Td (‡‡10ii.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 362.7333984375 m 534.50634765625 362.7333984375 l s q 0 0 1 rg BT 88.00 364.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.54 364.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 177.31 364.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 218.62 364.07 Td (Benefit ) Tj ET Q q 0 0 1 rg BT 250.49 364.07 Td (Equalization ) Tj ET Q q 0 0 1 rg BT 303.45 364.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 323.66 364.07 Td (– ) Tj ET Q q 0 0 1 rg BT 331.09 364.07 Td (Savings ) Tj ET Q q 0 0 1 rg BT 365.19 364.07 Td (and ) Tj ET Q q 0 0 1 rg BT 382.06 364.07 Td (Investment ) Tj ET Q q 0 0 1 rg BT 428.92 364.07 Td (Program, ) Tj ET Q q 0 0 1 rg BT 468.29 364.07 Td (as ) Tj ET Q q 0 0 1 rg BT 479.04 364.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 517.57 364.07 Td (and ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 352.7333984375 m 534.5009765625 352.7333984375 l s q 0 0 1 rg BT 88.00 354.07 Td (restated ) Tj ET Q q 0 0 1 rg BT 121.63 354.07 Td (ef) Tj ET Q q 0 0 1 rg BT 129.22 354.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 158.96 354.07 Td (as ) Tj ET Q q 0 0 1 rg BT 169.84 354.07 Td (of ) Tj ET Q q 0 0 1 rg BT 180.71 354.07 Td (January ) Tj ET Q q 0 0 1 rg BT 214.35 354.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 224.39 354.07 Td (2012 ) Tj ET Q q 0 0 1 rg BT 246.93 354.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 303.33 354.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 330.85 354.07 Td (by ) Tj ET Q q 0 0 1 rg BT 343.40 354.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 383.12 354.07 Td (to ) Tj ET Q q 0 0 1 rg BT 393.44 354.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 425.42 354.07 Td (10xx ) Tj ET Q q 0 0 1 rg BT 447.96 354.07 Td (to ) Tj ET Q q 0 0 1 rg BT 458.28 354.07 Td (the ) Tj ET Q q 0 0 1 rg BT 473.04 354.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 497.25 354.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 520.34 354.07 Td (for ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 342.7333984375 m 257.3701171875 342.7333984375 l s q 0 0 1 rg BT 88.00 344.07 Td (the ) Tj ET Q q 0 0 1 rg BT 102.72 344.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 126.87 344.07 Td (year ) Tj ET Q q 0 0 1 rg BT 146.58 344.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 172.96 344.07 Td (December ) Tj ET Q q 0 0 1 rg BT 216.54 344.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 231.54 344.07 Td (2012\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 364.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 49.9 324.7333984375 m 77.956640625 324.7333984375 l s q 0 0 1 rg BT 49.90 326.07 Td (‡‡10jj.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 324.7333984375 m 534.4990234375 324.7333984375 l s q 0 0 1 rg BT 88.00 326.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 118.16 326.07 Td (Corporation ) Tj ET Q q 0 0 1 rg BT 168.31 326.07 Td (Supplementary ) Tj ET Q q 0 0 1 rg BT 230.68 326.07 Td (Pension ) Tj ET Q q 0 0 1 rg BT 264.17 326.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 286.27 326.07 Td (as ) Tj ET Q q 0 0 1 rg BT 296.43 326.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 334.35 326.07 Td (\(as ) Tj ET Q q 0 0 1 rg BT 347.83 326.07 Td (previously ) Tj ET Q q 0 0 1 rg BT 391.87 326.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 429.79 326.07 Td (and ) Tj ET Q q 0 0 1 rg BT 446.05 326.07 Td (restated, ) Tj ET Q q 0 0 1 rg BT 481.47 326.07 Td (incorporated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 314.7333984375 m 534.513671875 314.7333984375 l s q 0 0 1 rg BT 88.00 316.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 115.62 316.07 Td (by ) Tj ET Q q 0 0 1 rg BT 128.25 316.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 168.06 316.07 Td (to ) Tj ET Q q 0 0 1 rg BT 178.47 316.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 210.55 316.07 Td (19g ) Tj ET Q q 0 0 1 rg BT 228.18 316.07 Td (to ) Tj ET Q q 0 0 1 rg BT 238.59 316.07 Td (the ) Tj ET Q q 0 0 1 rg BT 253.44 316.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 277.74 316.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 300.92 316.07 Td (for ) Tj ET Q q 0 0 1 rg BT 315.22 316.07 Td (the ) Tj ET Q q 0 0 1 rg BT 330.07 316.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 354.35 316.07 Td (year ) Tj ET Q q 0 0 1 rg BT 374.19 316.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 400.70 316.07 Td (December ) Tj ET Q q 0 0 1 rg BT 444.42 316.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 459.55 316.07 Td (1991; ) Tj ET Q q 0 0 1 rg BT 484.96 316.07 Td (as ) Tj ET Q q 0 0 1 rg BT 495.92 316.07 Td (amended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 304.7333984375 m 534.49658203125 304.7333984375 l s q 0 0 1 rg BT 88.00 306.07 Td (as ) Tj ET Q q 0 0 1 rg BT 99.09 306.07 Td (of ) Tj ET Q q 0 0 1 rg BT 110.18 306.07 Td (September ) Tj ET Q q 0 0 1 rg BT 155.71 306.07 Td (14, ) Tj ET Q q 0 0 1 rg BT 170.97 306.07 Td (1993, ) Tj ET Q q 0 0 1 rg BT 196.23 306.07 Td (and ) Tj ET Q q 0 0 1 rg BT 213.43 306.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 266.72 306.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 294.47 306.07 Td (by ) Tj ET Q q 0 0 1 rg BT 307.23 306.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 347.17 306.07 Td (to ) Tj ET Q q 0 0 1 rg BT 357.71 306.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 389.92 306.07 Td (10g ) Tj ET Q q 0 0 1 rg BT 407.68 306.07 Td (to ) Tj ET Q q 0 0 1 rg BT 418.22 306.07 Td (the ) Tj ET Q q 0 0 1 rg BT 433.20 306.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 457.63 306.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 480.94 306.07 Td (for ) Tj ET Q q 0 0 1 rg BT 495.36 306.07 Td (the ) Tj ET Q q 0 0 1 rg BT 510.34 306.07 Td (fiscal ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 294.7333984375 m 218.498046875 294.7333984375 l s q 0 0 1 rg BT 88.00 296.07 Td (year ) Tj ET Q q 0 0 1 rg BT 107.71 296.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 134.08 296.07 Td (December ) Tj ET Q q 0 0 1 rg BT 177.67 296.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 192.67 296.07 Td (1993\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 326.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 275.7333984375 m 78 275.7333984375 l s q 0 0 1 rg BT 45.50 277.07 Td (‡‡10kk.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 275.7333984375 m 534.51708984375 275.7333984375 l s q 0 0 1 rg BT 88.00 277.07 Td (Senior ) Tj ET Q q 0 0 1 rg BT 117.23 277.07 Td (Executive ) Tj ET Q q 0 0 1 rg BT 160.33 277.07 Td (Severance ) Tj ET Q q 0 0 1 rg BT 204.54 277.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 227.94 277.07 Td (ef) Tj ET Q q 0 0 1 rg BT 235.53 277.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 265.85 277.07 Td (as ) Tj ET Q q 0 0 1 rg BT 277.30 277.07 Td (of ) Tj ET Q q 0 0 1 rg BT 288.06 277.07 Td (April ) Tj ET Q q 0 0 1 rg BT 312.29 277.07 Td (26, ) Tj ET Q q 0 0 1 rg BT 327.92 277.07 Td (2007 ) Tj ET Q q 0 0 1 rg BT 351.04 277.07 Td (and ) Tj ET Q q 0 0 1 rg BT 368.60 277.07 Td (as ) Tj ET Q q 0 0 1 rg BT 380.05 277.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 419.26 277.07 Td (ef) Tj ET Q q 0 0 1 rg BT 426.85 277.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 457.18 277.07 Td (February ) Tj ET Q q 0 0 1 rg BT 496.40 277.07 Td (16, ) Tj ET Q q 0 0 1 rg BT 512.02 277.07 Td (2012 ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 265.7333984375 m 512.19921875 265.7333984375 l s q 0 0 1 rg BT 88.00 267.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 144.36 267.07 Td (by ) Tj ET Q q 0 0 1 rg BT 156.86 267.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 196.54 267.07 Td (to ) Tj ET Q q 0 0 1 rg BT 206.82 267.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 238.77 267.07 Td (10ll ) Tj ET Q q 0 0 1 rg BT 256.82 267.07 Td (to ) Tj ET Q q 0 0 1 rg BT 267.10 267.07 Td (the ) Tj ET Q q 0 0 1 rg BT 281.82 267.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 305.99 267.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 329.04 267.07 Td (for ) Tj ET Q q 0 0 1 rg BT 343.20 267.07 Td (the ) Tj ET Q q 0 0 1 rg BT 357.92 267.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 382.07 267.07 Td (year ) Tj ET Q q 0 0 1 rg BT 401.78 267.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 428.16 267.07 Td (December ) Tj ET Q q 0 0 1 rg BT 471.74 267.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 486.74 267.07 Td (201) Tj ET Q q 0 0 1 rg BT 501.37 267.07 Td (1\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 277.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 49.9 245.7333984375 m 77.956640625 245.7333984375 l s q 0 0 1 rg BT 49.90 247.07 Td (‡‡10ll.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 245.7333984375 m 534.49609375 245.7333984375 l s q 0 0 1 rg BT 88.00 247.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 112.69 247.07 Td (of ) Tj ET Q q 0 0 1 rg BT 123.38 247.07 Td (Agreement ) Tj ET Q q 0 0 1 rg BT 170.82 247.07 Td (entered ) Tj ET Q q 0 0 1 rg BT 203.27 247.07 Td (into ) Tj ET Q q 0 0 1 rg BT 221.85 247.07 Td (between ) Tj ET Q q 0 0 1 rg BT 258.19 247.07 Td (the ) Tj ET Q q 0 0 1 rg BT 273.43 247.07 Td (Registrant ) Tj ET Q q 0 0 1 rg BT 317.55 247.07 Td (and ) Tj ET Q q 0 0 1 rg BT 335.01 247.07 Td (each ) Tj ET Q q 0 0 1 rg BT 356.35 247.07 Td (of ) Tj ET Q q 0 0 1 rg BT 367.70 247.07 Td (the ) Tj ET Q q 0 0 1 rg BT 382.94 247.07 Td (named ) Tj ET Q q 0 0 1 rg BT 412.62 247.07 Td (executive ) Tj ET Q q 0 0 1 rg BT 453.95 247.07 Td (of) Tj ET Q q 0 0 1 rg BT 462.10 247.07 Td (ficers ) Tj ET Q q 0 0 1 rg BT 487.33 247.07 Td (and ) Tj ET Q q 0 0 1 rg BT 504.79 247.07 Td (certain ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 235.7333984375 m 534.51904296875 235.7333984375 l s q 0 0 1 rg BT 88.00 237.07 Td (other ) Tj ET Q q 0 0 1 rg BT 111.11 237.07 Td (executives ) Tj ET Q q 0 0 1 rg BT 155.87 237.07 Td (ef) Tj ET Q q 0 0 1 rg BT 163.46 237.07 Td (fective ) Tj ET Q q 0 0 1 rg BT 193.22 237.07 Td (January ) Tj ET Q q 0 0 1 rg BT 226.88 237.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 236.94 237.07 Td (2016 ) Tj ET Q q 0 0 1 rg BT 259.50 237.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 315.92 237.07 Td (by ) Tj ET Q q 0 0 1 rg BT 328.48 237.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 368.22 237.07 Td (to ) Tj ET Q q 0 0 1 rg BT 378.56 237.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 410.56 237.07 Td (10kk ) Tj ET Q q 0 0 1 rg BT 433.13 237.07 Td (to ) Tj ET Q q 0 0 1 rg BT 443.46 237.07 Td (the ) Tj ET Q q 0 0 1 rg BT 458.24 237.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 482.47 237.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 505.58 237.07 Td (for ) Tj ET Q q 0 0 1 rg BT 519.80 237.07 Td (the ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 225.7333984375 m 242.6533203125 225.7333984375 l s q 0 0 1 rg BT 88.00 227.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 112.16 227.07 Td (year ) Tj ET Q q 0 0 1 rg BT 131.86 227.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 158.24 227.07 Td (December ) Tj ET Q q 0 0 1 rg BT 201.82 227.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 216.82 227.07 Td (2015\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 247.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 39.9 206.7333984375 m 77.956640625 206.7333984375 l s q 0 0 1 rg BT 39.90 208.07 Td (‡‡10mm.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 206.7333984375 m 534.5087890625 206.7333984375 l s q 0 0 1 rg BT 88.00 208.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 147.27 208.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 178.78 208.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 220.83 208.07 Td (Retirement ) Tj ET Q q 0 0 1 rg BT 268.43 208.07 Td (Income ) Tj ET Q q 0 0 1 rg BT 301.58 208.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 322.53 208.07 Td (for ) Tj ET Q q 0 0 1 rg BT 337.35 208.07 Td (Non-Employee ) Tj ET Q q 0 0 1 rg BT 401.61 208.07 Td (Directors, ) Tj ET Q q 0 0 1 rg BT 444.49 208.07 Td (as ) Tj ET Q q 0 0 1 rg BT 455.98 208.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 495.24 208.07 Td (March ) Tj ET Q q 0 0 1 rg BT 524.51 208.07 Td (5, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 196.7333984375 m 534.4990234375 196.7333984375 l s q 0 0 1 rg BT 88.00 198.07 Td (1996 ) Tj ET Q q 0 0 1 rg BT 110.41 198.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 166.68 198.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 194.07 198.07 Td (by ) Tj ET Q q 0 0 1 rg BT 206.48 198.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 246.07 198.07 Td (to ) Tj ET Q q 0 0 1 rg BT 256.25 198.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 288.10 198.07 Td (10k ) Tj ET Q q 0 0 1 rg BT 305.51 198.07 Td (to ) Tj ET Q q 0 0 1 rg BT 315.70 198.07 Td (the ) Tj ET Q q 0 0 1 rg BT 330.32 198.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 354.40 198.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 377.36 198.07 Td (for ) Tj ET Q q 0 0 1 rg BT 391.42 198.07 Td (the ) Tj ET Q q 0 0 1 rg BT 406.05 198.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 430.11 198.07 Td (year ) Tj ET Q q 0 0 1 rg BT 449.72 198.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 476.01 198.07 Td (December ) Tj ET Q q 0 0 1 rg BT 519.50 198.07 Td (31, ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 186.7333984375 m 113.830078125 186.7333984375 l s q 0 0 1 rg BT 88.00 188.07 Td (1996\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 208.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 169.7333984375 m 78 169.7333984375 l s q 0 0 1 rg BT 45.50 171.07 Td (‡‡10nn.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 169.7333984375 m 534.5087890625 169.7333984375 l s q 0 0 1 rg BT 88.00 171.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 147.08 171.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 178.40 171.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 220.26 171.07 Td (1987 ) Tj ET Q q 0 0 1 rg BT 243.23 171.07 Td (Deferred ) Tj ET Q q 0 0 1 rg BT 281.73 171.07 Td (Compensation ) Tj ET Q q 0 0 1 rg BT 342.48 171.07 Td (Plan ) Tj ET Q q 0 0 1 rg BT 363.23 171.07 Td (for ) Tj ET Q q 0 0 1 rg BT 377.86 171.07 Td (Non-Employee ) Tj ET Q q 0 0 1 rg BT 441.93 171.07 Td (Directors, ) Tj ET Q q 0 0 1 rg BT 484.61 171.07 Td (as ) Tj ET Q q 0 0 1 rg BT 495.92 171.07 Td (amended ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 159.7333984375 m 534.5087890625 159.7333984375 l s q 0 0 1 rg BT 88.00 161.07 Td (and ) Tj ET Q q 0 0 1 rg BT 104.57 161.07 Td (restated ) Tj ET Q q 0 0 1 rg BT 137.79 161.07 Td (January ) Tj ET Q q 0 0 1 rg BT 171.02 161.07 Td (20, ) Tj ET Q q 0 0 1 rg BT 185.65 161.07 Td (2015 ) Tj ET Q q 0 0 1 rg BT 207.78 161.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 263.77 161.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 290.88 161.07 Td (by ) Tj ET Q q 0 0 1 rg BT 303.01 161.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 342.32 161.07 Td (to ) Tj ET Q q 0 0 1 rg BT 352.23 161.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 383.80 161.07 Td (10mm ) Tj ET Q q 0 0 1 rg BT 411.49 161.07 Td (to ) Tj ET Q q 0 0 1 rg BT 421.39 161.07 Td (the ) Tj ET Q q 0 0 1 rg BT 435.74 161.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 459.54 161.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 482.22 161.07 Td (for ) Tj ET Q q 0 0 1 rg BT 496.01 161.07 Td (the ) Tj ET Q q 0 0 1 rg BT 510.35 161.07 Td (fiscal ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 149.7333984375 m 218.498046875 149.7333984375 l s q 0 0 1 rg BT 88.00 151.07 Td (year ) Tj ET Q q 0 0 1 rg BT 107.71 151.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 134.08 151.07 Td (December ) Tj ET Q q 0 0 1 rg BT 177.67 151.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 192.67 151.07 Td (2014\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 171.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 130.7333984375 m 78 130.7333984375 l s q 0 0 1 rg BT 45.50 132.07 Td (‡‡10oo.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 130.7333984375 m 534.505859375 130.7333984375 l s q 0 0 1 rg BT 88.00 132.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.68 132.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 177.59 132.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 219.05 132.07 Td (Non-Employee ) Tj ET Q q 0 0 1 rg BT 282.72 132.07 Td (Directors’) Tj ET Q q 0 0 1 rg BT 322.51 132.07 Td ( ) Tj ET Q q 0 0 1 rg BT 325.08 132.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 350.44 132.07 Td (Option ) Tj ET Q q 0 0 1 rg BT 380.79 132.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 403.64 132.07 Td (as ) Tj ET Q q 0 0 1 rg BT 414.54 132.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 453.21 132.07 Td (\(as ) Tj ET Q q 0 0 1 rg BT 467.44 132.07 Td (approved ) Tj ET Q q 0 0 1 rg BT 507.22 132.07 Td (by ) Tj ET Q q 0 0 1 rg BT 519.79 132.07 Td (the ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 120.7333984375 m 534.51123046875 120.7333984375 l s q 0 0 1 rg BT 88.00 122.07 Td (Stockholders ) Tj ET Q q 0 0 1 rg BT 143.69 122.07 Td (on ) Tj ET Q q 0 0 1 rg BT 157.17 122.07 Td (May ) Tj ET Q q 0 0 1 rg BT 178.98 122.07 Td (1, ) Tj ET Q q 0 0 1 rg BT 189.96 122.07 Td (1990, ) Tj ET Q q 0 0 1 rg BT 215.94 122.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 269.95 122.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 298.41 122.07 Td (by ) Tj ET Q q 0 0 1 rg BT 311.89 122.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 352.55 122.07 Td (to ) Tj ET Q q 0 0 1 rg BT 363.81 122.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 396.73 122.07 Td (28 ) Tj ET Q q 0 0 1 rg BT 410.21 122.07 Td (to ) Tj ET Q q 0 0 1 rg BT 421.46 122.07 Td (Registration ) Tj ET Q q 0 0 1 rg BT 473.82 122.07 Td (Statement ) Tj ET Q q 0 0 1 rg BT 517.29 122.07 Td (No. ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 110.7333984375 m 534.5087890625 110.7333984375 l s q 0 0 1 rg BT 88.00 112.07 Td (33-38587 ) Tj ET Q q 0 0 1 rg BT 129.03 112.07 Td (on ) Tj ET Q q 0 0 1 rg BT 141.73 112.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 166.09 112.07 Td (S-8; ) Tj ET Q q 0 0 1 rg BT 185.46 112.07 Td (as ) Tj ET Q q 0 0 1 rg BT 196.49 112.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 235.28 112.07 Td (May ) Tj ET Q q 0 0 1 rg BT 256.31 112.07 Td (7, ) Tj ET Q q 0 0 1 rg BT 266.51 112.07 Td (1991, ) Tj ET Q q 0 0 1 rg BT 291.70 112.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 344.93 112.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 372.62 112.07 Td (by ) Tj ET Q q 0 0 1 rg BT 385.31 112.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 425.19 112.07 Td (to ) Tj ET Q q 0 0 1 rg BT 435.67 112.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 467.81 112.07 Td (19c ) Tj ET Q q 0 0 1 rg BT 484.95 112.07 Td (to ) Tj ET Q q 0 0 1 rg BT 495.42 112.07 Td (the ) Tj ET Q q 0 0 1 rg BT 510.34 112.07 Td (Form ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 100.7333984375 m 534.50146484375 100.7333984375 l s q 0 0 1 rg BT 88.00 102.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 109.93 102.07 Td (for ) Tj ET Q q 0 0 1 rg BT 122.96 102.07 Td (the ) Tj ET Q q 0 0 1 rg BT 136.55 102.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 159.58 102.07 Td (year ) Tj ET Q q 0 0 1 rg BT 178.16 102.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 203.42 102.07 Td (December ) Tj ET Q q 0 0 1 rg BT 245.87 102.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 259.75 102.07 Td (1991\), ) Tj ET Q q 0 0 1 rg BT 286.95 102.07 Td (as ) Tj ET Q q 0 0 1 rg BT 296.66 102.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 334.13 102.07 Td (January ) Tj ET Q q 0 0 1 rg BT 366.60 102.07 Td (12, ) Tj ET Q q 0 0 1 rg BT 380.47 102.07 Td (1999 ) Tj ET Q q 0 0 1 rg BT 401.85 102.07 Td (\(incorporated ) Tj ET Q q 0 0 1 rg BT 457.08 102.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 483.44 102.07 Td (by ) Tj ET Q q 0 0 1 rg BT 494.82 102.07 Td (reference ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 90.7333984375 m 406.2470703125 90.7333984375 l s q 0 0 1 rg BT 88.00 92.07 Td (to ) Tj ET Q q 0 0 1 rg BT 98.28 92.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 130.22 92.07 Td (10m ) Tj ET Q q 0 0 1 rg BT 150.50 92.07 Td (to ) Tj ET Q q 0 0 1 rg BT 160.78 92.07 Td (the ) Tj ET Q q 0 0 1 rg BT 175.50 92.07 Td (Form ) Tj ET Q q 0 0 1 rg BT 199.67 92.07 Td (10-K ) Tj ET Q q 0 0 1 rg BT 222.72 92.07 Td (for ) Tj ET Q q 0 0 1 rg BT 236.88 92.07 Td (the ) Tj ET Q q 0 0 1 rg BT 251.59 92.07 Td (fiscal ) Tj ET Q q 0 0 1 rg BT 275.75 92.07 Td (year ) Tj ET Q q 0 0 1 rg BT 295.46 92.07 Td (ended ) Tj ET Q q 0 0 1 rg BT 321.83 92.07 Td (December ) Tj ET Q q 0 0 1 rg BT 365.42 92.07 Td (31, ) Tj ET Q q 0 0 1 rg BT 380.42 92.07 Td (1998\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 132.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 45.5 73.7333984375 m 78 73.7333984375 l s q 0 0 1 rg BT 45.50 75.07 Td (‡‡10pp.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 73.7333984375 m 534.505859375 73.7333984375 l s q 0 0 1 rg BT 88.00 75.07 Td (Bristol-Myers ) Tj ET Q q 0 0 1 rg BT 146.68 75.07 Td (Squibb ) Tj ET Q q 0 0 1 rg BT 177.59 75.07 Td (Company ) Tj ET Q q 0 0 1 rg BT 219.05 75.07 Td (Non-Employee ) Tj ET Q q 0 0 1 rg BT 282.72 75.07 Td (Directors’) Tj ET Q q 0 0 1 rg BT 322.51 75.07 Td ( ) Tj ET Q q 0 0 1 rg BT 325.08 75.07 Td (Stock ) Tj ET Q q 0 0 1 rg BT 350.44 75.07 Td (Option ) Tj ET Q q 0 0 1 rg BT 380.79 75.07 Td (Plan, ) Tj ET Q q 0 0 1 rg BT 403.64 75.07 Td (as ) Tj ET Q q 0 0 1 rg BT 414.54 75.07 Td (amended ) Tj ET Q q 0 0 1 rg BT 453.21 75.07 Td (\(as ) Tj ET Q q 0 0 1 rg BT 467.44 75.07 Td (approved ) Tj ET Q q 0 0 1 rg BT 507.22 75.07 Td (by ) Tj ET Q q 0 0 1 rg BT 519.79 75.07 Td (the ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 63.7333984375 m 534.5048828125 63.7333984375 l s q 0 0 1 rg BT 88.00 65.07 Td (Stockholders ) Tj ET Q q 0 0 1 rg BT 142.68 65.07 Td (on ) Tj ET Q q 0 0 1 rg BT 155.14 65.07 Td (May ) Tj ET Q q 0 0 1 rg BT 175.94 65.07 Td (2, ) Tj ET Q q 0 0 1 rg BT 185.90 65.07 Td (2000, ) Tj ET Q q 0 0 1 rg BT 210.86 65.07 Td (incorporated ) Tj ET Q q 0 0 1 rg BT 263.86 65.07 Td (herein ) Tj ET Q q 0 0 1 rg BT 291.31 65.07 Td (by ) Tj ET Q q 0 0 1 rg BT 303.77 65.07 Td (reference ) Tj ET Q q 0 0 1 rg BT 343.42 65.07 Td (to ) Tj ET Q q 0 0 1 rg BT 353.66 65.07 Td (Exhibit ) Tj ET Q q 0 0 1 rg BT 385.02 65.07 Td (A) Tj ET Q q 0 0 1 rg BT 391.69 65.07 Td ( ) Tj ET Q q 0 0 1 rg BT 394.16 65.07 Td (to ) Tj ET Q q 0 0 1 rg BT 404.40 65.07 Td (the ) Tj ET Q q 0 0 1 rg BT 419.08 65.07 Td (2000 ) Tj ET Q q 0 0 1 rg BT 441.54 65.07 Td (Proxy ) Tj ET Q q 0 0 1 rg BT 467.90 65.07 Td (Statement ) Tj ET Q q 0 0 1 rg BT 510.35 65.07 Td (dated ) Tj ET Q BT /F1 10.00 Tf ET 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 53.7333984375 m 157.4287109375 53.7333984375 l s q 0 0 1 rg BT 88.00 55.07 Td (March ) Tj ET Q q 0 0 1 rg BT 116.60 55.07 Td (20, ) Tj ET Q q 0 0 1 rg BT 131.60 55.07 Td (2000\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 75.07 Td (‡) Tj ET Q endstream endobj 227 0 obj <> endobj 228 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 298.65 24.60 Td (1) Tj ET Q q 0 0 0 rg BT 303.28 24.60 Td (13) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 45.50 745.07 Td (‡‡10qq.) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 745.07 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 118.43 745.07 Td (Corporation ) Tj ET Q q 0 0 0 rg BT 168.85 745.07 Td (Deferral ) Tj ET Q q 0 0 0 rg BT 204.24 745.07 Td (Plan ) Tj ET Q q 0 0 0 rg BT 224.11 745.07 Td (for ) Tj ET Q q 0 0 0 rg BT 237.87 745.07 Td (Fees ) Tj ET Q q 0 0 0 rg BT 258.29 745.07 Td (of ) Tj ET Q q 0 0 0 rg BT 268.71 745.07 Td (Outside ) Tj ET Q q 0 0 0 rg BT 301.91 745.07 Td (Directors, ) Tj ET Q q 0 0 0 rg BT 343.71 745.07 Td (as ) Tj ET Q q 0 0 0 rg BT 354.13 745.07 Td (amended ) Tj ET Q q 0 0 0 rg BT 392.31 745.07 Td (\(as ) Tj ET Q q 0 0 0 rg BT 406.06 745.07 Td (adopted, ) Tj ET Q q 0 0 0 rg BT 442.31 745.07 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 494.93 745.07 Td (herein ) Tj ET Q q 0 0 0 rg BT 522.01 745.07 Td (by ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 735.07 Td (reference ) Tj ET Q q 0 0 0 rg BT 127.42 735.07 Td (to ) Tj ET Q q 0 0 0 rg BT 137.43 735.07 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 169.11 735.07 Td (10e ) Tj ET Q q 0 0 0 rg BT 185.79 735.07 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 216.36 735.07 Td (Corporation ) Tj ET Q q 0 0 0 rg BT 266.93 735.07 Td (1991 ) Tj ET Q q 0 0 0 rg BT 289.16 735.07 Td (Form ) Tj ET Q q 0 0 0 rg BT 313.07 735.07 Td (10-K ) Tj ET Q q 0 0 0 rg BT 335.86 735.07 Td (for ) Tj ET Q q 0 0 0 rg BT 349.75 735.07 Td (the ) Tj ET Q q 0 0 0 rg BT 364.21 735.07 Td (fiscal ) Tj ET Q q 0 0 0 rg BT 388.10 735.07 Td (year ) Tj ET Q q 0 0 0 rg BT 407.54 735.07 Td (ended ) Tj ET Q q 0 0 0 rg BT 433.65 735.07 Td (December ) Tj ET Q q 0 0 0 rg BT 476.97 735.07 Td (31, ) Tj ET Q q 0 0 0 rg BT 491.71 735.07 Td (1987, ) Tj ET Q q 0 0 0 rg BT 516.45 735.07 Td (File ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 725.07 Td (No. ) Tj ET Q q 0 0 0 rg BT 105.70 725.07 Td (1-5514; ) Tj ET Q q 0 0 0 rg BT 139.79 725.07 Td (as ) Tj ET Q q 0 0 0 rg BT 151.10 725.07 Td (amended ) Tj ET Q q 0 0 0 rg BT 190.17 725.07 Td (ef) Tj ET Q q 0 0 0 rg BT 197.85 725.07 Td (fective ) Tj ET Q q 0 0 0 rg BT 227.94 725.07 Td (December ) Tj ET Q q 0 0 0 rg BT 272.01 725.07 Td (31, ) Tj ET Q q 0 0 0 rg BT 287.49 725.07 Td (1991 ) Tj ET Q q 0 0 0 rg BT 310.47 725.07 Td (incorporated ) Tj ET Q q 0 0 0 rg BT 363.98 725.07 Td (herein ) Tj ET Q q 0 0 0 rg BT 391.95 725.07 Td (by ) Tj ET Q q 0 0 0 rg BT 404.93 725.07 Td (reference ) Tj ET Q q 0 0 0 rg BT 445.09 725.07 Td (to ) Tj ET Q q 0 0 0 rg BT 455.85 725.07 Td (Exhibit ) Tj ET Q q 0 0 0 rg BT 488.27 725.07 Td (10m ) Tj ET Q q 0 0 0 rg BT 509.03 725.07 Td (to ) Tj ET Q q 0 0 0 rg BT 519.79 725.07 Td (the ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 715.12 Td (Form ) Tj ET Q q 0 0 0 rg BT 112.17 715.12 Td (10-K ) Tj ET Q q 0 0 0 rg BT 135.22 715.12 Td (for ) Tj ET Q q 0 0 0 rg BT 149.38 715.12 Td (the ) Tj ET Q q 0 0 0 rg BT 164.10 715.12 Td (fiscal ) Tj ET Q q 0 0 0 rg BT 188.25 715.12 Td (year ) Tj ET Q q 0 0 0 rg BT 207.96 715.12 Td (ended ) Tj ET Q q 0 0 0 rg BT 234.34 715.12 Td (December ) Tj ET Q q 0 0 0 rg BT 277.92 715.12 Td (31, ) Tj ET Q q 0 0 0 rg BT 292.92 715.12 Td (1992\).) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 554.50 745.07 Td (‡) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 68 697.7333984375 m 78 697.7333984375 l s q 0 0 1 rg BT 68.00 699.07 Td (12) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 697.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 697.7333984375 m 293.7666015625 697.7333984375 l s q 0 0 1 rg BT 88.00 699.07 Td (Statement ) Tj ET Q q 0 0 1 rg BT 130.49 699.07 Td (re ) Tj ET Q q 0 0 1 rg BT 140.76 699.07 Td (computation ) Tj ET Q q 0 0 1 rg BT 193.25 699.07 Td (of ) Tj ET Q q 0 0 1 rg BT 204.08 699.07 Td (ratios ) Tj ET Q q 0 0 1 rg BT 228.80 699.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 252.95 699.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 697.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 697.7333984375 m 570.8685546875 697.7333984375 l s q 0 0 1 rg BT 543.10 699.07 Td (E-12-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 68 678.7333984375 m 78 678.7333984375 l s q 0 0 1 rg BT 68.00 680.07 Td (21) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 678.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 678.7333984375 m 273.5078125 678.7333984375 l s q 0 0 1 rg BT 88.00 680.07 Td (Subsidiaries ) Tj ET Q q 0 0 1 rg BT 139.39 680.07 Td (of ) Tj ET Q q 0 0 1 rg BT 150.22 680.07 Td (the ) Tj ET Q q 0 0 1 rg BT 164.93 680.07 Td (Registrant ) Tj ET Q q 0 0 1 rg BT 208.54 680.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 232.69 680.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 678.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 678.7333984375 m 570.8685546875 678.7333984375 l s q 0 0 1 rg BT 543.10 680.07 Td (E-21-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 68 659.7333984375 m 78 659.7333984375 l s q 0 0 1 rg BT 68.00 661.07 Td (23) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 659.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 659.7333984375 m 295.5830078125 659.7333984375 l s q 0 0 1 rg BT 88.00 661.07 Td (Consent ) Tj ET Q q 0 0 1 rg BT 123.28 661.07 Td (of ) Tj ET Q q 0 0 1 rg BT 134.11 661.07 Td (Deloitte ) Tj ET Q q 0 0 1 rg BT 168.82 661.07 Td (& ) Tj ET Q q 0 0 1 rg BT 178.92 661.07 Td (T) Tj ET Q q 0 0 1 rg BT 184.33 661.07 Td (ouche ) Tj ET Q q 0 0 1 rg BT 210.71 661.07 Td (LLP) Tj ET Q q 0 0 1 rg BT 228.11 661.07 Td ( ) Tj ET Q q 0 0 1 rg BT 230.61 661.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 254.77 661.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 659.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 659.7333984375 m 570.8685546875 659.7333984375 l s q 0 0 1 rg BT 543.10 661.07 Td (E-23-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 61.05 640.7333984375 m 77.9884765625 640.7333984375 l s q 0 0 1 rg BT 61.05 642.07 Td (31a.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 640.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 640.7333984375 m 282.375 640.7333984375 l s q 0 0 1 rg BT 88.00 642.07 Td (Section ) Tj ET Q q 0 0 1 rg BT 120.50 642.07 Td (302 ) Tj ET Q q 0 0 1 rg BT 138.00 642.07 Td (Certification ) Tj ET Q q 0 0 1 rg BT 191.03 642.07 Td (Letter ) Tj ET Q q 0 0 1 rg BT 217.40 642.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 241.56 642.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 640.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 640.7333984375 m 570.8685546875 640.7333984375 l s q 0 0 1 rg BT 543.10 642.07 Td (E-31-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 621.7333984375 m 78 621.7333984375 l s q 0 0 1 rg BT 60.50 623.07 Td (31b.) 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Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 621.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 621.7333984375 m 570.8685546875 621.7333984375 l s q 0 0 1 rg BT 543.10 623.07 Td (E-31-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 61.05 602.7333984375 m 77.9884765625 602.7333984375 l s q 0 0 1 rg BT 61.05 604.07 Td (32a.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 602.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 602.7333984375 m 282.375 602.7333984375 l s q 0 0 1 rg BT 88.00 604.07 Td (Section ) Tj ET Q q 0 0 1 rg BT 120.50 604.07 Td (906 ) Tj ET Q q 0 0 1 rg BT 138.00 604.07 Td (Certification ) Tj ET Q q 0 0 1 rg BT 191.03 604.07 Td (Letter ) Tj ET Q q 0 0 1 rg BT 217.40 604.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 241.56 604.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 602.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 602.7333984375 m 570.8685546875 602.7333984375 l s q 0 0 1 rg BT 543.10 604.07 Td (E-32-1) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 60.5 583.7333984375 m 78 583.7333984375 l s q 0 0 1 rg BT 60.50 585.07 Td (32b.) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 583.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 88 583.7333984375 m 282.375 583.7333984375 l s q 0 0 1 rg BT 88.00 585.07 Td (Section ) Tj ET Q q 0 0 1 rg BT 120.50 585.07 Td (906 ) Tj ET Q q 0 0 1 rg BT 138.00 585.07 Td (Certification ) Tj ET Q q 0 0 1 rg BT 191.03 585.07 Td (Letter ) Tj ET Q q 0 0 1 rg BT 217.40 585.07 Td (\(filed ) Tj ET Q q 0 0 1 rg BT 241.56 585.07 Td (herewith\).) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 583.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL 0 0 1 RG /GS0 gs 0.49 w 0 i [] 0 d 1 J 1 j 3 M 543.1 583.7333984375 m 570.8685546875 583.7333984375 l s q 0 0 1 rg BT 543.10 585.07 Td (E-32-2) Tj ET Q BT /F1 10.00 Tf ET 0 Tr /GS0 gs 0 Tw 0 Tc 100 Tz 0 TL BT /F1 10.00 Tf ET q 0 0 0 rg BT 60.50 566.07 Td (101.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 84.00 526.75 Td (  ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 566.07 Td (The ) Tj ET Q q 0 0 0 rg BT 106.25 566.07 Td (following ) Tj ET Q q 0 0 0 rg BT 147.84 566.07 Td (financial ) Tj ET Q q 0 0 0 rg BT 185.53 566.07 Td (statements ) Tj ET Q q 0 0 0 rg BT 230.44 566.07 Td (from ) Tj ET Q q 0 0 0 rg BT 252.58 566.07 Td (the ) Tj ET Q q 0 0 0 rg BT 267.51 566.07 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 326.32 566.07 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 357.36 566.07 Td (Company ) Tj ET Q q 0 0 0 rg BT 398.36 566.07 Td (Annual ) Tj ET Q q 0 0 0 rg BT 430.50 566.07 Td (Report ) Tj ET Q q 0 0 0 rg BT 460.42 566.07 Td (on ) Tj ET Q q 0 0 0 rg BT 473.12 566.07 Td (Form 10-K for ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 556.07 Td (the ) Tj ET Q q 0 0 0 rg BT 103.87 556.07 Td (years ) Tj ET Q q 0 0 0 rg BT 128.62 556.07 Td (ended ) Tj ET Q q 0 0 0 rg BT 156.14 556.07 Td (December 31, ) Tj ET Q q 0 0 0 rg BT 215.88 556.07 Td (2017, ) Tj ET Q q 0 0 0 rg BT 242.03 556.07 Td (2016 ) Tj ET Q q 0 0 0 rg BT 265.68 556.07 Td (and ) Tj ET Q q 0 0 0 rg BT 283.76 556.07 Td (2015, ) Tj ET Q q 0 0 0 rg BT 309.91 556.07 Td (formatted ) Tj ET Q q 0 0 0 rg BT 352.44 556.07 Td (in ) Tj ET Q q 0 0 0 rg BT 363.86 556.07 Td (Extensible ) Tj ET Q q 0 0 0 rg BT 409.73 556.07 Td (Business ) Tj ET Q q 0 0 0 rg BT 448.94 556.07 Td (Reporting ) Tj ET Q q 0 0 0 rg BT 492.58 556.07 Td (Language ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 546.07 Td (\(XBRL\): ) Tj ET Q q 0 0 0 rg BT 129.38 546.07 Td (\(i\) consolidated ) Tj ET Q q 0 0 0 rg BT 197.13 546.07 Td (statements ) Tj ET Q q 0 0 0 rg BT 244.62 546.07 Td (of ) Tj ET Q q 0 0 0 rg BT 258.22 546.07 Td (earnings, ) Tj ET Q q 0 0 0 rg BT 299.87 546.07 Td (\(ii\) ) Tj ET Q q 0 0 0 rg BT 317.36 546.07 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 373.17 546.07 Td (statements ) Tj ET Q q 0 0 0 rg BT 420.66 546.07 Td (of ) Tj ET Q q 0 0 0 rg BT 434.26 546.07 Td (comprehensive ) Tj ET Q q 0 0 0 rg BT 500.07 546.07 Td (income, ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 536.07 Td (\(iii\) consolidated ) Tj ET Q q 0 0 0 rg BT 158.04 536.07 Td (balance ) Tj ET Q q 0 0 0 rg BT 190.57 536.07 Td (sheets, ) Tj ET Q q 0 0 0 rg BT 219.51 536.07 Td (\(iv\) ) Tj ET Q q 0 0 0 rg BT 235.95 536.07 Td (consolidated ) Tj ET Q q 0 0 0 rg BT 288.50 536.07 Td (statements ) Tj ET Q q 0 0 0 rg BT 332.71 536.07 Td (of ) Tj ET Q q 0 0 0 rg BT 343.04 536.07 Td (cash ) Tj ET Q q 0 0 0 rg BT 362.81 536.07 Td (flows, ) Tj ET Q q 0 0 0 rg BT 389.54 536.07 Td (and ) Tj ET Q q 0 0 0 rg BT 405.98 536.07 Td (\(v\) the ) Tj ET Q q 0 0 0 rg BT 434.36 536.07 Td (notes ) Tj ET Q q 0 0 0 rg BT 457.47 536.07 Td (to ) Tj ET Q q 0 0 0 rg BT 467.25 536.07 Td (the ) Tj ET Q q 0 0 0 rg BT 481.47 536.07 Td (consolidated ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 88.00 526.07 Td (financial ) Tj ET Q q 0 0 0 rg BT 125.48 526.07 Td (statements.) Tj ET Q BT /F1 8.00 Tf ET q 0 0 0 rg BT 538.00 526.75 Td (    ) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 504.45 Td (†) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 56.00 503.07 Td (Confidential treatment has been granted for certain portions which are omitted in the copy of the exhibit electronically filed with) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 56.00 493.12 Td (the Commission.) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 39.00 460.45 Td (*) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 459.07 Td (Indicates, ) Tj ET Q q 0 0 0 rg BT 96.35 459.07 Td (in ) Tj ET Q q 0 0 0 rg BT 107.89 459.07 Td (this ) Tj ET Q q 0 0 0 rg BT 126.10 459.07 Td (Form ) Tj ET Q q 0 0 0 rg BT 151.53 459.07 Td (10-K, ) Tj ET Q q 0 0 0 rg BT 178.34 459.07 Td (brand ) Tj ET Q q 0 0 0 rg BT 204.86 459.07 Td (names ) Tj ET Q q 0 0 0 rg BT 234.17 459.07 Td (of ) Tj ET Q q 0 0 0 rg BT 246.26 459.07 Td (products, ) Tj ET Q q 0 0 0 rg BT 286.96 459.07 Td (which ) Tj ET Q q 0 0 0 rg BT 315.15 459.07 Td (are ) Tj ET Q q 0 0 0 rg BT 331.12 459.07 Td (registered ) Tj ET Q q 0 0 0 rg BT 374.30 459.07 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 422.48 459.07 Td (not ) Tj ET Q q 0 0 0 rg BT 439.02 459.07 Td (solely ) Tj ET Q q 0 0 0 rg BT 466.67 459.07 Td (owned ) Tj ET Q q 0 0 0 rg BT 497.08 459.07 Td (by ) Tj ET Q q 0 0 0 rg BT 510.84 459.07 Td (the ) Tj ET Q q 0 0 0 rg BT 526.82 459.07 Td (Company ) Tj ET Q q 0 0 0 rg BT 569.46 459.07 Td (or ) Tj ET Q q 0 0 0 rg BT 581.55 459.07 Td (its ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 449.07 Td (subsidiaries. ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 106.69 449.07 Td (Abilify) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 133.35 449.07 Td ( ) Tj ET Q q 0 0 0 rg BT 136.31 449.07 Td (is ) Tj ET Q q 0 0 0 rg BT 145.95 449.07 Td (a ) Tj ET Q q 0 0 0 rg BT 153.36 449.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 196.86 449.07 Td (of ) Tj ET Q q 0 0 0 rg BT 208.16 449.07 Td (Otsuka ) Tj ET Q q 0 0 0 rg BT 239.46 449.07 Td (Pharmaceutical ) Tj ET Q q 0 0 0 rg BT 304.06 449.07 Td (Co., ) Tj ET Q q 0 0 0 rg BT 323.70 449.07 Td (Ltd.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 345.84 449.07 Td (Adcetris) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 379.16 449.07 Td ( ) Tj ET Q q 0 0 0 rg BT 382.13 449.07 Td (is ) Tj ET Q q 0 0 0 rg BT 391.77 449.07 Td (a ) Tj ET Q q 0 0 0 rg BT 399.18 449.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 442.68 449.07 Td (of ) Tj ET Q q 0 0 0 rg BT 453.98 449.07 Td (Seattle ) Tj ET Q q 0 0 0 rg BT 484.16 449.07 Td (Genetics, ) Tj ET Q q 0 0 0 rg BT 524.61 449.07 Td (Inc.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 545.63 449.07 Td (Atripla) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.96 449.07 Td ( ) Tj ET Q q 0 0 0 rg BT 576.93 449.07 Td (is ) Tj ET Q q 0 0 0 rg BT 586.57 449.07 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 439.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 97.53 439.07 Td (of ) Tj ET Q q 0 0 0 rg BT 108.86 439.07 Td (Bristol-Myers ) Tj ET Q q 0 0 0 rg BT 167.96 439.07 Td (Squibb ) Tj ET Q q 0 0 0 rg BT 199.30 439.07 Td (and ) Tj ET Q q 0 0 0 rg BT 216.73 439.07 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 246.39 439.07 Td (Sciences, ) Tj ET Q q 0 0 0 rg BT 286.87 439.07 Td (LLC; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 311.53 439.07 Td (A) Tj ET Q q 0 0 0 rg BT 317.09 439.07 Td (vapr) Tj ET Q q 0 0 0 rg BT 335.05 439.07 Td (o/A) Tj ET Q q 0 0 0 rg BT 348.38 439.07 Td (valide) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 372.82 439.07 Td ( ) Tj ET Q q 0 0 0 rg BT 375.81 439.07 Td (\(known ) Tj ET Q q 0 0 0 rg BT 409.36 439.07 Td (in ) Tj ET Q q 0 0 0 rg BT 420.14 439.07 Td (the ) Tj ET Q q 0 0 0 rg BT 435.35 439.07 Td (EU ) Tj ET Q q 0 0 0 rg BT 451.68 439.07 Td (as ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 463.00 439.07 Td (Apr) Tj ET Q q 0 0 0 rg BT 477.63 439.07 Td (ovel/Karvea) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 526.51 439.07 Td (\) ) Tj ET Q q 0 0 0 rg BT 532.83 439.07 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 550.27 439.07 Td (Plavix) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 575.81 439.07 Td ( ) Tj ET Q q 0 0 0 rg BT 578.81 439.07 Td (are ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 429.07 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 101.36 429.07 Td (of ) Tj ET Q q 0 0 0 rg BT 112.62 429.07 Td (Sanofi; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 144.44 429.07 Td (Bydur) Tj ET Q q 0 0 0 rg BT 168.51 429.07 Td (eon, ) Tj ET Q q 0 0 0 rg BT 188.38 429.07 Td (Byetta) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 213.92 429.07 Td ( ) Tj ET Q q 0 0 0 rg BT 216.86 429.07 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 234.23 429.07 Td (Symlin) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 261.45 429.07 Td ( ) Tj ET Q q 0 0 0 rg BT 264.38 429.07 Td (are ) Tj ET Q q 0 0 0 rg BT 279.52 429.07 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 326.88 429.07 Td (of ) Tj ET Q q 0 0 0 rg BT 337.49 429.07 Td (Amylin ) Tj ET Q q 0 0 0 rg BT 370.98 429.07 Td (Pharmaceuticals, ) Tj ET Q q 0 0 0 rg BT 441.94 429.07 Td (LLC; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 466.54 429.07 Td (Cabometyx) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 511.53 429.07 Td ( ) Tj ET Q q 0 0 0 rg BT 514.46 429.07 Td (is ) Tj ET Q q 0 0 0 rg BT 524.07 429.07 Td (the ) Tj ET Q q 0 0 0 rg BT 539.22 429.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 582.68 429.07 Td (of ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 419.07 Td (Exelixis, ) Tj ET Q q 0 0 0 rg BT 90.99 419.07 Td (Inc.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 110.76 419.07 Td (ENHANZE) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 155.21 419.07 Td ( ) Tj ET Q q 0 0 0 rg BT 156.92 419.07 Td (is ) Tj ET Q q 0 0 0 rg BT 165.31 419.07 Td (a ) Tj ET Q q 0 0 0 rg BT 171.47 419.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 213.72 419.07 Td (of ) Tj ET Q q 0 0 0 rg BT 223.77 419.07 Td (Halozyme, ) Tj ET Q q 0 0 0 rg BT 269.08 419.07 Td (Inc.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 288.85 419.07 Td (Erbitux) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 318.84 419.07 Td ( ) Tj ET Q q 0 0 0 rg BT 320.56 419.07 Td (is ) Tj ET Q q 0 0 0 rg BT 328.95 419.07 Td (a ) Tj ET Q q 0 0 0 rg BT 335.11 419.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 377.36 419.07 Td (of ) Tj ET Q q 0 0 0 rg BT 387.41 419.07 Td (ImClone ) Tj ET Q q 0 0 0 rg BT 424.12 419.07 Td (LLC; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 447.51 419.07 Td (Farxiga ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 481.44 419.07 Td (and) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 495.88 419.07 Td ( ) Tj ET Q q 0 0 0 rg BT 497.60 419.07 Td (Onglyza ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 532.65 419.07 Td (are ) Tj ET Q q 0 0 0 rg BT 546.57 419.07 Td (trademarks ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 409.07 Td (of ) Tj ET Q q 0 0 0 rg BT 64.74 409.07 Td (AstraZeneca ) Tj ET Q q 0 0 0 rg BT 117.68 409.07 Td (AB; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 137.45 409.07 Td (Gleevec) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 169.64 409.07 Td ( ) Tj ET Q q 0 0 0 rg BT 172.74 409.07 Td (is ) Tj ET Q q 0 0 0 rg BT 182.51 409.07 Td (a ) Tj ET Q q 0 0 0 rg BT 190.04 409.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 233.68 409.07 Td (of ) Tj ET Q q 0 0 0 rg BT 245.10 409.07 Td (Novartis ) Tj ET Q q 0 0 0 rg BT 281.96 409.07 Td (AG; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 302.28 409.07 Td (Ixempra) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 335.60 409.07 Td ( ) Tj ET Q q 0 0 0 rg BT 338.69 409.07 Td (is ) Tj ET Q q 0 0 0 rg BT 348.46 409.07 Td (a ) Tj ET Q q 0 0 0 rg BT 356.00 409.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 399.63 409.07 Td (of ) Tj ET Q q 0 0 0 rg BT 411.06 409.07 Td (R-Pharm ) Tj ET Q q 0 0 0 rg BT 450.26 409.07 Td (US ) Tj ET Q q 0 0 0 rg BT 466.15 409.07 Td (Operating, ) Tj ET Q q 0 0 0 rg BT 511.73 409.07 Td (LLC; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 536.49 409.07 Td (Keytruda) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 573.71 409.07 Td ( ) Tj ET Q q 0 0 0 rg BT 576.81 409.07 Td (is ) Tj ET Q q 0 0 0 rg BT 586.58 409.07 Td (a ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 399.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 97.12 399.07 Td (of ) Tj ET Q q 0 0 0 rg BT 108.04 399.07 Td (Merck ) Tj ET Q q 0 0 0 rg BT 136.72 399.07 Td (Sharp ) Tj ET Q q 0 0 0 rg BT 162.64 399.07 Td (& ) Tj ET Q q 0 0 0 rg BT 173.00 399.07 Td (Dohme ) Tj ET Q q 0 0 0 rg BT 205.03 399.07 Td (Corp.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 232.89 399.07 Td (Myalept) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 265.66 399.07 Td ( ) Tj ET Q q 0 0 0 rg BT 268.25 399.07 Td (is ) Tj ET Q q 0 0 0 rg BT 277.50 399.07 Td (a ) Tj ET Q q 0 0 0 rg BT 284.53 399.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 327.65 399.07 Td (of ) Tj ET Q q 0 0 0 rg BT 337.99 399.07 Td (Aegerion ) Tj ET Q q 0 0 0 rg BT 377.79 399.07 Td (Pharmaceuticals, ) Tj ET Q q 0 0 0 rg BT 448.40 399.07 Td (Inc.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 469.03 399.07 Td (Pr) Tj ET Q q 0 0 0 rg BT 478.66 399.07 Td (ostvac) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 504.21 399.07 Td ( ) Tj ET Q q 0 0 0 rg BT 506.80 399.07 Td (is ) Tj ET Q q 0 0 0 rg BT 516.05 399.07 Td (a ) Tj ET Q q 0 0 0 rg BT 523.08 399.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 566.20 399.07 Td (of ) Tj ET Q q 0 0 0 rg BT 577.12 399.07 Td (BN ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 389.07 Td (ImmunoTherapeutics ) Tj ET Q q 0 0 0 rg BT 141.73 389.07 Td (Inc.; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 161.99 389.07 Td (Recothr) Tj ET Q q 0 0 0 rg BT 193.27 389.07 Td (om) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 205.49 389.07 Td ( ) Tj ET Q q 0 0 0 rg BT 207.70 389.07 Td (is ) Tj ET Q q 0 0 0 rg BT 216.58 389.07 Td (a ) Tj ET Q q 0 0 0 rg BT 223.22 389.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 265.96 389.07 Td (of ) Tj ET Q q 0 0 0 rg BT 276.34 389.07 Td (The ) Tj ET Q q 0 0 0 rg BT 294.09 389.07 Td (Medicines ) Tj ET Q q 0 0 0 rg BT 337.96 389.07 Td (Company; ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 381.83 389.07 Td (Rubraca) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 416.27 389.07 Td ( ) Tj ET Q q 0 0 0 rg BT 418.47 389.07 Td (is ) Tj ET Q q 0 0 0 rg BT 427.35 389.07 Td (a ) Tj ET Q q 0 0 0 rg BT 434.00 389.07 Td (trademark ) Tj ET Q q 0 0 0 rg BT 476.74 389.07 Td (of ) Tj ET Q q 0 0 0 rg BT 487.27 389.07 Td (Clovis ) Tj ET Q q 0 0 0 rg BT 515.60 389.07 Td (Oncology) Tj ET Q q 0 0 0 rg BT 554.39 389.07 Td (, ) Tj ET Q q 0 0 0 rg BT 559.09 389.07 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 576.57 389.07 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 54.00 379.06 Td (T) Tj ET Q q 0 0 0 rg BT 59.01 379.06 Td (ruvada) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 87.34 379.06 Td ( ) Tj ET Q q 0 0 0 rg BT 89.59 379.06 Td (and ) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 106.28 379.06 Td (T) Tj ET Q q 0 0 0 rg BT 111.10 379.06 Td (ybost ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 134.46 379.06 Td (are) Tj ET Q BT /F3 10.00 Tf ET q 0 0 0 rg BT 146.66 379.06 Td ( ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 148.91 379.06 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 195.59 379.06 Td (of ) Tj ET Q q 0 0 0 rg BT 206.17 379.06 Td (Gilead ) Tj ET Q q 0 0 0 rg BT 235.07 379.06 Td (Sciences, ) Tj ET Q q 0 0 0 rg BT 274.81 379.06 Td (Inc. ) Tj ET Q q 0 0 0 rg BT 292.33 379.06 Td (and/or ) Tj ET Q q 0 0 0 rg BT 320.12 379.06 Td (one ) Tj ET Q q 0 0 0 rg BT 336.81 379.06 Td (of ) Tj ET Q q 0 0 0 rg BT 347.39 379.06 Td (its ) Tj ET Q q 0 0 0 rg BT 359.09 379.06 Td (af) Tj ET Q q 0 0 0 rg BT 366.68 379.06 Td (filiates. ) Tj ET Q q 0 0 0 rg BT 398.64 379.06 Td (Brand ) Tj ET Q q 0 0 0 rg BT 425.33 379.06 Td (names ) Tj ET Q q 0 0 0 rg BT 453.13 379.06 Td (of ) Tj ET Q q 0 0 0 rg BT 463.71 379.06 Td (products ) Tj ET Q q 0 0 0 rg BT 500.39 379.06 Td (that ) Tj ET Q q 0 0 0 rg BT 517.64 379.06 Td (are ) Tj ET Q q 0 0 0 rg BT 532.10 379.06 Td (in ) Tj ET Q q 0 0 0 rg BT 542.12 379.06 Td (all ) Tj ET Q q 0 0 0 rg BT 554.37 379.06 Td (italicized ) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 54.00 369.12 Td (letters, ) Tj ET Q q 0 0 0 rg BT 83.43 369.12 Td (without ) Tj ET Q q 0 0 0 rg BT 116.49 369.12 Td (an ) Tj ET Q q 0 0 0 rg BT 128.43 369.12 Td (asterisk, ) Tj ET Q q 0 0 0 rg BT 163.98 369.12 Td (are ) Tj ET Q q 0 0 0 rg BT 178.68 369.12 Td (registered ) Tj ET Q q 0 0 0 rg BT 220.61 369.12 Td (trademarks ) Tj ET Q q 0 0 0 rg BT 267.53 369.12 Td (of ) Tj ET Q q 0 0 0 rg BT 278.36 369.12 Td (BMS ) Tj ET Q q 0 0 0 rg BT 301.98 369.12 Td (and/or ) Tj ET Q q 0 0 0 rg BT 330.03 369.12 Td (one ) Tj ET Q q 0 0 0 rg BT 346.97 369.12 Td (of ) Tj ET Q q 0 0 0 rg BT 357.80 369.12 Td (its ) Tj ET Q q 0 0 0 rg BT 369.75 369.12 Td (subsidiaries.) 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Tj ET Q BT /F1 9.00 Tf ET q 0 0 0 rg BT 50.00 629.45 Td ( ) Tj ET Q 0 0 0 RG /GS0 gs 1.00 w 0 i [] 0 d 0 J 0 j 3 M 50.5 589.95 m 182.5 589.95 l s BT /F1 10.00 Tf ET q 0 0 0 rg BT 62.45 594.52 Td (/s/ GIOV) Tj ET Q q 0 0 0 rg BT 98.75 594.52 Td (ANNI CAFORIO) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 80.85 580.52 Td (Giovanni Caforio) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 68.05 565.62 Td (Chief Executive Of) Tj ET Q q 0 0 0 rg BT 145.71 565.62 Td (ficer) Tj ET Q BT /F1 10.00 Tf ET q 0 0 0 rg BT 79.20 550.62 Td (February 13, 2018) Tj ET Q BT /F1 10.00 Tf ET BT /F1 8.00 Tf ET q 0 0 0 rg BT 50.00 536.85 Td ( ) Tj ET Q endstream endobj 245 0 obj <> endobj 246 0 obj <> stream BT /F1 10.00 Tf ET q 0 0 0 rg BT 292.10 21.00 Td (E-32-2) Tj ET Q BT /F2 10.00 Tf ET q 0 0 0 rg BT 498.80 742.25 Td (EXHIBIT) Tj ET Q q 0 0 0 rg BT 541.41 742.25 Td ( 32b.) 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