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pRRophetic: An R Package for Prediction of Clinical Chemotherapeutic Response from Tumor Gene Expression Levels

Figure 1

The prediction accuracy achieved in external datasets.

(a) A boxplot showing the predicted clinical bortezomib sensitivity for multiple myeloma patients. The predictions where made using the pRRopheticPredict() function for only hematological cancer cell lines. (NR, Clinical Non-responders; R, Clinical Responders) (b) The predicted PD0325901 sensitivity in CCLE, plotted against the measured activity area (a measure of drug response) in CCLE. A linear regression line and 95% confidence intervals are included.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0107468.g001